866895:HBHAL RS20090
gene id: 866895:HBHAL_RS20090
uniprot id: I0JTL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ParB family.
messages: Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
messages: nucleoid

866895:HBHAL RS08905
gene id: 866895:HBHAL_RS08905
uniprot id: I0JLY8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

866895:HBHAL RS00600
gene id: 866895:HBHAL_RS00600
uniprot id: I0JH65
names: Similarity
messages: Belongs to the ClpA/ClpB family.

866895:HBHAL RS13040
gene id: 866895:HBHAL_RS13040
uniprot id: I0JPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

866895:HBHAL RS12690
gene id: 866895:HBHAL_RS12690
uniprot id: I0JP75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

866895:HBHAL RS00170
gene id: 866895:HBHAL_RS00170
uniprot id: I0JGZ9
names: Similarity
messages: Belongs to the peptidase C56 family.

866895:HBHAL RS12035
gene id: 866895:HBHAL_RS12035
uniprot id: I0JNU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

866895:HBHAL RS13510
gene id: 866895:HBHAL_RS13510
uniprot id: I0JPN7
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

866895:HBHAL RS18445
gene id: 866895:HBHAL_RS18445
uniprot id: I0JSM8
names: Similarity
messages: Belongs to the PspA/IM30 family.

866895:HBHAL RS17475
gene id: 866895:HBHAL_RS17475
uniprot id: I0JS28
names: Similarity
messages: Belongs to the LacAB/RpiB family.

866895:HBHAL RS07010
gene id: 866895:HBHAL_RS07010
uniprot id: I0JKU1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

866895:HBHAL RS15770
gene id: 866895:HBHAL_RS15770
uniprot id: I0JR03
names: Similarity
messages: Belongs to the CapA family.

866895:HBHAL RS14645
gene id: 866895:HBHAL_RS14645
uniprot id: I0JQC1
names: Similarity
messages: Belongs to the nitroreductase family.

866895:HBHAL RS04030
gene id: 866895:HBHAL_RS04030
uniprot id: I0JJ52
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

866895:HBHAL RS06065
gene id: 866895:HBHAL_RS06065
uniprot id: I0JK91
names: Similarity
messages: Belongs to the ABC transporter superfamily.

866895:HBHAL RS08580
gene id: 866895:HBHAL_RS08580
uniprot id: I0JLR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

866895:HBHAL RS05445
gene id: 866895:HBHAL_RS05445
uniprot id: I0JJX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

866895:HBHAL RS15390
gene id: 866895:HBHAL_RS15390
uniprot id: I0JQS1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

866895:HBHAL RS00475
gene id: 866895:HBHAL_RS00475
uniprot id: I0JH55
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

866895:HBHAL RS09150
gene id: 866895:HBHAL_RS09150
uniprot id: I0JM42
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

866895:HBHAL RS01555
gene id: 866895:HBHAL_RS01555
uniprot id: I0JHP8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS01235
gene id: 866895:HBHAL_RS01235
uniprot id: I0JHH8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

866895:HBHAL RS10375
gene id: 866895:HBHAL_RS10375
uniprot id: I0JMU7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

866895:HBHAL RS09325
gene id: 866895:HBHAL_RS09325
uniprot id: I0JM79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

866895:HBHAL RS13350
gene id: 866895:HBHAL_RS13350
uniprot id: I0JPK3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

866895:HBHAL RS16060
gene id: 866895:HBHAL_RS16060
uniprot id: I0JR64
names: Similarity
messages: Belongs to the EamA transporter family.

866895:HBHAL RS01865
gene id: 866895:HBHAL_RS01865
uniprot id: I0JHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09015
gene id: 866895:HBHAL_RS09015
uniprot id: I0JM13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

866895:HBHAL RS05890
gene id: 866895:HBHAL_RS05890
uniprot id: I0JK57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

866895:HBHAL RS09865
gene id: 866895:HBHAL_RS09865
uniprot id: I0JMJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

866895:HBHAL RS09860
gene id: 866895:HBHAL_RS09860
uniprot id: I0JMJ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

866895:HBHAL RS10255
gene id: 866895:HBHAL_RS10255
uniprot id: I0JMS2
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

866895:HBHAL RS20165
gene id: 866895:HBHAL_RS20165
uniprot id: I0JTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

866895:HBHAL RS14625
gene id: 866895:HBHAL_RS14625
uniprot id: I0JQB7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

866895:HBHAL RS10670
gene id: 866895:HBHAL_RS10670
uniprot id: I0JN09
names: Similarity
messages: Belongs to the CvfB family.

866895:HBHAL RS15310
gene id: 866895:HBHAL_RS15310
uniprot id: I0JQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

866895:HBHAL RS11375
gene id: 866895:HBHAL_RS11375
uniprot id: I0JNF6
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS17180
gene id: 866895:HBHAL_RS17180
uniprot id: I0JRW8
names: Similarity
messages: Belongs to the EamA transporter family.

866895:HBHAL RS10100
gene id: 866895:HBHAL_RS10100
uniprot id: I0JMP1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

866895:HBHAL RS02000
gene id: 866895:HBHAL_RS02000
uniprot id: I0JHZ2
names: Similarity
messages: Belongs to the EamA transporter family.

866895:HBHAL RS10050
gene id: 866895:HBHAL_RS10050
uniprot id: I0JMM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

866895:HBHAL RS01025
gene id: 866895:HBHAL_RS01025
uniprot id: I0JHD7
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

866895:HBHAL RS00605
gene id: 866895:HBHAL_RS00605
uniprot id: I0JH66
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

866895:HBHAL RS13405
gene id: 866895:HBHAL_RS13405
uniprot id: I0JPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

866895:HBHAL RS01040
gene id: 866895:HBHAL_RS01040
uniprot id: I0JHE1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

866895:HBHAL RS01915
gene id: 866895:HBHAL_RS01915
uniprot id: I0JHX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

866895:HBHAL RS20055
gene id: 866895:HBHAL_RS20055
uniprot id: I0JTK8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

866895:HBHAL RS00285
gene id: 866895:HBHAL_RS00285
uniprot id: I0JH18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

866895:HBHAL RS19705
gene id: 866895:HBHAL_RS19705
uniprot id: I0JTD9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

866895:HBHAL RS13050
gene id: 866895:HBHAL_RS13050
uniprot id: I0JPE7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

866895:HBHAL RS14600
gene id: 866895:HBHAL_RS14600
uniprot id: I0JQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

866895:HBHAL RS01610
gene id: 866895:HBHAL_RS01610
uniprot id: I0JHR4
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

866895:HBHAL RS16260
gene id: 866895:HBHAL_RS16260
uniprot id: I0JRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

866895:HBHAL RS05000
gene id: 866895:HBHAL_RS05000
uniprot id: I0JJQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

866895:HBHAL RS00755
gene id: 866895:HBHAL_RS00755
uniprot id: I0JH97
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

866895:HBHAL RS00720
gene id: 866895:HBHAL_RS00720
uniprot id: I0JH90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

866895:HBHAL RS11810
gene id: 866895:HBHAL_RS11810
uniprot id: I0JNP7
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS02640
gene id: 866895:HBHAL_RS02640
uniprot id: I0JIA7
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

866895:HBHAL RS01225
gene id: 866895:HBHAL_RS01225
uniprot id: I0JHH6
names: Function
names: Similarity
messages: Belongs to the uve1/UvsE family.
messages: Component in a DNA repair pathway. Removal of UV LIGHT damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion.
messages: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion.

866895:HBHAL RS19540
gene id: 866895:HBHAL_RS19540
uniprot id: I0JTA3
names: Similarity
messages: Belongs to the MQO family.

866895:HBHAL RS00740
gene id: 866895:HBHAL_RS00740
uniprot id: I0JH94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

866895:HBHAL RS13230
gene id: 866895:HBHAL_RS13230
uniprot id: I0JPH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

866895:HBHAL RS10845
gene id: 866895:HBHAL_RS10845
uniprot id: I0JN45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

866895:HBHAL RS16715
gene id: 866895:HBHAL_RS16715
uniprot id: I0JRL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

866895:HBHAL RS20175
gene id: 866895:HBHAL_RS20175
uniprot id: I0JTN3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS04995
gene id: 866895:HBHAL_RS04995
uniprot id: I0JJQ1
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

866895:HBHAL RS04180
gene id: 866895:HBHAL_RS04180
uniprot id: I0JJ83
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS00790
gene id: 866895:HBHAL_RS00790
uniprot id: I0JHA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

866895:HBHAL RS05090
gene id: 866895:HBHAL_RS05090
uniprot id: I0JJR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS06825
gene id: 866895:HBHAL_RS06825
uniprot id: I0JKQ5
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

866895:HBHAL RS17385
gene id: 866895:HBHAL_RS17385
uniprot id: I0JS09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS00750
gene id: 866895:HBHAL_RS00750
uniprot id: I0JH96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

866895:HBHAL RS04735
gene id: 866895:HBHAL_RS04735
uniprot id: I0JJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS15325
gene id: 866895:HBHAL_RS15325
uniprot id: I0JQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

866895:HBHAL RS19030
gene id: 866895:HBHAL_RS19030
uniprot id: I0JT01
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS07790
gene id: 866895:HBHAL_RS07790
uniprot id: I0JL95
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS07765
gene id: 866895:HBHAL_RS07765
uniprot id: I0JQV5
names: Similarity
messages: Belongs to the transposase 11 family.

866895:HBHAL RS08665
gene id: 866895:HBHAL_RS08665
uniprot id: I0JLT6
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11555
gene id: 866895:HBHAL_RS11555
uniprot id: I0JNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS13955
gene id: 866895:HBHAL_RS13955
uniprot id: I0JPX9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

866895:HBHAL RS15295
gene id: 866895:HBHAL_RS15295
uniprot id: I0JQQ2
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

866895:HBHAL RS10265
gene id: 866895:HBHAL_RS10265
uniprot id: I0JMS4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

866895:HBHAL RS05545
gene id: 866895:HBHAL_RS05545
uniprot id: I0JJZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

866895:HBHAL RS13875
gene id: 866895:HBHAL_RS13875
uniprot id: I0JPW2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

866895:HBHAL RS00460
gene id: 866895:HBHAL_RS00460
uniprot id: I0JH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

866895:HBHAL RS00595
gene id: 866895:HBHAL_RS00595
uniprot id: I0JH64
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.

866895:HBHAL RS12045
gene id: 866895:HBHAL_RS12045
uniprot id: I0JNU8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

866895:HBHAL RS01050
gene id: 866895:HBHAL_RS01050
uniprot id: I0JHE3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

866895:HBHAL RS10190
gene id: 866895:HBHAL_RS10190
uniprot id: I0JMQ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

866895:HBHAL RS16560
gene id: 866895:HBHAL_RS16560
uniprot id: I0JRH8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS19510
gene id: 866895:HBHAL_RS19510
uniprot id: I0JT97
names: Similarity
messages: Belongs to the peptidase C40 family.

866895:HBHAL RS00375
gene id: 866895:HBHAL_RS00375
uniprot id: I0JH36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

866895:HBHAL RS10570
gene id: 866895:HBHAL_RS10570
uniprot id: I0JMY8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS13135
gene id: 866895:HBHAL_RS13135
uniprot id: I0JPG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

866895:HBHAL RS19590
gene id: 866895:HBHAL_RS19590
uniprot id: I0JTB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

866895:HBHAL RS04245
gene id: 866895:HBHAL_RS04245
uniprot id: I0JJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS00745
gene id: 866895:HBHAL_RS00745
uniprot id: I0JH95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

866895:HBHAL RS15010
gene id: 866895:HBHAL_RS15010
uniprot id: I0JQJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

866895:HBHAL RS05610
gene id: 866895:HBHAL_RS05610
uniprot id: I0JK02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS11100
gene id: 866895:HBHAL_RS11100
uniprot id: I0JNA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

866895:HBHAL RS12925
gene id: 866895:HBHAL_RS12925
uniprot id: I0JPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

866895:HBHAL RS00895
gene id: 866895:HBHAL_RS00895
uniprot id: I0JHC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

866895:HBHAL RS13330
gene id: 866895:HBHAL_RS13330
uniprot id: I0JPJ8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

866895:HBHAL RS00025
gene id: 866895:HBHAL_RS00025
uniprot id: I0JGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

866895:HBHAL RS02500
gene id: 866895:HBHAL_RS02500
uniprot id: I0JI76
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS13975
gene id: 866895:HBHAL_RS13975
uniprot id: I0JPY3
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

866895:HBHAL RS05950
gene id: 866895:HBHAL_RS05950
uniprot id: Q00213
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.
messages: SASP are degraded in the first minutes of spore germination and provide amino acids for both new protein synthesis and metabolism.

866895:HBHAL RS09330
gene id: 866895:HBHAL_RS09330
uniprot id: I0JM80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

866895:HBHAL RS06800
gene id: 866895:HBHAL_RS06800
uniprot id: I0JKQ0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

866895:HBHAL RS03610
gene id: 866895:HBHAL_RS03610
uniprot id: I0JIW3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS12390
gene id: 866895:HBHAL_RS12390
uniprot id: I0JP12
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS08730
gene id: 866895:HBHAL_RS08730
uniprot id: I0JLV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS03505
gene id: 866895:HBHAL_RS03505
uniprot id: I0JIU1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

866895:HBHAL RS07855
gene id: 866895:HBHAL_RS07855
uniprot id: I0JLB0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS19945
gene id: 866895:HBHAL_RS19945
uniprot id: I0JTI7
names: Similarity
messages: Belongs to the LOG family.

866895:HBHAL RS00610
gene id: 866895:HBHAL_RS00610
uniprot id: I0JH67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

866895:HBHAL RS03025
gene id: 866895:HBHAL_RS03025
uniprot id: I0JII7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS05165
gene id: 866895:HBHAL_RS05165
uniprot id: I0JJT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

866895:HBHAL RS04260
gene id: 866895:HBHAL_RS04260
uniprot id: I0JJA0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS07285
gene id: 866895:HBHAL_RS07285
uniprot id: I0JL01
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

866895:HBHAL RS09110
gene id: 866895:HBHAL_RS09110
uniprot id: I0JM33
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS06335
gene id: 866895:HBHAL_RS06335
uniprot id: I0JKE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

866895:HBHAL RS00580
gene id: 866895:HBHAL_RS00580
uniprot id: I0JH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

866895:HBHAL RS09030
gene id: 866895:HBHAL_RS09030
uniprot id: I0JM16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

866895:HBHAL RS20445
gene id: 866895:HBHAL_RS20445
uniprot id: I0JQX9
names: Similarity
messages: Belongs to the peptidase C40 family.

866895:HBHAL RS10560
gene id: 866895:HBHAL_RS10560
uniprot id: I0JMY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

866895:HBHAL RS04020
gene id: 866895:HBHAL_RS04020
uniprot id: I0JJ50
names: Similarity
messages: Belongs to the ComB family.

866895:HBHAL RS13410
gene id: 866895:HBHAL_RS13410
uniprot id: I0JPL6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS20100
gene id: 866895:HBHAL_RS20100
uniprot id: I0JTL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS02775
gene id: 866895:HBHAL_RS02775
uniprot id: I0JID7
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS09520
gene id: 866895:HBHAL_RS09520
uniprot id: I0JMB9
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

866895:HBHAL RS12870
gene id: 866895:HBHAL_RS12870
uniprot id: I0JPB1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS10715
gene id: 866895:HBHAL_RS10715
uniprot id: I0JN19
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

866895:HBHAL RS01360
gene id: 866895:HBHAL_RS01360
uniprot id: I0JHK2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

866895:HBHAL RS18990
gene id: 866895:HBHAL_RS18990
uniprot id: I0JSZ3
names: Similarity
messages: Belongs to the CdaR family.

866895:HBHAL RS05205
gene id: 866895:HBHAL_RS05205
uniprot id: I0JJU1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS01510
gene id: 866895:HBHAL_RS01510
uniprot id: I0JHP1
names: Subcellular Location Annotation
messages: Cell membrane

866895:HBHAL RS01085
gene id: 866895:HBHAL_RS01085
uniprot id: I0JHE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

866895:HBHAL RS10055
gene id: 866895:HBHAL_RS10055
uniprot id: I0JMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

866895:HBHAL RS14720
gene id: 866895:HBHAL_RS14720
uniprot id: I0JQD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

866895:HBHAL RS01285
gene id: 866895:HBHAL_RS01285
uniprot id: I0JHI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

866895:HBHAL RS18525
gene id: 866895:HBHAL_RS18525
uniprot id: I0JSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

866895:HBHAL RS03870
gene id: 866895:HBHAL_RS03870
uniprot id: I0JJ19
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS14660
gene id: 866895:HBHAL_RS14660
uniprot id: I0JQC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

866895:HBHAL RS12685
gene id: 866895:HBHAL_RS12685
uniprot id: I0JP74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

866895:HBHAL RS16420
gene id: 866895:HBHAL_RS16420
uniprot id: I0JRE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS16895
gene id: 866895:HBHAL_RS16895
uniprot id: I0JRQ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS16630
gene id: 866895:HBHAL_RS16630
uniprot id: I0JRJ2
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS08475
gene id: 866895:HBHAL_RS08475
uniprot id: I0JLP4
names: Subcellular Location Annotation
messages: Cell membrane

866895:HBHAL RS12250
gene id: 866895:HBHAL_RS12250
uniprot id: I0JNY8
names: Similarity
messages: Belongs to the ArsC family.

866895:HBHAL RS01530
gene id: 866895:HBHAL_RS01530
uniprot id: I0JHP5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS06490
gene id: 866895:HBHAL_RS06490
uniprot id: I0JKI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS11030
gene id: 866895:HBHAL_RS11030
uniprot id: I0JN86
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

866895:HBHAL RS13495
gene id: 866895:HBHAL_RS13495
uniprot id: I0JPN4
names: Similarity
messages: Belongs to the citrate synthase family.

866895:HBHAL RS08170
gene id: 866895:HBHAL_RS08170
uniprot id: I0JLH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

866895:HBHAL RS04190
gene id: 866895:HBHAL_RS04190
uniprot id: I0JJ85
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

866895:HBHAL RS09195
gene id: 866895:HBHAL_RS09195
uniprot id: I0JM51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

866895:HBHAL RS05975
gene id: 866895:HBHAL_RS05975
uniprot id: I0JK75
names: Similarity
messages: Belongs to the UPF0754 family.

866895:HBHAL RS18075
gene id: 866895:HBHAL_RS18075
uniprot id: I0JSE8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

866895:HBHAL RS19520
gene id: 866895:HBHAL_RS19520
uniprot id: I0JT99
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS00855
gene id: 866895:HBHAL_RS00855
uniprot id: I0JHB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

866895:HBHAL RS04470
gene id: 866895:HBHAL_RS04470
uniprot id: I0JJE5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS06230
gene id: 866895:HBHAL_RS06230
uniprot id: I0JKC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

866895:HBHAL RS19845
gene id: 866895:HBHAL_RS19845
uniprot id: I0JTG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

866895:HBHAL RS15285
gene id: 866895:HBHAL_RS15285
uniprot id: I0JQQ0
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

866895:HBHAL RS16695
gene id: 866895:HBHAL_RS16695
uniprot id: I0JRK5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11140
gene id: 866895:HBHAL_RS11140
uniprot id: I0JNA8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

866895:HBHAL RS12530
gene id: 866895:HBHAL_RS12530
uniprot id: I0JP42
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12495
gene id: 866895:HBHAL_RS12495
uniprot id: I0JP35
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

866895:HBHAL RS01310
gene id: 866895:HBHAL_RS01310
uniprot id: I0JHJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

866895:HBHAL RS10235
gene id: 866895:HBHAL_RS10235
uniprot id: I0JMR7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

866895:HBHAL RS01245
gene id: 866895:HBHAL_RS01245
uniprot id: I0JHI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09790
gene id: 866895:HBHAL_RS09790
uniprot id: I0JMH6
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

866895:HBHAL RS10325
gene id: 866895:HBHAL_RS10325
uniprot id: I0JMT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

866895:HBHAL RS10060
gene id: 866895:HBHAL_RS10060
uniprot id: I0JMN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

866895:HBHAL RS03560
gene id: 866895:HBHAL_RS03560
uniprot id: I0JIV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS13395
gene id: 866895:HBHAL_RS13395
uniprot id: I0JPL3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

866895:HBHAL RS13300
gene id: 866895:HBHAL_RS13300
uniprot id: I0JPJ2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

866895:HBHAL RS18575
gene id: 866895:HBHAL_RS18575
uniprot id: I0JSQ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS01630
gene id: 866895:HBHAL_RS01630
uniprot id: I0JHR8
names: Function
names: Similarity
messages: Functions as a fatty acid monooxygenase.
messages: In the N-terminal section; belongs to the cytochrome P450 family.

866895:HBHAL RS02825
gene id: 866895:HBHAL_RS02825
uniprot id: I0JIE7
names: Similarity
messages: Belongs to the thioesterase PaaI family.

