879212:DESPODRAFT RS09070
gene id: 879212:DESPODRAFT_RS09070
uniprot id: I5B2M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

879212:DESPODRAFT RS01355
gene id: 879212:DESPODRAFT_RS01355
uniprot id: I5AYH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

879212:DESPODRAFT RS14005
gene id: 879212:DESPODRAFT_RS14005
uniprot id: I5B5A6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

879212:DESPODRAFT RS05505
gene id: 879212:DESPODRAFT_RS05505
uniprot id: I5B0Q7
names: Similarity
messages: Belongs to the sigma-54 factor family.

879212:DESPODRAFT RS16485
gene id: 879212:DESPODRAFT_RS16485
uniprot id: I5B6N2
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS00460
gene id: 879212:DESPODRAFT_RS00460
uniprot id: I5AY08
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

879212:DESPODRAFT RS16595
gene id: 879212:DESPODRAFT_RS16595
uniprot id: I5B6Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

879212:DESPODRAFT RS02395
gene id: 879212:DESPODRAFT_RS02395
uniprot id: I5AZ18
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS16620
gene id: 879212:DESPODRAFT_RS16620
uniprot id: I5B6Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

879212:DESPODRAFT RS17195
gene id: 879212:DESPODRAFT_RS17195
uniprot id: I5B720
names: Similarity
messages: Belongs to the TlyA family.

879212:DESPODRAFT RS16035
gene id: 879212:DESPODRAFT_RS16035
uniprot id: I5B6E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

879212:DESPODRAFT RS05830
gene id: 879212:DESPODRAFT_RS05830
uniprot id: I5B0W9
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS17325
gene id: 879212:DESPODRAFT_RS17325
uniprot id: I5B744
names: Similarity
messages: Belongs to the PspA/IM30 family.

879212:DESPODRAFT RS05020
gene id: 879212:DESPODRAFT_RS05020
uniprot id: I5B0F8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

879212:DESPODRAFT RS06090
gene id: 879212:DESPODRAFT_RS06090
uniprot id: I5B121
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

879212:DESPODRAFT RS14815
gene id: 879212:DESPODRAFT_RS14815
uniprot id: I5B5R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

879212:DESPODRAFT RS04045
gene id: 879212:DESPODRAFT_RS04045
uniprot id: I5AZW7
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS10115
gene id: 879212:DESPODRAFT_RS10115
uniprot id: I5B376
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS12945
gene id: 879212:DESPODRAFT_RS12945
uniprot id: I5B4R4
names: Similarity
messages: Belongs to the histone deacetylase family.

879212:DESPODRAFT RS10800
gene id: 879212:DESPODRAFT_RS10800
uniprot id: I5B3K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

879212:DESPODRAFT RS00825
gene id: 879212:DESPODRAFT_RS00825
uniprot id: I5AY77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

879212:DESPODRAFT RS05555
gene id: 879212:DESPODRAFT_RS05555
uniprot id: I5B0R7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

879212:DESPODRAFT RS06840
gene id: 879212:DESPODRAFT_RS06840
uniprot id: I5B1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

879212:DESPODRAFT RS11375
gene id: 879212:DESPODRAFT_RS11375
uniprot id: I5B3W3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS11925
gene id: 879212:DESPODRAFT_RS11925
uniprot id: I5B465
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

879212:DESPODRAFT RS01660
gene id: 879212:DESPODRAFT_RS01660
uniprot id: I5AYN1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

879212:DESPODRAFT RS06110
gene id: 879212:DESPODRAFT_RS06110
uniprot id: I5B125
names: Similarity
messages: Belongs to the type IA topoisomerase family.

879212:DESPODRAFT RS04130
gene id: 879212:DESPODRAFT_RS04130
uniprot id: I5AZY4
names: Subunit
messages: Heterodimer of a large and a small subunit.

879212:DESPODRAFT RS18830
gene id: 879212:DESPODRAFT_RS18830
uniprot id: I5B6B8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

879212:DESPODRAFT RS12210
gene id: 879212:DESPODRAFT_RS12210
uniprot id: I5B4B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

879212:DESPODRAFT RS03600
gene id: 879212:DESPODRAFT_RS03600
uniprot id: I5AZN7
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

879212:DESPODRAFT RS11190
gene id: 879212:DESPODRAFT_RS11190
uniprot id: I5B3S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS18505
gene id: 879212:DESPODRAFT_RS18505
uniprot id: I5AYT7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

879212:DESPODRAFT RS02385
gene id: 879212:DESPODRAFT_RS02385
uniprot id: I5AZ16
names: Similarity
messages: Belongs to the acetokinase family.

879212:DESPODRAFT RS15790
gene id: 879212:DESPODRAFT_RS15790
uniprot id: I5B694
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

879212:DESPODRAFT RS07165
gene id: 879212:DESPODRAFT_RS07165
uniprot id: I5B1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

879212:DESPODRAFT RS08885
gene id: 879212:DESPODRAFT_RS08885
uniprot id: I5B2J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

879212:DESPODRAFT RS03315
gene id: 879212:DESPODRAFT_RS03315
uniprot id: I5AZJ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

879212:DESPODRAFT RS18775
gene id: 879212:DESPODRAFT_RS18775
uniprot id: I5B5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

879212:DESPODRAFT RS10950
gene id: 879212:DESPODRAFT_RS10950
uniprot id: I5B3N1
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

879212:DESPODRAFT RS01680
gene id: 879212:DESPODRAFT_RS01680
uniprot id: I5AYN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

879212:DESPODRAFT RS01340
gene id: 879212:DESPODRAFT_RS01340
uniprot id: I5AYH4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

879212:DESPODRAFT RS17310
gene id: 879212:DESPODRAFT_RS17310
uniprot id: I5B741
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

879212:DESPODRAFT RS18405
gene id: 879212:DESPODRAFT_RS18405
uniprot id: I5B7P1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS07830
gene id: 879212:DESPODRAFT_RS07830
uniprot id: I5B1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

879212:DESPODRAFT RS04570
gene id: 879212:DESPODRAFT_RS04570
uniprot id: I5B065
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

879212:DESPODRAFT RS14865
gene id: 879212:DESPODRAFT_RS14865
uniprot id: I5B5S2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

879212:DESPODRAFT RS01145
gene id: 879212:DESPODRAFT_RS01145
uniprot id: I5AYD7
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

879212:DESPODRAFT RS15510
gene id: 879212:DESPODRAFT_RS15510
uniprot id: I5B643
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

879212:DESPODRAFT RS02560
gene id: 879212:DESPODRAFT_RS02560
uniprot id: I5AZ49
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879212:DESPODRAFT RS11185
gene id: 879212:DESPODRAFT_RS11185
uniprot id: I5B3S6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS00760
gene id: 879212:DESPODRAFT_RS00760
uniprot id: I5AY65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

879212:DESPODRAFT RS11600
gene id: 879212:DESPODRAFT_RS11600
uniprot id: I5B410
names: Subunit
messages: Homodimer.

879212:DESPODRAFT RS12120
gene id: 879212:DESPODRAFT_RS12120
uniprot id: I5B499
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

879212:DESPODRAFT RS12275
gene id: 879212:DESPODRAFT_RS12275
uniprot id: I5B4D2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

879212:DESPODRAFT RS00890
gene id: 879212:DESPODRAFT_RS00890
uniprot id: I5AY91
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

879212:DESPODRAFT RS03170
gene id: 879212:DESPODRAFT_RS03170
uniprot id: I5AZG5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

879212:DESPODRAFT RS02575
gene id: 879212:DESPODRAFT_RS02575
uniprot id: I5AZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

879212:DESPODRAFT RS03200
gene id: 879212:DESPODRAFT_RS03200
uniprot id: I5AZG9
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS11540
gene id: 879212:DESPODRAFT_RS11540
uniprot id: I5B3Z7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS07625
gene id: 879212:DESPODRAFT_RS07625
uniprot id: I5B1W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

879212:DESPODRAFT RS14725
gene id: 879212:DESPODRAFT_RS14725
uniprot id: I5B5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

879212:DESPODRAFT RS10705
gene id: 879212:DESPODRAFT_RS10705
uniprot id: I5B3I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

879212:DESPODRAFT RS12230
gene id: 879212:DESPODRAFT_RS12230
uniprot id: I5B4C3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

879212:DESPODRAFT RS13585
gene id: 879212:DESPODRAFT_RS13585
uniprot id: I5B527
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

879212:DESPODRAFT RS15370
gene id: 879212:DESPODRAFT_RS15370
uniprot id: I5B618
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879212:DESPODRAFT RS01525
gene id: 879212:DESPODRAFT_RS01525
uniprot id: I5AYK5
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

879212:DESPODRAFT RS04500
gene id: 879212:DESPODRAFT_RS04500
uniprot id: I5B052
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879212:DESPODRAFT RS10760
gene id: 879212:DESPODRAFT_RS10760
uniprot id: I5B3J3
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS15935
gene id: 879212:DESPODRAFT_RS15935
uniprot id: I5B6C6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

879212:DESPODRAFT RS09175
gene id: 879212:DESPODRAFT_RS09175
uniprot id: I5B2P6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

879212:DESPODRAFT RS03510
gene id: 879212:DESPODRAFT_RS03510
uniprot id: I5AZM2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

879212:DESPODRAFT RS02980
gene id: 879212:DESPODRAFT_RS02980
uniprot id: I5AZD0
names: Subcellular Location Annotation
messages: Cytoplasm

879212:DESPODRAFT RS01440
gene id: 879212:DESPODRAFT_RS01440
uniprot id: I5AYJ0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

879212:DESPODRAFT RS16675
gene id: 879212:DESPODRAFT_RS16675
uniprot id: I5B6S0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

879212:DESPODRAFT RS01555
gene id: 879212:DESPODRAFT_RS01555
uniprot id: I5AYK9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

879212:DESPODRAFT RS07485
gene id: 879212:DESPODRAFT_RS07485
uniprot id: I5B1T3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

879212:DESPODRAFT RS02705
gene id: 879212:DESPODRAFT_RS02705
uniprot id: I5AZ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

879212:DESPODRAFT RS04435
gene id: 879212:DESPODRAFT_RS04435
uniprot id: I5B042
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

879212:DESPODRAFT RS03910
gene id: 879212:DESPODRAFT_RS03910
uniprot id: I5AZU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

879212:DESPODRAFT RS11200
gene id: 879212:DESPODRAFT_RS11200
uniprot id: I5B3S9
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS15910
gene id: 879212:DESPODRAFT_RS15910
uniprot id: I5B6C1
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS06665
gene id: 879212:DESPODRAFT_RS06665
uniprot id: I5B1D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

879212:DESPODRAFT RS16525
gene id: 879212:DESPODRAFT_RS16525
uniprot id: I5B6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

879212:DESPODRAFT RS09575
gene id: 879212:DESPODRAFT_RS09575
uniprot id: I5B2X4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

879212:DESPODRAFT RS11225
gene id: 879212:DESPODRAFT_RS11225
uniprot id: I5B3T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

879212:DESPODRAFT RS10635
gene id: 879212:DESPODRAFT_RS10635
uniprot id: I5B3H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS01000
gene id: 879212:DESPODRAFT_RS01000
uniprot id: I5AYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS07755
gene id: 879212:DESPODRAFT_RS07755
uniprot id: I5B1Y1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

879212:DESPODRAFT RS03975
gene id: 879212:DESPODRAFT_RS03975
uniprot id: I5AZV4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879212:DESPODRAFT RS01280
gene id: 879212:DESPODRAFT_RS01280
uniprot id: I5AYG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

879212:DESPODRAFT RS17580
gene id: 879212:DESPODRAFT_RS17580
uniprot id: I5B792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS17625
gene id: 879212:DESPODRAFT_RS17625
uniprot id: I5B7A1
names: Similarity
messages: Belongs to the universal stress protein A family.

879212:DESPODRAFT RS03015
gene id: 879212:DESPODRAFT_RS03015
uniprot id: I5AZD6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

879212:DESPODRAFT RS07920
gene id: 879212:DESPODRAFT_RS07920
uniprot id: I5B212
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

879212:DESPODRAFT RS11425
gene id: 879212:DESPODRAFT_RS11425
uniprot id: I5B3X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

879212:DESPODRAFT RS06470
gene id: 879212:DESPODRAFT_RS06470
uniprot id: I5B194
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

879212:DESPODRAFT RS02840
gene id: 879212:DESPODRAFT_RS02840
uniprot id: I5AZA4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

879212:DESPODRAFT RS14205
gene id: 879212:DESPODRAFT_RS14205
uniprot id: I5B5E5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

879212:DESPODRAFT RS11820
gene id: 879212:DESPODRAFT_RS11820
uniprot id: I5B448
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS09900
gene id: 879212:DESPODRAFT_RS09900
uniprot id: I5B335
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

879212:DESPODRAFT RS13845
gene id: 879212:DESPODRAFT_RS13845
uniprot id: I5B575
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

879212:DESPODRAFT RS01740
gene id: 879212:DESPODRAFT_RS01740
uniprot id: I5AYP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

879212:DESPODRAFT RS04665
gene id: 879212:DESPODRAFT_RS04665
uniprot id: I5B084
names: Similarity
messages: Belongs to the CFA/CMAS family.

879212:DESPODRAFT RS00810
gene id: 879212:DESPODRAFT_RS00810
uniprot id: I5AY74
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

879212:DESPODRAFT RS08845
gene id: 879212:DESPODRAFT_RS08845
uniprot id: I5B2I7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

879212:DESPODRAFT RS06945
gene id: 879212:DESPODRAFT_RS06945
uniprot id: I5B1I3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

879212:DESPODRAFT RS02285
gene id: 879212:DESPODRAFT_RS02285
uniprot id: I5AYZ7
names: Similarity
messages: Belongs to the peptidase S41A family.

879212:DESPODRAFT RS15900
gene id: 879212:DESPODRAFT_RS15900
uniprot id: I5B6B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

879212:DESPODRAFT RS14130
gene id: 879212:DESPODRAFT_RS14130
uniprot id: I5B5D2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

879212:DESPODRAFT RS09150
gene id: 879212:DESPODRAFT_RS09150
uniprot id: I5B2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

879212:DESPODRAFT RS07480
gene id: 879212:DESPODRAFT_RS07480
uniprot id: I5B1T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

879212:DESPODRAFT RS10180
gene id: 879212:DESPODRAFT_RS10180
uniprot id: I5B386
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Belongs to the GARS family.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

879212:DESPODRAFT RS07855
gene id: 879212:DESPODRAFT_RS07855
uniprot id: I5B200
names: Similarity
messages: Belongs to the universal stress protein A family.

879212:DESPODRAFT RS10240
gene id: 879212:DESPODRAFT_RS10240
uniprot id: I5B396
names: Similarity
messages: Belongs to the ABC transporter superfamily.

879212:DESPODRAFT RS14565
gene id: 879212:DESPODRAFT_RS14565
uniprot id: I5B5L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

879212:DESPODRAFT RS06935
gene id: 879212:DESPODRAFT_RS06935
uniprot id: I5B1I1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

879212:DESPODRAFT RS02800
gene id: 879212:DESPODRAFT_RS02800
uniprot id: I5AZ96
names: Subcellular Location Annotation
messages: Periplasm

879212:DESPODRAFT RS11370
gene id: 879212:DESPODRAFT_RS11370
uniprot id: I5B3W2
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS12125
gene id: 879212:DESPODRAFT_RS12125
uniprot id: I5B4A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

879212:DESPODRAFT RS03195
gene id: 879212:DESPODRAFT_RS03195
uniprot id: I5AZG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

879212:DESPODRAFT RS11230
gene id: 879212:DESPODRAFT_RS11230
uniprot id: I5B3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

879212:DESPODRAFT RS13355
gene id: 879212:DESPODRAFT_RS13355
uniprot id: I5B4Z0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

879212:DESPODRAFT RS06605
gene id: 879212:DESPODRAFT_RS06605
uniprot id: I5B1B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

879212:DESPODRAFT RS04675
gene id: 879212:DESPODRAFT_RS04675
uniprot id: I5B086
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

879212:DESPODRAFT RS16765
gene id: 879212:DESPODRAFT_RS16765
uniprot id: I5B6T6
names: Similarity
names: Subunit
messages: Belongs to the CmpA/NrtA family.
messages: Heterodimer of a large and a small subunit.

879212:DESPODRAFT RS11170
gene id: 879212:DESPODRAFT_RS11170
uniprot id: I5B3S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

879212:DESPODRAFT RS16670
gene id: 879212:DESPODRAFT_RS16670
uniprot id: I5B6R9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

879212:DESPODRAFT RS02615
gene id: 879212:DESPODRAFT_RS02615
uniprot id: I5AZ60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

879212:DESPODRAFT RS02030
gene id: 879212:DESPODRAFT_RS02030
uniprot id: I5AYU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

879212:DESPODRAFT RS12710
gene id: 879212:DESPODRAFT_RS12710
uniprot id: I5B4L8
names: Similarity
messages: Belongs to the GSP E family.

879212:DESPODRAFT RS01360
gene id: 879212:DESPODRAFT_RS01360
uniprot id: I5AYH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS09725
gene id: 879212:DESPODRAFT_RS09725
uniprot id: I5B302
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

879212:DESPODRAFT RS08840
gene id: 879212:DESPODRAFT_RS08840
uniprot id: I5B2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

879212:DESPODRAFT RS01695
gene id: 879212:DESPODRAFT_RS01695
uniprot id: I5AYN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

879212:DESPODRAFT RS17640
gene id: 879212:DESPODRAFT_RS17640
uniprot id: I5B7A4
names: Similarity
messages: Belongs to the CvfB family.

