869210:MARKY RS11240
gene id: 869210:MARKY_RS11240
uniprot id: F2NRA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

869210:MARKY RS10775
gene id: 869210:MARKY_RS10775
uniprot id: F2NPT8
names: Cofactor
messages: Binds 1 FAD per subunit.

869210:MARKY RS02010
gene id: 869210:MARKY_RS02010
uniprot id: F2NKW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

869210:MARKY RS08230
gene id: 869210:MARKY_RS08230
uniprot id: F2NKC2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

869210:MARKY RS05250
gene id: 869210:MARKY_RS05250
uniprot id: F2NMA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS12060
gene id: 869210:MARKY_RS12060
uniprot id: F2NQ77
names: Similarity
messages: Belongs to the FUN14 family.

869210:MARKY RS00170
gene id: 869210:MARKY_RS00170
uniprot id: F2NKN5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

869210:MARKY RS00340
gene id: 869210:MARKY_RS00340
uniprot id: F2NKR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS06285
gene id: 869210:MARKY_RS06285
uniprot id: F2NK24
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

869210:MARKY RS01690
gene id: 869210:MARKY_RS01690
uniprot id: F2NPY5
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

869210:MARKY RS04960
gene id: 869210:MARKY_RS04960
uniprot id: F2NLB4
names: Similarity
messages: Belongs to the SCO1/2 family.

869210:MARKY RS04505
gene id: 869210:MARKY_RS04505
uniprot id: F2NQB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

869210:MARKY RS01580
gene id: 869210:MARKY_RS01580
uniprot id: F2NNQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS08685
gene id: 869210:MARKY_RS08685
uniprot id: F2NMS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

869210:MARKY RS00495
gene id: 869210:MARKY_RS00495
uniprot id: F2NKU4
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS08595
gene id: 869210:MARKY_RS08595
uniprot id: F2NMR0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

869210:MARKY RS00690
gene id: 869210:MARKY_RS00690
uniprot id: F2NLR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

869210:MARKY RS07820
gene id: 869210:MARKY_RS07820
uniprot id: F2NQS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

869210:MARKY RS04405
gene id: 869210:MARKY_RS04405
uniprot id: F2NP31
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

869210:MARKY RS04285
gene id: 869210:MARKY_RS04285
uniprot id: F2NP05
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

869210:MARKY RS06710
gene id: 869210:MARKY_RS06710
uniprot id: F2NLH9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

869210:MARKY RS03875
gene id: 869210:MARKY_RS03875
uniprot id: F2NM43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

869210:MARKY RS02800
gene id: 869210:MARKY_RS02800
uniprot id: F2NNS5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

869210:MARKY RS00685
gene id: 869210:MARKY_RS00685
uniprot id: F2NLR3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

869210:MARKY RS08925
gene id: 869210:MARKY_RS08925
uniprot id: F2NPK8
names: Similarity
messages: Belongs to the UPF0166 family.

869210:MARKY RS04880
gene id: 869210:MARKY_RS04880
uniprot id: F2NL98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

869210:MARKY RS07850
gene id: 869210:MARKY_RS07850
uniprot id: F2NQS9
names: Similarity
messages: Belongs to the peptidase S9C family.

869210:MARKY RS09775
gene id: 869210:MARKY_RS09775
uniprot id: F2NKL7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS07415
gene id: 869210:MARKY_RS07415
uniprot id: F2NPC9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

869210:MARKY RS05660
gene id: 869210:MARKY_RS05660
uniprot id: F2NP72
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS08100
gene id: 869210:MARKY_RS08100
uniprot id: F2NK96
names: Similarity
messages: Belongs to the UPF0173 family.

869210:MARKY RS04555
gene id: 869210:MARKY_RS04555
uniprot id: F2NQC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

869210:MARKY RS07480
gene id: 869210:MARKY_RS07480
uniprot id: F2NPE2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

869210:MARKY RS02585
gene id: 869210:MARKY_RS02585
uniprot id: F2NM00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

869210:MARKY RS04800
gene id: 869210:MARKY_RS04800
uniprot id: F2NQH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

869210:MARKY RS10355
gene id: 869210:MARKY_RS10355
uniprot id: F2NN44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

869210:MARKY RS02015
gene id: 869210:MARKY_RS02015
uniprot id: F2NKW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

869210:MARKY RS07890
gene id: 869210:MARKY_RS07890
uniprot id: F2NQT6
names: Similarity
messages: Belongs to the GARS family.

869210:MARKY RS09430
gene id: 869210:MARKY_RS09430
uniprot id: F2NR31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS03025
gene id: 869210:MARKY_RS03025
uniprot id: F2NNW9
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

869210:MARKY RS02020
gene id: 869210:MARKY_RS02020
uniprot id: F2NKW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

869210:MARKY RS07460
gene id: 869210:MARKY_RS07460
uniprot id: F2NPD8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

869210:MARKY RS00980
gene id: 869210:MARKY_RS00980
uniprot id: F2NNA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

869210:MARKY RS01230
gene id: 869210:MARKY_RS01230
uniprot id: F2NNI5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS01705
gene id: 869210:MARKY_RS01705
uniprot id: F2NPY8
names: Similarity
messages: Belongs to the CinA family.

869210:MARKY RS00925
gene id: 869210:MARKY_RS00925
uniprot id: F2NN99
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

869210:MARKY RS04045
gene id: 869210:MARKY_RS04045
uniprot id: F2NM75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

869210:MARKY RS00500
gene id: 869210:MARKY_RS00500
uniprot id: F2NLM8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

869210:MARKY RS00940
gene id: 869210:MARKY_RS00940
uniprot id: F2NNA2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

869210:MARKY RS00165
gene id: 869210:MARKY_RS00165
uniprot id: F2NKN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

869210:MARKY RS04620
gene id: 869210:MARKY_RS04620
uniprot id: F2NQD7
names: Similarity
messages: Belongs to the ComB family.

869210:MARKY RS05685
gene id: 869210:MARKY_RS05685
uniprot id: F2NP77
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

869210:MARKY RS01870
gene id: 869210:MARKY_RS01870
uniprot id: F2NQ20
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS09550
gene id: 869210:MARKY_RS09550
uniprot id: F2NKH4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS02110
gene id: 869210:MARKY_RS02110
uniprot id: F2NKX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

869210:MARKY RS03935
gene id: 869210:MARKY_RS03935
uniprot id: F2NM55
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

869210:MARKY RS07000
gene id: 869210:MARKY_RS07000
uniprot id: F2NMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS05545
gene id: 869210:MARKY_RS05545
uniprot id: F2NP49
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS01950
gene id: 869210:MARKY_RS01950
uniprot id: F2NKU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

869210:MARKY RS08015
gene id: 869210:MARKY_RS08015
uniprot id: F2NQW1
names: Similarity
messages: Belongs to the peptidase U62 family.

869210:MARKY RS06915
gene id: 869210:MARKY_RS06915
uniprot id: F2NLL2
names: Similarity
messages: Belongs to the ycf81 family.

869210:MARKY RS11115
gene id: 869210:MARKY_RS11115
uniprot id: F2NR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

869210:MARKY RS08065
gene id: 869210:MARKY_RS08065
uniprot id: F2NK89
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

869210:MARKY RS02895
gene id: 869210:MARKY_RS02895
uniprot id: F2NNU4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

869210:MARKY RS02845
gene id: 869210:MARKY_RS02845
uniprot id: F2NNT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

869210:MARKY RS02300
gene id: 869210:MARKY_RS02300
uniprot id: F2NL09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

869210:MARKY RS05420
gene id: 869210:MARKY_RS05420
uniprot id: F2NMD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

869210:MARKY RS04770
gene id: 869210:MARKY_RS04770
uniprot id: F2NQG7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS00815
gene id: 869210:MARKY_RS00815
uniprot id: F2NLT9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

869210:MARKY RS02260
gene id: 869210:MARKY_RS02260
uniprot id: F2NL01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

869210:MARKY RS11255
gene id: 869210:MARKY_RS11255
uniprot id: F2NRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS02065
gene id: 869210:MARKY_RS02065
uniprot id: F2NKW9
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS01390
gene id: 869210:MARKY_RS01390
uniprot id: F2NNL6
names: Similarity
messages: Belongs to the UPF0102 family.

869210:MARKY RS02150
gene id: 869210:MARKY_RS02150
uniprot id: F2NKY5
names: Similarity
messages: Belongs to the histone deacetylase family.

869210:MARKY RS05035
gene id: 869210:MARKY_RS05035
uniprot id: F2NLC9
names: Similarity
messages: Belongs to the RecO family.

869210:MARKY RS02335
gene id: 869210:MARKY_RS02335
uniprot id: F2NLU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

869210:MARKY RS09665
gene id: 869210:MARKY_RS09665
uniprot id: F2NKJ5
names: Similarity
messages: Belongs to the peptidase M16 family.

869210:MARKY RS11055
gene id: 869210:MARKY_RS11055
uniprot id: F2NR69
names: Similarity
messages: Belongs to the Lgt family.

869210:MARKY RS00770
gene id: 869210:MARKY_RS00770
uniprot id: F2NLT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS08840
gene id: 869210:MARKY_RS08840
uniprot id: F2NPJ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS10335
gene id: 869210:MARKY_RS10335
uniprot id: F2NN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

869210:MARKY RS04885
gene id: 869210:MARKY_RS04885
uniprot id: F2NL99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS02285
gene id: 869210:MARKY_RS02285
uniprot id: F2NL06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

869210:MARKY RS08020
gene id: 869210:MARKY_RS08020
uniprot id: F2NQW2
names: Similarity
messages: Belongs to the peptidase U62 family.

869210:MARKY RS03315
gene id: 869210:MARKY_RS03315
uniprot id: F2NQ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

869210:MARKY RS02630
gene id: 869210:MARKY_RS02630
uniprot id: F2NM09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

869210:MARKY RS06425
gene id: 869210:MARKY_RS06425
uniprot id: F2NK52
names: Similarity
messages: Belongs to the glutamate synthase family.

869210:MARKY RS09785
gene id: 869210:MARKY_RS09785
uniprot id: F2NKL9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

869210:MARKY RS05950
gene id: 869210:MARKY_RS05950
uniprot id: F2NQJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

869210:MARKY RS03305
gene id: 869210:MARKY_RS03305
uniprot id: F2NQ88
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

869210:MARKY RS04165
gene id: 869210:MARKY_RS04165
uniprot id: F2NNY0
names: Similarity
messages: Belongs to the asp23 family.

869210:MARKY RS05755
gene id: 869210:MARKY_RS05755
uniprot id: F2NP91
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Cytoplasm
messages: Homodimer.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

869210:MARKY RS01645
gene id: 869210:MARKY_RS01645
uniprot id: F2NPX6
names: Similarity
messages: Belongs to the RutC family.

869210:MARKY RS02810
gene id: 869210:MARKY_RS02810
uniprot id: F2NNS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

869210:MARKY RS09215
gene id: 869210:MARKY_RS09215
uniprot id: F2NQY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

869210:MARKY RS03610
gene id: 869210:MARKY_RS03610
uniprot id: F2NL57
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

869210:MARKY RS04415
gene id: 869210:MARKY_RS04415
uniprot id: F2NP33
names: Similarity
messages: Belongs to the peptidase M16 family.

869210:MARKY RS04230
gene id: 869210:MARKY_RS04230
uniprot id: F2NNZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

869210:MARKY RS03345
gene id: 869210:MARKY_RS03345
uniprot id: F2NQ95
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

869210:MARKY RS06125
gene id: 869210:MARKY_RS06125
uniprot id: F2NQM5
names: Similarity
messages: Belongs to the malate synthase family.

869210:MARKY RS04000
gene id: 869210:MARKY_RS04000
uniprot id: F2NM68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

869210:MARKY RS08475
gene id: 869210:MARKY_RS08475
uniprot id: F2NMN6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

869210:MARKY RS03020
gene id: 869210:MARKY_RS03020
uniprot id: F2NNW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

869210:MARKY RS02105
gene id: 869210:MARKY_RS02105
uniprot id: F2NKX6
names: Similarity
messages: Belongs to the thioredoxin family.