866895:HBHAL RS09915
gene id: 866895:HBHAL_RS09915
uniprot id: I0JMK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

866895:HBHAL RS14580
gene id: 866895:HBHAL_RS14580
uniprot id: I0JQA8
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

866895:HBHAL RS04535
gene id: 866895:HBHAL_RS04535
uniprot id: I0JJF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

866895:HBHAL RS14735
gene id: 866895:HBHAL_RS14735
uniprot id: I0JQD8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

866895:HBHAL RS00195
gene id: 866895:HBHAL_RS00195
uniprot id: I0JH04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

866895:HBHAL RS02040
gene id: 866895:HBHAL_RS02040
uniprot id: I0JI00
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

866895:HBHAL RS05980
gene id: 866895:HBHAL_RS05980
uniprot id: I0JK76
names: Similarity
messages: Belongs to the UPF0342 family.

866895:HBHAL RS00360
gene id: 866895:HBHAL_RS00360
uniprot id: I0JH33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

866895:HBHAL RS03065
gene id: 866895:HBHAL_RS03065
uniprot id: I0JIJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

866895:HBHAL RS07640
gene id: 866895:HBHAL_RS07640
uniprot id: I0JL64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

866895:HBHAL RS00710
gene id: 866895:HBHAL_RS00710
uniprot id: I0JH88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

866895:HBHAL RS09000
gene id: 866895:HBHAL_RS09000
uniprot id: I0JM09
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS14365
gene id: 866895:HBHAL_RS14365
uniprot id: I0JQ66
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

866895:HBHAL RS02685
gene id: 866895:HBHAL_RS02685
uniprot id: I0JIB6
names: Similarity
messages: Belongs to the transpeptidase family.

866895:HBHAL RS19970
gene id: 866895:HBHAL_RS19970
uniprot id: I0JTJ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

866895:HBHAL RS04265
gene id: 866895:HBHAL_RS04265
uniprot id: I0JJA1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

866895:HBHAL RS14745
gene id: 866895:HBHAL_RS14745
uniprot id: I0JQE0
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

866895:HBHAL RS13475
gene id: 866895:HBHAL_RS13475
uniprot id: I0JPN0
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS19685
gene id: 866895:HBHAL_RS19685
uniprot id: I0JTD5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

866895:HBHAL RS01750
gene id: 866895:HBHAL_RS01750
uniprot id: I0JHU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

866895:HBHAL RS00095
gene id: 866895:HBHAL_RS00095
uniprot id: I0JGY5
names: Similarity
messages: Belongs to the DCK/DGK family.

866895:HBHAL RS14305
gene id: 866895:HBHAL_RS14305
uniprot id: I0JQ53
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

866895:HBHAL RS10835
gene id: 866895:HBHAL_RS10835
uniprot id: I0JN43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

866895:HBHAL RS19820
gene id: 866895:HBHAL_RS19820
uniprot id: I0JTG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

866895:HBHAL RS01550
gene id: 866895:HBHAL_RS01550
uniprot id: I0JHP7
names: Similarity
messages: Belongs to the peptidase C56 family.

866895:HBHAL RS11490
gene id: 866895:HBHAL_RS11490
uniprot id: I0JNI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

866895:HBHAL RS03020
gene id: 866895:HBHAL_RS03020
uniprot id: I0JII6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

866895:HBHAL RS12740
gene id: 866895:HBHAL_RS12740
uniprot id: I0JP85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

866895:HBHAL RS13465
gene id: 866895:HBHAL_RS13465
uniprot id: I0JPM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

866895:HBHAL RS08135
gene id: 866895:HBHAL_RS08135
uniprot id: I0JLH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family. IolA subfamily.
messages: Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
messages: Homotetramer.

866895:HBHAL RS11960
gene id: 866895:HBHAL_RS11960
uniprot id: I0JNT1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

866895:HBHAL RS16825
gene id: 866895:HBHAL_RS16825
uniprot id: I0JRN7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

866895:HBHAL RS00685
gene id: 866895:HBHAL_RS00685
uniprot id: I0JH83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

866895:HBHAL RS09780
gene id: 866895:HBHAL_RS09780
uniprot id: I0JMH4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

866895:HBHAL RS17675
gene id: 866895:HBHAL_RS17675
uniprot id: I0JS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS11890
gene id: 866895:HBHAL_RS11890
uniprot id: I0JNR4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS17700
gene id: 866895:HBHAL_RS17700
uniprot id: I0JS76
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

866895:HBHAL RS17105
gene id: 866895:HBHAL_RS17105
uniprot id: I0JRV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

866895:HBHAL RS00680
gene id: 866895:HBHAL_RS00680
uniprot id: I0JH82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

866895:HBHAL RS12855
gene id: 866895:HBHAL_RS12855
uniprot id: I0JPA8
names: Similarity
messages: Belongs to the RecJ family.

866895:HBHAL RS14530
gene id: 866895:HBHAL_RS14530
uniprot id: I0JQ98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS01120
gene id: 866895:HBHAL_RS01120
uniprot id: I0JHF6
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS15110
gene id: 866895:HBHAL_RS15110
uniprot id: I0JQL6
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS14460
gene id: 866895:HBHAL_RS14460
uniprot id: I0JQ83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS15235
gene id: 866895:HBHAL_RS15235
uniprot id: I0JQP0
names: Similarity
messages: Belongs to the CdaR family.

866895:HBHAL RS13000
gene id: 866895:HBHAL_RS13000
uniprot id: I0JPD7
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

866895:HBHAL RS05690
gene id: 866895:HBHAL_RS05690
uniprot id: I0JK18
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

866895:HBHAL RS18170
gene id: 866895:HBHAL_RS18170
uniprot id: I0JSG8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

866895:HBHAL RS13705
gene id: 866895:HBHAL_RS13705
uniprot id: I0JPS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS03510
gene id: 866895:HBHAL_RS03510
uniprot id: I0JIU2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

866895:HBHAL RS14845
gene id: 866895:HBHAL_RS14845
uniprot id: I0JQF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

866895:HBHAL RS17600
gene id: 866895:HBHAL_RS17600
uniprot id: I0JS56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS03635
gene id: 866895:HBHAL_RS03635
uniprot id: I0JIW8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

866895:HBHAL RS09920
gene id: 866895:HBHAL_RS09920
uniprot id: I0JMK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

866895:HBHAL RS06500
gene id: 866895:HBHAL_RS06500
uniprot id: I0JKI5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

866895:HBHAL RS12695
gene id: 866895:HBHAL_RS12695
uniprot id: I0JP76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS14715
gene id: 866895:HBHAL_RS14715
uniprot id: I0JQD4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

866895:HBHAL RS10350
gene id: 866895:HBHAL_RS10350
uniprot id: I0JMU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

866895:HBHAL RS12020
gene id: 866895:HBHAL_RS12020
uniprot id: I0JNU2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

866895:HBHAL RS15570
gene id: 866895:HBHAL_RS15570
uniprot id: I0JQW3
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS02970
gene id: 866895:HBHAL_RS02970
uniprot id: I0JIH6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

866895:HBHAL RS06770
gene id: 866895:HBHAL_RS06770
uniprot id: I0JKP4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS10040
gene id: 866895:HBHAL_RS10040
uniprot id: I0JMM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

866895:HBHAL RS08125
gene id: 866895:HBHAL_RS08125
uniprot id: I0JLH0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

866895:HBHAL RS09230
gene id: 866895:HBHAL_RS09230
uniprot id: I0JM58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
messages: Self-associates. Interacts with SigE. Interacts with SpoIIR.

866895:HBHAL RS00465
gene id: 866895:HBHAL_RS00465
uniprot id: I0JH53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

866895:HBHAL RS13095
gene id: 866895:HBHAL_RS13095
uniprot id: I0JPF6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

866895:HBHAL RS15460
gene id: 866895:HBHAL_RS15460
uniprot id: I0JQT7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

866895:HBHAL RS12485
gene id: 866895:HBHAL_RS12485
uniprot id: I0JP31
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

866895:HBHAL RS10985
gene id: 866895:HBHAL_RS10985
uniprot id: I0JN76
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS13400
gene id: 866895:HBHAL_RS13400
uniprot id: I0JPL4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

866895:HBHAL RS10320
gene id: 866895:HBHAL_RS10320
uniprot id: I0JMT6
names: Similarity
messages: Belongs to the CinA family.

866895:HBHAL RS10820
gene id: 866895:HBHAL_RS10820
uniprot id: I0JN40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

866895:HBHAL RS03100
gene id: 866895:HBHAL_RS03100
uniprot id: I0JIK2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

866895:HBHAL RS00120
gene id: 866895:HBHAL_RS00120
uniprot id: I0JGY9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

866895:HBHAL RS03010
gene id: 866895:HBHAL_RS03010
uniprot id: I0JII4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

866895:HBHAL RS18790
gene id: 866895:HBHAL_RS18790
uniprot id: I0JSV2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

866895:HBHAL RS02880
gene id: 866895:HBHAL_RS02880
uniprot id: I0JIF7
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS12330
gene id: 866895:HBHAL_RS12330
uniprot id: I0JP06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS14300
gene id: 866895:HBHAL_RS14300
uniprot id: I0JQ52
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

866895:HBHAL RS16955
gene id: 866895:HBHAL_RS16955
uniprot id: I0JRR9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

866895:HBHAL RS18285
gene id: 866895:HBHAL_RS18285
uniprot id: I0JSJ2
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS09440
gene id: 866895:HBHAL_RS09440
uniprot id: I0JMA2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS01785
gene id: 866895:HBHAL_RS01785
uniprot id: I0JHU9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

866895:HBHAL RS12055
gene id: 866895:HBHAL_RS12055
uniprot id: I0JNV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

866895:HBHAL RS00670
gene id: 866895:HBHAL_RS00670
uniprot id: I0JH80
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

866895:HBHAL RS14775
gene id: 866895:HBHAL_RS14775
uniprot id: I0JQE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

866895:HBHAL RS04370
gene id: 866895:HBHAL_RS04370
uniprot id: I0JJC4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11645
gene id: 866895:HBHAL_RS11645
uniprot id: I0JNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS17415
gene id: 866895:HBHAL_RS17415
uniprot id: I0JS15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

866895:HBHAL RS14360
gene id: 866895:HBHAL_RS14360
uniprot id: I0JQ65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS16605
gene id: 866895:HBHAL_RS16605
uniprot id: I0JRI7
names: Similarity
messages: Belongs to the acyltransferase 3 family.

866895:HBHAL RS05110
gene id: 866895:HBHAL_RS05110
uniprot id: I0JJS3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

866895:HBHAL RS17690
gene id: 866895:HBHAL_RS17690
uniprot id: I0JS74
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

866895:HBHAL RS03445
gene id: 866895:HBHAL_RS03445
uniprot id: I0JIS9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

866895:HBHAL RS15035
gene id: 866895:HBHAL_RS15035
uniprot id: I0JQK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

866895:HBHAL RS13325
gene id: 866895:HBHAL_RS13325
uniprot id: I0JPJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

866895:HBHAL RS09700
gene id: 866895:HBHAL_RS09700
uniprot id: I0JMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS19035
gene id: 866895:HBHAL_RS19035
uniprot id: I0JT02
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

866895:HBHAL RS10000
gene id: 866895:HBHAL_RS10000
uniprot id: I0JML8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

866895:HBHAL RS18975
gene id: 866895:HBHAL_RS18975
uniprot id: I0JSZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

866895:HBHAL RS09360
gene id: 866895:HBHAL_RS09360
uniprot id: I0JM86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

866895:HBHAL RS09800
gene id: 866895:HBHAL_RS09800
uniprot id: I0JMH8
names: Similarity
messages: Belongs to the fabD family.

866895:HBHAL RS05015
gene id: 866895:HBHAL_RS05015
uniprot id: I0JJQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

866895:HBHAL RS07830
gene id: 866895:HBHAL_RS07830
uniprot id: I0JLA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

866895:HBHAL RS12545
gene id: 866895:HBHAL_RS12545
uniprot id: I0JP45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

866895:HBHAL RS07020
gene id: 866895:HBHAL_RS07020
uniprot id: I0JKU3
names: Similarity
messages: Belongs to the TelA family.

866895:HBHAL RS17610
gene id: 866895:HBHAL_RS17610
uniprot id: I0JS58
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

866895:HBHAL RS05260
gene id: 866895:HBHAL_RS05260
uniprot id: I0JJV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS14265
gene id: 866895:HBHAL_RS14265
uniprot id: I0JQ45
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS13120
gene id: 866895:HBHAL_RS13120
uniprot id: I0JPG1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

866895:HBHAL RS12550
gene id: 866895:HBHAL_RS12550
uniprot id: I0JP46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

866895:HBHAL RS12310
gene id: 866895:HBHAL_RS12310
uniprot id: I0JP00
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

866895:HBHAL RS10745
gene id: 866895:HBHAL_RS10745
uniprot id: I0JN25
names: Similarity
messages: Belongs to the acylphosphatase family.

866895:HBHAL RS03085
gene id: 866895:HBHAL_RS03085
uniprot id: I0JIJ9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

866895:HBHAL RS17335
gene id: 866895:HBHAL_RS17335
uniprot id: I0JRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

866895:HBHAL RS15690
gene id: 866895:HBHAL_RS15690
uniprot id: I0JQY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS11125
gene id: 866895:HBHAL_RS11125
uniprot id: I0JNA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

866895:HBHAL RS14350
gene id: 866895:HBHAL_RS14350
uniprot id: I0JQ63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

866895:HBHAL RS08470
gene id: 866895:HBHAL_RS08470
uniprot id: I0JLP3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

866895:HBHAL RS13005
gene id: 866895:HBHAL_RS13005
uniprot id: I0JPD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

866895:HBHAL RS20555
gene id: 866895:HBHAL_RS20555
uniprot id: I0JJP9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

866895:HBHAL RS03015
gene id: 866895:HBHAL_RS03015
uniprot id: I0JII5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09120
gene id: 866895:HBHAL_RS09120
uniprot id: I0JM35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS10535
gene id: 866895:HBHAL_RS10535
uniprot id: I0JMY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

866895:HBHAL RS13805
gene id: 866895:HBHAL_RS13805
uniprot id: I0JPU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

866895:HBHAL RS09845
gene id: 866895:HBHAL_RS09845
uniprot id: I0JMI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

866895:HBHAL RS00795
gene id: 866895:HBHAL_RS00795
uniprot id: I0JHA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

866895:HBHAL RS10970
gene id: 866895:HBHAL_RS10970
uniprot id: I0JN73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

866895:HBHAL RS11410
gene id: 866895:HBHAL_RS11410
uniprot id: I0JNG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

866895:HBHAL RS00925
gene id: 866895:HBHAL_RS00925
uniprot id: I0JHD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

866895:HBHAL RS04745
gene id: 866895:HBHAL_RS04745
uniprot id: I0JJJ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

866895:HBHAL RS02250
gene id: 866895:HBHAL_RS02250
uniprot id: I0JI24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

866895:HBHAL RS05280
gene id: 866895:HBHAL_RS05280
uniprot id: I0JJV8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

866895:HBHAL RS11735
gene id: 866895:HBHAL_RS11735
uniprot id: I0JNN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

866895:HBHAL RS07780
gene id: 866895:HBHAL_RS07780
uniprot id: I0JL93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

866895:HBHAL RS14315
gene id: 866895:HBHAL_RS14315
uniprot id: I0JQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

866895:HBHAL RS16950
gene id: 866895:HBHAL_RS16950
uniprot id: I0JRR8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

866895:HBHAL RS18625
gene id: 866895:HBHAL_RS18625
uniprot id: I0JSR6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

866895:HBHAL RS05565
gene id: 866895:HBHAL_RS05565
uniprot id: I0JJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS20335
gene id: 866895:HBHAL_RS20335
uniprot id: I0JJM2
names: Similarity
messages: Belongs to the phosphoribulokinase family.

866895:HBHAL RS10485
gene id: 866895:HBHAL_RS10485
uniprot id: I0JMX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

866895:HBHAL RS15685
gene id: 866895:HBHAL_RS15685
uniprot id: I0JQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS18290
gene id: 866895:HBHAL_RS18290
uniprot id: I0JSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS16535
gene id: 866895:HBHAL_RS16535
uniprot id: I0JRH3
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS13920
gene id: 866895:HBHAL_RS13920
uniprot id: I0JPW9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS14755
gene id: 866895:HBHAL_RS14755
uniprot id: I0JQE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

866895:HBHAL RS01065
gene id: 866895:HBHAL_RS01065
uniprot id: I0JHE5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

866895:HBHAL RS18760
gene id: 866895:HBHAL_RS18760
uniprot id: I0JSU5
names: Similarity
messages: Belongs to the IucA/IucC family.

866895:HBHAL RS08415
gene id: 866895:HBHAL_RS08415
uniprot id: I0JLN2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS08325
gene id: 866895:HBHAL_RS08325
uniprot id: I0JLL2
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.

866895:HBHAL RS09785
gene id: 866895:HBHAL_RS09785
uniprot id: I0JMH5
names: Similarity
messages: Belongs to the peptidase S66 family.

866895:HBHAL RS00625
gene id: 866895:HBHAL_RS00625
uniprot id: I0JH70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

866895:HBHAL RS10085
gene id: 866895:HBHAL_RS10085
uniprot id: I0JMN6
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

866895:HBHAL RS15650
gene id: 866895:HBHAL_RS15650
uniprot id: I0JQX8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS12345
gene id: 866895:HBHAL_RS12345
uniprot id: I0JP09
names: Similarity
messages: Belongs to the transpeptidase family.

866895:HBHAL RS09770
gene id: 866895:HBHAL_RS09770
uniprot id: I0JMH2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

866895:HBHAL RS11005
gene id: 866895:HBHAL_RS11005
uniprot id: I0JN81
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

866895:HBHAL RS12635
gene id: 866895:HBHAL_RS12635
uniprot id: I0JP63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

866895:HBHAL RS14110
gene id: 866895:HBHAL_RS14110
uniprot id: I0JQ12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

866895:HBHAL RS10205
gene id: 866895:HBHAL_RS10205
uniprot id: I0JMR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

866895:HBHAL RS08845
gene id: 866895:HBHAL_RS08845
uniprot id: I0JLX6
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS13655
gene id: 866895:HBHAL_RS13655
uniprot id: I0JPR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

866895:HBHAL RS10200
gene id: 866895:HBHAL_RS10200
uniprot id: I0JMR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

866895:HBHAL RS04025
gene id: 866895:HBHAL_RS04025
uniprot id: I0JJ51
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS17550
gene id: 866895:HBHAL_RS17550
uniprot id: I0JS46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

866895:HBHAL RS20150
gene id: 866895:HBHAL_RS20150
uniprot id: I0JTM7
names: Similarity
messages: Belongs to the FPG family.

866895:HBHAL RS15055
gene id: 866895:HBHAL_RS15055
uniprot id: I0JQK5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

866895:HBHAL RS08545
gene id: 866895:HBHAL_RS08545
uniprot id: I0JLQ9
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

866895:HBHAL RS09255
gene id: 866895:HBHAL_RS09255
uniprot id: I0JM64
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

866895:HBHAL RS18230
gene id: 866895:HBHAL_RS18230
uniprot id: I0JSI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

866895:HBHAL RS19275
gene id: 866895:HBHAL_RS19275
uniprot id: I0JT51
names: Similarity
messages: Belongs to the sigma-54 factor family.

866895:HBHAL RS11790
gene id: 866895:HBHAL_RS11790
uniprot id: I0JNP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

866895:HBHAL RS12980
gene id: 866895:HBHAL_RS12980
uniprot id: I0JPD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

866895:HBHAL RS00585
gene id: 866895:HBHAL_RS00585
uniprot id: I0JH62
names: Similarity
messages: Belongs to the CtsR family.

866895:HBHAL RS05855
gene id: 866895:HBHAL_RS05855
uniprot id: I0JK50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

866895:HBHAL RS05245
gene id: 866895:HBHAL_RS05245
uniprot id: I0JJV0
names: Similarity
messages: Belongs to the UPF0374 family.

866895:HBHAL RS00840
gene id: 866895:HBHAL_RS00840
uniprot id: I0JHB4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

866895:HBHAL RS19465
gene id: 866895:HBHAL_RS19465
uniprot id: I0JT87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS07590
gene id: 866895:HBHAL_RS07590
uniprot id: I0JL56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS13625
gene id: 866895:HBHAL_RS13625
uniprot id: I0JPR1
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

866895:HBHAL RS12050
gene id: 866895:HBHAL_RS12050
uniprot id: I0JNU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

866895:HBHAL RS17695
gene id: 866895:HBHAL_RS17695
uniprot id: I0JS75
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

866895:HBHAL RS06910
gene id: 866895:HBHAL_RS06910
uniprot id: I0JKS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

866895:HBHAL RS03050
gene id: 866895:HBHAL_RS03050
uniprot id: I0JIJ2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

866895:HBHAL RS16925
gene id: 866895:HBHAL_RS16925
uniprot id: I0JRR3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

866895:HBHAL RS15025
gene id: 866895:HBHAL_RS15025
uniprot id: I0JQJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

866895:HBHAL RS06365
gene id: 866895:HBHAL_RS06365
uniprot id: I0JKF4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS08725
gene id: 866895:HBHAL_RS08725
uniprot id: I0JQV5
names: Similarity
messages: Belongs to the transposase 11 family.