879212:DESPODRAFT RS14290
gene id: 879212:DESPODRAFT_RS14290
uniprot id: I5B5G2
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

879212:DESPODRAFT RS13275
gene id: 879212:DESPODRAFT_RS13275
uniprot id: I5B4X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

879212:DESPODRAFT RS15470
gene id: 879212:DESPODRAFT_RS15470
uniprot id: I5B635
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

879212:DESPODRAFT RS07945
gene id: 879212:DESPODRAFT_RS07945
uniprot id: I5B217
names: Similarity
messages: Belongs to the universal stress protein A family.

879212:DESPODRAFT RS05615
gene id: 879212:DESPODRAFT_RS05615
uniprot id: I5B0S7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

879212:DESPODRAFT RS02320
gene id: 879212:DESPODRAFT_RS02320
uniprot id: I5AZ04
names: Similarity
messages: Belongs to the P(II) protein family.

879212:DESPODRAFT RS04100
gene id: 879212:DESPODRAFT_RS04100
uniprot id: I5AZX8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

879212:DESPODRAFT RS16115
gene id: 879212:DESPODRAFT_RS16115
uniprot id: I5B6G1
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS13570
gene id: 879212:DESPODRAFT_RS13570
uniprot id: I5B524
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

879212:DESPODRAFT RS00755
gene id: 879212:DESPODRAFT_RS00755
uniprot id: I5AY64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

879212:DESPODRAFT RS07510
gene id: 879212:DESPODRAFT_RS07510
uniprot id: I5B1T8
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS13145
gene id: 879212:DESPODRAFT_RS13145
uniprot id: I5B4U8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS12080
gene id: 879212:DESPODRAFT_RS12080
uniprot id: I5B491
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

879212:DESPODRAFT RS02745
gene id: 879212:DESPODRAFT_RS02745
uniprot id: I5AZ85
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

879212:DESPODRAFT RS11570
gene id: 879212:DESPODRAFT_RS11570
uniprot id: I5B403
names: Similarity
names: Subunit
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.
messages: Monomer.

879212:DESPODRAFT RS00830
gene id: 879212:DESPODRAFT_RS00830
uniprot id: I5AY78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

879212:DESPODRAFT RS07965
gene id: 879212:DESPODRAFT_RS07965
uniprot id: I5B221
names: Similarity
messages: Belongs to the DprA/Smf family.

879212:DESPODRAFT RS00685
gene id: 879212:DESPODRAFT_RS00685
uniprot id: I5AY50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

879212:DESPODRAFT RS09195
gene id: 879212:DESPODRAFT_RS09195
uniprot id: I5B2Q0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

879212:DESPODRAFT RS12510
gene id: 879212:DESPODRAFT_RS12510
uniprot id: I5B4H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS01690
gene id: 879212:DESPODRAFT_RS01690
uniprot id: I5AYN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

879212:DESPODRAFT RS01730
gene id: 879212:DESPODRAFT_RS01730
uniprot id: I5AYP5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

879212:DESPODRAFT RS11335
gene id: 879212:DESPODRAFT_RS11335
uniprot id: I5B3V5
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

879212:DESPODRAFT RS15375
gene id: 879212:DESPODRAFT_RS15375
uniprot id: I5B619
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879212:DESPODRAFT RS08335
gene id: 879212:DESPODRAFT_RS08335
uniprot id: I5B288
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

879212:DESPODRAFT RS13320
gene id: 879212:DESPODRAFT_RS13320
uniprot id: I5B4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TolB family.
messages: Periplasm

879212:DESPODRAFT RS11235
gene id: 879212:DESPODRAFT_RS11235
uniprot id: I5B3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

879212:DESPODRAFT RS09520
gene id: 879212:DESPODRAFT_RS09520
uniprot id: I5B2W3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

879212:DESPODRAFT RS15120
gene id: 879212:DESPODRAFT_RS15120
uniprot id: I5B5X0
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

879212:DESPODRAFT RS11615
gene id: 879212:DESPODRAFT_RS11615
uniprot id: I5B413
names: Similarity
messages: Belongs to the MotB family.

879212:DESPODRAFT RS12285
gene id: 879212:DESPODRAFT_RS12285
uniprot id: I5B4D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

879212:DESPODRAFT RS12215
gene id: 879212:DESPODRAFT_RS12215
uniprot id: I5B4C0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

879212:DESPODRAFT RS00425
gene id: 879212:DESPODRAFT_RS00425
uniprot id: I5AY00
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

879212:DESPODRAFT RS07050
gene id: 879212:DESPODRAFT_RS07050
uniprot id: I5B1K3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879212:DESPODRAFT RS09695
gene id: 879212:DESPODRAFT_RS09695
uniprot id: I5B2Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

879212:DESPODRAFT RS09610
gene id: 879212:DESPODRAFT_RS09610
uniprot id: I5B2Y1
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

879212:DESPODRAFT RS09040
gene id: 879212:DESPODRAFT_RS09040
uniprot id: I5B2M3
names: Similarity
messages: Belongs to the CinA family.

879212:DESPODRAFT RS00815
gene id: 879212:DESPODRAFT_RS00815
uniprot id: I5AY75
names: Similarity
messages: Belongs to the HypD family.

879212:DESPODRAFT RS13010
gene id: 879212:DESPODRAFT_RS13010
uniprot id: I5B4S7
names: Similarity
messages: Belongs to the thioesterase PaaI family.

879212:DESPODRAFT RS01600
gene id: 879212:DESPODRAFT_RS01600
uniprot id: I5AYL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

879212:DESPODRAFT RS13635
gene id: 879212:DESPODRAFT_RS13635
uniprot id: I5B537
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

879212:DESPODRAFT RS04165
gene id: 879212:DESPODRAFT_RS04165
uniprot id: I5AZZ1
names: Similarity
messages: Belongs to the IMPACT family.

879212:DESPODRAFT RS09995
gene id: 879212:DESPODRAFT_RS09995
uniprot id: I5B353
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS03120
gene id: 879212:DESPODRAFT_RS03120
uniprot id: I5AZF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

879212:DESPODRAFT RS02805
gene id: 879212:DESPODRAFT_RS02805
uniprot id: I5AZ97
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

879212:DESPODRAFT RS04210
gene id: 879212:DESPODRAFT_RS04210
uniprot id: I5B000
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS02315
gene id: 879212:DESPODRAFT_RS02315
uniprot id: I5AZ03
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

879212:DESPODRAFT RS05720
gene id: 879212:DESPODRAFT_RS05720
uniprot id: I5B0U8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

879212:DESPODRAFT RS04360
gene id: 879212:DESPODRAFT_RS04360
uniprot id: I5B028
names: Similarity
messages: Belongs to the glutamate synthase family.

879212:DESPODRAFT RS13350
gene id: 879212:DESPODRAFT_RS13350
uniprot id: I5B4Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

879212:DESPODRAFT RS08490
gene id: 879212:DESPODRAFT_RS08490
uniprot id: I5B2B9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

879212:DESPODRAFT RS07045
gene id: 879212:DESPODRAFT_RS07045
uniprot id: I5B1K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

879212:DESPODRAFT RS14150
gene id: 879212:DESPODRAFT_RS14150
uniprot id: I5B5D6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

879212:DESPODRAFT RS00660
gene id: 879212:DESPODRAFT_RS00660
uniprot id: I5AY45
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

879212:DESPODRAFT RS02050
gene id: 879212:DESPODRAFT_RS02050
uniprot id: I5AYV3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

879212:DESPODRAFT RS15205
gene id: 879212:DESPODRAFT_RS15205
uniprot id: I5B5Y6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

879212:DESPODRAFT RS05025
gene id: 879212:DESPODRAFT_RS05025
uniprot id: I5B0F9
names: Function
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).

879212:DESPODRAFT RS15135
gene id: 879212:DESPODRAFT_RS15135
uniprot id: I5B5X3
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

879212:DESPODRAFT RS01320
gene id: 879212:DESPODRAFT_RS01320
uniprot id: I5AYH0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

879212:DESPODRAFT RS17555
gene id: 879212:DESPODRAFT_RS17555
uniprot id: I5B787
names: Similarity
messages: Belongs to the Ahb/Nir family.

879212:DESPODRAFT RS07630
gene id: 879212:DESPODRAFT_RS07630
uniprot id: I5B1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

879212:DESPODRAFT RS12475
gene id: 879212:DESPODRAFT_RS12475
uniprot id: I5B4H1
names: Similarity
messages: Belongs to the FlgM family.

879212:DESPODRAFT RS17265
gene id: 879212:DESPODRAFT_RS17265
uniprot id: I5B733
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

879212:DESPODRAFT RS15220
gene id: 879212:DESPODRAFT_RS15220
uniprot id: I5B5Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

879212:DESPODRAFT RS12830
gene id: 879212:DESPODRAFT_RS12830
uniprot id: I5B4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

879212:DESPODRAFT RS14505
gene id: 879212:DESPODRAFT_RS14505
uniprot id: I5B5K5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

879212:DESPODRAFT RS06465
gene id: 879212:DESPODRAFT_RS06465
uniprot id: I5B193
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS21165
gene id: 879212:DESPODRAFT_RS21165
uniprot id: I5B5N2
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS02325
gene id: 879212:DESPODRAFT_RS02325
uniprot id: I5AZ05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

879212:DESPODRAFT RS06740
gene id: 879212:DESPODRAFT_RS06740
uniprot id: I5B1E3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

879212:DESPODRAFT RS09835
gene id: 879212:DESPODRAFT_RS09835
uniprot id: I5B322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS09985
gene id: 879212:DESPODRAFT_RS09985
uniprot id: I5B351
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879212:DESPODRAFT RS10660
gene id: 879212:DESPODRAFT_RS10660
uniprot id: I5B3H4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

879212:DESPODRAFT RS14070
gene id: 879212:DESPODRAFT_RS14070
uniprot id: I5B5B9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS12305
gene id: 879212:DESPODRAFT_RS12305
uniprot id: I5B4D8
names: Similarity
messages: Belongs to the aspartokinase family.

879212:DESPODRAFT RS01285
gene id: 879212:DESPODRAFT_RS01285
uniprot id: I5AYG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

879212:DESPODRAFT RS14050
gene id: 879212:DESPODRAFT_RS14050
uniprot id: I5B5B5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

879212:DESPODRAFT RS07195
gene id: 879212:DESPODRAFT_RS07195
uniprot id: I5B1M9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

879212:DESPODRAFT RS09690
gene id: 879212:DESPODRAFT_RS09690
uniprot id: I5B2Z5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

879212:DESPODRAFT RS03525
gene id: 879212:DESPODRAFT_RS03525
uniprot id: I5AZM4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

879212:DESPODRAFT RS08785
gene id: 879212:DESPODRAFT_RS08785
uniprot id: I5B2H5
names: Similarity
messages: Belongs to the CFA/CMAS family.

879212:DESPODRAFT RS02700
gene id: 879212:DESPODRAFT_RS02700
uniprot id: I5AZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

879212:DESPODRAFT RS17785
gene id: 879212:DESPODRAFT_RS17785
uniprot id: I5B7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

879212:DESPODRAFT RS13605
gene id: 879212:DESPODRAFT_RS13605
uniprot id: I5B531
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

879212:DESPODRAFT RS09010
gene id: 879212:DESPODRAFT_RS09010
uniprot id: I5B2L5
names: Similarity
messages: Belongs to the TrpF family.

879212:DESPODRAFT RS04505
gene id: 879212:DESPODRAFT_RS04505
uniprot id: I5B053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS16955
gene id: 879212:DESPODRAFT_RS16955
uniprot id: I5B6X3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

879212:DESPODRAFT RS07040
gene id: 879212:DESPODRAFT_RS07040
uniprot id: I5B1K1
names: Similarity
messages: Belongs to the Ahb/Nir family.

879212:DESPODRAFT RS14145
gene id: 879212:DESPODRAFT_RS14145
uniprot id: I5B5D5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

879212:DESPODRAFT RS03270
gene id: 879212:DESPODRAFT_RS03270
uniprot id: I5AZI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

879212:DESPODRAFT RS12135
gene id: 879212:DESPODRAFT_RS12135
uniprot id: I5B4A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

879212:DESPODRAFT RS12685
gene id: 879212:DESPODRAFT_RS12685
uniprot id: I5B4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

879212:DESPODRAFT RS15680
gene id: 879212:DESPODRAFT_RS15680
uniprot id: I5B675
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

879212:DESPODRAFT RS17060
gene id: 879212:DESPODRAFT_RS17060
uniprot id: I5B6Z3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

879212:DESPODRAFT RS16985
gene id: 879212:DESPODRAFT_RS16985
uniprot id: I5B6X9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

879212:DESPODRAFT RS12195
gene id: 879212:DESPODRAFT_RS12195
uniprot id: I5B4B5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

879212:DESPODRAFT RS01560
gene id: 879212:DESPODRAFT_RS01560
uniprot id: I5AYL0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

879212:DESPODRAFT RS08865
gene id: 879212:DESPODRAFT_RS08865
uniprot id: I5B2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

879212:DESPODRAFT RS15325
gene id: 879212:DESPODRAFT_RS15325
uniprot id: I5B609
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

879212:DESPODRAFT RS16575
gene id: 879212:DESPODRAFT_RS16575
uniprot id: I5B6Q0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

879212:DESPODRAFT RS13410
gene id: 879212:DESPODRAFT_RS13410
uniprot id: I5B501
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

879212:DESPODRAFT RS12935
gene id: 879212:DESPODRAFT_RS12935
uniprot id: I5B4R2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

879212:DESPODRAFT RS14110
gene id: 879212:DESPODRAFT_RS14110
uniprot id: I5B5C8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

879212:DESPODRAFT RS07795
gene id: 879212:DESPODRAFT_RS07795
uniprot id: I5B1Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

879212:DESPODRAFT RS14900
gene id: 879212:DESPODRAFT_RS14900
uniprot id: I5B5S9
names: Similarity
messages: Belongs to the oxoprolinase family.

879212:DESPODRAFT RS13335
gene id: 879212:DESPODRAFT_RS13335
uniprot id: I5B4Y6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

879212:DESPODRAFT RS03415
gene id: 879212:DESPODRAFT_RS03415
uniprot id: I5AZK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

879212:DESPODRAFT RS10700
gene id: 879212:DESPODRAFT_RS10700
uniprot id: I5B3I1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

879212:DESPODRAFT RS00310
gene id: 879212:DESPODRAFT_RS00310
uniprot id: I5AXY2
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

879212:DESPODRAFT RS03465
gene id: 879212:DESPODRAFT_RS03465
uniprot id: I5AZL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS15930
gene id: 879212:DESPODRAFT_RS15930
uniprot id: I5B6C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

879212:DESPODRAFT RS16475
gene id: 879212:DESPODRAFT_RS16475
uniprot id: I5B6M9
names: Similarity
messages: Belongs to the group II decarboxylase family.

879212:DESPODRAFT RS05120
gene id: 879212:DESPODRAFT_RS05120
uniprot id: I5B0I0
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

879212:DESPODRAFT RS09615
gene id: 879212:DESPODRAFT_RS09615
uniprot id: I5B2Y2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

879212:DESPODRAFT RS00295
gene id: 879212:DESPODRAFT_RS00295
uniprot id: I5AXX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS12315
gene id: 879212:DESPODRAFT_RS12315
uniprot id: I5B4E0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

879212:DESPODRAFT RS08540
gene id: 879212:DESPODRAFT_RS08540
uniprot id: I5B2C9
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS05590
gene id: 879212:DESPODRAFT_RS05590
uniprot id: I5B0S3
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS13405
gene id: 879212:DESPODRAFT_RS13405
uniprot id: I5B500
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

879212:DESPODRAFT RS07535
gene id: 879212:DESPODRAFT_RS07535
uniprot id: I5B1U3
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS06655
gene id: 879212:DESPODRAFT_RS06655
uniprot id: I5B1C8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

879212:DESPODRAFT RS04030
gene id: 879212:DESPODRAFT_RS04030
uniprot id: I5AZW4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

879212:DESPODRAFT RS11105
gene id: 879212:DESPODRAFT_RS11105
uniprot id: I5B3R0
names: Similarity
messages: Belongs to the UPF0047 family.

879212:DESPODRAFT RS12140
gene id: 879212:DESPODRAFT_RS12140
uniprot id: I5B4A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

879212:DESPODRAFT RS01150
gene id: 879212:DESPODRAFT_RS01150
uniprot id: I5AYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS05350
gene id: 879212:DESPODRAFT_RS05350
uniprot id: I5B0M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

879212:DESPODRAFT RS03400
gene id: 879212:DESPODRAFT_RS03400
uniprot id: I5AZK5
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

879212:DESPODRAFT RS02670
gene id: 879212:DESPODRAFT_RS02670
uniprot id: I5AZ71
names: Similarity
messages: Belongs to the TrpF family.

879212:DESPODRAFT RS14115
gene id: 879212:DESPODRAFT_RS14115
uniprot id: I5B5C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS09205
gene id: 879212:DESPODRAFT_RS09205
uniprot id: I5B2Q2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

879212:DESPODRAFT RS03115
gene id: 879212:DESPODRAFT_RS03115
uniprot id: I5AZF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

879212:DESPODRAFT RS08035
gene id: 879212:DESPODRAFT_RS08035
uniprot id: I5B235
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

879212:DESPODRAFT RS10255
gene id: 879212:DESPODRAFT_RS10255
uniprot id: I5B399
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS11350
gene id: 879212:DESPODRAFT_RS11350
uniprot id: I5B3V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

879212:DESPODRAFT RS10715
gene id: 879212:DESPODRAFT_RS10715
uniprot id: I5B3I3
names: Similarity
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.