869210:MARKY RS02605
gene id: 869210:MARKY_RS02605
uniprot id: F2NM04
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

869210:MARKY RS02235
gene id: 869210:MARKY_RS02235
uniprot id: F2NL00
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS03910
gene id: 869210:MARKY_RS03910
uniprot id: F2NM50
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

869210:MARKY RS00400
gene id: 869210:MARKY_RS00400
uniprot id: F2NKS5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

869210:MARKY RS06260
gene id: 869210:MARKY_RS06260
uniprot id: F2NK19
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS08555
gene id: 869210:MARKY_RS08555
uniprot id: F2NMQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

869210:MARKY RS09870
gene id: 869210:MARKY_RS09870
uniprot id: F2NMV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

869210:MARKY RS09360
gene id: 869210:MARKY_RS09360
uniprot id: F2NR17
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

869210:MARKY RS05725
gene id: 869210:MARKY_RS05725
uniprot id: F2NP85
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

869210:MARKY RS00610
gene id: 869210:MARKY_RS00610
uniprot id: F2NLQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

869210:MARKY RS07865
gene id: 869210:MARKY_RS07865
uniprot id: F2NQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS03240
gene id: 869210:MARKY_RS03240
uniprot id: F2NQ75
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

869210:MARKY RS11250
gene id: 869210:MARKY_RS11250
uniprot id: F2NRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

869210:MARKY RS10485
gene id: 869210:MARKY_RS10485
uniprot id: F2NN69
names: Similarity
messages: Belongs to the asp23 family.

869210:MARKY RS01500
gene id: 869210:MARKY_RS01500
uniprot id: F2NNN5
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS05770
gene id: 869210:MARKY_RS05770
uniprot id: F2NP93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

869210:MARKY RS10045
gene id: 869210:MARKY_RS10045
uniprot id: F2NMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

869210:MARKY RS06170
gene id: 869210:MARKY_RS06170
uniprot id: F2NQN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

869210:MARKY RS04715
gene id: 869210:MARKY_RS04715
uniprot id: F2NQF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS00510
gene id: 869210:MARKY_RS00510
uniprot id: F2NLN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

869210:MARKY RS06345
gene id: 869210:MARKY_RS06345
uniprot id: F2NK36
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

869210:MARKY RS04360
gene id: 869210:MARKY_RS04360
uniprot id: F2NP22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

869210:MARKY RS10090
gene id: 869210:MARKY_RS10090
uniprot id: F2NMZ6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

869210:MARKY RS00405
gene id: 869210:MARKY_RS00405
uniprot id: F2NKS6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS04845
gene id: 869210:MARKY_RS04845
uniprot id: F2NL91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS04040
gene id: 869210:MARKY_RS04040
uniprot id: F2NM74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS11260
gene id: 869210:MARKY_RS11260
uniprot id: F2NRB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS00240
gene id: 869210:MARKY_RS00240
uniprot id: F2NKP6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

869210:MARKY RS10420
gene id: 869210:MARKY_RS10420
uniprot id: F2NN56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

869210:MARKY RS04265
gene id: 869210:MARKY_RS04265
uniprot id: F2NP01
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

869210:MARKY RS02640
gene id: 869210:MARKY_RS02640
uniprot id: F2NM11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

869210:MARKY RS09510
gene id: 869210:MARKY_RS09510
uniprot id: F2NKG6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

869210:MARKY RS01225
gene id: 869210:MARKY_RS01225
uniprot id: F2NNI4
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

869210:MARKY RS06570
gene id: 869210:MARKY_RS06570
uniprot id: F2NK78
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

869210:MARKY RS00365
gene id: 869210:MARKY_RS00365
uniprot id: F2NKR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

869210:MARKY RS09460
gene id: 869210:MARKY_RS09460
uniprot id: F2NR37
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS04200
gene id: 869210:MARKY_RS04200
uniprot id: F2NNY7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

869210:MARKY RS03940
gene id: 869210:MARKY_RS03940
uniprot id: F2NM56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

869210:MARKY RS01130
gene id: 869210:MARKY_RS01130
uniprot id: F2NND9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS05105
gene id: 869210:MARKY_RS05105
uniprot id: F2NLE3
names: Similarity
messages: Belongs to the glutamine synthetase family.

869210:MARKY RS03585
gene id: 869210:MARKY_RS03585
uniprot id: F2NL51
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

869210:MARKY RS01220
gene id: 869210:MARKY_RS01220
uniprot id: F2NNI3
names: Similarity
messages: Belongs to the aldolase LacD family.

869210:MARKY RS09100
gene id: 869210:MARKY_RS09100
uniprot id: F2NPN8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

869210:MARKY RS08150
gene id: 869210:MARKY_RS08150
uniprot id: F2NKA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

869210:MARKY RS04110
gene id: 869210:MARKY_RS04110
uniprot id: F2NM86
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

869210:MARKY RS09485
gene id: 869210:MARKY_RS09485
uniprot id: F2NKG0
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS10000
gene id: 869210:MARKY_RS10000
uniprot id: F2NMY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS05130
gene id: 869210:MARKY_RS05130
uniprot id: F2NLE7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

869210:MARKY RS08465
gene id: 869210:MARKY_RS08465
uniprot id: F2NMN4
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS08385
gene id: 869210:MARKY_RS08385
uniprot id: F2NKF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

869210:MARKY RS04680
gene id: 869210:MARKY_RS04680
uniprot id: F2NQE9
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS02580
gene id: 869210:MARKY_RS02580
uniprot id: F2NLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

869210:MARKY RS07660
gene id: 869210:MARKY_RS07660
uniprot id: F2NPH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

869210:MARKY RS05215
gene id: 869210:MARKY_RS05215
uniprot id: F2NM96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

869210:MARKY RS08480
gene id: 869210:MARKY_RS08480
uniprot id: F2NMN7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

869210:MARKY RS02635
gene id: 869210:MARKY_RS02635
uniprot id: F2NM10
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS09120
gene id: 869210:MARKY_RS09120
uniprot id: F2NPP2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

869210:MARKY RS10425
gene id: 869210:MARKY_RS10425
uniprot id: F2NN57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

869210:MARKY RS08040
gene id: 869210:MARKY_RS08040
uniprot id: F2NQW9
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

869210:MARKY RS09615
gene id: 869210:MARKY_RS09615
uniprot id: F2NKI5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

869210:MARKY RS09115
gene id: 869210:MARKY_RS09115
uniprot id: F2NPP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

869210:MARKY RS09320
gene id: 869210:MARKY_RS09320
uniprot id: F2NR09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

869210:MARKY RS05075
gene id: 869210:MARKY_RS05075
uniprot id: F2NLD7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

869210:MARKY RS09105
gene id: 869210:MARKY_RS09105
uniprot id: F2NPN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Periplasm

869210:MARKY RS10765
gene id: 869210:MARKY_RS10765
uniprot id: F2NPT6
names: Similarity
messages: Belongs to the peptidase M29 family.

869210:MARKY RS04780
gene id: 869210:MARKY_RS04780
uniprot id: F2NQG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS07840
gene id: 869210:MARKY_RS07840
uniprot id: F2NQS7
names: Similarity
messages: Belongs to the peptidase S41A family.

869210:MARKY RS08980
gene id: 869210:MARKY_RS08980
uniprot id: F2NPL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

869210:MARKY RS01360
gene id: 869210:MARKY_RS01360
uniprot id: F2NNL0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

869210:MARKY RS05970
gene id: 869210:MARKY_RS05970
uniprot id: F2NQJ5
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

869210:MARKY RS10935
gene id: 869210:MARKY_RS10935
uniprot id: F2NR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS05200
gene id: 869210:MARKY_RS05200
uniprot id: F2NM93
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

869210:MARKY RS09380
gene id: 869210:MARKY_RS09380
uniprot id: F2NR21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

869210:MARKY RS01985
gene id: 869210:MARKY_RS01985
uniprot id: F2NKV5
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS02385
gene id: 869210:MARKY_RS02385
uniprot id: F2NLW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

869210:MARKY RS06300
gene id: 869210:MARKY_RS06300
uniprot id: F2NK27
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

869210:MARKY RS10075
gene id: 869210:MARKY_RS10075
uniprot id: F2NMZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

869210:MARKY RS03130
gene id: 869210:MARKY_RS03130
uniprot id: F2NQ53
names: Similarity
messages: Belongs to the AlaDH/PNT family.

869210:MARKY RS09325
gene id: 869210:MARKY_RS09325
uniprot id: F2NR10
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

869210:MARKY RS05115
gene id: 869210:MARKY_RS05115
uniprot id: F2NLE5
names: Similarity
messages: Belongs to the CutA family.

869210:MARKY RS07300
gene id: 869210:MARKY_RS07300
uniprot id: F2NML6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

869210:MARKY RS08695
gene id: 869210:MARKY_RS08695
uniprot id: F2NMT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

869210:MARKY RS08075
gene id: 869210:MARKY_RS08075
uniprot id: F2NK91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

869210:MARKY RS00320
gene id: 869210:MARKY_RS00320
uniprot id: F2NKQ8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

869210:MARKY RS05810
gene id: 869210:MARKY_RS05810
uniprot id: F2NPA1
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

869210:MARKY RS01040
gene id: 869210:MARKY_RS01040
uniprot id: F2NNC1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

869210:MARKY RS00375
gene id: 869210:MARKY_RS00375
uniprot id: F2NKR9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

869210:MARKY RS09160
gene id: 869210:MARKY_RS09160
uniprot id: F2NQX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

869210:MARKY RS05805
gene id: 869210:MARKY_RS05805
uniprot id: F2NPA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

869210:MARKY RS08775
gene id: 869210:MARKY_RS08775
uniprot id: F2NMU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

869210:MARKY RS07420
gene id: 869210:MARKY_RS07420
uniprot id: F2NPD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

869210:MARKY RS04170
gene id: 869210:MARKY_RS04170
uniprot id: F2NNY1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

869210:MARKY RS05675
gene id: 869210:MARKY_RS05675
uniprot id: F2NP75
names: Similarity
messages: Belongs to the IMPACT family.

869210:MARKY RS05430
gene id: 869210:MARKY_RS05430
uniprot id: F2NMD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

869210:MARKY RS08625
gene id: 869210:MARKY_RS08625
uniprot id: F2NMR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

869210:MARKY RS00160
gene id: 869210:MARKY_RS00160
uniprot id: F2NKN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

869210:MARKY RS07015
gene id: 869210:MARKY_RS07015
uniprot id: F2NMG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869210:MARKY RS08930
gene id: 869210:MARKY_RS08930
uniprot id: F2NPK9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

869210:MARKY RS09450
gene id: 869210:MARKY_RS09450
uniprot id: F2NR35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

869210:MARKY RS08170
gene id: 869210:MARKY_RS08170
uniprot id: F2NKB1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

869210:MARKY RS01995
gene id: 869210:MARKY_RS01995
uniprot id: F2NKV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

869210:MARKY RS01570
gene id: 869210:MARKY_RS01570
uniprot id: F2NNP8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

869210:MARKY RS01965
gene id: 869210:MARKY_RS01965
uniprot id: F2NKV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

869210:MARKY RS02290
gene id: 869210:MARKY_RS02290
uniprot id: F2NL07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

869210:MARKY RS03650
gene id: 869210:MARKY_RS03650
uniprot id: F2NL65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

869210:MARKY RS10855
gene id: 869210:MARKY_RS10855
uniprot id: F2NPV4
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

869210:MARKY RS01890
gene id: 869210:MARKY_RS01890
uniprot id: F2NQ24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

869210:MARKY RS06310
gene id: 869210:MARKY_RS06310
uniprot id: F2NK29
names: Similarity
messages: Belongs to the CdaR family.