866895:HBHAL RS15730
gene id: 866895:HBHAL_RS15730
uniprot id: I0JQZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

866895:HBHAL RS10960
gene id: 866895:HBHAL_RS10960
uniprot id: I0JN71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

866895:HBHAL RS01675
gene id: 866895:HBHAL_RS01675
uniprot id: I0JHS8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

866895:HBHAL RS08290
gene id: 866895:HBHAL_RS08290
uniprot id: I0JLK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

866895:HBHAL RS02200
gene id: 866895:HBHAL_RS02200
uniprot id: I0JI15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

866895:HBHAL RS04485
gene id: 866895:HBHAL_RS04485
uniprot id: I0JJE8
names: Similarity
messages: Belongs to the TPP enzyme family.

866895:HBHAL RS12060
gene id: 866895:HBHAL_RS12060
uniprot id: I0JNV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

866895:HBHAL RS08850
gene id: 866895:HBHAL_RS08850
uniprot id: I0JLX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS20050
gene id: 866895:HBHAL_RS20050
uniprot id: I0JTK7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

866895:HBHAL RS11955
gene id: 866895:HBHAL_RS11955
uniprot id: I0JNT0
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

866895:HBHAL RS00355
gene id: 866895:HBHAL_RS00355
uniprot id: I0JH32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

866895:HBHAL RS13010
gene id: 866895:HBHAL_RS13010
uniprot id: I0JPD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

866895:HBHAL RS12065
gene id: 866895:HBHAL_RS12065
uniprot id: I0JNV2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

866895:HBHAL RS10870
gene id: 866895:HBHAL_RS10870
uniprot id: I0JN50
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

866895:HBHAL RS11305
gene id: 866895:HBHAL_RS11305
uniprot id: I0JNE1
names: Similarity
messages: Belongs to the manganese catalase family.

866895:HBHAL RS13795
gene id: 866895:HBHAL_RS13795
uniprot id: I0JPU5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS15495
gene id: 866895:HBHAL_RS15495
uniprot id: I0JQU7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

866895:HBHAL RS07100
gene id: 866895:HBHAL_RS07100
uniprot id: I0JKW1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11855
gene id: 866895:HBHAL_RS11855
uniprot id: I0JNQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
messages: Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes.
messages: Homotetramer.

866895:HBHAL RS16190
gene id: 866895:HBHAL_RS16190
uniprot id: I0JR95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

866895:HBHAL RS13850
gene id: 866895:HBHAL_RS13850
uniprot id: I0JPV8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

866895:HBHAL RS20180
gene id: 866895:HBHAL_RS20180
uniprot id: I0JTN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

866895:HBHAL RS04550
gene id: 866895:HBHAL_RS04550
uniprot id: I0JJG1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

866895:HBHAL RS01835
gene id: 866895:HBHAL_RS01835
uniprot id: I0JHV9
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12000
gene id: 866895:HBHAL_RS12000
uniprot id: I0JNT9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

866895:HBHAL RS03125
gene id: 866895:HBHAL_RS03125
uniprot id: I0JIK7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

866895:HBHAL RS00735
gene id: 866895:HBHAL_RS00735
uniprot id: I0JH93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

866895:HBHAL RS06225
gene id: 866895:HBHAL_RS06225
uniprot id: I0JKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS10445
gene id: 866895:HBHAL_RS10445
uniprot id: I0JMW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

866895:HBHAL RS08920
gene id: 866895:HBHAL_RS08920
uniprot id: I0JLZ3
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS15340
gene id: 866895:HBHAL_RS15340
uniprot id: I0JQR1
names: Similarity
messages: Belongs to the acyltransferase 3 family.

866895:HBHAL RS17075
gene id: 866895:HBHAL_RS17075
uniprot id: I0JRU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

866895:HBHAL RS17405
gene id: 866895:HBHAL_RS17405
uniprot id: I0JS13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

866895:HBHAL RS07730
gene id: 866895:HBHAL_RS07730
uniprot id: I0JL84
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

866895:HBHAL RS20430
gene id: 866895:HBHAL_RS20430
uniprot id: I0JQG8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS18115
gene id: 866895:HBHAL_RS18115
uniprot id: I0JSF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

866895:HBHAL RS19270
gene id: 866895:HBHAL_RS19270
uniprot id: I0JT50
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS17990
gene id: 866895:HBHAL_RS17990
uniprot id: I0JSD4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS10755
gene id: 866895:HBHAL_RS10755
uniprot id: I0JN27
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

866895:HBHAL RS09375
gene id: 866895:HBHAL_RS09375
uniprot id: I0JM89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

866895:HBHAL RS03830
gene id: 866895:HBHAL_RS03830
uniprot id: I0JJ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

866895:HBHAL RS08950
gene id: 866895:HBHAL_RS08950
uniprot id: I0JLZ9
names: Similarity
messages: Belongs to the UPF0637 family.

866895:HBHAL RS11275
gene id: 866895:HBHAL_RS11275
uniprot id: I0JND6
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Homodimer.

866895:HBHAL RS07810
gene id: 866895:HBHAL_RS07810
uniprot id: I0JL99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

866895:HBHAL RS03825
gene id: 866895:HBHAL_RS03825
uniprot id: I0JJ08
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

866895:HBHAL RS17465
gene id: 866895:HBHAL_RS17465
uniprot id: I0JS26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS01900
gene id: 866895:HBHAL_RS01900
uniprot id: I0JHX1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

866895:HBHAL RS09670
gene id: 866895:HBHAL_RS09670
uniprot id: I0JMF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS07825
gene id: 866895:HBHAL_RS07825
uniprot id: I0JLA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

866895:HBHAL RS01650
gene id: 866895:HBHAL_RS01650
uniprot id: I0JHS2
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS01760
gene id: 866895:HBHAL_RS01760
uniprot id: I0JHU4
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

866895:HBHAL RS08330
gene id: 866895:HBHAL_RS08330
uniprot id: I0JLL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

866895:HBHAL RS06070
gene id: 866895:HBHAL_RS06070
uniprot id: I0JK92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS17545
gene id: 866895:HBHAL_RS17545
uniprot id: I0JS45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS02395
gene id: 866895:HBHAL_RS02395
uniprot id: I0JI51
names: Similarity
messages: Belongs to the GbsR family.

866895:HBHAL RS07650
gene id: 866895:HBHAL_RS07650
uniprot id: I0JL66
names: Similarity
messages: Belongs to the EamA transporter family.

866895:HBHAL RS04150
gene id: 866895:HBHAL_RS04150
uniprot id: I0JJ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

866895:HBHAL RS02630
gene id: 866895:HBHAL_RS02630
uniprot id: I0JIA5
names: Similarity
messages: Belongs to the FGGY kinase family.

866895:HBHAL RS13775
gene id: 866895:HBHAL_RS13775
uniprot id: I0JPU1
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

866895:HBHAL RS00350
gene id: 866895:HBHAL_RS00350
uniprot id: I0JH31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS08875
gene id: 866895:HBHAL_RS08875
uniprot id: I0JLY2
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

866895:HBHAL RS15930
gene id: 866895:HBHAL_RS15930
uniprot id: I0JR34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

866895:HBHAL RS01475
gene id: 866895:HBHAL_RS01475
uniprot id: I0JHN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS07050
gene id: 866895:HBHAL_RS07050
uniprot id: I0JKV0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

866895:HBHAL RS14680
gene id: 866895:HBHAL_RS14680
uniprot id: I0JQC8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

866895:HBHAL RS14630
gene id: 866895:HBHAL_RS14630
uniprot id: I0JQB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

866895:HBHAL RS20110
gene id: 866895:HBHAL_RS20110
uniprot id: I0JTL9
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS01595
gene id: 866895:HBHAL_RS01595
uniprot id: I0JHR1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

866895:HBHAL RS17575
gene id: 866895:HBHAL_RS17575
uniprot id: I0JS51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

866895:HBHAL RS03150
gene id: 866895:HBHAL_RS03150
uniprot id: I0JIL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS02535
gene id: 866895:HBHAL_RS02535
uniprot id: I0JI83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS10980
gene id: 866895:HBHAL_RS10980
uniprot id: I0JN75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS15230
gene id: 866895:HBHAL_RS15230
uniprot id: I0JQN9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

866895:HBHAL RS10595
gene id: 866895:HBHAL_RS10595
uniprot id: I0JMZ3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

866895:HBHAL RS04055
gene id: 866895:HBHAL_RS04055
uniprot id: I0JJ57
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS03430
gene id: 866895:HBHAL_RS03430
uniprot id: I0JIS6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

866895:HBHAL RS02795
gene id: 866895:HBHAL_RS02795
uniprot id: I0JIE1
names: Similarity
messages: Belongs to the leucine-binding protein family.

866895:HBHAL RS13735
gene id: 866895:HBHAL_RS13735
uniprot id: I0JPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

866895:HBHAL RS18955
gene id: 866895:HBHAL_RS18955
uniprot id: I0JSY6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS04980
gene id: 866895:HBHAL_RS04980
uniprot id: I0JJP6
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12575
gene id: 866895:HBHAL_RS12575
uniprot id: I0JP51
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

866895:HBHAL RS04650
gene id: 866895:HBHAL_RS04650
uniprot id: I0JJI1
names: Similarity
messages: Belongs to the TrpC family.

866895:HBHAL RS09905
gene id: 866895:HBHAL_RS09905
uniprot id: I0JMJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

866895:HBHAL RS18925
gene id: 866895:HBHAL_RS18925
uniprot id: I0JSY0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

866895:HBHAL RS02090
gene id: 866895:HBHAL_RS02090
uniprot id: I0JI10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

866895:HBHAL RS18495
gene id: 866895:HBHAL_RS18495
uniprot id: I0JSN8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

866895:HBHAL RS11515
gene id: 866895:HBHAL_RS11515
uniprot id: I0JNI4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

866895:HBHAL RS06475
gene id: 866895:HBHAL_RS06475
uniprot id: I0JKI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS00165
gene id: 866895:HBHAL_RS00165
uniprot id: I0JGZ8
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

866895:HBHAL RS05860
gene id: 866895:HBHAL_RS05860
uniprot id: I0JK51
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS20185
gene id: 866895:HBHAL_RS20185
uniprot id: I0JTN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

866895:HBHAL RS13785
gene id: 866895:HBHAL_RS13785
uniprot id: I0JPU3
names: Similarity
messages: Belongs to the UPF0354 family.

866895:HBHAL RS06345
gene id: 866895:HBHAL_RS06345
uniprot id: I0JKF0
names: Similarity
messages: Belongs to the asparagine synthetase family.

866895:HBHAL RS15900
gene id: 866895:HBHAL_RS15900
uniprot id: I0JR28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS16830
gene id: 866895:HBHAL_RS16830
uniprot id: I0JRN8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

866895:HBHAL RS05420
gene id: 866895:HBHAL_RS05420
uniprot id: I0JJW8
names: Similarity
messages: Belongs to the EamA transporter family.

866895:HBHAL RS00145
gene id: 866895:HBHAL_RS00145
uniprot id: I0JGZ4
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

866895:HBHAL RS04570
gene id: 866895:HBHAL_RS04570
uniprot id: I0JJG5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

866895:HBHAL RS14585
gene id: 866895:HBHAL_RS14585
uniprot id: I0JQA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

866895:HBHAL RS00805
gene id: 866895:HBHAL_RS00805
uniprot id: I0JHA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

866895:HBHAL RS13515
gene id: 866895:HBHAL_RS13515
uniprot id: I0JPN8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS17605
gene id: 866895:HBHAL_RS17605
uniprot id: I0JS57
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS02625
gene id: 866895:HBHAL_RS02625
uniprot id: I0JIA3
names: Function
messages: Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.

866895:HBHAL RS01055
gene id: 866895:HBHAL_RS01055
uniprot id: I0JHE4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS04415
gene id: 866895:HBHAL_RS04415
uniprot id: I0JJD4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

866895:HBHAL RS02740
gene id: 866895:HBHAL_RS02740
uniprot id: I0JID0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS11155
gene id: 866895:HBHAL_RS11155
uniprot id: I0JNB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.
messages: Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan.

866895:HBHAL RS06275
gene id: 866895:HBHAL_RS06275
uniprot id: I0JKD6
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS05055
gene id: 866895:HBHAL_RS05055
uniprot id: I0JJR3
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Expression is growth phase-dependent, with maximal expression in the mid-exponential growth phase. Induced by high salt concentrations (at protein level).
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD) (By similarity).

866895:HBHAL RS12915
gene id: 866895:HBHAL_RS12915
uniprot id: I0JPC0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

866895:HBHAL RS05450
gene id: 866895:HBHAL_RS05450
uniprot id: I0JJX3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

866895:HBHAL RS15450
gene id: 866895:HBHAL_RS15450
uniprot id: I0JQT5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS17005
gene id: 866895:HBHAL_RS17005
uniprot id: D9ZZC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

866895:HBHAL RS18845
gene id: 866895:HBHAL_RS18845
uniprot id: I0JSW4
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

866895:HBHAL RS12830
gene id: 866895:HBHAL_RS12830
uniprot id: I0JPA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS13015
gene id: 866895:HBHAL_RS13015
uniprot id: I0JPE0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

866895:HBHAL RS02065
gene id: 866895:HBHAL_RS02065
uniprot id: I0JI05
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

866895:HBHAL RS17505
gene id: 866895:HBHAL_RS17505
uniprot id: I0JS34
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

866895:HBHAL RS03790
gene id: 866895:HBHAL_RS03790
uniprot id: I0JJ00
names: Similarity
messages: Belongs to the UPF0045 family.

866895:HBHAL RS05660
gene id: 866895:HBHAL_RS05660
uniprot id: I0JK12
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS16930
gene id: 866895:HBHAL_RS16930
uniprot id: I0JRR4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

866895:HBHAL RS13470
gene id: 866895:HBHAL_RS13470
uniprot id: I0JPM9
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS18385
gene id: 866895:HBHAL_RS18385
uniprot id: I0JSL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS16180
gene id: 866895:HBHAL_RS16180
uniprot id: I0JR93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

866895:HBHAL RS13615
gene id: 866895:HBHAL_RS13615
uniprot id: I0JPQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

866895:HBHAL RS07250
gene id: 866895:HBHAL_RS07250
uniprot id: I0JKZ3
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12970
gene id: 866895:HBHAL_RS12970
uniprot id: I0JPD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

866895:HBHAL RS20040
gene id: 866895:HBHAL_RS20040
uniprot id: I0JTK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

866895:HBHAL RS02015
gene id: 866895:HBHAL_RS02015
uniprot id: I0JHZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

866895:HBHAL RS17140
gene id: 866895:HBHAL_RS17140
uniprot id: I0JRW0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

866895:HBHAL RS15380
gene id: 866895:HBHAL_RS15380
uniprot id: I0JQR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09765
gene id: 866895:HBHAL_RS09765
uniprot id: I0JMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

866895:HBHAL RS00630
gene id: 866895:HBHAL_RS00630
uniprot id: I0JH71
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

866895:HBHAL RS11160
gene id: 866895:HBHAL_RS11160
uniprot id: I0JNB2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

866895:HBHAL RS18970
gene id: 866895:HBHAL_RS18970
uniprot id: I0JSY9
names: Similarity
messages: Belongs to the ThiD family.

866895:HBHAL RS00490
gene id: 866895:HBHAL_RS00490
uniprot id: I0JH58
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

866895:HBHAL RS11485
gene id: 866895:HBHAL_RS11485
uniprot id: I0JNH8
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

866895:HBHAL RS13270
gene id: 866895:HBHAL_RS13270
uniprot id: I0JPI6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

866895:HBHAL RS09005
gene id: 866895:HBHAL_RS09005
uniprot id: I0JM10
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

866895:HBHAL RS08870
gene id: 866895:HBHAL_RS08870
uniprot id: I0JLY1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

866895:HBHAL RS06535
gene id: 866895:HBHAL_RS06535
uniprot id: I0JKJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

866895:HBHAL RS14765
gene id: 866895:HBHAL_RS14765
uniprot id: I0JQE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

866895:HBHAL RS12440
gene id: 866895:HBHAL_RS12440
uniprot id: I0JP22
names: PTM
messages: Binds 1 heme c group covalently per subunit.

866895:HBHAL RS16700
gene id: 866895:HBHAL_RS16700
uniprot id: I0JRK7
names: Similarity
messages: Belongs to the peptidase C40 family.

866895:HBHAL RS16235
gene id: 866895:HBHAL_RS16235
uniprot id: I0JRA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

866895:HBHAL RS09495
gene id: 866895:HBHAL_RS09495
uniprot id: I0JMB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

866895:HBHAL RS00675
gene id: 866895:HBHAL_RS00675
uniprot id: I0JH81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

866895:HBHAL RS03820
gene id: 866895:HBHAL_RS03820
uniprot id: I0JJ07
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

866895:HBHAL RS17160
gene id: 866895:HBHAL_RS17160
uniprot id: I0JRW4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

866895:HBHAL RS09320
gene id: 866895:HBHAL_RS09320
uniprot id: I0JM78
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

866895:HBHAL RS18150
gene id: 866895:HBHAL_RS18150
uniprot id: I0JSG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

866895:HBHAL RS05285
gene id: 866895:HBHAL_RS05285
uniprot id: I0JJV9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

866895:HBHAL RS04405
gene id: 866895:HBHAL_RS04405
uniprot id: I0JJD2
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

866895:HBHAL RS15375
gene id: 866895:HBHAL_RS15375
uniprot id: I0JQR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS18120
gene id: 866895:HBHAL_RS18120
uniprot id: I0JSF7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

866895:HBHAL RS13730
gene id: 866895:HBHAL_RS13730
uniprot id: I0JPT2
names: Similarity
messages: Belongs to the MotB family.

866895:HBHAL RS04460
gene id: 866895:HBHAL_RS04460
uniprot id: I0JJE3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

866895:HBHAL RS00045
gene id: 866895:HBHAL_RS00045
uniprot id: I0JGX6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

866895:HBHAL RS13125
gene id: 866895:HBHAL_RS13125
uniprot id: I0JPG2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

866895:HBHAL RS11520
gene id: 866895:HBHAL_RS11520
uniprot id: I0JNI5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Component of the MPD complex composed of SpoIIM, SpoIIP and SpoIID.
messages: Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.

866895:HBHAL RS10875
gene id: 866895:HBHAL_RS10875
uniprot id: I0JN52
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS00615
gene id: 866895:HBHAL_RS00615
uniprot id: I0JH68
names: Similarity
messages: Belongs to the asparaginase 1 family.
messages: Belongs to the ycf81 family.

866895:HBHAL RS00825
gene id: 866895:HBHAL_RS00825
uniprot id: I0JHB1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

866895:HBHAL RS11635
gene id: 866895:HBHAL_RS11635
uniprot id: I0JNK8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS12580
gene id: 866895:HBHAL_RS12580
uniprot id: I0JP52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

866895:HBHAL RS17585
gene id: 866895:HBHAL_RS17585
uniprot id: I0JS53
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS08790
gene id: 866895:HBHAL_RS08790
uniprot id: I0JLW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

866895:HBHAL RS09225
gene id: 866895:HBHAL_RS09225
uniprot id: I0JM57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

866895:HBHAL RS02410
gene id: 866895:HBHAL_RS02410
uniprot id: I0JI55
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

866895:HBHAL RS19050
gene id: 866895:HBHAL_RS19050
uniprot id: I0JT05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

866895:HBHAL RS13290
gene id: 866895:HBHAL_RS13290
uniprot id: I0JPJ0
names: Similarity
messages: Belongs to the thioredoxin family.

866895:HBHAL RS11900
gene id: 866895:HBHAL_RS11900
uniprot id: I0JNR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

866895:HBHAL RS09775
gene id: 866895:HBHAL_RS09775
uniprot id: I0JMH3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

866895:HBHAL RS04990
gene id: 866895:HBHAL_RS04990
uniprot id: I0JJQ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS13525
gene id: 866895:HBHAL_RS13525
uniprot id: I0JPP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

866895:HBHAL RS13485
gene id: 866895:HBHAL_RS13485
uniprot id: I0JPN2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

866895:HBHAL RS08295
gene id: 866895:HBHAL_RS08295
uniprot id: I0JLK6
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

866895:HBHAL RS02810
gene id: 866895:HBHAL_RS02810
uniprot id: I0JIE4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS10110
gene id: 866895:HBHAL_RS10110
uniprot id: I0JMP3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS09870
gene id: 866895:HBHAL_RS09870
uniprot id: I0JMJ2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

866895:HBHAL RS21905
gene id: 866895:HBHAL_RS21905
uniprot id: I0JHU6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

866895:HBHAL RS10330
gene id: 866895:HBHAL_RS10330
uniprot id: I0JMT8
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

866895:HBHAL RS19245
gene id: 866895:HBHAL_RS19245
uniprot id: I0JT46
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

866895:HBHAL RS15100
gene id: 866895:HBHAL_RS15100
uniprot id: I0JQL4
names: Similarity
messages: Belongs to the IMPACT family.