879212:DESPODRAFT RS01190
gene id: 879212:DESPODRAFT_RS01190
uniprot id: I5AYE6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

879212:DESPODRAFT RS17845
gene id: 879212:DESPODRAFT_RS17845
uniprot id: I5B7D5
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS13480
gene id: 879212:DESPODRAFT_RS13480
uniprot id: I5B515
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

879212:DESPODRAFT RS14555
gene id: 879212:DESPODRAFT_RS14555
uniprot id: I5B5L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

879212:DESPODRAFT RS11300
gene id: 879212:DESPODRAFT_RS11300
uniprot id: I5B3U9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

879212:DESPODRAFT RS07470
gene id: 879212:DESPODRAFT_RS07470
uniprot id: I5B1T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

879212:DESPODRAFT RS15875
gene id: 879212:DESPODRAFT_RS15875
uniprot id: I5B6B4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

879212:DESPODRAFT RS13670
gene id: 879212:DESPODRAFT_RS13670
uniprot id: I5B544
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

879212:DESPODRAFT RS05690
gene id: 879212:DESPODRAFT_RS05690
uniprot id: I5B0U2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS07670
gene id: 879212:DESPODRAFT_RS07670
uniprot id: I5B1X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

879212:DESPODRAFT RS18385
gene id: 879212:DESPODRAFT_RS18385
uniprot id: I5B7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

879212:DESPODRAFT RS21065
gene id: 879212:DESPODRAFT_RS21065
uniprot id: I5B392
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS02175
gene id: 879212:DESPODRAFT_RS02175
uniprot id: I5AYX7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

879212:DESPODRAFT RS05445
gene id: 879212:DESPODRAFT_RS05445
uniprot id: I5B0P6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

879212:DESPODRAFT RS05700
gene id: 879212:DESPODRAFT_RS05700
uniprot id: I5B0U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

879212:DESPODRAFT RS03060
gene id: 879212:DESPODRAFT_RS03060
uniprot id: I5AZE5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

879212:DESPODRAFT RS03365
gene id: 879212:DESPODRAFT_RS03365
uniprot id: I5AZJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

879212:DESPODRAFT RS06135
gene id: 879212:DESPODRAFT_RS06135
uniprot id: I5B130
names: Similarity
messages: Belongs to the GSP E family.

879212:DESPODRAFT RS05710
gene id: 879212:DESPODRAFT_RS05710
uniprot id: I5B0U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

879212:DESPODRAFT RS05550
gene id: 879212:DESPODRAFT_RS05550
uniprot id: I5B0R6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

879212:DESPODRAFT RS06910
gene id: 879212:DESPODRAFT_RS06910
uniprot id: I5B1H6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

879212:DESPODRAFT RS08350
gene id: 879212:DESPODRAFT_RS08350
uniprot id: I5B291
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS04495
gene id: 879212:DESPODRAFT_RS04495
uniprot id: I5B051
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS12095
gene id: 879212:DESPODRAFT_RS12095
uniprot id: I5B494
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

879212:DESPODRAFT RS15125
gene id: 879212:DESPODRAFT_RS15125
uniprot id: I5B5X1
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

879212:DESPODRAFT RS17340
gene id: 879212:DESPODRAFT_RS17340
uniprot id: I5B747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

879212:DESPODRAFT RS01645
gene id: 879212:DESPODRAFT_RS01645
uniprot id: I5AYM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

879212:DESPODRAFT RS11855
gene id: 879212:DESPODRAFT_RS11855
uniprot id: I5B455
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS14560
gene id: 879212:DESPODRAFT_RS14560
uniprot id: I5B5L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

879212:DESPODRAFT RS08440
gene id: 879212:DESPODRAFT_RS08440
uniprot id: I5B2A9
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS10850
gene id: 879212:DESPODRAFT_RS10850
uniprot id: I5B3L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

879212:DESPODRAFT RS12780
gene id: 879212:DESPODRAFT_RS12780
uniprot id: I5B4N2
names: Cofactor
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

879212:DESPODRAFT RS09620
gene id: 879212:DESPODRAFT_RS09620
uniprot id: I5B2Y3
names: Similarity
messages: Belongs to the UPF0270 family.

879212:DESPODRAFT RS17875
gene id: 879212:DESPODRAFT_RS17875
uniprot id: I5B7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

879212:DESPODRAFT RS04440
gene id: 879212:DESPODRAFT_RS04440
uniprot id: I5B043
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

879212:DESPODRAFT RS05525
gene id: 879212:DESPODRAFT_RS05525
uniprot id: I5B0R1
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

879212:DESPODRAFT RS11205
gene id: 879212:DESPODRAFT_RS11205
uniprot id: I5B3T0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS10235
gene id: 879212:DESPODRAFT_RS10235
uniprot id: I5B395
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

879212:DESPODRAFT RS16615
gene id: 879212:DESPODRAFT_RS16615
uniprot id: I5B6Q8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

879212:DESPODRAFT RS07860
gene id: 879212:DESPODRAFT_RS07860
uniprot id: I5B201
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

879212:DESPODRAFT RS02185
gene id: 879212:DESPODRAFT_RS02185
uniprot id: I5AYX9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

879212:DESPODRAFT RS07615
gene id: 879212:DESPODRAFT_RS07615
uniprot id: I5B1V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

879212:DESPODRAFT RS01720
gene id: 879212:DESPODRAFT_RS01720
uniprot id: I5AYP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS11330
gene id: 879212:DESPODRAFT_RS11330
uniprot id: I5B3V4
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS10630
gene id: 879212:DESPODRAFT_RS10630
uniprot id: I5B3G9
names: Similarity
messages: Belongs to the P(II) protein family.

879212:DESPODRAFT RS08005
gene id: 879212:DESPODRAFT_RS08005
uniprot id: I5B229
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

879212:DESPODRAFT RS10740
gene id: 879212:DESPODRAFT_RS10740
uniprot id: I5B3I8
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS18420
gene id: 879212:DESPODRAFT_RS18420
uniprot id: I5B7P4
names: Similarity
messages: Belongs to the universal stress protein A family.

879212:DESPODRAFT RS03165
gene id: 879212:DESPODRAFT_RS03165
uniprot id: I5AZG4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

879212:DESPODRAFT RS08340
gene id: 879212:DESPODRAFT_RS08340
uniprot id: I5B289
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

879212:DESPODRAFT RS09200
gene id: 879212:DESPODRAFT_RS09200
uniprot id: I5B2Q1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

879212:DESPODRAFT RS11490
gene id: 879212:DESPODRAFT_RS11490
uniprot id: I5B3Y6
names: Similarity
messages: Belongs to the RemA family.

879212:DESPODRAFT RS11215
gene id: 879212:DESPODRAFT_RS11215
uniprot id: I5B3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

879212:DESPODRAFT RS05715
gene id: 879212:DESPODRAFT_RS05715
uniprot id: I5B0U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

879212:DESPODRAFT RS00970
gene id: 879212:DESPODRAFT_RS00970
uniprot id: I5AYA7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

879212:DESPODRAFT RS06195
gene id: 879212:DESPODRAFT_RS06195
uniprot id: I5B142
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

879212:DESPODRAFT RS12060
gene id: 879212:DESPODRAFT_RS12060
uniprot id: I5B487
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

879212:DESPODRAFT RS10670
gene id: 879212:DESPODRAFT_RS10670
uniprot id: I5B3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

879212:DESPODRAFT RS10925
gene id: 879212:DESPODRAFT_RS10925
uniprot id: I5B3M6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

879212:DESPODRAFT RS05420
gene id: 879212:DESPODRAFT_RS05420
uniprot id: I5B0P1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

879212:DESPODRAFT RS02710
gene id: 879212:DESPODRAFT_RS02710
uniprot id: I5AZ79
names: Similarity
messages: Belongs to the catalase family.

879212:DESPODRAFT RS02900
gene id: 879212:DESPODRAFT_RS02900
uniprot id: I5AZB6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

879212:DESPODRAFT RS14790
gene id: 879212:DESPODRAFT_RS14790
uniprot id: I5B5Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

879212:DESPODRAFT RS09260
gene id: 879212:DESPODRAFT_RS09260
uniprot id: I5B2R4
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS12200
gene id: 879212:DESPODRAFT_RS12200
uniprot id: I5B4B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

879212:DESPODRAFT RS07715
gene id: 879212:DESPODRAFT_RS07715
uniprot id: I5B1X3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

879212:DESPODRAFT RS13650
gene id: 879212:DESPODRAFT_RS13650
uniprot id: I5B540
names: Cofactor
messages: Binds 1 FAD per subunit.

879212:DESPODRAFT RS09145
gene id: 879212:DESPODRAFT_RS09145
uniprot id: I5B2P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

879212:DESPODRAFT RS11675
gene id: 879212:DESPODRAFT_RS11675
uniprot id: I5B420
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

879212:DESPODRAFT RS14280
gene id: 879212:DESPODRAFT_RS14280
uniprot id: I5B5G0
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS16350
gene id: 879212:DESPODRAFT_RS16350
uniprot id: I5B6K9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

879212:DESPODRAFT RS16640
gene id: 879212:DESPODRAFT_RS16640
uniprot id: I5B6R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS14235
gene id: 879212:DESPODRAFT_RS14235
uniprot id: I5B5F1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

879212:DESPODRAFT RS02850
gene id: 879212:DESPODRAFT_RS02850
uniprot id: I5AZA6
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

879212:DESPODRAFT RS06900
gene id: 879212:DESPODRAFT_RS06900
uniprot id: I5B1H4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

879212:DESPODRAFT RS16980
gene id: 879212:DESPODRAFT_RS16980
uniprot id: I5B6X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS14120
gene id: 879212:DESPODRAFT_RS14120
uniprot id: I5B5D0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

879212:DESPODRAFT RS04320
gene id: 879212:DESPODRAFT_RS04320
uniprot id: I5B020
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

879212:DESPODRAFT RS03905
gene id: 879212:DESPODRAFT_RS03905
uniprot id: I5AZU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

879212:DESPODRAFT RS12855
gene id: 879212:DESPODRAFT_RS12855
uniprot id: I5B4P6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

879212:DESPODRAFT RS10515
gene id: 879212:DESPODRAFT_RS10515
uniprot id: I5B3E9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

879212:DESPODRAFT RS04560
gene id: 879212:DESPODRAFT_RS04560
uniprot id: I5B063
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

879212:DESPODRAFT RS03300
gene id: 879212:DESPODRAFT_RS03300
uniprot id: I5AZI6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS00705
gene id: 879212:DESPODRAFT_RS00705
uniprot id: I5AY54
names: Similarity
messages: Belongs to the UPF0251 family.

879212:DESPODRAFT RS06550
gene id: 879212:DESPODRAFT_RS06550
uniprot id: I5B1B0
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS09055
gene id: 879212:DESPODRAFT_RS09055
uniprot id: I5B2M6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

879212:DESPODRAFT RS02490
gene id: 879212:DESPODRAFT_RS02490
uniprot id: I5AZ37
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

879212:DESPODRAFT RS10690
gene id: 879212:DESPODRAFT_RS10690
uniprot id: I5B3H9
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

879212:DESPODRAFT RS17070
gene id: 879212:DESPODRAFT_RS17070
uniprot id: I5B6Z5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

879212:DESPODRAFT RS12350
gene id: 879212:DESPODRAFT_RS12350
uniprot id: I5B4E7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879212:DESPODRAFT RS07545
gene id: 879212:DESPODRAFT_RS07545
uniprot id: I5B1U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

879212:DESPODRAFT RS13600
gene id: 879212:DESPODRAFT_RS13600
uniprot id: I5B530
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

879212:DESPODRAFT RS16045
gene id: 879212:DESPODRAFT_RS16045
uniprot id: I5B6E7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

879212:DESPODRAFT RS10860
gene id: 879212:DESPODRAFT_RS10860
uniprot id: I5B3L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

879212:DESPODRAFT RS02480
gene id: 879212:DESPODRAFT_RS02480
uniprot id: I5AZ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

879212:DESPODRAFT RS13090
gene id: 879212:DESPODRAFT_RS13090
uniprot id: I5B4U0
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

879212:DESPODRAFT RS15485
gene id: 879212:DESPODRAFT_RS15485
uniprot id: I5B638
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

879212:DESPODRAFT RS13980
gene id: 879212:DESPODRAFT_RS13980
uniprot id: I5B5A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

879212:DESPODRAFT RS09870
gene id: 879212:DESPODRAFT_RS09870
uniprot id: I5B329
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879212:DESPODRAFT RS05070
gene id: 879212:DESPODRAFT_RS05070
uniprot id: I5B0G8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS01930
gene id: 879212:DESPODRAFT_RS01930
uniprot id: I5AYT3
names: Similarity
messages: Belongs to the Nth/MutY family.

879212:DESPODRAFT RS05475
gene id: 879212:DESPODRAFT_RS05475
uniprot id: I5B0Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

879212:DESPODRAFT RS12965
gene id: 879212:DESPODRAFT_RS12965
uniprot id: I5B4R8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS17715
gene id: 879212:DESPODRAFT_RS17715
uniprot id: I5B7B1
names: Similarity
messages: Belongs to the UPF0045 family.

879212:DESPODRAFT RS00805
gene id: 879212:DESPODRAFT_RS00805
uniprot id: I5AY73
names: Similarity
messages: Belongs to the HupF/HypC family.

879212:DESPODRAFT RS07380
gene id: 879212:DESPODRAFT_RS07380
uniprot id: I5B1R2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

879212:DESPODRAFT RS02130
gene id: 879212:DESPODRAFT_RS02130
uniprot id: I5AYW8
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS12160
gene id: 879212:DESPODRAFT_RS12160
uniprot id: I5B4A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

879212:DESPODRAFT RS01480
gene id: 879212:DESPODRAFT_RS01480
uniprot id: I5AYJ6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

879212:DESPODRAFT RS04095
gene id: 879212:DESPODRAFT_RS04095
uniprot id: I5AZX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

879212:DESPODRAFT RS13305
gene id: 879212:DESPODRAFT_RS13305
uniprot id: I5B4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

879212:DESPODRAFT RS07750
gene id: 879212:DESPODRAFT_RS07750
uniprot id: I5B1Y0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

879212:DESPODRAFT RS09545
gene id: 879212:DESPODRAFT_RS09545
uniprot id: I5B2W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

879212:DESPODRAFT RS08635
gene id: 879212:DESPODRAFT_RS08635
uniprot id: I5B2E7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

879212:DESPODRAFT RS15340
gene id: 879212:DESPODRAFT_RS15340
uniprot id: I5B612
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

879212:DESPODRAFT RS10010
gene id: 879212:DESPODRAFT_RS10010
uniprot id: I5B356
names: Similarity
messages: Belongs to the LOG family.

879212:DESPODRAFT RS11610
gene id: 879212:DESPODRAFT_RS11610
uniprot id: I5B412
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

879212:DESPODRAFT RS11410
gene id: 879212:DESPODRAFT_RS11410
uniprot id: I5B3X0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

879212:DESPODRAFT RS06755
gene id: 879212:DESPODRAFT_RS06755
uniprot id: I5B1E6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

879212:DESPODRAFT RS13150
gene id: 879212:DESPODRAFT_RS13150
uniprot id: I5B4U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

879212:DESPODRAFT RS15200
gene id: 879212:DESPODRAFT_RS15200
uniprot id: I5B5Y5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

879212:DESPODRAFT RS13740
gene id: 879212:DESPODRAFT_RS13740
uniprot id: I5B556
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

879212:DESPODRAFT RS16960
gene id: 879212:DESPODRAFT_RS16960
uniprot id: I5B6X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

879212:DESPODRAFT RS00650
gene id: 879212:DESPODRAFT_RS00650
uniprot id: I5AY43
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

879212:DESPODRAFT RS16930
gene id: 879212:DESPODRAFT_RS16930
uniprot id: I5B6W8
names: Similarity
messages: Belongs to the DapB family.

879212:DESPODRAFT RS06830
gene id: 879212:DESPODRAFT_RS06830
uniprot id: I5B1G0
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS05225
gene id: 879212:DESPODRAFT_RS05225
uniprot id: I5B0K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

879212:DESPODRAFT RS14195
gene id: 879212:DESPODRAFT_RS14195
uniprot id: I5B5E3
names: Similarity
messages: Belongs to the UPF0102 family.

879212:DESPODRAFT RS10910
gene id: 879212:DESPODRAFT_RS10910
uniprot id: I5B3M3
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS03860
gene id: 879212:DESPODRAFT_RS03860
uniprot id: I5AZT3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

879212:DESPODRAFT RS07640
gene id: 879212:DESPODRAFT_RS07640
uniprot id: I5B1W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

879212:DESPODRAFT RS12090
gene id: 879212:DESPODRAFT_RS12090
uniprot id: I5B493
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

879212:DESPODRAFT RS14775
gene id: 879212:DESPODRAFT_RS14775
uniprot id: I5B5Q5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

879212:DESPODRAFT RS12075
gene id: 879212:DESPODRAFT_RS12075
uniprot id: I5B490
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

879212:DESPODRAFT RS00770
gene id: 879212:DESPODRAFT_RS00770
uniprot id: I5AY67
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

879212:DESPODRAFT RS10095
gene id: 879212:DESPODRAFT_RS10095
uniprot id: I5B372
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

879212:DESPODRAFT RS14510
gene id: 879212:DESPODRAFT_RS14510
uniprot id: I5B5K6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

879212:DESPODRAFT RS00270
gene id: 879212:DESPODRAFT_RS00270
uniprot id: I5AXX4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

879212:DESPODRAFT RS16040
gene id: 879212:DESPODRAFT_RS16040
uniprot id: I5B6E6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

879212:DESPODRAFT RS11740
gene id: 879212:DESPODRAFT_RS11740
uniprot id: I5B433
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

879212:DESPODRAFT RS13325
gene id: 879212:DESPODRAFT_RS13325
uniprot id: I5B4Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

879212:DESPODRAFT RS02650
gene id: 879212:DESPODRAFT_RS02650
uniprot id: I5AZ67
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

879212:DESPODRAFT RS13975
gene id: 879212:DESPODRAFT_RS13975
uniprot id: I5B5A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

879212:DESPODRAFT RS15950
gene id: 879212:DESPODRAFT_RS15950
uniprot id: I5B6C8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

879212:DESPODRAFT RS03100
gene id: 879212:DESPODRAFT_RS03100
uniprot id: I5AZF1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

879212:DESPODRAFT RS03175
gene id: 879212:DESPODRAFT_RS03175
uniprot id: I5AZG6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

879212:DESPODRAFT RS13245
gene id: 879212:DESPODRAFT_RS13245
uniprot id: I5B4W8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

879212:DESPODRAFT RS12310
gene id: 879212:DESPODRAFT_RS12310
uniprot id: I5B4D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

879212:DESPODRAFT RS00925
gene id: 879212:DESPODRAFT_RS00925
uniprot id: I5AY98
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

879212:DESPODRAFT RS02140
gene id: 879212:DESPODRAFT_RS02140
uniprot id: I5AYX0
names: Function
names: Subunit
messages: Homodimer.
messages: Represses transcription of the icaADBC operon necessary for biofilm production.