869210:MARKY RS05135
gene id: 869210:MARKY_RS05135
uniprot id: F2NLE8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

869210:MARKY RS03795
gene id: 869210:MARKY_RS03795
uniprot id: F2NM27
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS11165
gene id: 869210:MARKY_RS11165
uniprot id: F2NR91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS03210
gene id: 869210:MARKY_RS03210
uniprot id: F2NQ69
names: Similarity
messages: Belongs to the Nudix hydrolase family.

869210:MARKY RS07240
gene id: 869210:MARKY_RS07240
uniprot id: F2NMK4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

869210:MARKY RS10015
gene id: 869210:MARKY_RS10015
uniprot id: F2NMY3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

869210:MARKY RS00715
gene id: 869210:MARKY_RS00715
uniprot id: F2NLR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

869210:MARKY RS09885
gene id: 869210:MARKY_RS09885
uniprot id: F2NMW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

869210:MARKY RS03540
gene id: 869210:MARKY_RS03540
uniprot id: F2NL42
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

869210:MARKY RS06255
gene id: 869210:MARKY_RS06255
uniprot id: F2NK18
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

869210:MARKY RS09695
gene id: 869210:MARKY_RS09695
uniprot id: F2NKK1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

869210:MARKY RS01095
gene id: 869210:MARKY_RS01095
uniprot id: F2NND2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

869210:MARKY RS03360
gene id: 869210:MARKY_RS03360
uniprot id: F2NQ98
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

869210:MARKY RS02165
gene id: 869210:MARKY_RS02165
uniprot id: F2NKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

869210:MARKY RS01725
gene id: 869210:MARKY_RS01725
uniprot id: F2NPZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS07250
gene id: 869210:MARKY_RS07250
uniprot id: F2NMK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

869210:MARKY RS00850
gene id: 869210:MARKY_RS00850
uniprot id: F2NN85
names: Similarity
messages: Belongs to the PrpD family.

869210:MARKY RS05920
gene id: 869210:MARKY_RS05920
uniprot id: F2NQI6
names: Similarity
messages: Belongs to the MEMO1 family.

869210:MARKY RS04315
gene id: 869210:MARKY_RS04315
uniprot id: F2NP12
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

869210:MARKY RS01745
gene id: 869210:MARKY_RS01745
uniprot id: F2NPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

869210:MARKY RS08175
gene id: 869210:MARKY_RS08175
uniprot id: F2NKB2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869210:MARKY RS08950
gene id: 869210:MARKY_RS08950
uniprot id: F2NPL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

869210:MARKY RS02625
gene id: 869210:MARKY_RS02625
uniprot id: F2NM08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

869210:MARKY RS10155
gene id: 869210:MARKY_RS10155
uniprot id: F2NN08
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

869210:MARKY RS02045
gene id: 869210:MARKY_RS02045
uniprot id: F2NKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

869210:MARKY RS09540
gene id: 869210:MARKY_RS09540
uniprot id: F2NKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

869210:MARKY RS05750
gene id: 869210:MARKY_RS05750
uniprot id: F2NP90
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

869210:MARKY RS10430
gene id: 869210:MARKY_RS10430
uniprot id: F2NN58
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS05235
gene id: 869210:MARKY_RS05235
uniprot id: F2NMA0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

869210:MARKY RS00290
gene id: 869210:MARKY_RS00290
uniprot id: F2NKQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS07055
gene id: 869210:MARKY_RS07055
uniprot id: F2NMG9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS04805
gene id: 869210:MARKY_RS04805
uniprot id: F2NQH5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS03800
gene id: 869210:MARKY_RS03800
uniprot id: F2NM28
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

869210:MARKY RS08660
gene id: 869210:MARKY_RS08660
uniprot id: F2NMS3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

869210:MARKY RS05705
gene id: 869210:MARKY_RS05705
uniprot id: F2NP81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

869210:MARKY RS06070
gene id: 869210:MARKY_RS06070
uniprot id: F2NQL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

869210:MARKY RS03425
gene id: 869210:MARKY_RS03425
uniprot id: F2NL19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

869210:MARKY RS03440
gene id: 869210:MARKY_RS03440
uniprot id: F2NL22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869210:MARKY RS04320
gene id: 869210:MARKY_RS04320
uniprot id: F2NP13
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS01405
gene id: 869210:MARKY_RS01405
uniprot id: F2NNL9
names: Similarity
messages: Belongs to the CFA/CMAS family.

869210:MARKY RS08645
gene id: 869210:MARKY_RS08645
uniprot id: F2NMS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

869210:MARKY RS09345
gene id: 869210:MARKY_RS09345
uniprot id: F2NR14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

869210:MARKY RS09445
gene id: 869210:MARKY_RS09445
uniprot id: F2NR34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

869210:MARKY RS04760
gene id: 869210:MARKY_RS04760
uniprot id: F2NQG5
names: Similarity
messages: Belongs to the TPP enzyme family.

869210:MARKY RS04545
gene id: 869210:MARKY_RS04545
uniprot id: F2NQC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

869210:MARKY RS10410
gene id: 869210:MARKY_RS10410
uniprot id: F2NN54
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

869210:MARKY RS05360
gene id: 869210:MARKY_RS05360
uniprot id: F2NMC3
names: Similarity
messages: Belongs to the citrate synthase family.

869210:MARKY RS10630
gene id: 869210:MARKY_RS10630
uniprot id: F2NPR1
names: Similarity
messages: Belongs to the GSP E family.

869210:MARKY RS05015
gene id: 869210:MARKY_RS05015
uniprot id: F2NLC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

869210:MARKY RS06815
gene id: 869210:MARKY_RS06815
uniprot id: F2NLJ3
names: Similarity
messages: Belongs to the FemABX family.

869210:MARKY RS05000
gene id: 869210:MARKY_RS05000
uniprot id: F2NLC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

869210:MARKY RS00605
gene id: 869210:MARKY_RS00605
uniprot id: F2NLP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

869210:MARKY RS01410
gene id: 869210:MARKY_RS01410
uniprot id: F2NNM0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

869210:MARKY RS06440
gene id: 869210:MARKY_RS06440
uniprot id: F2NK55
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS05825
gene id: 869210:MARKY_RS05825
uniprot id: F2NPA4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

869210:MARKY RS08765
gene id: 869210:MARKY_RS08765
uniprot id: F2NMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

869210:MARKY RS10515
gene id: 869210:MARKY_RS10515
uniprot id: F2NN75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

869210:MARKY RS09985
gene id: 869210:MARKY_RS09985
uniprot id: F2NMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

869210:MARKY RS09350
gene id: 869210:MARKY_RS09350
uniprot id: F2NR15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

869210:MARKY RS06340
gene id: 869210:MARKY_RS06340
uniprot id: F2NK35
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

869210:MARKY RS02280
gene id: 869210:MARKY_RS02280
uniprot id: F2NL05
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

869210:MARKY RS03575
gene id: 869210:MARKY_RS03575
uniprot id: F2NL49
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

869210:MARKY RS03150
gene id: 869210:MARKY_RS03150
uniprot id: F2NQ57
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

869210:MARKY RS05415
gene id: 869210:MARKY_RS05415
uniprot id: F2NMD6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

869210:MARKY RS04370
gene id: 869210:MARKY_RS04370
uniprot id: F2NP24
names: Similarity
messages: Belongs to the RecJ family.

869210:MARKY RS10530
gene id: 869210:MARKY_RS10530
uniprot id: F2NN78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

869210:MARKY RS07515
gene id: 869210:MARKY_RS07515
uniprot id: F2NPE9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

869210:MARKY RS06325
gene id: 869210:MARKY_RS06325
uniprot id: F2NK32
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

869210:MARKY RS08045
gene id: 869210:MARKY_RS08045
uniprot id: F2NK85
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

869210:MARKY RS06535
gene id: 869210:MARKY_RS06535
uniprot id: F2NK71
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS08590
gene id: 869210:MARKY_RS08590
uniprot id: F2NMQ9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

869210:MARKY RS07290
gene id: 869210:MARKY_RS07290
uniprot id: F2NML4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS10905
gene id: 869210:MARKY_RS10905
uniprot id: F2NPW3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

869210:MARKY RS09180
gene id: 869210:MARKY_RS09180
uniprot id: F2NQX7
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS08565
gene id: 869210:MARKY_RS08565
uniprot id: F2NMQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

869210:MARKY RS09480
gene id: 869210:MARKY_RS09480
uniprot id: F2NR41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

869210:MARKY RS07500
gene id: 869210:MARKY_RS07500
uniprot id: F2NPE6
names: Similarity
messages: Belongs to the aspartokinase family.

869210:MARKY RS03570
gene id: 869210:MARKY_RS03570
uniprot id: F2NL48
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell outer membrane
messages: Membrane
messages: Periplasm

869210:MARKY RS00015
gene id: 869210:MARKY_RS00015
uniprot id: F2NNF8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

869210:MARKY RS07280
gene id: 869210:MARKY_RS07280
uniprot id: F2NML2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

869210:MARKY RS01195
gene id: 869210:MARKY_RS01195
uniprot id: F2NNF2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

869210:MARKY RS00545
gene id: 869210:MARKY_RS00545
uniprot id: F2NLN7
names: Similarity
messages: Belongs to the BshC family.

869210:MARKY RS03060
gene id: 869210:MARKY_RS03060
uniprot id: F2NQ39
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

869210:MARKY RS08630
gene id: 869210:MARKY_RS08630
uniprot id: F2NMR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

869210:MARKY RS06590
gene id: 869210:MARKY_RS06590
uniprot id: F2NK83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

869210:MARKY RS11110
gene id: 869210:MARKY_RS11110
uniprot id: F2NR80
names: Similarity
messages: Belongs to the fructosamine kinase family.

869210:MARKY RS03695
gene id: 869210:MARKY_RS03695
uniprot id: F2NL74
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

869210:MARKY RS00680
gene id: 869210:MARKY_RS00680
uniprot id: F2NLR2
names: Similarity
messages: Belongs to the DEAD box helicase family.

869210:MARKY RS04785
gene id: 869210:MARKY_RS04785
uniprot id: F2NQH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

869210:MARKY RS05860
gene id: 869210:MARKY_RS05860
uniprot id: F2NPB1
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS09435
gene id: 869210:MARKY_RS09435
uniprot id: F2NR32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS07295
gene id: 869210:MARKY_RS07295
uniprot id: F2NML5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

869210:MARKY RS02115
gene id: 869210:MARKY_RS02115
uniprot id: F2NKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

869210:MARKY RS10370
gene id: 869210:MARKY_RS10370
uniprot id: F2NN47
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS06000
gene id: 869210:MARKY_RS06000
uniprot id: F2NQK1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

869210:MARKY RS00110
gene id: 869210:MARKY_RS00110
uniprot id: F2NNH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS04235
gene id: 869210:MARKY_RS04235
uniprot id: F2NNZ5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

869210:MARKY RS04305
gene id: 869210:MARKY_RS04305
uniprot id: F2NP10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

869210:MARKY RS08240
gene id: 869210:MARKY_RS08240
uniprot id: F2NKC4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

869210:MARKY RS00055
gene id: 869210:MARKY_RS00055
uniprot id: F2NNG5
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS07030
gene id: 869210:MARKY_RS07030
uniprot id: F2NMG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

869210:MARKY RS04340
gene id: 869210:MARKY_RS04340
uniprot id: F2NP17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

869210:MARKY RS04335
gene id: 869210:MARKY_RS04335
uniprot id: F2NP16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869210:MARKY RS02085
gene id: 869210:MARKY_RS02085
uniprot id: F2NKX2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

869210:MARKY RS05800
gene id: 869210:MARKY_RS05800
uniprot id: F2NP99
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

869210:MARKY RS07895
gene id: 869210:MARKY_RS07895
uniprot id: F2NQT7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

869210:MARKY RS00700
gene id: 869210:MARKY_RS00700
uniprot id: F2NLR6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS08190
gene id: 869210:MARKY_RS08190
uniprot id: F2NKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS01135
gene id: 869210:MARKY_RS01135
uniprot id: F2NNE0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

869210:MARKY RS02555
gene id: 869210:MARKY_RS02555
uniprot id: F2NLZ4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

869210:MARKY RS09850
gene id: 869210:MARKY_RS09850
uniprot id: F2NMV3
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS01505
gene id: 869210:MARKY_RS01505
uniprot id: F2NNN6
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS07925
gene id: 869210:MARKY_RS07925
uniprot id: F2NQU3
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS09330
gene id: 869210:MARKY_RS09330
uniprot id: F2NR11
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

869210:MARKY RS06020
gene id: 869210:MARKY_RS06020
uniprot id: F2NQK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

869210:MARKY RS02775
gene id: 869210:MARKY_RS02775
uniprot id: F2NNS0
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

869210:MARKY RS10505
gene id: 869210:MARKY_RS10505
uniprot id: F2NN73
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

869210:MARKY RS02910
gene id: 869210:MARKY_RS02910
uniprot id: F2NNU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

869210:MARKY RS04515
gene id: 869210:MARKY_RS04515
uniprot id: F2NQB4
names: Subcellular Location Annotation
messages: Cytoplasm

869210:MARKY RS01940
gene id: 869210:MARKY_RS01940
uniprot id: F2NKU6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

869210:MARKY RS00535
gene id: 869210:MARKY_RS00535
uniprot id: F2NLN5
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

869210:MARKY RS10525
gene id: 869210:MARKY_RS10525
uniprot id: F2NN77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

869210:MARKY RS05925
gene id: 869210:MARKY_RS05925
uniprot id: F2NQI7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

869210:MARKY RS04510
gene id: 869210:MARKY_RS04510
uniprot id: F2NQB3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

869210:MARKY RS07335
gene id: 869210:MARKY_RS07335
uniprot id: F2NMM3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

869210:MARKY RS11305
gene id: 869210:MARKY_RS11305
uniprot id: F2NRB8
names: Similarity
messages: Belongs to the ParB family.

869210:MARKY RS02470
gene id: 869210:MARKY_RS02470
uniprot id: F2NLX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS00115
gene id: 869210:MARKY_RS00115
uniprot id: F2NNH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS02590
gene id: 869210:MARKY_RS02590
uniprot id: F2NM01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

869210:MARKY RS10825
gene id: 869210:MARKY_RS10825
uniprot id: F2NPU8
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS03815
gene id: 869210:MARKY_RS03815
uniprot id: F2NM31
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

869210:MARKY RS04015
gene id: 869210:MARKY_RS04015
uniprot id: F2NM71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

869210:MARKY RS00070
gene id: 869210:MARKY_RS00070
uniprot id: F2NNG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS03810
gene id: 869210:MARKY_RS03810
uniprot id: F2NM30
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

869210:MARKY RS04380
gene id: 869210:MARKY_RS04380
uniprot id: F2NP26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

869210:MARKY RS07770
gene id: 869210:MARKY_RS07770
uniprot id: F2NQR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

869210:MARKY RS09470
gene id: 869210:MARKY_RS09470
uniprot id: F2NR39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

869210:MARKY RS01400
gene id: 869210:MARKY_RS01400
uniprot id: F2NNL8
names: Similarity
messages: Belongs to the UbiD family.

869210:MARKY RS07785
gene id: 869210:MARKY_RS07785
uniprot id: F2NQR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

869210:MARKY RS09830
gene id: 869210:MARKY_RS09830
uniprot id: F2NKM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

869210:MARKY RS07490
gene id: 869210:MARKY_RS07490
uniprot id: F2NPE4
names: Similarity
messages: Belongs to the SufE family.

869210:MARKY RS00045
gene id: 869210:MARKY_RS00045
uniprot id: F2NNG3
names: Similarity
messages: Belongs to the universal stress protein A family.

869210:MARKY RS01365
gene id: 869210:MARKY_RS01365
uniprot id: F2NNL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

869210:MARKY RS10245
gene id: 869210:MARKY_RS10245
uniprot id: F2NN25
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

869210:MARKY RS04930
gene id: 869210:MARKY_RS04930
uniprot id: F2NLA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

869210:MARKY RS00530
gene id: 869210:MARKY_RS00530
uniprot id: F2NLN4
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

869210:MARKY RS05690
gene id: 869210:MARKY_RS05690
uniprot id: F2NP78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

869210:MARKY RS00800
gene id: 869210:MARKY_RS00800
uniprot id: F2NLT6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

869210:MARKY RS08495
gene id: 869210:MARKY_RS08495
uniprot id: F2NMP0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

869210:MARKY RS03500
gene id: 869210:MARKY_RS03500
uniprot id: F2NL34
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

869210:MARKY RS08615
gene id: 869210:MARKY_RS08615
uniprot id: F2NMR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

869210:MARKY RS05830
gene id: 869210:MARKY_RS05830
uniprot id: F2NPA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS05370
gene id: 869210:MARKY_RS05370
uniprot id: F2NMC5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

869210:MARKY RS09300
gene id: 869210:MARKY_RS09300
uniprot id: F2NR05
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

869210:MARKY RS02790
gene id: 869210:MARKY_RS02790
uniprot id: F2NNS3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

869210:MARKY RS05895
gene id: 869210:MARKY_RS05895
uniprot id: F2NQI1
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS09170
gene id: 869210:MARKY_RS09170
uniprot id: F2NQX5
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS09375
gene id: 869210:MARKY_RS09375
uniprot id: F2NR20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS05210
gene id: 869210:MARKY_RS05210
uniprot id: F2NM95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

869210:MARKY RS06090
gene id: 869210:MARKY_RS06090
uniprot id: F2NQL8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

869210:MARKY RS11160
gene id: 869210:MARKY_RS11160
uniprot id: F2NR90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS08690
gene id: 869210:MARKY_RS08690
uniprot id: F2NL01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

869210:MARKY RS03475
gene id: 869210:MARKY_RS03475
uniprot id: F2NL29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS02535
gene id: 869210:MARKY_RS02535
uniprot id: F2NLZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

869210:MARKY RS11020
gene id: 869210:MARKY_RS11020
uniprot id: F2NR62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

869210:MARKY RS10640
gene id: 869210:MARKY_RS10640
uniprot id: F2NPR3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

869210:MARKY RS01475
gene id: 869210:MARKY_RS01475
uniprot id: F2NNN0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

869210:MARKY RS11075
gene id: 869210:MARKY_RS11075
uniprot id: F2NR73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

869210:MARKY RS06060
gene id: 869210:MARKY_RS06060
uniprot id: F2NQL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

869210:MARKY RS09950
gene id: 869210:MARKY_RS09950
uniprot id: F2NMX1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS10850
gene id: 869210:MARKY_RS10850
uniprot id: F2NPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS04275
gene id: 869210:MARKY_RS04275
uniprot id: F2NP03
names: Similarity
messages: Belongs to the fabD family.

869210:MARKY RS01885
gene id: 869210:MARKY_RS01885
uniprot id: F2NQ23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

869210:MARKY RS02985
gene id: 869210:MARKY_RS02985
uniprot id: F2NNW1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

869210:MARKY RS09265
gene id: 869210:MARKY_RS09265
uniprot id: F2NQZ8
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS07310
gene id: 869210:MARKY_RS07310
uniprot id: F2NML8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

869210:MARKY RS09980
gene id: 869210:MARKY_RS09980
uniprot id: F2NMX6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

869210:MARKY RS07440
gene id: 869210:MARKY_RS07440
uniprot id: F2NPD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

869210:MARKY RS06180
gene id: 869210:MARKY_RS06180
uniprot id: F2NQN6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

869210:MARKY RS04140
gene id: 869210:MARKY_RS04140
uniprot id: F2NNX4
names: Similarity
messages: Belongs to the transketolase family.

869210:MARKY RS08560
gene id: 869210:MARKY_RS08560
uniprot id: F2NMQ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

869210:MARKY RS04345
gene id: 869210:MARKY_RS04345
uniprot id: F2NP18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

869210:MARKY RS05995
gene id: 869210:MARKY_RS05995
uniprot id: F2NQK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

869210:MARKY RS08300
gene id: 869210:MARKY_RS08300
uniprot id: F2NKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

869210:MARKY RS09810
gene id: 869210:MARKY_RS09810
uniprot id: F2NKM4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

869210:MARKY RS00215
gene id: 869210:MARKY_RS00215
uniprot id: F2NKP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

869210:MARKY RS04570
gene id: 869210:MARKY_RS04570
uniprot id: F2NQC7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

869210:MARKY RS02495
gene id: 869210:MARKY_RS02495
uniprot id: F2NLY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

869210:MARKY RS08960
gene id: 869210:MARKY_RS08960
uniprot id: F2NPL4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

869210:MARKY RS10225
gene id: 869210:MARKY_RS10225
uniprot id: F2NN22
names: Similarity
messages: Belongs to the peptidase S8 family.

869210:MARKY RS01600
gene id: 869210:MARKY_RS01600
uniprot id: F2NPW8
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS03430
gene id: 869210:MARKY_RS03430
uniprot id: F2NL20
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

869210:MARKY RS07045
gene id: 869210:MARKY_RS07045
uniprot id: F2NMG7
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

869210:MARKY RS06935
gene id: 869210:MARKY_RS06935
uniprot id: F2NLL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

869210:MARKY RS04540
gene id: 869210:MARKY_RS04540
uniprot id: F2NQC0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

869210:MARKY RS08975
gene id: 869210:MARKY_RS08975
uniprot id: F2NPL7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS08680
gene id: 869210:MARKY_RS08680
uniprot id: F2NMS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

869210:MARKY RS01285
gene id: 869210:MARKY_RS01285
uniprot id: F2NNJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS07610
gene id: 869210:MARKY_RS07610
uniprot id: F2NPG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

869210:MARKY RS04600
gene id: 869210:MARKY_RS04600
uniprot id: F2NQD3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

869210:MARKY RS08295
gene id: 869210:MARKY_RS08295
uniprot id: F2NKD5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

869210:MARKY RS02445
gene id: 869210:MARKY_RS02445
uniprot id: F2NLX2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

869210:MARKY RS04280
gene id: 869210:MARKY_RS04280
uniprot id: F2NP04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

869210:MARKY RS11130
gene id: 869210:MARKY_RS11130
uniprot id: F2NR84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

869210:MARKY RS08420
gene id: 869210:MARKY_RS08420
uniprot id: F2NMM5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

869210:MARKY RS06195
gene id: 869210:MARKY_RS06195
uniprot id: F2NQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS07190
gene id: 869210:MARKY_RS07190
uniprot id: F2NMJ6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

869210:MARKY RS04485
gene id: 869210:MARKY_RS04485
uniprot id: F2NQA8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

869210:MARKY RS05400
gene id: 869210:MARKY_RS05400
uniprot id: F2NMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

869210:MARKY RS04815
gene id: 869210:MARKY_RS04815
uniprot id: F2NL85
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

869210:MARKY RS10685
gene id: 869210:MARKY_RS10685
uniprot id: F2NPS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS08005
gene id: 869210:MARKY_RS08005
uniprot id: F2NQV9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

869210:MARKY RS00205
gene id: 869210:MARKY_RS00205
uniprot id: F2NKP2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

869210:MARKY RS00865
gene id: 869210:MARKY_RS00865
uniprot id: F2NN88
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

869210:MARKY RS03380
gene id: 869210:MARKY_RS03380
uniprot id: F2NQA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
messages: Cytoplasm

869210:MARKY RS08155
gene id: 869210:MARKY_RS08155
uniprot id: F2NKA8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS04350
gene id: 869210:MARKY_RS04350
uniprot id: F2NP20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

869210:MARKY RS06715
gene id: 869210:MARKY_RS06715
uniprot id: F2NLI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

869210:MARKY RS02830
gene id: 869210:MARKY_RS02830
uniprot id: F2NNT1
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

869210:MARKY RS07445
gene id: 869210:MARKY_RS07445
uniprot id: F2NPD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

869210:MARKY RS08965
gene id: 869210:MARKY_RS08965
uniprot id: F2NPL5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

869210:MARKY RS07235
gene id: 869210:MARKY_RS07235
uniprot id: F2NMK3
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

869210:MARKY RS08605
gene id: 869210:MARKY_RS08605
uniprot id: F2NMR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

869210:MARKY RS03895
gene id: 869210:MARKY_RS03895
uniprot id: F2NM47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for disulfide bond formation in some proteins.

869210:MARKY RS07605
gene id: 869210:MARKY_RS07605
uniprot id: F2NPG4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

869210:MARKY RS01560
gene id: 869210:MARKY_RS01560
uniprot id: F2NNP6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

869210:MARKY RS04100
gene id: 869210:MARKY_RS04100
uniprot id: F2NM84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

869210:MARKY RS08830
gene id: 869210:MARKY_RS08830
uniprot id: F2NPI9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

869210:MARKY RS00300
gene id: 869210:MARKY_RS00300
uniprot id: F2NKQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

869210:MARKY RS10295
gene id: 869210:MARKY_RS10295
uniprot id: F2NN32
names: Similarity
messages: Belongs to the PspA/IM30 family.

869210:MARKY RS00465
gene id: 869210:MARKY_RS00465
uniprot id: F2NKT8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

869210:MARKY RS04395
gene id: 869210:MARKY_RS04395
uniprot id: F2NP29
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

869210:MARKY RS08580
gene id: 869210:MARKY_RS08580
uniprot id: F2NMQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

869210:MARKY RS10620
gene id: 869210:MARKY_RS10620
uniprot id: F2NPQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

869210:MARKY RS00380
gene id: 869210:MARKY_RS00380
uniprot id: F2NKS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

869210:MARKY RS08755
gene id: 869210:MARKY_RS08755
uniprot id: F2NMU2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS07330
gene id: 869210:MARKY_RS07330
uniprot id: F2NMM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

869210:MARKY RS10875
gene id: 869210:MARKY_RS10875
uniprot id: F2NPV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

869210:MARKY RS09155
gene id: 869210:MARKY_RS09155
uniprot id: F2NQX2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS00775
gene id: 869210:MARKY_RS00775
uniprot id: F2NLT1
names: Similarity
messages: Belongs to the GSP E family.

869210:MARKY RS10435
gene id: 869210:MARKY_RS10435
uniprot id: F2NN59
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

869210:MARKY RS02920
gene id: 869210:MARKY_RS02920
uniprot id: F2NNU9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

869210:MARKY RS00575
gene id: 869210:MARKY_RS00575
uniprot id: F2NLP3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

869210:MARKY RS00615
gene id: 869210:MARKY_RS00615
uniprot id: F2NLQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

869210:MARKY RS10940
gene id: 869210:MARKY_RS10940
uniprot id: F2NR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS08270
gene id: 869210:MARKY_RS08270
uniprot id: F2NKD0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

869210:MARKY RS05445
gene id: 869210:MARKY_RS05445
uniprot id: F2NME2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

869210:MARKY RS06130
gene id: 869210:MARKY_RS06130
uniprot id: F2NQM6
names: Cofactor
messages: Can also use Mn(2+) ion.

869210:MARKY RS11610
gene id: 869210:MARKY_RS11610
uniprot id: F2NQD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

869210:MARKY RS03065
gene id: 869210:MARKY_RS03065
uniprot id: F2NQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

869210:MARKY RS01630
gene id: 869210:MARKY_RS01630
uniprot id: F2NPX3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

869210:MARKY RS01100
gene id: 869210:MARKY_RS01100
uniprot id: F2NND3
names: Similarity
messages: Belongs to the NAD synthetase family.

869210:MARKY RS05845
gene id: 869210:MARKY_RS05845
uniprot id: F2NPA8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

869210:MARKY RS06785
gene id: 869210:MARKY_RS06785
uniprot id: F2NLI9
names: Similarity
messages: Belongs to the acylphosphatase family.

869210:MARKY RS09035
gene id: 869210:MARKY_RS09035
uniprot id: F2NPM9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

869210:MARKY RS01065
gene id: 869210:MARKY_RS01065
uniprot id: F2NNC6
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS00120
gene id: 869210:MARKY_RS00120
uniprot id: F2NNH8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

869210:MARKY RS02740
gene id: 869210:MARKY_RS02740
uniprot id: F2NNR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

869210:MARKY RS01025
gene id: 869210:MARKY_RS01025
uniprot id: F2NNB8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

869210:MARKY RS08835
gene id: 869210:MARKY_RS08835
uniprot id: F2NPJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

869210:MARKY RS05645
gene id: 869210:MARKY_RS05645
uniprot id: F2NP68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

869210:MARKY RS07050
gene id: 869210:MARKY_RS07050
uniprot id: F2NMG8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

869210:MARKY RS07835
gene id: 869210:MARKY_RS07835
uniprot id: F2NQS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

869210:MARKY RS00935
gene id: 869210:MARKY_RS00935
uniprot id: F2NNA1
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

869210:MARKY RS07175
gene id: 869210:MARKY_RS07175
uniprot id: F2NMJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

869210:MARKY RS07125
gene id: 869210:MARKY_RS07125
uniprot id: F2NMI4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

869210:MARKY RS03125
gene id: 869210:MARKY_RS03125
uniprot id: F2NQ52
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

869210:MARKY RS06905
gene id: 869210:MARKY_RS06905
uniprot id: F2NLL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

869210:MARKY RS02780
gene id: 869210:MARKY_RS02780
uniprot id: F2NNS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS02520
gene id: 869210:MARKY_RS02520
uniprot id: F2NLY7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

869210:MARKY RS03170
gene id: 869210:MARKY_RS03170
uniprot id: F2NQ61
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS08185
gene id: 869210:MARKY_RS08185
uniprot id: F2NKB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS06920
gene id: 869210:MARKY_RS06920
uniprot id: F2NLL3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

869210:MARKY RS06110
gene id: 869210:MARKY_RS06110
uniprot id: F2NQM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS05630
gene id: 869210:MARKY_RS05630
uniprot id: F2NP65
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

869210:MARKY RS05255
gene id: 869210:MARKY_RS05255
uniprot id: F2NMA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS03985
gene id: 869210:MARKY_RS03985
uniprot id: F2NM65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

869210:MARKY RS10375
gene id: 869210:MARKY_RS10375
uniprot id: F2NN48
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS05405
gene id: 869210:MARKY_RS05405
uniprot id: F2NMD4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

869210:MARKY RS06045
gene id: 869210:MARKY_RS06045
uniprot id: F2NQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

869210:MARKY RS04310
gene id: 869210:MARKY_RS04310
uniprot id: F2NP11
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

869210:MARKY RS09495
gene id: 869210:MARKY_RS09495
uniprot id: F2NKG2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

869210:MARKY RS09455
gene id: 869210:MARKY_RS09455
uniprot id: F2NR36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

869210:MARKY RS03600
gene id: 869210:MARKY_RS03600
uniprot id: F2NL55
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

869210:MARKY RS05580
gene id: 869210:MARKY_RS05580
uniprot id: F2NP56
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS06925
gene id: 869210:MARKY_RS06925
uniprot id: F2NLL4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

869210:MARKY RS03710
gene id: 869210:MARKY_RS03710
uniprot id: F2NL77
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

869210:MARKY RS08245
gene id: 869210:MARKY_RS08245
uniprot id: F2NKC5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

869210:MARKY RS02120
gene id: 869210:MARKY_RS02120
uniprot id: F2NKX9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

869210:MARKY RS07805
gene id: 869210:MARKY_RS07805
uniprot id: F2NQS0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

869210:MARKY RS03055
gene id: 869210:MARKY_RS03055
uniprot id: F2NQ38
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS01525
gene id: 869210:MARKY_RS01525
uniprot id: F2NNP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

869210:MARKY RS09195
gene id: 869210:MARKY_RS09195
uniprot id: F2NQY4
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS08670
gene id: 869210:MARKY_RS08670
uniprot id: F2NMS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

869210:MARKY RS04010
gene id: 869210:MARKY_RS04010
uniprot id: F2NM70
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

869210:MARKY RS01380
gene id: 869210:MARKY_RS01380
uniprot id: F2NNL4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

869210:MARKY RS01355
gene id: 869210:MARKY_RS01355
uniprot id: F2NNK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

869210:MARKY RS01140
gene id: 869210:MARKY_RS01140
uniprot id: F2NNE1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

869210:MARKY RS02880
gene id: 869210:MARKY_RS02880
uniprot id: F2NNU1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

869210:MARKY RS08050
gene id: 869210:MARKY_RS08050
uniprot id: F2NK86
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

869210:MARKY RS04260
gene id: 869210:MARKY_RS04260
uniprot id: F2NP00
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

869210:MARKY RS03870
gene id: 869210:MARKY_RS03870
uniprot id: F2NM42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

869210:MARKY RS06160
gene id: 869210:MARKY_RS06160
uniprot id: F2NQN2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS07615
gene id: 869210:MARKY_RS07615
uniprot id: F2NPG6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS03030
gene id: 869210:MARKY_RS03030
uniprot id: F2NQ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

869210:MARKY RS10180
gene id: 869210:MARKY_RS10180
uniprot id: F2NN13
names: Similarity
messages: Belongs to the UPF0047 family.

869210:MARKY RS06375
gene id: 869210:MARKY_RS06375
uniprot id: F2NK42
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

869210:MARKY RS11195
gene id: 869210:MARKY_RS11195
uniprot id: F2NR97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS07635
gene id: 869210:MARKY_RS07635
uniprot id: F2NPH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS02885
gene id: 869210:MARKY_RS02885
uniprot id: F2NNU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

869210:MARKY RS08325
gene id: 869210:MARKY_RS08325
uniprot id: F2NKE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

869210:MARKY RS06940
gene id: 869210:MARKY_RS06940
uniprot id: F2NLL7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS05070
gene id: 869210:MARKY_RS05070
uniprot id: F2NLD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS06355
gene id: 869210:MARKY_RS06355
uniprot id: F2NK38
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS06910
gene id: 869210:MARKY_RS06910
uniprot id: F2NLL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

869210:MARKY RS01680
gene id: 869210:MARKY_RS01680
uniprot id: F2NPY3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

869210:MARKY RS01190
gene id: 869210:MARKY_RS01190
uniprot id: F2NNF1
names: Similarity
messages: Belongs to the arginase family.

869210:MARKY RS04005
gene id: 869210:MARKY_RS04005
uniprot id: F2NM69
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

869210:MARKY RS00675
gene id: 869210:MARKY_RS00675
uniprot id: F2NLR1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

869210:MARKY RS04625
gene id: 869210:MARKY_RS04625
uniprot id: F2NQD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

869210:MARKY RS08280
gene id: 869210:MARKY_RS08280
uniprot id: F2NKD2
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

869210:MARKY RS00210
gene id: 869210:MARKY_RS00210
uniprot id: F2NKP3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

869210:MARKY RS01150
gene id: 869210:MARKY_RS01150
uniprot id: F2NNE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS07245
gene id: 869210:MARKY_RS07245
uniprot id: F2NMK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

869210:MARKY RS06420
gene id: 869210:MARKY_RS06420
uniprot id: F2NK51
names: Similarity
messages: Belongs to the peptidase S1C family.

869210:MARKY RS08330
gene id: 869210:MARKY_RS08330
uniprot id: F2NKE2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

869210:MARKY RS06640
gene id: 869210:MARKY_RS06640
uniprot id: F2NLG5
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

869210:MARKY RS05475
gene id: 869210:MARKY_RS05475
uniprot id: F2NME8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

869210:MARKY RS08135
gene id: 869210:MARKY_RS08135
uniprot id: F2NKA4
names: Similarity
messages: Belongs to the cytochrome b560 family.