866895:HBHAL RS04675
gene id: 866895:HBHAL_RS04675
uniprot id: I0JJI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

866895:HBHAL RS19055
gene id: 866895:HBHAL_RS19055
uniprot id: I0JT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09810
gene id: 866895:HBHAL_RS09810
uniprot id: I0JMI0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

866895:HBHAL RS10590
gene id: 866895:HBHAL_RS10590
uniprot id: I0JMZ2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

866895:HBHAL RS17165
gene id: 866895:HBHAL_RS17165
uniprot id: I0JRW5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS01700
gene id: 866895:HBHAL_RS01700
uniprot id: I0JHT2
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS02915
gene id: 866895:HBHAL_RS02915
uniprot id: I0JIG5
names: Subcellular Location Annotation
messages: Cell membrane

866895:HBHAL RS18745
gene id: 866895:HBHAL_RS18745
uniprot id: I0JSU2
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12755
gene id: 866895:HBHAL_RS12755
uniprot id: I0JP88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

866895:HBHAL RS12480
gene id: 866895:HBHAL_RS12480
uniprot id: I0JP29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

866895:HBHAL RS12275
gene id: 866895:HBHAL_RS12275
uniprot id: I0JNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS20170
gene id: 866895:HBHAL_RS20170
uniprot id: I0JTN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS15215
gene id: 866895:HBHAL_RS15215
uniprot id: I0JQN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS06160
gene id: 866895:HBHAL_RS06160
uniprot id: I0JKB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS13355
gene id: 866895:HBHAL_RS13355
uniprot id: I0JPK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

866895:HBHAL RS14320
gene id: 866895:HBHAL_RS14320
uniprot id: I0JQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS13295
gene id: 866895:HBHAL_RS13295
uniprot id: I0JPJ1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

866895:HBHAL RS16205
gene id: 866895:HBHAL_RS16205
uniprot id: I0JR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

866895:HBHAL RS14375
gene id: 866895:HBHAL_RS14375
uniprot id: D9ZZC4
names: Cofactor
messages: Binds 1 FAD per subunit.

866895:HBHAL RS06130
gene id: 866895:HBHAL_RS06130
uniprot id: I0JKA6
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS00330
gene id: 866895:HBHAL_RS00330
uniprot id: I0JH27
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.

866895:HBHAL RS09310
gene id: 866895:HBHAL_RS09310
uniprot id: I0JM76
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

866895:HBHAL RS19335
gene id: 866895:HBHAL_RS19335
uniprot id: I0JT64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

866895:HBHAL RS18400
gene id: 866895:HBHAL_RS18400
uniprot id: I0JSL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

866895:HBHAL RS07235
gene id: 866895:HBHAL_RS07235
uniprot id: I0JKZ0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

866895:HBHAL RS19805
gene id: 866895:HBHAL_RS19805
uniprot id: I0JTF8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

866895:HBHAL RS00875
gene id: 866895:HBHAL_RS00875
uniprot id: I0JHC1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

866895:HBHAL RS18275
gene id: 866895:HBHAL_RS18275
uniprot id: I0JSJ0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

866895:HBHAL RS03950
gene id: 866895:HBHAL_RS03950
uniprot id: I0JJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS06040
gene id: 866895:HBHAL_RS06040
uniprot id: I0JK87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

866895:HBHAL RS09415
gene id: 866895:HBHAL_RS09415
uniprot id: I0JM97
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

866895:HBHAL RS16765
gene id: 866895:HBHAL_RS16765
uniprot id: I0JRM2
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS02400
gene id: 866895:HBHAL_RS02400
uniprot id: I0JI52
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

866895:HBHAL RS15725
gene id: 866895:HBHAL_RS15725
uniprot id: I0JQZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

866895:HBHAL RS07635
gene id: 866895:HBHAL_RS07635
uniprot id: I0JL63
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS09795
gene id: 866895:HBHAL_RS09795
uniprot id: I0JMH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

866895:HBHAL RS10405
gene id: 866895:HBHAL_RS10405
uniprot id: I0JMV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

866895:HBHAL RS18395
gene id: 866895:HBHAL_RS18395
uniprot id: I0JSL7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

866895:HBHAL RS11195
gene id: 866895:HBHAL_RS11195
uniprot id: I0JNB9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

866895:HBHAL RS10125
gene id: 866895:HBHAL_RS10125
uniprot id: I0JMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

866895:HBHAL RS01490
gene id: 866895:HBHAL_RS01490
uniprot id: I0JHN5
names: Similarity
messages: Belongs to the EamA transporter family.

866895:HBHAL RS02530
gene id: 866895:HBHAL_RS02530
uniprot id: I0JI82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS12540
gene id: 866895:HBHAL_RS12540
uniprot id: I0JP44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

866895:HBHAL RS12425
gene id: 866895:HBHAL_RS12425
uniprot id: I0JP19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

866895:HBHAL RS03175
gene id: 866895:HBHAL_RS03175
uniprot id: I0JIL8
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

866895:HBHAL RS19915
gene id: 866895:HBHAL_RS19915
uniprot id: I0JTI2
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS09475
gene id: 866895:HBHAL_RS09475
uniprot id: I0JMB0
names: Similarity
messages: Belongs to the universal stress protein A family.

866895:HBHAL RS12175
gene id: 866895:HBHAL_RS12175
uniprot id: I0JNX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

866895:HBHAL RS01480
gene id: 866895:HBHAL_RS01480
uniprot id: I0JHN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

866895:HBHAL RS17315
gene id: 866895:HBHAL_RS17315
uniprot id: I0JRZ5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

866895:HBHAL RS15805
gene id: 866895:HBHAL_RS15805
uniprot id: I0JR11
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS02750
gene id: 866895:HBHAL_RS02750
uniprot id: I0JID2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

866895:HBHAL RS18410
gene id: 866895:HBHAL_RS18410
uniprot id: I0JSM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

866895:HBHAL RS16690
gene id: 866895:HBHAL_RS16690
uniprot id: I0JRK4
names: Similarity
messages: Belongs to the CpsD/CapB family.

866895:HBHAL RS00245
gene id: 866895:HBHAL_RS00245
uniprot id: I0JH10
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

866895:HBHAL RS15000
gene id: 866895:HBHAL_RS15000
uniprot id: I0JQJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

866895:HBHAL RS04720
gene id: 866895:HBHAL_RS04720
uniprot id: I0JJJ4
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

866895:HBHAL RS14620
gene id: 866895:HBHAL_RS14620
uniprot id: I0JQB6
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

866895:HBHAL RS19370
gene id: 866895:HBHAL_RS19370
uniprot id: I0JT69
names: Similarity
messages: Belongs to the universal stress protein A family.

866895:HBHAL RS09300
gene id: 866895:HBHAL_RS09300
uniprot id: I0JM74
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

866895:HBHAL RS10450
gene id: 866895:HBHAL_RS10450
uniprot id: I0JMW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

866895:HBHAL RS05035
gene id: 866895:HBHAL_RS05035
uniprot id: I0JJR0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

866895:HBHAL RS00190
gene id: 866895:HBHAL_RS00190
uniprot id: I0JH03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

866895:HBHAL RS01600
gene id: 866895:HBHAL_RS01600
uniprot id: I0JHR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

866895:HBHAL RS20190
gene id: 866895:HBHAL_RS20190
uniprot id: I0JTN6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

866895:HBHAL RS18325
gene id: 866895:HBHAL_RS18325
uniprot id: I0JSK1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

866895:HBHAL RS01880
gene id: 866895:HBHAL_RS01880
uniprot id: I0JHW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS00335
gene id: 866895:HBHAL_RS00335
uniprot id: I0JH28
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

866895:HBHAL RS03845
gene id: 866895:HBHAL_RS03845
uniprot id: I0JJ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

866895:HBHAL RS12960
gene id: 866895:HBHAL_RS12960
uniprot id: I0JPC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

866895:HBHAL RS09950
gene id: 866895:HBHAL_RS09950
uniprot id: I0JMK8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

866895:HBHAL RS01315
gene id: 866895:HBHAL_RS01315
uniprot id: I0JHJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09205
gene id: 866895:HBHAL_RS09205
uniprot id: I0JM53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

866895:HBHAL RS08065
gene id: 866895:HBHAL_RS08065
uniprot id: I0JLF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS09280
gene id: 866895:HBHAL_RS09280
uniprot id: I0JM70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

866895:HBHAL RS04730
gene id: 866895:HBHAL_RS04730
uniprot id: I0JJJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS06235
gene id: 866895:HBHAL_RS06235
uniprot id: I0JKD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

866895:HBHAL RS11585
gene id: 866895:HBHAL_RS11585
uniprot id: I0JNJ8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11010
gene id: 866895:HBHAL_RS11010
uniprot id: I0JN82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

866895:HBHAL RS07155
gene id: 866895:HBHAL_RS07155
uniprot id: I0JKX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS10370
gene id: 866895:HBHAL_RS10370
uniprot id: I0JMU6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

866895:HBHAL RS09190
gene id: 866895:HBHAL_RS09190
uniprot id: I0JM50
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS18875
gene id: 866895:HBHAL_RS18875
uniprot id: I0JSX0
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11505
gene id: 866895:HBHAL_RS11505
uniprot id: I0JNI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

866895:HBHAL RS14750
gene id: 866895:HBHAL_RS14750
uniprot id: I0JQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

866895:HBHAL RS10140
gene id: 866895:HBHAL_RS10140
uniprot id: I0JMP9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS12155
gene id: 866895:HBHAL_RS12155
uniprot id: I0JNX1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

866895:HBHAL RS13835
gene id: 866895:HBHAL_RS13835
uniprot id: I0JPV5
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

866895:HBHAL RS12150
gene id: 866895:HBHAL_RS12150
uniprot id: I0JNX0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS06495
gene id: 866895:HBHAL_RS06495
uniprot id: I0JKI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS08815
gene id: 866895:HBHAL_RS08815
uniprot id: I0JLX0
names: Similarity
messages: Belongs to the UPF0180 family.

866895:HBHAL RS00140
gene id: 866895:HBHAL_RS00140
uniprot id: I0JGZ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

866895:HBHAL RS03995
gene id: 866895:HBHAL_RS03995
uniprot id: I0JJ45
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS07740
gene id: 866895:HBHAL_RS07740
uniprot id: I0JL86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

866895:HBHAL RS07805
gene id: 866895:HBHAL_RS07805
uniprot id: I0JL98
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS05700
gene id: 866895:HBHAL_RS05700
uniprot id: I0JK20
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

866895:HBHAL RS14280
gene id: 866895:HBHAL_RS14280
uniprot id: I0JQ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS04775
gene id: 866895:HBHAL_RS04775
uniprot id: I0JJK5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS18765
gene id: 866895:HBHAL_RS18765
uniprot id: I0JSU6
names: Similarity
messages: Belongs to the IucA/IucC family.

866895:HBHAL RS04135
gene id: 866895:HBHAL_RS04135
uniprot id: I0JJ74
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

866895:HBHAL RS08155
gene id: 866895:HBHAL_RS08155
uniprot id: I0JLH6
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

866895:HBHAL RS13335
gene id: 866895:HBHAL_RS13335
uniprot id: I0JPK0
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS13810
gene id: 866895:HBHAL_RS13810
uniprot id: I0JPU9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

866895:HBHAL RS09955
gene id: 866895:HBHAL_RS09955
uniprot id: I0JMK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

866895:HBHAL RS11255
gene id: 866895:HBHAL_RS11255
uniprot id: I0JND2
names: Similarity
messages: Belongs to the asparaginase 1 family.

866895:HBHAL RS11565
gene id: 866895:HBHAL_RS11565
uniprot id: I0JNJ5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS18280
gene id: 866895:HBHAL_RS18280
uniprot id: I0JSJ1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS18860
gene id: 866895:HBHAL_RS18860
uniprot id: I0JSW7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

866895:HBHAL RS14770
gene id: 866895:HBHAL_RS14770
uniprot id: I0JQE5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

866895:HBHAL RS17100
gene id: 866895:HBHAL_RS17100
uniprot id: I0JRV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

866895:HBHAL RS19200
gene id: 866895:HBHAL_RS19200
uniprot id: I0JT35
names: Similarity
messages: Belongs to the peptidase S8 family.

866895:HBHAL RS05580
gene id: 866895:HBHAL_RS05580
uniprot id: I0JJZ6
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

866895:HBHAL RS19160
gene id: 866895:HBHAL_RS19160
uniprot id: I0JT27
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS11360
gene id: 866895:HBHAL_RS11360
uniprot id: I0JNF3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS19440
gene id: 866895:HBHAL_RS19440
uniprot id: I0JT83
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS12875
gene id: 866895:HBHAL_RS12875
uniprot id: I0JPB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS18795
gene id: 866895:HBHAL_RS18795
uniprot id: I0JSV3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

866895:HBHAL RS11000
gene id: 866895:HBHAL_RS11000
uniprot id: I0JN80
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

866895:HBHAL RS12555
gene id: 866895:HBHAL_RS12555
uniprot id: I0JP47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

866895:HBHAL RS11930
gene id: 866895:HBHAL_RS11930
uniprot id: I0JNS4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

866895:HBHAL RS00865
gene id: 866895:HBHAL_RS00865
uniprot id: I0JHB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

866895:HBHAL RS10275
gene id: 866895:HBHAL_RS10275
uniprot id: I0JMS6
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS18300
gene id: 866895:HBHAL_RS18300
uniprot id: I0JSJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS12475
gene id: 866895:HBHAL_RS12475
uniprot id: I0JP28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

866895:HBHAL RS07135
gene id: 866895:HBHAL_RS07135
uniprot id: I0JKX0
names: Similarity
messages: Belongs to the universal stress protein A family.

866895:HBHAL RS09435
gene id: 866895:HBHAL_RS09435
uniprot id: I0JMA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS20470
gene id: 866895:HBHAL_RS20470
uniprot id: I0JRM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

866895:HBHAL RS06985
gene id: 866895:HBHAL_RS06985
uniprot id: I0JKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

866895:HBHAL RS09215
gene id: 866895:HBHAL_RS09215
uniprot id: I0JM55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

866895:HBHAL RS11015
gene id: 866895:HBHAL_RS11015
uniprot id: I0JN83
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS02075
gene id: 866895:HBHAL_RS02075
uniprot id: I0JI07
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

866895:HBHAL RS02910
gene id: 866895:HBHAL_RS02910
uniprot id: I0JIG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS05050
gene id: 866895:HBHAL_RS05050
uniprot id: A1DZZ3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. YrrT family.
messages: Could be a S-adenosyl-L-methionine-dependent methyltransferase.

866895:HBHAL RS07815
gene id: 866895:HBHAL_RS07815
uniprot id: I0JLA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS17595
gene id: 866895:HBHAL_RS17595
uniprot id: I0JS55
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

866895:HBHAL RS12825
gene id: 866895:HBHAL_RS12825
uniprot id: I0JPA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS02710
gene id: 866895:HBHAL_RS02710
uniprot id: I0JIC2
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

866895:HBHAL RS13980
gene id: 866895:HBHAL_RS13980
uniprot id: I0JPY4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS17780
gene id: 866895:HBHAL_RS17780
uniprot id: I0JS91
names: Similarity
messages: Belongs to the acyltransferase 3 family.

866895:HBHAL RS13880
gene id: 866895:HBHAL_RS13880
uniprot id: I0JPW3
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS04665
gene id: 866895:HBHAL_RS04665
uniprot id: I0JJI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

866895:HBHAL RS03575
gene id: 866895:HBHAL_RS03575
uniprot id: I0JIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS08225
gene id: 866895:HBHAL_RS08225
uniprot id: I0JLI9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

866895:HBHAL RS09035
gene id: 866895:HBHAL_RS09035
uniprot id: I0JM17
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS20045
gene id: 866895:HBHAL_RS20045
uniprot id: I0JTK6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

866895:HBHAL RS09025
gene id: 866895:HBHAL_RS09025
uniprot id: I0JM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS01425
gene id: 866895:HBHAL_RS01425
uniprot id: I0JHL9
names: Similarity
messages: Belongs to the peptidase S51 family.

866895:HBHAL RS04750
gene id: 866895:HBHAL_RS04750
uniprot id: I0JJK0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

866895:HBHAL RS05945
gene id: 866895:HBHAL_RS05945
uniprot id: I0JK68
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

866895:HBHAL RS07840
gene id: 866895:HBHAL_RS07840
uniprot id: I0JLA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

866895:HBHAL RS03960
gene id: 866895:HBHAL_RS03960
uniprot id: I0JJ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

866895:HBHAL RS05405
gene id: 866895:HBHAL_RS05405
uniprot id: I0JJW5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

866895:HBHAL RS14675
gene id: 866895:HBHAL_RS14675
uniprot id: I0JQC7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

866895:HBHAL RS09265
gene id: 866895:HBHAL_RS09265
uniprot id: I0JM66
names: Similarity
messages: Belongs to the YggT family.

866895:HBHAL RS13990
gene id: 866895:HBHAL_RS13990
uniprot id: I0JPY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

866895:HBHAL RS06860
gene id: 866895:HBHAL_RS06860
uniprot id: I0JKR2
names: Similarity
messages: Belongs to the RibF family.

866895:HBHAL RS15990
gene id: 866895:HBHAL_RS15990
uniprot id: I0JR49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS10400
gene id: 866895:HBHAL_RS10400
uniprot id: I0JMV1
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

866895:HBHAL RS10390
gene id: 866895:HBHAL_RS10390
uniprot id: I0JMU9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

866895:HBHAL RS10520
gene id: 866895:HBHAL_RS10520
uniprot id: I0JMX8
names: Similarity
messages: Belongs to the HesB/IscA family.

866895:HBHAL RS12585
gene id: 866895:HBHAL_RS12585
uniprot id: I0JP53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

866895:HBHAL RS11215
gene id: 866895:HBHAL_RS11215
uniprot id: I0JNC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS19965
gene id: 866895:HBHAL_RS19965
uniprot id: I0JTJ2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

866895:HBHAL RS07210
gene id: 866895:HBHAL_RS07210
uniprot id: I0JKY5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

866895:HBHAL RS10995
gene id: 866895:HBHAL_RS10995
uniprot id: I0JN79
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

866895:HBHAL RS18580
gene id: 866895:HBHAL_RS18580
uniprot id: I0JSQ7
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

866895:HBHAL RS09935
gene id: 866895:HBHAL_RS09935
uniprot id: I0JMK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

866895:HBHAL RS02720
gene id: 866895:HBHAL_RS02720
uniprot id: I0JIC6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS06425
gene id: 866895:HBHAL_RS06425
uniprot id: I0JKG8
names: Similarity
messages: Belongs to the MoaD family.

866895:HBHAL RS10065
gene id: 866895:HBHAL_RS10065
uniprot id: I0JMN1
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

866895:HBHAL RS12180
gene id: 866895:HBHAL_RS12180
uniprot id: I0JNX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

866895:HBHAL RS02070
gene id: 866895:HBHAL_RS02070
uniprot id: I0JI06
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

866895:HBHAL RS16760
gene id: 866895:HBHAL_RS16760
uniprot id: I0JRM1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

866895:HBHAL RS05770
gene id: 866895:HBHAL_RS05770
uniprot id: I0JK34
names: Similarity
messages: Belongs to the peptidase S66 family.

866895:HBHAL RS08585
gene id: 866895:HBHAL_RS08585
uniprot id: I0JLR9
names: Similarity
messages: Belongs to the glutamine synthetase family.

866895:HBHAL RS06705
gene id: 866895:HBHAL_RS06705
uniprot id: I0JKN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS14985
gene id: 866895:HBHAL_RS14985
uniprot id: I0JQJ0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

866895:HBHAL RS02425
gene id: 866895:HBHAL_RS02425
uniprot id: I0JI58
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS05820
gene id: 866895:HBHAL_RS05820
uniprot id: I0JK43
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS16615
gene id: 866895:HBHAL_RS16615
uniprot id: I0JRI9
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

866895:HBHAL RS06615
gene id: 866895:HBHAL_RS06615
uniprot id: I0JKK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

866895:HBHAL RS04655
gene id: 866895:HBHAL_RS04655
uniprot id: I0JJI2
names: Similarity
messages: Belongs to the TrpF family.

866895:HBHAL RS14550
gene id: 866895:HBHAL_RS14550
uniprot id: I0JQA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

866895:HBHAL RS14635
gene id: 866895:HBHAL_RS14635
uniprot id: I0JQB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

866895:HBHAL RS18430
gene id: 866895:HBHAL_RS18430
uniprot id: I0JSM5
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS19040
gene id: 866895:HBHAL_RS19040
uniprot id: I0JT03
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS10855
gene id: 866895:HBHAL_RS10855
uniprot id: I0JN47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS10525
gene id: 866895:HBHAL_RS10525
uniprot id: I0JMX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

866895:HBHAL RS00775
gene id: 866895:HBHAL_RS00775
uniprot id: I0JHA1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

866895:HBHAL RS18915
gene id: 866895:HBHAL_RS18915
uniprot id: I0JSX8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

866895:HBHAL RS15575
gene id: 866895:HBHAL_RS15575
uniprot id: I0JQW4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS04575
gene id: 866895:HBHAL_RS04575
uniprot id: I0JJG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

866895:HBHAL RS03500
gene id: 866895:HBHAL_RS03500
uniprot id: I0JIU0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

866895:HBHAL RS10355
gene id: 866895:HBHAL_RS10355
uniprot id: I0JMU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

866895:HBHAL RS12785
gene id: 866895:HBHAL_RS12785
uniprot id: I0JP93
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

866895:HBHAL RS12290
gene id: 866895:HBHAL_RS12290
uniprot id: I0JNZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS16620
gene id: 866895:HBHAL_RS16620
uniprot id: I0JRJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

866895:HBHAL RS08855
gene id: 866895:HBHAL_RS08855
uniprot id: I0JLX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

866895:HBHAL RS11145
gene id: 866895:HBHAL_RS11145
uniprot id: I0JNA9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

866895:HBHAL RS05640
gene id: 866895:HBHAL_RS05640
uniprot id: I0JK08
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

866895:HBHAL RS08910
gene id: 866895:HBHAL_RS08910
uniprot id: I0JLY9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

866895:HBHAL RS14505
gene id: 866895:HBHAL_RS14505
uniprot id: I0JQ93
names: Cofactor
messages: Can also use Mn(2+) ion.

866895:HBHAL RS08640
gene id: 866895:HBHAL_RS08640
uniprot id: I0JLT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

866895:HBHAL RS02265
gene id: 866895:HBHAL_RS02265
uniprot id: I0JI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

866895:HBHAL RS12600
gene id: 866895:HBHAL_RS12600
uniprot id: I0JP56
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

866895:HBHAL RS18805
gene id: 866895:HBHAL_RS18805
uniprot id: I0JSV5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

866895:HBHAL RS12840
gene id: 866895:HBHAL_RS12840
uniprot id: I0JPA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS13995
gene id: 866895:HBHAL_RS13995
uniprot id: I0JPY7
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

866895:HBHAL RS16840
gene id: 866895:HBHAL_RS16840
uniprot id: I0JRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

866895:HBHAL RS18310
gene id: 866895:HBHAL_RS18310
uniprot id: I0JSJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

866895:HBHAL RS13030
gene id: 866895:HBHAL_RS13030
uniprot id: I0JPE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

866895:HBHAL RS00635
gene id: 866895:HBHAL_RS00635
uniprot id: I0JH72
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

866895:HBHAL RS12070
gene id: 866895:HBHAL_RS12070
uniprot id: I0JNV3
names: Similarity
messages: Belongs to the asp23 family.

866895:HBHAL RS14295
gene id: 866895:HBHAL_RS14295
uniprot id: I0JQ51
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

866895:HBHAL RS19350
gene id: 866895:HBHAL_RS19350
uniprot id: I0JT66
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

866895:HBHAL RS00640
gene id: 866895:HBHAL_RS00640
uniprot id: I0JH73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

866895:HBHAL RS05250
gene id: 866895:HBHAL_RS05250
uniprot id: I0JJV1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS13825
gene id: 866895:HBHAL_RS13825
uniprot id: I0JPV2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

866895:HBHAL RS06595
gene id: 866895:HBHAL_RS06595
uniprot id: I0JKK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS18870
gene id: 866895:HBHAL_RS18870
uniprot id: I0JSW9
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS09825
gene id: 866895:HBHAL_RS09825
uniprot id: I0JMI3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

866895:HBHAL RS09290
gene id: 866895:HBHAL_RS09290
uniprot id: I0JM72
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

866895:HBHAL RS17400
gene id: 866895:HBHAL_RS17400
uniprot id: I0JS12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

866895:HBHAL RS00480
gene id: 866895:HBHAL_RS00480
uniprot id: I0JH56
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

866895:HBHAL RS04290
gene id: 866895:HBHAL_RS04290
uniprot id: I0JJA6
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS04210
gene id: 866895:HBHAL_RS04210
uniprot id: I0JJ90
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

866895:HBHAL RS02230
gene id: 866895:HBHAL_RS02230
uniprot id: I0JI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS13320
gene id: 866895:HBHAL_RS13320
uniprot id: I0JPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

866895:HBHAL RS01260
gene id: 866895:HBHAL_RS01260
uniprot id: I0JHI3
names: Similarity
messages: Belongs to the TPP enzyme family.

866895:HBHAL RS00700
gene id: 866895:HBHAL_RS00700
uniprot id: I0JH86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

866895:HBHAL RS13055
gene id: 866895:HBHAL_RS13055
uniprot id: I0JPE8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

866895:HBHAL RS04480
gene id: 866895:HBHAL_RS04480
uniprot id: I0JJE7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS00200
gene id: 866895:HBHAL_RS00200
uniprot id: I0JH05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

866895:HBHAL RS17470
gene id: 866895:HBHAL_RS17470
uniprot id: I0JS27
names: Similarity
messages: Belongs to the UPF0340 family.

866895:HBHAL RS09350
gene id: 866895:HBHAL_RS09350
uniprot id: I0JM84
names: Similarity
messages: Belongs to the YicC/YloC family.

866895:HBHAL RS09880
gene id: 866895:HBHAL_RS09880
uniprot id: I0JMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

866895:HBHAL RS17045
gene id: 866895:HBHAL_RS17045
uniprot id: I0JRU1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS04615
gene id: 866895:HBHAL_RS04615
uniprot id: I0JJH4
names: Similarity
messages: Belongs to the UPF0145 family.

866895:HBHAL RS05225
gene id: 866895:HBHAL_RS05225
uniprot id: I0JJU5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

866895:HBHAL RS10925
gene id: 866895:HBHAL_RS10925
uniprot id: I0JN63
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS04635
gene id: 866895:HBHAL_RS04635
uniprot id: I0JJH8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

866895:HBHAL RS12845
gene id: 866895:HBHAL_RS12845
uniprot id: I0JPA6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

866895:HBHAL RS12030
gene id: 866895:HBHAL_RS12030
uniprot id: I0JNU4
names: Similarity
messages: Belongs to the TlyA family.

866895:HBHAL RS02715
gene id: 866895:HBHAL_RS02715
uniprot id: I0JIC3
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

866895:HBHAL RS18435
gene id: 866895:HBHAL_RS18435
uniprot id: I0JSM6
names: Subcellular Location Annotation
messages: Cell membrane

866895:HBHAL RS12335
gene id: 866895:HBHAL_RS12335
uniprot id: I0JP07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

866895:HBHAL RS11035
gene id: 866895:HBHAL_RS11035
uniprot id: I0JN87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

866895:HBHAL RS14820
gene id: 866895:HBHAL_RS14820
uniprot id: I0JQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

866895:HBHAL RS07145
gene id: 866895:HBHAL_RS07145
uniprot id: I0JKX2
names: Similarity
messages: Belongs to the universal stress protein A family.

866895:HBHAL RS19105
gene id: 866895:HBHAL_RS19105
uniprot id: I0JT15
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

866895:HBHAL RS09380
gene id: 866895:HBHAL_RS09380
uniprot id: I0JM90
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

866895:HBHAL RS17480
gene id: 866895:HBHAL_RS17480
uniprot id: I0JS29
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

866895:HBHAL RS01505
gene id: 866895:HBHAL_RS01505
uniprot id: I0JHN8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

866895:HBHAL RS09535
gene id: 866895:HBHAL_RS09535
uniprot id: I0JMC2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

866895:HBHAL RS11970
gene id: 866895:HBHAL_RS11970
uniprot id: I0JNT3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

866895:HBHAL RS14810
gene id: 866895:HBHAL_RS14810
uniprot id: I0JQF2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

866895:HBHAL RS18700
gene id: 866895:HBHAL_RS18700
uniprot id: I0JST2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS02495
gene id: 866895:HBHAL_RS02495
uniprot id: I0JI75
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

866895:HBHAL RS08825
gene id: 866895:HBHAL_RS08825
uniprot id: I0JLX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

866895:HBHAL RS18520
gene id: 866895:HBHAL_RS18520
uniprot id: I0JSP4
names: Subunit
messages: Monomer.

866895:HBHAL RS04825
gene id: 866895:HBHAL_RS04825
uniprot id: I0JJL5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

866895:HBHAL RS05645
gene id: 866895:HBHAL_RS05645
uniprot id: I0JK09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS19425
gene id: 866895:HBHAL_RS19425
uniprot id: I0JT80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

866895:HBHAL RS12735
gene id: 866895:HBHAL_RS12735
uniprot id: I0JP84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

866895:HBHAL RS02815
gene id: 866895:HBHAL_RS02815
uniprot id: I0JIE5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

866895:HBHAL RS00315
gene id: 866895:HBHAL_RS00315
uniprot id: I0JH24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

866895:HBHAL RS09400
gene id: 866895:HBHAL_RS09400
uniprot id: I0JM94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

866895:HBHAL RS09660
gene id: 866895:HBHAL_RS09660
uniprot id: I0JME8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

866895:HBHAL RS13170
gene id: 866895:HBHAL_RS13170
uniprot id: I0JPG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09115
gene id: 866895:HBHAL_RS09115
uniprot id: I0JM34
names: Similarity
messages: Belongs to the peptidase S16 family.

866895:HBHAL RS05680
gene id: 866895:HBHAL_RS05680
uniprot id: I0JK16
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS08150
gene id: 866895:HBHAL_RS08150
uniprot id: I0JLH5
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

866895:HBHAL RS17125
gene id: 866895:HBHAL_RS17125
uniprot id: I0JRV7
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

866895:HBHAL RS04065
gene id: 866895:HBHAL_RS04065
uniprot id: I0JJ59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

866895:HBHAL RS09170
gene id: 866895:HBHAL_RS09170
uniprot id: I0JM46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

866895:HBHAL RS08085
gene id: 866895:HBHAL_RS08085
uniprot id: I0JLG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

866895:HBHAL RS14135
gene id: 866895:HBHAL_RS14135
uniprot id: I0JQ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

866895:HBHAL RS12890
gene id: 866895:HBHAL_RS12890
uniprot id: I0JPB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

866895:HBHAL RS11475
gene id: 866895:HBHAL_RS11475
uniprot id: I0JNH6
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

866895:HBHAL RS14875
gene id: 866895:HBHAL_RS14875
uniprot id: I0JQG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

866895:HBHAL RS02990
gene id: 866895:HBHAL_RS02990
uniprot id: I0JII0
names: Similarity
messages: Belongs to the FGGY kinase family.

866895:HBHAL RS03145
gene id: 866895:HBHAL_RS03145
uniprot id: D9ZZC6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

866895:HBHAL RS10115
gene id: 866895:HBHAL_RS10115
uniprot id: I0JMP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

866895:HBHAL RS11165
gene id: 866895:HBHAL_RS11165
uniprot id: I0JNB3
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

866895:HBHAL RS00035
gene id: 866895:HBHAL_RS00035
uniprot id: I0JGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

866895:HBHAL RS06785
gene id: 866895:HBHAL_RS06785
uniprot id: I0JKP7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

866895:HBHAL RS05500
gene id: 866895:HBHAL_RS05500
uniprot id: I0JJY1
names: Similarity
messages: Belongs to the GppA/Ppx family.

866895:HBHAL RS00830
gene id: 866895:HBHAL_RS00830
uniprot id: I0JHB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

866895:HBHAL RS02210
gene id: 866895:HBHAL_RS02210
uniprot id: I0JI17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

866895:HBHAL RS01365
gene id: 866895:HBHAL_RS01365
uniprot id: I0JHK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

866895:HBHAL RS01980
gene id: 866895:HBHAL_RS01980
uniprot id: I0JHY9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS06060
gene id: 866895:HBHAL_RS06060
uniprot id: I0JK90
names: Similarity
messages: Belongs to the GbsR family.

866895:HBHAL RS05515
gene id: 866895:HBHAL_RS05515
uniprot id: I0JJY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

866895:HBHAL RS03160
gene id: 866895:HBHAL_RS03160
uniprot id: I0JIL5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

866895:HBHAL RS13085
gene id: 866895:HBHAL_RS13085
uniprot id: I0JPF4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

866895:HBHAL RS03055
gene id: 866895:HBHAL_RS03055
uniprot id: I0JIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

866895:HBHAL RS12795
gene id: 866895:HBHAL_RS12795
uniprot id: I0JP95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS19310
gene id: 866895:HBHAL_RS19310
uniprot id: I0JT58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

866895:HBHAL RS06505
gene id: 866895:HBHAL_RS06505
uniprot id: I0JKI6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

866895:HBHAL RS11975
gene id: 866895:HBHAL_RS11975
uniprot id: I0JNT4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

866895:HBHAL RS05825
gene id: 866895:HBHAL_RS05825
uniprot id: I0JK44
names: Similarity
messages: Belongs to the universal stress protein A family.

866895:HBHAL RS04760
gene id: 866895:HBHAL_RS04760
uniprot id: I0JJK2
names: Similarity
messages: Belongs to the aldose epimerase family.

866895:HBHAL RS11545
gene id: 866895:HBHAL_RS11545
uniprot id: I0JNJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS14220
gene id: 866895:HBHAL_RS14220
uniprot id: I0JQ35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

866895:HBHAL RS03075
gene id: 866895:HBHAL_RS03075
uniprot id: I0JIJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

866895:HBHAL RS12525
gene id: 866895:HBHAL_RS12525
uniprot id: I0JP41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

866895:HBHAL RS04225
gene id: 866895:HBHAL_RS04225
uniprot id: I0JJ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

866895:HBHAL RS10035
gene id: 866895:HBHAL_RS10035
uniprot id: I0JMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

866895:HBHAL RS13670
gene id: 866895:HBHAL_RS13670
uniprot id: I0JPS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

866895:HBHAL RS04640
gene id: 866895:HBHAL_RS04640
uniprot id: I0JJH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

866895:HBHAL RS03130
gene id: 866895:HBHAL_RS03130
uniprot id: I0JIK8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

866895:HBHAL RS14355
gene id: 866895:HBHAL_RS14355
uniprot id: I0JQ64
names: Similarity
messages: Belongs to the ArsC family.

866895:HBHAL RS12850
gene id: 866895:HBHAL_RS12850
uniprot id: I0JPA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS10155
gene id: 866895:HBHAL_RS10155
uniprot id: I0JMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

866895:HBHAL RS10020
gene id: 866895:HBHAL_RS10020
uniprot id: I0JMM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

866895:HBHAL RS01730
gene id: 866895:HBHAL_RS01730
uniprot id: I0JHT8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

866895:HBHAL RS00080
gene id: 866895:HBHAL_RS00080
uniprot id: I0JGY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

866895:HBHAL RS20085
gene id: 866895:HBHAL_RS20085
uniprot id: I0JTL4
names: Similarity
messages: Belongs to the ParB family.

866895:HBHAL RS06455
gene id: 866895:HBHAL_RS06455
uniprot id: I0JKH6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

866895:HBHAL RS12205
gene id: 866895:HBHAL_RS12205
uniprot id: I0JNY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

866895:HBHAL RS10185
gene id: 866895:HBHAL_RS10185
uniprot id: I0JMQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

866895:HBHAL RS13490
gene id: 866895:HBHAL_RS13490
uniprot id: I0JPN3
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

866895:HBHAL RS13605
gene id: 866895:HBHAL_RS13605
uniprot id: I0JPQ6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

866895:HBHAL RS17760
gene id: 866895:HBHAL_RS17760
uniprot id: I0JS87
names: Similarity
messages: Belongs to the fructosamine kinase family.

866895:HBHAL RS13220
gene id: 866895:HBHAL_RS13220
uniprot id: I0JPH5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

866895:HBHAL RS17225
gene id: 866895:HBHAL_RS17225
uniprot id: I0JRX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS01570
gene id: 866895:HBHAL_RS01570
uniprot id: I0JHQ1
names: Similarity
messages: Belongs to the SCO1/2 family.

866895:HBHAL RS16185
gene id: 866895:HBHAL_RS16185
uniprot id: I0JR94
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

866895:HBHAL RS00295
gene id: 866895:HBHAL_RS00295
uniprot id: I0JH20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS13225
gene id: 866895:HBHAL_RS13225
uniprot id: I0JPH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

866895:HBHAL RS00725
gene id: 866895:HBHAL_RS00725
uniprot id: I0JH91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

866895:HBHAL RS15105
gene id: 866895:HBHAL_RS15105
uniprot id: I0JQL5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

866895:HBHAL RS06965
gene id: 866895:HBHAL_RS06965
uniprot id: I0JKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

866895:HBHAL RS18595
gene id: 866895:HBHAL_RS18595
uniprot id: I0JSR0
names: Similarity
messages: Belongs to the ThiD family.

866895:HBHAL RS10015
gene id: 866895:HBHAL_RS10015
uniprot id: I0JMM1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

866895:HBHAL RS16935
gene id: 866895:HBHAL_RS16935
uniprot id: I0JRR5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS13385
gene id: 866895:HBHAL_RS13385
uniprot id: I0JPL1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

866895:HBHAL RS13070
gene id: 866895:HBHAL_RS13070
uniprot id: I0JPF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS09345
gene id: 866895:HBHAL_RS09345
uniprot id: I0JM83
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

866895:HBHAL RS13365
gene id: 866895:HBHAL_RS13365
uniprot id: I0JPK6
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SspI family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

866895:HBHAL RS09305
gene id: 866895:HBHAL_RS09305
uniprot id: I0JM75
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

866895:HBHAL RS00695
gene id: 866895:HBHAL_RS00695
uniprot id: I0JH85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

866895:HBHAL RS12910
gene id: 866895:HBHAL_RS12910
uniprot id: I0JPB9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

866895:HBHAL RS17155
gene id: 866895:HBHAL_RS17155
uniprot id: I0JRW3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

866895:HBHAL RS19120
gene id: 866895:HBHAL_RS19120
uniprot id: I0JT18
names: Similarity
messages: Belongs to the DinB family.

866895:HBHAL RS09990
gene id: 866895:HBHAL_RS09990
uniprot id: I0JML6
names: Similarity
messages: Belongs to the FlgD family.

866895:HBHAL RS01340
gene id: 866895:HBHAL_RS01340
uniprot id: I0JHJ8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS10280
gene id: 866895:HBHAL_RS10280
uniprot id: I0JMS7
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12465
gene id: 866895:HBHAL_RS12465
uniprot id: I0JP26
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

866895:HBHAL RS17365
gene id: 866895:HBHAL_RS17365
uniprot id: I0JS05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

866895:HBHAL RS18835
gene id: 866895:HBHAL_RS18835
uniprot id: I0JSW2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

866895:HBHAL RS13440
gene id: 866895:HBHAL_RS13440
uniprot id: I0JPM3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

866895:HBHAL RS16210
gene id: 866895:HBHAL_RS16210
uniprot id: I0JR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

866895:HBHAL RS14535
gene id: 866895:HBHAL_RS14535
uniprot id: I0JQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

866895:HBHAL RS06140
gene id: 866895:HBHAL_RS06140
uniprot id: I0JKA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some proteins.

866895:HBHAL RS18950
gene id: 866895:HBHAL_RS18950
uniprot id: I0JSY5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS14880
gene id: 866895:HBHAL_RS14880
uniprot id: I0JQG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

866895:HBHAL RS09930
gene id: 866895:HBHAL_RS09930
uniprot id: I0JMK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

866895:HBHAL RS00810
gene id: 866895:HBHAL_RS00810
uniprot id: I0JHA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

866895:HBHAL RS03070
gene id: 866895:HBHAL_RS03070
uniprot id: I0JIJ6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

866895:HBHAL RS16595
gene id: 866895:HBHAL_RS16595
uniprot id: I0JRI6
names: Similarity
messages: Belongs to the acyltransferase 3 family.

866895:HBHAL RS06170
gene id: 866895:HBHAL_RS06170
uniprot id: I0JKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

866895:HBHAL RS07705
gene id: 866895:HBHAL_RS07705
uniprot id: I0JL77
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS01605
gene id: 866895:HBHAL_RS01605
uniprot id: I0JHR3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

866895:HBHAL RS12080
gene id: 866895:HBHAL_RS12080
uniprot id: I0JNV5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

866895:HBHAL RS15925
gene id: 866895:HBHAL_RS15925
uniprot id: I0JR33
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

866895:HBHAL RS18810
gene id: 866895:HBHAL_RS18810
uniprot id: I0JSV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

866895:HBHAL RS10395
gene id: 866895:HBHAL_RS10395
uniprot id: I0JMV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

866895:HBHAL RS17430
gene id: 866895:HBHAL_RS17430
uniprot id: I0JS18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

866895:HBHAL RS00470
gene id: 866895:HBHAL_RS00470
uniprot id: I0JH54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

866895:HBHAL RS08100
gene id: 866895:HBHAL_RS08100
uniprot id: I0JLG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

866895:HBHAL RS01940
gene id: 866895:HBHAL_RS01940
uniprot id: I0JHY0
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

866895:HBHAL RS11405
gene id: 866895:HBHAL_RS11405
uniprot id: I0JNG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

866895:HBHAL RS02275
gene id: 866895:HBHAL_RS02275
uniprot id: I0JI29
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

866895:HBHAL RS04270
gene id: 866895:HBHAL_RS04270
uniprot id: I0JJA2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS14165
gene id: 866895:HBHAL_RS14165
uniprot id: I0JQ24
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS15300
gene id: 866895:HBHAL_RS15300
uniprot id: I0JQQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

866895:HBHAL RS03890
gene id: 866895:HBHAL_RS03890
uniprot id: I0JJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

866895:HBHAL RS13080
gene id: 866895:HBHAL_RS13080
uniprot id: I0JPF3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

866895:HBHAL RS05985
gene id: 866895:HBHAL_RS05985
uniprot id: I0JK77
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

866895:HBHAL RS05505
gene id: 866895:HBHAL_RS05505
uniprot id: I0JJY2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

866895:HBHAL RS16685
gene id: 866895:HBHAL_RS16685
uniprot id: I0JRK3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

866895:HBHAL RS13645
gene id: 866895:HBHAL_RS13645
uniprot id: I0JPR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS00050
gene id: 866895:HBHAL_RS00050
uniprot id: I0JGX7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

866895:HBHAL RS06610
gene id: 866895:HBHAL_RS06610
uniprot id: I0JKK7
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS13020
gene id: 866895:HBHAL_RS13020
uniprot id: I0JPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

866895:HBHAL RS15030
gene id: 866895:HBHAL_RS15030
uniprot id: I0JQJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

866895:HBHAL RS12865
gene id: 866895:HBHAL_RS12865
uniprot id: I0JPB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

866895:HBHAL RS11560
gene id: 866895:HBHAL_RS11560
uniprot id: I0JNJ4
names: Similarity
messages: Belongs to the peptidase S49 family.

866895:HBHAL RS04230
gene id: 866895:HBHAL_RS04230
uniprot id: I0JJ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09235
gene id: 866895:HBHAL_RS09235
uniprot id: I0JM59
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

866895:HBHAL RS09050
gene id: 866895:HBHAL_RS09050
uniprot id: I0JM20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

866895:HBHAL RS02255
gene id: 866895:HBHAL_RS02255
uniprot id: I0JI25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

866895:HBHAL RS11370
gene id: 866895:HBHAL_RS11370
uniprot id: I0JNF5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS08300
gene id: 866895:HBHAL_RS08300
uniprot id: I0JLK7
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

866895:HBHAL RS00365
gene id: 866895:HBHAL_RS00365
uniprot id: I0JH34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

866895:HBHAL RS09180
gene id: 866895:HBHAL_RS09180
uniprot id: I0JM48
names: Similarity
messages: Belongs to the transpeptidase family.

866895:HBHAL RS11965
gene id: 866895:HBHAL_RS11965
uniprot id: I0JNT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

866895:HBHAL RS02965
gene id: 866895:HBHAL_RS02965
uniprot id: I0JIH5
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

866895:HBHAL RS00400
gene id: 866895:HBHAL_RS00400
uniprot id: I0JQV5
names: Similarity
messages: Belongs to the transposase 11 family.

866895:HBHAL RS15350
gene id: 866895:HBHAL_RS15350
uniprot id: I0JQR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

866895:HBHAL RS00660
gene id: 866895:HBHAL_RS00660
uniprot id: I0JH78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

866895:HBHAL RS18705
gene id: 866895:HBHAL_RS18705
uniprot id: I0JST4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

866895:HBHAL RS14670
gene id: 866895:HBHAL_RS14670
uniprot id: I0JQC6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

866895:HBHAL RS01390
gene id: 866895:HBHAL_RS01390
uniprot id: I0JHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS13535
gene id: 866895:HBHAL_RS13535
uniprot id: I0JPP2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

866895:HBHAL RS15520
gene id: 866895:HBHAL_RS15520
uniprot id: I0JQV2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

866895:HBHAL RS14000
gene id: 866895:HBHAL_RS14000
uniprot id: I0JPY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

866895:HBHAL RS04420
gene id: 866895:HBHAL_RS04420
uniprot id: I0JJD5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

866895:HBHAL RS04220
gene id: 866895:HBHAL_RS04220
uniprot id: I0JJ92
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11865
gene id: 866895:HBHAL_RS11865
uniprot id: I0JNQ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

866895:HBHAL RS17730
gene id: 866895:HBHAL_RS17730
uniprot id: I0JS82
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS09740
gene id: 866895:HBHAL_RS09740
uniprot id: I0JMG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS02020
gene id: 866895:HBHAL_RS02020
uniprot id: I0JHZ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS04325
gene id: 866895:HBHAL_RS04325
uniprot id: I0JJB5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS00100
gene id: 866895:HBHAL_RS00100
uniprot id: I0JGY6
names: Similarity
messages: Belongs to the DCK/DGK family.

866895:HBHAL RS16455
gene id: 866895:HBHAL_RS16455
uniprot id: I0JRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS05675
gene id: 866895:HBHAL_RS05675
uniprot id: I0JK15
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

866895:HBHAL RS09570
gene id: 866895:HBHAL_RS09570
uniprot id: I0JMC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

866895:HBHAL RS04235
gene id: 866895:HBHAL_RS04235
uniprot id: I0JJ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS05235
gene id: 866895:HBHAL_RS05235
uniprot id: I0JJU7
names: Similarity
messages: Belongs to the peptidase C40 family.

866895:HBHAL RS10160
gene id: 866895:HBHAL_RS10160
uniprot id: I0JMQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

866895:HBHAL RS13090
gene id: 866895:HBHAL_RS13090
uniprot id: I0JPF5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12605
gene id: 866895:HBHAL_RS12605
uniprot id: I0JP57
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

866895:HBHAL RS14825
gene id: 866895:HBHAL_RS14825
uniprot id: I0JQF5
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

866895:HBHAL RS08095
gene id: 866895:HBHAL_RS08095
uniprot id: I0JLG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS17455
gene id: 866895:HBHAL_RS17455
uniprot id: I0JS23
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

866895:HBHAL RS09615
gene id: 866895:HBHAL_RS09615
uniprot id: I0JME0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

866895:HBHAL RS19560
gene id: 866895:HBHAL_RS19560
uniprot id: I0JTA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS01420
gene id: 866895:HBHAL_RS01420
uniprot id: I0JHL8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS04595
gene id: 866895:HBHAL_RS04595
uniprot id: I0JJH0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS06125
gene id: 866895:HBHAL_RS06125
uniprot id: I0JKA5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS07215
gene id: 866895:HBHAL_RS07215
uniprot id: I0JKY6
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS04945
gene id: 866895:HBHAL_RS04945
uniprot id: I0JJN7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

866895:HBHAL RS08130
gene id: 866895:HBHAL_RS08130
uniprot id: I0JLH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

866895:HBHAL RS14565
gene id: 866895:HBHAL_RS14565
uniprot id: I0JQA5
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

866895:HBHAL RS08610
gene id: 866895:HBHAL_RS08610
uniprot id: I0JLS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

866895:HBHAL RS13580
gene id: 866895:HBHAL_RS13580
uniprot id: I0JPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

866895:HBHAL RS00205
gene id: 866895:HBHAL_RS00205
uniprot id: I0JH06
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

866895:HBHAL RS01035
gene id: 866895:HBHAL_RS01035
uniprot id: I0JHE0
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

866895:HBHAL RS05655
gene id: 866895:HBHAL_RS05655
uniprot id: I0JK11
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS08345
gene id: 866895:HBHAL_RS08345
uniprot id: I0JLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS02905
gene id: 866895:HBHAL_RS02905
uniprot id: I0JIG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS15675
gene id: 866895:HBHAL_RS15675
uniprot id: I0JQY4
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

866895:HBHAL RS06920
gene id: 866895:HBHAL_RS06920
uniprot id: I0JKS3
names: Similarity
messages: Belongs to the peptidase M20A family.

866895:HBHAL RS10880
gene id: 866895:HBHAL_RS10880
uniprot id: I0JN53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

866895:HBHAL RS06580
gene id: 866895:HBHAL_RS06580
uniprot id: I0JKK1
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

866895:HBHAL RS05910
gene id: 866895:HBHAL_RS05910
uniprot id: I0JK61
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS03045
gene id: 866895:HBHAL_RS03045
uniprot id: I0JIJ1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

866895:HBHAL RS12025
gene id: 866895:HBHAL_RS12025
uniprot id: I0JNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

866895:HBHAL RS19210
gene id: 866895:HBHAL_RS19210
uniprot id: I0JT37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

866895:HBHAL RS17410
gene id: 866895:HBHAL_RS17410
uniprot id: I0JS14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

866895:HBHAL RS08515
gene id: 866895:HBHAL_RS08515
uniprot id: I0JLQ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

866895:HBHAL RS01325
gene id: 866895:HBHAL_RS01325
uniprot id: I0JHJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

866895:HBHAL RS09910
gene id: 866895:HBHAL_RS09910
uniprot id: I0JMK0
names: Similarity
messages: Belongs to the DprA/Smf family.

866895:HBHAL RS08285
gene id: 866895:HBHAL_RS08285
uniprot id: I0JLK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS00785
gene id: 866895:HBHAL_RS00785
uniprot id: I0JHA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

866895:HBHAL RS19015
gene id: 866895:HBHAL_RS19015
uniprot id: I0JSZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

866895:HBHAL RS15125
gene id: 866895:HBHAL_RS15125
uniprot id: I0JQL9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

866895:HBHAL RS09835
gene id: 866895:HBHAL_RS09835
uniprot id: I0JMI5
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

866895:HBHAL RS10795
gene id: 866895:HBHAL_RS10795
uniprot id: I0JN35
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS12565
gene id: 866895:HBHAL_RS12565
uniprot id: I0JP49
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

866895:HBHAL RS06835
gene id: 866895:HBHAL_RS06835
uniprot id: I0JKQ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

866895:HBHAL RS09840
gene id: 866895:HBHAL_RS09840
uniprot id: I0JMI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

866895:HBHAL RS11655
gene id: 866895:HBHAL_RS11655
uniprot id: I0JNL2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

866895:HBHAL RS06840
gene id: 866895:HBHAL_RS06840
uniprot id: I0JKQ8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

866895:HBHAL RS11570
gene id: 866895:HBHAL_RS11570
uniprot id: I0JNJ6
names: Similarity
messages: Belongs to the cytochrome P450 family.

866895:HBHAL RS13430
gene id: 866895:HBHAL_RS13430
uniprot id: I0JPM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

866895:HBHAL RS18755
gene id: 866895:HBHAL_RS18755
uniprot id: I0JSU4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

866895:HBHAL RS00730
gene id: 866895:HBHAL_RS00730
uniprot id: I0JH92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

866895:HBHAL RS12895
gene id: 866895:HBHAL_RS12895
uniprot id: I0JPB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

866895:HBHAL RS09285
gene id: 866895:HBHAL_RS09285
uniprot id: I0JM71
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

866895:HBHAL RS19255
gene id: 866895:HBHAL_RS19255
uniprot id: I0JT48
names: Similarity
messages: Belongs to the glutamate synthase family.

866895:HBHAL RS14540
gene id: 866895:HBHAL_RS14540
uniprot id: I0JQA0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS10930
gene id: 866895:HBHAL_RS10930
uniprot id: I0JN64
names: Similarity
messages: Belongs to the UPF0398 family.

866895:HBHAL RS16885
gene id: 866895:HBHAL_RS16885
uniprot id: I0JRQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

866895:HBHAL RS12570
gene id: 866895:HBHAL_RS12570
uniprot id: I0JP50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

866895:HBHAL RS15765
gene id: 866895:HBHAL_RS15765
uniprot id: I0JR02
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

866895:HBHAL RS00340
gene id: 866895:HBHAL_RS00340
uniprot id: I0JH29
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

866895:HBHAL RS05065
gene id: 866895:HBHAL_RS05065
uniprot id: I0JJR5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

866895:HBHAL RS17360
gene id: 866895:HBHAL_RS17360
uniprot id: I0JS04
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

866895:HBHAL RS06975
gene id: 866895:HBHAL_RS06975
uniprot id: I0JKT4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS17935
gene id: 866895:HBHAL_RS17935
uniprot id: I0JSC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

866895:HBHAL RS03785
gene id: 866895:HBHAL_RS03785
uniprot id: I0JIZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS05850
gene id: 866895:HBHAL_RS05850
uniprot id: I0JK49
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

866895:HBHAL RS05010
gene id: 866895:HBHAL_RS05010
uniprot id: I0JJQ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS17440
gene id: 866895:HBHAL_RS17440
uniprot id: I0JS20
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS13445
gene id: 866895:HBHAL_RS13445
uniprot id: I0JPM4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

866895:HBHAL RS01715
gene id: 866895:HBHAL_RS01715
uniprot id: I0JHT5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

866895:HBHAL RS09750
gene id: 866895:HBHAL_RS09750
uniprot id: I0JMG9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS01485
gene id: 866895:HBHAL_RS01485
uniprot id: I0JHN4
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

866895:HBHAL RS02285
gene id: 866895:HBHAL_RS02285
uniprot id: I0JI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS07280
gene id: 866895:HBHAL_RS07280
uniprot id: I0JL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS17555
gene id: 866895:HBHAL_RS17555
uniprot id: I0JS47
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

866895:HBHAL RS00815
gene id: 866895:HBHAL_RS00815
uniprot id: I0JHA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

866895:HBHAL RS03080
gene id: 866895:HBHAL_RS03080
uniprot id: I0JIJ8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

866895:HBHAL RS07205
gene id: 866895:HBHAL_RS07205
uniprot id: I0JKY4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

866895:HBHAL RS03885
gene id: 866895:HBHAL_RS03885
uniprot id: I0JJ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

866895:HBHAL RS07140
gene id: 866895:HBHAL_RS07140
uniprot id: I0JKX1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12450
gene id: 866895:HBHAL_RS12450
uniprot id: I0JP23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

866895:HBHAL RS09355
gene id: 866895:HBHAL_RS09355
uniprot id: I0JM85
names: Similarity
messages: Belongs to the RemA family.

866895:HBHAL RS15475
gene id: 866895:HBHAL_RS15475
uniprot id: I0JQU2
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

866895:HBHAL RS09385
gene id: 866895:HBHAL_RS09385
uniprot id: I0JM91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

866895:HBHAL RS04700
gene id: 866895:HBHAL_RS04700
uniprot id: I0JJJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

866895:HBHAL RS13675
gene id: 866895:HBHAL_RS13675
uniprot id: I0JPS1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

866895:HBHAL RS08935
gene id: 866895:HBHAL_RS08935
uniprot id: I0JLZ6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

866895:HBHAL RS04785
gene id: 866895:HBHAL_RS04785
uniprot id: I0JJK7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

866895:HBHAL RS13115
gene id: 866895:HBHAL_RS13115
uniprot id: I0JPG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS01500
gene id: 866895:HBHAL_RS01500
uniprot id: I0JHN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

866895:HBHAL RS19095
gene id: 866895:HBHAL_RS19095
uniprot id: I0JT13
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

866895:HBHAL RS18345
gene id: 866895:HBHAL_RS18345
uniprot id: I0JSK6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

866895:HBHAL RS11495
gene id: 866895:HBHAL_RS11495
uniprot id: I0JNI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

866895:HBHAL RS11330
gene id: 866895:HBHAL_RS11330
uniprot id: I0JNE6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

866895:HBHAL RS18195
gene id: 866895:HBHAL_RS18195
uniprot id: I0JSH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

866895:HBHAL RS12765
gene id: 866895:HBHAL_RS12765
uniprot id: I0JP90
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

866895:HBHAL RS10500
gene id: 866895:HBHAL_RS10500
uniprot id: I0JMX4
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tlp family.
messages: Expressed only in the forespore compartment of sporulating cells.
messages: Spore core

866895:HBHAL RS01355
gene id: 866895:HBHAL_RS01355
uniprot id: I0JHK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

866895:HBHAL RS18785
gene id: 866895:HBHAL_RS18785
uniprot id: I0JSV1
names: Similarity
messages: Belongs to the CarB family.

866895:HBHAL RS10850
gene id: 866895:HBHAL_RS10850
uniprot id: I0JN46
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

866895:HBHAL RS09200
gene id: 866895:HBHAL_RS09200
uniprot id: I0JM52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS05635
gene id: 866895:HBHAL_RS05635
uniprot id: I0JK07
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

866895:HBHAL RS13460
gene id: 866895:HBHAL_RS13460
uniprot id: I0JPM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

866895:HBHAL RS13450
gene id: 866895:HBHAL_RS13450
uniprot id: I0JPM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

866895:HBHAL RS03090
gene id: 866895:HBHAL_RS03090
uniprot id: I0JIK0
names: Similarity
messages: Belongs to the GARS family.

866895:HBHAL RS01030
gene id: 866895:HBHAL_RS01030
uniprot id: I0JHD9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

866895:HBHAL RS02615
gene id: 866895:HBHAL_RS02615
uniprot id: I0JIA1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

866895:HBHAL RS03170
gene id: 866895:HBHAL_RS03170
uniprot id: I0JIL7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

866895:HBHAL RS19300
gene id: 866895:HBHAL_RS19300
uniprot id: I0JT56
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

866895:HBHAL RS19775
gene id: 866895:HBHAL_RS19775
uniprot id: I0JTF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS14815
gene id: 866895:HBHAL_RS14815
uniprot id: I0JQF3
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

866895:HBHAL RS08185
gene id: 866895:HBHAL_RS08185
uniprot id: I0JLI1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS13855
gene id: 866895:HBHAL_RS13855
uniprot id: I0JPV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS08480
gene id: 866895:HBHAL_RS08480
uniprot id: I0JLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

866895:HBHAL RS17535
gene id: 866895:HBHAL_RS17535
uniprot id: I0JS42
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

866895:HBHAL RS09335
gene id: 866895:HBHAL_RS09335
uniprot id: I0JM81
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS15525
gene id: 866895:HBHAL_RS15525
uniprot id: I0JQV3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

866895:HBHAL RS04205
gene id: 866895:HBHAL_RS04205
uniprot id: I0JJ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS19000
gene id: 866895:HBHAL_RS19000
uniprot id: I0JSZ5
names: Similarity
messages: Belongs to the asparagine synthetase family.

866895:HBHAL RS03755
gene id: 866895:HBHAL_RS03755
uniprot id: I0JIZ2
names: Similarity
messages: Belongs to the RutC family.

866895:HBHAL RS18710
gene id: 866895:HBHAL_RS18710
uniprot id: I0JST5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

866895:HBHAL RS10750
gene id: 866895:HBHAL_RS10750
uniprot id: I0JN26
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS19220
gene id: 866895:HBHAL_RS19220
uniprot id: I0JT40
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

866895:HBHAL RS17460
gene id: 866895:HBHAL_RS17460
uniprot id: I0JS24
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

866895:HBHAL RS00485
gene id: 866895:HBHAL_RS00485
uniprot id: I0JH57
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

866895:HBHAL RS03715
gene id: 866895:HBHAL_RS03715
uniprot id: I0JIY4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS15115
gene id: 866895:HBHAL_RS15115
uniprot id: I0JQL7
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS14225
gene id: 866895:HBHAL_RS14225
uniprot id: I0JQ36
names: Similarity
messages: Belongs to the HepT RNase toxin family.

866895:HBHAL RS07820
gene id: 866895:HBHAL_RS07820
uniprot id: I0JLA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

866895:HBHAL RS14970
gene id: 866895:HBHAL_RS14970
uniprot id: I0JQI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

866895:HBHAL RS15505
gene id: 866895:HBHAL_RS15505
uniprot id: I0JQU9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS09160
gene id: 866895:HBHAL_RS09160
uniprot id: I0JM44
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

866895:HBHAL RS03260
gene id: 866895:HBHAL_RS03260
uniprot id: I0JIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

866895:HBHAL RS17655
gene id: 866895:HBHAL_RS17655
uniprot id: I0JS67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

866895:HBHAL RS13110
gene id: 866895:HBHAL_RS13110
uniprot id: I0JPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09595
gene id: 866895:HBHAL_RS09595
uniprot id: I0JMD5
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

866895:HBHAL RS17810
gene id: 866895:HBHAL_RS17810
uniprot id: I0JS96
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

866895:HBHAL RS15500
gene id: 866895:HBHAL_RS15500
uniprot id: I0JQU8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

866895:HBHAL RS01290
gene id: 866895:HBHAL_RS01290
uniprot id: I0JHI9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS17805
gene id: 866895:HBHAL_RS17805
uniprot id: I0JS95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

866895:HBHAL RS00065
gene id: 866895:HBHAL_RS00065
uniprot id: I0JGY0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

866895:HBHAL RS04250
gene id: 866895:HBHAL_RS04250
uniprot id: I0JJ98
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

866895:HBHAL RS08190
gene id: 866895:HBHAL_RS08190
uniprot id: I0JLI2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

866895:HBHAL RS06665
gene id: 866895:HBHAL_RS06665
uniprot id: I0JKM2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

866895:HBHAL RS08895
gene id: 866895:HBHAL_RS08895
uniprot id: I0JLY6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

866895:HBHAL RS02185
gene id: 866895:HBHAL_RS02185
uniprot id: I0JI12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

866895:HBHAL RS04305
gene id: 866895:HBHAL_RS04305
uniprot id: I0JJB1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS01115
gene id: 866895:HBHAL_RS01115
uniprot id: I0JHF5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS03640
gene id: 866895:HBHAL_RS03640
uniprot id: I0JIW9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS03945
gene id: 866895:HBHAL_RS03945
uniprot id: I0JJ33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

866895:HBHAL RS01515
gene id: 866895:HBHAL_RS01515
uniprot id: I0JHP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

866895:HBHAL RS05120
gene id: 866895:HBHAL_RS05120
uniprot id: I0JJS5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

866895:HBHAL RS14285
gene id: 866895:HBHAL_RS14285
uniprot id: I0JQ49
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

866895:HBHAL RS14930
gene id: 866895:HBHAL_RS14930
uniprot id: I0JQH7
names: Similarity
messages: Belongs to the CapA family.

866895:HBHAL RS06440
gene id: 866895:HBHAL_RS06440
uniprot id: I0JKH2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

866895:HBHAL RS13105
gene id: 866895:HBHAL_RS13105
uniprot id: I0JPF8
names: Subcellular Location Annotation
messages: Cell membrane

866895:HBHAL RS00075
gene id: 866895:HBHAL_RS00075
uniprot id: I0JGY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

866895:HBHAL RS10545
gene id: 866895:HBHAL_RS10545
uniprot id: I0JMY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.
messages: Membrane

866895:HBHAL RS11105
gene id: 866895:HBHAL_RS11105
uniprot id: I0JNA1
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

866895:HBHAL RS17450
gene id: 866895:HBHAL_RS17450
uniprot id: I0JS22
names: Similarity
messages: Belongs to the peptidase S8 family.

866895:HBHAL RS13695
gene id: 866895:HBHAL_RS13695
uniprot id: I0JPS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

866895:HBHAL RS01165
gene id: 866895:HBHAL_RS01165
uniprot id: I0JHG5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS04295
gene id: 866895:HBHAL_RS04295
uniprot id: I0JJA7
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS02955
gene id: 866895:HBHAL_RS02955
uniprot id: I0JIH3
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS19800
gene id: 866895:HBHAL_RS19800
uniprot id: I0JTF7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

866895:HBHAL RS00715
gene id: 866895:HBHAL_RS00715
uniprot id: I0JH89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

866895:HBHAL RS15270
gene id: 866895:HBHAL_RS15270
uniprot id: I0JQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

866895:HBHAL RS00800
gene id: 866895:HBHAL_RS00800
uniprot id: I0JHA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

866895:HBHAL RS08735
gene id: 866895:HBHAL_RS08735
uniprot id: I0JLV2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS08810
gene id: 866895:HBHAL_RS08810
uniprot id: I0JLW9
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
messages: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.

866895:HBHAL RS11265
gene id: 866895:HBHAL_RS11265
uniprot id: I0JND4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

866895:HBHAL RS13570
gene id: 866895:HBHAL_RS13570
uniprot id: I0JPP9
names: Similarity
messages: Belongs to the UPF0173 family.

866895:HBHAL RS17425
gene id: 866895:HBHAL_RS17425
uniprot id: I0JS17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

866895:HBHAL RS02875
gene id: 866895:HBHAL_RS02875
uniprot id: I0JIF6
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS01410
gene id: 866895:HBHAL_RS01410
uniprot id: I0JHL4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS13945
gene id: 866895:HBHAL_RS13945
uniprot id: I0JPX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

866895:HBHAL RS09850
gene id: 866895:HBHAL_RS09850
uniprot id: I0JMI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

866895:HBHAL RS02705
gene id: 866895:HBHAL_RS02705
uniprot id: I0JIC1
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

866895:HBHAL RS01670
gene id: 866895:HBHAL_RS01670
uniprot id: I0JHS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

866895:HBHAL RS14900
gene id: 866895:HBHAL_RS14900
uniprot id: I0JQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

866895:HBHAL RS11905
gene id: 866895:HBHAL_RS11905
uniprot id: I0JNR8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

866895:HBHAL RS03165
gene id: 866895:HBHAL_RS03165
uniprot id: I0JIL6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

866895:HBHAL RS16530
gene id: 866895:HBHAL_RS16530
uniprot id: I0JRH2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

866895:HBHAL RS00885
gene id: 866895:HBHAL_RS00885
uniprot id: I0JHC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS15225
gene id: 866895:HBHAL_RS15225
uniprot id: I0JQN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

866895:HBHAL RS04680
gene id: 866895:HBHAL_RS04680
uniprot id: I0JJI7
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS00880
gene id: 866895:HBHAL_RS00880
uniprot id: I0JHC2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

866895:HBHAL RS02680
gene id: 866895:HBHAL_RS02680
uniprot id: I0JIB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

866895:HBHAL RS10105
gene id: 866895:HBHAL_RS10105
uniprot id: I0JMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

866895:HBHAL RS05240
gene id: 866895:HBHAL_RS05240
uniprot id: I0JJU8
names: Similarity
messages: Belongs to the gamma-type SASP family.

866895:HBHAL RS13765
gene id: 866895:HBHAL_RS13765
uniprot id: I0JPT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

866895:HBHAL RS10135
gene id: 866895:HBHAL_RS10135
uniprot id: I0JMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

866895:HBHAL RS14610
gene id: 866895:HBHAL_RS14610
uniprot id: I0JQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

866895:HBHAL RS13240
gene id: 866895:HBHAL_RS13240
uniprot id: I0JPH9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

866895:HBHAL RS17290
gene id: 866895:HBHAL_RS17290
uniprot id: I0JRZ0
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS00860
gene id: 866895:HBHAL_RS00860
uniprot id: I0JHB8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

866895:HBHAL RS17235
gene id: 866895:HBHAL_RS17235
uniprot id: I0JRX9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

866895:HBHAL RS20160
gene id: 866895:HBHAL_RS20160
uniprot id: I0JTM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

866895:HBHAL RS13725
gene id: 866895:HBHAL_RS13725
uniprot id: I0JPT1
names: Similarity
messages: Belongs to the histone deacetylase family.

866895:HBHAL RS12710
gene id: 866895:HBHAL_RS12710
uniprot id: I0JP79
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

866895:HBHAL RS10435
gene id: 866895:HBHAL_RS10435
uniprot id: I0JMV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

866895:HBHAL RS10420
gene id: 866895:HBHAL_RS10420
uniprot id: I0JMV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

866895:HBHAL RS16170
gene id: 866895:HBHAL_RS16170
uniprot id: I0JR90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

866895:HBHAL RS11500
gene id: 866895:HBHAL_RS11500
uniprot id: I0JNI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

866895:HBHAL RS12215
gene id: 866895:HBHAL_RS12215
uniprot id: I0JNY2
names: Similarity
messages: Belongs to the GSP E family.

866895:HBHAL RS09900
gene id: 866895:HBHAL_RS09900
uniprot id: I0JMJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

866895:HBHAL RS14060
gene id: 866895:HBHAL_RS14060
uniprot id: I0JQ01
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

866895:HBHAL RS14260
gene id: 866895:HBHAL_RS14260
uniprot id: I0JQ44
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS04715
gene id: 866895:HBHAL_RS04715
uniprot id: I0JJJ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

866895:HBHAL RS06805
gene id: 866895:HBHAL_RS06805
uniprot id: I0JKQ1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS08205
gene id: 866895:HBHAL_RS08205
uniprot id: I0JLI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

866895:HBHAL RS12720
gene id: 866895:HBHAL_RS12720
uniprot id: I0JP81
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

866895:HBHAL RS16195
gene id: 866895:HBHAL_RS16195
uniprot id: I0JR96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

866895:HBHAL RS12760
gene id: 866895:HBHAL_RS12760
uniprot id: I0JP89
names: Similarity
messages: Belongs to the UPF0297 family.

866895:HBHAL RS11120
gene id: 866895:HBHAL_RS11120
uniprot id: I0JNA4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS18455
gene id: 866895:HBHAL_RS18455
uniprot id: I0JSN0
names: Similarity
messages: Belongs to the peptidase M24B family.

866895:HBHAL RS02415
gene id: 866895:HBHAL_RS02415
uniprot id: I0JI56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

866895:HBHAL RS09185
gene id: 866895:HBHAL_RS09185
uniprot id: I0JM49
names: Similarity
messages: Belongs to the transpeptidase family.

866895:HBHAL RS04645
gene id: 866895:HBHAL_RS04645
uniprot id: I0JJI0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS19850
gene id: 866895:HBHAL_RS19850
uniprot id: I0JTG7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

866895:HBHAL RS15050
gene id: 866895:HBHAL_RS15050
uniprot id: I0JQK4
names: Similarity
messages: Belongs to the bacterial flagellin family.

866895:HBHAL RS04705
gene id: 866895:HBHAL_RS04705
uniprot id: I0JJJ2
names: Similarity
messages: Belongs to the manganese catalase family.

866895:HBHAL RS17510
gene id: 866895:HBHAL_RS17510
uniprot id: I0JS35
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

866895:HBHAL RS19950
gene id: 866895:HBHAL_RS19950
uniprot id: I0JTI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

866895:HBHAL RS18155
gene id: 866895:HBHAL_RS18155
uniprot id: I0JSG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

866895:HBHAL RS06895
gene id: 866895:HBHAL_RS06895
uniprot id: I0JKR8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS05705
gene id: 866895:HBHAL_RS05705
uniprot id: I0JK21
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS09220
gene id: 866895:HBHAL_RS09220
uniprot id: I0JM56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

866895:HBHAL RS17420
gene id: 866895:HBHAL_RS17420
uniprot id: I0JS16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

866895:HBHAL RS17820
gene id: 866895:HBHAL_RS17820
uniprot id: I0JS98
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

866895:HBHAL RS17840
gene id: 866895:HBHAL_RS17840
uniprot id: I0JSA3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

866895:HBHAL RS12185
gene id: 866895:HBHAL_RS12185
uniprot id: I0JNX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

866895:HBHAL RS19885
gene id: 866895:HBHAL_RS19885
uniprot id: I0JTH6
names: Similarity
messages: Belongs to the threonine aldolase family.

866895:HBHAL RS10640
gene id: 866895:HBHAL_RS10640
uniprot id: I0JN03
names: Similarity
messages: Belongs to the nitroreductase family.

866895:HBHAL RS11945
gene id: 866895:HBHAL_RS11945
uniprot id: I0JNS8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

866895:HBHAL RS03060
gene id: 866895:HBHAL_RS03060
uniprot id: I0JIJ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

866895:HBHAL RS10175
gene id: 866895:HBHAL_RS10175
uniprot id: I0JMQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

866895:HBHAL RS14790
gene id: 866895:HBHAL_RS14790
uniprot id: I0JQE8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

866895:HBHAL RS12645
gene id: 866895:HBHAL_RS12645
uniprot id: I0JP65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

866895:HBHAL RS09100
gene id: 866895:HBHAL_RS09100
uniprot id: I0JM31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

866895:HBHAL RS06865
gene id: 866895:HBHAL_RS06865
uniprot id: I0JKR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

866895:HBHAL RS01875
gene id: 866895:HBHAL_RS01875
uniprot id: I0JHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS08560
gene id: 866895:HBHAL_RS08560
uniprot id: I0JLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS19290
gene id: 866895:HBHAL_RS19290
uniprot id: I0JT54
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

866895:HBHAL RS12770
gene id: 866895:HBHAL_RS12770
uniprot id: I0JP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

866895:HBHAL RS00835
gene id: 866895:HBHAL_RS00835
uniprot id: I0JHB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

866895:HBHAL RS15040
gene id: 866895:HBHAL_RS15040
uniprot id: I0JQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

866895:HBHAL RS17795
gene id: 866895:HBHAL_RS17795
uniprot id: I0JS94
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

866895:HBHAL RS12730
gene id: 866895:HBHAL_RS12730
uniprot id: I0JP83
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

866895:HBHAL RS11470
gene id: 866895:HBHAL_RS11470
uniprot id: I0JNH5
names: Similarity
messages: Belongs to the sigma-70 factor family.

866895:HBHAL RS09250
gene id: 866895:HBHAL_RS09250
uniprot id: I0JM63
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

866895:HBHAL RS13600
gene id: 866895:HBHAL_RS13600
uniprot id: I0JPQ5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS00845
gene id: 866895:HBHAL_RS00845
uniprot id: I0JHB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

866895:HBHAL RS04600
gene id: 866895:HBHAL_RS04600
uniprot id: I0JJH1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS05765
gene id: 866895:HBHAL_RS05765
uniprot id: I0JK33
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS12075
gene id: 866895:HBHAL_RS12075
uniprot id: I0JNV4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

866895:HBHAL RS02180
gene id: 866895:HBHAL_RS02180
uniprot id: I0JI11
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

866895:HBHAL RS18220
gene id: 866895:HBHAL_RS18220
uniprot id: I0JSH8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

866895:HBHAL RS02215
gene id: 866895:HBHAL_RS02215
uniprot id: I0JI18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

866895:HBHAL RS14955
gene id: 866895:HBHAL_RS14955
uniprot id: I0JQI4
names: Similarity
messages: Belongs to the peptidase S41A family.

866895:HBHAL RS09470
gene id: 866895:HBHAL_RS09470
uniprot id: I0JMA8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

866895:HBHAL RS15090
gene id: 866895:HBHAL_RS15090
uniprot id: I0JQL2
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS13175
gene id: 866895:HBHAL_RS13175
uniprot id: I0JPH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09805
gene id: 866895:HBHAL_RS09805
uniprot id: I0JMH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

866895:HBHAL RS12320
gene id: 866895:HBHAL_RS12320
uniprot id: I0JP04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

866895:HBHAL RS11860
gene id: 866895:HBHAL_RS11860
uniprot id: I0JNQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

866895:HBHAL RS09945
gene id: 866895:HBHAL_RS09945
uniprot id: I0JMK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

866895:HBHAL RS11825
gene id: 866895:HBHAL_RS11825
uniprot id: I0JNQ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

866895:HBHAL RS06850
gene id: 866895:HBHAL_RS06850
uniprot id: I0JKR0
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

866895:HBHAL RS13345
gene id: 866895:HBHAL_RS13345
uniprot id: I0JPK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

866895:HBHAL RS13620
gene id: 866895:HBHAL_RS13620
uniprot id: I0JPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

866895:HBHAL RS01815
gene id: 866895:HBHAL_RS01815
uniprot id: I0JHV5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS10675
gene id: 866895:HBHAL_RS10675
uniprot id: I0JN11
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

866895:HBHAL RS10740
gene id: 866895:HBHAL_RS10740
uniprot id: I0JN24
names: Similarity
messages: Belongs to the peptidase S58 family.

866895:HBHAL RS19835
gene id: 866895:HBHAL_RS19835
uniprot id: I0JTG4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11135
gene id: 866895:HBHAL_RS11135
uniprot id: I0JNA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

866895:HBHAL RS15480
gene id: 866895:HBHAL_RS15480
uniprot id: I0JQU3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

866895:HBHAL RS16645
gene id: 866895:HBHAL_RS16645
uniprot id: I0JRJ5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

866895:HBHAL RS00780
gene id: 866895:HBHAL_RS00780
uniprot id: I0JHA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

866895:HBHAL RS13305
gene id: 866895:HBHAL_RS13305
uniprot id: I0JPJ3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

866895:HBHAL RS17110
gene id: 866895:HBHAL_RS17110
uniprot id: I0JRV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS00770
gene id: 866895:HBHAL_RS00770
uniprot id: I0JHA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

866895:HBHAL RS14850
gene id: 866895:HBHAL_RS14850
uniprot id: I0JQG0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates/dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

866895:HBHAL RS00905
gene id: 866895:HBHAL_RS00905
uniprot id: I0JHC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

866895:HBHAL RS18110
gene id: 866895:HBHAL_RS18110
uniprot id: I0JSF5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

866895:HBHAL RS00910
gene id: 866895:HBHAL_RS00910
uniprot id: I0JHC8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

866895:HBHAL RS04390
gene id: 866895:HBHAL_RS04390
uniprot id: I0JJC9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

866895:HBHAL RS06015
gene id: 866895:HBHAL_RS06015
uniprot id: I0JK83
names: Similarity
messages: Belongs to the GbsR family.

866895:HBHAL RS16985
gene id: 866895:HBHAL_RS16985
uniprot id: I0JRS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS06000
gene id: 866895:HBHAL_RS06000
uniprot id: I0JK80
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12340
gene id: 866895:HBHAL_RS12340
uniprot id: I0JP08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

866895:HBHAL RS20030
gene id: 866895:HBHAL_RS20030
uniprot id: I0JTK3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS12490
gene id: 866895:HBHAL_RS12490
uniprot id: I0JP34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

866895:HBHAL RS07115
gene id: 866895:HBHAL_RS07115
uniprot id: I0JKW4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

866895:HBHAL RS11480
gene id: 866895:HBHAL_RS11480
uniprot id: I0JNH7
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

866895:HBHAL RS10120
gene id: 866895:HBHAL_RS10120
uniprot id: I0JMP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

866895:HBHAL RS08485
gene id: 866895:HBHAL_RS08485
uniprot id: I0JLP6
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

866895:HBHAL RS14665
gene id: 866895:HBHAL_RS14665
uniprot id: I0JQC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

866895:HBHAL RS01305
gene id: 866895:HBHAL_RS01305
uniprot id: I0JHJ1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

866895:HBHAL RS13370
gene id: 866895:HBHAL_RS13370
uniprot id: I0JPK7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

866895:HBHAL RS01385
gene id: 866895:HBHAL_RS01385
uniprot id: I0JHK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

866895:HBHAL RS08710
gene id: 866895:HBHAL_RS08710
uniprot id: I0JLU5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS19810
gene id: 866895:HBHAL_RS19810
uniprot id: I0JTF9
names: Similarity
messages: Belongs to the CdaR family.

866895:HBHAL RS18555
gene id: 866895:HBHAL_RS18555
uniprot id: I0JSQ2
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS09020
gene id: 866895:HBHAL_RS09020
uniprot id: I0JM14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

866895:HBHAL RS08680
gene id: 866895:HBHAL_RS08680
uniprot id: I0JLT9
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

866895:HBHAL RS16165
gene id: 866895:HBHAL_RS16165
uniprot id: I0JR89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

866895:HBHAL RS19985
gene id: 866895:HBHAL_RS19985
uniprot id: I0JTJ6
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

866895:HBHAL RS01160
gene id: 866895:HBHAL_RS01160
uniprot id: I0JHG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

866895:HBHAL RS11250
gene id: 866895:HBHAL_RS11250
uniprot id: I0JND0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

866895:HBHAL RS01200
gene id: 866895:HBHAL_RS01200
uniprot id: I0JHH1
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

866895:HBHAL RS05200
gene id: 866895:HBHAL_RS05200
uniprot id: I0JJU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

866895:HBHAL RS08240
gene id: 866895:HBHAL_RS08240
uniprot id: I0JLJ3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

866895:HBHAL RS15610
gene id: 866895:HBHAL_RS15610
uniprot id: I0JQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

866895:HBHAL RS09960
gene id: 866895:HBHAL_RS09960
uniprot id: I0JML0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

866895:HBHAL RS16960
gene id: 866895:HBHAL_RS16960
uniprot id: I0JRS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

866895:HBHAL RS03705
gene id: 866895:HBHAL_RS03705
uniprot id: I0JIY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

866895:HBHAL RS02780
gene id: 866895:HBHAL_RS02780
uniprot id: I0JID8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS10530
gene id: 866895:HBHAL_RS10530
uniprot id: I0JMY0
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

866895:HBHAL RS16900
gene id: 866895:HBHAL_RS16900
uniprot id: I0JRQ4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS17065
gene id: 866895:HBHAL_RS17065
uniprot id: I0JRU5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

866895:HBHAL RS05915
gene id: 866895:HBHAL_RS05915
uniprot id: I0JK62
names: Similarity
messages: Belongs to the WrbA family.

866895:HBHAL RS05560
gene id: 866895:HBHAL_RS05560
uniprot id: I0JJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS09875
gene id: 866895:HBHAL_RS09875
uniprot id: I0JMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS02195
gene id: 866895:HBHAL_RS02195
uniprot id: I0JI14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

866895:HBHAL RS03035
gene id: 866895:HBHAL_RS03035
uniprot id: I0JII9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

866895:HBHAL RS17435
gene id: 866895:HBHAL_RS17435
uniprot id: I0JS19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

866895:HBHAL RS12800
gene id: 866895:HBHAL_RS12800
uniprot id: I0JP96
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS07925
gene id: 866895:HBHAL_RS07925
uniprot id: I0JLC8
names: Similarity
messages: Belongs to the FBPase class 3 family.

866895:HBHAL RS19260
gene id: 866895:HBHAL_RS19260
uniprot id: I0JT49
names: Similarity
messages: Belongs to the peptidase S58 family.

866895:HBHAL RS06575
gene id: 866895:HBHAL_RS06575
uniprot id: I0JKK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

866895:HBHAL RS12680
gene id: 866895:HBHAL_RS12680
uniprot id: I0JP73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS07275
gene id: 866895:HBHAL_RS07275
uniprot id: I0JKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS08070
gene id: 866895:HBHAL_RS08070
uniprot id: I0JLF9
names: Similarity
messages: Belongs to the UPF0047 family.

866895:HBHAL RS12455
gene id: 866895:HBHAL_RS12455
uniprot id: I0JP24
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

866895:HBHAL RS16610
gene id: 866895:HBHAL_RS16610
uniprot id: I0JRI8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS10915
gene id: 866895:HBHAL_RS10915
uniprot id: I0JN61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

866895:HBHAL RS15700
gene id: 866895:HBHAL_RS15700
uniprot id: I0JQY9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

866895:HBHAL RS07885
gene id: 866895:HBHAL_RS07885
uniprot id: I0JLC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS14915
gene id: 866895:HBHAL_RS14915
uniprot id: I0JQH4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS20295
gene id: 866895:HBHAL_RS20295
uniprot id: I0JTP7
names: Similarity
messages: Belongs to the Gram-positive plasmids replication protein type 1 family.

866895:HBHAL RS07125
gene id: 866895:HBHAL_RS07125
uniprot id: I0JKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS00765
gene id: 866895:HBHAL_RS00765
uniprot id: I0JH99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

866895:HBHAL RS03385
gene id: 866895:HBHAL_RS03385
uniprot id: I0JIR4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS00870
gene id: 866895:HBHAL_RS00870
uniprot id: I0JHC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

866895:HBHAL RS07750
gene id: 866895:HBHAL_RS07750
uniprot id: I0JL88
names: Similarity
messages: Belongs to the EamA transporter family.

866895:HBHAL RS01145
gene id: 866895:HBHAL_RS01145
uniprot id: I0JHG1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

866895:HBHAL RS09295
gene id: 866895:HBHAL_RS09295
uniprot id: I0JM73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

866895:HBHAL RS15535
gene id: 866895:HBHAL_RS15535
uniprot id: I0JQV5
names: Similarity
messages: Belongs to the transposase 11 family.

866895:HBHAL RS13285
gene id: 866895:HBHAL_RS13285
uniprot id: I0JPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

866895:HBHAL RS10145
gene id: 866895:HBHAL_RS10145
uniprot id: I0JMQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

866895:HBHAL RS14655
gene id: 866895:HBHAL_RS14655
uniprot id: I0JQC3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

866895:HBHAL RS00150
gene id: 866895:HBHAL_RS00150
uniprot id: I0JGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

866895:HBHAL RS08840
gene id: 866895:HBHAL_RS08840
uniprot id: I0JLX5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS05195
gene id: 866895:HBHAL_RS05195
uniprot id: I0JJT9
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS17635
gene id: 866895:HBHAL_RS17635
uniprot id: I0JS63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

866895:HBHAL RS02010
gene id: 866895:HBHAL_RS02010
uniprot id: I0JHZ4
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12560
gene id: 866895:HBHAL_RS12560
uniprot id: I0JP48
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

866895:HBHAL RS14230
gene id: 866895:HBHAL_RS14230
uniprot id: I0JQ37
names: Similarity
messages: Belongs to the FBPase class 2 family.

866895:HBHAL RS18145
gene id: 866895:HBHAL_RS18145
uniprot id: I0JSG2
names: Subcellular Location Annotation
messages: Cell membrane

866895:HBHAL RS19415
gene id: 866895:HBHAL_RS19415
uniprot id: I0JT78
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS13985
gene id: 866895:HBHAL_RS13985
uniprot id: I0JPY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

866895:HBHAL RS16625
gene id: 866895:HBHAL_RS16625
uniprot id: I0JRJ1
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

866895:HBHAL RS00760
gene id: 866895:HBHAL_RS00760
uniprot id: I0JH98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

866895:HBHAL RS18470
gene id: 866895:HBHAL_RS18470
uniprot id: I0JSN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

866895:HBHAL RS00085
gene id: 866895:HBHAL_RS00085
uniprot id: I0JGY4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS18500
gene id: 866895:HBHAL_RS18500
uniprot id: I0JSN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

866895:HBHAL RS13075
gene id: 866895:HBHAL_RS13075
uniprot id: I0JPF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

866895:HBHAL RS12300
gene id: 866895:HBHAL_RS12300
uniprot id: I0JNZ8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS19460
gene id: 866895:HBHAL_RS19460
uniprot id: I0JT86
names: Similarity
messages: Belongs to the ABC transporter superfamily.

866895:HBHAL RS19450
gene id: 866895:HBHAL_RS19450
uniprot id: I0JT84
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS14590
gene id: 866895:HBHAL_RS14590
uniprot id: I0JQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

866895:HBHAL RS00310
gene id: 866895:HBHAL_RS00310
uniprot id: I0JH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

866895:HBHAL RS04300
gene id: 866895:HBHAL_RS04300
uniprot id: I0JJA8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12750
gene id: 866895:HBHAL_RS12750
uniprot id: I0JP87
names: Similarity
messages: Belongs to the UPF0473 family.

866895:HBHAL RS06450
gene id: 866895:HBHAL_RS06450
uniprot id: I0JKH5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

866895:HBHAL RS10045
gene id: 866895:HBHAL_RS10045
uniprot id: I0JMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

866895:HBHAL RS02550
gene id: 866895:HBHAL_RS02550
uniprot id: I0JI86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

866895:HBHAL RS05480
gene id: 866895:HBHAL_RS05480
uniprot id: I0JJX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

866895:HBHAL RS08530
gene id: 866895:HBHAL_RS08530
uniprot id: I0JLQ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

866895:HBHAL RS18315
gene id: 866895:HBHAL_RS18315
uniprot id: I0JSJ9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

866895:HBHAL RS09715
gene id: 866895:HBHAL_RS09715
uniprot id: I0JMG1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

866895:HBHAL RS03905
gene id: 866895:HBHAL_RS03905
uniprot id: I0JJ25
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

866895:HBHAL RS03115
gene id: 866895:HBHAL_RS03115
uniprot id: I0JIK5
names: Similarity
messages: Belongs to the threonine synthase family.

866895:HBHAL RS04455
gene id: 866895:HBHAL_RS04455
uniprot id: I0JJE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS05750
gene id: 866895:HBHAL_RS05750
uniprot id: I0JK30
names: Subunit
messages: Homodimer.

866895:HBHAL RS11020
gene id: 866895:HBHAL_RS11020
uniprot id: I0JN84
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

866895:HBHAL RS09815
gene id: 866895:HBHAL_RS09815
uniprot id: I0JMI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

866895:HBHAL RS12700
gene id: 866895:HBHAL_RS12700
uniprot id: I0JP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS02555
gene id: 866895:HBHAL_RS02555
uniprot id: I0JI87
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

866895:HBHAL RS14510
gene id: 866895:HBHAL_RS14510
uniprot id: I0JQ94
names: Similarity
messages: Belongs to the malate synthase family.

866895:HBHAL RS05535
gene id: 866895:HBHAL_RS05535
uniprot id: I0JJY8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

866895:HBHAL RS17095
gene id: 866895:HBHAL_RS17095
uniprot id: I0JRV1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

866895:HBHAL RS19295
gene id: 866895:HBHAL_RS19295
uniprot id: I0JT55
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

866895:HBHAL RS09925
gene id: 866895:HBHAL_RS09925
uniprot id: I0JMK3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

866895:HBHAL RS06430
gene id: 866895:HBHAL_RS06430
uniprot id: I0JKG9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS10505
gene id: 866895:HBHAL_RS10505
uniprot id: I0JMX5
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

866895:HBHAL RS11270
gene id: 866895:HBHAL_RS11270
uniprot id: I0JND5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

866895:HBHAL RS18225
gene id: 866895:HBHAL_RS18225
uniprot id: I0JSH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS09175
gene id: 866895:HBHAL_RS09175
uniprot id: I0JM47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

866895:HBHAL RS09165
gene id: 866895:HBHAL_RS09165
uniprot id: I0JM45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

866895:HBHAL RS02320
gene id: 866895:HBHAL_RS02320
uniprot id: I0JI36
names: Similarity
messages: Belongs to the polysaccharide synthase family.

866895:HBHAL RS00665
gene id: 866895:HBHAL_RS00665
uniprot id: I0JH79
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

866895:HBHAL RS05525
gene id: 866895:HBHAL_RS05525
uniprot id: I0JJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

866895:HBHAL RS13255
gene id: 866895:HBHAL_RS13255
uniprot id: I0JPI2
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS03685
gene id: 866895:HBHAL_RS03685
uniprot id: I0JIX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

866895:HBHAL RS16340
gene id: 866895:HBHAL_RS16340
uniprot id: I0JRC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

866895:HBHAL RS05460
gene id: 866895:HBHAL_RS05460
uniprot id: I0JJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

866895:HBHAL RS18800
gene id: 866895:HBHAL_RS18800
uniprot id: I0JSV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

866895:HBHAL RS03970
gene id: 866895:HBHAL_RS03970
uniprot id: I0JJ39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

866895:HBHAL RS16555
gene id: 866895:HBHAL_RS16555
uniprot id: I0JRH7
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS07160
gene id: 866895:HBHAL_RS07160
uniprot id: I0JKX5
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS07795
gene id: 866895:HBHAL_RS07795
uniprot id: I0JL96
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

866895:HBHAL RS16275
gene id: 866895:HBHAL_RS16275
uniprot id: I0JRB2
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS08060
gene id: 866895:HBHAL_RS08060
uniprot id: I0JLF7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

866895:HBHAL RS19895
gene id: 866895:HBHAL_RS19895
uniprot id: I0JTH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS03200
gene id: 866895:HBHAL_RS03200
uniprot id: I0JIM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

866895:HBHAL RS16975
gene id: 866895:HBHAL_RS16975
uniprot id: I0JRS4
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

866895:HBHAL RS11190
gene id: 866895:HBHAL_RS11190
uniprot id: I0JNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

866895:HBHAL RS06165
gene id: 866895:HBHAL_RS06165
uniprot id: I0JKB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

866895:HBHAL RS12430
gene id: 866895:HBHAL_RS12430
uniprot id: I0JP20
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

866895:HBHAL RS08690
gene id: 866895:HBHAL_RS08690
uniprot id: I0JLU1
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

866895:HBHAL RS10940
gene id: 866895:HBHAL_RS10940
uniprot id: I0JN66
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

866895:HBHAL RS08305
gene id: 866895:HBHAL_RS08305
uniprot id: I0JLK8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

866895:HBHAL RS17080
gene id: 866895:HBHAL_RS17080
uniprot id: I0JRU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

866895:HBHAL RS08990
gene id: 866895:HBHAL_RS08990
uniprot id: I0JM07
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

866895:HBHAL RS07890
gene id: 866895:HBHAL_RS07890
uniprot id: I0JLC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS15160
gene id: 866895:HBHAL_RS15160
uniprot id: I0JQM5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

866895:HBHAL RS09420
gene id: 866895:HBHAL_RS09420
uniprot id: I0JM98
names: Similarity
messages: Belongs to the asp23 family.

866895:HBHAL RS18965
gene id: 866895:HBHAL_RS18965
uniprot id: I0JSY8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

866895:HBHAL RS10805
gene id: 866895:HBHAL_RS10805
uniprot id: I0JN37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

866895:HBHAL RS06460
gene id: 866895:HBHAL_RS06460
uniprot id: I0JKH7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

866895:HBHAL RS15680
gene id: 866895:HBHAL_RS15680
uniprot id: I0JQY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

866895:HBHAL RS00820
gene id: 866895:HBHAL_RS00820
uniprot id: I0JHB0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

866895:HBHAL RS13500
gene id: 866895:HBHAL_RS13500
uniprot id: I0JPN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

866895:HBHAL RS04815
gene id: 866895:HBHAL_RS04815
uniprot id: I0JJL3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

866895:HBHAL RS13520
gene id: 866895:HBHAL_RS13520
uniprot id: I0JPN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

866895:HBHAL RS08820
gene id: 866895:HBHAL_RS08820
uniprot id: I0JLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

866895:HBHAL RS12315
gene id: 866895:HBHAL_RS12315
uniprot id: I0JP02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

866895:HBHAL RS19135
gene id: 866895:HBHAL_RS19135
uniprot id: I0JT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

866895:HBHAL RS18235
gene id: 866895:HBHAL_RS18235
uniprot id: I0JSI1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS18340
gene id: 866895:HBHAL_RS18340
uniprot id: I0JSK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

866895:HBHAL RS10710
gene id: 866895:HBHAL_RS10710
uniprot id: I0JN18
names: Subcellular Location Annotation
messages: Cytoplasm

866895:HBHAL RS15210
gene id: 866895:HBHAL_RS15210
uniprot id: I0JQN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS15315
gene id: 866895:HBHAL_RS15315
uniprot id: I0JQQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Cytoplasm
messages: Gas vesicle
messages: Vesicle

866895:HBHAL RS03490
gene id: 866895:HBHAL_RS03490
uniprot id: I0JIT8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS00020
gene id: 866895:HBHAL_RS00020
uniprot id: I0JGX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

866895:HBHAL RS11385
gene id: 866895:HBHAL_RS11385
uniprot id: I0JNF8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

866895:HBHAL RS07500
gene id: 866895:HBHAL_RS07500
uniprot id: I0JL38
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11085
gene id: 866895:HBHAL_RS11085
uniprot id: I0JN97
names: Similarity
messages: Belongs to the UPF0302 family.

866895:HBHAL RS18160
gene id: 866895:HBHAL_RS18160
uniprot id: I0JSG6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS03595
gene id: 866895:HBHAL_RS03595
uniprot id: I0JIW0
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

866895:HBHAL RS15400
gene id: 866895:HBHAL_RS15400
uniprot id: I0JQS3
names: Similarity
messages: Belongs to the UPF0312 family.

866895:HBHAL RS02980
gene id: 866895:HBHAL_RS02980
uniprot id: I0JIH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fosfomycin resistance protein family. FosB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.

866895:HBHAL RS05665
gene id: 866895:HBHAL_RS05665
uniprot id: I0JK13
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS12280
gene id: 866895:HBHAL_RS12280
uniprot id: I0JNZ4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

866895:HBHAL RS12355
gene id: 866895:HBHAL_RS12355
uniprot id: I0JP11
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

866895:HBHAL RS06655
gene id: 866895:HBHAL_RS06655
uniprot id: I0JKL9
names: Subcellular Location Annotation
messages: Cell membrane

866895:HBHAL RS02005
gene id: 866895:HBHAL_RS02005
uniprot id: I0JHZ3
names: Similarity
messages: Belongs to the DEAD box helicase family.

866895:HBHAL RS10195
gene id: 866895:HBHAL_RS10195
uniprot id: I0JMQ9
names: Similarity
messages: Belongs to the ribF family.

866895:HBHAL RS12010
gene id: 866895:HBHAL_RS12010
uniprot id: I0JNU0
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

866895:HBHAL RS12655
gene id: 866895:HBHAL_RS12655
uniprot id: I0JP67
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

866895:HBHAL RS13950
gene id: 866895:HBHAL_RS13950
uniprot id: I0JPX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS09315
gene id: 866895:HBHAL_RS09315
uniprot id: I0JM77
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS12225
gene id: 866895:HBHAL_RS12225
uniprot id: I0JNY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

866895:HBHAL RS14760
gene id: 866895:HBHAL_RS14760
uniprot id: I0JQE3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

866895:HBHAL RS15240
gene id: 866895:HBHAL_RS15240
uniprot id: D9ZZC7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

866895:HBHAL RS04435
gene id: 866895:HBHAL_RS04435
uniprot id: I0JJD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

866895:HBHAL RS12815
gene id: 866895:HBHAL_RS12815
uniprot id: I0JP99
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

866895:HBHAL RS08260
gene id: 866895:HBHAL_RS08260
uniprot id: I0JLJ7
names: Similarity
messages: Belongs to the peptidase C40 family.

866895:HBHAL RS09975
gene id: 866895:HBHAL_RS09975
uniprot id: I0JML3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS13575
gene id: 866895:HBHAL_RS13575
uniprot id: I0JPQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS00900
gene id: 866895:HBHAL_RS00900
uniprot id: I0JHC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS19115
gene id: 866895:HBHAL_RS19115
uniprot id: I0JT17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS11230
gene id: 866895:HBHAL_RS11230
uniprot id: I0JNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

866895:HBHAL RS00160
gene id: 866895:HBHAL_RS00160
uniprot id: I0JGZ7
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS09130
gene id: 866895:HBHAL_RS09130
uniprot id: I0JM38
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

866895:HBHAL RS05885
gene id: 866895:HBHAL_RS05885
uniprot id: I0JK56
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS17230
gene id: 866895:HBHAL_RS17230
uniprot id: I0JRX8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

866895:HBHAL RS02590
gene id: 866895:HBHAL_RS02590
uniprot id: I0JI96
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11110
gene id: 866895:HBHAL_RS11110
uniprot id: I0JNA2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

866895:HBHAL RS13590
gene id: 866895:HBHAL_RS13590
uniprot id: I0JPQ3
names: Similarity
messages: Belongs to the PspA/IM30 family.

866895:HBHAL RS19975
gene id: 866895:HBHAL_RS19975
uniprot id: I0JTJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

866895:HBHAL RS19860
gene id: 866895:HBHAL_RS19860
uniprot id: I0JTG9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

866895:HBHAL RS05160
gene id: 866895:HBHAL_RS05160
uniprot id: I0JJT3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

866895:HBHAL RS09555
gene id: 866895:HBHAL_RS09555
uniprot id: I0JMC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

866895:HBHAL RS06915
gene id: 866895:HBHAL_RS06915
uniprot id: I0JKS2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

866895:HBHAL RS09210
gene id: 866895:HBHAL_RS09210
uniprot id: I0JM54
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS20015
gene id: 866895:HBHAL_RS20015
uniprot id: I0JTK0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS19365
gene id: 866895:HBHAL_RS19365
uniprot id: I0JT68
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

866895:HBHAL RS17650
gene id: 866895:HBHAL_RS17650
uniprot id: I0JS66
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

866895:HBHAL RS03040
gene id: 866895:HBHAL_RS03040
uniprot id: I0JIJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

866895:HBHAL RS16995
gene id: 866895:HBHAL_RS16995
uniprot id: I0JRT0
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

866895:HBHAL RS04510
gene id: 866895:HBHAL_RS04510
uniprot id: I0JJF2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

866895:HBHAL RS09370
gene id: 866895:HBHAL_RS09370
uniprot id: I0JM88
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS14975
gene id: 866895:HBHAL_RS14975
uniprot id: I0JQI8
names: PTM
messages: Binds 1 heme c group covalently per subunit.

866895:HBHAL RS10900
gene id: 866895:HBHAL_RS10900
uniprot id: I0JN58
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

866895:HBHAL RS19600
gene id: 866895:HBHAL_RS19600
uniprot id: I0JTB8
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS11345
gene id: 866895:HBHAL_RS11345
uniprot id: I0JNE9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

866895:HBHAL RS12880
gene id: 866895:HBHAL_RS12880
uniprot id: I0JPB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS07800
gene id: 866895:HBHAL_RS07800
uniprot id: I0JL97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

866895:HBHAL RS09575
gene id: 866895:HBHAL_RS09575
uniprot id: I0JMD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

866895:HBHAL RS06545
gene id: 866895:HBHAL_RS06545
uniprot id: I0JKJ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
messages: Homodimer.
messages: The N-terminal domain has binding sites for ComK and probably for unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

866895:HBHAL RS18175
gene id: 866895:HBHAL_RS18175
uniprot id: I0JSG9
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS17615
gene id: 866895:HBHAL_RS17615
uniprot id: I0JS59
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

866895:HBHAL RS00385
gene id: 866895:HBHAL_RS00385
uniprot id: I0JH38
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS09505
gene id: 866895:HBHAL_RS09505
uniprot id: I0JMB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

866895:HBHAL RS14205
gene id: 866895:HBHAL_RS14205
uniprot id: I0JQ32
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

866895:HBHAL RS19305
gene id: 866895:HBHAL_RS19305
uniprot id: I0JT57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

866895:HBHAL RS09755
gene id: 866895:HBHAL_RS09755
uniprot id: I0JMH0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

866895:HBHAL RS13130
gene id: 866895:HBHAL_RS13130
uniprot id: I0JPG3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

866895:HBHAL RS12125
gene id: 866895:HBHAL_RS12125
uniprot id: I0JNW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

866895:HBHAL RS09885
gene id: 866895:HBHAL_RS09885
uniprot id: I0JMJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

866895:HBHAL RS14080
gene id: 866895:HBHAL_RS14080
uniprot id: I0JQ05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

866895:HBHAL RS17220
gene id: 866895:HBHAL_RS17220
uniprot id: I0JRX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS20120
gene id: 866895:HBHAL_RS20120
uniprot id: I0JTM1
names: Subcellular Location Annotation
messages: Membrane

866895:HBHAL RS10315
gene id: 866895:HBHAL_RS10315
uniprot id: I0JMT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

866895:HBHAL RS06715
gene id: 866895:HBHAL_RS06715
uniprot id: I0JKN4
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

866895:HBHAL RS12625
gene id: 866895:HBHAL_RS12625
uniprot id: I0JP61
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

866895:HBHAL RS08675
gene id: 866895:HBHAL_RS08675
uniprot id: I0JLT8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

866895:HBHAL RS18830
gene id: 866895:HBHAL_RS18830
uniprot id: I0JSW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GerABKA family.
messages: Cell membrane
messages: Membrane

866895:HBHAL RS00890
gene id: 866895:HBHAL_RS00890
uniprot id: I0JHC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

866895:HBHAL RS12900
gene id: 866895:HBHAL_RS12900
uniprot id: I0JPB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).