879212:DESPODRAFT RS04895
gene id: 879212:DESPODRAFT_RS04895
uniprot id: I5B0D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

879212:DESPODRAFT RS04650
gene id: 879212:DESPODRAFT_RS04650
uniprot id: I5B082
names: Similarity
messages: Belongs to the universal stress protein A family.

879212:DESPODRAFT RS02565
gene id: 879212:DESPODRAFT_RS02565
uniprot id: I5AZ50
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS13345
gene id: 879212:DESPODRAFT_RS13345
uniprot id: I5B4Y8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

879212:DESPODRAFT RS12105
gene id: 879212:DESPODRAFT_RS12105
uniprot id: I5B496
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

879212:DESPODRAFT RS16730
gene id: 879212:DESPODRAFT_RS16730
uniprot id: I5B6S9
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

879212:DESPODRAFT RS03495
gene id: 879212:DESPODRAFT_RS03495
uniprot id: I5AZM1
names: Similarity
messages: Belongs to the HsdR family.

879212:DESPODRAFT RS08620
gene id: 879212:DESPODRAFT_RS08620
uniprot id: I5B2E4
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS11145
gene id: 879212:DESPODRAFT_RS11145
uniprot id: I5B3R8
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS10100
gene id: 879212:DESPODRAFT_RS10100
uniprot id: I5B373
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

879212:DESPODRAFT RS08705
gene id: 879212:DESPODRAFT_RS08705
uniprot id: I5B2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

879212:DESPODRAFT RS16445
gene id: 879212:DESPODRAFT_RS16445
uniprot id: I5B6M3
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS12905
gene id: 879212:DESPODRAFT_RS12905
uniprot id: I5B4Q6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

879212:DESPODRAFT RS12590
gene id: 879212:DESPODRAFT_RS12590
uniprot id: I5B4J4
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

879212:DESPODRAFT RS08030
gene id: 879212:DESPODRAFT_RS08030
uniprot id: I5B234
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

879212:DESPODRAFT RS06560
gene id: 879212:DESPODRAFT_RS06560
uniprot id: I5B1B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

879212:DESPODRAFT RS08775
gene id: 879212:DESPODRAFT_RS08775
uniprot id: I5B2H3
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS07215
gene id: 879212:DESPODRAFT_RS07215
uniprot id: I5B1N3
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS11990
gene id: 879212:DESPODRAFT_RS11990
uniprot id: I5B479
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

879212:DESPODRAFT RS17235
gene id: 879212:DESPODRAFT_RS17235
uniprot id: I5B728
names: Similarity
messages: Belongs to the Gfa family.

879212:DESPODRAFT RS03865
gene id: 879212:DESPODRAFT_RS03865
uniprot id: I5AZT4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

879212:DESPODRAFT RS03870
gene id: 879212:DESPODRAFT_RS03870
uniprot id: I5AZT5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

879212:DESPODRAFT RS07620
gene id: 879212:DESPODRAFT_RS07620
uniprot id: I5B1W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

879212:DESPODRAFT RS14805
gene id: 879212:DESPODRAFT_RS14805
uniprot id: I5B5R1
names: Similarity
messages: Belongs to the YjdM family.

879212:DESPODRAFT RS04950
gene id: 879212:DESPODRAFT_RS04950
uniprot id: I5B0E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

879212:DESPODRAFT RS15570
gene id: 879212:DESPODRAFT_RS15570
uniprot id: I5B653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Belongs to the universal stress protein A family.
messages: Membrane

879212:DESPODRAFT RS12085
gene id: 879212:DESPODRAFT_RS12085
uniprot id: I5B492
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

879212:DESPODRAFT RS16050
gene id: 879212:DESPODRAFT_RS16050
uniprot id: I5B6E8
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

879212:DESPODRAFT RS03560
gene id: 879212:DESPODRAFT_RS03560
uniprot id: I5AZN1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

879212:DESPODRAFT RS03105
gene id: 879212:DESPODRAFT_RS03105
uniprot id: I5AZF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

879212:DESPODRAFT RS15915
gene id: 879212:DESPODRAFT_RS15915
uniprot id: I5B6C2
names: Similarity
messages: Belongs to the peptidase C40 family.

879212:DESPODRAFT RS12755
gene id: 879212:DESPODRAFT_RS12755
uniprot id: I5B4M7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

879212:DESPODRAFT RS06210
gene id: 879212:DESPODRAFT_RS06210
uniprot id: I5B145
names: Similarity
messages: Belongs to the UPF0047 family.

879212:DESPODRAFT RS15490
gene id: 879212:DESPODRAFT_RS15490
uniprot id: I5B639
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

879212:DESPODRAFT RS12265
gene id: 879212:DESPODRAFT_RS12265
uniprot id: I5B4D0
names: Similarity
messages: Belongs to the peptidase M20A family.

879212:DESPODRAFT RS13380
gene id: 879212:DESPODRAFT_RS13380
uniprot id: I5B4Z5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

879212:DESPODRAFT RS10185
gene id: 879212:DESPODRAFT_RS10185
uniprot id: I5B387
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

879212:DESPODRAFT RS03540
gene id: 879212:DESPODRAFT_RS03540
uniprot id: I5AZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

879212:DESPODRAFT RS14820
gene id: 879212:DESPODRAFT_RS14820
uniprot id: I5B5R4
names: Subunit
messages: Heterodimer of a large and a small subunit.

879212:DESPODRAFT RS16015
gene id: 879212:DESPODRAFT_RS16015
uniprot id: I5B6E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

879212:DESPODRAFT RS15250
gene id: 879212:DESPODRAFT_RS15250
uniprot id: I5B5Z7
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

879212:DESPODRAFT RS10510
gene id: 879212:DESPODRAFT_RS10510
uniprot id: I5B3E8
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS07595
gene id: 879212:DESPODRAFT_RS07595
uniprot id: I5B1V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

879212:DESPODRAFT RS14415
gene id: 879212:DESPODRAFT_RS14415
uniprot id: I5B5I7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

879212:DESPODRAFT RS07505
gene id: 879212:DESPODRAFT_RS07505
uniprot id: I5B1T7
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS16625
gene id: 879212:DESPODRAFT_RS16625
uniprot id: I5B6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

879212:DESPODRAFT RS07080
gene id: 879212:DESPODRAFT_RS07080
uniprot id: I5B1K8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

879212:DESPODRAFT RS02525
gene id: 879212:DESPODRAFT_RS02525
uniprot id: I5AZ43
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS10595
gene id: 879212:DESPODRAFT_RS10595
uniprot id: I5B3G2
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

879212:DESPODRAFT RS03895
gene id: 879212:DESPODRAFT_RS03895
uniprot id: I5AZT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

879212:DESPODRAFT RS15400
gene id: 879212:DESPODRAFT_RS15400
uniprot id: I5B624
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

879212:DESPODRAFT RS16100
gene id: 879212:DESPODRAFT_RS16100
uniprot id: I5B6F8
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS16005
gene id: 879212:DESPODRAFT_RS16005
uniprot id: I5B6D9
names: Similarity
messages: Belongs to the RecJ family.

879212:DESPODRAFT RS05470
gene id: 879212:DESPODRAFT_RS05470
uniprot id: I5B0Q0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

879212:DESPODRAFT RS04400
gene id: 879212:DESPODRAFT_RS04400
uniprot id: I5B036
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS17810
gene id: 879212:DESPODRAFT_RS17810
uniprot id: I5B7C8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

879212:DESPODRAFT RS01615
gene id: 879212:DESPODRAFT_RS01615
uniprot id: I5AYM1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

879212:DESPODRAFT RS03360
gene id: 879212:DESPODRAFT_RS03360
uniprot id: I5AZJ8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

879212:DESPODRAFT RS04620
gene id: 879212:DESPODRAFT_RS04620
uniprot id: I5B076
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

879212:DESPODRAFT RS06955
gene id: 879212:DESPODRAFT_RS06955
uniprot id: I5B1I5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

879212:DESPODRAFT RS00945
gene id: 879212:DESPODRAFT_RS00945
uniprot id: I5AYA2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

879212:DESPODRAFT RS05345
gene id: 879212:DESPODRAFT_RS05345
uniprot id: I5B0M5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

879212:DESPODRAFT RS07210
gene id: 879212:DESPODRAFT_RS07210
uniprot id: I5B1N2
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS12145
gene id: 879212:DESPODRAFT_RS12145
uniprot id: I5B4A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

879212:DESPODRAFT RS09135
gene id: 879212:DESPODRAFT_RS09135
uniprot id: I5B2P0
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

879212:DESPODRAFT RS01515
gene id: 879212:DESPODRAFT_RS01515
uniprot id: I5AYK2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

879212:DESPODRAFT RS17295
gene id: 879212:DESPODRAFT_RS17295
uniprot id: I5B739
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

879212:DESPODRAFT RS05150
gene id: 879212:DESPODRAFT_RS05150
uniprot id: I5B0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS04815
gene id: 879212:DESPODRAFT_RS04815
uniprot id: I5B0B5
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS04250
gene id: 879212:DESPODRAFT_RS04250
uniprot id: I5B008
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

879212:DESPODRAFT RS09880
gene id: 879212:DESPODRAFT_RS09880
uniprot id: I5B331
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879212:DESPODRAFT RS14465
gene id: 879212:DESPODRAFT_RS14465
uniprot id: I5B5J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

879212:DESPODRAFT RS08575
gene id: 879212:DESPODRAFT_RS08575
uniprot id: I5B2D6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

879212:DESPODRAFT RS05105
gene id: 879212:DESPODRAFT_RS05105
uniprot id: I5B0H5
names: Subcellular Location Annotation
messages: Cytoplasm

879212:DESPODRAFT RS17345
gene id: 879212:DESPODRAFT_RS17345
uniprot id: I5B748
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

879212:DESPODRAFT RS07675
gene id: 879212:DESPODRAFT_RS07675
uniprot id: I5B1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS14795
gene id: 879212:DESPODRAFT_RS14795
uniprot id: I5B5Q9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

879212:DESPODRAFT RS10955
gene id: 879212:DESPODRAFT_RS10955
uniprot id: I5B3N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

879212:DESPODRAFT RS03790
gene id: 879212:DESPODRAFT_RS03790
uniprot id: I5AZS0
names: Similarity
messages: Belongs to the HdrA family.

879212:DESPODRAFT RS02895
gene id: 879212:DESPODRAFT_RS02895
uniprot id: I5AZB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

879212:DESPODRAFT RS18150
gene id: 879212:DESPODRAFT_RS18150
uniprot id: I5B7J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

879212:DESPODRAFT RS02455
gene id: 879212:DESPODRAFT_RS02455
uniprot id: I5AZ31
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS17075
gene id: 879212:DESPODRAFT_RS17075
uniprot id: I5B6Z6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS08700
gene id: 879212:DESPODRAFT_RS08700
uniprot id: I5B2F9
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS14875
gene id: 879212:DESPODRAFT_RS14875
uniprot id: I5B5S4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879212:DESPODRAFT RS08710
gene id: 879212:DESPODRAFT_RS08710
uniprot id: I5B2G1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

879212:DESPODRAFT RS05220
gene id: 879212:DESPODRAFT_RS05220
uniprot id: I5B0K0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

879212:DESPODRAFT RS02400
gene id: 879212:DESPODRAFT_RS02400
uniprot id: I5AZ19
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS03590
gene id: 879212:DESPODRAFT_RS03590
uniprot id: I5AZN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

879212:DESPODRAFT RS17585
gene id: 879212:DESPODRAFT_RS17585
uniprot id: I5B793
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS17290
gene id: 879212:DESPODRAFT_RS17290
uniprot id: I5B738
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

879212:DESPODRAFT RS16370
gene id: 879212:DESPODRAFT_RS16370
uniprot id: I5B6L2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

879212:DESPODRAFT RS02295
gene id: 879212:DESPODRAFT_RS02295
uniprot id: I5AYZ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane

879212:DESPODRAFT RS10075
gene id: 879212:DESPODRAFT_RS10075
uniprot id: I5B368
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

879212:DESPODRAFT RS18230
gene id: 879212:DESPODRAFT_RS18230
uniprot id: I5B7K7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

879212:DESPODRAFT RS10025
gene id: 879212:DESPODRAFT_RS10025
uniprot id: I5B359
names: Similarity
messages: Belongs to the peptidase M24B family.

879212:DESPODRAFT RS05230
gene id: 879212:DESPODRAFT_RS05230
uniprot id: I5B0K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

879212:DESPODRAFT RS00950
gene id: 879212:DESPODRAFT_RS00950
uniprot id: I5AYA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS02740
gene id: 879212:DESPODRAFT_RS02740
uniprot id: I5AZ84
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

879212:DESPODRAFT RS10775
gene id: 879212:DESPODRAFT_RS10775
uniprot id: I5B3J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS00285
gene id: 879212:DESPODRAFT_RS00285
uniprot id: I5AXX7
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

879212:DESPODRAFT RS05180
gene id: 879212:DESPODRAFT_RS05180
uniprot id: I5B0J2
names: Similarity
messages: Belongs to the TrpR family.

879212:DESPODRAFT RS04225
gene id: 879212:DESPODRAFT_RS04225
uniprot id: I5B003
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS00780
gene id: 879212:DESPODRAFT_RS00780
uniprot id: I5AY69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

879212:DESPODRAFT RS00820
gene id: 879212:DESPODRAFT_RS00820
uniprot id: I5AY76
names: Similarity
messages: Belongs to the HypE family.

879212:DESPODRAFT RS01745
gene id: 879212:DESPODRAFT_RS01745
uniprot id: I5AYP8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

879212:DESPODRAFT RS04180
gene id: 879212:DESPODRAFT_RS04180
uniprot id: I5AZZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

879212:DESPODRAFT RS00885
gene id: 879212:DESPODRAFT_RS00885
uniprot id: I5AY90
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

879212:DESPODRAFT RS00955
gene id: 879212:DESPODRAFT_RS00955
uniprot id: I5AYA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

879212:DESPODRAFT RS17170
gene id: 879212:DESPODRAFT_RS17170
uniprot id: I5B715
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

879212:DESPODRAFT RS17970
gene id: 879212:DESPODRAFT_RS17970
uniprot id: I5B7F8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

879212:DESPODRAFT RS16110
gene id: 879212:DESPODRAFT_RS16110
uniprot id: I5B6G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

879212:DESPODRAFT RS01955
gene id: 879212:DESPODRAFT_RS01955
uniprot id: I5AYT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

879212:DESPODRAFT RS01485
gene id: 879212:DESPODRAFT_RS01485
uniprot id: I5AYJ7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS04025
gene id: 879212:DESPODRAFT_RS04025
uniprot id: I5AZW3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

879212:DESPODRAFT RS08955
gene id: 879212:DESPODRAFT_RS08955
uniprot id: I5B2K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

879212:DESPODRAFT RS18925
gene id: 879212:DESPODRAFT_RS18925
uniprot id: I5B7I6
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

879212:DESPODRAFT RS13295
gene id: 879212:DESPODRAFT_RS13295
uniprot id: I5B4X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

879212:DESPODRAFT RS04860
gene id: 879212:DESPODRAFT_RS04860
uniprot id: I5B0C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

879212:DESPODRAFT RS02465
gene id: 879212:DESPODRAFT_RS02465
uniprot id: I5AZ33
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

879212:DESPODRAFT RS00690
gene id: 879212:DESPODRAFT_RS00690
uniprot id: I5AY51
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS01370
gene id: 879212:DESPODRAFT_RS01370
uniprot id: I5AYI1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

879212:DESPODRAFT RS15580
gene id: 879212:DESPODRAFT_RS15580
uniprot id: I5B655
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

879212:DESPODRAFT RS03050
gene id: 879212:DESPODRAFT_RS03050
uniprot id: I5AZE3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

879212:DESPODRAFT RS08720
gene id: 879212:DESPODRAFT_RS08720
uniprot id: I5B2G3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

879212:DESPODRAFT RS13820
gene id: 879212:DESPODRAFT_RS13820
uniprot id: I5B571
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

879212:DESPODRAFT RS00795
gene id: 879212:DESPODRAFT_RS00795
uniprot id: I5AY71
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

879212:DESPODRAFT RS16235
gene id: 879212:DESPODRAFT_RS16235
uniprot id: I5B6I4
names: Similarity
messages: Belongs to the HepT RNase toxin family.

