875328:JDM601 RS23365
gene id: 875328:JDM601_RS23365
uniprot id: F5YTC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

875328:JDM601 RS16565
gene id: 875328:JDM601_RS16565
uniprot id: F5YXV2
names: Similarity
messages: Belongs to the peptidase S49 family.

875328:JDM601 RS19285
gene id: 875328:JDM601_RS19285
uniprot id: F5YRS1
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

875328:JDM601 RS02695
gene id: 875328:JDM601_RS02695
uniprot id: F5Z1P4
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

875328:JDM601 RS05880
gene id: 875328:JDM601_RS05880
uniprot id: F5YVB4
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS14385
gene id: 875328:JDM601_RS14385
uniprot id: F5Z085
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

875328:JDM601 RS12375
gene id: 875328:JDM601_RS12375
uniprot id: F5YW48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

875328:JDM601 RS18755
gene id: 875328:JDM601_RS18755
uniprot id: F5Z372
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

875328:JDM601 RS09245
gene id: 875328:JDM601_RS09245
uniprot id: F5Z2P1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

875328:JDM601 RS07550
gene id: 875328:JDM601_RS07550
uniprot id: F5YYB3
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS06525
gene id: 875328:JDM601_RS06525
uniprot id: F5YWL1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

875328:JDM601 RS09175
gene id: 875328:JDM601_RS09175
uniprot id: F5Z2M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

875328:JDM601 RS17165
gene id: 875328:JDM601_RS17165
uniprot id: F5YZJ9
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS05180
gene id: 875328:JDM601_RS05180
uniprot id: F5YUG1
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS19970
gene id: 875328:JDM601_RS19970
uniprot id: F5YT11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

875328:JDM601 RS03450
gene id: 875328:JDM601_RS03450
uniprot id: F5Z3G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

875328:JDM601 RS16280
gene id: 875328:JDM601_RS16280
uniprot id: F5YXP4
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

875328:JDM601 RS01615
gene id: 875328:JDM601_RS01615
uniprot id: F5YZP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

875328:JDM601 RS04670
gene id: 875328:JDM601_RS04670
uniprot id: F5YT98
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS10050
gene id: 875328:JDM601_RS10050
uniprot id: F5YS31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS09705
gene id: 875328:JDM601_RS09705
uniprot id: F5Z3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

875328:JDM601 RS18875
gene id: 875328:JDM601_RS18875
uniprot id: F5Z396
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS17860
gene id: 875328:JDM601_RS17860
uniprot id: F5Z1B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

875328:JDM601 RS06220
gene id: 875328:JDM601_RS06220
uniprot id: F5YVY9
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS08510
gene id: 875328:JDM601_RS08510
uniprot id: F5Z0W8
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS00010
gene id: 875328:JDM601_RS00010
uniprot id: F5YWA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

875328:JDM601 RS12345
gene id: 875328:JDM601_RS12345
uniprot id: F5YW42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS19925
gene id: 875328:JDM601_RS19925
uniprot id: F5YT01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS02715
gene id: 875328:JDM601_RS02715
uniprot id: F5Z1P8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

875328:JDM601 RS01440
gene id: 875328:JDM601_RS01440
uniprot id: F5YYX4
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

875328:JDM601 RS08720
gene id: 875328:JDM601_RS08720
uniprot id: F5Z110
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

875328:JDM601 RS12785
gene id: 875328:JDM601_RS12785
uniprot id: F5YWT7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS16675
gene id: 875328:JDM601_RS16675
uniprot id: F5YYL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

875328:JDM601 RS13825
gene id: 875328:JDM601_RS13825
uniprot id: F5YZ85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

875328:JDM601 RS19190
gene id: 875328:JDM601_RS19190
uniprot id: F5YRQ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS08250
gene id: 875328:JDM601_RS08250
uniprot id: F5Z026
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

875328:JDM601 RS06510
gene id: 875328:JDM601_RS06510
uniprot id: F5YWK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

875328:JDM601 RS05480
gene id: 875328:JDM601_RS05480
uniprot id: F5YUM2
names: Subcellular Location Annotation
messages: Cell membrane

875328:JDM601 RS03425
gene id: 875328:JDM601_RS03425
uniprot id: F5Z3G4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS18400
gene id: 875328:JDM601_RS18400
uniprot id: F5Z2B2
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

875328:JDM601 RS20265
gene id: 875328:JDM601_RS20265
uniprot id: F5YTM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS02760
gene id: 875328:JDM601_RS02760
uniprot id: F5Z2E6
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS10235
gene id: 875328:JDM601_RS10235
uniprot id: F5YS69
names: Similarity
messages: Belongs to the CFA/CMAS family.

875328:JDM601 RS00085
gene id: 875328:JDM601_RS00085
uniprot id: F5YWB4
names: Subcellular Location Annotation
messages: Cell membrane

875328:JDM601 RS05465
gene id: 875328:JDM601_RS05465
uniprot id: F5YUL9
names: Similarity
messages: Belongs to the citrate synthase family.

875328:JDM601 RS14425
gene id: 875328:JDM601_RS14425
uniprot id: F5Z093
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS20670
gene id: 875328:JDM601_RS20670
uniprot id: F5YUB8
names: Similarity
messages: Belongs to the MmpS family.

875328:JDM601 RS05190
gene id: 875328:JDM601_RS05190
uniprot id: F5YUG3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

875328:JDM601 RS10755
gene id: 875328:JDM601_RS10755
uniprot id: F5YTD8
names: Similarity
messages: Belongs to the TrpC family.

875328:JDM601 RS10595
gene id: 875328:JDM601_RS10595
uniprot id: F5YSV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS11495
gene id: 875328:JDM601_RS11495
uniprot id: F5YUQ4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

875328:JDM601 RS04565
gene id: 875328:JDM601_RS04565
uniprot id: F5YT77
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

875328:JDM601 RS08825
gene id: 875328:JDM601_RS08825
uniprot id: F5Z1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

875328:JDM601 RS00190
gene id: 875328:JDM601_RS00190
uniprot id: F5YWD7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

875328:JDM601 RS14050
gene id: 875328:JDM601_RS14050
uniprot id: F5YZD2
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

875328:JDM601 RS03460
gene id: 875328:JDM601_RS03460
uniprot id: F5Z3H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

875328:JDM601 RS14435
gene id: 875328:JDM601_RS14435
uniprot id: F5Z095
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

875328:JDM601 RS00255
gene id: 875328:JDM601_RS00255
uniprot id: F5YWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

875328:JDM601 RS06490
gene id: 875328:JDM601_RS06490
uniprot id: F5YWK4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

875328:JDM601 RS12755
gene id: 875328:JDM601_RS12755
uniprot id: F5YWS9
names: Similarity
messages: Belongs to the peptidase M16 family.

875328:JDM601 RS17075
gene id: 875328:JDM601_RS17075
uniprot id: F5YZI0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS02575
gene id: 875328:JDM601_RS02575
uniprot id: F5Z1L9
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

875328:JDM601 RS12200
gene id: 875328:JDM601_RS12200
uniprot id: F5YVK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS02495
gene id: 875328:JDM601_RS02495
uniprot id: F5Z1K3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

875328:JDM601 RS03620
gene id: 875328:JDM601_RS03620
uniprot id: F5YRU8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS06690
gene id: 875328:JDM601_RS06690
uniprot id: F5YWN9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS18570
gene id: 875328:JDM601_RS18570
uniprot id: F5Z334
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS18605
gene id: 875328:JDM601_RS18605
uniprot id: F5Z341
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

875328:JDM601 RS17550
gene id: 875328:JDM601_RS17550
uniprot id: F5Z0G4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS07335
gene id: 875328:JDM601_RS07335
uniprot id: F5YY69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

875328:JDM601 RS12495
gene id: 875328:JDM601_RS12495
uniprot id: F5YW72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

875328:JDM601 RS21635
gene id: 875328:JDM601_RS21635
uniprot id: F5YVT0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

875328:JDM601 RS15570
gene id: 875328:JDM601_RS15570
uniprot id: F5Z2Y5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

875328:JDM601 RS09985
gene id: 875328:JDM601_RS09985
uniprot id: F5YS18
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

875328:JDM601 RS07325
gene id: 875328:JDM601_RS07325
uniprot id: F5YY67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

875328:JDM601 RS13170
gene id: 875328:JDM601_RS13170
uniprot id: F5YXH9
names: Similarity
messages: Belongs to the UPF0102 family.

875328:JDM601 RS06565
gene id: 875328:JDM601_RS06565
uniprot id: F5YWL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: In the C-terminal section; belongs to the ATPase delta chain family.
messages: In the N-terminal section; belongs to the ATPase B chain family.
messages: Membrane
messages: This fusion protein includes a component of the F(0) channel (subunit b) and of the F(1) subunit (subunit delta). Two copies of subunit b and one of delta together form the peripheral 'stator' stalk which links F(1) to F(0).
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

875328:JDM601 RS09690
gene id: 875328:JDM601_RS09690
uniprot id: F5Z3L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

875328:JDM601 RS02190
gene id: 875328:JDM601_RS02190
uniprot id: F5Z0Q1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS09405
gene id: 875328:JDM601_RS09405
uniprot id: F5Z2S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

875328:JDM601 RS13520
gene id: 875328:JDM601_RS13520
uniprot id: F5YYD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

875328:JDM601 RS08565
gene id: 875328:JDM601_RS08565
uniprot id: F5Z0Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

875328:JDM601 RS05085
gene id: 875328:JDM601_RS05085
uniprot id: F5YTY3
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

875328:JDM601 RS04805
gene id: 875328:JDM601_RS04805
uniprot id: F5YTT0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

875328:JDM601 RS12775
gene id: 875328:JDM601_RS12775
uniprot id: F5YWT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS04895
gene id: 875328:JDM601_RS04895
uniprot id: F5YTU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

875328:JDM601 RS03395
gene id: 875328:JDM601_RS03395
uniprot id: F5Z3F7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

875328:JDM601 RS06755
gene id: 875328:JDM601_RS06755
uniprot id: F5YWQ2
names: Similarity
messages: Belongs to the peptidase S58 family.

875328:JDM601 RS13225
gene id: 875328:JDM601_RS13225
uniprot id: A0A1A2F1W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

875328:JDM601 RS00930
gene id: 875328:JDM601_RS00930
uniprot id: F5YXY7
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

875328:JDM601 RS21255
gene id: 875328:JDM601_RS21255
uniprot id: F5YV48
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS07870
gene id: 875328:JDM601_RS07870
uniprot id: F5YZ64
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS13195
gene id: 875328:JDM601_RS13195
uniprot id: F5YXI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

875328:JDM601 RS17905
gene id: 875328:JDM601_RS17905
uniprot id: F5Z1C5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

875328:JDM601 RS07240
gene id: 875328:JDM601_RS07240
uniprot id: F5YY52
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

875328:JDM601 RS07985
gene id: 875328:JDM601_RS07985
uniprot id: F5YZX4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

875328:JDM601 RS05175
gene id: 875328:JDM601_RS05175
uniprot id: F5YU00
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

875328:JDM601 RS11210
gene id: 875328:JDM601_RS11210
uniprot id: F5YU35
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS09980
gene id: 875328:JDM601_RS09980
uniprot id: F5YS17
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS00405
gene id: 875328:JDM601_RS00405
uniprot id: F5YWZ4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

875328:JDM601 RS20080
gene id: 875328:JDM601_RS20080
uniprot id: F5YT31
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

875328:JDM601 RS21480
gene id: 875328:JDM601_RS21480
uniprot id: F5YVP8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

875328:JDM601 RS13145
gene id: 875328:JDM601_RS13145
uniprot id: F5YXH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

875328:JDM601 RS04900
gene id: 875328:JDM601_RS04900
uniprot id: F5YTV0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS02085
gene id: 875328:JDM601_RS02085
uniprot id: F5Z0M9
names: Similarity
messages: Belongs to the AAA ATPase family.

875328:JDM601 RS10815
gene id: 875328:JDM601_RS10815
uniprot id: F5YTF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

875328:JDM601 RS11180
gene id: 875328:JDM601_RS11180
uniprot id: F5YU29
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

875328:JDM601 RS07365
gene id: 875328:JDM601_RS07365
uniprot id: F5YY75
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

875328:JDM601 RS09440
gene id: 875328:JDM601_RS09440
uniprot id: F5Z2S8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

875328:JDM601 RS20310
gene id: 875328:JDM601_RS20310
uniprot id: F5YTN4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

875328:JDM601 RS03165
gene id: 875328:JDM601_RS03165
uniprot id: F5Z3B3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS06520
gene id: 875328:JDM601_RS06520
uniprot id: F5YWL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

875328:JDM601 RS13230
gene id: 875328:JDM601_RS13230
uniprot id: F5YXJ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

875328:JDM601 RS09160
gene id: 875328:JDM601_RS09160
uniprot id: F5Z2M4
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS14415
gene id: 875328:JDM601_RS14415
uniprot id: F5Z091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

875328:JDM601 RS10055
gene id: 875328:JDM601_RS10055
uniprot id: F5YS32
names: Similarity
messages: Belongs to the UPF0045 family.

875328:JDM601 RS13070
gene id: 875328:JDM601_RS13070
uniprot id: F5YXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

875328:JDM601 RS20750
gene id: 875328:JDM601_RS20750
uniprot id: F5YUD5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

875328:JDM601 RS17945
gene id: 875328:JDM601_RS17945
uniprot id: F5Z1D3
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

875328:JDM601 RS00800
gene id: 875328:JDM601_RS00800
uniprot id: F5YXW1
names: Similarity
messages: Belongs to the peptidase M13 family.

875328:JDM601 RS16090
gene id: 875328:JDM601_RS16090
uniprot id: F5Z3Y1
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

875328:JDM601 RS15440
gene id: 875328:JDM601_RS15440
uniprot id: F5Z2V8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

875328:JDM601 RS12420
gene id: 875328:JDM601_RS12420
uniprot id: F5YW57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS19985
gene id: 875328:JDM601_RS19985
uniprot id: F5YT14
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

875328:JDM601 RS01640
gene id: 875328:JDM601_RS01640
uniprot id: F5YZQ1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

875328:JDM601 RS12300
gene id: 875328:JDM601_RS12300
uniprot id: F5YW33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

875328:JDM601 RS12790
gene id: 875328:JDM601_RS12790
uniprot id: F5YWT8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS20995
gene id: 875328:JDM601_RS20995
uniprot id: F5YUZ7
names: Similarity
messages: Belongs to the peptidase S33 family.

875328:JDM601 RS16250
gene id: 875328:JDM601_RS16250
uniprot id: F5YXN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

875328:JDM601 RS05790
gene id: 875328:JDM601_RS05790
uniprot id: F5YV96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS17000
gene id: 875328:JDM601_RS17000
uniprot id: F5YZG6
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS16625
gene id: 875328:JDM601_RS16625
uniprot id: F5YYK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

875328:JDM601 RS08630
gene id: 875328:JDM601_RS08630
uniprot id: F5Z0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

875328:JDM601 RS00915
gene id: 875328:JDM601_RS00915
uniprot id: F5YXY4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS15720
gene id: 875328:JDM601_RS15720
uniprot id: F5Z318
names: Similarity
messages: Belongs to the phosphohexose mutase family.

875328:JDM601 RS18225
gene id: 875328:JDM601_RS18225
uniprot id: F5Z279
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS02625
gene id: 875328:JDM601_RS02625
uniprot id: F5Z1N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

875328:JDM601 RS00155
gene id: 875328:JDM601_RS00155
uniprot id: F5YWC8
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.
messages: Belongs to the FMO family.