869210:MARKY RS01540
gene id: 869210:MARKY_RS01540
uniprot id: F2NNP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

869210:MARKY RS06965
gene id: 869210:MARKY_RS06965
uniprot id: F2NLM2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

869210:MARKY RS09880
gene id: 869210:MARKY_RS09880
uniprot id: F2NMV9
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS06115
gene id: 869210:MARKY_RS06115
uniprot id: F2NQM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS09570
gene id: 869210:MARKY_RS09570
uniprot id: F2NKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

869210:MARKY RS02930
gene id: 869210:MARKY_RS02930
uniprot id: F2NNV1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

869210:MARKY RS10665
gene id: 869210:MARKY_RS10665
uniprot id: F2NPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

869210:MARKY RS08650
gene id: 869210:MARKY_RS08650
uniprot id: F2NMS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

869210:MARKY RS00820
gene id: 869210:MARKY_RS00820
uniprot id: F2NLU0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

869210:MARKY RS09280
gene id: 869210:MARKY_RS09280
uniprot id: F2NR01
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

869210:MARKY RS02480
gene id: 869210:MARKY_RS02480
uniprot id: F2NLX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS06360
gene id: 869210:MARKY_RS06360
uniprot id: F2NK39
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS10625
gene id: 869210:MARKY_RS10625
uniprot id: F2NPR0
names: Similarity
messages: Belongs to the GSP E family.

869210:MARKY RS02620
gene id: 869210:MARKY_RS02620
uniprot id: F2NM07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

869210:MARKY RS09675
gene id: 869210:MARKY_RS09675
uniprot id: F2NKJ7
names: Similarity
messages: Belongs to the group II decarboxylase family.

869210:MARKY RS09055
gene id: 869210:MARKY_RS09055
uniprot id: F2NPN3
names: Similarity
messages: Belongs to the peptidase S8 family.

869210:MARKY RS00105
gene id: 869210:MARKY_RS00105
uniprot id: F2NNH5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS05290
gene id: 869210:MARKY_RS05290
uniprot id: F2NMA9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

869210:MARKY RS07025
gene id: 869210:MARKY_RS07025
uniprot id: F2NMG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

869210:MARKY RS06960
gene id: 869210:MARKY_RS06960
uniprot id: F2NLM1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

869210:MARKY RS03920
gene id: 869210:MARKY_RS03920
uniprot id: F2NM52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

869210:MARKY RS09995
gene id: 869210:MARKY_RS09995
uniprot id: F2NMX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS06600
gene id: 869210:MARKY_RS06600
uniprot id: F2NLF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS03390
gene id: 869210:MARKY_RS03390
uniprot id: F2NQA4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS05795
gene id: 869210:MARKY_RS05795
uniprot id: F2NP98
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS10820
gene id: 869210:MARKY_RS10820
uniprot id: F2NPU7
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS04155
gene id: 869210:MARKY_RS04155
uniprot id: F2NNX8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

869210:MARKY RS08610
gene id: 869210:MARKY_RS08610
uniprot id: F2NMR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

869210:MARKY RS04435
gene id: 869210:MARKY_RS04435
uniprot id: F2NP37
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

869210:MARKY RS06140
gene id: 869210:MARKY_RS06140
uniprot id: F2NQM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS10345
gene id: 869210:MARKY_RS10345
uniprot id: F2NN42
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

869210:MARKY RS05410
gene id: 869210:MARKY_RS05410
uniprot id: F2NMD5
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

869210:MARKY RS10240
gene id: 869210:MARKY_RS10240
uniprot id: F2NN24
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

869210:MARKY RS08700
gene id: 869210:MARKY_RS08700
uniprot id: F2NMT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

869210:MARKY RS10310
gene id: 869210:MARKY_RS10310
uniprot id: F2NN35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

869210:MARKY RS11445
gene id: 869210:MARKY_RS11445
uniprot id: F2NKF2
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS10510
gene id: 869210:MARKY_RS10510
uniprot id: F2NN74
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

869210:MARKY RS01000
gene id: 869210:MARKY_RS01000
uniprot id: F2NNB3
names: Similarity
messages: Belongs to the archease family.

869210:MARKY RS05465
gene id: 869210:MARKY_RS05465
uniprot id: F2NME6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

869210:MARKY RS09920
gene id: 869210:MARKY_RS09920
uniprot id: F2NMW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

869210:MARKY RS03355
gene id: 869210:MARKY_RS03355
uniprot id: F2NQ97
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

869210:MARKY RS00515
gene id: 869210:MARKY_RS00515
uniprot id: F2NLN1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

869210:MARKY RS08585
gene id: 869210:MARKY_RS08585
uniprot id: F2NMQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

869210:MARKY RS03995
gene id: 869210:MARKY_RS03995
uniprot id: F2NM67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

869210:MARKY RS06200
gene id: 869210:MARKY_RS06200
uniprot id: F2NQP0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

869210:MARKY RS03405
gene id: 869210:MARKY_RS03405
uniprot id: F2NL15
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

869210:MARKY RS07875
gene id: 869210:MARKY_RS07875
uniprot id: F2NQT4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

869210:MARKY RS00455
gene id: 869210:MARKY_RS00455
uniprot id: F2NKT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

869210:MARKY RS01910
gene id: 869210:MARKY_RS01910
uniprot id: F2NQ28
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

869210:MARKY RS08655
gene id: 869210:MARKY_RS08655
uniprot id: F2NMS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

869210:MARKY RS08785
gene id: 869210:MARKY_RS08785
uniprot id: F2NMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS08665
gene id: 869210:MARKY_RS08665
uniprot id: F2NMS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

869210:MARKY RS07120
gene id: 869210:MARKY_RS07120
uniprot id: F2NMI3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

869210:MARKY RS08635
gene id: 869210:MARKY_RS08635
uniprot id: F2NMR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

869210:MARKY RS04855
gene id: 869210:MARKY_RS04855
uniprot id: F2NL93
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

869210:MARKY RS08550
gene id: 869210:MARKY_RS08550
uniprot id: F2NMQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

869210:MARKY RS07880
gene id: 869210:MARKY_RS07880
uniprot id: F2NQT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

869210:MARKY RS07165
gene id: 869210:MARKY_RS07165
uniprot id: F2NMJ1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS09520
gene id: 869210:MARKY_RS09520
uniprot id: F2NKG8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

869210:MARKY RS07410
gene id: 869210:MARKY_RS07410
uniprot id: F2NPC8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

869210:MARKY RS11320
gene id: 869210:MARKY_RS11320
uniprot id: F2NRC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

869210:MARKY RS01835
gene id: 869210:MARKY_RS01835
uniprot id: F2NQ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

869210:MARKY RS08575
gene id: 869210:MARKY_RS08575
uniprot id: F2NMQ6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

869210:MARKY RS06615
gene id: 869210:MARKY_RS06615
uniprot id: F2NLG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

869210:MARKY RS04795
gene id: 869210:MARKY_RS04795
uniprot id: F2NQH3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

869210:MARKY RS00740
gene id: 869210:MARKY_RS00740
uniprot id: F2NLS3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS08120
gene id: 869210:MARKY_RS08120
uniprot id: F2NKA1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

869210:MARKY RS08130
gene id: 869210:MARKY_RS08130
uniprot id: F2NKA3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

869210:MARKY RS07975
gene id: 869210:MARKY_RS07975
uniprot id: F2NQV3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

869210:MARKY RS10520
gene id: 869210:MARKY_RS10520
uniprot id: F2NN76
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

869210:MARKY RS00330
gene id: 869210:MARKY_RS00330
uniprot id: F2NKR0
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

869210:MARKY RS01465
gene id: 869210:MARKY_RS01465
uniprot id: F2NNM8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

869210:MARKY RS10010
gene id: 869210:MARKY_RS10010
uniprot id: F2NMY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

869210:MARKY RS04585
gene id: 869210:MARKY_RS04585
uniprot id: F2NQD0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

869210:MARKY RS04645
gene id: 869210:MARKY_RS04645
uniprot id: F2NQE2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

869210:MARKY RS09725
gene id: 869210:MARKY_RS09725
uniprot id: F2NKK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

869210:MARKY RS02275
gene id: 869210:MARKY_RS02275
uniprot id: F2NL04
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

869210:MARKY RS03560
gene id: 869210:MARKY_RS03560
uniprot id: F2NL46
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

869210:MARKY RS04825
gene id: 869210:MARKY_RS04825
uniprot id: F2NL87
names: Similarity
messages: Belongs to the ComB family.

869210:MARKY RS07090
gene id: 869210:MARKY_RS07090
uniprot id: F2NMH6
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS10030
gene id: 869210:MARKY_RS10030
uniprot id: F2NMY6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

869210:MARKY RS09490
gene id: 869210:MARKY_RS09490
uniprot id: F2NKG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS07020
gene id: 869210:MARKY_RS07020
uniprot id: F2NMG2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

869210:MARKY RS02295
gene id: 869210:MARKY_RS02295
uniprot id: F2NL08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

869210:MARKY RS09295
gene id: 869210:MARKY_RS09295
uniprot id: F2NR04
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

869210:MARKY RS02200
gene id: 869210:MARKY_RS02200
uniprot id: F2NKZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

869210:MARKY RS07830
gene id: 869210:MARKY_RS07830
uniprot id: F2NQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

869210:MARKY RS05305
gene id: 869210:MARKY_RS05305
uniprot id: F2NMB2
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

869210:MARKY RS08545
gene id: 869210:MARKY_RS08545
uniprot id: F2NMQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

869210:MARKY RS00600
gene id: 869210:MARKY_RS00600
uniprot id: F2NLP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

869210:MARKY RS08740
gene id: 869210:MARKY_RS08740
uniprot id: F2NMT9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS06040
gene id: 869210:MARKY_RS06040
uniprot id: F2NQK8
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

869210:MARKY RS04810
gene id: 869210:MARKY_RS04810
uniprot id: F2NQH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

869210:MARKY RS01470
gene id: 869210:MARKY_RS01470
uniprot id: F2NNM9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

869210:MARKY RS04790
gene id: 869210:MARKY_RS04790
uniprot id: F2NQH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

869210:MARKY RS01595
gene id: 869210:MARKY_RS01595
uniprot id: F2NPW7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

869210:MARKY RS09050
gene id: 869210:MARKY_RS09050
uniprot id: F2NPN2
names: Similarity
messages: Belongs to the peptidase S8 family.

869210:MARKY RS11000
gene id: 869210:MARKY_RS11000
uniprot id: F2NR58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

869210:MARKY RS02550
gene id: 869210:MARKY_RS02550
uniprot id: F2NLZ3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

869210:MARKY RS02425
gene id: 869210:MARKY_RS02425
uniprot id: F2NLW8
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS01275
gene id: 869210:MARKY_RS01275
uniprot id: F2NNJ4
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

869210:MARKY RS00790
gene id: 869210:MARKY_RS00790
uniprot id: F2NLT4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

869210:MARKY RS06165
gene id: 869210:MARKY_RS06165
uniprot id: F2NQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

869210:MARKY RS01415
gene id: 869210:MARKY_RS01415
uniprot id: F2NNM1
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

869210:MARKY RS02570
gene id: 869210:MARKY_RS02570
uniprot id: F2NLZ7
names: Similarity
messages: Belongs to the TlyA family.