879212:DESPODRAFT RS02055
gene id: 879212:DESPODRAFT_RS02055
uniprot id: I5AYV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

879212:DESPODRAFT RS17965
gene id: 879212:DESPODRAFT_RS17965
uniprot id: I5B7F7
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

879212:DESPODRAFT RS15625
gene id: 879212:DESPODRAFT_RS15625
uniprot id: I5B664
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

879212:DESPODRAFT RS15210
gene id: 879212:DESPODRAFT_RS15210
uniprot id: I5B5Y7
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

879212:DESPODRAFT RS10360
gene id: 879212:DESPODRAFT_RS10360
uniprot id: I5B3B8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

879212:DESPODRAFT RS01795
gene id: 879212:DESPODRAFT_RS01795
uniprot id: I5AYQ8
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS12765
gene id: 879212:DESPODRAFT_RS12765
uniprot id: I5B4M9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

879212:DESPODRAFT RS08465
gene id: 879212:DESPODRAFT_RS08465
uniprot id: I5B2B3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

879212:DESPODRAFT RS05375
gene id: 879212:DESPODRAFT_RS05375
uniprot id: I5B0N1
names: Subcellular Location Annotation
messages: Cytoplasm

879212:DESPODRAFT RS15330
gene id: 879212:DESPODRAFT_RS15330
uniprot id: I5B610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

879212:DESPODRAFT RS10580
gene id: 879212:DESPODRAFT_RS10580
uniprot id: I5B3G0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS01265
gene id: 879212:DESPODRAFT_RS01265
uniprot id: I5AYF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS17550
gene id: 879212:DESPODRAFT_RS17550
uniprot id: I5B786
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

879212:DESPODRAFT RS01925
gene id: 879212:DESPODRAFT_RS01925
uniprot id: I5AYT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

879212:DESPODRAFT RS18540
gene id: 879212:DESPODRAFT_RS18540
uniprot id: I5B049
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

879212:DESPODRAFT RS06100
gene id: 879212:DESPODRAFT_RS06100
uniprot id: I5B123
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

879212:DESPODRAFT RS04845
gene id: 879212:DESPODRAFT_RS04845
uniprot id: I5B0C2
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

879212:DESPODRAFT RS01700
gene id: 879212:DESPODRAFT_RS01700
uniprot id: I5AYN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS11195
gene id: 879212:DESPODRAFT_RS11195
uniprot id: I5B3S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

879212:DESPODRAFT RS02790
gene id: 879212:DESPODRAFT_RS02790
uniprot id: I5AZ94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

879212:DESPODRAFT RS05155
gene id: 879212:DESPODRAFT_RS05155
uniprot id: I5B0I7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

879212:DESPODRAFT RS08480
gene id: 879212:DESPODRAFT_RS08480
uniprot id: I5B2B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

879212:DESPODRAFT RS11470
gene id: 879212:DESPODRAFT_RS11470
uniprot id: I5B3Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

879212:DESPODRAFT RS08660
gene id: 879212:DESPODRAFT_RS08660
uniprot id: I5B2F2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

879212:DESPODRAFT RS06790
gene id: 879212:DESPODRAFT_RS06790
uniprot id: I5B1F3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

879212:DESPODRAFT RS03260
gene id: 879212:DESPODRAFT_RS03260
uniprot id: I5AZH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

879212:DESPODRAFT RS13365
gene id: 879212:DESPODRAFT_RS13365
uniprot id: I5B4Z2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

879212:DESPODRAFT RS07150
gene id: 879212:DESPODRAFT_RS07150
uniprot id: I5B1M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

879212:DESPODRAFT RS06485
gene id: 879212:DESPODRAFT_RS06485
uniprot id: I5B197
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

879212:DESPODRAFT RS00935
gene id: 879212:DESPODRAFT_RS00935
uniprot id: I5AYA0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

879212:DESPODRAFT RS14535
gene id: 879212:DESPODRAFT_RS14535
uniprot id: I5B5L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

879212:DESPODRAFT RS05545
gene id: 879212:DESPODRAFT_RS05545
uniprot id: I5B0R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

879212:DESPODRAFT RS09270
gene id: 879212:DESPODRAFT_RS09270
uniprot id: I5B2R7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

879212:DESPODRAFT RS14285
gene id: 879212:DESPODRAFT_RS14285
uniprot id: I5B5G1
names: Similarity
messages: Belongs to the leucine-binding protein family.

879212:DESPODRAFT RS05745
gene id: 879212:DESPODRAFT_RS05745
uniprot id: I5B0V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

879212:DESPODRAFT RS14835
gene id: 879212:DESPODRAFT_RS14835
uniprot id: I5B5R7
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS09535
gene id: 879212:DESPODRAFT_RS09535
uniprot id: I5B2W6
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS00875
gene id: 879212:DESPODRAFT_RS00875
uniprot id: I5AY88
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS11960
gene id: 879212:DESPODRAFT_RS11960
uniprot id: I5B473
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879212:DESPODRAFT RS06125
gene id: 879212:DESPODRAFT_RS06125
uniprot id: I5B128
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

879212:DESPODRAFT RS11435
gene id: 879212:DESPODRAFT_RS11435
uniprot id: I5B3X5
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS06480
gene id: 879212:DESPODRAFT_RS06480
uniprot id: I5B196
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

879212:DESPODRAFT RS14585
gene id: 879212:DESPODRAFT_RS14585
uniprot id: I5B5M0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS06295
gene id: 879212:DESPODRAFT_RS06295
uniprot id: I5B159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS06765
gene id: 879212:DESPODRAFT_RS06765
uniprot id: I5B1E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

879212:DESPODRAFT RS06985
gene id: 879212:DESPODRAFT_RS06985
uniprot id: I5B1J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS09990
gene id: 879212:DESPODRAFT_RS09990
uniprot id: I5B352
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879212:DESPODRAFT RS17915
gene id: 879212:DESPODRAFT_RS17915
uniprot id: I5B7E7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

879212:DESPODRAFT RS12415
gene id: 879212:DESPODRAFT_RS12415
uniprot id: I5B4F9
names: Similarity
messages: Belongs to the HepT RNase toxin family.

879212:DESPODRAFT RS04305
gene id: 879212:DESPODRAFT_RS04305
uniprot id: I5B017
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS06085
gene id: 879212:DESPODRAFT_RS06085
uniprot id: I5B120
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS05045
gene id: 879212:DESPODRAFT_RS05045
uniprot id: I5B0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

879212:DESPODRAFT RS04120
gene id: 879212:DESPODRAFT_RS04120
uniprot id: I5AZY2
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS13575
gene id: 879212:DESPODRAFT_RS13575
uniprot id: I5B525
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS02930
gene id: 879212:DESPODRAFT_RS02930
uniprot id: I5AZC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

879212:DESPODRAFT RS12110
gene id: 879212:DESPODRAFT_RS12110
uniprot id: I5B497
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

879212:DESPODRAFT RS03825
gene id: 879212:DESPODRAFT_RS03825
uniprot id: I5AZS6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

879212:DESPODRAFT RS14600
gene id: 879212:DESPODRAFT_RS14600
uniprot id: I5B5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

879212:DESPODRAFT RS16030
gene id: 879212:DESPODRAFT_RS16030
uniprot id: I5B6E4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

879212:DESPODRAFT RS10680
gene id: 879212:DESPODRAFT_RS10680
uniprot id: I5B3H7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

879212:DESPODRAFT RS04455
gene id: 879212:DESPODRAFT_RS04455
uniprot id: I5B046
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS03715
gene id: 879212:DESPODRAFT_RS03715
uniprot id: I5AZQ6
names: Similarity
messages: Belongs to the peptidase S24 family.

879212:DESPODRAFT RS01100
gene id: 879212:DESPODRAFT_RS01100
uniprot id: I5AYC8
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

879212:DESPODRAFT RS10550
gene id: 879212:DESPODRAFT_RS10550
uniprot id: I5B3F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS14580
gene id: 879212:DESPODRAFT_RS14580
uniprot id: I5B5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS11685
gene id: 879212:DESPODRAFT_RS11685
uniprot id: I5B422
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

879212:DESPODRAFT RS15335
gene id: 879212:DESPODRAFT_RS15335
uniprot id: I5B611
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

879212:DESPODRAFT RS10755
gene id: 879212:DESPODRAFT_RS10755
uniprot id: I5B3J2
names: Similarity
messages: Belongs to the universal stress protein A family.

879212:DESPODRAFT RS01025
gene id: 879212:DESPODRAFT_RS01025
uniprot id: I5AYB8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

879212:DESPODRAFT RS01640
gene id: 879212:DESPODRAFT_RS01640
uniprot id: I5AYM7
names: Subcellular Location Annotation
messages: Cytoplasm

879212:DESPODRAFT RS03855
gene id: 879212:DESPODRAFT_RS03855
uniprot id: I5AZT2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

879212:DESPODRAFT RS00845
gene id: 879212:DESPODRAFT_RS00845
uniprot id: I5B212
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

879212:DESPODRAFT RS11765
gene id: 879212:DESPODRAFT_RS11765
uniprot id: I5B437
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

879212:DESPODRAFT RS11945
gene id: 879212:DESPODRAFT_RS11945
uniprot id: I5B470
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

879212:DESPODRAFT RS14095
gene id: 879212:DESPODRAFT_RS14095
uniprot id: I5B5C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

879212:DESPODRAFT RS10965
gene id: 879212:DESPODRAFT_RS10965
uniprot id: I5B3N4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

879212:DESPODRAFT RS10005
gene id: 879212:DESPODRAFT_RS10005
uniprot id: I5B355
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879212:DESPODRAFT RS12155
gene id: 879212:DESPODRAFT_RS12155
uniprot id: I5B4A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

879212:DESPODRAFT RS11165
gene id: 879212:DESPODRAFT_RS11165
uniprot id: I5B3S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

879212:DESPODRAFT RS03460
gene id: 879212:DESPODRAFT_RS03460
uniprot id: I5AZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

879212:DESPODRAFT RS15860
gene id: 879212:DESPODRAFT_RS15860
uniprot id: I5B6B1
names: Similarity
messages: Belongs to the HdrA family.

879212:DESPODRAFT RS15385
gene id: 879212:DESPODRAFT_RS15385
uniprot id: I5B621
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

879212:DESPODRAFT RS13630
gene id: 879212:DESPODRAFT_RS13630
uniprot id: I5B536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

879212:DESPODRAFT RS14590
gene id: 879212:DESPODRAFT_RS14590
uniprot id: I5B5M1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

879212:DESPODRAFT RS16790
gene id: 879212:DESPODRAFT_RS16790
uniprot id: I5B6U1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

879212:DESPODRAFT RS16020
gene id: 879212:DESPODRAFT_RS16020
uniprot id: I5B6E2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

879212:DESPODRAFT RS02770
gene id: 879212:DESPODRAFT_RS02770
uniprot id: I5AZ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

879212:DESPODRAFT RS00895
gene id: 879212:DESPODRAFT_RS00895
uniprot id: I5AY92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

879212:DESPODRAFT RS17450
gene id: 879212:DESPODRAFT_RS17450
uniprot id: I5B769
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

879212:DESPODRAFT RS01200
gene id: 879212:DESPODRAFT_RS01200
uniprot id: I5AYE8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

879212:DESPODRAFT RS13390
gene id: 879212:DESPODRAFT_RS13390
uniprot id: I5B4Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

879212:DESPODRAFT RS07960
gene id: 879212:DESPODRAFT_RS07960
uniprot id: I5B220
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

879212:DESPODRAFT RS12065
gene id: 879212:DESPODRAFT_RS12065
uniprot id: I5B488
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

879212:DESPODRAFT RS02040
gene id: 879212:DESPODRAFT_RS02040
uniprot id: I5AYV1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

879212:DESPODRAFT RS04975
gene id: 879212:DESPODRAFT_RS04975
uniprot id: I5B0E9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

879212:DESPODRAFT RS13675
gene id: 879212:DESPODRAFT_RS13675
uniprot id: I5B545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

879212:DESPODRAFT RS11395
gene id: 879212:DESPODRAFT_RS11395
uniprot id: I5B3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

879212:DESPODRAFT RS12225
gene id: 879212:DESPODRAFT_RS12225
uniprot id: I5B4C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

879212:DESPODRAFT RS05530
gene id: 879212:DESPODRAFT_RS05530
uniprot id: I5B0R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

879212:DESPODRAFT RS17620
gene id: 879212:DESPODRAFT_RS17620
uniprot id: I5B7A0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

879212:DESPODRAFT RS09885
gene id: 879212:DESPODRAFT_RS09885
uniprot id: I5B332
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879212:DESPODRAFT RS16635
gene id: 879212:DESPODRAFT_RS16635
uniprot id: I5B6R2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

879212:DESPODRAFT RS01195
gene id: 879212:DESPODRAFT_RS01195
uniprot id: I5AYE7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

879212:DESPODRAFT RS03885
gene id: 879212:DESPODRAFT_RS03885
uniprot id: I5AZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

879212:DESPODRAFT RS02170
gene id: 879212:DESPODRAFT_RS02170
uniprot id: I5AYX6
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS04865
gene id: 879212:DESPODRAFT_RS04865
uniprot id: I5B0C6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

879212:DESPODRAFT RS06670
gene id: 879212:DESPODRAFT_RS06670
uniprot id: I5B1D1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

879212:DESPODRAFT RS02860
gene id: 879212:DESPODRAFT_RS02860
uniprot id: I5AZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

879212:DESPODRAFT RS00920
gene id: 879212:DESPODRAFT_RS00920
uniprot id: I5AY97
names: Similarity
messages: Belongs to the thioredoxin family.

879212:DESPODRAFT RS03675
gene id: 879212:DESPODRAFT_RS03675
uniprot id: I5AZQ3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

879212:DESPODRAFT RS09920
gene id: 879212:DESPODRAFT_RS09920
uniprot id: I5B338
names: Similarity
messages: Belongs to the UPF0751 family.

879212:DESPODRAFT RS13580
gene id: 879212:DESPODRAFT_RS13580
uniprot id: I5B526
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

879212:DESPODRAFT RS07515
gene id: 879212:DESPODRAFT_RS07515
uniprot id: I5B1T9
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS12345
gene id: 879212:DESPODRAFT_RS12345
uniprot id: I5B4E6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

879212:DESPODRAFT RS02945
gene id: 879212:DESPODRAFT_RS02945
uniprot id: I5AZC4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

879212:DESPODRAFT RS00610
gene id: 879212:DESPODRAFT_RS00610
uniprot id: I5AY35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS11870
gene id: 879212:DESPODRAFT_RS11870
uniprot id: I5B458
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS07825
gene id: 879212:DESPODRAFT_RS07825
uniprot id: I5B1Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

879212:DESPODRAFT RS09565
gene id: 879212:DESPODRAFT_RS09565
uniprot id: I5B2X2
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS14780
gene id: 879212:DESPODRAFT_RS14780
uniprot id: I5B5Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

879212:DESPODRAFT RS06460
gene id: 879212:DESPODRAFT_RS06460
uniprot id: I5B192
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS02435
gene id: 879212:DESPODRAFT_RS02435
uniprot id: I5AZ26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

879212:DESPODRAFT RS12570
gene id: 879212:DESPODRAFT_RS12570
uniprot id: I5B4J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

879212:DESPODRAFT RS17685
gene id: 879212:DESPODRAFT_RS17685
uniprot id: I5B7A9
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

879212:DESPODRAFT RS02890
gene id: 879212:DESPODRAFT_RS02890
uniprot id: I5AZB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

879212:DESPODRAFT RS00430
gene id: 879212:DESPODRAFT_RS00430
uniprot id: I5AY01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

879212:DESPODRAFT RS08870
gene id: 879212:DESPODRAFT_RS08870
uniprot id: I5B2J1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

879212:DESPODRAFT RS01975
gene id: 879212:DESPODRAFT_RS01975
uniprot id: I5AYT9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

879212:DESPODRAFT RS14275
gene id: 879212:DESPODRAFT_RS14275
uniprot id: I5B5F9
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS00450
gene id: 879212:DESPODRAFT_RS00450
uniprot id: I5AY06
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS01335
gene id: 879212:DESPODRAFT_RS01335
uniprot id: I5AYH3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

879212:DESPODRAFT RS04375
gene id: 879212:DESPODRAFT_RS04375
uniprot id: I5B031
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

879212:DESPODRAFT RS17545
gene id: 879212:DESPODRAFT_RS17545
uniprot id: I5B785
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

879212:DESPODRAFT RS09540
gene id: 879212:DESPODRAFT_RS09540
uniprot id: I5B2W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

879212:DESPODRAFT RS13720
gene id: 879212:DESPODRAFT_RS13720
uniprot id: I5B552
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

879212:DESPODRAFT RS10265
gene id: 879212:DESPODRAFT_RS10265
uniprot id: I5B3A1
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS07585
gene id: 879212:DESPODRAFT_RS07585
uniprot id: I5B1V3
names: Similarity
messages: Belongs to the peptidase S66 family.

879212:DESPODRAFT RS06975
gene id: 879212:DESPODRAFT_RS06975
uniprot id: I5B1I9
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS03795
gene id: 879212:DESPODRAFT_RS03795
uniprot id: I5AZS1
names: Similarity
messages: Belongs to the HdrA family.

879212:DESPODRAFT RS17855
gene id: 879212:DESPODRAFT_RS17855
uniprot id: I5B7D7
names: Similarity
messages: Belongs to the Lgt family.

879212:DESPODRAFT RS07645
gene id: 879212:DESPODRAFT_RS07645
uniprot id: I5B1W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

879212:DESPODRAFT RS01870
gene id: 879212:DESPODRAFT_RS01870
uniprot id: I5AYS1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

879212:DESPODRAFT RS10085
gene id: 879212:DESPODRAFT_RS10085
uniprot id: I5B370
names: Similarity
messages: Belongs to the universal stress protein A family.

879212:DESPODRAFT RS11100
gene id: 879212:DESPODRAFT_RS11100
uniprot id: I5B3Q9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

879212:DESPODRAFT RS07160
gene id: 879212:DESPODRAFT_RS07160
uniprot id: I5B1M2
names: Similarity
messages: Belongs to the peptidase S41A family.