875328:JDM601 RS01120
gene id: 875328:JDM601_RS01120
uniprot id: F5YY26
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS17480
gene id: 875328:JDM601_RS17480
uniprot id: F5Z0F0
names: Similarity
messages: Belongs to the HIBADH-related family.

875328:JDM601 RS17865
gene id: 875328:JDM601_RS17865
uniprot id: F5Z1B7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

875328:JDM601 RS14410
gene id: 875328:JDM601_RS14410
uniprot id: F5Z090
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

875328:JDM601 RS12240
gene id: 875328:JDM601_RS12240
uniprot id: F5YW21
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

875328:JDM601 RS05160
gene id: 875328:JDM601_RS05160
uniprot id: F5YTZ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS13205
gene id: 875328:JDM601_RS13205
uniprot id: F5YXI6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

875328:JDM601 RS14305
gene id: 875328:JDM601_RS14305
uniprot id: F5Z069
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

875328:JDM601 RS11220
gene id: 875328:JDM601_RS11220
uniprot id: F5YU37
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS02240
gene id: 875328:JDM601_RS02240
uniprot id: F5Z0R1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

875328:JDM601 RS17080
gene id: 875328:JDM601_RS17080
uniprot id: F5YZI1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS02150
gene id: 875328:JDM601_RS02150
uniprot id: F5Z0P3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

875328:JDM601 RS11590
gene id: 875328:JDM601_RS11590
uniprot id: F5YUS4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS03640
gene id: 875328:JDM601_RS03640
uniprot id: F5YRV2
names: Similarity
messages: Belongs to the TPP enzyme family.

875328:JDM601 RS19640
gene id: 875328:JDM601_RS19640
uniprot id: F5YSD5
names: Subcellular Location Annotation
messages: Cytoplasm

875328:JDM601 RS15780
gene id: 875328:JDM601_RS15780
uniprot id: F5Z3R8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

875328:JDM601 RS14280
gene id: 875328:JDM601_RS14280
uniprot id: F5Z064
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

875328:JDM601 RS03405
gene id: 875328:JDM601_RS03405
uniprot id: F5Z3F9
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

875328:JDM601 RS04390
gene id: 875328:JDM601_RS04390
uniprot id: F5YT42
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS00185
gene id: 875328:JDM601_RS00185
uniprot id: F5YWD6
names: Similarity
messages: Belongs to the pirin family.

875328:JDM601 RS06420
gene id: 875328:JDM601_RS06420
uniprot id: F5YWJ1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

875328:JDM601 RS17065
gene id: 875328:JDM601_RS17065
uniprot id: F5YZH8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS10615
gene id: 875328:JDM601_RS10615
uniprot id: F5YSV4
names: Subcellular Location Annotation
messages: Cytoplasm

875328:JDM601 RS12940
gene id: 875328:JDM601_RS12940
uniprot id: F5YWW8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

875328:JDM601 RS07105
gene id: 875328:JDM601_RS07105
uniprot id: F5YXD4
names: Similarity
messages: Belongs to the AccD/PCCB family.

875328:JDM601 RS16635
gene id: 875328:JDM601_RS16635
uniprot id: F5YYK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

875328:JDM601 RS13720
gene id: 875328:JDM601_RS13720
uniprot id: F5YYH5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

875328:JDM601 RS12220
gene id: 875328:JDM601_RS12220
uniprot id: F5YW17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

875328:JDM601 RS20840
gene id: 875328:JDM601_RS20840
uniprot id: F5YUF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

875328:JDM601 RS14060
gene id: 875328:JDM601_RS14060
uniprot id: F5YZD4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS13400
gene id: 875328:JDM601_RS13400
uniprot id: F5YXM6
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

875328:JDM601 RS16240
gene id: 875328:JDM601_RS16240
uniprot id: F5YXN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

875328:JDM601 RS19965
gene id: 875328:JDM601_RS19965
uniprot id: F5YT10
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

875328:JDM601 RS10745
gene id: 875328:JDM601_RS10745
uniprot id: F5YTD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

875328:JDM601 RS17015
gene id: 875328:JDM601_RS17015
uniprot id: F5YZG9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

875328:JDM601 RS03045
gene id: 875328:JDM601_RS03045
uniprot id: F5Z2K2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

875328:JDM601 RS19460
gene id: 875328:JDM601_RS19460
uniprot id: F5YSA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

875328:JDM601 RS04990
gene id: 875328:JDM601_RS04990
uniprot id: F5YTW5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

875328:JDM601 RS04735
gene id: 875328:JDM601_RS04735
uniprot id: F5YTB2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

875328:JDM601 RS13060
gene id: 875328:JDM601_RS13060
uniprot id: F5YXF7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

875328:JDM601 RS08365
gene id: 875328:JDM601_RS08365
uniprot id: F5Z0T8
names: Similarity
messages: Belongs to the CdaR family.

875328:JDM601 RS10790
gene id: 875328:JDM601_RS10790
uniprot id: F5YTE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS05310
gene id: 875328:JDM601_RS05310
uniprot id: F5YUI7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

875328:JDM601 RS18580
gene id: 875328:JDM601_RS18580
uniprot id: F5Z336
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS02475
gene id: 875328:JDM601_RS02475
uniprot id: F5Z1J9
names: Similarity
messages: Belongs to the UPF0336 family.

875328:JDM601 RS04010
gene id: 875328:JDM601_RS04010
uniprot id: F5YSF9
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

875328:JDM601 RS17655
gene id: 875328:JDM601_RS17655
uniprot id: F5Z0I5
names: Similarity
messages: Belongs to the PstS family.

875328:JDM601 RS09285
gene id: 875328:JDM601_RS09285
uniprot id: F5Z2P9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS04680
gene id: 875328:JDM601_RS04680
uniprot id: F5YTA0
names: Similarity
messages: Belongs to the AccD/PCCB family.

875328:JDM601 RS09335
gene id: 875328:JDM601_RS09335
uniprot id: F5Z2Q9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

875328:JDM601 RS15985
gene id: 875328:JDM601_RS15985
uniprot id: F5Z3V9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

875328:JDM601 RS09825
gene id: 875328:JDM601_RS09825
uniprot id: F5Z3P5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

875328:JDM601 RS05255
gene id: 875328:JDM601_RS05255
uniprot id: F5YUH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS03370
gene id: 875328:JDM601_RS03370
uniprot id: F5Z3F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

875328:JDM601 RS09085
gene id: 875328:JDM601_RS09085
uniprot id: F5Z1X0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

875328:JDM601 RS08840
gene id: 875328:JDM601_RS08840
uniprot id: F5Z1S3
names: Similarity
messages: Belongs to the YggT family.

875328:JDM601 RS09480
gene id: 875328:JDM601_RS09480
uniprot id: F5Z2T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

875328:JDM601 RS03240
gene id: 875328:JDM601_RS03240
uniprot id: F5Z3C8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS11440
gene id: 875328:JDM601_RS11440
uniprot id: F5YUP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

875328:JDM601 RS03445
gene id: 875328:JDM601_RS03445
uniprot id: F5Z3G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

875328:JDM601 RS07215
gene id: 875328:JDM601_RS07215
uniprot id: F5YY47
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

875328:JDM601 RS06120
gene id: 875328:JDM601_RS06120
uniprot id: F5YVW9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family. Kgd subfamily.

875328:JDM601 RS17500
gene id: 875328:JDM601_RS17500
uniprot id: F5Z0F4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

875328:JDM601 RS05060
gene id: 875328:JDM601_RS05060
uniprot id: F5YTX9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS11620
gene id: 875328:JDM601_RS11620
uniprot id: F5YUT0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS00775
gene id: 875328:JDM601_RS00775
uniprot id: F5YX69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS15920
gene id: 875328:JDM601_RS15920
uniprot id: F5Z3U6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

875328:JDM601 RS12905
gene id: 875328:JDM601_RS12905
uniprot id: F5YWW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

875328:JDM601 RS02545
gene id: 875328:JDM601_RS02545
uniprot id: F5Z1L3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

875328:JDM601 RS02145
gene id: 875328:JDM601_RS02145
uniprot id: F5Z0P2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

875328:JDM601 RS09715
gene id: 875328:JDM601_RS09715
uniprot id: F5Z3M1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

875328:JDM601 RS05895
gene id: 875328:JDM601_RS05895
uniprot id: F5YVB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

875328:JDM601 RS08545
gene id: 875328:JDM601_RS08545
uniprot id: F5Z0X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

875328:JDM601 RS11230
gene id: 875328:JDM601_RS11230
uniprot id: F5YU39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS05850
gene id: 875328:JDM601_RS05850
uniprot id: F5YVA8
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

875328:JDM601 RS13650
gene id: 875328:JDM601_RS13650
uniprot id: F5YYG1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

875328:JDM601 RS04615
gene id: 875328:JDM601_RS04615
uniprot id: F5YT87
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS12565
gene id: 875328:JDM601_RS12565
uniprot id: F5YW86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS07420
gene id: 875328:JDM601_RS07420
uniprot id: F5YY88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

875328:JDM601 RS20270
gene id: 875328:JDM601_RS20270
uniprot id: F5YTM7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

875328:JDM601 RS07330
gene id: 875328:JDM601_RS07330
uniprot id: F5YY68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

875328:JDM601 RS12715
gene id: 875328:JDM601_RS12715
uniprot id: F5YWS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

875328:JDM601 RS02070
gene id: 875328:JDM601_RS02070
uniprot id: F5Z0M6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS16295
gene id: 875328:JDM601_RS16295
uniprot id: F5YXP7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS04310
gene id: 875328:JDM601_RS04310
uniprot id: F5YSL8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

875328:JDM601 RS11235
gene id: 875328:JDM601_RS11235
uniprot id: F5YU40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

875328:JDM601 RS14395
gene id: 875328:JDM601_RS14395
uniprot id: F5Z087
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

875328:JDM601 RS16535
gene id: 875328:JDM601_RS16535
uniprot id: F5YXU6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

875328:JDM601 RS01180
gene id: 875328:JDM601_RS01180
uniprot id: F5YYS3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

875328:JDM601 RS24100
gene id: 875328:JDM601_RS24100
uniprot id: F5YVG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

875328:JDM601 RS24255
gene id: 875328:JDM601_RS24255
uniprot id: F5Z167
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS08790
gene id: 875328:JDM601_RS08790
uniprot id: F5Z1R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

875328:JDM601 RS07785
gene id: 875328:JDM601_RS07785
uniprot id: F5YZ47
names: Similarity
messages: Belongs to the thioesterase family.

875328:JDM601 RS14815
gene id: 875328:JDM601_RS14815
uniprot id: F5Z158
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

875328:JDM601 RS17150
gene id: 875328:JDM601_RS17150
uniprot id: F5YZJ6
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS11930
gene id: 875328:JDM601_RS11930
uniprot id: F5YVF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

875328:JDM601 RS03160
gene id: 875328:JDM601_RS03160
uniprot id: F5Z3B2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS15825
gene id: 875328:JDM601_RS15825
uniprot id: F5Z3S7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

875328:JDM601 RS05590
gene id: 875328:JDM601_RS05590
uniprot id: F5YV54
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS08530
gene id: 875328:JDM601_RS08530
uniprot id: F5Z0X2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

875328:JDM601 RS14995
gene id: 875328:JDM601_RS14995
uniprot id: F5Z195
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

875328:JDM601 RS12970
gene id: 875328:JDM601_RS12970
uniprot id: F5YWX4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS21580
gene id: 875328:JDM601_RS21580
uniprot id: F5YVR9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

875328:JDM601 RS16620
gene id: 875328:JDM601_RS16620
uniprot id: F5YYJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

875328:JDM601 RS06100
gene id: 875328:JDM601_RS06100
uniprot id: F5YVW5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

875328:JDM601 RS01795
gene id: 875328:JDM601_RS01795
uniprot id: F5YZT4
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS01050
gene id: 875328:JDM601_RS01050
uniprot id: F5YY10
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

875328:JDM601 RS20790
gene id: 875328:JDM601_RS20790
uniprot id: F5YUE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

875328:JDM601 RS11340
gene id: 875328:JDM601_RS11340
uniprot id: F5YU61
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

875328:JDM601 RS17170
gene id: 875328:JDM601_RS17170
uniprot id: F5YZK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS16275
gene id: 875328:JDM601_RS16275
uniprot id: F5YXP2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS05825
gene id: 875328:JDM601_RS05825
uniprot id: F5YVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

875328:JDM601 RS06495
gene id: 875328:JDM601_RS06495
uniprot id: F5YWK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

875328:JDM601 RS20455
gene id: 875328:JDM601_RS20455
uniprot id: F5YTR5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

875328:JDM601 RS20500
gene id: 875328:JDM601_RS20500
uniprot id: F5YU82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS08200
gene id: 875328:JDM601_RS08200
uniprot id: F5Z016
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

875328:JDM601 RS00235
gene id: 875328:JDM601_RS00235
uniprot id: F5YWE7
names: Similarity
messages: Belongs to the EccE family.

875328:JDM601 RS09240
gene id: 875328:JDM601_RS09240
uniprot id: F5Z2P0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

875328:JDM601 RS11530
gene id: 875328:JDM601_RS11530
uniprot id: F5YUR1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

875328:JDM601 RS01730
gene id: 875328:JDM601_RS01730
uniprot id: F5YZS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

875328:JDM601 RS13835
gene id: 875328:JDM601_RS13835
uniprot id: F5YZ87
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

875328:JDM601 RS07610
gene id: 875328:JDM601_RS07610
uniprot id: F5YZ12
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

875328:JDM601 RS09815
gene id: 875328:JDM601_RS09815
uniprot id: F5Z3P3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

875328:JDM601 RS13740
gene id: 875328:JDM601_RS13740
uniprot id: F5YYH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS11870
gene id: 875328:JDM601_RS11870
uniprot id: F5YVE0
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS10840
gene id: 875328:JDM601_RS10840
uniprot id: F5YTF5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

875328:JDM601 RS16610
gene id: 875328:JDM601_RS16610
uniprot id: F5YYJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

875328:JDM601 RS21545
gene id: 875328:JDM601_RS21545
uniprot id: F5YVR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS19180
gene id: 875328:JDM601_RS19180
uniprot id: F5YRQ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS01330
gene id: 875328:JDM601_RS01330
uniprot id: F5YYV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

875328:JDM601 RS14040
gene id: 875328:JDM601_RS14040
uniprot id: F5YZD0
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS00030
gene id: 875328:JDM601_RS00030
uniprot id: F5YWA5
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

875328:JDM601 RS08850
gene id: 875328:JDM601_RS08850
uniprot id: F5Z1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

875328:JDM601 RS12760
gene id: 875328:JDM601_RS12760
uniprot id: F5YWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

875328:JDM601 RS05050
gene id: 875328:JDM601_RS05050
uniprot id: F5YTX7
names: Similarity
messages: Belongs to the WXG100 family.

875328:JDM601 RS02095
gene id: 875328:JDM601_RS02095
uniprot id: F5Z0N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

875328:JDM601 RS00870
gene id: 875328:JDM601_RS00870
uniprot id: F5YXX5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

875328:JDM601 RS15610
gene id: 875328:JDM601_RS15610
uniprot id: F5Z2Z4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

875328:JDM601 RS11450
gene id: 875328:JDM601_RS11450
uniprot id: F5YUP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

875328:JDM601 RS21640
gene id: 875328:JDM601_RS21640
uniprot id: F5YVT1
names: Similarity
messages: Belongs to the thioredoxin family.