869210:MARKY RS01990
gene id: 869210:MARKY_RS01990
uniprot id: F2NKV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

869210:MARKY RS06400
gene id: 869210:MARKY_RS06400
uniprot id: F2NK47
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

869210:MARKY RS01710
gene id: 869210:MARKY_RS01710
uniprot id: F2NPY9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

869210:MARKY RS06065
gene id: 869210:MARKY_RS06065
uniprot id: F2NQL3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

869210:MARKY RS04965
gene id: 869210:MARKY_RS04965
uniprot id: F2NLB5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS01435
gene id: 869210:MARKY_RS01435
uniprot id: F2NNM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

869210:MARKY RS09515
gene id: 869210:MARKY_RS09515
uniprot id: F2NKG7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

869210:MARKY RS01370
gene id: 869210:MARKY_RS01370
uniprot id: F2NNL2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

869210:MARKY RS02195
gene id: 869210:MARKY_RS02195
uniprot id: F2NKZ4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

869210:MARKY RS05975
gene id: 869210:MARKY_RS05975
uniprot id: F2NQJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

869210:MARKY RS02395
gene id: 869210:MARKY_RS02395
uniprot id: F2NLW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

869210:MARKY RS01305
gene id: 869210:MARKY_RS01305
uniprot id: F2NNK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

869210:MARKY RS01935
gene id: 869210:MARKY_RS01935
uniprot id: F2NKU5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

869210:MARKY RS02545
gene id: 869210:MARKY_RS02545
uniprot id: F2NLZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

869210:MARKY RS07195
gene id: 869210:MARKY_RS07195
uniprot id: F2NMJ7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

869210:MARKY RS07315
gene id: 869210:MARKY_RS07315
uniprot id: F2NML9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

869210:MARKY RS08470
gene id: 869210:MARKY_RS08470
uniprot id: F2NMN5
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

869210:MARKY RS09220
gene id: 869210:MARKY_RS09220
uniprot id: F2NQY9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

869210:MARKY RS03850
gene id: 869210:MARKY_RS03850
uniprot id: F2NM38
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS05470
gene id: 869210:MARKY_RS05470
uniprot id: F2NME7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

869210:MARKY RS08490
gene id: 869210:MARKY_RS08490
uniprot id: F2NMN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

869210:MARKY RS01215
gene id: 869210:MARKY_RS01215
uniprot id: F2NNI2
names: Similarity
messages: Belongs to the GSP E family.

869210:MARKY RS08570
gene id: 869210:MARKY_RS08570
uniprot id: F2NMQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

869210:MARKY RS10760
gene id: 869210:MARKY_RS10760
uniprot id: F2NPT5
names: Similarity
messages: Belongs to the peptidase C40 family.

869210:MARKY RS02450
gene id: 869210:MARKY_RS02450
uniprot id: F2NLX3
names: Similarity
messages: Belongs to the histone deacetylase family.

869210:MARKY RS07665
gene id: 869210:MARKY_RS07665
uniprot id: F2NPH6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

869210:MARKY RS03295
gene id: 869210:MARKY_RS03295
uniprot id: F2NQ86
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

869210:MARKY RS01755
gene id: 869210:MARKY_RS01755
uniprot id: F2NPZ8
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

869210:MARKY RS04445
gene id: 869210:MARKY_RS04445
uniprot id: F2NP39
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

869210:MARKY RS07455
gene id: 869210:MARKY_RS07455
uniprot id: F2NPD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

869210:MARKY RS07675
gene id: 869210:MARKY_RS07675
uniprot id: F2NPH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

869210:MARKY RS06795
gene id: 869210:MARKY_RS06795
uniprot id: F2NLJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

869210:MARKY RS01735
gene id: 869210:MARKY_RS01735
uniprot id: F2NPZ4
names: Function
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

869210:MARKY RS04120
gene id: 869210:MARKY_RS04120
uniprot id: F2NNX0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

869210:MARKY RS04160
gene id: 869210:MARKY_RS04160
uniprot id: F2NNX9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

869210:MARKY RS10730
gene id: 869210:MARKY_RS10730
uniprot id: F2NPS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

869210:MARKY RS01060
gene id: 869210:MARKY_RS01060
uniprot id: F2NNC5
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS05670
gene id: 869210:MARKY_RS05670
uniprot id: F2NP74
names: Similarity
messages: Belongs to the CapA family.

869210:MARKY RS03830
gene id: 869210:MARKY_RS03830
uniprot id: F2NM34
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

869210:MARKY RS10290
gene id: 869210:MARKY_RS10290
uniprot id: F2NN31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

869210:MARKY RS05635
gene id: 869210:MARKY_RS05635
uniprot id: F2NP66
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS08600
gene id: 869210:MARKY_RS08600
uniprot id: F2NMR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

869210:MARKY RS03400
gene id: 869210:MARKY_RS03400
uniprot id: F2NL14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS02265
gene id: 869210:MARKY_RS02265
uniprot id: F2NL02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

869210:MARKY RS02515
gene id: 869210:MARKY_RS02515
uniprot id: F2NLY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS03435
gene id: 869210:MARKY_RS03435
uniprot id: F2NL21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

869210:MARKY RS09405
gene id: 869210:MARKY_RS09405
uniprot id: F2NR26
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

869210:MARKY RS04710
gene id: 869210:MARKY_RS04710
uniprot id: F2NQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS10540
gene id: 869210:MARKY_RS10540
uniprot id: F2NN80
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS03310
gene id: 869210:MARKY_RS03310
uniprot id: F2NQ89
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

869210:MARKY RS09355
gene id: 869210:MARKY_RS09355
uniprot id: F2NR16
names: Subcellular Location Annotation
messages: Nucleus

869210:MARKY RS07970
gene id: 869210:MARKY_RS07970
uniprot id: F2NQV2
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS09530
gene id: 869210:MARKY_RS09530
uniprot id: F2NKH0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

869210:MARKY RS03835
gene id: 869210:MARKY_RS03835
uniprot id: F2NM35
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

869210:MARKY RS02160
gene id: 869210:MARKY_RS02160
uniprot id: F2NKY7
names: Similarity
messages: Belongs to the PGI/PMI family.

869210:MARKY RS06410
gene id: 869210:MARKY_RS06410
uniprot id: F2NK49
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

869210:MARKY RS00135
gene id: 869210:MARKY_RS00135
uniprot id: F2NNI1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

869210:MARKY RS01975
gene id: 869210:MARKY_RS01975
uniprot id: F2NKV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

869210:MARKY RS08850
gene id: 869210:MARKY_RS08850
uniprot id: F2NPJ3
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS05870
gene id: 869210:MARKY_RS05870
uniprot id: F2NPB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

869210:MARKY RS01795
gene id: 869210:MARKY_RS01795
uniprot id: F2NQ04
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

869210:MARKY RS06150
gene id: 869210:MARKY_RS06150
uniprot id: F2NQN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

869210:MARKY RS02615
gene id: 869210:MARKY_RS02615
uniprot id: F2NM06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

869210:MARKY RS05720
gene id: 869210:MARKY_RS05720
uniprot id: F2NP84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

869210:MARKY RS00845
gene id: 869210:MARKY_RS00845
uniprot id: F2NN84
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

869210:MARKY RS09815
gene id: 869210:MARKY_RS09815
uniprot id: F2NKM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

869210:MARKY RS08235
gene id: 869210:MARKY_RS08235
uniprot id: F2NKC3
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS04895
gene id: 869210:MARKY_RS04895
uniprot id: F2NLA1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

869210:MARKY RS09855
gene id: 869210:MARKY_RS09855
uniprot id: F2NMV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS05990
gene id: 869210:MARKY_RS05990
uniprot id: F2NQJ9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS07205
gene id: 869210:MARKY_RS07205
uniprot id: F2NMJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

869210:MARKY RS07065
gene id: 869210:MARKY_RS07065
uniprot id: F2NMH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

869210:MARKY RS08940
gene id: 869210:MARKY_RS08940
uniprot id: F2NPL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

869210:MARKY RS04830
gene id: 869210:MARKY_RS04830
uniprot id: F2NL88
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

869210:MARKY RS02190
gene id: 869210:MARKY_RS02190
uniprot id: F2NKZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS07285
gene id: 869210:MARKY_RS07285
uniprot id: F2NML3
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS04115
gene id: 869210:MARKY_RS04115
uniprot id: F2NM87
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

869210:MARKY RS06750
gene id: 869210:MARKY_RS06750
uniprot id: F2NLI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS00395
gene id: 869210:MARKY_RS00395
uniprot id: F2NKS4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

869210:MARKY RS04525
gene id: 869210:MARKY_RS04525
uniprot id: F2NQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

869210:MARKY RS10895
gene id: 869210:MARKY_RS10895
uniprot id: F2NPW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

869210:MARKY RS07965
gene id: 869210:MARKY_RS07965
uniprot id: F2NQV1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

869210:MARKY RS04270
gene id: 869210:MARKY_RS04270
uniprot id: F2NP02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

869210:MARKY RS10020
gene id: 869210:MARKY_RS10020
uniprot id: F2NMY4
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

869210:MARKY RS09475
gene id: 869210:MARKY_RS09475
uniprot id: F2NR40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS06380
gene id: 869210:MARKY_RS06380
uniprot id: F2NK43
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

869210:MARKY RS00890
gene id: 869210:MARKY_RS00890
uniprot id: F2NN93
names: Subcellular Location Annotation
messages: Nucleus

869210:MARKY RS08535
gene id: 869210:MARKY_RS08535
uniprot id: F2NMP8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

869210:MARKY RS06695
gene id: 869210:MARKY_RS06695
uniprot id: F2NLH6
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

869210:MARKY RS07625
gene id: 869210:MARKY_RS07625
uniprot id: F2NPG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS05540
gene id: 869210:MARKY_RS05540
uniprot id: F2NP48
names: Similarity
messages: Belongs to the GreA/GreB family.

869210:MARKY RS03905
gene id: 869210:MARKY_RS03905
uniprot id: F2NM49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

869210:MARKY RS05680
gene id: 869210:MARKY_RS05680
uniprot id: F2NP76
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

869210:MARKY RS00720
gene id: 869210:MARKY_RS00720
uniprot id: F2NLS0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

869210:MARKY RS07670
gene id: 869210:MARKY_RS07670
uniprot id: F2NPH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

869210:MARKY RS03135
gene id: 869210:MARKY_RS03135
uniprot id: F2NQ54
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

869210:MARKY RS02185
gene id: 869210:MARKY_RS02185
uniprot id: F2NKZ2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

869210:MARKY RS00315
gene id: 869210:MARKY_RS00315
uniprot id: F2NKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS03245
gene id: 869210:MARKY_RS03245
uniprot id: F2NQ76
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

869210:MARKY RS02735
gene id: 869210:MARKY_RS02735
uniprot id: F2NNR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

869210:MARKY RS02370
gene id: 869210:MARKY_RS02370
uniprot id: F2NLV6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

869210:MARKY RS02390
gene id: 869210:MARKY_RS02390
uniprot id: F2NLW1
names: Similarity
messages: Belongs to the MreC family.

869210:MARKY RS07390
gene id: 869210:MARKY_RS07390
uniprot id: F2NPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS11475
gene id: 869210:MARKY_RS11475
uniprot id: F2NR25
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

869210:MARKY RS04055
gene id: 869210:MARKY_RS04055
uniprot id: F2NM77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

869210:MARKY RS06275
gene id: 869210:MARKY_RS06275
uniprot id: F2NK22
names: Similarity
messages: Belongs to the AlaDH/PNT family.

869210:MARKY RS05985
gene id: 869210:MARKY_RS05985
uniprot id: F2NQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

869210:MARKY RS06085
gene id: 869210:MARKY_RS06085
uniprot id: F2NQL7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

869210:MARKY RS04225
gene id: 869210:MARKY_RS04225
uniprot id: F2NNZ3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

869210:MARKY RS05555
gene id: 869210:MARKY_RS05555
uniprot id: F2NP51
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

869210:MARKY RS07395
gene id: 869210:MARKY_RS07395
uniprot id: F2NPC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS00660
gene id: 869210:MARKY_RS00660
uniprot id: F2NLR0
names: Similarity
messages: Belongs to the TrpF family.

869210:MARKY RS06530
gene id: 869210:MARKY_RS06530
uniprot id: F2NK70
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS01515
gene id: 869210:MARKY_RS01515
uniprot id: F2NNN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

869210:MARKY RS10975
gene id: 869210:MARKY_RS10975
uniprot id: F2NR53
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS05640
gene id: 869210:MARKY_RS05640
uniprot id: F2NP67
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

869210:MARKY RS10200
gene id: 869210:MARKY_RS10200
uniprot id: F2NN17
names: Similarity
messages: Belongs to the peptidase S58 family.

869210:MARKY RS00730
gene id: 869210:MARKY_RS00730
uniprot id: F2NLS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

869210:MARKY RS08895
gene id: 869210:MARKY_RS08895
uniprot id: F2NPK2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

869210:MARKY RS05095
gene id: 869210:MARKY_RS05095
uniprot id: F2NLE1
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS02375
gene id: 869210:MARKY_RS02375
uniprot id: F2NLV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

869210:MARKY RS08160
gene id: 869210:MARKY_RS08160
uniprot id: F2NKA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

869210:MARKY RS02485
gene id: 869210:MARKY_RS02485
uniprot id: F2NLY0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-64 and Arg-67) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

869210:MARKY RS07075
gene id: 869210:MARKY_RS07075
uniprot id: F2NMH3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS11275
gene id: 869210:MARKY_RS11275
uniprot id: F2NRB3
names: Similarity
messages: Belongs to the threonine aldolase family.

869210:MARKY RS05885
gene id: 869210:MARKY_RS05885
uniprot id: F2NQH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

869210:MARKY RS08125
gene id: 869210:MARKY_RS08125
uniprot id: F2NKA2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

869210:MARKY RS01635
gene id: 869210:MARKY_RS01635
uniprot id: F2NPX4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

869210:MARKY RS09840
gene id: 869210:MARKY_RS09840
uniprot id: F2NMV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

869210:MARKY RS00885
gene id: 869210:MARKY_RS00885
uniprot id: F2NN92
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS02360
gene id: 869210:MARKY_RS02360
uniprot id: F2NLV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS04950
gene id: 869210:MARKY_RS04950
uniprot id: F2NLB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

869210:MARKY RS03035
gene id: 869210:MARKY_RS03035
uniprot id: F2NQ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

869210:MARKY RS08390
gene id: 869210:MARKY_RS08390
uniprot id: F2NKF4
names: Subcellular Location Annotation
messages: Cytoplasm

869210:MARKY RS11315
gene id: 869210:MARKY_RS11315
uniprot id: F2NRC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

869210:MARKY RS05440
gene id: 869210:MARKY_RS05440
uniprot id: F2NME1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

869210:MARKY RS05980
gene id: 869210:MARKY_RS05980
uniprot id: F2NQJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

869210:MARKY RS00005
gene id: 869210:MARKY_RS00005
uniprot id: F2NNF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

869210:MARKY RS03365
gene id: 869210:MARKY_RS03365
uniprot id: F2NQ99
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS00020
gene id: 869210:MARKY_RS00020
uniprot id: F2NNF9
names: Similarity
messages: Belongs to the pyruvate kinase family.

869210:MARKY RS08060
gene id: 869210:MARKY_RS08060
uniprot id: F2NK88
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

869210:MARKY RS07425
gene id: 869210:MARKY_RS07425
uniprot id: F2NPD1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

869210:MARKY RS07985
gene id: 869210:MARKY_RS07985
uniprot id: F2NQV5
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS07655
gene id: 869210:MARKY_RS07655
uniprot id: F2NPH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

869210:MARKY RS01945
gene id: 869210:MARKY_RS01945
uniprot id: F2NKU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

869210:MARKY RS07815
gene id: 869210:MARKY_RS07815
uniprot id: F2NQS2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

869210:MARKY RS01760
gene id: 869210:MARKY_RS01760
uniprot id: F2NPZ9
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS03165
gene id: 869210:MARKY_RS03165
uniprot id: F2NQ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

869210:MARKY RS04175
gene id: 869210:MARKY_RS04175
uniprot id: F2NNY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

869210:MARKY RS07400
gene id: 869210:MARKY_RS07400
uniprot id: F2NPC6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

869210:MARKY RS10495
gene id: 869210:MARKY_RS10495
uniprot id: F2NN71
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

869210:MARKY RS06745
gene id: 869210:MARKY_RS06745
uniprot id: F2NLI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

869210:MARKY RS00880
gene id: 869210:MARKY_RS00880
uniprot id: F2NN91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS03300
gene id: 869210:MARKY_RS03300
uniprot id: F2NQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

869210:MARKY RS03350
gene id: 869210:MARKY_RS03350
uniprot id: F2NQ96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS02305
gene id: 869210:MARKY_RS02305
uniprot id: F2NL10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

869210:MARKY RS06985
gene id: 869210:MARKY_RS06985
uniprot id: F2NLM6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

869210:MARKY RS03595
gene id: 869210:MARKY_RS03595
uniprot id: F2NL54
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

869210:MARKY RS08675
gene id: 869210:MARKY_RS08675
uniprot id: F2NMS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

869210:MARKY RS00010
gene id: 869210:MARKY_RS00010
uniprot id: F2NNF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

869210:MARKY RS05240
gene id: 869210:MARKY_RS05240
uniprot id: F2NMA1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

869210:MARKY RS00040
gene id: 869210:MARKY_RS00040
uniprot id: F2NNG2
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS07745
gene id: 869210:MARKY_RS07745
uniprot id: F2NQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

869210:MARKY RS02345
gene id: 869210:MARKY_RS02345
uniprot id: F2NLV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

869210:MARKY RS00485
gene id: 869210:MARKY_RS00485
uniprot id: F2NKU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

869210:MARKY RS09140
gene id: 869210:MARKY_RS09140
uniprot id: F2NPP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

869210:MARKY RS03990
gene id: 869210:MARKY_RS03990
uniprot id: F2NM66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

869210:MARKY RS00305
gene id: 869210:MARKY_RS00305
uniprot id: F2NKQ5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

869210:MARKY RS10845
gene id: 869210:MARKY_RS10845
uniprot id: F2NPV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

869210:MARKY RS05140
gene id: 869210:MARKY_RS05140
uniprot id: F2NLE9
names: Subcellular Location Annotation
messages: Nucleus

869210:MARKY RS03945
gene id: 869210:MARKY_RS03945
uniprot id: F2NM57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

869210:MARKY RS04430
gene id: 869210:MARKY_RS04430
uniprot id: F2NP36
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

869210:MARKY RS08540
gene id: 869210:MARKY_RS08540
uniprot id: F2NMP9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

869210:MARKY RS03955
gene id: 869210:MARKY_RS03955
uniprot id: F2NM59
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

869210:MARKY RS00460
gene id: 869210:MARKY_RS00460
uniprot id: F2NKT7
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

869210:MARKY RS04640
gene id: 869210:MARKY_RS04640
uniprot id: F2NQE1
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

869210:MARKY RS03420
gene id: 869210:MARKY_RS03420
uniprot id: F2NL18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

869210:MARKY RS04150
gene id: 869210:MARKY_RS04150
uniprot id: F2NNX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

869210:MARKY RS06575
gene id: 869210:MARKY_RS06575
uniprot id: F2NK79
names: Similarity
messages: Belongs to the phosphohexose mutase family.

869210:MARKY RS03565
gene id: 869210:MARKY_RS03565
uniprot id: F2NL47
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

869210:MARKY RS10545
gene id: 869210:MARKY_RS10545
uniprot id: F2NN81
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS05120
gene id: 869210:MARKY_RS05120
uniprot id: F2NLE6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

869210:MARKY RS10350
gene id: 869210:MARKY_RS10350
uniprot id: F2NN43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

869210:MARKY RS05655
gene id: 869210:MARKY_RS05655
uniprot id: F2NP71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

869210:MARKY RS02270
gene id: 869210:MARKY_RS02270
uniprot id: F2NL03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

869210:MARKY RS07060
gene id: 869210:MARKY_RS07060
uniprot id: F2NMH0
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

869210:MARKY RS09260
gene id: 869210:MARKY_RS09260
uniprot id: F2NQZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

869210:MARKY RS05710
gene id: 869210:MARKY_RS05710
uniprot id: F2NP82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

869210:MARKY RS01670
gene id: 869210:MARKY_RS01670
uniprot id: F2NPY1
names: Similarity
messages: Belongs to the peptidase S49 family.

869210:MARKY RS01640
gene id: 869210:MARKY_RS01640
uniprot id: F2NPX5
names: Similarity
messages: Belongs to the universal stress protein A family.

869210:MARKY RS04560
gene id: 869210:MARKY_RS04560
uniprot id: F2NQC4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

869210:MARKY RS01385
gene id: 869210:MARKY_RS01385
uniprot id: F2NNL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

869210:MARKY RS09165
gene id: 869210:MARKY_RS09165
uniprot id: F2NQX4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

869210:MARKY RS05570
gene id: 869210:MARKY_RS05570
uniprot id: F2NP54
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS09835
gene id: 869210:MARKY_RS09835
uniprot id: F2NMV0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

869210:MARKY RS10690
gene id: 869210:MARKY_RS10690
uniprot id: F2NPS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

869210:MARKY RS05900
gene id: 869210:MARKY_RS05900
uniprot id: F2NQI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

869210:MARKY RS05965
gene id: 869210:MARKY_RS05965
uniprot id: F2NQJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

869210:MARKY RS10070
gene id: 869210:MARKY_RS10070
uniprot id: F2NMZ2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

869210:MARKY RS03900
gene id: 869210:MARKY_RS03900
uniprot id: F2NM48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

869210:MARKY RS11120
gene id: 869210:MARKY_RS11120
uniprot id: F2NR82
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

869210:MARKY RS01430
gene id: 869210:MARKY_RS01430
uniprot id: F2NNM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

869210:MARKY RS01840
gene id: 869210:MARKY_RS01840
uniprot id: F2NQ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

869210:MARKY RS01585
gene id: 869210:MARKY_RS01585
uniprot id: F2NPW5
names: Similarity
messages: Belongs to the P(II) protein family.

869210:MARKY RS02060
gene id: 869210:MARKY_RS02060
uniprot id: F2NKW8
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS05040
gene id: 869210:MARKY_RS05040
uniprot id: F2NLD0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

869210:MARKY RS06690
gene id: 869210:MARKY_RS06690
uniprot id: F2NLH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

869210:MARKY RS09965
gene id: 869210:MARKY_RS09965
uniprot id: F2NMX3
names: Subcellular Location Annotation
messages: Cytoplasm

869210:MARKY RS08805
gene id: 869210:MARKY_RS08805
uniprot id: F2NPI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

869210:MARKY RS07200
gene id: 869210:MARKY_RS07200
uniprot id: F2NMJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

869210:MARKY RS10415
gene id: 869210:MARKY_RS10415
uniprot id: F2NN55
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

869210:MARKY RS10380
gene id: 869210:MARKY_RS10380
uniprot id: F2NN49
names: Similarity
messages: Belongs to the leucine-binding protein family.

869210:MARKY RS00445
gene id: 869210:MARKY_RS00445
uniprot id: F2NKT4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

869210:MARKY RS05780
gene id: 869210:MARKY_RS05780
uniprot id: F2NP95
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

869210:MARKY RS01510
gene id: 869210:MARKY_RS01510
uniprot id: F2NNN7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

869210:MARKY RS09370
gene id: 869210:MARKY_RS09370
uniprot id: F2NR19
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

869210:MARKY RS02430
gene id: 869210:MARKY_RS02430
uniprot id: F2NLW9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

869210:MARKY RS07510
gene id: 869210:MARKY_RS07510
uniprot id: F2NPE8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

869210:MARKY RS09780
gene id: 869210:MARKY_RS09780
uniprot id: F2NKL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

869210:MARKY RS10460
gene id: 869210:MARKY_RS10460
uniprot id: F2NN64
names: Subcellular Location Annotation
messages: Membrane

869210:MARKY RS01790
gene id: 869210:MARKY_RS01790
uniprot id: F2NQ03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

869210:MARKY RS01490
gene id: 869210:MARKY_RS01490
uniprot id: F2NNN3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

869210:MARKY RS08260
gene id: 869210:MARKY_RS08260
uniprot id: F2NKC8
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.