879212:DESPODRAFT RS06545
gene id: 879212:DESPODRAFT_RS06545
uniprot id: I5B1A9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879212:DESPODRAFT RS08690
gene id: 879212:DESPODRAFT_RS08690
uniprot id: I5B2F8
names: Function
names: Subunit
messages: Homodimer.
messages: Represses transcription of the icaADBC operon necessary for biofilm production.

879212:DESPODRAFT RS05085
gene id: 879212:DESPODRAFT_RS05085
uniprot id: I5B0H1
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

879212:DESPODRAFT RS10725
gene id: 879212:DESPODRAFT_RS10725
uniprot id: I5B3I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS15710
gene id: 879212:DESPODRAFT_RS15710
uniprot id: I5B681
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

879212:DESPODRAFT RS07835
gene id: 879212:DESPODRAFT_RS07835
uniprot id: I5B1Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

879212:DESPODRAFT RS07005
gene id: 879212:DESPODRAFT_RS07005
uniprot id: I5B1J5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

879212:DESPODRAFT RS01395
gene id: 879212:DESPODRAFT_RS01395
uniprot id: I5AYI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

879212:DESPODRAFT RS18415
gene id: 879212:DESPODRAFT_RS18415
uniprot id: I5B7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

879212:DESPODRAFT RS13340
gene id: 879212:DESPODRAFT_RS13340
uniprot id: I5B4Y7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

879212:DESPODRAFT RS04585
gene id: 879212:DESPODRAFT_RS04585
uniprot id: I5B068
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

879212:DESPODRAFT RS11930
gene id: 879212:DESPODRAFT_RS11930
uniprot id: I5B466
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

879212:DESPODRAFT RS17175
gene id: 879212:DESPODRAFT_RS17175
uniprot id: I5B716
names: Similarity
messages: Belongs to the SAICAR synthetase family.

879212:DESPODRAFT RS01250
gene id: 879212:DESPODRAFT_RS01250
uniprot id: I5AYF6
names: Similarity
messages: Belongs to the methyltransferase superfamily. PrmA family.

879212:DESPODRAFT RS14080
gene id: 879212:DESPODRAFT_RS14080
uniprot id: I5B5C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

879212:DESPODRAFT RS02865
gene id: 879212:DESPODRAFT_RS02865
uniprot id: I5AZA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

879212:DESPODRAFT RS11345
gene id: 879212:DESPODRAFT_RS11345
uniprot id: I5B3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

879212:DESPODRAFT RS13300
gene id: 879212:DESPODRAFT_RS13300
uniprot id: I5B4X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

879212:DESPODRAFT RS01365
gene id: 879212:DESPODRAFT_RS01365
uniprot id: I5AYI0
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

879212:DESPODRAFT RS02620
gene id: 879212:DESPODRAFT_RS02620
uniprot id: I5AZ61
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

879212:DESPODRAFT RS09120
gene id: 879212:DESPODRAFT_RS09120
uniprot id: I5B2N9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

879212:DESPODRAFT RS04780
gene id: 879212:DESPODRAFT_RS04780
uniprot id: I5B0A7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

879212:DESPODRAFT RS15475
gene id: 879212:DESPODRAFT_RS15475
uniprot id: I5B636
names: Similarity
messages: Belongs to the LarC family.

879212:DESPODRAFT RS10805
gene id: 879212:DESPODRAFT_RS10805
uniprot id: I5B3K3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

879212:DESPODRAFT RS02605
gene id: 879212:DESPODRAFT_RS02605
uniprot id: I5AZ58
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

879212:DESPODRAFT RS07760
gene id: 879212:DESPODRAFT_RS07760
uniprot id: I5B1Y2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

879212:DESPODRAFT RS12100
gene id: 879212:DESPODRAFT_RS12100
uniprot id: I5B495
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

879212:DESPODRAFT RS11400
gene id: 879212:DESPODRAFT_RS11400
uniprot id: I5B3W8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

879212:DESPODRAFT RS03355
gene id: 879212:DESPODRAFT_RS03355
uniprot id: I5AZJ7
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS17935
gene id: 879212:DESPODRAFT_RS17935
uniprot id: I5B7F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

879212:DESPODRAFT RS13800
gene id: 879212:DESPODRAFT_RS13800
uniprot id: I5B567
names: Similarity
messages: Belongs to the hemerythrin family.

879212:DESPODRAFT RS18300
gene id: 879212:DESPODRAFT_RS18300
uniprot id: I5B7M2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

879212:DESPODRAFT RS01065
gene id: 879212:DESPODRAFT_RS01065
uniprot id: I5AYC2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

879212:DESPODRAFT RS11935
gene id: 879212:DESPODRAFT_RS11935
uniprot id: I5B467
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

879212:DESPODRAFT RS12205
gene id: 879212:DESPODRAFT_RS12205
uniprot id: I5B4B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

879212:DESPODRAFT RS13415
gene id: 879212:DESPODRAFT_RS13415
uniprot id: I5B502
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

879212:DESPODRAFT RS12300
gene id: 879212:DESPODRAFT_RS12300
uniprot id: I5B4D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

879212:DESPODRAFT RS18865
gene id: 879212:DESPODRAFT_RS18865
uniprot id: I5B6P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

879212:DESPODRAFT RS05160
gene id: 879212:DESPODRAFT_RS05160
uniprot id: I5B0I8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

879212:DESPODRAFT RS14045
gene id: 879212:DESPODRAFT_RS14045
uniprot id: I5B5B4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS00470
gene id: 879212:DESPODRAFT_RS00470
uniprot id: I5AY10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

879212:DESPODRAFT RS16440
gene id: 879212:DESPODRAFT_RS16440
uniprot id: I5B6M2
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS17285
gene id: 879212:DESPODRAFT_RS17285
uniprot id: I5B737
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

879212:DESPODRAFT RS12850
gene id: 879212:DESPODRAFT_RS12850
uniprot id: I5B4P5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS06915
gene id: 879212:DESPODRAFT_RS06915
uniprot id: I5B1H7
names: Similarity
messages: Belongs to the archease family.

879212:DESPODRAFT RS03725
gene id: 879212:DESPODRAFT_RS03725
uniprot id: I5AZQ8
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

879212:DESPODRAFT RS00420
gene id: 879212:DESPODRAFT_RS00420
uniprot id: I5AXZ9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

879212:DESPODRAFT RS07175
gene id: 879212:DESPODRAFT_RS07175
uniprot id: I5B1M5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

879212:DESPODRAFT RS05130
gene id: 879212:DESPODRAFT_RS05130
uniprot id: I5B0I2
names: Subunit
messages: Heterodimer of a large and a small subunit.

879212:DESPODRAFT RS12900
gene id: 879212:DESPODRAFT_RS12900
uniprot id: I5B4Q5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

879212:DESPODRAFT RS05170
gene id: 879212:DESPODRAFT_RS05170
uniprot id: I5B0J0
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

879212:DESPODRAFT RS06285
gene id: 879212:DESPODRAFT_RS06285
uniprot id: I5B157
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS04005
gene id: 879212:DESPODRAFT_RS04005
uniprot id: I5AZW0
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

879212:DESPODRAFT RS01670
gene id: 879212:DESPODRAFT_RS01670
uniprot id: I5AYN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

879212:DESPODRAFT RS17015
gene id: 879212:DESPODRAFT_RS17015
uniprot id: I5B6Y5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

879212:DESPODRAFT RS08965
gene id: 879212:DESPODRAFT_RS08965
uniprot id: I5B2K6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

879212:DESPODRAFT RS12340
gene id: 879212:DESPODRAFT_RS12340
uniprot id: I5B4E5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS14885
gene id: 879212:DESPODRAFT_RS14885
uniprot id: I5B5S6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

879212:DESPODRAFT RS04565
gene id: 879212:DESPODRAFT_RS04565
uniprot id: I5B064
names: Similarity
messages: Belongs to the CobH/CbiC family.

879212:DESPODRAFT RS05875
gene id: 879212:DESPODRAFT_RS05875
uniprot id: I5B0X8
names: Similarity
messages: Belongs to the GSP E family.

879212:DESPODRAFT RS16555
gene id: 879212:DESPODRAFT_RS16555
uniprot id: I5B6P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS16025
gene id: 879212:DESPODRAFT_RS16025
uniprot id: I5B6E3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

879212:DESPODRAFT RS10825
gene id: 879212:DESPODRAFT_RS10825
uniprot id: I5B3K7
names: Similarity
messages: Belongs to the pyruvate kinase family.

879212:DESPODRAFT RS13610
gene id: 879212:DESPODRAFT_RS13610
uniprot id: I5B532
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

879212:DESPODRAFT RS17720
gene id: 879212:DESPODRAFT_RS17720
uniprot id: I5B7B2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

879212:DESPODRAFT RS11700
gene id: 879212:DESPODRAFT_RS11700
uniprot id: I5B425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP I family.
messages: Membrane

879212:DESPODRAFT RS08115
gene id: 879212:DESPODRAFT_RS08115
uniprot id: I5B246
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

879212:DESPODRAFT RS14575
gene id: 879212:DESPODRAFT_RS14575
uniprot id: I5B5L8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

879212:DESPODRAFT RS05480
gene id: 879212:DESPODRAFT_RS05480
uniprot id: I5B0Q2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

879212:DESPODRAFT RS02960
gene id: 879212:DESPODRAFT_RS02960
uniprot id: I5AZC7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

879212:DESPODRAFT RS00605
gene id: 879212:DESPODRAFT_RS00605
uniprot id: I5AY34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

879212:DESPODRAFT RS03745
gene id: 879212:DESPODRAFT_RS03745
uniprot id: I5AZR2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

879212:DESPODRAFT RS04285
gene id: 879212:DESPODRAFT_RS04285
uniprot id: I5B013
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

879212:DESPODRAFT RS01710
gene id: 879212:DESPODRAFT_RS01710
uniprot id: I5AYP1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS14640
gene id: 879212:DESPODRAFT_RS14640
uniprot id: I5B5N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

879212:DESPODRAFT RS18635
gene id: 879212:DESPODRAFT_RS18635
uniprot id: I5B2E8
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

879212:DESPODRAFT RS09580
gene id: 879212:DESPODRAFT_RS09580
uniprot id: I5B2X5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

879212:DESPODRAFT RS02795
gene id: 879212:DESPODRAFT_RS02795
uniprot id: I5AZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

879212:DESPODRAFT RS14800
gene id: 879212:DESPODRAFT_RS14800
uniprot id: I5B5R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

879212:DESPODRAFT RS14125
gene id: 879212:DESPODRAFT_RS14125
uniprot id: I5B5D1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

879212:DESPODRAFT RS15380
gene id: 879212:DESPODRAFT_RS15380
uniprot id: I5B620
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS03245
gene id: 879212:DESPODRAFT_RS03245
uniprot id: I5AZH5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

879212:DESPODRAFT RS14055
gene id: 879212:DESPODRAFT_RS14055
uniprot id: I5B5B6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

879212:DESPODRAFT RS01520
gene id: 879212:DESPODRAFT_RS01520
uniprot id: I5AYK3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

879212:DESPODRAFT RS03110
gene id: 879212:DESPODRAFT_RS03110
uniprot id: I5AZF3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

879212:DESPODRAFT RS17430
gene id: 879212:DESPODRAFT_RS17430
uniprot id: I5B765
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS13780
gene id: 879212:DESPODRAFT_RS13780
uniprot id: I5B563
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

879212:DESPODRAFT RS17460
gene id: 879212:DESPODRAFT_RS17460
uniprot id: I5B771
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

879212:DESPODRAFT RS05705
gene id: 879212:DESPODRAFT_RS05705
uniprot id: I5B0U5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

879212:DESPODRAFT RS03735
gene id: 879212:DESPODRAFT_RS03735
uniprot id: I5AZR0
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

879212:DESPODRAFT RS16760
gene id: 879212:DESPODRAFT_RS16760
uniprot id: I5B6T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

879212:DESPODRAFT RS05260
gene id: 879212:DESPODRAFT_RS05260
uniprot id: I5B0K8
names: Similarity
messages: Belongs to the universal stress protein A family.

879212:DESPODRAFT RS12130
gene id: 879212:DESPODRAFT_RS12130
uniprot id: I5B4A1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

879212:DESPODRAFT RS04700
gene id: 879212:DESPODRAFT_RS04700
uniprot id: I5B091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS16580
gene id: 879212:DESPODRAFT_RS16580
uniprot id: I5B6Q1
names: Function
names: Similarity
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.

879212:DESPODRAFT RS12635
gene id: 879212:DESPODRAFT_RS12635
uniprot id: I5B4K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

879212:DESPODRAFT RS11485
gene id: 879212:DESPODRAFT_RS11485
uniprot id: I5B3Y5
names: Similarity
messages: Belongs to the YicC/YloC family.

879212:DESPODRAFT RS18825
gene id: 879212:DESPODRAFT_RS18825
uniprot id: I5B673
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

879212:DESPODRAFT RS17315
gene id: 879212:DESPODRAFT_RS17315
uniprot id: I5B742
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS17280
gene id: 879212:DESPODRAFT_RS17280
uniprot id: I5B736
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

879212:DESPODRAFT RS13530
gene id: 879212:DESPODRAFT_RS13530
uniprot id: I5B212
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

879212:DESPODRAFT RS02460
gene id: 879212:DESPODRAFT_RS02460
uniprot id: I5AZ32
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

879212:DESPODRAFT RS10735
gene id: 879212:DESPODRAFT_RS10735
uniprot id: I5B3I7
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS12865
gene id: 879212:DESPODRAFT_RS12865
uniprot id: I5B4P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

879212:DESPODRAFT RS02450
gene id: 879212:DESPODRAFT_RS02450
uniprot id: I5AZ30
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

879212:DESPODRAFT RS02160
gene id: 879212:DESPODRAFT_RS02160
uniprot id: I5AYX4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

879212:DESPODRAFT RS08240
gene id: 879212:DESPODRAFT_RS08240
uniprot id: I5B270
names: Similarity
messages: Belongs to the asparagine synthetase family.

879212:DESPODRAFT RS05680
gene id: 879212:DESPODRAFT_RS05680
uniprot id: I5B0U0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

879212:DESPODRAFT RS09630
gene id: 879212:DESPODRAFT_RS09630
uniprot id: I5B2Y5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

879212:DESPODRAFT RS07650
gene id: 879212:DESPODRAFT_RS07650
uniprot id: I5B1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

879212:DESPODRAFT RS01010
gene id: 879212:DESPODRAFT_RS01010
uniprot id: I5AYB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

879212:DESPODRAFT RS16135
gene id: 879212:DESPODRAFT_RS16135
uniprot id: I5B6G5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

879212:DESPODRAFT RS04590
gene id: 879212:DESPODRAFT_RS04590
uniprot id: I5B069
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

879212:DESPODRAFT RS03595
gene id: 879212:DESPODRAFT_RS03595
uniprot id: I5AZN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

879212:DESPODRAFT RS14215
gene id: 879212:DESPODRAFT_RS14215
uniprot id: I5B5E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

879212:DESPODRAFT RS14100
gene id: 879212:DESPODRAFT_RS14100
uniprot id: I5B5C6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

879212:DESPODRAFT RS01810
gene id: 879212:DESPODRAFT_RS01810
uniprot id: I5AYR1
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS02905
gene id: 879212:DESPODRAFT_RS02905
uniprot id: I5AZB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

879212:DESPODRAFT RS14425
gene id: 879212:DESPODRAFT_RS14425
uniprot id: I5B5I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

879212:DESPODRAFT RS10880
gene id: 879212:DESPODRAFT_RS10880
uniprot id: I5B212
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

879212:DESPODRAFT RS14240
gene id: 879212:DESPODRAFT_RS14240
uniprot id: I5B5F2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

879212:DESPODRAFT RS03535
gene id: 879212:DESPODRAFT_RS03535
uniprot id: I5AZM6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

879212:DESPODRAFT RS12680
gene id: 879212:DESPODRAFT_RS12680
uniprot id: I5B4L2
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

879212:DESPODRAFT RS02085
gene id: 879212:DESPODRAFT_RS02085
uniprot id: I5AYW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

879212:DESPODRAFT RS04420
gene id: 879212:DESPODRAFT_RS04420
uniprot id: I5B039
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS14305
gene id: 879212:DESPODRAFT_RS14305
uniprot id: I5B5G5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

879212:DESPODRAFT RS13310
gene id: 879212:DESPODRAFT_RS13310
uniprot id: I5B4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

879212:DESPODRAFT RS17065
gene id: 879212:DESPODRAFT_RS17065
uniprot id: I5B6Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

879212:DESPODRAFT RS12185
gene id: 879212:DESPODRAFT_RS12185
uniprot id: I5B4B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

879212:DESPODRAFT RS11210
gene id: 879212:DESPODRAFT_RS11210
uniprot id: I5B3T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

879212:DESPODRAFT RS15170
gene id: 879212:DESPODRAFT_RS15170
uniprot id: I5B5X9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

879212:DESPODRAFT RS09605
gene id: 879212:DESPODRAFT_RS09605
uniprot id: I5B2Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

879212:DESPODRAFT RS12180
gene id: 879212:DESPODRAFT_RS12180
uniprot id: I5B4B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

879212:DESPODRAFT RS02010
gene id: 879212:DESPODRAFT_RS02010
uniprot id: I5AYU5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

879212:DESPODRAFT RS09805
gene id: 879212:DESPODRAFT_RS09805
uniprot id: I5B317
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS17425
gene id: 879212:DESPODRAFT_RS17425
uniprot id: I5B764
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

879212:DESPODRAFT RS01175
gene id: 879212:DESPODRAFT_RS01175
uniprot id: I5AYE3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

879212:DESPODRAFT RS18920
gene id: 879212:DESPODRAFT_RS18920
uniprot id: I5B7I5
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

879212:DESPODRAFT RS04040
gene id: 879212:DESPODRAFT_RS04040
uniprot id: I5AZW6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

879212:DESPODRAFT RS08565
gene id: 879212:DESPODRAFT_RS08565
uniprot id: I5B2D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

879212:DESPODRAFT RS10970
gene id: 879212:DESPODRAFT_RS10970
uniprot id: I5B3N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

879212:DESPODRAFT RS14785
gene id: 879212:DESPODRAFT_RS14785
uniprot id: I5B5Q7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

879212:DESPODRAFT RS10295
gene id: 879212:DESPODRAFT_RS10295
uniprot id: I5B3A6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

879212:DESPODRAFT RS08890
gene id: 879212:DESPODRAFT_RS08890
uniprot id: I5B2J5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

879212:DESPODRAFT RS12695
gene id: 879212:DESPODRAFT_RS12695
uniprot id: I5B4L5
names: Similarity
messages: Belongs to the DEAD box helicase family.