875328:JDM601 RS16875
gene id: 875328:JDM601_RS16875
uniprot id: F5YYQ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS14315
gene id: 875328:JDM601_RS14315
uniprot id: F5Z071
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

875328:JDM601 RS08610
gene id: 875328:JDM601_RS08610
uniprot id: F5Z0Y9
names: Similarity
messages: Belongs to the MmpS family.

875328:JDM601 RS06080
gene id: 875328:JDM601_RS06080
uniprot id: F5YVW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

875328:JDM601 RS13470
gene id: 875328:JDM601_RS13470
uniprot id: F5YYC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

875328:JDM601 RS07410
gene id: 875328:JDM601_RS07410
uniprot id: F5YY85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

875328:JDM601 RS14065
gene id: 875328:JDM601_RS14065
uniprot id: F5YZD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

875328:JDM601 RS18860
gene id: 875328:JDM601_RS18860
uniprot id: A0A1A2EBL2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

875328:JDM601 RS21675
gene id: 875328:JDM601_RS21675
uniprot id: F5YW97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

875328:JDM601 RS18735
gene id: 875328:JDM601_RS18735
uniprot id: F5Z368
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS02810
gene id: 875328:JDM601_RS02810
uniprot id: F5Z2F5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

875328:JDM601 RS01975
gene id: 875328:JDM601_RS01975
uniprot id: F5Z0K7
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS07205
gene id: 875328:JDM601_RS07205
uniprot id: F5YY45
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

875328:JDM601 RS01325
gene id: 875328:JDM601_RS01325
uniprot id: F5YYV1
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

875328:JDM601 RS17650
gene id: 875328:JDM601_RS17650
uniprot id: F5Z0I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

875328:JDM601 RS05615
gene id: 875328:JDM601_RS05615
uniprot id: F5YV59
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS08965
gene id: 875328:JDM601_RS08965
uniprot id: F5Z1U6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

875328:JDM601 RS11190
gene id: 875328:JDM601_RS11190
uniprot id: F5YU31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

875328:JDM601 RS02105
gene id: 875328:JDM601_RS02105
uniprot id: F5Z0N3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

875328:JDM601 RS09695
gene id: 875328:JDM601_RS09695
uniprot id: F5Z3L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

875328:JDM601 RS09270
gene id: 875328:JDM601_RS09270
uniprot id: F5Z2P6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

875328:JDM601 RS11265
gene id: 875328:JDM601_RS11265
uniprot id: F5YU46
names: Similarity
messages: Belongs to the peptidase C40 family.

875328:JDM601 RS01160
gene id: 875328:JDM601_RS01160
uniprot id: F5YY34
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

875328:JDM601 RS02210
gene id: 875328:JDM601_RS02210
uniprot id: F5Z0Q5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS13305
gene id: 875328:JDM601_RS13305
uniprot id: F5YXK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

875328:JDM601 RS03980
gene id: 875328:JDM601_RS03980
uniprot id: F5YSF3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

875328:JDM601 RS19885
gene id: 875328:JDM601_RS19885
uniprot id: F5YSZ4
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

875328:JDM601 RS00475
gene id: 875328:JDM601_RS00475
uniprot id: F5YX08
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS05840
gene id: 875328:JDM601_RS05840
uniprot id: F5YVA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

875328:JDM601 RS17760
gene id: 875328:JDM601_RS17760
uniprot id: F5Z196
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS05450
gene id: 875328:JDM601_RS05450
uniprot id: F5YUL6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

875328:JDM601 RS16215
gene id: 875328:JDM601_RS16215
uniprot id: F5YXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

875328:JDM601 RS20735
gene id: 875328:JDM601_RS20735
uniprot id: F5YUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

875328:JDM601 RS07115
gene id: 875328:JDM601_RS07115
uniprot id: F5YXD6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS03665
gene id: 875328:JDM601_RS03665
uniprot id: F5YRV7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS18455
gene id: 875328:JDM601_RS18455
uniprot id: F5Z2C4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS11910
gene id: 875328:JDM601_RS11910
uniprot id: F5YVE8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

875328:JDM601 RS02455
gene id: 875328:JDM601_RS02455
uniprot id: F5Z1J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

875328:JDM601 RS17845
gene id: 875328:JDM601_RS17845
uniprot id: F5Z1B3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

875328:JDM601 RS19930
gene id: 875328:JDM601_RS19930
uniprot id: F5YT02
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

875328:JDM601 RS17770
gene id: 875328:JDM601_RS17770
uniprot id: F5Z198
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

875328:JDM601 RS17060
gene id: 875328:JDM601_RS17060
uniprot id: F5YZH7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS01450
gene id: 875328:JDM601_RS01450
uniprot id: F5YYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

875328:JDM601 RS10750
gene id: 875328:JDM601_RS10750
uniprot id: F5YTD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

875328:JDM601 RS13685
gene id: 875328:JDM601_RS13685
uniprot id: F5YYG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

875328:JDM601 RS13125
gene id: 875328:JDM601_RS13125
uniprot id: F5YXH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

875328:JDM601 RS13150
gene id: 875328:JDM601_RS13150
uniprot id: F5YXH5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

875328:JDM601 RS09215
gene id: 875328:JDM601_RS09215
uniprot id: F5Z2N5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

875328:JDM601 RS01360
gene id: 875328:JDM601_RS01360
uniprot id: F5YYV7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

875328:JDM601 RS03455
gene id: 875328:JDM601_RS03455
uniprot id: F5Z3H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

875328:JDM601 RS11995
gene id: 875328:JDM601_RS11995
uniprot id: F5YVG6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

875328:JDM601 RS17420
gene id: 875328:JDM601_RS17420
uniprot id: F5Z0D8
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS16655
gene id: 875328:JDM601_RS16655
uniprot id: F5YYK6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

875328:JDM601 RS09615
gene id: 875328:JDM601_RS09615
uniprot id: F5Z3K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

875328:JDM601 RS12765
gene id: 875328:JDM601_RS12765
uniprot id: F5YWT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

875328:JDM601 RS04530
gene id: 875328:JDM601_RS04530
uniprot id: F5YT70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

875328:JDM601 RS11205
gene id: 875328:JDM601_RS11205
uniprot id: F5YU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

875328:JDM601 RS11490
gene id: 875328:JDM601_RS11490
uniprot id: F5YUQ3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

875328:JDM601 RS18780
gene id: 875328:JDM601_RS18780
uniprot id: F5Z377
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS04100
gene id: 875328:JDM601_RS04100
uniprot id: F5YSH7
names: Similarity
messages: Belongs to the citrate synthase family.

875328:JDM601 RS19300
gene id: 875328:JDM601_RS19300
uniprot id: F5YRS4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS19905
gene id: 875328:JDM601_RS19905
uniprot id: F5YSZ8
names: Similarity
messages: Belongs to the catalase family.

875328:JDM601 RS16760
gene id: 875328:JDM601_RS16760
uniprot id: F5YYM8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

875328:JDM601 RS01700
gene id: 875328:JDM601_RS01700
uniprot id: F5YZR4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

875328:JDM601 RS07555
gene id: 875328:JDM601_RS07555
uniprot id: F5YYB4
names: Similarity
messages: Belongs to the MmpS family.

875328:JDM601 RS08205
gene id: 875328:JDM601_RS08205
uniprot id: F5Z017
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS16095
gene id: 875328:JDM601_RS16095
uniprot id: F5Z3Y2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS17850
gene id: 875328:JDM601_RS17850
uniprot id: F5Z1B4
names: Similarity
messages: Belongs to the peptidase M18 family.

875328:JDM601 RS17400
gene id: 875328:JDM601_RS17400
uniprot id: F5Z0D3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS04745
gene id: 875328:JDM601_RS04745
uniprot id: F5YTB4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

875328:JDM601 RS08420
gene id: 875328:JDM601_RS08420
uniprot id: F5Z0U9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

875328:JDM601 RS01445
gene id: 875328:JDM601_RS01445
uniprot id: F5YYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

875328:JDM601 RS07685
gene id: 875328:JDM601_RS07685
uniprot id: F5YZ27
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

875328:JDM601 RS18020
gene id: 875328:JDM601_RS18020
uniprot id: F5Z1E8
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS09065
gene id: 875328:JDM601_RS09065
uniprot id: F5Z1W6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

875328:JDM601 RS09265
gene id: 875328:JDM601_RS09265
uniprot id: F5Z2P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

875328:JDM601 RS07875
gene id: 875328:JDM601_RS07875
uniprot id: F5YZ65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell envelope
messages: Exhibits GTPase activity. Binds RNA but is probably not involved in ribosome assembly in mycobacteria.
messages: Monomer.
messages: cell wall

875328:JDM601 RS17410
gene id: 875328:JDM601_RS17410
uniprot id: F5Z0D6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS13130
gene id: 875328:JDM601_RS13130
uniprot id: F5YXH1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

875328:JDM601 RS09930
gene id: 875328:JDM601_RS09930
uniprot id: F5YS07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

875328:JDM601 RS20900
gene id: 875328:JDM601_RS20900
uniprot id: F5YUX8
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS01775
gene id: 875328:JDM601_RS01775
uniprot id: F5YZT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS09075
gene id: 875328:JDM601_RS09075
uniprot id: F5Z1W8
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

875328:JDM601 RS20665
gene id: 875328:JDM601_RS20665
uniprot id: F5YUB7
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS16735
gene id: 875328:JDM601_RS16735
uniprot id: F5YYM2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

875328:JDM601 RS02265
gene id: 875328:JDM601_RS02265
uniprot id: F5Z0R6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

875328:JDM601 RS14785
gene id: 875328:JDM601_RS14785
uniprot id: F5Z152
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

875328:JDM601 RS11295
gene id: 875328:JDM601_RS11295
uniprot id: F5YU52
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS05730
gene id: 875328:JDM601_RS05730
uniprot id: F5YV84
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

875328:JDM601 RS02055
gene id: 875328:JDM601_RS02055
uniprot id: F5Z0M3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS19275
gene id: 875328:JDM601_RS19275
uniprot id: F5YRR9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

875328:JDM601 RS10545
gene id: 875328:JDM601_RS10545
uniprot id: F5YST9
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS11975
gene id: 875328:JDM601_RS11975
uniprot id: F5YVG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

875328:JDM601 RS05225
gene id: 875328:JDM601_RS05225
uniprot id: F5YUH0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS08795
gene id: 875328:JDM601_RS08795
uniprot id: F5Z1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS18845
gene id: 875328:JDM601_RS18845
uniprot id: F5Z390
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

875328:JDM601 RS01255
gene id: 875328:JDM601_RS01255
uniprot id: F5YYT8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS01680
gene id: 875328:JDM601_RS01680
uniprot id: F5YZR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

875328:JDM601 RS17635
gene id: 875328:JDM601_RS17635
uniprot id: F5Z0I1
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

875328:JDM601 RS11390
gene id: 875328:JDM601_RS11390
uniprot id: F5YU71
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS12625
gene id: 875328:JDM601_RS12625
uniprot id: F5YWQ4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

875328:JDM601 RS07465
gene id: 875328:JDM601_RS07465
uniprot id: F5YY97
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

875328:JDM601 RS01715
gene id: 875328:JDM601_RS01715
uniprot id: F5YZR7
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

875328:JDM601 RS07680
gene id: 875328:JDM601_RS07680
uniprot id: F5YZ26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

875328:JDM601 RS13200
gene id: 875328:JDM601_RS13200
uniprot id: F5YXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

875328:JDM601 RS04295
gene id: 875328:JDM601_RS04295
uniprot id: F5YSL5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS17755
gene id: 875328:JDM601_RS17755
uniprot id: F5Z0K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

875328:JDM601 RS00470
gene id: 875328:JDM601_RS00470
uniprot id: F5YX07
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

875328:JDM601 RS14025
gene id: 875328:JDM601_RS14025
uniprot id: F5YZC7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS14800
gene id: 875328:JDM601_RS14800
uniprot id: F5Z155
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS17870
gene id: 875328:JDM601_RS17870
uniprot id: F5Z1B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

875328:JDM601 RS11005
gene id: 875328:JDM601_RS11005
uniprot id: F5YTJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

875328:JDM601 RS04115
gene id: 875328:JDM601_RS04115
uniprot id: F5YSI0
names: Similarity
messages: Belongs to the citrate synthase family.

875328:JDM601 RS03265
gene id: 875328:JDM601_RS03265
uniprot id: F5Z3D1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

875328:JDM601 RS19325
gene id: 875328:JDM601_RS19325
uniprot id: F5YRS9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

875328:JDM601 RS08880
gene id: 875328:JDM601_RS08880
uniprot id: F5Z1T0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

875328:JDM601 RS01690
gene id: 875328:JDM601_RS01690
uniprot id: F5YZR2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

875328:JDM601 RS04230
gene id: 875328:JDM601_RS04230
uniprot id: F5YSK3
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS12425
gene id: 875328:JDM601_RS12425
uniprot id: F5YW58
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

875328:JDM601 RS09340
gene id: 875328:JDM601_RS09340
uniprot id: F5Z2R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS07135
gene id: 875328:JDM601_RS07135
uniprot id: F5YXE0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

875328:JDM601 RS20680
gene id: 875328:JDM601_RS20680
uniprot id: F5YUC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

875328:JDM601 RS16740
gene id: 875328:JDM601_RS16740
uniprot id: F5YYM4
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS07650
gene id: 875328:JDM601_RS07650
uniprot id: F5YZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

875328:JDM601 RS12380
gene id: 875328:JDM601_RS12380
uniprot id: F5YW49
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

875328:JDM601 RS02040
gene id: 875328:JDM601_RS02040
uniprot id: F5Z0M0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS05020
gene id: 875328:JDM601_RS05020
uniprot id: F5YTX1
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS00965
gene id: 875328:JDM601_RS00965
uniprot id: F5YXZ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS19680
gene id: 875328:JDM601_RS19680
uniprot id: F5YSE3
names: Similarity
messages: Belongs to the GSP E family.

875328:JDM601 RS04385
gene id: 875328:JDM601_RS04385
uniprot id: F5YT41
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

875328:JDM601 RS11410
gene id: 875328:JDM601_RS11410
uniprot id: F5YU77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

875328:JDM601 RS06655
gene id: 875328:JDM601_RS06655
uniprot id: F5YWN2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

875328:JDM601 RS12675
gene id: 875328:JDM601_RS12675
uniprot id: F5YWR4
names: Similarity
messages: Belongs to the AccD/PCCB family.

875328:JDM601 RS00075
gene id: 875328:JDM601_RS00075
uniprot id: F5YWB2
names: Similarity
messages: Belongs to the UPF0749 family.

875328:JDM601 RS04965
gene id: 875328:JDM601_RS04965
uniprot id: F5YTW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

875328:JDM601 RS19445
gene id: 875328:JDM601_RS19445
uniprot id: F5YS98
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

875328:JDM601 RS19295
gene id: 875328:JDM601_RS19295
uniprot id: F5YRS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

875328:JDM601 RS14925
gene id: 875328:JDM601_RS14925
uniprot id: F5Z181
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

875328:JDM601 RS00070
gene id: 875328:JDM601_RS00070
uniprot id: F5YWB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

875328:JDM601 RS07190
gene id: 875328:JDM601_RS07190
uniprot id: F5YY42
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS14960
gene id: 875328:JDM601_RS14960
uniprot id: F5Z188
names: Similarity
messages: Belongs to the band 7/mec-2 family.

875328:JDM601 RS14015
gene id: 875328:JDM601_RS14015
uniprot id: F5YZC5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

875328:JDM601 RS19260
gene id: 875328:JDM601_RS19260
uniprot id: F5YRR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

875328:JDM601 RS07170
gene id: 875328:JDM601_RS07170
uniprot id: F5YY38
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

875328:JDM601 RS06575
gene id: 875328:JDM601_RS06575
uniprot id: F5YWM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

875328:JDM601 RS18180
gene id: 875328:JDM601_RS18180
uniprot id: F5Z269
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS18165
gene id: 875328:JDM601_RS18165
uniprot id: F5Z266
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS15750
gene id: 875328:JDM601_RS15750
uniprot id: F5Z325
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS09315
gene id: 875328:JDM601_RS09315
uniprot id: F5Z2Q5
names: Similarity
messages: Belongs to the UPF0434 family.

875328:JDM601 RS16600
gene id: 875328:JDM601_RS16600
uniprot id: F5YYJ5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

875328:JDM601 RS14035
gene id: 875328:JDM601_RS14035
uniprot id: F5YZC9
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS15095
gene id: 875328:JDM601_RS15095
uniprot id: F5Z203
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS11955
gene id: 875328:JDM601_RS11955
uniprot id: F5YVF7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

875328:JDM601 RS20950
gene id: 875328:JDM601_RS20950
uniprot id: F5YUY8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS12275
gene id: 875328:JDM601_RS12275
uniprot id: F5YW28
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

875328:JDM601 RS08490
gene id: 875328:JDM601_RS08490
uniprot id: F5Z0W4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

875328:JDM601 RS19500
gene id: 875328:JDM601_RS19500
uniprot id: F5YSA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

875328:JDM601 RS01485
gene id: 875328:JDM601_RS01485
uniprot id: F5YYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

875328:JDM601 RS04015
gene id: 875328:JDM601_RS04015
uniprot id: F5YSG0
names: Similarity
messages: Belongs to the MoaD family.

875328:JDM601 RS13515
gene id: 875328:JDM601_RS13515
uniprot id: F5YYD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial histone-like protein family. Long actinobacterial subfamily.
messages: nucleoid

875328:JDM601 RS01765
gene id: 875328:JDM601_RS01765
uniprot id: F5YZS8
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS15960
gene id: 875328:JDM601_RS15960
uniprot id: F5Z3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

875328:JDM601 RS14920
gene id: 875328:JDM601_RS14920
uniprot id: F5Z180
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

875328:JDM601 RS06335
gene id: 875328:JDM601_RS06335
uniprot id: F5YW13
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

875328:JDM601 RS20510
gene id: 875328:JDM601_RS20510
uniprot id: F5YU84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS14010
gene id: 875328:JDM601_RS14010
uniprot id: F5YZC4
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

875328:JDM601 RS07965
gene id: 875328:JDM601_RS07965
uniprot id: F5YZX1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

875328:JDM601 RS20385
gene id: 875328:JDM601_RS20385
uniprot id: F5YTQ0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

875328:JDM601 RS17685
gene id: 875328:JDM601_RS17685
uniprot id: F5Z0J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

875328:JDM601 RS16390
gene id: 875328:JDM601_RS16390
uniprot id: F5YXR6
names: Similarity
messages: Belongs to the WXG100 family.

875328:JDM601 RS19840
gene id: 875328:JDM601_RS19840
uniprot id: F5YSY5
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS20250
gene id: 875328:JDM601_RS20250
uniprot id: F5YTM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

875328:JDM601 RS04030
gene id: 875328:JDM601_RS04030
uniprot id: F5YSG3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS19585
gene id: 875328:JDM601_RS19585
uniprot id: F5YSC8
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS06195
gene id: 875328:JDM601_RS06195
uniprot id: F5YVY4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

875328:JDM601 RS12415
gene id: 875328:JDM601_RS12415
uniprot id: F5YW56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

875328:JDM601 RS11135
gene id: 875328:JDM601_RS11135
uniprot id: F5YU19
names: Similarity
messages: Belongs to the acyltransferase PapA5 family.

875328:JDM601 RS08355
gene id: 875328:JDM601_RS08355
uniprot id: F5Z047
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

875328:JDM601 RS12195
gene id: 875328:JDM601_RS12195
uniprot id: F5YVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

875328:JDM601 RS07575
gene id: 875328:JDM601_RS07575
uniprot id: F5YZ05
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS12585
gene id: 875328:JDM601_RS12585
uniprot id: F5YW90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS07290
gene id: 875328:JDM601_RS07290
uniprot id: F5YY62
names: Similarity
messages: Belongs to the peptidase M1 family.

875328:JDM601 RS10985
gene id: 875328:JDM601_RS10985
uniprot id: F5YTI5
names: Subcellular Location Annotation
messages: Cytoplasm

875328:JDM601 RS20810
gene id: 875328:JDM601_RS20810
uniprot id: F5YUE8
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

875328:JDM601 RS08405
gene id: 875328:JDM601_RS08405
uniprot id: F5Z0U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

875328:JDM601 RS12480
gene id: 875328:JDM601_RS12480
uniprot id: F5YW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS17570
gene id: 875328:JDM601_RS17570
uniprot id: F5Z0G8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

875328:JDM601 RS07345
gene id: 875328:JDM601_RS07345
uniprot id: A0A1A2EBF5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

875328:JDM601 RS04945
gene id: 875328:JDM601_RS04945
uniprot id: F5YTV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

875328:JDM601 RS20015
gene id: 875328:JDM601_RS20015
uniprot id: F5YT20
names: Similarity
messages: Belongs to the CFA/CMAS family.

875328:JDM601 RS01780
gene id: 875328:JDM601_RS01780
uniprot id: F5YZT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

875328:JDM601 RS03630
gene id: 875328:JDM601_RS03630
uniprot id: F5YRV0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS02340
gene id: 875328:JDM601_RS02340
uniprot id: F5Z0T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

875328:JDM601 RS08050
gene id: 875328:JDM601_RS08050
uniprot id: F5YZY8
names: Similarity
messages: Belongs to the peptidase U62 family.

875328:JDM601 RS15990
gene id: 875328:JDM601_RS15990
uniprot id: F5Z3W1
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family.
messages: Homotetramer.

875328:JDM601 RS10215
gene id: 875328:JDM601_RS10215
uniprot id: F5YS65
names: Similarity
messages: Belongs to the CFA/CMAS family.

875328:JDM601 RS17210
gene id: 875328:JDM601_RS17210
uniprot id: F5YZK8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

875328:JDM601 RS06600
gene id: 875328:JDM601_RS06600
uniprot id: F5YWM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS13665
gene id: 875328:JDM601_RS13665
uniprot id: F5YYG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS13295
gene id: 875328:JDM601_RS13295
uniprot id: F5YXK5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

875328:JDM601 RS19160
gene id: 875328:JDM601_RS19160
uniprot id: F5YRP7
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS05115
gene id: 875328:JDM601_RS05115
uniprot id: F5YTY9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS16070
gene id: 875328:JDM601_RS16070
uniprot id: F5Z3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

875328:JDM601 RS18590
gene id: 875328:JDM601_RS18590
uniprot id: F5Z338
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS13725
gene id: 875328:JDM601_RS13725
uniprot id: F5YYH6
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

875328:JDM601 RS01140
gene id: 875328:JDM601_RS01140
uniprot id: F5YY30
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

875328:JDM601 RS10920
gene id: 875328:JDM601_RS10920
uniprot id: F5YTH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

875328:JDM601 RS08765
gene id: 875328:JDM601_RS08765
uniprot id: F5Z1Q8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

875328:JDM601 RS06460
gene id: 875328:JDM601_RS06460
uniprot id: F5YWJ9
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS06705
gene id: 875328:JDM601_RS06705
uniprot id: F5YWP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

875328:JDM601 RS21280
gene id: 875328:JDM601_RS21280
uniprot id: F5YVK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS12325
gene id: 875328:JDM601_RS12325
uniprot id: F5YW38
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS00840
gene id: 875328:JDM601_RS00840
uniprot id: F5YXW9
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS19510
gene id: 875328:JDM601_RS19510
uniprot id: F5YSB1
names: Similarity
messages: Belongs to the peptidase S13 family.

875328:JDM601 RS15785
gene id: 875328:JDM601_RS15785
uniprot id: F5Z3R9
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS11460
gene id: 875328:JDM601_RS11460
uniprot id: F5YUP7
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS18240
gene id: 875328:JDM601_RS18240
uniprot id: F5Z282
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

875328:JDM601 RS05120
gene id: 875328:JDM601_RS05120
uniprot id: F5YTZ0
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

875328:JDM601 RS12035
gene id: 875328:JDM601_RS12035
uniprot id: F5YVH4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

875328:JDM601 RS07830
gene id: 875328:JDM601_RS07830
uniprot id: F5YZ56
names: Similarity
messages: Belongs to the group II decarboxylase family.

875328:JDM601 RS03335
gene id: 875328:JDM601_RS03335
uniprot id: F5Z3E5
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

875328:JDM601 RS05990
gene id: 875328:JDM601_RS05990
uniprot id: F5YVU3
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS10825
gene id: 875328:JDM601_RS10825
uniprot id: F5YTF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

875328:JDM601 RS15245
gene id: 875328:JDM601_RS15245
uniprot id: F5Z234
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

875328:JDM601 RS09655
gene id: 875328:JDM601_RS09655
uniprot id: F5Z3K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

875328:JDM601 RS06675
gene id: 875328:JDM601_RS06675
uniprot id: F5YWN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

875328:JDM601 RS11350
gene id: 875328:JDM601_RS11350
uniprot id: F5YU63
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

875328:JDM601 RS12995
gene id: 875328:JDM601_RS12995
uniprot id: F5YWX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

875328:JDM601 RS04890
gene id: 875328:JDM601_RS04890
uniprot id: F5YTU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

875328:JDM601 RS06560
gene id: 875328:JDM601_RS06560
uniprot id: F5YWL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

875328:JDM601 RS16690
gene id: 875328:JDM601_RS16690
uniprot id: F5YYL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

875328:JDM601 RS16085
gene id: 875328:JDM601_RS16085
uniprot id: F5Z3Y0
names: Similarity
messages: Belongs to the universal stress protein A family.

875328:JDM601 RS16715
gene id: 875328:JDM601_RS16715
uniprot id: F5YYL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

875328:JDM601 RS04975
gene id: 875328:JDM601_RS04975
uniprot id: F5YTW2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS10500
gene id: 875328:JDM601_RS10500
uniprot id: F5YST0
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

875328:JDM601 RS14895
gene id: 875328:JDM601_RS14895
uniprot id: F5Z175
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

875328:JDM601 RS15230
gene id: 875328:JDM601_RS15230
uniprot id: F5Z231
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS24260
gene id: 875328:JDM601_RS24260
uniprot id: F5Z173
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS19530
gene id: 875328:JDM601_RS19530
uniprot id: F5YSB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

875328:JDM601 RS20795
gene id: 875328:JDM601_RS20795
uniprot id: F5YUE4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

875328:JDM601 RS06585
gene id: 875328:JDM601_RS06585
uniprot id: F5YWM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

875328:JDM601 RS11435
gene id: 875328:JDM601_RS11435
uniprot id: F5YUP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

875328:JDM601 RS01800
gene id: 875328:JDM601_RS01800
uniprot id: F5YZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS01880
gene id: 875328:JDM601_RS01880
uniprot id: F5YZV1
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

875328:JDM601 RS00140
gene id: 875328:JDM601_RS00140
uniprot id: F5YWC5
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

875328:JDM601 RS02255
gene id: 875328:JDM601_RS02255
uniprot id: F5Z0R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

875328:JDM601 RS09210
gene id: 875328:JDM601_RS09210
uniprot id: F5Z2N4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

875328:JDM601 RS18205
gene id: 875328:JDM601_RS18205
uniprot id: F5Z275
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS14710
gene id: 875328:JDM601_RS14710
uniprot id: F5Z138
names: Similarity
messages: Belongs to the DEAD box helicase family.

875328:JDM601 RS24215
gene id: 875328:JDM601_RS24215
uniprot id: F5Z1L5
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS13975
gene id: 875328:JDM601_RS13975
uniprot id: F5YZB7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

875328:JDM601 RS17895
gene id: 875328:JDM601_RS17895
uniprot id: F5Z1C3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

875328:JDM601 RS20145
gene id: 875328:JDM601_RS20145
uniprot id: F5YTK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

875328:JDM601 RS04380
gene id: 875328:JDM601_RS04380
uniprot id: F5YT40
names: Similarity
messages: Belongs to the UPF0166 family.

875328:JDM601 RS13845
gene id: 875328:JDM601_RS13845
uniprot id: F5YZ89
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS01135
gene id: 875328:JDM601_RS01135
uniprot id: F5YY29
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS07605
gene id: 875328:JDM601_RS07605
uniprot id: F5YZ11
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

875328:JDM601 RS09600
gene id: 875328:JDM601_RS09600
uniprot id: F5Z3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccD/Snm4 family.
messages: Membrane

875328:JDM601 RS08830
gene id: 875328:JDM601_RS08830
uniprot id: F5Z1S1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

875328:JDM601 RS08900
gene id: 875328:JDM601_RS08900
uniprot id: F5Z1T3
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS03955
gene id: 875328:JDM601_RS03955
uniprot id: F5YS02
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS09740
gene id: 875328:JDM601_RS09740
uniprot id: F5Z3M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

875328:JDM601 RS10585
gene id: 875328:JDM601_RS10585
uniprot id: F5YSU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS15295
gene id: 875328:JDM601_RS15295
uniprot id: F5Z244
names: Similarity
messages: Belongs to the SufE family.

875328:JDM601 RS19720
gene id: 875328:JDM601_RS19720
uniprot id: F5YSF1
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS17425
gene id: 875328:JDM601_RS17425
uniprot id: F5Z0D9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS11370
gene id: 875328:JDM601_RS11370
uniprot id: F5YU67
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS11075
gene id: 875328:JDM601_RS11075
uniprot id: F5YU08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS07700
gene id: 875328:JDM601_RS07700
uniprot id: F5YZ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

875328:JDM601 RS17605
gene id: 875328:JDM601_RS17605
uniprot id: F5Z0H5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS10930
gene id: 875328:JDM601_RS10930
uniprot id: F5YTH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

875328:JDM601 RS24055
gene id: 875328:JDM601_RS24055
uniprot id: F5YT56
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

875328:JDM601 RS16955
gene id: 875328:JDM601_RS16955
uniprot id: F5YYR9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS13930
gene id: 875328:JDM601_RS13930
uniprot id: F5YZA6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

875328:JDM601 RS14405
gene id: 875328:JDM601_RS14405
uniprot id: F5Z089
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

875328:JDM601 RS08525
gene id: 875328:JDM601_RS08525
uniprot id: F5Z0X1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

875328:JDM601 RS09260
gene id: 875328:JDM601_RS09260
uniprot id: F5Z2P4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

875328:JDM601 RS02370
gene id: 875328:JDM601_RS02370
uniprot id: F5Z1H6
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

875328:JDM601 RS19575
gene id: 875328:JDM601_RS19575
uniprot id: F5YSC6
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS06700
gene id: 875328:JDM601_RS06700
uniprot id: F5YWP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

875328:JDM601 RS07480
gene id: 875328:JDM601_RS07480
uniprot id: F5YY99
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

875328:JDM601 RS10170
gene id: 875328:JDM601_RS10170
uniprot id: F5YS56
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

875328:JDM601 RS08925
gene id: 875328:JDM601_RS08925
uniprot id: F5Z1T8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

875328:JDM601 RS02730
gene id: 875328:JDM601_RS02730
uniprot id: F5Z1Q1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

875328:JDM601 RS08910
gene id: 875328:JDM601_RS08910
uniprot id: F5Z1T5
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS08800
gene id: 875328:JDM601_RS08800
uniprot id: F5Z1R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

875328:JDM601 RS06865
gene id: 875328:JDM601_RS06865
uniprot id: F5YX92
names: Similarity
messages: Belongs to the HsdR family.

875328:JDM601 RS06685
gene id: 875328:JDM601_RS06685
uniprot id: F5YWN8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

875328:JDM601 RS19015
gene id: 875328:JDM601_RS19015
uniprot id: F5YRL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS23295
gene id: 875328:JDM601_RS23295
uniprot id: F5YWD9
names: Similarity
messages: Belongs to the peptidase C40 family.

875328:JDM601 RS04720
gene id: 875328:JDM601_RS04720
uniprot id: F5YTA9
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS08970
gene id: 875328:JDM601_RS08970
uniprot id: F5Z1U7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS03685
gene id: 875328:JDM601_RS03685
uniprot id: F5YRW1
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS11030
gene id: 875328:JDM601_RS11030
uniprot id: F5YTJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

875328:JDM601 RS00020
gene id: 875328:JDM601_RS00020
uniprot id: F5YWA3
names: Similarity
messages: Belongs to the UPF0232 family.

875328:JDM601 RS16385
gene id: 875328:JDM601_RS16385
uniprot id: F5YXR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

875328:JDM601 RS04830
gene id: 875328:JDM601_RS04830
uniprot id: F5YTT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

875328:JDM601 RS15710
gene id: 875328:JDM601_RS15710
uniprot id: F5Z316
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

875328:JDM601 RS07100
gene id: 875328:JDM601_RS07100
uniprot id: F5YXD3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

875328:JDM601 RS15870
gene id: 875328:JDM601_RS15870
uniprot id: F5Z3T6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

875328:JDM601 RS19065
gene id: 875328:JDM601_RS19065
uniprot id: F5YRM5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS16055
gene id: 875328:JDM601_RS16055
uniprot id: F5Z3X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS03565
gene id: 875328:JDM601_RS03565
uniprot id: F5YRT6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS01845
gene id: 875328:JDM601_RS01845
uniprot id: F5YZU4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS06555
gene id: 875328:JDM601_RS06555
uniprot id: F5YWL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

875328:JDM601 RS16570
gene id: 875328:JDM601_RS16570
uniprot id: F5YXV3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS12920
gene id: 875328:JDM601_RS12920
uniprot id: F5YWW4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS02090
gene id: 875328:JDM601_RS02090
uniprot id: F5Z0N0
names: Function
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate.

875328:JDM601 RS11020
gene id: 875328:JDM601_RS11020
uniprot id: F5YTJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

875328:JDM601 RS15980
gene id: 875328:JDM601_RS15980
uniprot id: F5Z3V8
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS10035
gene id: 875328:JDM601_RS10035
uniprot id: F5YS28
names: Similarity
messages: Belongs to the CinA family.

875328:JDM601 RS09830
gene id: 875328:JDM601_RS09830
uniprot id: F5Z3P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

875328:JDM601 RS10765
gene id: 875328:JDM601_RS10765
uniprot id: F5YTE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

875328:JDM601 RS02675
gene id: 875328:JDM601_RS02675
uniprot id: F5Z1P0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS04630
gene id: 875328:JDM601_RS04630
uniprot id: F5YT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS19340
gene id: 875328:JDM601_RS19340
uniprot id: F5YS75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS23155
gene id: 875328:JDM601_RS23155
uniprot id: F5Z214
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

875328:JDM601 RS09220
gene id: 875328:JDM601_RS09220
uniprot id: F5Z2N6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

875328:JDM601 RS04120
gene id: 875328:JDM601_RS04120
uniprot id: F5YSI1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

875328:JDM601 RS12745
gene id: 875328:JDM601_RS12745
uniprot id: F5YWS7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS06075
gene id: 875328:JDM601_RS06075
uniprot id: F5YVW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

875328:JDM601 RS07130
gene id: 875328:JDM601_RS07130
uniprot id: F5YXD9
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

875328:JDM601 RS20005
gene id: 875328:JDM601_RS20005
uniprot id: F5YT18
names: Similarity
messages: Belongs to the CFA/CMAS family.

875328:JDM601 RS00900
gene id: 875328:JDM601_RS00900
uniprot id: F5YXY1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS13250
gene id: 875328:JDM601_RS13250
uniprot id: F5YXJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

875328:JDM601 RS07260
gene id: 875328:JDM601_RS07260
uniprot id: F5YY56
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

875328:JDM601 RS20505
gene id: 875328:JDM601_RS20505
uniprot id: F5YU83
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS01915
gene id: 875328:JDM601_RS01915
uniprot id: F5YZV8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

875328:JDM601 RS04525
gene id: 875328:JDM601_RS04525
uniprot id: F5YT69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

875328:JDM601 RS14935
gene id: 875328:JDM601_RS14935
uniprot id: F5Z183
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

875328:JDM601 RS05285
gene id: 875328:JDM601_RS05285
uniprot id: F5YUI2
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

875328:JDM601 RS13510
gene id: 875328:JDM601_RS13510
uniprot id: F5YYD5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

875328:JDM601 RS19935
gene id: 875328:JDM601_RS19935
uniprot id: F5YT04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS04405
gene id: 875328:JDM601_RS04405
uniprot id: F5YT45
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

875328:JDM601 RS07770
gene id: 875328:JDM601_RS07770
uniprot id: F5YZ44
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS08245
gene id: 875328:JDM601_RS08245
uniprot id: F5Z025
names: Similarity
messages: Belongs to the TPP enzyme family.

875328:JDM601 RS17110
gene id: 875328:JDM601_RS17110
uniprot id: F5YZI7
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

875328:JDM601 RS09060
gene id: 875328:JDM601_RS09060
uniprot id: F5Z1W5
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

875328:JDM601 RS12060
gene id: 875328:JDM601_RS12060
uniprot id: F5YVH9
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS11760
gene id: 875328:JDM601_RS11760
uniprot id: F5YUV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

875328:JDM601 RS00725
gene id: 875328:JDM601_RS00725
uniprot id: F5YX59
names: Similarity
messages: Belongs to the pirin family.

875328:JDM601 RS19290
gene id: 875328:JDM601_RS19290
uniprot id: F5YRS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

875328:JDM601 RS04685
gene id: 875328:JDM601_RS04685
uniprot id: F5YTA1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS19410
gene id: 875328:JDM601_RS19410
uniprot id: F5YS91
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS19040
gene id: 875328:JDM601_RS19040
uniprot id: F5YRM0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS13220
gene id: 875328:JDM601_RS13220
uniprot id: F5YXI9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

875328:JDM601 RS10200
gene id: 875328:JDM601_RS10200
uniprot id: F5YS62
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

875328:JDM601 RS13215
gene id: 875328:JDM601_RS13215
uniprot id: F5YXI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

875328:JDM601 RS11770
gene id: 875328:JDM601_RS11770
uniprot id: F5YUW0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

875328:JDM601 RS15495
gene id: 875328:JDM601_RS15495
uniprot id: F5Z2W9
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

875328:JDM601 RS05670
gene id: 875328:JDM601_RS05670
uniprot id: F5YV70
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS02075
gene id: 875328:JDM601_RS02075
uniprot id: F5Z0M7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS01075
gene id: 875328:JDM601_RS01075
uniprot id: F5YY15
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.

875328:JDM601 RS06415
gene id: 875328:JDM601_RS06415
uniprot id: F5YWJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS14940
gene id: 875328:JDM601_RS14940
uniprot id: F5Z184
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

875328:JDM601 RS00770
gene id: 875328:JDM601_RS00770
uniprot id: F5YX68
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

875328:JDM601 RS16710
gene id: 875328:JDM601_RS16710
uniprot id: F5YYL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

875328:JDM601 RS06715
gene id: 875328:JDM601_RS06715
uniprot id: F5YWP4
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS11750
gene id: 875328:JDM601_RS11750
uniprot id: F5YUV6
names: Similarity
messages: Belongs to the peptidase A24 family.

875328:JDM601 RS06550
gene id: 875328:JDM601_RS06550
uniprot id: F5YWL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

875328:JDM601 RS00015
gene id: 875328:JDM601_RS00015
uniprot id: F5YWA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

875328:JDM601 RS11900
gene id: 875328:JDM601_RS11900
uniprot id: F5YVE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS09640
gene id: 875328:JDM601_RS09640
uniprot id: F5Z3K6
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS02010
gene id: 875328:JDM601_RS02010
uniprot id: F5Z0L4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

875328:JDM601 RS09595
gene id: 875328:JDM601_RS09595
uniprot id: F5Z3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

875328:JDM601 RS14745
gene id: 875328:JDM601_RS14745
uniprot id: F5Z144
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

875328:JDM601 RS16230
gene id: 875328:JDM601_RS16230
uniprot id: F5YXN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

875328:JDM601 RS00285
gene id: 875328:JDM601_RS00285
uniprot id: F5YWF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

875328:JDM601 RS09765
gene id: 875328:JDM601_RS09765
uniprot id: F5Z3N1
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS20120
gene id: 875328:JDM601_RS20120
uniprot id: F5YTJ8
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

875328:JDM601 RS20920
gene id: 875328:JDM601_RS20920
uniprot id: F5YUY2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS01920
gene id: 875328:JDM601_RS01920
uniprot id: F5YZV9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS01695
gene id: 875328:JDM601_RS01695
uniprot id: F5YZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

875328:JDM601 RS12930
gene id: 875328:JDM601_RS12930
uniprot id: F5YWW6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

875328:JDM601 RS07930
gene id: 875328:JDM601_RS07930
uniprot id: F5YZ76
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

875328:JDM601 RS06430
gene id: 875328:JDM601_RS06430
uniprot id: F5YWJ3
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

875328:JDM601 RS06185
gene id: 875328:JDM601_RS06185
uniprot id: F5YVY2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

875328:JDM601 RS19900
gene id: 875328:JDM601_RS19900
uniprot id: F5YSZ7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

875328:JDM601 RS11935
gene id: 875328:JDM601_RS11935
uniprot id: F5YVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

875328:JDM601 RS21625
gene id: 875328:JDM601_RS21625
uniprot id: F5YVS8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

875328:JDM601 RS11645
gene id: 875328:JDM601_RS11645
uniprot id: F5YUT5
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

875328:JDM601 RS21020
gene id: 875328:JDM601_RS21020
uniprot id: F5YV01
names: Similarity
messages: Belongs to the MmpS family.

875328:JDM601 RS19945
gene id: 875328:JDM601_RS19945
uniprot id: F5YT06
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

875328:JDM601 RS07455
gene id: 875328:JDM601_RS07455
uniprot id: F5YY95
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

875328:JDM601 RS11525
gene id: 875328:JDM601_RS11525
uniprot id: F5YUR0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

875328:JDM601 RS17460
gene id: 875328:JDM601_RS17460
uniprot id: F5Z0E6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

875328:JDM601 RS09100
gene id: 875328:JDM601_RS09100
uniprot id: F5Z1X3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

875328:JDM601 RS00740
gene id: 875328:JDM601_RS00740
uniprot id: F5YX62
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

875328:JDM601 RS01810
gene id: 875328:JDM601_RS01810
uniprot id: F5YZT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

875328:JDM601 RS10530
gene id: 875328:JDM601_RS10530
uniprot id: F5YST6
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS21655
gene id: 875328:JDM601_RS21655
uniprot id: F5YVT4
names: Similarity
messages: Belongs to the ParB family.

875328:JDM601 RS12100
gene id: 875328:JDM601_RS12100
uniprot id: F5YVI7
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS19890
gene id: 875328:JDM601_RS19890
uniprot id: F5YSZ5
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

875328:JDM601 RS16680
gene id: 875328:JDM601_RS16680
uniprot id: F5YYL1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

875328:JDM601 RS09935
gene id: 875328:JDM601_RS09935
uniprot id: F5YS08
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS13355
gene id: 875328:JDM601_RS13355
uniprot id: F5YXL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

875328:JDM601 RS11575
gene id: 875328:JDM601_RS11575
uniprot id: F5YUS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

875328:JDM601 RS08595
gene id: 875328:JDM601_RS08595
uniprot id: F5Z0Y6
names: Similarity
messages: Belongs to the asparagine synthetase family.

875328:JDM601 RS12670
gene id: 875328:JDM601_RS12670
uniprot id: F5YWR3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

875328:JDM601 RS13465
gene id: 875328:JDM601_RS13465
uniprot id: F5YYC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

875328:JDM601 RS03305
gene id: 875328:JDM601_RS03305
uniprot id: F5Z3D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

875328:JDM601 RS10795
gene id: 875328:JDM601_RS10795
uniprot id: F5YTE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

875328:JDM601 RS19280
gene id: 875328:JDM601_RS19280
uniprot id: F5YRS0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

875328:JDM601 RS03715
gene id: 875328:JDM601_RS03715
uniprot id: F5YRW7
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

875328:JDM601 RS14610
gene id: 875328:JDM601_RS14610
uniprot id: F5Z118
names: Similarity
messages: Belongs to the peptidase S16 family.

875328:JDM601 RS16530
gene id: 875328:JDM601_RS16530
uniprot id: F5YXU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

875328:JDM601 RS13455
gene id: 875328:JDM601_RS13455
uniprot id: F5YYC4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

875328:JDM601 RS05025
gene id: 875328:JDM601_RS05025
uniprot id: F5YTX2
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS09865
gene id: 875328:JDM601_RS09865
uniprot id: F5Z3Q3
names: Similarity
messages: Belongs to the XFP family.

875328:JDM601 RS12190
gene id: 875328:JDM601_RS12190
uniprot id: F5YVK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

875328:JDM601 RS14155
gene id: 875328:JDM601_RS14155
uniprot id: F5YZF3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS02775
gene id: 875328:JDM601_RS02775
uniprot id: F5Z2E9
names: Similarity
messages: Belongs to the UPF0234 family.

875328:JDM601 RS06035
gene id: 875328:JDM601_RS06035
uniprot id: F5YVV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

875328:JDM601 RS15100
gene id: 875328:JDM601_RS15100
uniprot id: F5Z204
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

875328:JDM601 RS16440
gene id: 875328:JDM601_RS16440
uniprot id: F5YXS5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

875328:JDM601 RS16235
gene id: 875328:JDM601_RS16235
uniprot id: A0A1A3TM49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

875328:JDM601 RS13410
gene id: 875328:JDM601_RS13410
uniprot id: F5YYB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

875328:JDM601 RS21530
gene id: 875328:JDM601_RS21530
uniprot id: F5YVQ8
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

875328:JDM601 RS02805
gene id: 875328:JDM601_RS02805
uniprot id: F5Z2F4
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

875328:JDM601 RS11480
gene id: 875328:JDM601_RS11480
uniprot id: F5YUQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

875328:JDM601 RS03295
gene id: 875328:JDM601_RS03295
uniprot id: F5Z3D6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

875328:JDM601 RS10860
gene id: 875328:JDM601_RS10860
uniprot id: F5YTF9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

875328:JDM601 RS19875
gene id: 875328:JDM601_RS19875
uniprot id: F5YSZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

875328:JDM601 RS10220
gene id: 875328:JDM601_RS10220
uniprot id: F5YS66
names: Similarity
messages: Belongs to the CFA/CMAS family.

875328:JDM601 RS07905
gene id: 875328:JDM601_RS07905
uniprot id: F5YZ71
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

875328:JDM601 RS15165
gene id: 875328:JDM601_RS15165
uniprot id: F5Z217
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

875328:JDM601 RS19330
gene id: 875328:JDM601_RS19330
uniprot id: F5YS73
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

875328:JDM601 RS11615
gene id: 875328:JDM601_RS11615
uniprot id: F5YUS9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

875328:JDM601 RS18000
gene id: 875328:JDM601_RS18000
uniprot id: F5Z1E4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS16430
gene id: 875328:JDM601_RS16430
uniprot id: F5YXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

875328:JDM601 RS21485
gene id: 875328:JDM601_RS21485
uniprot id: F5YVP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

875328:JDM601 RS10810
gene id: 875328:JDM601_RS10810
uniprot id: F5YTE9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

875328:JDM601 RS24195
gene id: 875328:JDM601_RS24195
uniprot id: F5YUC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

875328:JDM601 RS05510
gene id: 875328:JDM601_RS05510
uniprot id: F5YUM8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS09625
gene id: 875328:JDM601_RS09625
uniprot id: F5YTX7
names: Similarity
messages: Belongs to the WXG100 family.

875328:JDM601 RS10850
gene id: 875328:JDM601_RS10850
uniprot id: F5YTF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

875328:JDM601 RS16700
gene id: 875328:JDM601_RS16700
uniprot id: F5YYL5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

875328:JDM601 RS06465
gene id: 875328:JDM601_RS06465
uniprot id: F5YWK0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS04070
gene id: 875328:JDM601_RS04070
uniprot id: F5YSH1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

875328:JDM601 RS12945
gene id: 875328:JDM601_RS12945
uniprot id: F5YWW9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS07570
gene id: 875328:JDM601_RS07570
uniprot id: F5YZ04
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

875328:JDM601 RS14880
gene id: 875328:JDM601_RS14880
uniprot id: F5Z172
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS17540
gene id: 875328:JDM601_RS17540
uniprot id: F5Z0G2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS03995
gene id: 875328:JDM601_RS03995
uniprot id: F5YSF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

875328:JDM601 RS08080
gene id: 875328:JDM601_RS08080
uniprot id: F5YZZ3
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS10565
gene id: 875328:JDM601_RS10565
uniprot id: F5YSU3
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS02935
gene id: 875328:JDM601_RS02935
uniprot id: F5Z2I0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

875328:JDM601 RS10185
gene id: 875328:JDM601_RS10185
uniprot id: F5YS59
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

875328:JDM601 RS08440
gene id: 875328:JDM601_RS08440
uniprot id: F5Z0V3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

875328:JDM601 RS19570
gene id: 875328:JDM601_RS19570
uniprot id: F5YSC5
names: Similarity
messages: Belongs to the peptidase M1 family.

875328:JDM601 RS10735
gene id: 875328:JDM601_RS10735
uniprot id: F5YTD4
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS03200
gene id: 875328:JDM601_RS03200
uniprot id: F5Z3C0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS07695
gene id: 875328:JDM601_RS07695
uniprot id: F5YZ29
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

875328:JDM601 RS05395
gene id: 875328:JDM601_RS05395
uniprot id: F5YUK4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

875328:JDM601 RS19550
gene id: 875328:JDM601_RS19550
uniprot id: F5YSC1
names: Subcellular Location Annotation
messages: Cell membrane

875328:JDM601 RS16475
gene id: 875328:JDM601_RS16475
uniprot id: F5YXT3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

875328:JDM601 RS16545
gene id: 875328:JDM601_RS16545
uniprot id: F5YXU8
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

875328:JDM601 RS03745
gene id: 875328:JDM601_RS03745
uniprot id: F5YRX1
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

875328:JDM601 RS24225
gene id: 875328:JDM601_RS24225
uniprot id: F5YT83
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS04915
gene id: 875328:JDM601_RS04915
uniprot id: F5YTV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

875328:JDM601 RS11515
gene id: 875328:JDM601_RS11515
uniprot id: F5YUQ8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

875328:JDM601 RS15215
gene id: 875328:JDM601_RS15215
uniprot id: F5Z228
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

875328:JDM601 RS09905
gene id: 875328:JDM601_RS09905
uniprot id: F5Z3R2
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

875328:JDM601 RS06790
gene id: 875328:JDM601_RS06790
uniprot id: F5YX77
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

875328:JDM601 RS01065
gene id: 875328:JDM601_RS01065
uniprot id: F5YY13
names: Similarity
messages: Belongs to the WrbA family.

875328:JDM601 RS07005
gene id: 875328:JDM601_RS07005
uniprot id: F5YXB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

875328:JDM601 RS09275
gene id: 875328:JDM601_RS09275
uniprot id: F5Z2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

875328:JDM601 RS10730
gene id: 875328:JDM601_RS10730
uniprot id: F5YTD3
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

875328:JDM601 RS16685
gene id: 875328:JDM601_RS16685
uniprot id: F5YYL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

875328:JDM601 RS09650
gene id: 875328:JDM601_RS09650
uniprot id: F5Z3K8
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS18450
gene id: 875328:JDM601_RS18450
uniprot id: F5Z2C3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS00530
gene id: 875328:JDM601_RS00530
uniprot id: F5YX20
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

875328:JDM601 RS07580
gene id: 875328:JDM601_RS07580
uniprot id: F5YZ06
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS07415
gene id: 875328:JDM601_RS07415
uniprot id: F5YY86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

875328:JDM601 RS13370
gene id: 875328:JDM601_RS13370
uniprot id: F5YXM0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

875328:JDM601 RS16615
gene id: 875328:JDM601_RS16615
uniprot id: F5YYJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

875328:JDM601 RS09435
gene id: 875328:JDM601_RS09435
uniprot id: F5Z2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

875328:JDM601 RS10910
gene id: 875328:JDM601_RS10910
uniprot id: F5YTG9
names: Similarity
messages: Belongs to the peptidase C40 family.

875328:JDM601 RS13160
gene id: 875328:JDM601_RS13160
uniprot id: F5YXH7
names: Similarity
messages: Belongs to the DprA/Smf family.

875328:JDM601 RS11405
gene id: 875328:JDM601_RS11405
uniprot id: F5YU76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

875328:JDM601 RS08325
gene id: 875328:JDM601_RS08325
uniprot id: F5Z041
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS09795
gene id: 875328:JDM601_RS09795
uniprot id: F5Z3N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

875328:JDM601 RS08815
gene id: 875328:JDM601_RS08815
uniprot id: F5Z1R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

875328:JDM601 RS11960
gene id: 875328:JDM601_RS11960
uniprot id: F5YVF8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

875328:JDM601 RS11310
gene id: 875328:JDM601_RS11310
uniprot id: F5YU55
names: Subcellular Location Annotation
messages: Cell membrane

875328:JDM601 RS04920
gene id: 875328:JDM601_RS04920
uniprot id: F5YTV2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS18585
gene id: 875328:JDM601_RS18585
uniprot id: F5Z337
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS03270
gene id: 875328:JDM601_RS03270
uniprot id: F5Z3D2
names: Similarity
messages: Belongs to the UPF0336 family.

875328:JDM601 RS13580
gene id: 875328:JDM601_RS13580
uniprot id: F5YYE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

875328:JDM601 RS13105
gene id: 875328:JDM601_RS13105
uniprot id: F5YXG6
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS14325
gene id: 875328:JDM601_RS14325
uniprot id: F5Z073
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS05945
gene id: 875328:JDM601_RS05945
uniprot id: F5YVC7
names: Similarity
messages: Belongs to the LOG family.

875328:JDM601 RS03635
gene id: 875328:JDM601_RS03635
uniprot id: F5YRV1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS07495
gene id: 875328:JDM601_RS07495
uniprot id: F5YYA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

875328:JDM601 RS19490
gene id: 875328:JDM601_RS19490
uniprot id: F5Z2K2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

875328:JDM601 RS20285
gene id: 875328:JDM601_RS20285
uniprot id: F5YTN0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

875328:JDM601 RS10395
gene id: 875328:JDM601_RS10395
uniprot id: F5YSQ8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

875328:JDM601 RS07940
gene id: 875328:JDM601_RS07940
uniprot id: F5YZ78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS02755
gene id: 875328:JDM601_RS02755
uniprot id: F5Z2E5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS01380
gene id: 875328:JDM601_RS01380
uniprot id: F5YYW1
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

875328:JDM601 RS07835
gene id: 875328:JDM601_RS07835
uniprot id: F5YZ57
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

875328:JDM601 RS00270
gene id: 875328:JDM601_RS00270
uniprot id: F5YWF4
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS16540
gene id: 875328:JDM601_RS16540
uniprot id: F5YXU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

875328:JDM601 RS07660
gene id: 875328:JDM601_RS07660
uniprot id: F5YZ22
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

875328:JDM601 RS05460
gene id: 875328:JDM601_RS05460
uniprot id: F5YUL8
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

875328:JDM601 RS13015
gene id: 875328:JDM601_RS13015
uniprot id: F5YXE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

875328:JDM601 RS16375
gene id: 875328:JDM601_RS16375
uniprot id: F5YXR3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

875328:JDM601 RS17560
gene id: 875328:JDM601_RS17560
uniprot id: F5Z0G6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS09430
gene id: 875328:JDM601_RS09430
uniprot id: F5Z2S6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

875328:JDM601 RS04175
gene id: 875328:JDM601_RS04175
uniprot id: F5YSJ2
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS18470
gene id: 875328:JDM601_RS18470
uniprot id: F5Z2C7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS07720
gene id: 875328:JDM601_RS07720
uniprot id: F5YZ34
names: Similarity
messages: Belongs to the CsoR family.

875328:JDM601 RS22335
gene id: 875328:JDM601_RS22335
uniprot id: F5YXT0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

875328:JDM601 RS18500
gene id: 875328:JDM601_RS18500
uniprot id: F5Z2D5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS02630
gene id: 875328:JDM601_RS02630
uniprot id: F5Z1N1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS01080
gene id: 875328:JDM601_RS01080
uniprot id: F5YY16
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS20475
gene id: 875328:JDM601_RS20475
uniprot id: F5YTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS12595
gene id: 875328:JDM601_RS12595
uniprot id: F5YW92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

875328:JDM601 RS11725
gene id: 875328:JDM601_RS11725
uniprot id: F5YUV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

875328:JDM601 RS08555
gene id: 875328:JDM601_RS08555
uniprot id: F5Z0X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

875328:JDM601 RS16195
gene id: 875328:JDM601_RS16195
uniprot id: F5YWZ0
names: Similarity
messages: Belongs to the HIBADH-related family.

875328:JDM601 RS09370
gene id: 875328:JDM601_RS09370
uniprot id: F5Z2R3
names: Similarity
messages: Belongs to the TlyA family.

875328:JDM601 RS20340
gene id: 875328:JDM601_RS20340
uniprot id: F5YTP0
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

875328:JDM601 RS14860
gene id: 875328:JDM601_RS14860
uniprot id: F5Z168
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

875328:JDM601 RS04665
gene id: 875328:JDM601_RS04665
uniprot id: F5YT97
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

875328:JDM601 RS13575
gene id: 875328:JDM601_RS13575
uniprot id: F5YYE6
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

875328:JDM601 RS00005
gene id: 875328:JDM601_RS00005
uniprot id: F5YWA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

875328:JDM601 RS09915
gene id: 875328:JDM601_RS09915
uniprot id: F5Z3R4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

875328:JDM601 RS16355
gene id: 875328:JDM601_RS16355
uniprot id: F5YXQ9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

875328:JDM601 RS14355
gene id: 875328:JDM601_RS14355
uniprot id: F5Z079
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS02910
gene id: 875328:JDM601_RS02910
uniprot id: F5Z2H6
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS16455
gene id: 875328:JDM601_RS16455
uniprot id: F5YXS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

875328:JDM601 RS14055
gene id: 875328:JDM601_RS14055
uniprot id: F5YZD3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS05585
gene id: 875328:JDM601_RS05585
uniprot id: F5YV53
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS16270
gene id: 875328:JDM601_RS16270
uniprot id: F5YXP1
names: Similarity
messages: Belongs to the group II decarboxylase family.

875328:JDM601 RS15725
gene id: 875328:JDM601_RS15725
uniprot id: F5Z319
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

875328:JDM601 RS04290
gene id: 875328:JDM601_RS04290
uniprot id: F5YSL4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

875328:JDM601 RS01820
gene id: 875328:JDM601_RS01820
uniprot id: F5YZT9
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS09115
gene id: 875328:JDM601_RS09115
uniprot id: F5Z1X6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

875328:JDM601 RS08085
gene id: 875328:JDM601_RS08085
uniprot id: F5YZZ4
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS17700
gene id: 875328:JDM601_RS17700
uniprot id: F5Z0J5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

875328:JDM601 RS19960
gene id: 875328:JDM601_RS19960
uniprot id: F5YT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

875328:JDM601 RS18405
gene id: 875328:JDM601_RS18405
uniprot id: F5Z2B3
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

875328:JDM601 RS16380
gene id: 875328:JDM601_RS16380
uniprot id: F5YXR4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

875328:JDM601 RS02835
gene id: 875328:JDM601_RS02835
uniprot id: F5Z2G0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS19515
gene id: 875328:JDM601_RS19515
uniprot id: F5YSB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

875328:JDM601 RS09375
gene id: 875328:JDM601_RS09375
uniprot id: F5Z2R4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS19370
gene id: 875328:JDM601_RS19370
uniprot id: F5YS82
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

875328:JDM601 RS02275
gene id: 875328:JDM601_RS02275
uniprot id: F5Z0R9
names: Cofactor
messages: Can also use Mn(2+) ion.

875328:JDM601 RS07080
gene id: 875328:JDM601_RS07080
uniprot id: F5YXC9
names: Similarity
messages: Belongs to the MmpS family.

875328:JDM601 RS01895
gene id: 875328:JDM601_RS01895
uniprot id: F5YZV4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS09135
gene id: 875328:JDM601_RS09135
uniprot id: F5Z1Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

875328:JDM601 RS03365
gene id: 875328:JDM601_RS03365
uniprot id: F5Z3F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

875328:JDM601 RS15885
gene id: 875328:JDM601_RS15885
uniprot id: F5Z3T9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

875328:JDM601 RS15015
gene id: 875328:JDM601_RS15015
uniprot id: F5Z1Y7
names: Similarity
messages: Belongs to the thymidylate kinase family.

875328:JDM601 RS06410
gene id: 875328:JDM601_RS06410
uniprot id: F5YWI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS16705
gene id: 875328:JDM601_RS16705
uniprot id: F5YYL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

875328:JDM601 RS14820
gene id: 875328:JDM601_RS14820
uniprot id: F5Z159
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

875328:JDM601 RS21265
gene id: 875328:JDM601_RS21265
uniprot id: F5YV50
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS10140
gene id: 875328:JDM601_RS10140
uniprot id: F5YS50
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS00785
gene id: 875328:JDM601_RS00785
uniprot id: F5YXV8
names: Similarity
messages: Belongs to the CsoR family.

875328:JDM601 RS20230
gene id: 875328:JDM601_RS20230
uniprot id: F5YTL9
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

875328:JDM601 RS06595
gene id: 875328:JDM601_RS06595
uniprot id: F5YWM5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

875328:JDM601 RS06765
gene id: 875328:JDM601_RS06765
uniprot id: F5YX72
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

875328:JDM601 RS10740
gene id: 875328:JDM601_RS10740
uniprot id: F5YTD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

875328:JDM601 RS17935
gene id: 875328:JDM601_RS17935
uniprot id: F5Z1D1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

875328:JDM601 RS13565
gene id: 875328:JDM601_RS13565
uniprot id: F5YYE4
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

875328:JDM601 RS12405
gene id: 875328:JDM601_RS12405
uniprot id: F5YW54
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS05140
gene id: 875328:JDM601_RS05140
uniprot id: F5YTZ3
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS15940
gene id: 875328:JDM601_RS15940
uniprot id: F5Z3V0
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS11675
gene id: 875328:JDM601_RS11675
uniprot id: F5YUU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

875328:JDM601 RS08060
gene id: 875328:JDM601_RS08060
uniprot id: F5YZZ0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

875328:JDM601 RS00865
gene id: 875328:JDM601_RS00865
uniprot id: F5YXX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

875328:JDM601 RS00410
gene id: 875328:JDM601_RS00410
uniprot id: F5YWZ5
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS04460
gene id: 875328:JDM601_RS04460
uniprot id: F5YT55
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

875328:JDM601 RS21475
gene id: 875328:JDM601_RS21475
uniprot id: F5YVP7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

875328:JDM601 RS10230
gene id: 875328:JDM601_RS10230
uniprot id: F5YS68
names: Similarity
messages: Belongs to the CFA/CMAS family.

875328:JDM601 RS17670
gene id: 875328:JDM601_RS17670
uniprot id: F5Z0I8
names: Subcellular Location Annotation
messages: Cell membrane

875328:JDM601 RS12570
gene id: 875328:JDM601_RS12570
uniprot id: F5YW87
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

875328:JDM601 RS09775
gene id: 875328:JDM601_RS09775
uniprot id: F5Z3N3
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

875328:JDM601 RS09010
gene id: 875328:JDM601_RS09010
uniprot id: F5Z1V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

875328:JDM601 RS20020
gene id: 875328:JDM601_RS20020
uniprot id: F5YT21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

875328:JDM601 RS07840
gene id: 875328:JDM601_RS07840
uniprot id: F5YZ58
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

875328:JDM601 RS17580
gene id: 875328:JDM601_RS17580
uniprot id: F5Z0H0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS07865
gene id: 875328:JDM601_RS07865
uniprot id: F5YZ63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

875328:JDM601 RS02315
gene id: 875328:JDM601_RS02315
uniprot id: F5Z0S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

875328:JDM601 RS17610
gene id: 875328:JDM601_RS17610
uniprot id: F5Z0H6
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

875328:JDM601 RS07760
gene id: 875328:JDM601_RS07760
uniprot id: F5YZ42
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

875328:JDM601 RS09090
gene id: 875328:JDM601_RS09090
uniprot id: F5Z1X1
names: Similarity
messages: Belongs to the UPF0235 family.

875328:JDM601 RS16465
gene id: 875328:JDM601_RS16465
uniprot id: F5YXT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

875328:JDM601 RS19780
gene id: 875328:JDM601_RS19780
uniprot id: F5YSX4
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

875328:JDM601 RS12110
gene id: 875328:JDM601_RS12110
uniprot id: F5YVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS11640
gene id: 875328:JDM601_RS11640
uniprot id: F5YUT4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

875328:JDM601 RS02135
gene id: 875328:JDM601_RS02135
uniprot id: F5Z0N9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS09380
gene id: 875328:JDM601_RS09380
uniprot id: F5Z2R5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

875328:JDM601 RS08715
gene id: 875328:JDM601_RS08715
uniprot id: F5Z109
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

875328:JDM601 RS06710
gene id: 875328:JDM601_RS06710
uniprot id: F5YWP3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

875328:JDM601 RS19450
gene id: 875328:JDM601_RS19450
uniprot id: F5YS99
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

875328:JDM601 RS14370
gene id: 875328:JDM601_RS14370
uniprot id: F5Z082
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

875328:JDM601 RS07530
gene id: 875328:JDM601_RS07530
uniprot id: F5YYA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

875328:JDM601 RS16550
gene id: 875328:JDM601_RS16550
uniprot id: F5YXU9
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

875328:JDM601 RS11810
gene id: 875328:JDM601_RS11810
uniprot id: F5YUW8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

875328:JDM601 RS16630
gene id: 875328:JDM601_RS16630
uniprot id: F5YYK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

875328:JDM601 RS09290
gene id: 875328:JDM601_RS09290
uniprot id: F5Z2Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

875328:JDM601 RS08445
gene id: 875328:JDM601_RS08445
uniprot id: F5Z0V4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

875328:JDM601 RS08560
gene id: 875328:JDM601_RS08560
uniprot id: F5Z0X8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

875328:JDM601 RS20395
gene id: 875328:JDM601_RS20395
uniprot id: F5YTQ2
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS03490
gene id: 875328:JDM601_RS03490
uniprot id: F5Z3H7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS09585
gene id: 875328:JDM601_RS09585
uniprot id: F5YTX7
names: Similarity
messages: Belongs to the WXG100 family.

875328:JDM601 RS08320
gene id: 875328:JDM601_RS08320
uniprot id: F5Z040
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

875328:JDM601 RS08040
gene id: 875328:JDM601_RS08040
uniprot id: F5YZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

875328:JDM601 RS07385
gene id: 875328:JDM601_RS07385
uniprot id: F5YY80
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

875328:JDM601 RS10820
gene id: 875328:JDM601_RS10820
uniprot id: F5YTF1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

875328:JDM601 RS05630
gene id: 875328:JDM601_RS05630
uniprot id: F5YV62
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS04695
gene id: 875328:JDM601_RS04695
uniprot id: F5YTA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

875328:JDM601 RS16725
gene id: 875328:JDM601_RS16725
uniprot id: F5YYM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

875328:JDM601 RS10285
gene id: 875328:JDM601_RS10285
uniprot id: F5YSN7
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

875328:JDM601 RS24155
gene id: 875328:JDM601_RS24155
uniprot id: F5Z1C6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

875328:JDM601 RS16080
gene id: 875328:JDM601_RS16080
uniprot id: F5Z3X9
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS06225
gene id: 875328:JDM601_RS06225
uniprot id: F5YVZ0
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS08110
gene id: 875328:JDM601_RS08110
uniprot id: F5YZZ9
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS19955
gene id: 875328:JDM601_RS19955
uniprot id: F5YT08
names: Similarity
messages: Belongs to the CdaR family.

875328:JDM601 RS07845
gene id: 875328:JDM601_RS07845
uniprot id: F5YZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

875328:JDM601 RS13755
gene id: 875328:JDM601_RS13755
uniprot id: F5YYI2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

875328:JDM601 RS19415
gene id: 875328:JDM601_RS19415
uniprot id: F5YS92
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

875328:JDM601 RS10515
gene id: 875328:JDM601_RS10515
uniprot id: F5YST3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

875328:JDM601 RS10700
gene id: 875328:JDM601_RS10700
uniprot id: F5YTC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

875328:JDM601 RS21150
gene id: 875328:JDM601_RS21150
uniprot id: F5YV27
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS05980
gene id: 875328:JDM601_RS05980
uniprot id: F5YVU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

875328:JDM601 RS10880
gene id: 875328:JDM601_RS10880
uniprot id: F5YTG3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

875328:JDM601 RS17940
gene id: 875328:JDM601_RS17940
uniprot id: F5Z1D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

875328:JDM601 RS11335
gene id: 875328:JDM601_RS11335
uniprot id: F5YU60
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

875328:JDM601 RS14375
gene id: 875328:JDM601_RS14375
uniprot id: F5Z083
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

875328:JDM601 RS07425
gene id: 875328:JDM601_RS07425
uniprot id: F5YY89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

875328:JDM601 RS18025
gene id: 875328:JDM601_RS18025
uniprot id: F5Z1E9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

875328:JDM601 RS03520
gene id: 875328:JDM601_RS03520
uniprot id: F5Z3I3
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS20405
gene id: 875328:JDM601_RS20405
uniprot id: F5YTQ4
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

875328:JDM601 RS16640
gene id: 875328:JDM601_RS16640
uniprot id: F5YYK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

875328:JDM601 RS16480
gene id: 875328:JDM601_RS16480
uniprot id: F5YXT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

875328:JDM601 RS11920
gene id: 875328:JDM601_RS11920
uniprot id: F5YVF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS10540
gene id: 875328:JDM601_RS10540
uniprot id: F5YST8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

875328:JDM601 RS10845
gene id: 875328:JDM601_RS10845
uniprot id: F5YTF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

875328:JDM601 RS09150
gene id: 875328:JDM601_RS09150
uniprot id: F5Z1Y3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

875328:JDM601 RS15270
gene id: 875328:JDM601_RS15270
uniprot id: F5Z239
names: Similarity
messages: Belongs to the AccD/PCCB family.

875328:JDM601 RS20760
gene id: 875328:JDM601_RS20760
uniprot id: F5YUD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

875328:JDM601 RS05635
gene id: 875328:JDM601_RS05635
uniprot id: F5YV63
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS06180
gene id: 875328:JDM601_RS06180
uniprot id: F5YVY1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

875328:JDM601 RS10725
gene id: 875328:JDM601_RS10725
uniprot id: F5YTD2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

875328:JDM601 RS10835
gene id: 875328:JDM601_RS10835
uniprot id: F5YTF4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

875328:JDM601 RS00950
gene id: 875328:JDM601_RS00950
uniprot id: F5YXZ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS19880
gene id: 875328:JDM601_RS19880
uniprot id: F5YSZ3
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

875328:JDM601 RS11635
gene id: 875328:JDM601_RS11635
uniprot id: F5YUT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

875328:JDM601 RS06570
gene id: 875328:JDM601_RS06570
uniprot id: F5YWM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

875328:JDM601 RS20545
gene id: 875328:JDM601_RS20545
uniprot id: F5YU93
names: Similarity
messages: Belongs to the AccD/PCCB family.

875328:JDM601 RS16670
gene id: 875328:JDM601_RS16670
uniprot id: F5YYK9
names: Similarity
messages: Belongs to the EccE family.

875328:JDM601 RS08505
gene id: 875328:JDM601_RS08505
uniprot id: F5Z0W7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

875328:JDM601 RS15640
gene id: 875328:JDM601_RS15640
uniprot id: F5Z301
names: Similarity
messages: Belongs to the FPG family.

875328:JDM601 RS12875
gene id: 875328:JDM601_RS12875
uniprot id: F5YWV5
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS05660
gene id: 875328:JDM601_RS05660
uniprot id: F5YV68
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

875328:JDM601 RS09805
gene id: 875328:JDM601_RS09805
uniprot id: F5Z3P1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

875328:JDM601 RS12655
gene id: 875328:JDM601_RS12655
uniprot id: F5YWR0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS07790
gene id: 875328:JDM601_RS07790
uniprot id: F5YZ48
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

875328:JDM601 RS08410
gene id: 875328:JDM601_RS08410
uniprot id: F5Z0U7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

875328:JDM601 RS18870
gene id: 875328:JDM601_RS18870
uniprot id: F5Z395
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS05220
gene id: 875328:JDM601_RS05220
uniprot id: F5YUG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

875328:JDM601 RS03510
gene id: 875328:JDM601_RS03510
uniprot id: F5Z3I1
names: Similarity
messages: Belongs to the AccD/PCCB family.

875328:JDM601 RS09700
gene id: 875328:JDM601_RS09700
uniprot id: F5Z3L8
names: Similarity
messages: Belongs to the UPF0749 family.

875328:JDM601 RS02610
gene id: 875328:JDM601_RS02610
uniprot id: F5Z1M6
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS10225
gene id: 875328:JDM601_RS10225
uniprot id: F5YS67
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

875328:JDM601 RS21015
gene id: 875328:JDM601_RS21015
uniprot id: F5YV00
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS01395
gene id: 875328:JDM601_RS01395
uniprot id: F5YYW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

875328:JDM601 RS08535
gene id: 875328:JDM601_RS08535
uniprot id: F5Z0X3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

875328:JDM601 RS22580
gene id: 875328:JDM601_RS22580
uniprot id: F5YW99
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

875328:JDM601 RS04510
gene id: 875328:JDM601_RS04510
uniprot id: F5YT66
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

875328:JDM601 RS16145
gene id: 875328:JDM601_RS16145
uniprot id: F5Z3Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

875328:JDM601 RS01365
gene id: 875328:JDM601_RS01365
uniprot id: F5YYV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

875328:JDM601 RS19115
gene id: 875328:JDM601_RS19115
uniprot id: F5YRN8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS21620
gene id: 875328:JDM601_RS21620
uniprot id: F5YVS7
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS10060
gene id: 875328:JDM601_RS10060
uniprot id: F5YS33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

875328:JDM601 RS13240
gene id: 875328:JDM601_RS13240
uniprot id: F5YXJ3
names: Similarity
messages: Belongs to the peptidase S11 family.

875328:JDM601 RS12235
gene id: 875328:JDM601_RS12235
uniprot id: F5YW20
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

875328:JDM601 RS16450
gene id: 875328:JDM601_RS16450
uniprot id: F5YXS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

875328:JDM601 RS03300
gene id: 875328:JDM601_RS03300
uniprot id: F5Z3D7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

875328:JDM601 RS20970
gene id: 875328:JDM601_RS20970
uniprot id: F5YUZ2
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS14275
gene id: 875328:JDM601_RS14275
uniprot id: F5Z063
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

875328:JDM601 RS02330
gene id: 875328:JDM601_RS02330
uniprot id: F5Z0T0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

875328:JDM601 RS12230
gene id: 875328:JDM601_RS12230
uniprot id: F5YW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS02765
gene id: 875328:JDM601_RS02765
uniprot id: F5Z2E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

875328:JDM601 RS17695
gene id: 875328:JDM601_RS17695
uniprot id: F5Z0J4
names: Similarity
messages: Belongs to the PstS family.

875328:JDM601 RS02820
gene id: 875328:JDM601_RS02820
uniprot id: F5Z2F7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

875328:JDM601 RS15880
gene id: 875328:JDM601_RS15880
uniprot id: F5Z3T8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

875328:JDM601 RS10875
gene id: 875328:JDM601_RS10875
uniprot id: F5YTG2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS04170
gene id: 875328:JDM601_RS04170
uniprot id: F5YSJ1
names: Similarity
messages: Belongs to the AccD/PCCB family.

875328:JDM601 RS14320
gene id: 875328:JDM601_RS14320
uniprot id: F5Z072
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS14805
gene id: 875328:JDM601_RS14805
uniprot id: F5Z156
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS18175
gene id: 875328:JDM601_RS18175
uniprot id: F5Z268
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS09500
gene id: 875328:JDM601_RS09500
uniprot id: F5Z2U1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

875328:JDM601 RS21560
gene id: 875328:JDM601_RS21560
uniprot id: F5YVR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS11855
gene id: 875328:JDM601_RS11855
uniprot id: F5YVD7
names: Similarity
messages: Belongs to the WXG100 family.

875328:JDM601 RS09250
gene id: 875328:JDM601_RS09250
uniprot id: F5Z2P2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

875328:JDM601 RS11170
gene id: 875328:JDM601_RS11170
uniprot id: F5YU27
names: Similarity
messages: Belongs to the thioesterase family.

875328:JDM601 RS11470
gene id: 875328:JDM601_RS11470
uniprot id: F5YUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

875328:JDM601 RS17765
gene id: 875328:JDM601_RS17765
uniprot id: F5Z197
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS07200
gene id: 875328:JDM601_RS07200
uniprot id: F5YY44
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

875328:JDM601 RS01945
gene id: 875328:JDM601_RS01945
uniprot id: F5YZW4
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

875328:JDM601 RS08115
gene id: 875328:JDM601_RS08115
uniprot id: F5Z000
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

875328:JDM601 RS12610
gene id: 875328:JDM601_RS12610
uniprot id: F5YW95
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

875328:JDM601 RS13765
gene id: 875328:JDM601_RS13765
uniprot id: F5YYI4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

875328:JDM601 RS06505
gene id: 875328:JDM601_RS06505
uniprot id: F5YWK7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

875328:JDM601 RS09165
gene id: 875328:JDM601_RS09165
uniprot id: F5Z2M5
names: Similarity
messages: Belongs to the universal stress protein A family.

875328:JDM601 RS04940
gene id: 875328:JDM601_RS04940
uniprot id: F5YTV6
names: Similarity
messages: Belongs to the ArsC family.

875328:JDM601 RS09180
gene id: 875328:JDM601_RS09180
uniprot id: F5Z2M8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

875328:JDM601 RS07920
gene id: 875328:JDM601_RS07920
uniprot id: F5YZ74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

875328:JDM601 RS03280
gene id: 875328:JDM601_RS03280
uniprot id: F5Z3D4
names: Similarity
messages: Belongs to the UPF0336 family.

875328:JDM601 RS12890
gene id: 875328:JDM601_RS12890
uniprot id: F5YWV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

875328:JDM601 RS00175
gene id: 875328:JDM601_RS00175
uniprot id: F5YWD2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

875328:JDM601 RS13955
gene id: 875328:JDM601_RS13955
uniprot id: F5YZB3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

875328:JDM601 RS05640
gene id: 875328:JDM601_RS05640
uniprot id: F5YV64
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS14345
gene id: 875328:JDM601_RS14345
uniprot id: F5Z077
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

875328:JDM601 RS12045
gene id: 875328:JDM601_RS12045
uniprot id: F5YVH6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS01970
gene id: 875328:JDM601_RS01970
uniprot id: F5YZW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

875328:JDM601 RS03470
gene id: 875328:JDM601_RS03470
uniprot id: F5Z3H3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS14640
gene id: 875328:JDM601_RS14640
uniprot id: F5Z124
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

875328:JDM601 RS05350
gene id: 875328:JDM601_RS05350
uniprot id: F5YUJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

875328:JDM601 RS13165
gene id: 875328:JDM601_RS13165
uniprot id: F5YXH8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

875328:JDM601 RS10040
gene id: 875328:JDM601_RS10040
uniprot id: F5YS29
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

875328:JDM601 RS01965
gene id: 875328:JDM601_RS01965
uniprot id: F5YZW8
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

875328:JDM601 RS15005
gene id: 875328:JDM601_RS15005
uniprot id: F5Z1Y5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

875328:JDM601 RS06115
gene id: 875328:JDM601_RS06115
uniprot id: F5YVW8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS08605
gene id: 875328:JDM601_RS08605
uniprot id: F5Z0Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

875328:JDM601 RS10020
gene id: 875328:JDM601_RS10020
uniprot id: F5YS25
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

875328:JDM601 RS08935
gene id: 875328:JDM601_RS08935
uniprot id: F5Z1U0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

875328:JDM601 RS06665
gene id: 875328:JDM601_RS06665
uniprot id: F5YWN4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

875328:JDM601 RS04085
gene id: 875328:JDM601_RS04085
uniprot id: F5YSH4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS19085
gene id: 875328:JDM601_RS19085
uniprot id: F5YRN1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

875328:JDM601 RS07220
gene id: 875328:JDM601_RS07220
uniprot id: F5YY48
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS15235
gene id: 875328:JDM601_RS15235
uniprot id: F5Z232
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

875328:JDM601 RS12545
gene id: 875328:JDM601_RS12545
uniprot id: F5YW82
names: Similarity
messages: Belongs to the PspA/IM30 family.

875328:JDM601 RS15875
gene id: 875328:JDM601_RS15875
uniprot id: F5Z3T7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

875328:JDM601 RS15435
gene id: 875328:JDM601_RS15435
uniprot id: F5Z2V7
names: Similarity
messages: Belongs to the TPP enzyme family.

875328:JDM601 RS03235
gene id: 875328:JDM601_RS03235
uniprot id: F5Z3C7
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

875328:JDM601 RS05445
gene id: 875328:JDM601_RS05445
uniprot id: F5YUL5
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS08075
gene id: 875328:JDM601_RS08075
uniprot id: F5YZZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

875328:JDM601 RS13100
gene id: 875328:JDM601_RS13100
uniprot id: F5YXG5
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS06130
gene id: 875328:JDM601_RS06130
uniprot id: F5YVX1
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS01480
gene id: 875328:JDM601_RS01480
uniprot id: F5YYY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EspG family.
messages: Cytoplasm

875328:JDM601 RS01215
gene id: 875328:JDM601_RS01215
uniprot id: F5YYT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

875328:JDM601 RS08340
gene id: 875328:JDM601_RS08340
uniprot id: F5Z044
names: Similarity
messages: Belongs to the AccD/PCCB family.

875328:JDM601 RS03315
gene id: 875328:JDM601_RS03315
uniprot id: F5Z3E0
names: Similarity
messages: Belongs to the CFA/CMAS family.

875328:JDM601 RS11710
gene id: 875328:JDM601_RS11710
uniprot id: F5YUU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

875328:JDM601 RS12980
gene id: 875328:JDM601_RS12980
uniprot id: F5YWX6
names: Similarity
messages: Belongs to the glutamine synthetase family.

875328:JDM601 RS10900
gene id: 875328:JDM601_RS10900
uniprot id: F5YTG7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

875328:JDM601 RS16445
gene id: 875328:JDM601_RS16445
uniprot id: F5YXS6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

875328:JDM601 RS14300
gene id: 875328:JDM601_RS14300
uniprot id: F5Z068
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

875328:JDM601 RS11595
gene id: 875328:JDM601_RS11595
uniprot id: F5YUS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

875328:JDM601 RS20530
gene id: 875328:JDM601_RS20530
uniprot id: F5YU88
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS18750
gene id: 875328:JDM601_RS18750
uniprot id: F5Z371
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS10520
gene id: 875328:JDM601_RS10520
uniprot id: F5YST4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

875328:JDM601 RS24245
gene id: 875328:JDM601_RS24245
uniprot id: F5Z3K7
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS16885
gene id: 875328:JDM601_RS16885
uniprot id: F5YYQ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

875328:JDM601 RS05920
gene id: 875328:JDM601_RS05920
uniprot id: F5YVC2
names: Similarity
messages: Belongs to the MmpS family.

875328:JDM601 RS15845
gene id: 875328:JDM601_RS15845
uniprot id: F5Z3T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS00055
gene id: 875328:JDM601_RS00055
uniprot id: F5YWA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CwsA family.
messages: Cell membrane
messages: Required for regulated cell division, cell wall synthesis and the maintenance of cell shape.

875328:JDM601 RS11010
gene id: 875328:JDM601_RS11010
uniprot id: F5YTJ1
names: Similarity
messages: Belongs to the asparaginase 1 family.

875328:JDM601 RS05035
gene id: 875328:JDM601_RS05035
uniprot id: F5YTX4
names: Similarity
messages: Belongs to the mycobacterial PPE family.

875328:JDM601 RS13785
gene id: 875328:JDM601_RS13785
uniprot id: F5YYI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

875328:JDM601 RS07765
gene id: 875328:JDM601_RS07765
uniprot id: F5YZ43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Siderophore-Fe(3+) uptake transporter (SIUT) (TC 3.A.1.21) family.
messages: Cell inner membrane
messages: Forms a heterodimer with IrtB.
messages: Membrane

875328:JDM601 RS09770
gene id: 875328:JDM601_RS09770
uniprot id: F5Z3N2
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS09840
gene id: 875328:JDM601_RS09840
uniprot id: F5Z3P8
names: Similarity
messages: Belongs to the Apa family.

875328:JDM601 RS12600
gene id: 875328:JDM601_RS12600
uniprot id: F5YW93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

875328:JDM601 RS13315
gene id: 875328:JDM601_RS13315
uniprot id: F5YXK9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

875328:JDM601 RS05200
gene id: 875328:JDM601_RS05200
uniprot id: F5YUG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

875328:JDM601 RS07305
gene id: 875328:JDM601_RS07305
uniprot id: F5YY65
names: Similarity
messages: Belongs to the FPG family.

875328:JDM601 RS18595
gene id: 875328:JDM601_RS18595
uniprot id: F5Z339
names: Similarity
messages: Belongs to the peptidase C59 family.

875328:JDM601 RS13820
gene id: 875328:JDM601_RS13820
uniprot id: F5YZ84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

875328:JDM601 RS13420
gene id: 875328:JDM601_RS13420
uniprot id: F5YYB7
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

875328:JDM601 RS06030
gene id: 875328:JDM601_RS06030
uniprot id: F5YVV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

875328:JDM601 RS14665
gene id: 875328:JDM601_RS14665
uniprot id: F5Z129
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

875328:JDM601 RS08875
gene id: 875328:JDM601_RS08875
uniprot id: F5Z1S9
names: Similarity
messages: Belongs to the UPF0098 family.

875328:JDM601 RS12340
gene id: 875328:JDM601_RS12340
uniprot id: F5YW41
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

875328:JDM601 RS04490
gene id: 875328:JDM601_RS04490
uniprot id: F5YT62
names: Similarity
messages: Belongs to the FPG family.

875328:JDM601 RS12630
gene id: 875328:JDM601_RS12630
uniprot id: F5YWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS19045
gene id: 875328:JDM601_RS19045
uniprot id: F5YRM1
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS11625
gene id: 875328:JDM601_RS11625
uniprot id: F5YUT1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

875328:JDM601 RS12900
gene id: 875328:JDM601_RS12900
uniprot id: F5YWW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

875328:JDM601 RS04440
gene id: 875328:JDM601_RS04440
uniprot id: F5YT52
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS14420
gene id: 875328:JDM601_RS14420
uniprot id: F5Z092
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

875328:JDM601 RS19775
gene id: 875328:JDM601_RS19775
uniprot id: F5YSX3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

875328:JDM601 RS01295
gene id: 875328:JDM601_RS01295
uniprot id: F5YYU5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS13350
gene id: 875328:JDM601_RS13350
uniprot id: F5YXL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

875328:JDM601 RS00910
gene id: 875328:JDM601_RS00910
uniprot id: F5YXY3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS16995
gene id: 875328:JDM601_RS16995
uniprot id: F5YZG5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS06545
gene id: 875328:JDM601_RS06545
uniprot id: F5YWL5
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS05785
gene id: 875328:JDM601_RS05785
uniprot id: F5YV95
names: Similarity
messages: Belongs to the Nudix hydrolase family.

875328:JDM601 RS11215
gene id: 875328:JDM601_RS11215
uniprot id: F5YU36
names: Similarity
messages: Belongs to the band 7/mec-2 family.

875328:JDM601 RS07595
gene id: 875328:JDM601_RS07595
uniprot id: F5YZ09
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS00640
gene id: 875328:JDM601_RS00640
uniprot id: F5YX42
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS17225
gene id: 875328:JDM601_RS17225
uniprot id: F5YZL1
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS09800
gene id: 875328:JDM601_RS09800
uniprot id: F5Z3P0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

875328:JDM601 RS12885
gene id: 875328:JDM601_RS12885
uniprot id: F5YWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

875328:JDM601 RS12805
gene id: 875328:JDM601_RS12805
uniprot id: F5YWU1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

875328:JDM601 RS11840
gene id: 875328:JDM601_RS11840
uniprot id: F5YVD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

875328:JDM601 RS10145
gene id: 875328:JDM601_RS10145
uniprot id: F5YS51
names: Subcellular Location Annotation
messages: Membrane

875328:JDM601 RS20260
gene id: 875328:JDM601_RS20260
uniprot id: F5YTM5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

875328:JDM601 RS11425
gene id: 875328:JDM601_RS11425
uniprot id: F5YU80
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

875328:JDM601 RS11070
gene id: 875328:JDM601_RS11070
uniprot id: F5YU07
names: Similarity
messages: Belongs to the cytochrome P450 family.

875328:JDM601 RS18805
gene id: 875328:JDM601_RS18805
uniprot id: F5Z382
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS00570
gene id: 875328:JDM601_RS00570
uniprot id: F5YX28
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.
messages: Belongs to the FMO family.

875328:JDM601 RS06775
gene id: 875328:JDM601_RS06775
uniprot id: F5YX74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

875328:JDM601 RS02165
gene id: 875328:JDM601_RS02165
uniprot id: F5Z0P6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

875328:JDM601 RS02895
gene id: 875328:JDM601_RS02895
uniprot id: F5Z2H2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

875328:JDM601 RS03185
gene id: 875328:JDM601_RS03185
uniprot id: F5Z3B7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

875328:JDM601 RS15865
gene id: 875328:JDM601_RS15865
uniprot id: F5Z3T5
names: Similarity
messages: Belongs to the CobH/CbiC family.

875328:JDM601 RS08105
gene id: 875328:JDM601_RS08105
uniprot id: F5YZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

875328:JDM601 RS17665
gene id: 875328:JDM601_RS17665
uniprot id: F5Z0I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

875328:JDM601 RS08705
gene id: 875328:JDM601_RS08705
uniprot id: F5Z107
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

875328:JDM601 RS11775
gene id: 875328:JDM601_RS11775
uniprot id: F5YUW1
names: Similarity
messages: Belongs to the UPF0047 family.

875328:JDM601 RS06900
gene id: 875328:JDM601_RS06900
uniprot id: F5YX98
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

875328:JDM601 RS12475
gene id: 875328:JDM601_RS12475
uniprot id: F5YW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS11185
gene id: 875328:JDM601_RS11185
uniprot id: F5YU30
names: Function
names: Subunit
messages: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates.
messages: Heterodimer of an alpha and a beta chain.

875328:JDM601 RS01340
gene id: 875328:JDM601_RS01340
uniprot id: F5YYV3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

875328:JDM601 RS23795
gene id: 875328:JDM601_RS23795
uniprot id: F5YVG4
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

875328:JDM601 RS05645
gene id: 875328:JDM601_RS05645
uniprot id: F5YV65
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

875328:JDM601 RS20415
gene id: 875328:JDM601_RS20415
uniprot id: F5YTQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

875328:JDM601 RS02535
gene id: 875328:JDM601_RS02535
uniprot id: F5Z1L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

875328:JDM601 RS04300
gene id: 875328:JDM601_RS04300
uniprot id: F5YSL6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

875328:JDM601 RS11875
gene id: 875328:JDM601_RS11875
uniprot id: F5YVE1
names: Similarity
messages: Belongs to the DapA family.

875328:JDM601 RS01495
gene id: 875328:JDM601_RS01495
uniprot id: F5YYY5
names: Similarity
messages: Belongs to the EccE family.

875328:JDM601 RS06380
gene id: 875328:JDM601_RS06380
uniprot id: F5YWI3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

875328:JDM601 RS16695
gene id: 875328:JDM601_RS16695
uniprot id: F5YYL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.