879212:DESPODRAFT RS17790
gene id: 879212:DESPODRAFT_RS17790
uniprot id: I5B7C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

879212:DESPODRAFT RS01070
gene id: 879212:DESPODRAFT_RS01070
uniprot id: I5AYC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

879212:DESPODRAFT RS03020
gene id: 879212:DESPODRAFT_RS03020
uniprot id: I5AZD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

879212:DESPODRAFT RS10815
gene id: 879212:DESPODRAFT_RS10815
uniprot id: I5B3K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

879212:DESPODRAFT RS14060
gene id: 879212:DESPODRAFT_RS14060
uniprot id: I5B5B7
names: Similarity
messages: Belongs to the MEMO1 family.

879212:DESPODRAFT RS01300
gene id: 879212:DESPODRAFT_RS01300
uniprot id: I5AYG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS15705
gene id: 879212:DESPODRAFT_RS15705
uniprot id: I5B680
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

879212:DESPODRAFT RS13725
gene id: 879212:DESPODRAFT_RS13725
uniprot id: I5B553
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

879212:DESPODRAFT RS11285
gene id: 879212:DESPODRAFT_RS11285
uniprot id: I5B3U5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

879212:DESPODRAFT RS13590
gene id: 879212:DESPODRAFT_RS13590
uniprot id: I5B528
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

879212:DESPODRAFT RS15350
gene id: 879212:DESPODRAFT_RS15350
uniprot id: I5B614
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS08505
gene id: 879212:DESPODRAFT_RS08505
uniprot id: I5B2C2
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

879212:DESPODRAFT RS09980
gene id: 879212:DESPODRAFT_RS09980
uniprot id: I5B350
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879212:DESPODRAFT RS14345
gene id: 879212:DESPODRAFT_RS14345
uniprot id: I5B5H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

879212:DESPODRAFT RS00455
gene id: 879212:DESPODRAFT_RS00455
uniprot id: I5AY07
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

879212:DESPODRAFT RS12505
gene id: 879212:DESPODRAFT_RS12505
uniprot id: I5B4H7
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

879212:DESPODRAFT RS07635
gene id: 879212:DESPODRAFT_RS07635
uniprot id: I5B1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

879212:DESPODRAFT RS04635
gene id: 879212:DESPODRAFT_RS04635
uniprot id: I5B079
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

879212:DESPODRAFT RS05395
gene id: 879212:DESPODRAFT_RS05395
uniprot id: I5B0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

879212:DESPODRAFT RS18530
gene id: 879212:DESPODRAFT_RS18530
uniprot id: I5AZV0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

879212:DESPODRAFT RS07205
gene id: 879212:DESPODRAFT_RS07205
uniprot id: I5B1N1
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS17750
gene id: 879212:DESPODRAFT_RS17750
uniprot id: I5B7B7
names: Similarity
messages: Belongs to the HisA/HisF family.

879212:DESPODRAFT RS15890
gene id: 879212:DESPODRAFT_RS15890
uniprot id: I5B6B7
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

879212:DESPODRAFT RS16405
gene id: 879212:DESPODRAFT_RS16405
uniprot id: I5B6L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

879212:DESPODRAFT RS08410
gene id: 879212:DESPODRAFT_RS08410
uniprot id: I5B2A3
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

879212:DESPODRAFT RS05165
gene id: 879212:DESPODRAFT_RS05165
uniprot id: I5B0I9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

879212:DESPODRAFT RS02095
gene id: 879212:DESPODRAFT_RS02095
uniprot id: I5AYW2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

879212:DESPODRAFT RS04215
gene id: 879212:DESPODRAFT_RS04215
uniprot id: I5B001
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

879212:DESPODRAFT RS14720
gene id: 879212:DESPODRAFT_RS14720
uniprot id: I5B5P4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879212:DESPODRAFT RS00700
gene id: 879212:DESPODRAFT_RS00700
uniprot id: I5AY53
names: Similarity
messages: Belongs to the DtxR/MntR family.

879212:DESPODRAFT RS12115
gene id: 879212:DESPODRAFT_RS12115
uniprot id: I5B498
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

879212:DESPODRAFT RS06585
gene id: 879212:DESPODRAFT_RS06585
uniprot id: I5B1B6
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

879212:DESPODRAFT RS13460
gene id: 879212:DESPODRAFT_RS13460
uniprot id: I5B511
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

879212:DESPODRAFT RS08675
gene id: 879212:DESPODRAFT_RS08675
uniprot id: I5B2F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

879212:DESPODRAFT RS15320
gene id: 879212:DESPODRAFT_RS15320
uniprot id: I5B608
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

879212:DESPODRAFT RS08500
gene id: 879212:DESPODRAFT_RS08500
uniprot id: I5B2C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

879212:DESPODRAFT RS01805
gene id: 879212:DESPODRAFT_RS01805
uniprot id: I5AYR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS04150
gene id: 879212:DESPODRAFT_RS04150
uniprot id: I5AZY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS04290
gene id: 879212:DESPODRAFT_RS04290
uniprot id: I5B014
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

879212:DESPODRAFT RS09280
gene id: 879212:DESPODRAFT_RS09280
uniprot id: I5B2R9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

879212:DESPODRAFT RS18495
gene id: 879212:DESPODRAFT_RS18495
uniprot id: I5AYK0
names: Similarity
messages: Belongs to the serpin family.

879212:DESPODRAFT RS05300
gene id: 879212:DESPODRAFT_RS05300
uniprot id: I5B0L6
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS11725
gene id: 879212:DESPODRAFT_RS11725
uniprot id: I5B430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

879212:DESPODRAFT RS18090
gene id: 879212:DESPODRAFT_RS18090
uniprot id: I5B7I1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

879212:DESPODRAFT RS16275
gene id: 879212:DESPODRAFT_RS16275
uniprot id: I5B6J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

879212:DESPODRAFT RS12360
gene id: 879212:DESPODRAFT_RS12360
uniprot id: I5B4E9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

879212:DESPODRAFT RS01705
gene id: 879212:DESPODRAFT_RS01705
uniprot id: I5AYP0
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

879212:DESPODRAFT RS05845
gene id: 879212:DESPODRAFT_RS05845
uniprot id: I5B0X2
names: Similarity
messages: Belongs to the TrbI/VirB10 family.

879212:DESPODRAFT RS09590
gene id: 879212:DESPODRAFT_RS09590
uniprot id: I5B2X7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

879212:DESPODRAFT RS17600
gene id: 879212:DESPODRAFT_RS17600
uniprot id: I5B796
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

879212:DESPODRAFT RS16055
gene id: 879212:DESPODRAFT_RS16055
uniprot id: I5B6E9
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

879212:DESPODRAFT RS05360
gene id: 879212:DESPODRAFT_RS05360
uniprot id: I5B0M8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Belongs to the acylphosphatase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

879212:DESPODRAFT RS02310
gene id: 879212:DESPODRAFT_RS02310
uniprot id: I5AZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

879212:DESPODRAFT RS14495
gene id: 879212:DESPODRAFT_RS14495
uniprot id: I5B5K3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

879212:DESPODRAFT RS12845
gene id: 879212:DESPODRAFT_RS12845
uniprot id: I5B4P4
names: Similarity
messages: Belongs to the threonine synthase family.

879212:DESPODRAFT RS14225
gene id: 879212:DESPODRAFT_RS14225
uniprot id: I5B5E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

879212:DESPODRAFT RS14015
gene id: 879212:DESPODRAFT_RS14015
uniprot id: I5B5A8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

879212:DESPODRAFT RS04915
gene id: 879212:DESPODRAFT_RS04915
uniprot id: I5B0D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

879212:DESPODRAFT RS16550
gene id: 879212:DESPODRAFT_RS16550
uniprot id: I5B6P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

879212:DESPODRAFT RS12150
gene id: 879212:DESPODRAFT_RS12150
uniprot id: I5B4A5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

879212:DESPODRAFT RS13785
gene id: 879212:DESPODRAFT_RS13785
uniprot id: I5B564
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS03225
gene id: 879212:DESPODRAFT_RS03225
uniprot id: I5AZH3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

879212:DESPODRAFT RS07520
gene id: 879212:DESPODRAFT_RS07520
uniprot id: I5B1U0
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS02810
gene id: 879212:DESPODRAFT_RS02810
uniprot id: I5AZ98
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

879212:DESPODRAFT RS04115
gene id: 879212:DESPODRAFT_RS04115
uniprot id: I5AZY1
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS03370
gene id: 879212:DESPODRAFT_RS03370
uniprot id: I5AZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

879212:DESPODRAFT RS00600
gene id: 879212:DESPODRAFT_RS00600
uniprot id: I5AY33
names: Similarity
messages: Belongs to the PstS family.

879212:DESPODRAFT RS07385
gene id: 879212:DESPODRAFT_RS07385
uniprot id: I5B1R3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS12170
gene id: 879212:DESPODRAFT_RS12170
uniprot id: I5B4A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

879212:DESPODRAFT RS14370
gene id: 879212:DESPODRAFT_RS14370
uniprot id: I5B5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

879212:DESPODRAFT RS21140
gene id: 879212:DESPODRAFT_RS21140
uniprot id: I5B4L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

879212:DESPODRAFT RS11750
gene id: 879212:DESPODRAFT_RS11750
uniprot id: I5B434
names: Similarity
messages: Belongs to the NAD synthetase family.

879212:DESPODRAFT RS14530
gene id: 879212:DESPODRAFT_RS14530
uniprot id: I5B5L0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

879212:DESPODRAFT RS09875
gene id: 879212:DESPODRAFT_RS09875
uniprot id: I5B330
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

879212:DESPODRAFT RS16970
gene id: 879212:DESPODRAFT_RS16970
uniprot id: I5B6X6
names: Similarity
messages: Belongs to the peptidase S49 family.

879212:DESPODRAFT RS05135
gene id: 879212:DESPODRAFT_RS05135
uniprot id: I5B0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

879212:DESPODRAFT RS16940
gene id: 879212:DESPODRAFT_RS16940
uniprot id: I5B6X0
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

879212:DESPODRAFT RS11405
gene id: 879212:DESPODRAFT_RS11405
uniprot id: I5B3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS07790
gene id: 879212:DESPODRAFT_RS07790
uniprot id: I5B1Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

879212:DESPODRAFT RS06415
gene id: 879212:DESPODRAFT_RS06415
uniprot id: I5B184
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

879212:DESPODRAFT RS13235
gene id: 879212:DESPODRAFT_RS13235
uniprot id: I5B4W6
names: Similarity
messages: Belongs to the peptidase M1 family.

879212:DESPODRAFT RS13395
gene id: 879212:DESPODRAFT_RS13395
uniprot id: I5B4Z8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

879212:DESPODRAFT RS08585
gene id: 879212:DESPODRAFT_RS08585
uniprot id: I5B2D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

879212:DESPODRAFT RS09955
gene id: 879212:DESPODRAFT_RS09955
uniprot id: I5B345
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS07390
gene id: 879212:DESPODRAFT_RS07390
uniprot id: I5B1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS07975
gene id: 879212:DESPODRAFT_RS07975
uniprot id: I5B223
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

879212:DESPODRAFT RS15115
gene id: 879212:DESPODRAFT_RS15115
uniprot id: I5B5W9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS12915
gene id: 879212:DESPODRAFT_RS12915
uniprot id: I5B4Q8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS08260
gene id: 879212:DESPODRAFT_RS08260
uniprot id: I5B274
names: Similarity
messages: Belongs to the FemABX family.

879212:DESPODRAFT RS11555
gene id: 879212:DESPODRAFT_RS11555
uniprot id: I5B400
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

879212:DESPODRAFT RS00980
gene id: 879212:DESPODRAFT_RS00980
uniprot id: I5AYB0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

879212:DESPODRAFT RS17865
gene id: 879212:DESPODRAFT_RS17865
uniprot id: I5B7D9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

879212:DESPODRAFT RS11940
gene id: 879212:DESPODRAFT_RS11940
uniprot id: I5B469
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

879212:DESPODRAFT RS09745
gene id: 879212:DESPODRAFT_RS09745
uniprot id: I5B306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

879212:DESPODRAFT RS10830
gene id: 879212:DESPODRAFT_RS10830
uniprot id: I5B3K8
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS18655
gene id: 879212:DESPODRAFT_RS18655
uniprot id: I5B2Q5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

879212:DESPODRAFT RS15495
gene id: 879212:DESPODRAFT_RS15495
uniprot id: I5B640
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

879212:DESPODRAFT RS05835
gene id: 879212:DESPODRAFT_RS05835
uniprot id: I5B0X0
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

879212:DESPODRAFT RS17840
gene id: 879212:DESPODRAFT_RS17840
uniprot id: I5B7D4
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS05850
gene id: 879212:DESPODRAFT_RS05850
uniprot id: I5B0X3
names: Similarity
messages: Belongs to the type IA topoisomerase family.

879212:DESPODRAFT RS10975
gene id: 879212:DESPODRAFT_RS10975
uniprot id: I5B3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

879212:DESPODRAFT RS02245
gene id: 879212:DESPODRAFT_RS02245
uniprot id: I5AYY9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

879212:DESPODRAFT RS04850
gene id: 879212:DESPODRAFT_RS04850
uniprot id: I5B0C3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

879212:DESPODRAFT RS02675
gene id: 879212:DESPODRAFT_RS02675
uniprot id: I5AZ72
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

879212:DESPODRAFT RS04325
gene id: 879212:DESPODRAFT_RS04325
uniprot id: I5B021
names: Similarity
messages: Belongs to the phosphohexose mutase family.

879212:DESPODRAFT RS11065
gene id: 879212:DESPODRAFT_RS11065
uniprot id: I5B3Q3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

879212:DESPODRAFT RS00410
gene id: 879212:DESPODRAFT_RS00410
uniprot id: I5AXZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS12585
gene id: 879212:DESPODRAFT_RS12585
uniprot id: I5B4J3
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

879212:DESPODRAFT RS06530
gene id: 879212:DESPODRAFT_RS06530
uniprot id: I5B1A6
names: Subcellular Location Annotation
messages: Cytoplasm

879212:DESPODRAFT RS02430
gene id: 879212:DESPODRAFT_RS02430
uniprot id: I5AZ25
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

879212:DESPODRAFT RS05865
gene id: 879212:DESPODRAFT_RS05865
uniprot id: I5B0X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

879212:DESPODRAFT RS03230
gene id: 879212:DESPODRAFT_RS03230
uniprot id: I5AZH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS08875
gene id: 879212:DESPODRAFT_RS08875
uniprot id: I5B2J2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

879212:DESPODRAFT RS12700
gene id: 879212:DESPODRAFT_RS12700
uniprot id: I5B4L6
names: Similarity
messages: Belongs to the YggT family.

879212:DESPODRAFT RS05730
gene id: 879212:DESPODRAFT_RS05730
uniprot id: I5B0V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

879212:DESPODRAFT RS09495
gene id: 879212:DESPODRAFT_RS09495
uniprot id: I5B2V8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

879212:DESPODRAFT RS05725
gene id: 879212:DESPODRAFT_RS05725
uniprot id: I5B0U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

879212:DESPODRAFT RS06725
gene id: 879212:DESPODRAFT_RS06725
uniprot id: I5B1E0
names: Similarity
messages: Belongs to the diaminopimelate epimerase family.

879212:DESPODRAFT RS08450
gene id: 879212:DESPODRAFT_RS08450
uniprot id: I5B2B1
names: Similarity
messages: Belongs to the CutA family.

879212:DESPODRAFT RS13985
gene id: 879212:DESPODRAFT_RS13985
uniprot id: I5B5A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

879212:DESPODRAFT RS10695
gene id: 879212:DESPODRAFT_RS10695
uniprot id: I5B3I0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

879212:DESPODRAFT RS11680
gene id: 879212:DESPODRAFT_RS11680
uniprot id: I5B421
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

879212:DESPODRAFT RS02630
gene id: 879212:DESPODRAFT_RS02630
uniprot id: I5AZ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

879212:DESPODRAFT RS16065
gene id: 879212:DESPODRAFT_RS16065
uniprot id: I5B6F1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

879212:DESPODRAFT RS08855
gene id: 879212:DESPODRAFT_RS08855
uniprot id: I5B2I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

879212:DESPODRAFT RS12595
gene id: 879212:DESPODRAFT_RS12595
uniprot id: I5B4J5
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

879212:DESPODRAFT RS10920
gene id: 879212:DESPODRAFT_RS10920
uniprot id: I5B3M5
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

879212:DESPODRAFT RS15715
gene id: 879212:DESPODRAFT_RS15715
uniprot id: I5B682
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

879212:DESPODRAFT RS04330
gene id: 879212:DESPODRAFT_RS04330
uniprot id: I5B022
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS01685
gene id: 879212:DESPODRAFT_RS01685
uniprot id: I5AYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

879212:DESPODRAFT RS02655
gene id: 879212:DESPODRAFT_RS02655
uniprot id: I5AZ68
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

879212:DESPODRAFT RS02150
gene id: 879212:DESPODRAFT_RS02150
uniprot id: I5AYX2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

879212:DESPODRAFT RS12220
gene id: 879212:DESPODRAFT_RS12220
uniprot id: I5B4C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

879212:DESPODRAFT RS12055
gene id: 879212:DESPODRAFT_RS12055
uniprot id: I5B486
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

879212:DESPODRAFT RS12460
gene id: 879212:DESPODRAFT_RS12460
uniprot id: I5B4G8
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS02015
gene id: 879212:DESPODRAFT_RS02015
uniprot id: I5AYU6
names: Similarity
messages: Belongs to the YoeB family.

879212:DESPODRAFT RS17795
gene id: 879212:DESPODRAFT_RS17795
uniprot id: I5B7C5
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS07400
gene id: 879212:DESPODRAFT_RS07400
uniprot id: I5B1R6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

879212:DESPODRAFT RS12250
gene id: 879212:DESPODRAFT_RS12250
uniprot id: I5B4C7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

879212:DESPODRAFT RS14710
gene id: 879212:DESPODRAFT_RS14710
uniprot id: I5B5P2
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS03010
gene id: 879212:DESPODRAFT_RS03010
uniprot id: I5AZD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

879212:DESPODRAFT RS02910
gene id: 879212:DESPODRAFT_RS02910
uniprot id: I5AZB8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

879212:DESPODRAFT RS13775
gene id: 879212:DESPODRAFT_RS13775
uniprot id: I5B562
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

879212:DESPODRAFT RS01270
gene id: 879212:DESPODRAFT_RS01270
uniprot id: I5AYG0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

879212:DESPODRAFT RS13550
gene id: 879212:DESPODRAFT_RS13550
uniprot id: I5B521
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

879212:DESPODRAFT RS12575
gene id: 879212:DESPODRAFT_RS12575
uniprot id: I5B4J1
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

879212:DESPODRAFT RS02775
gene id: 879212:DESPODRAFT_RS02775
uniprot id: I5AZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

879212:DESPODRAFT RS14020
gene id: 879212:DESPODRAFT_RS14020
uniprot id: I5B5A9
names: Similarity
messages: Belongs to the bacterial flagellin family.

879212:DESPODRAFT RS15965
gene id: 879212:DESPODRAFT_RS15965
uniprot id: I5B6D1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

879212:DESPODRAFT RS18180
gene id: 879212:DESPODRAFT_RS18180
uniprot id: I5B7J8
names: Similarity
messages: Belongs to the universal stress protein A family.

879212:DESPODRAFT RS10385
gene id: 879212:DESPODRAFT_RS10385
uniprot id: I5B3C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

879212:DESPODRAFT RS17615
gene id: 879212:DESPODRAFT_RS17615
uniprot id: I5B799
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

879212:DESPODRAFT RS11385
gene id: 879212:DESPODRAFT_RS11385
uniprot id: I5B3W5
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS01385
gene id: 879212:DESPODRAFT_RS01385
uniprot id: I5AYI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

879212:DESPODRAFT RS08235
gene id: 879212:DESPODRAFT_RS08235
uniprot id: I5B269
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

879212:DESPODRAFT RS03045
gene id: 879212:DESPODRAFT_RS03045
uniprot id: I5AZE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

879212:DESPODRAFT RS16600
gene id: 879212:DESPODRAFT_RS16600
uniprot id: I5B6Q5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

879212:DESPODRAFT RS14140
gene id: 879212:DESPODRAFT_RS14140
uniprot id: I5B5D4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS11475
gene id: 879212:DESPODRAFT_RS11475
uniprot id: I5B3Y2
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS14430
gene id: 879212:DESPODRAFT_RS14430
uniprot id: I5B5J0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

879212:DESPODRAFT RS07820
gene id: 879212:DESPODRAFT_RS07820
uniprot id: I5B1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

879212:DESPODRAFT RS12175
gene id: 879212:DESPODRAFT_RS12175
uniprot id: I5B4B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

879212:DESPODRAFT RS08020
gene id: 879212:DESPODRAFT_RS08020
uniprot id: I5B232
names: Similarity
messages: Belongs to the LOG family.

879212:DESPODRAFT RS13130
gene id: 879212:DESPODRAFT_RS13130
uniprot id: I5B4U5
names: Similarity
messages: Belongs to the DtxR/MntR family.

879212:DESPODRAFT RS12235
gene id: 879212:DESPODRAFT_RS12235
uniprot id: I5B4C4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

879212:DESPODRAFT RS13280
gene id: 879212:DESPODRAFT_RS13280
uniprot id: I5B4X4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

879212:DESPODRAFT RS15405
gene id: 879212:DESPODRAFT_RS15405
uniprot id: I5B625
names: Similarity
messages: Belongs to the ParB family.

879212:DESPODRAFT RS17215
gene id: 879212:DESPODRAFT_RS17215
uniprot id: I5B724
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

879212:DESPODRAFT RS04840
gene id: 879212:DESPODRAFT_RS04840
uniprot id: I5B0C1
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

879212:DESPODRAFT RS08725
gene id: 879212:DESPODRAFT_RS08725
uniprot id: I5B2G4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

879212:DESPODRAFT RS09505
gene id: 879212:DESPODRAFT_RS09505
uniprot id: I5B2W0
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

879212:DESPODRAFT RS04060
gene id: 879212:DESPODRAFT_RS04060
uniprot id: I5AZX0
names: Similarity
messages: Belongs to the peptidase A31 family.

879212:DESPODRAFT RS17205
gene id: 879212:DESPODRAFT_RS17205
uniprot id: I5B722
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

879212:DESPODRAFT RS12705
gene id: 879212:DESPODRAFT_RS12705
uniprot id: I5B4L7
names: Subcellular Location Annotation
messages: Cytoplasm

879212:DESPODRAFT RS12715
gene id: 879212:DESPODRAFT_RS12715
uniprot id: I5B4L9
names: Similarity
messages: Belongs to the GSP E family.

879212:DESPODRAFT RS05985
gene id: 879212:DESPODRAFT_RS05985
uniprot id: I5B101
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

879212:DESPODRAFT RS13135
gene id: 879212:DESPODRAFT_RS13135
uniprot id: I5B4U6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

879212:DESPODRAFT RS13485
gene id: 879212:DESPODRAFT_RS13485
uniprot id: I5B516
names: Similarity
messages: Belongs to the polysaccharide synthase family.

879212:DESPODRAFT RS07810
gene id: 879212:DESPODRAFT_RS07810
uniprot id: I5B1Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

879212:DESPODRAFT RS01770
gene id: 879212:DESPODRAFT_RS01770
uniprot id: I5AYQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

879212:DESPODRAFT RS03890
gene id: 879212:DESPODRAFT_RS03890
uniprot id: I5AZT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

879212:DESPODRAFT RS01345
gene id: 879212:DESPODRAFT_RS01345
uniprot id: I5AYH5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

879212:DESPODRAFT RS10525
gene id: 879212:DESPODRAFT_RS10525
uniprot id: I5B3F1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

879212:DESPODRAFT RS08170
gene id: 879212:DESPODRAFT_RS08170
uniprot id: I5B256
names: Similarity
messages: Belongs to the asparagine synthetase family.

879212:DESPODRAFT RS06860
gene id: 879212:DESPODRAFT_RS06860
uniprot id: I5B1G6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

879212:DESPODRAFT RS17830
gene id: 879212:DESPODRAFT_RS17830
uniprot id: I5B7D2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879212:DESPODRAFT RS04000
gene id: 879212:DESPODRAFT_RS04000
uniprot id: I5AZV9
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

879212:DESPODRAFT RS10535
gene id: 879212:DESPODRAFT_RS10535
uniprot id: I5B3F3
names: Similarity
messages: Belongs to the ribF family.

879212:DESPODRAFT RS14010
gene id: 879212:DESPODRAFT_RS14010
uniprot id: I5B5A7
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

879212:DESPODRAFT RS03615
gene id: 879212:DESPODRAFT_RS03615
uniprot id: I5AZP0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

879212:DESPODRAFT RS13000
gene id: 879212:DESPODRAFT_RS13000
uniprot id: I5B4S5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

879212:DESPODRAFT RS11730
gene id: 879212:DESPODRAFT_RS11730
uniprot id: I5B431
names: Similarity
messages: Belongs to the GSP E family.

879212:DESPODRAFT RS14190
gene id: 879212:DESPODRAFT_RS14190
uniprot id: I5B5E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

879212:DESPODRAFT RS00750
gene id: 879212:DESPODRAFT_RS00750
uniprot id: I5AY63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

879212:DESPODRAFT RS10370
gene id: 879212:DESPODRAFT_RS10370
uniprot id: I5B3C0
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

879212:DESPODRAFT RS12440
gene id: 879212:DESPODRAFT_RS12440
uniprot id: I5B4G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

879212:DESPODRAFT RS12990
gene id: 879212:DESPODRAFT_RS12990
uniprot id: I5B4S3
names: Similarity
messages: Belongs to the elongation factor P family.

879212:DESPODRAFT RS11355
gene id: 879212:DESPODRAFT_RS11355
uniprot id: I5B3V9
names: Similarity
messages: Belongs to the Skp family.

879212:DESPODRAFT RS02855
gene id: 879212:DESPODRAFT_RS02855
uniprot id: I5AZA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

879212:DESPODRAFT RS14230
gene id: 879212:DESPODRAFT_RS14230
uniprot id: I5B5F0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

879212:DESPODRAFT RS06950
gene id: 879212:DESPODRAFT_RS06950
uniprot id: I5B1I4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

879212:DESPODRAFT RS01275
gene id: 879212:DESPODRAFT_RS01275
uniprot id: I5AYG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

879212:DESPODRAFT RS01580
gene id: 879212:DESPODRAFT_RS01580
uniprot id: I5AYL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

879212:DESPODRAFT RS00710
gene id: 879212:DESPODRAFT_RS00710
uniprot id: I5AY55
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS17770
gene id: 879212:DESPODRAFT_RS17770
uniprot id: I5B7C1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

879212:DESPODRAFT RS08210
gene id: 879212:DESPODRAFT_RS08210
uniprot id: I5B264
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS09510
gene id: 879212:DESPODRAFT_RS09510
uniprot id: I5B2W1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

879212:DESPODRAFT RS17020
gene id: 879212:DESPODRAFT_RS17020
uniprot id: I5B6Y6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

879212:DESPODRAFT RS03900
gene id: 879212:DESPODRAFT_RS03900
uniprot id: I5AZU0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

879212:DESPODRAFT RS11160
gene id: 879212:DESPODRAFT_RS11160
uniprot id: I5B3S1
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

879212:DESPODRAFT RS14040
gene id: 879212:DESPODRAFT_RS14040
uniprot id: I5B5B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

879212:DESPODRAFT RS10780
gene id: 879212:DESPODRAFT_RS10780
uniprot id: I5B3J7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

879212:DESPODRAFT RS03030
gene id: 879212:DESPODRAFT_RS03030
uniprot id: I5AZD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

879212:DESPODRAFT RS11710
gene id: 879212:DESPODRAFT_RS11710
uniprot id: I5B427
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

879212:DESPODRAFT RS02695
gene id: 879212:DESPODRAFT_RS02695
uniprot id: I5AZ76
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

879212:DESPODRAFT RS09060
gene id: 879212:DESPODRAFT_RS09060
uniprot id: I5B2M7
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

879212:DESPODRAFT RS12530
gene id: 879212:DESPODRAFT_RS12530
uniprot id: I5B4I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

879212:DESPODRAFT RS00435
gene id: 879212:DESPODRAFT_RS00435
uniprot id: I5AY02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

879212:DESPODRAFT RS01350
gene id: 879212:DESPODRAFT_RS01350
uniprot id: I5AYH7
names: Subcellular Location Annotation
messages: Cytoplasm

879212:DESPODRAFT RS07950
gene id: 879212:DESPODRAFT_RS07950
uniprot id: I5B218
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

879212:DESPODRAFT RS07075
gene id: 879212:DESPODRAFT_RS07075
uniprot id: I5B1K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

879212:DESPODRAFT RS06200
gene id: 879212:DESPODRAFT_RS06200
uniprot id: I5B143
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

879212:DESPODRAFT RS13625
gene id: 879212:DESPODRAFT_RS13625
uniprot id: I5B535
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS04730
gene id: 879212:DESPODRAFT_RS04730
uniprot id: I5B097
names: Similarity
messages: Belongs to the AlaDH/PNT family.

879212:DESPODRAFT RS11800
gene id: 879212:DESPODRAFT_RS11800
uniprot id: I5B444
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

879212:DESPODRAFT RS05215
gene id: 879212:DESPODRAFT_RS05215
uniprot id: I5B0J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

879212:DESPODRAFT RS07310
gene id: 879212:DESPODRAFT_RS07310
uniprot id: I5B1Q1
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

879212:DESPODRAFT RS03830
gene id: 879212:DESPODRAFT_RS03830
uniprot id: I5AZS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

879212:DESPODRAFT RS17540
gene id: 879212:DESPODRAFT_RS17540
uniprot id: I5B784
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

879212:DESPODRAFT RS10000
gene id: 879212:DESPODRAFT_RS10000
uniprot id: I5B354
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS13450
gene id: 879212:DESPODRAFT_RS13450
uniprot id: I5B509
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

879212:DESPODRAFT RS17955
gene id: 879212:DESPODRAFT_RS17955
uniprot id: I5B7F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

879212:DESPODRAFT RS12930
gene id: 879212:DESPODRAFT_RS12930
uniprot id: I5B4R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

879212:DESPODRAFT RS08495
gene id: 879212:DESPODRAFT_RS08495
uniprot id: I5B2C0
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS02135
gene id: 879212:DESPODRAFT_RS02135
uniprot id: I5AYW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

879212:DESPODRAFT RS11890
gene id: 879212:DESPODRAFT_RS11890
uniprot id: I5B460
names: Similarity
messages: Belongs to the universal stress protein A family.

879212:DESPODRAFT RS11495
gene id: 879212:DESPODRAFT_RS11495
uniprot id: I5B3Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

879212:DESPODRAFT RS14085
gene id: 879212:DESPODRAFT_RS14085
uniprot id: I5B5C2
names: Cofactor
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

879212:DESPODRAFT RS14030
gene id: 879212:DESPODRAFT_RS14030
uniprot id: I5B5B1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

879212:DESPODRAFT RS14525
gene id: 879212:DESPODRAFT_RS14525
uniprot id: I5B5K9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

879212:DESPODRAFT RS15355
gene id: 879212:DESPODRAFT_RS15355
uniprot id: I5B615
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

879212:DESPODRAFT RS14185
gene id: 879212:DESPODRAFT_RS14185
uniprot id: I5B5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

879212:DESPODRAFT RS16860
gene id: 879212:DESPODRAFT_RS16860
uniprot id: I5B6V4
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

879212:DESPODRAFT RS10610
gene id: 879212:DESPODRAFT_RS10610
uniprot id: I5B3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

879212:DESPODRAFT RS10530
gene id: 879212:DESPODRAFT_RS10530
uniprot id: I5B3F2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

879212:DESPODRAFT RS00730
gene id: 879212:DESPODRAFT_RS00730
uniprot id: I5AY59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

879212:DESPODRAFT RS14545
gene id: 879212:DESPODRAFT_RS14545
uniprot id: I5B5L3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

879212:DESPODRAFT RS03555
gene id: 879212:DESPODRAFT_RS03555
uniprot id: I5AZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

879212:DESPODRAFT RS13710
gene id: 879212:DESPODRAFT_RS13710
uniprot id: I5B550
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

879212:DESPODRAFT RS02335
gene id: 879212:DESPODRAFT_RS02335
uniprot id: I5AZ07
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS01305
gene id: 879212:DESPODRAFT_RS01305
uniprot id: I5AYG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

879212:DESPODRAFT RS00620
gene id: 879212:DESPODRAFT_RS00620
uniprot id: I5AY37
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

879212:DESPODRAFT RS09170
gene id: 879212:DESPODRAFT_RS09170
uniprot id: I5B2P5
names: Subcellular Location Annotation
messages: Membrane

879212:DESPODRAFT RS05285
gene id: 879212:DESPODRAFT_RS05285
uniprot id: I5B0L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

879212:DESPODRAFT RS05815
gene id: 879212:DESPODRAFT_RS05815
uniprot id: I5B0W5
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

879212:DESPODRAFT RS14905
gene id: 879212:DESPODRAFT_RS14905
uniprot id: I5B5T0
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

879212:DESPODRAFT RS13595
gene id: 879212:DESPODRAFT_RS13595
uniprot id: I5B529
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

879212:DESPODRAFT RS08630
gene id: 879212:DESPODRAFT_RS08630
uniprot id: I5B2E6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS08000
gene id: 879212:DESPODRAFT_RS08000
uniprot id: I5B228
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

879212:DESPODRAFT RS10795
gene id: 879212:DESPODRAFT_RS10795
uniprot id: I5B3K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

879212:DESPODRAFT RS02950
gene id: 879212:DESPODRAFT_RS02950
uniprot id: I5AZC5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

879212:DESPODRAFT RS16075
gene id: 879212:DESPODRAFT_RS16075
uniprot id: I5B6F3
names: Similarity
messages: Belongs to the UPF0045 family.

879212:DESPODRAFT RS13565
gene id: 879212:DESPODRAFT_RS13565
uniprot id: I5B523
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

879212:DESPODRAFT RS01675
gene id: 879212:DESPODRAFT_RS01675
uniprot id: I5AYN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

879212:DESPODRAFT RS02090
gene id: 879212:DESPODRAFT_RS02090
uniprot id: I5AYW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm