861109:SIDU RS16895
gene id: 861109:SIDU_RS16895
uniprot id: A0A1L5BT07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

861109:SIDU RS16220
gene id: 861109:SIDU_RS16220
uniprot id: A0A1L5BSN0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS08155
gene id: 861109:SIDU_RS08155
uniprot id: A0A1L5BTV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

861109:SIDU RS17160
gene id: 861109:SIDU_RS17160
uniprot id: A0A1L5BT40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

861109:SIDU RS00660
gene id: 861109:SIDU_RS00660
uniprot id: I5BAQ9
names: Similarity
messages: Belongs to the UPF0102 family.

861109:SIDU RS03025
gene id: 861109:SIDU_RS03025
uniprot id: I5BFX3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

861109:SIDU RS08125
gene id: 861109:SIDU_RS08125
uniprot id: A0A1L5BNU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

861109:SIDU RS13380
gene id: 861109:SIDU_RS13380
uniprot id: A0A1L5BR95
names: Similarity
messages: Belongs to the ArsC family.

861109:SIDU RS03105
gene id: 861109:SIDU_RS03105
uniprot id: A0A1L5BKY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

861109:SIDU RS10110
gene id: 861109:SIDU_RS10110
uniprot id: A0A1L5BPH7
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS12875
gene id: 861109:SIDU_RS12875
uniprot id: A0A1L5BQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

861109:SIDU RS02940
gene id: 861109:SIDU_RS02940
uniprot id: A0A1L5BL05
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

861109:SIDU RS16480
gene id: 861109:SIDU_RS16480
uniprot id: A0A1L5BSS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

861109:SIDU RS09685
gene id: 861109:SIDU_RS09685
uniprot id: A0A1L5BPD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

861109:SIDU RS11900
gene id: 861109:SIDU_RS11900
uniprot id: A0A1L5BQQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS04505
gene id: 861109:SIDU_RS04505
uniprot id: A0A1L5BLR7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

861109:SIDU RS10330
gene id: 861109:SIDU_RS10330
uniprot id: A0A1L5BPX4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

861109:SIDU RS12710
gene id: 861109:SIDU_RS12710
uniprot id: A0A1L5BQW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

861109:SIDU RS06630
gene id: 861109:SIDU_RS06630
uniprot id: A0A1L5BN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

861109:SIDU RS11555
gene id: 861109:SIDU_RS11555
uniprot id: P59767
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HCH dehydrochlorinase family.
messages: Catalyzes the conversion of the important environmental pollutant gamma-hexachlorocyclohexane (gamma-HCH or lindane) to 1,3,4,6-tetrachloro-1,4-cyclohexadiene (1,4-TCDN) via gamma-pentachlorocyclohexene (gamma-PCCH) (PubMed:12450824). Proceeds by two successive 1,2-anti conformationally dependent dehydrochlorinations (By similarity). Also shows activity with alpha- and delta-HCH, giving alpha- and delta-PCCH respectively, but not with the beta isomer (PubMed:12450824).
messages: Gamma-hexachlorocyclohexane (lindane) is an organochlorine insecticide which has been used worldwide since the 1940s. Because of its toxicity and long persistence in soil, most countries have prohibited the use of gamma-HCH. However, many contaminated sites still remain throughout the world.
messages: Homotrimer.
messages: Is not N-terminally processed during export, so it may be secreted into the periplasmic space via a hitherto unknown mechanism.
messages: Periplasm

861109:SIDU RS07195
gene id: 861109:SIDU_RS07195
uniprot id: A0A1L5BND6
names: Similarity
messages: Belongs to the asparagine synthetase family.

861109:SIDU RS12290
gene id: 861109:SIDU_RS12290
uniprot id: A0A1L5BQL6
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

861109:SIDU RS08030
gene id: 861109:SIDU_RS08030
uniprot id: A0A1L5BTV8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

861109:SIDU RS02355
gene id: 861109:SIDU_RS02355
uniprot id: A0A1L5BKJ6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

861109:SIDU RS13610
gene id: 861109:SIDU_RS13610
uniprot id: A0A1L5BU32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

861109:SIDU RS17455
gene id: 861109:SIDU_RS17455
uniprot id: A0A1L5BTA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS00435
gene id: 861109:SIDU_RS00435
uniprot id: A0A1L5BK06
names: Similarity
messages: Belongs to the UPF0434 family.

861109:SIDU RS17545
gene id: 861109:SIDU_RS17545
uniprot id: A0A1L5BTB2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

861109:SIDU RS13355
gene id: 861109:SIDU_RS13355
uniprot id: A0A1L5BR55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS14890
gene id: 861109:SIDU_RS14890
uniprot id: A0A1L5BRW9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

861109:SIDU RS17360
gene id: 861109:SIDU_RS17360
uniprot id: A0A1L5BT98
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS09085
gene id: 861109:SIDU_RS09085
uniprot id: A0A1L5BP17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

861109:SIDU RS01620
gene id: 861109:SIDU_RS01620
uniprot id: A0A1L5BKD4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

861109:SIDU RS15345
gene id: 861109:SIDU_RS15345
uniprot id: A0A1L5BU58
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

861109:SIDU RS00890
gene id: 861109:SIDU_RS00890
uniprot id: A0A1L5BK19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS08700
gene id: 861109:SIDU_RS08700
uniprot id: A0A1L5BNW0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS18035
gene id: 861109:SIDU_RS18035
uniprot id: A0A1L5BUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS06895
gene id: 861109:SIDU_RS06895
uniprot id: A0A1L5BMV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS11535
gene id: 861109:SIDU_RS11535
uniprot id: A0A1L5BUG3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS05330
gene id: 861109:SIDU_RS05330
uniprot id: I5BDT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

861109:SIDU RS12585
gene id: 861109:SIDU_RS12585
uniprot id: A0A1L5BU20
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

861109:SIDU RS00655
gene id: 861109:SIDU_RS00655
uniprot id: I5BDW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

861109:SIDU RS00460
gene id: 861109:SIDU_RS00460
uniprot id: A0A1L5BJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

861109:SIDU RS17195
gene id: 861109:SIDU_RS17195
uniprot id: A0A1L5BT77
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS12510
gene id: 861109:SIDU_RS12510
uniprot id: A0A1L5BQP8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

861109:SIDU RS09855
gene id: 861109:SIDU_RS09855
uniprot id: A0A1L5BPF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS16050
gene id: 861109:SIDU_RS16050
uniprot id: A0A1L5BSI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS04480
gene id: 861109:SIDU_RS04480
uniprot id: A0A1L5BLW1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

861109:SIDU RS07820
gene id: 861109:SIDU_RS07820
uniprot id: A0A1L5BNB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

861109:SIDU RS14920
gene id: 861109:SIDU_RS14920
uniprot id: A0A1L5BS88
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

861109:SIDU RS12730
gene id: 861109:SIDU_RS12730
uniprot id: A0A1L5BQW3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

861109:SIDU RS10350
gene id: 861109:SIDU_RS10350
uniprot id: A0A1L5BQ11
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

861109:SIDU RS03075
gene id: 861109:SIDU_RS03075
uniprot id: A0A1L5BL17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

861109:SIDU RS10670
gene id: 861109:SIDU_RS10670
uniprot id: A0A1L5BPV9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

861109:SIDU RS08080
gene id: 861109:SIDU_RS08080
uniprot id: A0A1L5BNG3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS14105
gene id: 861109:SIDU_RS14105
uniprot id: A0A1L5BRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

861109:SIDU RS01045
gene id: 861109:SIDU_RS01045
uniprot id: A0A1L5BK04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

861109:SIDU RS04420
gene id: 861109:SIDU_RS04420
uniprot id: A0A1L5BLV2
names: Similarity
messages: Belongs to the YkuD family.

861109:SIDU RS08040
gene id: 861109:SIDU_RS08040
uniprot id: A0A1L5BNI0
names: Subcellular Location Annotation
messages: Cell outer membrane

861109:SIDU RS01575
gene id: 861109:SIDU_RS01575
uniprot id: A0A1L5BKL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

861109:SIDU RS04510
gene id: 861109:SIDU_RS04510
uniprot id: A0A1L5BLS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

861109:SIDU RS07460
gene id: 861109:SIDU_RS07460
uniprot id: A0A1L5BN19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

861109:SIDU RS04400
gene id: 861109:SIDU_RS04400
uniprot id: A0A1L5BLP8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

861109:SIDU RS05055
gene id: 861109:SIDU_RS05055
uniprot id: A0A1L5BMA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

861109:SIDU RS04025
gene id: 861109:SIDU_RS04025
uniprot id: A0A1L5BLN5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

861109:SIDU RS00665
gene id: 861109:SIDU_RS00665
uniprot id: I5BAR0
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

861109:SIDU RS18590
gene id: 861109:SIDU_RS18590
uniprot id: A0A1L5BUS4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

861109:SIDU RS00115
gene id: 861109:SIDU_RS00115
uniprot id: A0A1L5BJV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

861109:SIDU RS10595
gene id: 861109:SIDU_RS10595
uniprot id: A0A1L5BPR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS10825
gene id: 861109:SIDU_RS10825
uniprot id: A0A1L5BTY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

861109:SIDU RS03185
gene id: 861109:SIDU_RS03185
uniprot id: A0A1L5BL09
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

861109:SIDU RS10780
gene id: 861109:SIDU_RS10780
uniprot id: A0A1L5BQ53
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

861109:SIDU RS03835
gene id: 861109:SIDU_RS03835
uniprot id: A0A1L5BLB1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

861109:SIDU RS00895
gene id: 861109:SIDU_RS00895
uniprot id: A0A1L5BJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

861109:SIDU RS15125
gene id: 861109:SIDU_RS15125
uniprot id: I5BB99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

861109:SIDU RS13680
gene id: 861109:SIDU_RS13680
uniprot id: A0A1L5BRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

861109:SIDU RS02650
gene id: 861109:SIDU_RS02650
uniprot id: A0A1L5BKQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

861109:SIDU RS07915
gene id: 861109:SIDU_RS07915
uniprot id: A0A1L5BNA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

861109:SIDU RS05515
gene id: 861109:SIDU_RS05515
uniprot id: A0A1L5BMI7
names: Similarity
messages: Belongs to the MreC family.

861109:SIDU RS00495
gene id: 861109:SIDU_RS00495
uniprot id: A0A1L5BK15
names: Similarity
messages: Belongs to the peptidase S41A family.

861109:SIDU RS17285
gene id: 861109:SIDU_RS17285
uniprot id: A0A1L5BT79
names: Similarity
messages: Belongs to the peptidase M24B family.

861109:SIDU RS08680
gene id: 861109:SIDU_RS08680
uniprot id: A0A1L5BP44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

861109:SIDU RS08485
gene id: 861109:SIDU_RS08485
uniprot id: A0A1L5BNX5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS04875
gene id: 861109:SIDU_RS04875
uniprot id: A0A1L5BLX6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS07105
gene id: 861109:SIDU_RS07105
uniprot id: A0A1L5BN33
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

861109:SIDU RS05895
gene id: 861109:SIDU_RS05895
uniprot id: A0A1L5BMC3
names: Similarity
messages: Belongs to the DprA/Smf family.

861109:SIDU RS08710
gene id: 861109:SIDU_RS08710
uniprot id: A0A1L5BP12
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

861109:SIDU RS04490
gene id: 861109:SIDU_RS04490
uniprot id: A0A1L5BLK9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

861109:SIDU RS01105
gene id: 861109:SIDU_RS01105
uniprot id: A0A1L5BK86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

861109:SIDU RS06945
gene id: 861109:SIDU_RS06945
uniprot id: A0A1L5BMS0
names: Similarity
messages: Belongs to the pirin family.

861109:SIDU RS07985
gene id: 861109:SIDU_RS07985
uniprot id: A0A1L5BND5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

861109:SIDU RS04720
gene id: 861109:SIDU_RS04720
uniprot id: A0A1L5BM36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

861109:SIDU RS01905
gene id: 861109:SIDU_RS01905
uniprot id: A0A1L5BKH6
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS10160
gene id: 861109:SIDU_RS10160
uniprot id: A0A1L5BPI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

861109:SIDU RS13280
gene id: 861109:SIDU_RS13280
uniprot id: A0A1L5BRD9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS13670
gene id: 861109:SIDU_RS13670
uniprot id: A0A1L5BRC8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

861109:SIDU RS05175
gene id: 861109:SIDU_RS05175
uniprot id: A0A1L5BMC2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

861109:SIDU RS00790
gene id: 861109:SIDU_RS00790
uniprot id: A0A1L5BJV2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

861109:SIDU RS13850
gene id: 861109:SIDU_RS13850
uniprot id: A0A1L5BRD8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

861109:SIDU RS05720
gene id: 861109:SIDU_RS05720
uniprot id: A0A1L5BME8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

861109:SIDU RS10465
gene id: 861109:SIDU_RS10465
uniprot id: A0A1L5BQ31
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS05190
gene id: 861109:SIDU_RS05190
uniprot id: A0A1L5BLZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

861109:SIDU RS06990
gene id: 861109:SIDU_RS06990
uniprot id: A0A1L5BN77
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

861109:SIDU RS14100
gene id: 861109:SIDU_RS14100
uniprot id: A0A1L5BRJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

861109:SIDU RS01540
gene id: 861109:SIDU_RS01540
uniprot id: A0A1L5BKH4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS00500
gene id: 861109:SIDU_RS00500
uniprot id: A0A1L5BK21
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS08020
gene id: 861109:SIDU_RS08020
uniprot id: A0A1L5BNJ4
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

861109:SIDU RS10620
gene id: 861109:SIDU_RS10620
uniprot id: A0A1L5BPP8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

861109:SIDU RS04390
gene id: 861109:SIDU_RS04390
uniprot id: A0A1L5BLX8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

861109:SIDU RS16485
gene id: 861109:SIDU_RS16485
uniprot id: A0A1L5BST0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

861109:SIDU RS07795
gene id: 861109:SIDU_RS07795
uniprot id: A0A1L5BND8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

861109:SIDU RS19040
gene id: 861109:SIDU_RS19040
uniprot id: A0A1L5BMR0
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

861109:SIDU RS06010
gene id: 861109:SIDU_RS06010
uniprot id: A0A1L5BTS2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

861109:SIDU RS15455
gene id: 861109:SIDU_RS15455
uniprot id: A0A1L5BU66
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

861109:SIDU RS13555
gene id: 861109:SIDU_RS13555
uniprot id: A0A1L5BRI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

861109:SIDU RS10760
gene id: 861109:SIDU_RS10760
uniprot id: A0A1L5BPU1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

861109:SIDU RS14785
gene id: 861109:SIDU_RS14785
uniprot id: A0A1L5BRW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

861109:SIDU RS15630
gene id: 861109:SIDU_RS15630
uniprot id: A0A1L5BSL1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

861109:SIDU RS16570
gene id: 861109:SIDU_RS16570
uniprot id: A0A1L5BST9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

861109:SIDU RS12315
gene id: 861109:SIDU_RS12315
uniprot id: A0A1L5BQU8
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

861109:SIDU RS13760
gene id: 861109:SIDU_RS13760
uniprot id: A0A1L5BRK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

861109:SIDU RS00125
gene id: 861109:SIDU_RS00125
uniprot id: A0A1L5BJK5
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

861109:SIDU RS17375
gene id: 861109:SIDU_RS17375
uniprot id: A0A1L5BT91
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS10530
gene id: 861109:SIDU_RS10530
uniprot id: A0A1L5BQ40
names: Similarity
messages: Belongs to the UPF0235 family.

861109:SIDU RS02135
gene id: 861109:SIDU_RS02135
uniprot id: A0A1L5BKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

861109:SIDU RS05095
gene id: 861109:SIDU_RS05095
uniprot id: A0A1L5BM61
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

861109:SIDU RS16475
gene id: 861109:SIDU_RS16475
uniprot id: A0A1L5BT08
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861109:SIDU RS01150
gene id: 861109:SIDU_RS01150
uniprot id: I5BGE3
names: Similarity
messages: Belongs to the YkuD family.

861109:SIDU RS06705
gene id: 861109:SIDU_RS06705
uniprot id: A0A1L5BN29
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS05265
gene id: 861109:SIDU_RS05265
uniprot id: A0A1L5BLZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

861109:SIDU RS07855
gene id: 861109:SIDU_RS07855
uniprot id: A0A1L5BNB7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS08590
gene id: 861109:SIDU_RS08590
uniprot id: A0A1L5BNQ2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

861109:SIDU RS10555
gene id: 861109:SIDU_RS10555
uniprot id: A0A1L5BQ37
names: Similarity
messages: Belongs to the threonine synthase family.

861109:SIDU RS06440
gene id: 861109:SIDU_RS06440
uniprot id: A0A1L5BMZ8
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS18185
gene id: 861109:SIDU_RS18185
uniprot id: A0A1L5BU05
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the degradation of 2,5-dichloro-2,5-cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ) in vitro. LinX appears not to be involved in gamma-hexachlorocyclohexane (gamma-HCH) degradation pathway, in contrast to LinC which has the same enzymatic activity.

861109:SIDU RS06795
gene id: 861109:SIDU_RS06795
uniprot id: A0A1L5BMX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

861109:SIDU RS05845
gene id: 861109:SIDU_RS05845
uniprot id: A0A1L5BMG4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

861109:SIDU RS17135
gene id: 861109:SIDU_RS17135
uniprot id: A0A1L5BT23
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

861109:SIDU RS02840
gene id: 861109:SIDU_RS02840
uniprot id: A0A1L5BKX4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

861109:SIDU RS16510
gene id: 861109:SIDU_RS16510
uniprot id: A0A1L5BSU6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

861109:SIDU RS11955
gene id: 861109:SIDU_RS11955
uniprot id: A0A1L5BQR2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

861109:SIDU RS13005
gene id: 861109:SIDU_RS13005
uniprot id: A0A1L5BR12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

861109:SIDU RS04195
gene id: 861109:SIDU_RS04195
uniprot id: A0A1L5BLU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

861109:SIDU RS07965
gene id: 861109:SIDU_RS07965
uniprot id: A0A1L5BNP0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

861109:SIDU RS09780
gene id: 861109:SIDU_RS09780
uniprot id: A0A1L5BPF6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

861109:SIDU RS13575
gene id: 861109:SIDU_RS13575
uniprot id: A0A1L5BR93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

861109:SIDU RS07790
gene id: 861109:SIDU_RS07790
uniprot id: A0A1L5BNK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

861109:SIDU RS12050
gene id: 861109:SIDU_RS12050
uniprot id: A0A1L5BQF8
names: Similarity
messages: Belongs to the CobH/CbiC family.

861109:SIDU RS16715
gene id: 861109:SIDU_RS16715
uniprot id: A0A1L5BT30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

861109:SIDU RS02425
gene id: 861109:SIDU_RS02425
uniprot id: A0A1L5BKL8
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

861109:SIDU RS14965
gene id: 861109:SIDU_RS14965
uniprot id: A0A1L5BS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

861109:SIDU RS06545
gene id: 861109:SIDU_RS06545
uniprot id: A0A1L5BN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

861109:SIDU RS13885
gene id: 861109:SIDU_RS13885
uniprot id: A0A1L5BRM7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

861109:SIDU RS15325
gene id: 861109:SIDU_RS15325
uniprot id: A0A1L5BS65
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

861109:SIDU RS11735
gene id: 861109:SIDU_RS11735
uniprot id: A0A1L5BQD2
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

861109:SIDU RS01280
gene id: 861109:SIDU_RS01280
uniprot id: A0A1L5BK43
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

861109:SIDU RS10840
gene id: 861109:SIDU_RS10840
uniprot id: A0A1L5BPY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

861109:SIDU RS05940
gene id: 861109:SIDU_RS05940
uniprot id: A0A1L5BM88
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

861109:SIDU RS11070
gene id: 861109:SIDU_RS11070
uniprot id: A0A1L5BPZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS08550
gene id: 861109:SIDU_RS08550
uniprot id: A0A1L5BP08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

861109:SIDU RS12205
gene id: 861109:SIDU_RS12205
uniprot id: A0A1L5BQJ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS05700
gene id: 861109:SIDU_RS05700
uniprot id: A0A1L5BTX2
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

861109:SIDU RS08615
gene id: 861109:SIDU_RS08615
uniprot id: A0A1L5BNS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

861109:SIDU RS02495
gene id: 861109:SIDU_RS02495
uniprot id: A0A1L5BTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS05350
gene id: 861109:SIDU_RS05350
uniprot id: I5BET5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

861109:SIDU RS18065
gene id: 861109:SIDU_RS18065
uniprot id: A0A1L5BUK0
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

861109:SIDU RS12955
gene id: 861109:SIDU_RS12955
uniprot id: A0A1L5BQX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

861109:SIDU RS13840
gene id: 861109:SIDU_RS13840
uniprot id: A0A1L5BRH7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

861109:SIDU RS06655
gene id: 861109:SIDU_RS06655
uniprot id: A0A1L5BN39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

861109:SIDU RS00810
gene id: 861109:SIDU_RS00810
uniprot id: A0A1L5BJW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

861109:SIDU RS04965
gene id: 861109:SIDU_RS04965
uniprot id: A0A1L5BM97
names: Similarity
messages: Belongs to the DEAD box helicase family.

861109:SIDU RS02825
gene id: 861109:SIDU_RS02825
uniprot id: A0A1L5BTJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

861109:SIDU RS09720
gene id: 861109:SIDU_RS09720
uniprot id: A0A1L5BPA9
names: Similarity
messages: Belongs to the CFA/CMAS family.

861109:SIDU RS07635
gene id: 861109:SIDU_RS07635
uniprot id: A0A1L5BNL5
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

861109:SIDU RS06675
gene id: 861109:SIDU_RS06675
uniprot id: A0A1L5BMR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

861109:SIDU RS04795
gene id: 861109:SIDU_RS04795
uniprot id: A0A1L5BLR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

861109:SIDU RS02700
gene id: 861109:SIDU_RS02700
uniprot id: A0A1L5BKQ9
names: Similarity
messages: Belongs to the aspartokinase family.

861109:SIDU RS08640
gene id: 861109:SIDU_RS08640
uniprot id: A0A1L5BNR2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS09280
gene id: 861109:SIDU_RS09280
uniprot id: A0A1L5BP77
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

861109:SIDU RS09885
gene id: 861109:SIDU_RS09885
uniprot id: A0A1L5BPD6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

861109:SIDU RS11600
gene id: 861109:SIDU_RS11600
uniprot id: A0A1L5BQ71
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS04635
gene id: 861109:SIDU_RS04635
uniprot id: A0A1L5BLT7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

861109:SIDU RS12405
gene id: 861109:SIDU_RS12405
uniprot id: A0A1L5BQN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

861109:SIDU RS07380
gene id: 861109:SIDU_RS07380
uniprot id: A0A1L5BN41
names: Similarity
messages: Belongs to the SAICAR synthetase family.

861109:SIDU RS15550
gene id: 861109:SIDU_RS15550
uniprot id: A0A1L5BSI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

861109:SIDU RS01760
gene id: 861109:SIDU_RS01760
uniprot id: A0A1L5BKB6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

861109:SIDU RS05840
gene id: 861109:SIDU_RS05840
uniprot id: A0A1L5BMP7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

861109:SIDU RS12820
gene id: 861109:SIDU_RS12820
uniprot id: A0A1L5BQW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

861109:SIDU RS06860
gene id: 861109:SIDU_RS06860
uniprot id: A0A1L5BMV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

861109:SIDU RS12775
gene id: 861109:SIDU_RS12775
uniprot id: A0A1L5BR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

861109:SIDU RS05255
gene id: 861109:SIDU_RS05255
uniprot id: A0A1L5BM79
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861109:SIDU RS06885
gene id: 861109:SIDU_RS06885
uniprot id: A0A1L5BMX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

861109:SIDU RS07235
gene id: 861109:SIDU_RS07235
uniprot id: A0A1L5BN34
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS13170
gene id: 861109:SIDU_RS13170
uniprot id: A0A1L5BU27
names: Similarity
messages: Belongs to the AlaDH/PNT family.

861109:SIDU RS07190
gene id: 861109:SIDU_RS07190
uniprot id: A0A1L5BN01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

861109:SIDU RS08975
gene id: 861109:SIDU_RS08975
uniprot id: A0A1L5BP64
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS12765
gene id: 861109:SIDU_RS12765
uniprot id: A0A1L5BQV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

861109:SIDU RS10340
gene id: 861109:SIDU_RS10340
uniprot id: A0A1L5BPJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

861109:SIDU RS00955
gene id: 861109:SIDU_RS00955
uniprot id: A0A1L5BTG9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

861109:SIDU RS13320
gene id: 861109:SIDU_RS13320
uniprot id: A0A1L5BRC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

861109:SIDU RS11785
gene id: 861109:SIDU_RS11785
uniprot id: I5B918
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

861109:SIDU RS04110
gene id: 861109:SIDU_RS04110
uniprot id: A0A1L5BTN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

861109:SIDU RS18260
gene id: 861109:SIDU_RS18260
uniprot id: I5BCJ6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

861109:SIDU RS07925
gene id: 861109:SIDU_RS07925
uniprot id: A0A1L5BNR3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

861109:SIDU RS15090
gene id: 861109:SIDU_RS15090
uniprot id: I5BEK3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS03130
gene id: 861109:SIDU_RS03130
uniprot id: A0A1L5BKZ9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

861109:SIDU RS06940
gene id: 861109:SIDU_RS06940
uniprot id: A0A1L5BMY7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS11355
gene id: 861109:SIDU_RS11355
uniprot id: A0A1L5BQ72
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

861109:SIDU RS04580
gene id: 861109:SIDU_RS04580
uniprot id: A0A1L5BLP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS14700
gene id: 861109:SIDU_RS14700
uniprot id: A0A1L5BRT8
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

861109:SIDU RS01285
gene id: 861109:SIDU_RS01285
uniprot id: A0A1L5BK90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

861109:SIDU RS12190
gene id: 861109:SIDU_RS12190
uniprot id: A0A1L5BU18
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

861109:SIDU RS14395
gene id: 861109:SIDU_RS14395
uniprot id: A0A1L5BRY3
names: Similarity
messages: Belongs to the glutamate synthase family.

861109:SIDU RS17205
gene id: 861109:SIDU_RS17205
uniprot id: A0A1L5BT67
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS18105
gene id: 861109:SIDU_RS18105
uniprot id: A0A1L5BUF5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

861109:SIDU RS05880
gene id: 861109:SIDU_RS05880
uniprot id: A0A1L5BTQ9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

861109:SIDU RS06325
gene id: 861109:SIDU_RS06325
uniprot id: I5B8Q1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS06735
gene id: 861109:SIDU_RS06735
uniprot id: A0A1L5BMS1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

861109:SIDU RS00825
gene id: 861109:SIDU_RS00825
uniprot id: A0A1L5BK10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

861109:SIDU RS15500
gene id: 861109:SIDU_RS15500
uniprot id: A0A1L5BSH8
names: Similarity
messages: Belongs to the BolA/IbaG family.

861109:SIDU RS08365
gene id: 861109:SIDU_RS08365
uniprot id: A0A1L5BNK7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS04755
gene id: 861109:SIDU_RS04755
uniprot id: A0A1L5BM37
names: Similarity
messages: Belongs to the Gfa family.

861109:SIDU RS04640
gene id: 861109:SIDU_RS04640
uniprot id: A0A1L5BLU5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861109:SIDU RS03380
gene id: 861109:SIDU_RS03380
uniprot id: A0A1L5BL41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

861109:SIDU RS00275
gene id: 861109:SIDU_RS00275
uniprot id: A0A1L5BJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

861109:SIDU RS04685
gene id: 861109:SIDU_RS04685
uniprot id: A0A1L5BLP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS07670
gene id: 861109:SIDU_RS07670
uniprot id: I5BHL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS06030
gene id: 861109:SIDU_RS06030
uniprot id: A0A1L5BME5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

861109:SIDU RS04600
gene id: 861109:SIDU_RS04600
uniprot id: A0A1L5BM13
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

861109:SIDU RS03970
gene id: 861109:SIDU_RS03970
uniprot id: A0A1L5BLQ1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

861109:SIDU RS10790
gene id: 861109:SIDU_RS10790
uniprot id: A0A1L5BPT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

861109:SIDU RS16555
gene id: 861109:SIDU_RS16555
uniprot id: A0A1L5BSZ9
names: Similarity
messages: Belongs to the SufE family.

861109:SIDU RS03865
gene id: 861109:SIDU_RS03865
uniprot id: A0A1L5BTL8
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

861109:SIDU RS15490
gene id: 861109:SIDU_RS15490
uniprot id: A0A1L5BS94
names: Similarity
messages: Belongs to the pirin family.

861109:SIDU RS00770
gene id: 861109:SIDU_RS00770
uniprot id: A0A1L5BJV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

861109:SIDU RS12385
gene id: 861109:SIDU_RS12385
uniprot id: A0A1L5BQY3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

861109:SIDU RS04270
gene id: 861109:SIDU_RS04270
uniprot id: A0A1L5BLH5
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS16315
gene id: 861109:SIDU_RS16315
uniprot id: A0A1L5BSN9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

861109:SIDU RS14860
gene id: 861109:SIDU_RS14860
uniprot id: A0A1L5BRY6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS10265
gene id: 861109:SIDU_RS10265
uniprot id: A0A1L5BPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

861109:SIDU RS12905
gene id: 861109:SIDU_RS12905
uniprot id: A0A1L5BR01
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

861109:SIDU RS09505
gene id: 861109:SIDU_RS09505
uniprot id: A0A1L5BPK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

861109:SIDU RS17745
gene id: 861109:SIDU_RS17745
uniprot id: A0A1L5BU92
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

861109:SIDU RS18050
gene id: 861109:SIDU_RS18050
uniprot id: A0A1L5BUG1
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS09095
gene id: 861109:SIDU_RS09095
uniprot id: A0A1L5BNY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

861109:SIDU RS10755
gene id: 861109:SIDU_RS10755
uniprot id: A0A1L5BPX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

861109:SIDU RS01985
gene id: 861109:SIDU_RS01985
uniprot id: A0A1L5BKQ4
names: Similarity
messages: Belongs to the glutamate synthase family.

861109:SIDU RS16635
gene id: 861109:SIDU_RS16635
uniprot id: A0A1L5BT32
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

861109:SIDU RS14150
gene id: 861109:SIDU_RS14150
uniprot id: A0A1L5BRK4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

861109:SIDU RS09655
gene id: 861109:SIDU_RS09655
uniprot id: A0A1L5BP91
names: Similarity
messages: Belongs to the MlaA family.

861109:SIDU RS10545
gene id: 861109:SIDU_RS10545
uniprot id: A0A1L5BPQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS12945
gene id: 861109:SIDU_RS12945
uniprot id: A0A1L5BQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

861109:SIDU RS10765
gene id: 861109:SIDU_RS10765
uniprot id: A0A1L5BPU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

861109:SIDU RS03065
gene id: 861109:SIDU_RS03065
uniprot id: A0A1L5BL93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

861109:SIDU RS12065
gene id: 861109:SIDU_RS12065
uniprot id: A0A1L5BQG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

861109:SIDU RS04230
gene id: 861109:SIDU_RS04230
uniprot id: A0A1L5BLL9
names: Similarity
messages: Belongs to the bacterial secretin family.

861109:SIDU RS15180
gene id: 861109:SIDU_RS15180
uniprot id: A0A1L5BSC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS15240
gene id: 861109:SIDU_RS15240
uniprot id: A0A1L5BS47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

861109:SIDU RS04980
gene id: 861109:SIDU_RS04980
uniprot id: A0A1L5BLU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS17780
gene id: 861109:SIDU_RS17780
uniprot id: A0A1L5BUD8
names: Similarity
messages: Belongs to the ParB family.

861109:SIDU RS04410
gene id: 861109:SIDU_RS04410
uniprot id: A0A1L5BLU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS03320
gene id: 861109:SIDU_RS03320
uniprot id: A0A1L5BTL0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS04080
gene id: 861109:SIDU_RS04080
uniprot id: A0A1L5BLS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

861109:SIDU RS16905
gene id: 861109:SIDU_RS16905
uniprot id: A0A1L5BT05
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

861109:SIDU RS07540
gene id: 861109:SIDU_RS07540
uniprot id: A0A1L5BN71
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

861109:SIDU RS05375
gene id: 861109:SIDU_RS05375
uniprot id: I5BDU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

861109:SIDU RS15360
gene id: 861109:SIDU_RS15360
uniprot id: A0A1L5BSF8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

861109:SIDU RS18325
gene id: 861109:SIDU_RS18325
uniprot id: A0A1L5BUL4
names: Similarity
messages: Belongs to the ros/MucR family.

861109:SIDU RS15340
gene id: 861109:SIDU_RS15340
uniprot id: A0A1L5BS63
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS17690
gene id: 861109:SIDU_RS17690
uniprot id: A0A1L5BU81
names: Similarity
messages: Belongs to the SBNO family.

861109:SIDU RS16265
gene id: 861109:SIDU_RS16265
uniprot id: A0A1L5BSN2
names: Similarity
messages: Belongs to the polysaccharide synthase family.

861109:SIDU RS01245
gene id: 861109:SIDU_RS01245
uniprot id: A0A1L5BKD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

861109:SIDU RS16900
gene id: 861109:SIDU_RS16900
uniprot id: A0A1L5BSY4
names: Similarity
messages: Belongs to the bacterial glucokinase family.

861109:SIDU RS01925
gene id: 861109:SIDU_RS01925
uniprot id: A0A1L5BKH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS17395
gene id: 861109:SIDU_RS17395
uniprot id: A0A1L5BU84
names: Similarity
messages: Belongs to the PhzF family.

861109:SIDU RS00550
gene id: 861109:SIDU_RS00550
uniprot id: A0A1L5BK24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

861109:SIDU RS15005
gene id: 861109:SIDU_RS15005
uniprot id: A0A1L5BS06
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

861109:SIDU RS01695
gene id: 861109:SIDU_RS01695
uniprot id: A0A1L5BKB0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

861109:SIDU RS03845
gene id: 861109:SIDU_RS03845
uniprot id: A0A1L5BLN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

861109:SIDU RS05260
gene id: 861109:SIDU_RS05260
uniprot id: A0A1L5BM32
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861109:SIDU RS05110
gene id: 861109:SIDU_RS05110
uniprot id: A0A1L5BLW3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

861109:SIDU RS07785
gene id: 861109:SIDU_RS07785
uniprot id: A0A1L5BNN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

861109:SIDU RS13415
gene id: 861109:SIDU_RS13415
uniprot id: A0A1L5BR90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

861109:SIDU RS15450
gene id: 861109:SIDU_RS15450
uniprot id: A0A1L5BS87
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

861109:SIDU RS18820
gene id: 861109:SIDU_RS18820
uniprot id: A0A1L5BUV6
names: Similarity
messages: Belongs to the RelE toxin family.

861109:SIDU RS02860
gene id: 861109:SIDU_RS02860
uniprot id: A0A1L5BKY7
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS16500
gene id: 861109:SIDU_RS16500
uniprot id: A0A1L5BSR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

861109:SIDU RS17310
gene id: 861109:SIDU_RS17310
uniprot id: A0A1L5BT93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

861109:SIDU RS06950
gene id: 861109:SIDU_RS06950
uniprot id: A0A1L5BMW3
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS07620
gene id: 861109:SIDU_RS07620
uniprot id: A0A1L5BNA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS13835
gene id: 861109:SIDU_RS13835
uniprot id: A0A1L5BRL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

861109:SIDU RS11005
gene id: 861109:SIDU_RS11005
uniprot id: A0A1L5BQ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

861109:SIDU RS17385
gene id: 861109:SIDU_RS17385
uniprot id: A0A1L5BT94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

861109:SIDU RS14655
gene id: 861109:SIDU_RS14655
uniprot id: A0A1L5BRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

861109:SIDU RS12505
gene id: 861109:SIDU_RS12505
uniprot id: A0A1L5BQN7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

861109:SIDU RS02770
gene id: 861109:SIDU_RS02770
uniprot id: A0A1L5BKX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

861109:SIDU RS01840
gene id: 861109:SIDU_RS01840
uniprot id: A0A1L5BKG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

861109:SIDU RS16565
gene id: 861109:SIDU_RS16565
uniprot id: A0A1L5BSS5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

861109:SIDU RS00320
gene id: 861109:SIDU_RS00320
uniprot id: A0A1L5BJZ5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

861109:SIDU RS04535
gene id: 861109:SIDU_RS04535
uniprot id: A0A1L5BM03
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

861109:SIDU RS15395
gene id: 861109:SIDU_RS15395
uniprot id: A0A1L5BS72
names: Similarity
messages: Belongs to the sulfatase family.

861109:SIDU RS04355
gene id: 861109:SIDU_RS04355
uniprot id: A0A1L5BLJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

861109:SIDU RS02580
gene id: 861109:SIDU_RS02580
uniprot id: A0A1L5BL03
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

861109:SIDU RS08690
gene id: 861109:SIDU_RS08690
uniprot id: A0A1L5BNS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS01400
gene id: 861109:SIDU_RS01400
uniprot id: A0A1L5BK60
names: Similarity
messages: Belongs to the band 7/mec-2 family.

861109:SIDU RS12630
gene id: 861109:SIDU_RS12630
uniprot id: A0A1L5BQV4
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

861109:SIDU RS14330
gene id: 861109:SIDU_RS14330
uniprot id: A0A1L5BRM3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

861109:SIDU RS15635
gene id: 861109:SIDU_RS15635
uniprot id: A0A1L5BSG4
names: Similarity
messages: Belongs to the peptidase U62 family.

861109:SIDU RS07640
gene id: 861109:SIDU_RS07640
uniprot id: A0A1L5BNC6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

861109:SIDU RS10220
gene id: 861109:SIDU_RS10220
uniprot id: A0A1L5BPN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

861109:SIDU RS16025
gene id: 861109:SIDU_RS16025
uniprot id: A0A1L5BSI8
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

861109:SIDU RS07880
gene id: 861109:SIDU_RS07880
uniprot id: I5BEZ7
names: Similarity
messages: Belongs to the transketolase family.

861109:SIDU RS10845
gene id: 861109:SIDU_RS10845
uniprot id: A0A1L5BTZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

861109:SIDU RS05795
gene id: 861109:SIDU_RS05795
uniprot id: A0A1L5BMF9
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

861109:SIDU RS16255
gene id: 861109:SIDU_RS16255
uniprot id: A0A1L5BSW9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

861109:SIDU RS11150
gene id: 861109:SIDU_RS11150
uniprot id: A0A1L5BQD6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

861109:SIDU RS07580
gene id: 861109:SIDU_RS07580
uniprot id: A0A1L5BNK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

861109:SIDU RS10800
gene id: 861109:SIDU_RS10800
uniprot id: A0A1L5BQ89
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

861109:SIDU RS11385
gene id: 861109:SIDU_RS11385
uniprot id: A0A1L5BQ77
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

861109:SIDU RS03160
gene id: 861109:SIDU_RS03160
uniprot id: A0A1L5BKZ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS06730
gene id: 861109:SIDU_RS06730
uniprot id: A0A1L5BMW4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

861109:SIDU RS15375
gene id: 861109:SIDU_RS15375
uniprot id: A0A1L5BS77
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

861109:SIDU RS04990
gene id: 861109:SIDU_RS04990
uniprot id: A0A1L5BM94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

861109:SIDU RS06385
gene id: 861109:SIDU_RS06385
uniprot id: A0A1L5BMY8
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

861109:SIDU RS07280
gene id: 861109:SIDU_RS07280
uniprot id: A0A1L5BNC1
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

861109:SIDU RS08355
gene id: 861109:SIDU_RS08355
uniprot id: A0A1L5BNY3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS11960
gene id: 861109:SIDU_RS11960
uniprot id: A0A1L5BQH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

861109:SIDU RS13855
gene id: 861109:SIDU_RS13855
uniprot id: A0A1L5BRN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

861109:SIDU RS10085
gene id: 861109:SIDU_RS10085
uniprot id: A0A1L5BPW5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

861109:SIDU RS03870
gene id: 861109:SIDU_RS03870
uniprot id: A0A1L5BLB2
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS02620
gene id: 861109:SIDU_RS02620
uniprot id: A0A1L5BKQ2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

861109:SIDU RS06635
gene id: 861109:SIDU_RS06635
uniprot id: A0A1L5BMU4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

861109:SIDU RS00780
gene id: 861109:SIDU_RS00780
uniprot id: A0A1L5BK57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

861109:SIDU RS11050
gene id: 861109:SIDU_RS11050
uniprot id: A0A1L5BQC9
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

861109:SIDU RS12975
gene id: 861109:SIDU_RS12975
uniprot id: A0A1L5BR63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

861109:SIDU RS17495
gene id: 861109:SIDU_RS17495
uniprot id: A0A1L5BTA4
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

861109:SIDU RS06000
gene id: 861109:SIDU_RS06000
uniprot id: A0A1L5BTR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS18895
gene id: 861109:SIDU_RS18895
uniprot id: A0A1L5BUX8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the GST superfamily.
messages: Catalyzes the degradation of 2,5-dichlorohydroquinone (2,5-DCHQ) into hydroquinone (HQ) via chlorohydroquinone (CHQ).
messages: The mechanism of this reaction probably involves a glutathione transfer: the halogen is firstly removed through substitution with glutathione, which is then removed by displacement of the aromatic moiety by a second glutathione molecule, producing oxidized glutathione (GS-SG).

861109:SIDU RS07560
gene id: 861109:SIDU_RS07560
uniprot id: A0A1L5BTV1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

861109:SIDU RS00685
gene id: 861109:SIDU_RS00685
uniprot id: A0A1L5BJU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

861109:SIDU RS00725
gene id: 861109:SIDU_RS00725
uniprot id: A0A1L5BK55
names: Cofactor
messages: Can also use Mn(2+) ion.

861109:SIDU RS15055
gene id: 861109:SIDU_RS15055
uniprot id: A0A1L5BS13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

861109:SIDU RS09120
gene id: 861109:SIDU_RS09120
uniprot id: A0A1L5BTW0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS03365
gene id: 861109:SIDU_RS03365
uniprot id: A0A1L5BL65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS10835
gene id: 861109:SIDU_RS10835
uniprot id: A0A1L5BQ63
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

861109:SIDU RS05885
gene id: 861109:SIDU_RS05885
uniprot id: A0A1L5BM84
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

861109:SIDU RS02975
gene id: 861109:SIDU_RS02975
uniprot id: A0A1L5BL46
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

861109:SIDU RS06020
gene id: 861109:SIDU_RS06020
uniprot id: A0A1L5BM93
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

861109:SIDU RS01215
gene id: 861109:SIDU_RS01215
uniprot id: A0A1L5BK28
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

861109:SIDU RS07385
gene id: 861109:SIDU_RS07385
uniprot id: A0A1L5BN85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS02160
gene id: 861109:SIDU_RS02160
uniprot id: A0A1L5BKR6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS05755
gene id: 861109:SIDU_RS05755
uniprot id: A0A1L5BMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

861109:SIDU RS15565
gene id: 861109:SIDU_RS15565
uniprot id: A0A1L5BSA5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

861109:SIDU RS08035
gene id: 861109:SIDU_RS08035
uniprot id: A0A1L5BNQ0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS07200
gene id: 861109:SIDU_RS07200
uniprot id: A0A1L5BN47
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

861109:SIDU RS16105
gene id: 861109:SIDU_RS16105
uniprot id: A0A1L5BSJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

861109:SIDU RS10120
gene id: 861109:SIDU_RS10120
uniprot id: A0A1L5BPV6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

861109:SIDU RS16080
gene id: 861109:SIDU_RS16080
uniprot id: A0A1L5BU99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS05975
gene id: 861109:SIDU_RS05975
uniprot id: A0A1L5BMS4
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS07850
gene id: 861109:SIDU_RS07850
uniprot id: A0A1L5BN90
names: Similarity
messages: Belongs to the YkuD family.

861109:SIDU RS12780
gene id: 861109:SIDU_RS12780
uniprot id: A0A1L5BQX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

861109:SIDU RS15585
gene id: 861109:SIDU_RS15585
uniprot id: A0A1L5BSB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

861109:SIDU RS05245
gene id: 861109:SIDU_RS05245
uniprot id: A0A1L5BM74
names: Similarity
messages: Belongs to the peptidase M16 family.

861109:SIDU RS17720
gene id: 861109:SIDU_RS17720
uniprot id: A0A1L5BUA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS15955
gene id: 861109:SIDU_RS15955
uniprot id: A0A1L5BSK7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

861109:SIDU RS13520
gene id: 861109:SIDU_RS13520
uniprot id: A0A1L5BRB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS12275
gene id: 861109:SIDU_RS12275
uniprot id: A0A1L5BQW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

861109:SIDU RS03155
gene id: 861109:SIDU_RS03155
uniprot id: A0A1L5BL43
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS17265
gene id: 861109:SIDU_RS17265
uniprot id: A0A1L5BTB3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

861109:SIDU RS12075
gene id: 861109:SIDU_RS12075
uniprot id: A0A1L5BQK0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

861109:SIDU RS03455
gene id: 861109:SIDU_RS03455
uniprot id: A0A1L5BLD7
names: Similarity
messages: Belongs to the ParB family.

861109:SIDU RS10810
gene id: 861109:SIDU_RS10810
uniprot id: A0A1L5BPV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

861109:SIDU RS10600
gene id: 861109:SIDU_RS10600
uniprot id: A0A1L5BPV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

861109:SIDU RS08110
gene id: 861109:SIDU_RS08110
uniprot id: A0A1L5BND2
names: Similarity
messages: Belongs to the peptidase M17 family.

861109:SIDU RS09050
gene id: 861109:SIDU_RS09050
uniprot id: A0A1L5BPB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

861109:SIDU RS01835
gene id: 861109:SIDU_RS01835
uniprot id: A0A1L5BKC6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

861109:SIDU RS02585
gene id: 861109:SIDU_RS02585
uniprot id: A0A1L5BKT2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

861109:SIDU RS10785
gene id: 861109:SIDU_RS10785
uniprot id: A0A1L5BPX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

861109:SIDU RS03370
gene id: 861109:SIDU_RS03370
uniprot id: A0A1L5BL70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS00120
gene id: 861109:SIDU_RS00120
uniprot id: A0A1L5BJW4
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS14315
gene id: 861109:SIDU_RS14315
uniprot id: A0A1L5BRW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

861109:SIDU RS05980
gene id: 861109:SIDU_RS05980
uniprot id: A0A1L5BMK2
names: Similarity
messages: Belongs to the alanine racemase family.

861109:SIDU RS01250
gene id: 861109:SIDU_RS01250
uniprot id: A0A1L5BKD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

861109:SIDU RS05120
gene id: 861109:SIDU_RS05120
uniprot id: A0A1L5BMB2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

861109:SIDU RS07865
gene id: 861109:SIDU_RS07865
uniprot id: A0A1L5BNG7
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

861109:SIDU RS15045
gene id: 861109:SIDU_RS15045
uniprot id: I5BBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS01070
gene id: 861109:SIDU_RS01070
uniprot id: A0A1L5BK01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS02835
gene id: 861109:SIDU_RS02835
uniprot id: A0A1L5BKY0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

861109:SIDU RS15385
gene id: 861109:SIDU_RS15385
uniprot id: A0A1L5BSG2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

861109:SIDU RS10015
gene id: 861109:SIDU_RS10015
uniprot id: A0A1L5BTX8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

861109:SIDU RS00870
gene id: 861109:SIDU_RS00870
uniprot id: A0A1L5BJX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

861109:SIDU RS04095
gene id: 861109:SIDU_RS04095
uniprot id: A0A1L5BLJ2
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

861109:SIDU RS10775
gene id: 861109:SIDU_RS10775
uniprot id: A0A1L5BQ75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

861109:SIDU RS18595
gene id: 861109:SIDU_RS18595
uniprot id: A0A1L5BUQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS09370
gene id: 861109:SIDU_RS09370
uniprot id: A0A1L5BPI4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

861109:SIDU RS11930
gene id: 861109:SIDU_RS11930
uniprot id: A0A1L5BQN9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

861109:SIDU RS16100
gene id: 861109:SIDU_RS16100
uniprot id: A0A1L5BSJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

861109:SIDU RS16630
gene id: 861109:SIDU_RS16630
uniprot id: A0A1L5BSS8
names: Subunit
messages: Homotetramer.

861109:SIDU RS16325
gene id: 861109:SIDU_RS16325
uniprot id: A0A1L5BSQ2
names: Similarity
messages: Belongs to the UPF0174 family.

861109:SIDU RS05960
gene id: 861109:SIDU_RS05960
uniprot id: A0A1L5BME6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

861109:SIDU RS04305
gene id: 861109:SIDU_RS04305
uniprot id: A0A1L5BLI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS18330
gene id: 861109:SIDU_RS18330
uniprot id: A0A1L5BUL2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

861109:SIDU RS01060
gene id: 861109:SIDU_RS01060
uniprot id: A0A1L5BK07
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

861109:SIDU RS09430
gene id: 861109:SIDU_RS09430
uniprot id: A0A1L5BP98
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

861109:SIDU RS02545
gene id: 861109:SIDU_RS02545
uniprot id: A0A1L5BKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

861109:SIDU RS04030
gene id: 861109:SIDU_RS04030
uniprot id: A0A1L5BLI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

861109:SIDU RS16375
gene id: 861109:SIDU_RS16375
uniprot id: A0A1L5BSQ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

861109:SIDU RS12470
gene id: 861109:SIDU_RS12470
uniprot id: A0A1L5BQX0
names: Similarity
messages: Belongs to the RelE toxin family.

861109:SIDU RS00390
gene id: 861109:SIDU_RS00390
uniprot id: A0A1L5BJN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS00345
gene id: 861109:SIDU_RS00345
uniprot id: A0A1L5BJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

861109:SIDU RS17990
gene id: 861109:SIDU_RS17990
uniprot id: A0A1L5BUF1
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS04340
gene id: 861109:SIDU_RS04340
uniprot id: A0A1L5BLW8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

861109:SIDU RS16615
gene id: 861109:SIDU_RS16615
uniprot id: A0A1L5BSW4
names: Similarity
messages: Belongs to the HesB/IscA family.

861109:SIDU RS08165
gene id: 861109:SIDU_RS08165
uniprot id: A0A1L5BNT8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

861109:SIDU RS10750
gene id: 861109:SIDU_RS10750
uniprot id: A0A1L5BQ80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

861109:SIDU RS05185
gene id: 861109:SIDU_RS05185
uniprot id: A0A1L5BM39
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

861109:SIDU RS02955
gene id: 861109:SIDU_RS02955
uniprot id: A0A1L5BL74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

861109:SIDU RS14245
gene id: 861109:SIDU_RS14245
uniprot id: A0A1L5BRT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

861109:SIDU RS07395
gene id: 861109:SIDU_RS07395
uniprot id: A0A1L5BNE0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

861109:SIDU RS13925
gene id: 861109:SIDU_RS13925
uniprot id: I5B918
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

861109:SIDU RS10730
gene id: 861109:SIDU_RS10730
uniprot id: A0A1L5BQ42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

861109:SIDU RS06800
gene id: 861109:SIDU_RS06800
uniprot id: A0A1L5BMT0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

861109:SIDU RS15815
gene id: 861109:SIDU_RS15815
uniprot id: A0A1L5BSE5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

861109:SIDU RS15605
gene id: 861109:SIDU_RS15605
uniprot id: A0A1L5BSJ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

861109:SIDU RS03340
gene id: 861109:SIDU_RS03340
uniprot id: A0A1L5BTM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

861109:SIDU RS03975
gene id: 861109:SIDU_RS03975
uniprot id: A0A1L5BLM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

861109:SIDU RS05320
gene id: 861109:SIDU_RS05320
uniprot id: A0A1L5BMF8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

861109:SIDU RS14200
gene id: 861109:SIDU_RS14200
uniprot id: A0A1L5BRU5
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

861109:SIDU RS17300
gene id: 861109:SIDU_RS17300
uniprot id: A0A1L5BT86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

861109:SIDU RS06350
gene id: 861109:SIDU_RS06350
uniprot id: A0A1L5BMY5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

861109:SIDU RS07305
gene id: 861109:SIDU_RS07305
uniprot id: A0A1L5BNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS05905
gene id: 861109:SIDU_RS05905
uniprot id: A0A1L5BMG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

861109:SIDU RS15010
gene id: 861109:SIDU_RS15010
uniprot id: A0A1L5BS05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

861109:SIDU RS12015
gene id: 861109:SIDU_RS12015
uniprot id: A0A1L5BQE9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

861109:SIDU RS02385
gene id: 861109:SIDU_RS02385
uniprot id: A0A1L5BKX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

861109:SIDU RS00380
gene id: 861109:SIDU_RS00380
uniprot id: A0A1L5BK02
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

861109:SIDU RS10495
gene id: 861109:SIDU_RS10495
uniprot id: A0A1L5BTZ1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

861109:SIDU RS00695
gene id: 861109:SIDU_RS00695
uniprot id: A0A1L5BK17
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

861109:SIDU RS10560
gene id: 861109:SIDU_RS10560
uniprot id: A0A1L5BQ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

861109:SIDU RS09795
gene id: 861109:SIDU_RS09795
uniprot id: A0A1L5BPE9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS12590
gene id: 861109:SIDU_RS12590
uniprot id: A0A1L5BQU6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861109:SIDU RS12020
gene id: 861109:SIDU_RS12020
uniprot id: A0A1L5BQF9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

861109:SIDU RS09215
gene id: 861109:SIDU_RS09215
uniprot id: A0A1L5BP59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS01230
gene id: 861109:SIDU_RS01230
uniprot id: A0A1L5BK34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

861109:SIDU RS00330
gene id: 861109:SIDU_RS00330
uniprot id: A0A1L5BJN1
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.

861109:SIDU RS19005
gene id: 861109:SIDU_RS19005
uniprot id: A0A1L5BUY5
names: Similarity
messages: Belongs to the transposase 7 family.

861109:SIDU RS11235
gene id: 861109:SIDU_RS11235
uniprot id: A0A1L5BU01
names: Similarity
messages: Belongs to the UPF0246 family.

861109:SIDU RS14705
gene id: 861109:SIDU_RS14705
uniprot id: A0A1L5BS38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

861109:SIDU RS03820
gene id: 861109:SIDU_RS03820
uniprot id: A0A1L5BLN1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

861109:SIDU RS01390
gene id: 861109:SIDU_RS01390
uniprot id: A0A1L5BK99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS05210
gene id: 861109:SIDU_RS05210
uniprot id: A0A1L5BM22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS06875
gene id: 861109:SIDU_RS06875
uniprot id: A0A1L5BTS7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

861109:SIDU RS15680
gene id: 861109:SIDU_RS15680
uniprot id: A0A1L5BSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS14695
gene id: 861109:SIDU_RS14695
uniprot id: A0A1L5BRV8
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS07065
gene id: 861109:SIDU_RS07065
uniprot id: A0A1L5BN82
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

861109:SIDU RS16435
gene id: 861109:SIDU_RS16435
uniprot id: A0A1L5BSS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS05900
gene id: 861109:SIDU_RS05900
uniprot id: A0A1L5BMQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

861109:SIDU RS10715
gene id: 861109:SIDU_RS10715
uniprot id: A0A1L5BPT6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

861109:SIDU RS05560
gene id: 861109:SIDU_RS05560
uniprot id: A0A1L5BM47
names: Similarity
messages: Belongs to the phosphohexose mutase family.

861109:SIDU RS18275
gene id: 861109:SIDU_RS18275
uniprot id: A0A1L5BUK7
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

861109:SIDU RS16040
gene id: 861109:SIDU_RS16040
uniprot id: A0A1L5BSJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

861109:SIDU RS13495
gene id: 861109:SIDU_RS13495
uniprot id: I5BAA7
names: Subcellular Location Annotation
messages: Cytoplasm

861109:SIDU RS05290
gene id: 861109:SIDU_RS05290
uniprot id: A0A1L5BM45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

861109:SIDU RS06475
gene id: 861109:SIDU_RS06475
uniprot id: A0A1L5BML9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

861109:SIDU RS12745
gene id: 861109:SIDU_RS12745
uniprot id: A0A1L5BQW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS04695
gene id: 861109:SIDU_RS04695
uniprot id: A0A1L5BLU8
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

861109:SIDU RS10625
gene id: 861109:SIDU_RS10625
uniprot id: A0A1L5BPR7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

861109:SIDU RS17950
gene id: 861109:SIDU_RS17950
uniprot id: A0A1L5BUD4
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

861109:SIDU RS06790
gene id: 861109:SIDU_RS06790
uniprot id: A0A1L5BN62
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

861109:SIDU RS07000
gene id: 861109:SIDU_RS07000
uniprot id: A0A1L5BMS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

861109:SIDU RS05915
gene id: 861109:SIDU_RS05915
uniprot id: A0A1L5BME1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

861109:SIDU RS05550
gene id: 861109:SIDU_RS05550
uniprot id: A0A1L5BMA5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

861109:SIDU RS09730
gene id: 861109:SIDU_RS09730
uniprot id: A0A1L5BPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

861109:SIDU RS14620
gene id: 861109:SIDU_RS14620
uniprot id: A0A1L5BS20
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

861109:SIDU RS09420
gene id: 861109:SIDU_RS09420
uniprot id: A0A1L5BPJ4
names: Similarity
messages: Belongs to the YciI family.

861109:SIDU RS12795
gene id: 861109:SIDU_RS12795
uniprot id: A0A1L5BQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

861109:SIDU RS09110
gene id: 861109:SIDU_RS09110
uniprot id: A0A1L5BNZ5
names: Similarity
messages: Belongs to the peptidase M24B family.

861109:SIDU RS04810
gene id: 861109:SIDU_RS04810
uniprot id: A0A1L5BM48
names: Similarity
messages: Belongs to the TrpF family.

861109:SIDU RS15770
gene id: 861109:SIDU_RS15770
uniprot id: A0A1L5BSI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

861109:SIDU RS07645
gene id: 861109:SIDU_RS07645
uniprot id: A0A1L5BN89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

861109:SIDU RS01130
gene id: 861109:SIDU_RS01130
uniprot id: I5BFM7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

861109:SIDU RS15000
gene id: 861109:SIDU_RS15000
uniprot id: A0A1L5BS90
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

861109:SIDU RS14135
gene id: 861109:SIDU_RS14135
uniprot id: A0A1L5BRK1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

861109:SIDU RS10720
gene id: 861109:SIDU_RS10720
uniprot id: A0A1L5BPX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

861109:SIDU RS07805
gene id: 861109:SIDU_RS07805
uniprot id: A0A1L5BNA7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

861109:SIDU RS02335
gene id: 861109:SIDU_RS02335
uniprot id: A0A1L5BKW0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS01955
gene id: 861109:SIDU_RS01955
uniprot id: A0A1L5BKI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS05810
gene id: 861109:SIDU_RS05810
uniprot id: A0A1L5BMF0
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

861109:SIDU RS05725
gene id: 861109:SIDU_RS05725
uniprot id: A0A1L5BMD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

861109:SIDU RS05500
gene id: 861109:SIDU_RS05500
uniprot id: A0A1L5BM96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

861109:SIDU RS06555
gene id: 861109:SIDU_RS06555
uniprot id: A0A1L5BMS2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

861109:SIDU RS20115
gene id: 861109:SIDU_RS20115
uniprot id: A0A1L5BT75
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

861109:SIDU RS08645
gene id: 861109:SIDU_RS08645
uniprot id: A0A1L5BNR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS09015
gene id: 861109:SIDU_RS09015
uniprot id: A0A1L5BP15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS10165
gene id: 861109:SIDU_RS10165
uniprot id: A0A1L5BPM9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

861109:SIDU RS00885
gene id: 861109:SIDU_RS00885
uniprot id: A0A1L5BJX7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS06365
gene id: 861109:SIDU_RS06365
uniprot id: A0A1L5BMK0
names: Similarity
messages: Belongs to the acylphosphatase family.

861109:SIDU RS11765
gene id: 861109:SIDU_RS11765
uniprot id: A0A1L5BQK8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

861109:SIDU RS06840
gene id: 861109:SIDU_RS06840
uniprot id: A0A1L5BMU1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

861109:SIDU RS07780
gene id: 861109:SIDU_RS07780
uniprot id: A0A1L5BNF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

861109:SIDU RS10235
gene id: 861109:SIDU_RS10235
uniprot id: A0A1L5BPN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

861109:SIDU RS12595
gene id: 861109:SIDU_RS12595
uniprot id: A0A1L5BQS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

861109:SIDU RS15595
gene id: 861109:SIDU_RS15595
uniprot id: A0A1L5BSA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

861109:SIDU RS10580
gene id: 861109:SIDU_RS10580
uniprot id: A0A1L5BQ50
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

861109:SIDU RS16785
gene id: 861109:SIDU_RS16785
uniprot id: A0A1L5BSW5
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

861109:SIDU RS17915
gene id: 861109:SIDU_RS17915
uniprot id: A0A1L5BUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS12890
gene id: 861109:SIDU_RS12890
uniprot id: A0A1L5BQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

861109:SIDU RS14260
gene id: 861109:SIDU_RS14260
uniprot id: A0A1L5BRK8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

861109:SIDU RS18175
gene id: 861109:SIDU_RS18175
uniprot id: P59766
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HCH dehydrochlorinase family.
messages: Catalyzes the conversion of the important environmental pollutant gamma-hexachlorocyclohexane (gamma-HCH or lindane) to 1,3,4,6-tetrachloro-1,4-cyclohexadiene (1,4-TCDN) via gamma-pentachlorocyclohexene (gamma-PCCH) (PubMed:12450824). Proceeds by two successive 1,2-anti conformationally dependent dehydrochlorinations (By similarity). Also shows activity with alpha- and delta-HCH, giving alpha- and delta-PCCH respectively, but not with the beta isomer (PubMed:12450824).
messages: Gamma-hexachlorocyclohexane (lindane) is an organochlorine insecticide which has been used worldwide since the 1940s. Because of its toxicity and long persistence in soil, most countries have prohibited the use of gamma-HCH. However, many contaminated sites still remain throughout the world.
messages: Homotrimer.
messages: Is not N-terminally processed during export, so it may be secreted into the periplasmic space via a hitherto unknown mechanism.
messages: Periplasm

861109:SIDU RS04730
gene id: 861109:SIDU_RS04730
uniprot id: A0A1L5BLU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS12045
gene id: 861109:SIDU_RS12045
uniprot id: A0A1L5BQF3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

861109:SIDU RS15275
gene id: 861109:SIDU_RS15275
uniprot id: A0A1L5BS58
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

861109:SIDU RS09225
gene id: 861109:SIDU_RS09225
uniprot id: A0A1L5BP25
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

861109:SIDU RS13345
gene id: 861109:SIDU_RS13345
uniprot id: A0A1L5BR66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

861109:SIDU RS07320
gene id: 861109:SIDU_RS07320
uniprot id: A0A1L5BTT4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

861109:SIDU RS10910
gene id: 861109:SIDU_RS10910
uniprot id: A0A1L5BPV4
names: Similarity
messages: Belongs to the universal stress protein A family.

861109:SIDU RS18865
gene id: 861109:SIDU_RS18865
uniprot id: A0A1L5BUW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS14680
gene id: 861109:SIDU_RS14680
uniprot id: A0A1L5BS42
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

861109:SIDU RS13295
gene id: 861109:SIDU_RS13295
uniprot id: A0A1L5BR45
names: Subcellular Location Annotation
messages: Cell outer membrane

861109:SIDU RS14985
gene id: 861109:SIDU_RS14985
uniprot id: A0A1L5BU64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS09935
gene id: 861109:SIDU_RS09935
uniprot id: A0A1L5BPE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

861109:SIDU RS18555
gene id: 861109:SIDU_RS18555
uniprot id: A0A1L5BUP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS06915
gene id: 861109:SIDU_RS06915
uniprot id: A0A1L5BMW0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

861109:SIDU RS01795
gene id: 861109:SIDU_RS01795
uniprot id: A0A1L5BKK9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS03940
gene id: 861109:SIDU_RS03940
uniprot id: A0A1L5BTM6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS04020
gene id: 861109:SIDU_RS04020
uniprot id: I5BED1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

861109:SIDU RS06835
gene id: 861109:SIDU_RS06835
uniprot id: A0A1L5BMQ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

861109:SIDU RS10325
gene id: 861109:SIDU_RS10325
uniprot id: A0A1L5BPZ1
names: Similarity
messages: Belongs to the FGGY kinase family.

861109:SIDU RS04205
gene id: 861109:SIDU_RS04205
uniprot id: I5BEC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

861109:SIDU RS00975
gene id: 861109:SIDU_RS00975
uniprot id: A0A1L5BJZ0
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

861109:SIDU RS02855
gene id: 861109:SIDU_RS02855
uniprot id: A0A1L5BL54
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS04435
gene id: 861109:SIDU_RS04435
uniprot id: I5BCL0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

861109:SIDU RS01185
gene id: 861109:SIDU_RS01185
uniprot id: A0A1L5BKC2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

861109:SIDU RS08630
gene id: 861109:SIDU_RS08630
uniprot id: A0A1L5BP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS04690
gene id: 861109:SIDU_RS04690
uniprot id: A0A1L5BM24
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

861109:SIDU RS15905
gene id: 861109:SIDU_RS15905
uniprot id: A0A1L5BSG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

861109:SIDU RS01460
gene id: 861109:SIDU_RS01460
uniprot id: A0A1L5BK64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

861109:SIDU RS06360
gene id: 861109:SIDU_RS06360
uniprot id: A0A1L5BMQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

861109:SIDU RS17150
gene id: 861109:SIDU_RS17150
uniprot id: A0A1L5BT44
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS05670
gene id: 861109:SIDU_RS05670
uniprot id: A0A1L5BTQ4
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

861109:SIDU RS04750
gene id: 861109:SIDU_RS04750
uniprot id: A0A1L5BLQ4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

861109:SIDU RS08585
gene id: 861109:SIDU_RS08585
uniprot id: A0A1L5BNU3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

861109:SIDU RS09255
gene id: 861109:SIDU_RS09255
uniprot id: A0A1L5BP21
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

861109:SIDU RS13585
gene id: 861109:SIDU_RS13585
uniprot id: A0A1L5BRK9
names: Similarity
messages: Belongs to the virb1 family.

861109:SIDU RS18160
gene id: 861109:SIDU_RS18160
uniprot id: A0A1L5BUG8
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the dehydrogenation of 2,5-dichloro-2,5-cyclohexadiene-1,4-diol (2,5-DDOL) to 2,5-dichlorohydroquinone (2,5-DCHQ), a step in the degradation of gamma-hexachlorocyclohexane (gamma-HCH or lindane).

861109:SIDU RS18680
gene id: 861109:SIDU_RS18680
uniprot id: A0A1L5BUS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS02445
gene id: 861109:SIDU_RS02445
uniprot id: A0A1L5BKR3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS04585
gene id: 861109:SIDU_RS04585
uniprot id: A0A1L5BTT0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

861109:SIDU RS07615
gene id: 861109:SIDU_RS07615
uniprot id: A0A1L5BTT8
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

861109:SIDU RS05520
gene id: 861109:SIDU_RS05520
uniprot id: A0A1L5BMA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

861109:SIDU RS14195
gene id: 861109:SIDU_RS14195
uniprot id: A0A1L5BRJ8
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

861109:SIDU RS17960
gene id: 861109:SIDU_RS17960
uniprot id: A0A1L5BUG0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

861109:SIDU RS00965
gene id: 861109:SIDU_RS00965
uniprot id: A0A1L5BK98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

861109:SIDU RS16035
gene id: 861109:SIDU_RS16035
uniprot id: A0A1L5BSJ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS13410
gene id: 861109:SIDU_RS13410
uniprot id: A0A1L5BR67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

861109:SIDU RS09775
gene id: 861109:SIDU_RS09775
uniprot id: A0A1L5BPB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

861109:SIDU RS05285
gene id: 861109:SIDU_RS05285
uniprot id: A0A1L5BME4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

861109:SIDU RS08580
gene id: 861109:SIDU_RS08580
uniprot id: A0A1L5BP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS08810
gene id: 861109:SIDU_RS08810
uniprot id: I5BBP1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

861109:SIDU RS02440
gene id: 861109:SIDU_RS02440
uniprot id: A0A1L5BKY4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

861109:SIDU RS16150
gene id: 861109:SIDU_RS16150
uniprot id: A0A1L5BSV1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

861109:SIDU RS16835
gene id: 861109:SIDU_RS16835
uniprot id: A0A1L5BSX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

861109:SIDU RS09840
gene id: 861109:SIDU_RS09840
uniprot id: A0A1L5BPG1
names: Similarity
messages: Belongs to the Tim44 family.

861109:SIDU RS16400
gene id: 861109:SIDU_RS16400
uniprot id: A0A1L5BSP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

861109:SIDU RS05585
gene id: 861109:SIDU_RS05585
uniprot id: A0A1L5BMB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

861109:SIDU RS07245
gene id: 861109:SIDU_RS07245
uniprot id: A0A1L5BN10
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

861109:SIDU RS18440
gene id: 861109:SIDU_RS18440
uniprot id: A0A1L5BUN0
names: Similarity
messages: Belongs to the GSP E family.

861109:SIDU RS12950
gene id: 861109:SIDU_RS12950
uniprot id: A0A1L5BQY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

861109:SIDU RS13030
gene id: 861109:SIDU_RS13030
uniprot id: A0A1L5BRB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS01785
gene id: 861109:SIDU_RS01785
uniprot id: A0A1L5BKF8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS11175
gene id: 861109:SIDU_RS11175
uniprot id: A0A1L5BQE8
names: Similarity
messages: Belongs to the MipA/OmpV family.

861109:SIDU RS05305
gene id: 861109:SIDU_RS05305
uniprot id: A0A1L5BM78
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

861109:SIDU RS00915
gene id: 861109:SIDU_RS00915
uniprot id: A0A1L5BJX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

861109:SIDU RS04190
gene id: 861109:SIDU_RS04190
uniprot id: A0A1L5BLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

861109:SIDU RS05395
gene id: 861109:SIDU_RS05395
uniprot id: A0A1L5BMG2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

861109:SIDU RS12940
gene id: 861109:SIDU_RS12940
uniprot id: A0A1L5BR78
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

861109:SIDU RS09870
gene id: 861109:SIDU_RS09870
uniprot id: A0A1L5BPS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

861109:SIDU RS05890
gene id: 861109:SIDU_RS05890
uniprot id: A0A1L5BTS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

861109:SIDU RS13100
gene id: 861109:SIDU_RS13100
uniprot id: A0A1L5BR11
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

861109:SIDU RS06985
gene id: 861109:SIDU_RS06985
uniprot id: A0A1L5BN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

861109:SIDU RS01355
gene id: 861109:SIDU_RS01355
uniprot id: A0A1L5BKG9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861109:SIDU RS08830
gene id: 861109:SIDU_RS08830
uniprot id: I5BBN7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

861109:SIDU RS02925
gene id: 861109:SIDU_RS02925
uniprot id: A0A1L5BL64
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

861109:SIDU RS15405
gene id: 861109:SIDU_RS15405
uniprot id: A0A1L5BS79
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

861109:SIDU RS00750
gene id: 861109:SIDU_RS00750
uniprot id: A0A1L5BK26
names: Similarity
messages: Belongs to the BolA/IbaG family.

861109:SIDU RS13290
gene id: 861109:SIDU_RS13290
uniprot id: A0A1L5BR56
names: Similarity
messages: Belongs to the RecJ family.

861109:SIDU RS01470
gene id: 861109:SIDU_RS01470
uniprot id: A0A1L5BKI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

861109:SIDU RS08885
gene id: 861109:SIDU_RS08885
uniprot id: A0A1L5BNS1
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

861109:SIDU RS14825
gene id: 861109:SIDU_RS14825
uniprot id: A0A1L5BRX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

861109:SIDU RS16225
gene id: 861109:SIDU_RS16225
uniprot id: A0A1L5BSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

861109:SIDU RS13605
gene id: 861109:SIDU_RS13605
uniprot id: A0A1L5BRA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS07420
gene id: 861109:SIDU_RS07420
uniprot id: A0A1L5BN86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

861109:SIDU RS10535
gene id: 861109:SIDU_RS10535
uniprot id: A0A1L5BPT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

861109:SIDU RS09710
gene id: 861109:SIDU_RS09710
uniprot id: A0A1L5BPA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

861109:SIDU RS13640
gene id: 861109:SIDU_RS13640
uniprot id: A0A1L5BRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

861109:SIDU RS11265
gene id: 861109:SIDU_RS11265
uniprot id: A0A1L5BQ57
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

861109:SIDU RS03880
gene id: 861109:SIDU_RS03880
uniprot id: A0A1L5BLP0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

861109:SIDU RS06340
gene id: 861109:SIDU_RS06340
uniprot id: A0A1L5BMF5
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

861109:SIDU RS03390
gene id: 861109:SIDU_RS03390
uniprot id: A0A1L5BLD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

861109:SIDU RS01600
gene id: 861109:SIDU_RS01600
uniprot id: A0A1L5BK92
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

861109:SIDU RS13915
gene id: 861109:SIDU_RS13915
uniprot id: A0A1L5BRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

861109:SIDU RS15625
gene id: 861109:SIDU_RS15625
uniprot id: A0A1L5BSD5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

861109:SIDU RS18635
gene id: 861109:SIDU_RS18635
uniprot id: A0A1L5BUR2
names: Similarity
messages: Belongs to the CFA/CMAS family.

861109:SIDU RS09470
gene id: 861109:SIDU_RS09470
uniprot id: A0A1L5BP57
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS08425
gene id: 861109:SIDU_RS08425
uniprot id: A0A1L5BNQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS09200
gene id: 861109:SIDU_RS09200
uniprot id: A0A1L5BNZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

861109:SIDU RS10025
gene id: 861109:SIDU_RS10025
uniprot id: A0A1L5BPF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

861109:SIDU RS02550
gene id: 861109:SIDU_RS02550
uniprot id: A0A1L5BKS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

861109:SIDU RS15760
gene id: 861109:SIDU_RS15760
uniprot id: A0A1L5BSM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS09245
gene id: 861109:SIDU_RS09245
uniprot id: A0A1L5BP53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

861109:SIDU RS10905
gene id: 861109:SIDU_RS10905
uniprot id: A0A1L5BPZ6
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS16335
gene id: 861109:SIDU_RS16335
uniprot id: A0A1L5BSX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

861109:SIDU RS12475
gene id: 861109:SIDU_RS12475
uniprot id: A0A1L5BQS4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

861109:SIDU RS00455
gene id: 861109:SIDU_RS00455
uniprot id: A0A1L5BJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS11700
gene id: 861109:SIDU_RS11700
uniprot id: A0A1L5BQM3
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

861109:SIDU RS04915
gene id: 861109:SIDU_RS04915
uniprot id: A0A1L5BLT3
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

861109:SIDU RS09105
gene id: 861109:SIDU_RS09105
uniprot id: A0A1L5BP33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

861109:SIDU RS08685
gene id: 861109:SIDU_RS08685
uniprot id: A0A1L5BNW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

861109:SIDU RS13740
gene id: 861109:SIDU_RS13740
uniprot id: A0A1L5BRC4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

861109:SIDU RS06375
gene id: 861109:SIDU_RS06375
uniprot id: A0A1L5BTS1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

861109:SIDU RS01380
gene id: 861109:SIDU_RS01380
uniprot id: A0A1L5BKF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS07545
gene id: 861109:SIDU_RS07545
uniprot id: A0A1L5BNB5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS06960
gene id: 861109:SIDU_RS06960
uniprot id: A0A1L5BN93
names: Subcellular Location Annotation
messages: Mitochondrion

861109:SIDU RS13775
gene id: 861109:SIDU_RS13775
uniprot id: A0A1L5BRC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

861109:SIDU RS05985
gene id: 861109:SIDU_RS05985
uniprot id: A0A1L5BTQ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

861109:SIDU RS17870
gene id: 861109:SIDU_RS17870
uniprot id: A0A1L5BUB7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

861109:SIDU RS17460
gene id: 861109:SIDU_RS17460
uniprot id: A0A1L5BTC6
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

861109:SIDU RS05005
gene id: 861109:SIDU_RS05005
uniprot id: A0A1L5BLW2
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS09275
gene id: 861109:SIDU_RS09275
uniprot id: A0A1L5BP34
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS02400
gene id: 861109:SIDU_RS02400
uniprot id: A0A1L5BKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

861109:SIDU RS16200
gene id: 861109:SIDU_RS16200
uniprot id: A0A1L5BSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

861109:SIDU RS04850
gene id: 861109:SIDU_RS04850
uniprot id: A0A1L5BM21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

861109:SIDU RS01935
gene id: 861109:SIDU_RS01935
uniprot id: A0A1L5BKE0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS11950
gene id: 861109:SIDU_RS11950
uniprot id: A0A1L5BU09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861109:SIDU RS10710
gene id: 861109:SIDU_RS10710
uniprot id: A0A1L5BPT1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

861109:SIDU RS06695
gene id: 861109:SIDU_RS06695
uniprot id: A0A1L5BMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

861109:SIDU RS10570
gene id: 861109:SIDU_RS10570
uniprot id: A0A1L5BPN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS18775
gene id: 861109:SIDU_RS18775
uniprot id: A0A1L5BUT8
names: Similarity
messages: Belongs to the ParB family.

861109:SIDU RS08375
gene id: 861109:SIDU_RS08375
uniprot id: A0A1L5BNP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS14990
gene id: 861109:SIDU_RS14990
uniprot id: A0A1L5BS02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

861109:SIDU RS17045
gene id: 861109:SIDU_RS17045
uniprot id: A0A1L5BT34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

861109:SIDU RS07355
gene id: 861109:SIDU_RS07355
uniprot id: A0A1L5BMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

861109:SIDU RS09035
gene id: 861109:SIDU_RS09035
uniprot id: A0A1L5BP02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

861109:SIDU RS11880
gene id: 861109:SIDU_RS11880
uniprot id: A0A1L5BQM8
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).

861109:SIDU RS10155
gene id: 861109:SIDU_RS10155
uniprot id: A0A1L5BPH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

861109:SIDU RS15985
gene id: 861109:SIDU_RS15985
uniprot id: A0A1L5BSI6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

861109:SIDU RS00525
gene id: 861109:SIDU_RS00525
uniprot id: A0A1L5BJY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS01100
gene id: 861109:SIDU_RS01100
uniprot id: A0A1L5BK11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

861109:SIDU RS10335
gene id: 861109:SIDU_RS10335
uniprot id: A0A1L5BPQ1
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

861109:SIDU RS02600
gene id: 861109:SIDU_RS02600
uniprot id: A0A1L5BKP0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

861109:SIDU RS04375
gene id: 861109:SIDU_RS04375
uniprot id: A0A1L5BLN6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

861109:SIDU RS15690
gene id: 861109:SIDU_RS15690
uniprot id: A0A1L5BSD7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

861109:SIDU RS08805
gene id: 861109:SIDU_RS08805
uniprot id: I5BF46
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

861109:SIDU RS06690
gene id: 861109:SIDU_RS06690
uniprot id: A0A1L5BMS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

861109:SIDU RS04495
gene id: 861109:SIDU_RS04495
uniprot id: A0A1L5BLL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

861109:SIDU RS05380
gene id: 861109:SIDU_RS05380
uniprot id: I5BDU3
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

861109:SIDU RS01360
gene id: 861109:SIDU_RS01360
uniprot id: A0A1L5BK52
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS03240
gene id: 861109:SIDU_RS03240
uniprot id: A0A1L5BL20
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

861109:SIDU RS08545
gene id: 861109:SIDU_RS08545
uniprot id: A0A1L5BNT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

861109:SIDU RS05595
gene id: 861109:SIDU_RS05595
uniprot id: A0A1L5BMC7
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

861109:SIDU RS14370
gene id: 861109:SIDU_RS14370
uniprot id: A0A1L5BRX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

861109:SIDU RS00250
gene id: 861109:SIDU_RS00250
uniprot id: A0A1L5BJM3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

861109:SIDU RS17390
gene id: 861109:SIDU_RS17390
uniprot id: A0A1L5BT78
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS04125
gene id: 861109:SIDU_RS04125
uniprot id: A0A1L5BLJ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS06415
gene id: 861109:SIDU_RS06415
uniprot id: A0A1L5BMQ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

861109:SIDU RS11505
gene id: 861109:SIDU_RS11505
uniprot id: A0A1L5BQ97
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

861109:SIDU RS07775
gene id: 861109:SIDU_RS07775
uniprot id: A0A1L5BNB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

861109:SIDU RS05730
gene id: 861109:SIDU_RS05730
uniprot id: A0A1L5BM72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

861109:SIDU RS15795
gene id: 861109:SIDU_RS15795
uniprot id: A0A1L5BU83
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

861109:SIDU RS09785
gene id: 861109:SIDU_RS09785
uniprot id: A0A1L5BPQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

861109:SIDU RS00440
gene id: 861109:SIDU_RS00440
uniprot id: A0A1L5BK12
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

861109:SIDU RS11015
gene id: 861109:SIDU_RS11015
uniprot id: A0A1L5BQ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

861109:SIDU RS16020
gene id: 861109:SIDU_RS16020
uniprot id: A0A1L5BSH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

861109:SIDU RS15685
gene id: 861109:SIDU_RS15685
uniprot id: A0A1L5BSH6
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS06005
gene id: 861109:SIDU_RS06005
uniprot id: A0A1L5BTQ8
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

861109:SIDU RS03045
gene id: 861109:SIDU_RS03045
uniprot id: I5BBR1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

861109:SIDU RS17380
gene id: 861109:SIDU_RS17380
uniprot id: A0A1L5BT81
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

861109:SIDU RS12920
gene id: 861109:SIDU_RS12920
uniprot id: A0A1L5BU22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

861109:SIDU RS06975
gene id: 861109:SIDU_RS06975
uniprot id: A0A1L5BMW7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

861109:SIDU RS02110
gene id: 861109:SIDU_RS02110
uniprot id: A0A1L5BKS3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

861109:SIDU RS18090
gene id: 861109:SIDU_RS18090
uniprot id: A0A1L5BUH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

861109:SIDU RS16640
gene id: 861109:SIDU_RS16640
uniprot id: A0A1L5BSW3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

861109:SIDU RS07140
gene id: 861109:SIDU_RS07140
uniprot id: A0A1L5BN38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

861109:SIDU RS05710
gene id: 861109:SIDU_RS05710
uniprot id: A0A1L5BMD0
names: Similarity
messages: Belongs to the CFA/CMAS family.

861109:SIDU RS17335
gene id: 861109:SIDU_RS17335
uniprot id: A0A1L5BT88
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

861109:SIDU RS05030
gene id: 861109:SIDU_RS05030
uniprot id: A0A1L5BLZ5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

861109:SIDU RS14265
gene id: 861109:SIDU_RS14265
uniprot id: A0A1L5BRV5
names: Similarity
messages: Belongs to the peptidase S9A family.

861109:SIDU RS09490
gene id: 861109:SIDU_RS09490
uniprot id: A0A1L5BP63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

861109:SIDU RS13750
gene id: 861109:SIDU_RS13750
uniprot id: A0A1L5BRF1
names: Similarity
messages: Belongs to the ArsC family.

861109:SIDU RS09390
gene id: 861109:SIDU_RS09390
uniprot id: A0A1L5BP94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

861109:SIDU RS06470
gene id: 861109:SIDU_RS06470
uniprot id: A0A1L5BMR8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

861109:SIDU RS11620
gene id: 861109:SIDU_RS11620
uniprot id: A0A1L5BQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS17975
gene id: 861109:SIDU_RS17975
uniprot id: A0A1L5BUE0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

861109:SIDU RS04085
gene id: 861109:SIDU_RS04085
uniprot id: A0A1L5BTM9
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

861109:SIDU RS13715
gene id: 861109:SIDU_RS13715
uniprot id: A0A1L5BRB8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

861109:SIDU RS00740
gene id: 861109:SIDU_RS00740
uniprot id: A0A1L5BJV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

861109:SIDU RS06400
gene id: 861109:SIDU_RS06400
uniprot id: A0A1L5BMH1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

861109:SIDU RS11275
gene id: 861109:SIDU_RS11275
uniprot id: A0A1L5BQ19
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

861109:SIDU RS00630
gene id: 861109:SIDU_RS00630
uniprot id: I5BB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS05950
gene id: 861109:SIDU_RS05950
uniprot id: A0A1L5BMR7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

861109:SIDU RS04120
gene id: 861109:SIDU_RS04120
uniprot id: A0A1L5BLK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

861109:SIDU RS09180
gene id: 861109:SIDU_RS09180
uniprot id: A0A1L5BP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

861109:SIDU RS07045
gene id: 861109:SIDU_RS07045
uniprot id: A0A1L5BMW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

861109:SIDU RS08120
gene id: 861109:SIDU_RS08120
uniprot id: A0A1L5BNF5
names: Similarity
messages: Belongs to the peptidase C40 family.

861109:SIDU RS09360
gene id: 861109:SIDU_RS09360
uniprot id: A0A1L5BP22
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS12925
gene id: 861109:SIDU_RS12925
uniprot id: A0A1L5BR07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. In Gram-negative bacteria, at least four rings, L, P, S and M are present, whereas Gram-positive bacteria lack the L and P rings. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF build up the proximal portion of the rod with about 6 subunits each. Rod assembly occurs by export via the flagellum-specific pathway of its constituent proteins and by their incorporation into the rod structure in the probable order of FlgB, FlgC, FlgF and FlgG. Another protein, FliE, also assembles onto the stable rod structure.

861109:SIDU RS11540
gene id: 861109:SIDU_RS11540
uniprot id: A0A1L5BU05
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the degradation of 2,5-dichloro-2,5-cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ) in vitro. LinX appears not to be involved in gamma-hexachlorocyclohexane (gamma-HCH) degradation pathway, in contrast to LinC which has the same enzymatic activity.

861109:SIDU RS10700
gene id: 861109:SIDU_RS10700
uniprot id: A0A1L5BQ70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

861109:SIDU RS08185
gene id: 861109:SIDU_RS08185
uniprot id: A0A1L5BNG6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

861109:SIDU RS05565
gene id: 861109:SIDU_RS05565
uniprot id: A0A1L5BMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

861109:SIDU RS05000
gene id: 861109:SIDU_RS05000
uniprot id: A0A1L5BM09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS11360
gene id: 861109:SIDU_RS11360
uniprot id: A0A1L5BQ45
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

861109:SIDU RS12280
gene id: 861109:SIDU_RS12280
uniprot id: A0A1L5BQN2
names: Similarity
messages: Belongs to the GSP E family.

861109:SIDU RS08380
gene id: 861109:SIDU_RS08380
uniprot id: A0A1L5BNX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS09790
gene id: 861109:SIDU_RS09790
uniprot id: A0A1L5BPM2
names: Similarity
messages: Belongs to the TrpC family.

861109:SIDU RS18725
gene id: 861109:SIDU_RS18725
uniprot id: A0A1L5BUS2
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS06640
gene id: 861109:SIDU_RS06640
uniprot id: A0A1L5BMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

861109:SIDU RS04575
gene id: 861109:SIDU_RS04575
uniprot id: A0A1L5BLT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

861109:SIDU RS09310
gene id: 861109:SIDU_RS09310
uniprot id: A0A1L5BP31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

861109:SIDU RS09485
gene id: 861109:SIDU_RS09485
uniprot id: A0A1L5BPA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

861109:SIDU RS16030
gene id: 861109:SIDU_RS16030
uniprot id: A0A1L5BSS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

861109:SIDU RS02295
gene id: 861109:SIDU_RS02295
uniprot id: A0A1L5BTK5
names: Similarity
messages: Belongs to the YciI family.

861109:SIDU RS00675
gene id: 861109:SIDU_RS00675
uniprot id: I5BAR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

861109:SIDU RS01160
gene id: 861109:SIDU_RS01160
uniprot id: A0A1L5BK20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

861109:SIDU RS15910
gene id: 861109:SIDU_RS15910
uniprot id: A0A1L5BSH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

861109:SIDU RS02240
gene id: 861109:SIDU_RS02240
uniprot id: A0A1L5BKI1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

861109:SIDU RS16535
gene id: 861109:SIDU_RS16535
uniprot id: A0A1L5BSU3
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS12825
gene id: 861109:SIDU_RS12825
uniprot id: A0A1L5BQV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

861109:SIDU RS06380
gene id: 861109:SIDU_RS06380
uniprot id: A0A1L5BMR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

861109:SIDU RS07505
gene id: 861109:SIDU_RS07505
uniprot id: A0A1L5BN83
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

861109:SIDU RS18570
gene id: 861109:SIDU_RS18570
uniprot id: A0A1L5BUP9
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

861109:SIDU RS01930
gene id: 861109:SIDU_RS01930
uniprot id: A0A1L5BKI5
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS17830
gene id: 861109:SIDU_RS17830
uniprot id: A0A1L5BUK1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS15140
gene id: 861109:SIDU_RS15140
uniprot id: I5BEJ3
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

861109:SIDU RS00935
gene id: 861109:SIDU_RS00935
uniprot id: A0A1L5BJY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

861109:SIDU RS04855
gene id: 861109:SIDU_RS04855
uniprot id: A0A1L5BLW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

861109:SIDU RS14375
gene id: 861109:SIDU_RS14375
uniprot id: A0A1L5BRP2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

861109:SIDU RS11105
gene id: 861109:SIDU_RS11105
uniprot id: A0A1L5BQ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS09175
gene id: 861109:SIDU_RS09175
uniprot id: A0A1L5BP16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

861109:SIDU RS15945
gene id: 861109:SIDU_RS15945
uniprot id: A0A1L5BU74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

861109:SIDU RS07760
gene id: 861109:SIDU_RS07760
uniprot id: A0A1L5BNN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

861109:SIDU RS02300
gene id: 861109:SIDU_RS02300
uniprot id: A0A1L5BKJ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

861109:SIDU RS16680
gene id: 861109:SIDU_RS16680
uniprot id: A0A1L5BSW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS08200
gene id: 861109:SIDU_RS08200
uniprot id: A0A1L5BNH7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

861109:SIDU RS05270
gene id: 861109:SIDU_RS05270
uniprot id: A0A1L5BLZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

861109:SIDU RS11820
gene id: 861109:SIDU_RS11820
uniprot id: A0A1L5BQP3
names: Similarity
messages: Belongs to the ketopantoate reductase family.

861109:SIDU RS04135
gene id: 861109:SIDU_RS04135
uniprot id: A0A1L5BLP7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

861109:SIDU RS01320
gene id: 861109:SIDU_RS01320
uniprot id: A0A1L5BTI8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

861109:SIDU RS15840
gene id: 861109:SIDU_RS15840
uniprot id: A0A1L5BSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

861109:SIDU RS06505
gene id: 861109:SIDU_RS06505
uniprot id: A0A1L5BMR3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

861109:SIDU RS14690
gene id: 861109:SIDU_RS14690
uniprot id: A0A1L5BRX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

861109:SIDU RS05015
gene id: 861109:SIDU_RS05015
uniprot id: A0A1L5BMA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

861109:SIDU RS05925
gene id: 861109:SIDU_RS05925
uniprot id: A0A1L5BMR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

861109:SIDU RS12330
gene id: 861109:SIDU_RS12330
uniprot id: A0A1L5BQL4
names: Similarity
messages: Belongs to the virb1 family.

861109:SIDU RS10030
gene id: 861109:SIDU_RS10030
uniprot id: A0A1L5BPV5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS01090
gene id: 861109:SIDU_RS01090
uniprot id: A0A1L5BK09
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

861109:SIDU RS10510
gene id: 861109:SIDU_RS10510
uniprot id: A0A1L5BQ06
names: Similarity
messages: Belongs to the sterol desaturase family.

861109:SIDU RS18255
gene id: 861109:SIDU_RS18255
uniprot id: A0A1L5BUI2
names: Similarity
messages: Belongs to the transposase 7 family.

861109:SIDU RS15925
gene id: 861109:SIDU_RS15925
uniprot id: A0A1L5BSH7
names: Similarity
messages: Belongs to the peptidase M1 family.

861109:SIDU RS04185
gene id: 861109:SIDU_RS04185
uniprot id: A0A1L5BLG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

861109:SIDU RS09875
gene id: 861109:SIDU_RS09875
uniprot id: A0A1L5BPH6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

861109:SIDU RS10180
gene id: 861109:SIDU_RS10180
uniprot id: A0A1L5BPU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

861109:SIDU RS13930
gene id: 861109:SIDU_RS13930
uniprot id: A0A1L5BRF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

861109:SIDU RS05680
gene id: 861109:SIDU_RS05680
uniprot id: A0A1L5BML7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

861109:SIDU RS00615
gene id: 861109:SIDU_RS00615
uniprot id: A0A1L5BK37
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

861109:SIDU RS06520
gene id: 861109:SIDU_RS06520
uniprot id: A0A1L5BN13
names: Similarity
messages: Belongs to the thioredoxin family.

861109:SIDU RS06905
gene id: 861109:SIDU_RS06905
uniprot id: A0A1L5BMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS14895
gene id: 861109:SIDU_RS14895
uniprot id: A0A1L5BS70
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS10655
gene id: 861109:SIDU_RS10655
uniprot id: A0A1L5BPW1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

861109:SIDU RS02435
gene id: 861109:SIDU_RS02435
uniprot id: A0A1L5BTJ6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

861109:SIDU RS07400
gene id: 861109:SIDU_RS07400
uniprot id: A0A1L5BN67
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

861109:SIDU RS06395
gene id: 861109:SIDU_RS06395
uniprot id: A0A1L5BMP2
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS15535
gene id: 861109:SIDU_RS15535
uniprot id: A0A1L5BS99
names: Similarity
messages: Belongs to the Dps family.

861109:SIDU RS00360
gene id: 861109:SIDU_RS00360
uniprot id: A0A1L5BJP0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

861109:SIDU RS12365
gene id: 861109:SIDU_RS12365
uniprot id: A0A1L5BQV6
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS10500
gene id: 861109:SIDU_RS10500
uniprot id: A0A1L5BPT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

861109:SIDU RS06660
gene id: 861109:SIDU_RS06660
uniprot id: A0A1L5BN21
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

861109:SIDU RS11995
gene id: 861109:SIDU_RS11995
uniprot id: A0A1L5BQE4
names: Similarity
messages: Belongs to the UPF0229 family.

861109:SIDU RS14380
gene id: 861109:SIDU_RS14380
uniprot id: A0A1L5BRN5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

861109:SIDU RS15980
gene id: 861109:SIDU_RS15980
uniprot id: A0A1L5BSH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS09820
gene id: 861109:SIDU_RS09820
uniprot id: A0A1L5BPR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

861109:SIDU RS07410
gene id: 861109:SIDU_RS07410
uniprot id: A0A1L5BN37
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

861109:SIDU RS15590
gene id: 861109:SIDU_RS15590
uniprot id: A0A1L5BU88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

861109:SIDU RS01115
gene id: 861109:SIDU_RS01115
uniprot id: A0A1L5BK58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS17430
gene id: 861109:SIDU_RS17430
uniprot id: A0A1L5BT96
names: Similarity
messages: Belongs to the FrmR/RcnR family.

861109:SIDU RS13095
gene id: 861109:SIDU_RS13095
uniprot id: A0A1L5BR15
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

861109:SIDU RS02330
gene id: 861109:SIDU_RS02330
uniprot id: A0A1L5BKU4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

861109:SIDU RS05165
gene id: 861109:SIDU_RS05165
uniprot id: A0A1L5BLX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

861109:SIDU RS00785
gene id: 861109:SIDU_RS00785
uniprot id: A0A1L5BK68
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

861109:SIDU RS05765
gene id: 861109:SIDU_RS05765
uniprot id: A0A1L5BMN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

861109:SIDU RS08385
gene id: 861109:SIDU_RS08385
uniprot id: A0A1L5BNV7
names: Similarity
messages: Belongs to the sulfatase family.

861109:SIDU RS09100
gene id: 861109:SIDU_RS09100
uniprot id: A0A1L5BPC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

861109:SIDU RS11465
gene id: 861109:SIDU_RS11465
uniprot id: A0A1L5BQ60
names: Similarity
messages: Belongs to the GST superfamily.

861109:SIDU RS09495
gene id: 861109:SIDU_RS09495
uniprot id: A0A1L5BP69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

861109:SIDU RS05385
gene id: 861109:SIDU_RS05385
uniprot id: I5BEU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

861109:SIDU RS14340
gene id: 861109:SIDU_RS14340
uniprot id: A0A1L5BRX8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS12860
gene id: 861109:SIDU_RS12860
uniprot id: A0A1L5BR43
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

861109:SIDU RS13025
gene id: 861109:SIDU_RS13025
uniprot id: A0A1L5BR20
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS17650
gene id: 861109:SIDU_RS17650
uniprot id: A0A1L5BTC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
messages: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity). Is involved in the degradation of the important environmental pollutant gamma-hexachlorocyclohexane (gamma-HCH or lindane) as it also catalyzes conversion of 1,3,4,6-tetrachloro-1,4-cyclohexadiene (1,4-TCDN) to 2,5-dichloro-2,5-cyclohexadiene-1,4-diol (2,5-DDOL) via the intermediate 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (2,4,5-DNOL) (By similarity) (PubMed:12450824).
messages: Monomer.
messages: Periplasm

861109:SIDU RS12305
gene id: 861109:SIDU_RS12305
uniprot id: A0A1L5BU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

861109:SIDU RS09500
gene id: 861109:SIDU_RS09500
uniprot id: A0A1L5BPB2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

861109:SIDU RS00970
gene id: 861109:SIDU_RS00970
uniprot id: A0A1L5BJY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

861109:SIDU RS01555
gene id: 861109:SIDU_RS01555
uniprot id: A0A1L5BK85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

861109:SIDU RS08085
gene id: 861109:SIDU_RS08085
uniprot id: A0A1L5BNK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

861109:SIDU RS00625
gene id: 861109:SIDU_RS00625
uniprot id: I5BE33
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

861109:SIDU RS13790
gene id: 861109:SIDU_RS13790
uniprot id: A0A1L5BRE8
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

861109:SIDU RS10150
gene id: 861109:SIDU_RS10150
uniprot id: A0A1L5BPM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

861109:SIDU RS07215
gene id: 861109:SIDU_RS07215
uniprot id: A0A1L5BN55
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

861109:SIDU RS10745
gene id: 861109:SIDU_RS10745
uniprot id: A0A1L5BPT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

861109:SIDU RS04470
gene id: 861109:SIDU_RS04470
uniprot id: A0A1L5BLV7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS17850
gene id: 861109:SIDU_RS17850
uniprot id: A0A1L5BUC1
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS08350
gene id: 861109:SIDU_RS08350
uniprot id: A0A1L5BTW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

861109:SIDU RS18745
gene id: 861109:SIDU_RS18745
uniprot id: A0A1L5BUT3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

861109:SIDU RS16505
gene id: 861109:SIDU_RS16505
uniprot id: A0A1L5BSY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

861109:SIDU RS10740
gene id: 861109:SIDU_RS10740
uniprot id: A0A1L5BPS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

861109:SIDU RS14250
gene id: 861109:SIDU_RS14250
uniprot id: A0A1L5BRP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

861109:SIDU RS01300
gene id: 861109:SIDU_RS01300
uniprot id: A0A1L5BKE1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

861109:SIDU RS17410
gene id: 861109:SIDU_RS17410
uniprot id: A0A1L5BT87
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

861109:SIDU RS08430
gene id: 861109:SIDU_RS08430
uniprot id: A0A1L5BNZ0
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

861109:SIDU RS10605
gene id: 861109:SIDU_RS10605
uniprot id: A0A1L5BQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

861109:SIDU RS06460
gene id: 861109:SIDU_RS06460
uniprot id: A0A1L5BMM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS17550
gene id: 861109:SIDU_RS17550
uniprot id: A0A1L5BTB4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

861109:SIDU RS08460
gene id: 861109:SIDU_RS08460
uniprot id: A0A1L5BNS5
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS07815
gene id: 861109:SIDU_RS07815
uniprot id: A0A1L5BNF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

861109:SIDU RS05930
gene id: 861109:SIDU_RS05930
uniprot id: A0A1L5BMJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

861109:SIDU RS12870
gene id: 861109:SIDU_RS12870
uniprot id: A0A1L5BQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

861109:SIDU RS00620
gene id: 861109:SIDU_RS00620
uniprot id: A0A1L5BJS2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

861109:SIDU RS13745
gene id: 861109:SIDU_RS13745
uniprot id: A0A1L5BRC6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

861109:SIDU RS16075
gene id: 861109:SIDU_RS16075
uniprot id: A0A1L5BSJ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

861109:SIDU RS01920
gene id: 861109:SIDU_RS01920
uniprot id: A0A1L5BKP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS10055
gene id: 861109:SIDU_RS10055
uniprot id: A0A1L5BPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

861109:SIDU RS09845
gene id: 861109:SIDU_RS09845
uniprot id: A0A1L5BPR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

861109:SIDU RS02595
gene id: 861109:SIDU_RS02595
uniprot id: A0A1L5BKN7
names: Similarity
messages: Belongs to the peptidase S9C family.

861109:SIDU RS05085
gene id: 861109:SIDU_RS05085
uniprot id: A0A1L5BM50
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

861109:SIDU RS14475
gene id: 861109:SIDU_RS14475
uniprot id: A0A1L5BRQ0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

861109:SIDU RS10585
gene id: 861109:SIDU_RS10585
uniprot id: A0A1L5BPU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

861109:SIDU RS15600
gene id: 861109:SIDU_RS15600
uniprot id: A0A1L5BSB3
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

861109:SIDU RS12970
gene id: 861109:SIDU_RS12970
uniprot id: A0A1L5BR99
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

861109:SIDU RS20275
gene id: 861109:SIDU_RS20275
uniprot id: A0A1L5BR06
names: Subcellular Location Annotation
messages: Cytoplasm

861109:SIDU RS11135
gene id: 861109:SIDU_RS11135
uniprot id: A0A1L5BQ08
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

861109:SIDU RS01800
gene id: 861109:SIDU_RS01800
uniprot id: A0A1L5BKM0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS15750
gene id: 861109:SIDU_RS15750
uniprot id: A0A1L5BSD4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

861109:SIDU RS11315
gene id: 861109:SIDU_RS11315
uniprot id: A0A1L5BQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

861109:SIDU RS07810
gene id: 861109:SIDU_RS07810
uniprot id: A0A1L5BNP5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

861109:SIDU RS13130
gene id: 861109:SIDU_RS13130
uniprot id: A0A1L5BR38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

861109:SIDU RS09405
gene id: 861109:SIDU_RS09405
uniprot id: A0A1L5BP82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS09965
gene id: 861109:SIDU_RS09965
uniprot id: A0A1L5BPC6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

861109:SIDU RS10515
gene id: 861109:SIDU_RS10515
uniprot id: A0A1L5BPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

861109:SIDU RS13765
gene id: 861109:SIDU_RS13765
uniprot id: A0A1L5BRG5
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

861109:SIDU RS17440
gene id: 861109:SIDU_RS17440
uniprot id: A0A1L5BTA9
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

861109:SIDU RS04040
gene id: 861109:SIDU_RS04040
uniprot id: A0A1L5BLD6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

861109:SIDU RS03425
gene id: 861109:SIDU_RS03425
uniprot id: A0A1L5BLF2
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

861109:SIDU RS14815
gene id: 861109:SIDU_RS14815
uniprot id: A0A1L5BRZ1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

861109:SIDU RS09850
gene id: 861109:SIDU_RS09850
uniprot id: A0A1L5BPN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861109:SIDU RS02950
gene id: 861109:SIDU_RS02950
uniprot id: A0A1L5BKV7
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

861109:SIDU RS04985
gene id: 861109:SIDU_RS04985
uniprot id: A0A1L5BLU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

861109:SIDU RS05745
gene id: 861109:SIDU_RS05745
uniprot id: A0A1L5BME7
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

861109:SIDU RS09040
gene id: 861109:SIDU_RS09040
uniprot id: A0A1L5BNV6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

861109:SIDU RS07020
gene id: 861109:SIDU_RS07020
uniprot id: A0A1L5BTS6
names: Similarity
messages: Belongs to the histone deacetylase family.

861109:SIDU RS12855
gene id: 861109:SIDU_RS12855
uniprot id: A0A1L5BR79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

861109:SIDU RS00910
gene id: 861109:SIDU_RS00910
uniprot id: A0A1L5BJX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS17855
gene id: 861109:SIDU_RS17855
uniprot id: A0A1L5BUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

861109:SIDU RS10145
gene id: 861109:SIDU_RS10145
uniprot id: A0A1L5BPX3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

861109:SIDU RS04860
gene id: 861109:SIDU_RS04860
uniprot id: A0A1L5BLS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

861109:SIDU RS03135
gene id: 861109:SIDU_RS03135
uniprot id: A0A1L5BL72
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

861109:SIDU RS04440
gene id: 861109:SIDU_RS04440
uniprot id: I5B8R0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

861109:SIDU RS18435
gene id: 861109:SIDU_RS18435
uniprot id: A0A1L5BUN8
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS03070
gene id: 861109:SIDU_RS03070
uniprot id: A0A1L5BL21
names: Similarity
messages: Belongs to the Skp family.

861109:SIDU RS10385
gene id: 861109:SIDU_RS10385
uniprot id: A0A1L5BPY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

861109:SIDU RS17330
gene id: 861109:SIDU_RS17330
uniprot id: A0A1L5BT71
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

861109:SIDU RS10035
gene id: 861109:SIDU_RS10035
uniprot id: A0A1L5BTY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

861109:SIDU RS14795
gene id: 861109:SIDU_RS14795
uniprot id: A0A1L5BRW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS16270
gene id: 861109:SIDU_RS16270
uniprot id: A0A1L5BSP3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

861109:SIDU RS15855
gene id: 861109:SIDU_RS15855
uniprot id: A0A1L5BU67
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

861109:SIDU RS08940
gene id: 861109:SIDU_RS08940
uniprot id: A0A1L5BNV5
names: Similarity
messages: Belongs to the manganese catalase family.

861109:SIDU RS07765
gene id: 861109:SIDU_RS07765
uniprot id: A0A1L5BNE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

861109:SIDU RS16665
gene id: 861109:SIDU_RS16665
uniprot id: A0A1L5BT18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

861109:SIDU RS10050
gene id: 861109:SIDU_RS10050
uniprot id: A0A1L5BPG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

861109:SIDU RS01030
gene id: 861109:SIDU_RS01030
uniprot id: A0A1L5BK00
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

861109:SIDU RS06745
gene id: 861109:SIDU_RS06745
uniprot id: A0A1L5BMY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

861109:SIDU RS01700
gene id: 861109:SIDU_RS01700
uniprot id: A0A1L5BKM6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

861109:SIDU RS17200
gene id: 861109:SIDU_RS17200
uniprot id: A0A1L5BT59
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

861109:SIDU RS10855
gene id: 861109:SIDU_RS10855
uniprot id: A0A1L5BPW0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

861109:SIDU RS09755
gene id: 861109:SIDU_RS09755
uniprot id: A0A1L5BPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

861109:SIDU RS18190
gene id: 861109:SIDU_RS18190
uniprot id: A0A1L5BUG3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS12690
gene id: 861109:SIDU_RS12690
uniprot id: A0A1L5BU73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS15035
gene id: 861109:SIDU_RS15035
uniprot id: A0A1L5BS28
names: Similarity
messages: Belongs to the peptidase M13 family.

861109:SIDU RS10280
gene id: 861109:SIDU_RS10280
uniprot id: A0A1L5BPW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

861109:SIDU RS14235
gene id: 861109:SIDU_RS14235
uniprot id: A0A1L5BRN0
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

861109:SIDU RS06045
gene id: 861109:SIDU_RS06045
uniprot id: A0A1L5BMF6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

861109:SIDU RS08455
gene id: 861109:SIDU_RS08455
uniprot id: A0A1L5BP09
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

861109:SIDU RS12815
gene id: 861109:SIDU_RS12815
uniprot id: A0A1L5BQY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

861109:SIDU RS00840
gene id: 861109:SIDU_RS00840
uniprot id: A0A1L5BTG4
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

861109:SIDU RS11380
gene id: 861109:SIDU_RS11380
uniprot id: A0A1L5BQF4
names: Similarity
messages: Belongs to the cytochrome P450 family.

861109:SIDU RS04320
gene id: 861109:SIDU_RS04320
uniprot id: A0A1L5BLT5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS04995
gene id: 861109:SIDU_RS04995
uniprot id: A0A1L5BLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

861109:SIDU RS15480
gene id: 861109:SIDU_RS15480
uniprot id: A0A1L5BSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

861109:SIDU RS03250
gene id: 861109:SIDU_RS03250
uniprot id: A0A1L5BLB8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

861109:SIDU RS07405
gene id: 861109:SIDU_RS07405
uniprot id: A0A1L5BN03
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS01510
gene id: 861109:SIDU_RS01510
uniprot id: A0A1L5BK74
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

861109:SIDU RS01425
gene id: 861109:SIDU_RS01425
uniprot id: A0A1L5BK59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

861109:SIDU RS03090
gene id: 861109:SIDU_RS03090
uniprot id: A0A1L5BL88
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS05170
gene id: 861109:SIDU_RS05170
uniprot id: A0A1L5BLX7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

861109:SIDU RS18955
gene id: 861109:SIDU_RS18955
uniprot id: A0A1L5BUY1
names: Similarity
messages: Belongs to the MobA/MobL family.

861109:SIDU RS05060
gene id: 861109:SIDU_RS05060
uniprot id: A0A1L5BM05
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS09945
gene id: 861109:SIDU_RS09945
uniprot id: A0A1L5BPS9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

861109:SIDU RS13125
gene id: 861109:SIDU_RS13125
uniprot id: A0A1L5BR14
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

861109:SIDU RS07770
gene id: 861109:SIDU_RS07770
uniprot id: A0A1L5BNA9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

861109:SIDU RS14820
gene id: 861109:SIDU_RS14820
uniprot id: A0A1L5BU62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

861109:SIDU RS11285
gene id: 861109:SIDU_RS11285
uniprot id: A0A1L5BQH3
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS12935
gene id: 861109:SIDU_RS12935
uniprot id: A0A1L5BQY1
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

861109:SIDU RS16525
gene id: 861109:SIDU_RS16525
uniprot id: A0A1L5BSR8
names: Similarity
messages: Belongs to the PspA/IM30 family.

861109:SIDU RS10705
gene id: 861109:SIDU_RS10705
uniprot id: A0A1L5BPW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

861109:SIDU RS11160
gene id: 861109:SIDU_RS11160
uniprot id: A0A1L5BQ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

861109:SIDU RS02140
gene id: 861109:SIDU_RS02140
uniprot id: A0A1L5BKU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

861109:SIDU RS09055
gene id: 861109:SIDU_RS09055
uniprot id: A0A1L5BP26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

861109:SIDU RS02455
gene id: 861109:SIDU_RS02455
uniprot id: A0A1L5BKL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

861109:SIDU RS14945
gene id: 861109:SIDU_RS14945
uniprot id: A0A1L5BS80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

861109:SIDU RS10725
gene id: 861109:SIDU_RS10725
uniprot id: A0A1L5BQ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

861109:SIDU RS10590
gene id: 861109:SIDU_RS10590
uniprot id: A0A1L5BPQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

861109:SIDU RS09345
gene id: 861109:SIDU_RS09345
uniprot id: A0A1L5BPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS10295
gene id: 861109:SIDU_RS10295
uniprot id: A0A1L5BPK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

861109:SIDU RS05525
gene id: 861109:SIDU_RS05525
uniprot id: A0A1L5BM81
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

861109:SIDU RS00905
gene id: 861109:SIDU_RS00905
uniprot id: A0A1L5BK88
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS02065
gene id: 861109:SIDU_RS02065
uniprot id: A0A1L5BKK4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

861109:SIDU RS04805
gene id: 861109:SIDU_RS04805
uniprot id: A0A1L5BTQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

861109:SIDU RS10285
gene id: 861109:SIDU_RS10285
uniprot id: A0A1L5BPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

861109:SIDU RS13420
gene id: 861109:SIDU_RS13420
uniprot id: A0A1L5BRH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

861109:SIDU RS06455
gene id: 861109:SIDU_RS06455
uniprot id: A0A1L5BMH5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

861109:SIDU RS02915
gene id: 861109:SIDU_RS02915
uniprot id: A0A1L5BL39
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

861109:SIDU RS04710
gene id: 861109:SIDU_RS04710
uniprot id: A0A1L5BLR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

861109:SIDU RS02655
gene id: 861109:SIDU_RS02655
uniprot id: A0A1L5BTJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS13865
gene id: 861109:SIDU_RS13865
uniprot id: A0A1L5BRE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

861109:SIDU RS10665
gene id: 861109:SIDU_RS10665
uniprot id: A0A1L5BQ32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

861109:SIDU RS04365
gene id: 861109:SIDU_RS04365
uniprot id: A0A1L5BLX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

861109:SIDU RS03965
gene id: 861109:SIDU_RS03965
uniprot id: A0A1L5BLL7
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS15540
gene id: 861109:SIDU_RS15540
uniprot id: A0A1L5BSA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

861109:SIDU RS02105
gene id: 861109:SIDU_RS02105
uniprot id: A0A1L5BTJ0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

861109:SIDU RS04265
gene id: 861109:SIDU_RS04265
uniprot id: A0A1L5BLL8
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS07705
gene id: 861109:SIDU_RS07705
uniprot id: A0A1L5BND7
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

861109:SIDU RS05050
gene id: 861109:SIDU_RS05050
uniprot id: A0A1L5BLV6
names: Similarity
messages: Belongs to the bacterial glucokinase family.

861109:SIDU RS00600
gene id: 861109:SIDU_RS00600
uniprot id: A0A1L5BJX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

861109:SIDU RS00940
gene id: 861109:SIDU_RS00940
uniprot id: A0A1L5BK31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

861109:SIDU RS14255
gene id: 861109:SIDU_RS14255
uniprot id: A0A1L5BRM2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

861109:SIDU RS03110
gene id: 861109:SIDU_RS03110
uniprot id: A0A1L5BKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

861109:SIDU RS17425
gene id: 861109:SIDU_RS17425
uniprot id: A0A1L5BTD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

861109:SIDU RS18465
gene id: 861109:SIDU_RS18465
uniprot id: A0A1L5BUN6
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

861109:SIDU RS12010
gene id: 861109:SIDU_RS12010
uniprot id: A0A1L5BQI3
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

861109:SIDU RS18075
gene id: 861109:SIDU_RS18075
uniprot id: A0A1L5BUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

861109:SIDU RS02475
gene id: 861109:SIDU_RS02475
uniprot id: A0A1L5BKS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

861109:SIDU RS00230
gene id: 861109:SIDU_RS00230
uniprot id: A0A1L5BJU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

861109:SIDU RS03055
gene id: 861109:SIDU_RS03055
uniprot id: A0A1L5BKX8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS13920
gene id: 861109:SIDU_RS13920
uniprot id: A0A1L5BRG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

861109:SIDU RS02375
gene id: 861109:SIDU_RS02375
uniprot id: A0A1L5BKK8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861109:SIDU RS02180
gene id: 861109:SIDU_RS02180
uniprot id: A0A1L5BKH3
names: Similarity
messages: Belongs to the DapA family.

861109:SIDU RS09510
gene id: 861109:SIDU_RS09510
uniprot id: A0A1L5BPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

861109:SIDU RS13905
gene id: 861109:SIDU_RS13905
uniprot id: A0A1L5BRE9
names: Similarity
messages: Belongs to the UPF0335 family.

861109:SIDU RS14305
gene id: 861109:SIDU_RS14305
uniprot id: A0A1L5BRN6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

861109:SIDU RS14280
gene id: 861109:SIDU_RS14280
uniprot id: A0A1L5BRL4
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

861109:SIDU RS12985
gene id: 861109:SIDU_RS12985
uniprot id: A0A1L5BQZ5
names: Similarity
messages: Belongs to the MotB family.

861109:SIDU RS02900
gene id: 861109:SIDU_RS02900
uniprot id: A0A1L5BKZ0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS03080
gene id: 861109:SIDU_RS03080
uniprot id: A0A1L5BKY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

861109:SIDU RS05345
gene id: 861109:SIDU_RS05345
uniprot id: A0A1L5BMF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

861109:SIDU RS06650
gene id: 861109:SIDU_RS06650
uniprot id: A0A1L5BMV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

861109:SIDU RS18540
gene id: 861109:SIDU_RS18540
uniprot id: A0A1L5BUP7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

861109:SIDU RS01535
gene id: 861109:SIDU_RS01535
uniprot id: A0A1L5BK82
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS03205
gene id: 861109:SIDU_RS03205
uniprot id: A0A1L5BL44
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

861109:SIDU RS00305
gene id: 861109:SIDU_RS00305
uniprot id: A0A1L5BJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS05215
gene id: 861109:SIDU_RS05215
uniprot id: A0A1L5BLY3
names: Similarity
messages: Belongs to the ros/MucR family.

861109:SIDU RS04035
gene id: 861109:SIDU_RS04035
uniprot id: A0A1L5BLD8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

861109:SIDU RS00560
gene id: 861109:SIDU_RS00560
uniprot id: A0A1L5BJR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

861109:SIDU RS07295
gene id: 861109:SIDU_RS07295
uniprot id: A0A1L5BMY0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS07345
gene id: 861109:SIDU_RS07345
uniprot id: A0A1L5BN54
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

861109:SIDU RS12185
gene id: 861109:SIDU_RS12185
uniprot id: A0A1L5BQT0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

861109:SIDU RS00445
gene id: 861109:SIDU_RS00445
uniprot id: A0A1L5BJP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

861109:SIDU RS01125
gene id: 861109:SIDU_RS01125
uniprot id: A0A1L5BKB4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861109:SIDU RS04625
gene id: 861109:SIDU_RS04625
uniprot id: A0A1L5BLN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

861109:SIDU RS00720
gene id: 861109:SIDU_RS00720
uniprot id: A0A1L5BK47
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

861109:SIDU RS05140
gene id: 861109:SIDU_RS05140
uniprot id: A0A1L5BM60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS11965
gene id: 861109:SIDU_RS11965
uniprot id: A0A1L5BQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS09905
gene id: 861109:SIDU_RS09905
uniprot id: A0A1L5BPH0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

861109:SIDU RS01960
gene id: 861109:SIDU_RS01960
uniprot id: A0A1L5BTI4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

861109:SIDU RS16170
gene id: 861109:SIDU_RS16170
uniprot id: A0A1L5BSK9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

861109:SIDU RS09880
gene id: 861109:SIDU_RS09880
uniprot id: A0A1L5BPC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

861109:SIDU RS12180
gene id: 861109:SIDU_RS12180
uniprot id: A0A1L5BQV8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS10820
gene id: 861109:SIDU_RS10820
uniprot id: A0A1L5BPZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

861109:SIDU RS00165
gene id: 861109:SIDU_RS00165
uniprot id: A0A1L5BJL3
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS18390
gene id: 861109:SIDU_RS18390
uniprot id: A0A1L5BUM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

861109:SIDU RS06775
gene id: 861109:SIDU_RS06775
uniprot id: A0A1L5BMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

861109:SIDU RS12750
gene id: 861109:SIDU_RS12750
uniprot id: A0A1L5BR58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

861109:SIDU RS09465
gene id: 861109:SIDU_RS09465
uniprot id: A0A1L5BP39
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS07840
gene id: 861109:SIDU_RS07840
uniprot id: A0A1L5BNL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

861109:SIDU RS14755
gene id: 861109:SIDU_RS14755
uniprot id: A0A1L5BRW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

861109:SIDU RS10815
gene id: 861109:SIDU_RS10815
uniprot id: A0A1L5BPV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

861109:SIDU RS05045
gene id: 861109:SIDU_RS05045
uniprot id: A0A1L5BTR1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

861109:SIDU RS16060
gene id: 861109:SIDU_RS16060
uniprot id: A0A1L5BSS3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

861109:SIDU RS00505
gene id: 861109:SIDU_RS00505
uniprot id: A0A1L5BJQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

861109:SIDU RS11890
gene id: 861109:SIDU_RS11890
uniprot id: A0A1L5BQC3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

861109:SIDU RS11010
gene id: 861109:SIDU_RS11010
uniprot id: A0A1L5BQB6
names: Similarity
messages: Belongs to the GSP E family.

861109:SIDU RS11530
gene id: 861109:SIDU_RS11530
uniprot id: A0A1L5BQK9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

861109:SIDU RS09910
gene id: 861109:SIDU_RS09910
uniprot id: A0A1L5BPB8
names: Function
messages: Acts on leucine, isoleucine and valine.

861109:SIDU RS08960
gene id: 861109:SIDU_RS08960
uniprot id: A0A1L5BNX2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

861109:SIDU RS18195
gene id: 861109:SIDU_RS18195
uniprot id: A0A1L5BQK9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

861109:SIDU RS13445
gene id: 861109:SIDU_RS13445
uniprot id: I5BA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

861109:SIDU RS01270
gene id: 861109:SIDU_RS01270
uniprot id: A0A1L5BK39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

861109:SIDU RS07445
gene id: 861109:SIDU_RS07445
uniprot id: A0A1L5BNG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS16585
gene id: 861109:SIDU_RS16585
uniprot id: A0A1L5BSU9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

861109:SIDU RS02360
gene id: 861109:SIDU_RS02360
uniprot id: A0A1L5BKY2
names: Cofactor
names: Function
messages: Alkaline phosphatase with broad substrate specificity.
messages: Binds 2 Zn(2+) ions.

861109:SIDU RS03010
gene id: 861109:SIDU_RS03010
uniprot id: I5BFX0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

861109:SIDU RS02875
gene id: 861109:SIDU_RS02875
uniprot id: A0A1L5BKU8
names: Similarity
messages: Belongs to the bacterial secretin family.

861109:SIDU RS17435
gene id: 861109:SIDU_RS17435
uniprot id: A0A1L5BT99
names: Similarity
messages: Belongs to the lycopene cyclase family.

861109:SIDU RS06965
gene id: 861109:SIDU_RS06965
uniprot id: A0A1L5BN04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

861109:SIDU RS12705
gene id: 861109:SIDU_RS12705
uniprot id: A0A1L5BR13
names: Cofactor
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

861109:SIDU RS10520
gene id: 861109:SIDU_RS10520
uniprot id: A0A1L5BPM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

861109:SIDU RS07940
gene id: 861109:SIDU_RS07940
uniprot id: A0A1L5BND9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS13035
gene id: 861109:SIDU_RS13035
uniprot id: A0A1L5BR73
names: Similarity
messages: Belongs to the UPF0111 family.

861109:SIDU RS14790
gene id: 861109:SIDU_RS14790
uniprot id: A0A1L5BRV6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS13580
gene id: 861109:SIDU_RS13580
uniprot id: A0A1L5BRC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

861109:SIDU RS06720
gene id: 861109:SIDU_RS06720
uniprot id: A0A1L5BMS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS11825
gene id: 861109:SIDU_RS11825
uniprot id: A0A1L5BQL8
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS18890
gene id: 861109:SIDU_RS18890
uniprot id: A0A1L5BUW8
names: Similarity
messages: Belongs to the YciI family.

861109:SIDU RS10770
gene id: 861109:SIDU_RS10770
uniprot id: A0A1L5BPY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

861109:SIDU RS08065
gene id: 861109:SIDU_RS08065
uniprot id: A0A1L5BNT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

861109:SIDU RS01625
gene id: 861109:SIDU_RS01625
uniprot id: A0A1L5BK95
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

861109:SIDU RS07365
gene id: 861109:SIDU_RS07365
uniprot id: A0A1L5BNG5
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

861109:SIDU RS13045
gene id: 861109:SIDU_RS13045
uniprot id: A0A1L5BR05
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

861109:SIDU RS00215
gene id: 861109:SIDU_RS00215
uniprot id: A0A1L5BTE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

861109:SIDU RS06880
gene id: 861109:SIDU_RS06880
uniprot id: A0A1L5BN59
names: Similarity
messages: Belongs to the UPF0262 family.

861109:SIDU RS07315
gene id: 861109:SIDU_RS07315
uniprot id: A0A1L5BN23
names: Subcellular Location Annotation
messages: Nucleus

861109:SIDU RS04920
gene id: 861109:SIDU_RS04920
uniprot id: A0A1L5BLT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS09205
gene id: 861109:SIDU_RS09205
uniprot id: A0A1L5BP14
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

861109:SIDU RS18575
gene id: 861109:SIDU_RS18575
uniprot id: A0A1L5BUQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

861109:SIDU RS09080
gene id: 861109:SIDU_RS09080
uniprot id: A0A1L5BP87
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

861109:SIDU RS01025
gene id: 861109:SIDU_RS01025
uniprot id: A0A1L5BJZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS16450
gene id: 861109:SIDU_RS16450
uniprot id: A0A1L5BST5
names: Similarity
messages: Belongs to the peptidase M16 family.

861109:SIDU RS00585
gene id: 861109:SIDU_RS00585
uniprot id: A0A1L5BJZ9
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS02780
gene id: 861109:SIDU_RS02780
uniprot id: A0A1L5BKT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

861109:SIDU RS05125
gene id: 861109:SIDU_RS05125
uniprot id: A0A1L5BM14
names: Similarity
messages: Belongs to the HIBADH-related family.

861109:SIDU RS14190
gene id: 861109:SIDU_RS14190
uniprot id: A0A1L5BRL1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS15370
gene id: 861109:SIDU_RS15370
uniprot id: A0A1L5BS74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS12295
gene id: 861109:SIDU_RS12295
uniprot id: A0A1L5BQN5
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS03005
gene id: 861109:SIDU_RS03005
uniprot id: I5BFW9
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

861109:SIDU RS03060
gene id: 861109:SIDU_RS03060
uniprot id: A0A1L5BKX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

861109:SIDU RS17875
gene id: 861109:SIDU_RS17875
uniprot id: A0A1L5BUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

861109:SIDU RS17565
gene id: 861109:SIDU_RS17565
uniprot id: A0A1L5BTK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS11025
gene id: 861109:SIDU_RS11025
uniprot id: A0A1L5BPX1
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS03405
gene id: 861109:SIDU_RS03405
uniprot id: A0A1L5BL77
names: Similarity
messages: Belongs to the virb1 family.

861109:SIDU RS08210
gene id: 861109:SIDU_RS08210
uniprot id: A0A1L5BNM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

861109:SIDU RS00900
gene id: 861109:SIDU_RS00900
uniprot id: A0A1L5BK75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

861109:SIDU RS14470
gene id: 861109:SIDU_RS14470
uniprot id: A0A1L5BRR4
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

861109:SIDU RS00755
gene id: 861109:SIDU_RS00755
uniprot id: A0A1L5BJV8
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

861109:SIDU RS12930
gene id: 861109:SIDU_RS12930
uniprot id: A0A1L5BQY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

861109:SIDU RS17345
gene id: 861109:SIDU_RS17345
uniprot id: A0A1L5BTG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

861109:SIDU RS00575
gene id: 861109:SIDU_RS00575
uniprot id: A0A1L5BJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

861109:SIDU RS16175
gene id: 861109:SIDU_RS16175
uniprot id: A0A1L5BSU4
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

861109:SIDU RS13590
gene id: 861109:SIDU_RS13590
uniprot id: A0A1L5BRH2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

861109:SIDU RS01505
gene id: 861109:SIDU_RS01505
uniprot id: A0A1L5BK77
names: Similarity
messages: Belongs to the HesB/IscA family.

861109:SIDU RS15430
gene id: 861109:SIDU_RS15430
uniprot id: A0A1L5BU69
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

861109:SIDU RS09695
gene id: 861109:SIDU_RS09695
uniprot id: A0A1L5BP93
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

861109:SIDU RS01120
gene id: 861109:SIDU_RS01120
uniprot id: A0A1L5BK13
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS08665
gene id: 861109:SIDU_RS08665
uniprot id: A0A1L5BNT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

861109:SIDU RS00800
gene id: 861109:SIDU_RS00800
uniprot id: A0A1L5BJW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

861109:SIDU RS18655
gene id: 861109:SIDU_RS18655
uniprot id: A0A1L5BUT2
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

861109:SIDU RS12430
gene id: 861109:SIDU_RS12430
uniprot id: A0A1L5BQM6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

861109:SIDU RS16380
gene id: 861109:SIDU_RS16380
uniprot id: A0A1L5BSR1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

861109:SIDU RS17245
gene id: 861109:SIDU_RS17245
uniprot id: A0A1L5BT83
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

861109:SIDU RS17445
gene id: 861109:SIDU_RS17445
uniprot id: A0A1L5BTB8
names: Similarity
messages: Belongs to the LOG family.

861109:SIDU RS04385
gene id: 861109:SIDU_RS04385
uniprot id: A0A1L5BLJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS07085
gene id: 861109:SIDU_RS07085
uniprot id: A0A1L5BNB3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

861109:SIDU RS11230
gene id: 861109:SIDU_RS11230
uniprot id: A0A1L5BQ52
names: Similarity
messages: Belongs to the ros/MucR family.

861109:SIDU RS13245
gene id: 861109:SIDU_RS13245
uniprot id: A0A1L5BR61
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

861109:SIDU RS15160
gene id: 861109:SIDU_RS15160
uniprot id: I5BEI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

861109:SIDU RS11885
gene id: 861109:SIDU_RS11885
uniprot id: A0A1L5BQF7
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS15220
gene id: 861109:SIDU_RS15220
uniprot id: I5BB79
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

861109:SIDU RS12415
gene id: 861109:SIDU_RS12415
uniprot id: A0A1L5BQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Periplasm

861109:SIDU RS17535
gene id: 861109:SIDU_RS17535
uniprot id: A0A1L5BTA6
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

861109:SIDU RS18815
gene id: 861109:SIDU_RS18815
uniprot id: A0A1L5BUV5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

861109:SIDU RS00295
gene id: 861109:SIDU_RS00295
uniprot id: A0A1L5BJV0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

861109:SIDU RS13335
gene id: 861109:SIDU_RS13335
uniprot id: A0A1L5BR49
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

861109:SIDU RS05355
gene id: 861109:SIDU_RS05355
uniprot id: I5BET6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

861109:SIDU RS01155
gene id: 861109:SIDU_RS01155
uniprot id: A0A1L5BTI5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

861109:SIDU RS01265
gene id: 861109:SIDU_RS01265
uniprot id: A0A1L5BK41
names: Similarity
messages: Belongs to the DEAD box helicase family.

861109:SIDU RS14635
gene id: 861109:SIDU_RS14635
uniprot id: A0A1L5BRU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS03350
gene id: 861109:SIDU_RS03350
uniprot id: A0A1L5BL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS01440
gene id: 861109:SIDU_RS01440
uniprot id: A0A1L5BKA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

861109:SIDU RS16490
gene id: 861109:SIDU_RS16490
uniprot id: A0A1L5BU85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

861109:SIDU RS04675
gene id: 861109:SIDU_RS04675
uniprot id: A0A1L5BLT2
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

861109:SIDU RS05920
gene id: 861109:SIDU_RS05920
uniprot id: A0A1L5BMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

861109:SIDU RS17365
gene id: 861109:SIDU_RS17365
uniprot id: A0A1L5BT76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

861109:SIDU RS08695
gene id: 861109:SIDU_RS08695
uniprot id: A0A1L5BNS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS17225
gene id: 861109:SIDU_RS17225
uniprot id: A0A1L5BT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS14095
gene id: 861109:SIDU_RS14095
uniprot id: A0A1L5BRS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

861109:SIDU RS13600
gene id: 861109:SIDU_RS13600
uniprot id: A0A1L5BRA5
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

861109:SIDU RS09555
gene id: 861109:SIDU_RS09555
uniprot id: A0A1L5BPC2
names: Similarity
messages: Belongs to the CcdB toxin family.

861109:SIDU RS00945
gene id: 861109:SIDU_RS00945
uniprot id: A0A1L5BJY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

861109:SIDU RS15960
gene id: 861109:SIDU_RS15960
uniprot id: A0A1L5BSH4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

861109:SIDU RS05570
gene id: 861109:SIDU_RS05570
uniprot id: A0A1L5BMB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

861109:SIDU RS01145
gene id: 861109:SIDU_RS01145
uniprot id: I5BFN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

861109:SIDU RS04680
gene id: 861109:SIDU_RS04680
uniprot id: A0A1L5BLP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS16660
gene id: 861109:SIDU_RS16660
uniprot id: A0A1L5BU77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

861109:SIDU RS15190
gene id: 861109:SIDU_RS15190
uniprot id: I5BB85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS04910
gene id: 861109:SIDU_RS04910
uniprot id: A0A1L5BLX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS00540
gene id: 861109:SIDU_RS00540
uniprot id: A0A1L5BJW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

861109:SIDU RS09540
gene id: 861109:SIDU_RS09540
uniprot id: A0A1L5BPB3
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

861109:SIDU RS04520
gene id: 861109:SIDU_RS04520
uniprot id: A0A1L5BLN2
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

861109:SIDU RS01235
gene id: 861109:SIDU_RS01235
uniprot id: A0A1L5BK79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS14145
gene id: 861109:SIDU_RS14145
uniprot id: A0A1L5BRT5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

861109:SIDU RS12790
gene id: 861109:SIDU_RS12790
uniprot id: A0A1L5BQV3
names: Similarity
messages: Belongs to the type III secretion exporter family.

861109:SIDU RS06345
gene id: 861109:SIDU_RS06345
uniprot id: A0A1L5BMK5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

861109:SIDU RS07870
gene id: 861109:SIDU_RS07870
uniprot id: A0A1L5BNC9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS07710
gene id: 861109:SIDU_RS07710
uniprot id: A0A1L5BN99
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

861109:SIDU RS15050
gene id: 861109:SIDU_RS15050
uniprot id: I5BBB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

861109:SIDU RS02010
gene id: 861109:SIDU_RS02010
uniprot id: A0A1L5BKE5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861109:SIDU RS04180
gene id: 861109:SIDU_RS04180
uniprot id: A0A1L5BLK6
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

861109:SIDU RS12715
gene id: 861109:SIDU_RS12715
uniprot id: A0A1L5BQT9
names: Subunit
messages: Homodimer.

861109:SIDU RS08410
gene id: 861109:SIDU_RS08410
uniprot id: A0A1L5BNR4
names: Similarity
messages: Belongs to the TmoD/XamoD family.

861109:SIDU RS05155
gene id: 861109:SIDU_RS05155
uniprot id: A0A1L5BM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS01445
gene id: 861109:SIDU_RS01445
uniprot id: A0A1L5BTL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

861109:SIDU RS16420
gene id: 861109:SIDU_RS16420
uniprot id: A0A1L5BSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

861109:SIDU RS02845
gene id: 861109:SIDU_RS02845
uniprot id: A0A1L5BKU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

861109:SIDU RS08240
gene id: 861109:SIDU_RS08240
uniprot id: A0A1L5BNW4
names: Similarity
messages: Belongs to the peptidase C40 family.

861109:SIDU RS07060
gene id: 861109:SIDU_RS07060
uniprot id: A0A1L5BNA6
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

861109:SIDU RS03895
gene id: 861109:SIDU_RS03895
uniprot id: A0A1L5BLC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

861109:SIDU RS11940
gene id: 861109:SIDU_RS11940
uniprot id: A0A1L5BQD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

861109:SIDU RS15555
gene id: 861109:SIDU_RS15555
uniprot id: A0A1L5BSA4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

861109:SIDU RS07875
gene id: 861109:SIDU_RS07875
uniprot id: I5BH53
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

861109:SIDU RS02945
gene id: 861109:SIDU_RS02945
uniprot id: A0A1L5BKV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

861109:SIDU RS15860
gene id: 861109:SIDU_RS15860
uniprot id: A0A1L5BSF6
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

861109:SIDU RS04345
gene id: 861109:SIDU_RS04345
uniprot id: A0A1L5BLN9
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS12700
gene id: 861109:SIDU_RS12700
uniprot id: A0A1L5BR50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

861109:SIDU RS16085
gene id: 861109:SIDU_RS16085
uniprot id: A0A1L5BSJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

861109:SIDU RS05335
gene id: 861109:SIDU_RS05335
uniprot id: I5BET2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

861109:SIDU RS06890
gene id: 861109:SIDU_RS06890
uniprot id: A0A1L5BMR1
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

861109:SIDU RS05850
gene id: 861109:SIDU_RS05850
uniprot id: A0A1L5BMC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS05415
gene id: 861109:SIDU_RS05415
uniprot id: A0A1L5BM31
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

861109:SIDU RS09125
gene id: 861109:SIDU_RS09125
uniprot id: A0A1L5BP42
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

861109:SIDU RS08215
gene id: 861109:SIDU_RS08215
uniprot id: A0A1L5BNU6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

861109:SIDU RS07425
gene id: 861109:SIDU_RS07425
uniprot id: A0A1L5BN49
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS06430
gene id: 861109:SIDU_RS06430
uniprot id: A0A1L5BMN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

861109:SIDU RS03910
gene id: 861109:SIDU_RS03910
uniprot id: A0A1L5BLP2
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

861109:SIDU RS01845
gene id: 861109:SIDU_RS01845
uniprot id: A0A1L5BKC9
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

861109:SIDU RS02995
gene id: 861109:SIDU_RS02995
uniprot id: A0A1L5BL13
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS09210
gene id: 861109:SIDU_RS09210
uniprot id: A0A1L5BPG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

861109:SIDU RS00640
gene id: 861109:SIDU_RS00640
uniprot id: I5BB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

861109:SIDU RS09025
gene id: 861109:SIDU_RS09025
uniprot id: A0A1L5BP74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

861109:SIDU RS08595
gene id: 861109:SIDU_RS08595
uniprot id: A0A1L5BNQ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

861109:SIDU RS11170
gene id: 861109:SIDU_RS11170
uniprot id: A0A1L5BQ10
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861109:SIDU RS15030
gene id: 861109:SIDU_RS15030
uniprot id: A0A1L5BS61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS03485
gene id: 861109:SIDU_RS03485
uniprot id: A0A1L5BL95
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS16395
gene id: 861109:SIDU_RS16395
uniprot id: A0A1L5BSS2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

861109:SIDU RS05200
gene id: 861109:SIDU_RS05200
uniprot id: A0A1L5BMD8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

861109:SIDU RS01405
gene id: 861109:SIDU_RS01405
uniprot id: A0A1L5BK63
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

861109:SIDU RS02485
gene id: 861109:SIDU_RS02485
uniprot id: A0A1L5BTS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

861109:SIDU RS04000
gene id: 861109:SIDU_RS04000
uniprot id: A0A1L5BLI0
names: Function
messages: Multidrug efflux pump.

861109:SIDU RS02695
gene id: 861109:SIDU_RS02695
uniprot id: A0A1L5BKW1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

861109:SIDU RS14365
gene id: 861109:SIDU_RS14365
uniprot id: A0A1L5BRM9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

861109:SIDU RS16355
gene id: 861109:SIDU_RS16355
uniprot id: A0A1L5BSQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

861109:SIDU RS05295
gene id: 861109:SIDU_RS05295
uniprot id: A0A1L5BM59
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

861109:SIDU RS04830
gene id: 861109:SIDU_RS04830
uniprot id: A0A1L5BLT0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

861109:SIDU RS01000
gene id: 861109:SIDU_RS01000
uniprot id: A0A1L5BK40
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

861109:SIDU RS14970
gene id: 861109:SIDU_RS14970
uniprot id: A0A1L5BS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

861109:SIDU RS11725
gene id: 861109:SIDU_RS11725
uniprot id: I5B918
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

861109:SIDU RS16945
gene id: 861109:SIDU_RS16945
uniprot id: A0A1L5BT20
names: Similarity
messages: Belongs to the virb1 family.

861109:SIDU RS10320
gene id: 861109:SIDU_RS10320
uniprot id: A0A1L5BPQ6
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS14290
gene id: 861109:SIDU_RS14290
uniprot id: A0A1L5BRX2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

861109:SIDU RS12080
gene id: 861109:SIDU_RS12080
uniprot id: A0A1L5BQU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS15970
gene id: 861109:SIDU_RS15970
uniprot id: A0A1L5BSI2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

861109:SIDU RS13490
gene id: 861109:SIDU_RS13490
uniprot id: I5BAA6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

861109:SIDU RS00235
gene id: 861109:SIDU_RS00235
uniprot id: A0A1L5BJM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

861109:SIDU RS15445
gene id: 861109:SIDU_RS15445
uniprot id: A0A1L5BSG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

861109:SIDU RS11450
gene id: 861109:SIDU_RS11450
uniprot id: A0A1L5BQ87
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

861109:SIDU RS16055
gene id: 861109:SIDU_RS16055
uniprot id: A0A1L5BSJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

861109:SIDU RS04285
gene id: 861109:SIDU_RS04285
uniprot id: A0A1L5BLV9
names: Similarity
messages: Belongs to the peptidase A24 family.

861109:SIDU RS19000
gene id: 861109:SIDU_RS19000
uniprot id: A0A1L5BUZ7
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

861109:SIDU RS13405
gene id: 861109:SIDU_RS13405
uniprot id: A0A1L5BR65
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

861109:SIDU RS09900
gene id: 861109:SIDU_RS09900
uniprot id: A0A1L5BPP2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

861109:SIDU RS03200
gene id: 861109:SIDU_RS03200
uniprot id: A0A1L5BLA8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

861109:SIDU RS13505
gene id: 861109:SIDU_RS13505
uniprot id: A0A1L5BR97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

861109:SIDU RS18430
gene id: 861109:SIDU_RS18430
uniprot id: A0A1L5BUM0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS02635
gene id: 861109:SIDU_RS02635
uniprot id: A0A1L5BKU5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

861109:SIDU RS00960
gene id: 861109:SIDU_RS00960
uniprot id: A0A1L5BTI7
names: Similarity
messages: Belongs to the GcvT family.

861109:SIDU RS09765
gene id: 861109:SIDU_RS09765
uniprot id: A0A1L5BPF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS00835
gene id: 861109:SIDU_RS00835
uniprot id: A0A1L5BK66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

861109:SIDU RS02630
gene id: 861109:SIDU_RS02630
uniprot id: A0A1L5BL14
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

861109:SIDU RS11865
gene id: 861109:SIDU_RS11865
uniprot id: A0A1L5BQD0
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

861109:SIDU RS03415
gene id: 861109:SIDU_RS03415
uniprot id: A0A1L5BL35
names: Similarity
messages: Belongs to the SBNO family.

861109:SIDU RS14320
gene id: 861109:SIDU_RS14320
uniprot id: A0A1L5BRN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

861109:SIDU RS14875
gene id: 861109:SIDU_RS14875
uniprot id: A0A1L5BS35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

861109:SIDU RS16885
gene id: 861109:SIDU_RS16885
uniprot id: A0A1L5BSZ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS05340
gene id: 861109:SIDU_RS05340
uniprot id: I5BDT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS13940
gene id: 861109:SIDU_RS13940
uniprot id: A0A1L5BRS0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

861109:SIDU RS07390
gene id: 861109:SIDU_RS07390
uniprot id: A0A1L5BNG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

861109:SIDU RS02370
gene id: 861109:SIDU_RS02370
uniprot id: A0A1L5BKQ0
names: Similarity
messages: Belongs to the TlyA family.

861109:SIDU RS03335
gene id: 861109:SIDU_RS03335
uniprot id: A0A1L5BL69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

861109:SIDU RS06500
gene id: 861109:SIDU_RS06500
uniprot id: A0A1L5BMZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

861109:SIDU RS06625
gene id: 861109:SIDU_RS06625
uniprot id: A0A1L5BMQ5
names: Similarity
messages: Belongs to the ArsC family.

861109:SIDU RS06665
gene id: 861109:SIDU_RS06665
uniprot id: A0A1L5BMU0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

861109:SIDU RS16130
gene id: 861109:SIDU_RS16130
uniprot id: A0A1L5BSK3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

861109:SIDU RS03085
gene id: 861109:SIDU_RS03085
uniprot id: A0A1L5BL63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS07595
gene id: 861109:SIDU_RS07595
uniprot id: A0A1L5BN81
names: Similarity
messages: Belongs to the Gfa family.

861109:SIDU RS04525
gene id: 861109:SIDU_RS04525
uniprot id: A0A1L5BTQ0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

861109:SIDU RS02470
gene id: 861109:SIDU_RS02470
uniprot id: A0A1L5BKS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS02830
gene id: 861109:SIDU_RS02830
uniprot id: A0A1L5BL57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS05735
gene id: 861109:SIDU_RS05735
uniprot id: A0A1L5BM95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS13475
gene id: 861109:SIDU_RS13475
uniprot id: A0A1L5BRI9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

861109:SIDU RS05760
gene id: 861109:SIDU_RS05760
uniprot id: A0A1L5BME0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

861109:SIDU RS09515
gene id: 861109:SIDU_RS09515
uniprot id: A0A1L5BPA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

861109:SIDU RS15785
gene id: 861109:SIDU_RS15785
uniprot id: A0A1L5BSE0
names: Similarity
messages: Belongs to the UPF0260 family.

861109:SIDU RS04200
gene id: 861109:SIDU_RS04200
uniprot id: A0A1L5BLR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

861109:SIDU RS10735
gene id: 861109:SIDU_RS10735
uniprot id: A0A1L5BPW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

861109:SIDU RS16645
gene id: 861109:SIDU_RS16645
uniprot id: A0A1L5BSV7
names: Similarity
messages: Belongs to the cytochrome P450 family.

861109:SIDU RS18215
gene id: 861109:SIDU_RS18215
uniprot id: A0A1L5BQ97
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

861109:SIDU RS06615
gene id: 861109:SIDU_RS06615
uniprot id: A0A1L5BMT1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

861109:SIDU RS11970
gene id: 861109:SIDU_RS11970
uniprot id: A0A1L5BQF0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861109:SIDU RS18395
gene id: 861109:SIDU_RS18395
uniprot id: A0A1L5BUM3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

861109:SIDU RS09165
gene id: 861109:SIDU_RS09165
uniprot id: A0A1L5BP52
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

861109:SIDU RS17715
gene id: 861109:SIDU_RS17715
uniprot id: A0A1L5BUB8
names: Similarity
messages: Belongs to the ArsC family.

861109:SIDU RS11705
gene id: 861109:SIDU_RS11705
uniprot id: A0A1L5BQJ8
names: Similarity
messages: Belongs to the RelE toxin family.

861109:SIDU RS07535
gene id: 861109:SIDU_RS07535
uniprot id: A0A1L5BTU4
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS10255
gene id: 861109:SIDU_RS10255
uniprot id: A0A1L5BPP1
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS00395
gene id: 861109:SIDU_RS00395
uniprot id: A0A1L5BJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

861109:SIDU RS04930
gene id: 861109:SIDU_RS04930
uniprot id: I5BCJ6
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

861109:SIDU RS17520
gene id: 861109:SIDU_RS17520
uniprot id: A0A1L5BTA8
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS17305
gene id: 861109:SIDU_RS17305
uniprot id: A0A1L5BT80
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS01595
gene id: 861109:SIDU_RS01595
uniprot id: A0A1L5BKD6
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

861109:SIDU RS01430
gene id: 861109:SIDU_RS01430
uniprot id: A0A1L5BKF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

861109:SIDU RS03375
gene id: 861109:SIDU_RS03375
uniprot id: A0A1L5BTT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Membrane

861109:SIDU RS04770
gene id: 861109:SIDU_RS04770
uniprot id: A0A1L5BLS2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

861109:SIDU RS18705
gene id: 861109:SIDU_RS18705
uniprot id: A0A1L5BUU0
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

861109:SIDU RS15900
gene id: 861109:SIDU_RS15900
uniprot id: A0A1L5BSH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS16305
gene id: 861109:SIDU_RS16305
uniprot id: A0A1L5BSY5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

861109:SIDU RS06680
gene id: 861109:SIDU_RS06680
uniprot id: A0A1L5BN42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

861109:SIDU RS07715
gene id: 861109:SIDU_RS07715
uniprot id: A0A1L5BTU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

861109:SIDU RS11020
gene id: 861109:SIDU_RS11020
uniprot id: A0A1L5BQ16
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

861109:SIDU RS17220
gene id: 861109:SIDU_RS17220
uniprot id: A0A1L5BT64
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS01365
gene id: 861109:SIDU_RS01365
uniprot id: A0A1L5BTH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

861109:SIDU RS04300
gene id: 861109:SIDU_RS04300
uniprot id: A0A1L5BTV7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

861109:SIDU RS03015
gene id: 861109:SIDU_RS03015
uniprot id: I5BBR7
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

861109:SIDU RS14925
gene id: 861109:SIDU_RS14925
uniprot id: A0A1L5BS49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

861109:SIDU RS04655
gene id: 861109:SIDU_RS04655
uniprot id: A0A1L5BLY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS16165
gene id: 861109:SIDU_RS16165
uniprot id: A0A1L5BSL7
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

861109:SIDU RS07935
gene id: 861109:SIDU_RS07935
uniprot id: A0A1L5BNI4
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

861109:SIDU RS10805
gene id: 861109:SIDU_RS10805
uniprot id: A0A1L5BPY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

861109:SIDU RS04455
gene id: 861109:SIDU_RS04455
uniprot id: I5BCK6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

861109:SIDU RS05590
gene id: 861109:SIDU_RS05590
uniprot id: A0A1L5BMK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

861109:SIDU RS04050
gene id: 861109:SIDU_RS04050
uniprot id: A0A1L5BLJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

861109:SIDU RS03230
gene id: 861109:SIDU_RS03230
uniprot id: A0A1L5BL47
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS07495
gene id: 861109:SIDU_RS07495
uniprot id: A0A1L5BNH6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

861109:SIDU RS07665
gene id: 861109:SIDU_RS07665
uniprot id: I5BHM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

861109:SIDU RS03345
gene id: 861109:SIDU_RS03345
uniprot id: A0A1L5BL28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

861109:SIDU RS13040
gene id: 861109:SIDU_RS13040
uniprot id: A0A1L5BR31
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS06765
gene id: 861109:SIDU_RS06765
uniprot id: A0A1L5BN53
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861109:SIDU RS18365
gene id: 861109:SIDU_RS18365
uniprot id: A0A1L5BUL5
names: Similarity
messages: Belongs to the ParB family.

861109:SIDU RS01415
gene id: 861109:SIDU_RS01415
uniprot id: A0A1L5BK62
names: Similarity
messages: Belongs to the GSP E family.

861109:SIDU RS15870
gene id: 861109:SIDU_RS15870
uniprot id: A0A1L5BSF3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS03050
gene id: 861109:SIDU_RS03050
uniprot id: A0A1L5BTM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

861109:SIDU RS05660
gene id: 861109:SIDU_RS05660
uniprot id: A0A1L5BMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

861109:SIDU RS11035
gene id: 861109:SIDU_RS11035
uniprot id: A0A1L5BTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

861109:SIDU RS10795
gene id: 861109:SIDU_RS10795
uniprot id: A0A1L5BPV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

861109:SIDU RS08220
gene id: 861109:SIDU_RS08220
uniprot id: A0A1L5BNS7
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

861109:SIDU RS10245
gene id: 861109:SIDU_RS10245
uniprot id: A0A1L5BPJ3
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

861109:SIDU RS16190
gene id: 861109:SIDU_RS16190
uniprot id: A0A1L5BSL2
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS05070
gene id: 861109:SIDU_RS05070
uniprot id: A0A1L5BM20
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

861109:SIDU RS01015
gene id: 861109:SIDU_RS01015
uniprot id: A0A1L5BKA5
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

861109:SIDU RS16595
gene id: 861109:SIDU_RS16595
uniprot id: A0A1L5BSU8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

861109:SIDU RS17930
gene id: 861109:SIDU_RS17930
uniprot id: A0A1L5BUF7
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS10045
gene id: 861109:SIDU_RS10045
uniprot id: A0A1L5BPF8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

861109:SIDU RS03665
gene id: 861109:SIDU_RS03665
uniprot id: A0A1L5BLG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

861109:SIDU RS15310
gene id: 861109:SIDU_RS15310
uniprot id: A0A1L5BSB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS18750
gene id: 861109:SIDU_RS18750
uniprot id: A0A1L5BUT9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

861109:SIDU RS13845
gene id: 861109:SIDU_RS13845
uniprot id: A0A1L5BRE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

861109:SIDU RS05100
gene id: 861109:SIDU_RS05100
uniprot id: A0A1L5BTP8
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS17490
gene id: 861109:SIDU_RS17490
uniprot id: A0A1L5BTD9
names: Function
messages: Acts on leucine, isoleucine and valine.

861109:SIDU RS02605
gene id: 861109:SIDU_RS02605
uniprot id: A0A1L5BL22
names: Function
messages: Multidrug efflux pump.

861109:SIDU RS05195
gene id: 861109:SIDU_RS05195
uniprot id: A0A1L5BM70
names: Similarity
messages: Belongs to the PhoH family.

861109:SIDU RS17835
gene id: 861109:SIDU_RS17835
uniprot id: A0A1L5BUB6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS13675
gene id: 861109:SIDU_RS13675
uniprot id: A0A1L5BU36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

861109:SIDU RS01275
gene id: 861109:SIDU_RS01275
uniprot id: A0A1L5BKF9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

861109:SIDU RS10610
gene id: 861109:SIDU_RS10610
uniprot id: A0A1L5BQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

861109:SIDU RS02740
gene id: 861109:SIDU_RS02740
uniprot id: A0A1L5BKW8
names: Similarity
messages: Belongs to the AHA1 family.

861109:SIDU RS04010
gene id: 861109:SIDU_RS04010
uniprot id: A0A1L5BLE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

861109:SIDU RS03030
gene id: 861109:SIDU_RS03030
uniprot id: I5BBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

861109:SIDU RS05820
gene id: 861109:SIDU_RS05820
uniprot id: A0A1L5BMH4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

861109:SIDU RS18385
gene id: 861109:SIDU_RS18385
uniprot id: A0A1L5BUM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

861109:SIDU RS04045
gene id: 861109:SIDU_RS04045
uniprot id: A0A1L5BLR9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

861109:SIDU RS05135
gene id: 861109:SIDU_RS05135
uniprot id: A0A1L5BLY2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

861109:SIDU RS10230
gene id: 861109:SIDU_RS10230
uniprot id: A0A1L5BPV2
names: Similarity
messages: Belongs to the type IB topoisomerase family.

861109:SIDU RS18460
gene id: 861109:SIDU_RS18460
uniprot id: A0A1L5BUQ5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

861109:SIDU RS04790
gene id: 861109:SIDU_RS04790
uniprot id: A0A1L5BLV4
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

861109:SIDU RS04130
gene id: 861109:SIDU_RS04130
uniprot id: A0A1L5BLF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS01455
gene id: 861109:SIDU_RS01455
uniprot id: A0A1L5BTH8
names: Cofactor
messages: Binds 1 zinc ion per subunit.

861109:SIDU RS13165
gene id: 861109:SIDU_RS13165
uniprot id: A0A1L5BR42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS12285
gene id: 861109:SIDU_RS12285
uniprot id: A0A1L5BQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

861109:SIDU RS06740
gene id: 861109:SIDU_RS06740
uniprot id: A0A1L5BMT4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

861109:SIDU RS04160
gene id: 861109:SIDU_RS04160
uniprot id: A0A1L5BLF9
names: Similarity
messages: Belongs to the UPF0758 family.

861109:SIDU RS04715
gene id: 861109:SIDU_RS04715
uniprot id: A0A1L5BLZ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

861109:SIDU RS05705
gene id: 861109:SIDU_RS05705
uniprot id: A0A1L5BTP7
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

861109:SIDU RS11250
gene id: 861109:SIDU_RS11250
uniprot id: A0A1L5BQ64
names: Function
names: Subcellular Location Annotation
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane

861109:SIDU RS07010
gene id: 861109:SIDU_RS07010
uniprot id: A0A1L5BMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

861109:SIDU RS09065
gene id: 861109:SIDU_RS09065
uniprot id: A0A1L5BNZ2
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS16415
gene id: 861109:SIDU_RS16415
uniprot id: A0A1L5BUA9
names: Similarity
messages: Belongs to the GARS family.

861109:SIDU RS12980
gene id: 861109:SIDU_RS12980
uniprot id: A0A1L5BR18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

861109:SIDU RS16045
gene id: 861109:SIDU_RS16045
uniprot id: A0A1L5BU96
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

861109:SIDU RS16880
gene id: 861109:SIDU_RS16880
uniprot id: A0A1L5BT04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

861109:SIDU RS03035
gene id: 861109:SIDU_RS03035
uniprot id: I5BFX5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS14960
gene id: 861109:SIDU_RS14960
uniprot id: A0A1L5BRY8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

861109:SIDU RS04560
gene id: 861109:SIDU_RS04560
uniprot id: A0A1L5BM07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

861109:SIDU RS12800
gene id: 861109:SIDU_RS12800
uniprot id: A0A1L5BQY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

861109:SIDU RS18625
gene id: 861109:SIDU_RS18625
uniprot id: A0A1L5BUQ2
names: Similarity
messages: Belongs to the autoinducer synthase family.

861109:SIDU RS18660
gene id: 861109:SIDU_RS18660
uniprot id: A0A1L5BUR8
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 copper ion per subunit.
messages: Periplasm

861109:SIDU RS02270
gene id: 861109:SIDU_RS02270
uniprot id: A0A1L5BKT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

861109:SIDU RS12770
gene id: 861109:SIDU_RS12770
uniprot id: A0A1L5BQU7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

861109:SIDU RS12345
gene id: 861109:SIDU_RS12345
uniprot id: A0A1L5BQL2
names: Similarity
messages: Belongs to the autoinducer synthase family.

861109:SIDU RS04610
gene id: 861109:SIDU_RS04610
uniprot id: A0A1L5BLS3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

861109:SIDU RS02170
gene id: 861109:SIDU_RS02170
uniprot id: A0A1L5BKL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

861109:SIDU RS02460
gene id: 861109:SIDU_RS02460
uniprot id: A0A1L5BKL9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is located at the dimer interface.

861109:SIDU RS02930
gene id: 861109:SIDU_RS02930
uniprot id: A0A1L5BTJ9
names: Similarity
messages: Belongs to the thioesterase PaaI family.

861109:SIDU RS17665
gene id: 861109:SIDU_RS17665
uniprot id: A0A1L5BTF8
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

861109:SIDU RS04605
gene id: 861109:SIDU_RS04605
uniprot id: A0A1L5BLY0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

861109:SIDU RS12850
gene id: 861109:SIDU_RS12850
uniprot id: A0A1L5BQZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

861109:SIDU RS02755
gene id: 861109:SIDU_RS02755
uniprot id: A0A1L5BKS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

861109:SIDU RS12410
gene id: 861109:SIDU_RS12410
uniprot id: A0A1L5BQR9
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS14770
gene id: 861109:SIDU_RS14770
uniprot id: A0A1L5BS46
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

861109:SIDU RS13735
gene id: 861109:SIDU_RS13735
uniprot id: A0A1L5BRD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

861109:SIDU RS04395
gene id: 861109:SIDU_RS04395
uniprot id: A0A1L5BLP9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

861109:SIDU RS12695
gene id: 861109:SIDU_RS12695
uniprot id: A0A1L5BQW6
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

861109:SIDU RS04500
gene id: 861109:SIDU_RS04500
uniprot id: A0A1L5BLZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

861109:SIDU RS06560
gene id: 861109:SIDU_RS06560
uniprot id: A0A1L5BMK6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

861109:SIDU RS10525
gene id: 861109:SIDU_RS10525
uniprot id: A0A1L5BPP9
names: Similarity
messages: Belongs to the YggT family.

861109:SIDU RS07490
gene id: 861109:SIDU_RS07490
uniprot id: A0A1L5BNA4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

861109:SIDU RS04260
gene id: 861109:SIDU_RS04260
uniprot id: A0A1L5BLS6
names: Similarity
messages: Belongs to the GSP E family.

861109:SIDU RS12805
gene id: 861109:SIDU_RS12805
uniprot id: A0A1L5BR70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

861109:SIDU RS08225
gene id: 861109:SIDU_RS08225
uniprot id: A0A1L5BNK6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS09760
gene id: 861109:SIDU_RS09760
uniprot id: A0A1L5BTX6
names: Similarity
messages: Belongs to the citrate synthase family.

861109:SIDU RS10865
gene id: 861109:SIDU_RS10865
uniprot id: A0A1L5BQA0
names: Similarity
messages: Belongs to the IlvD/Edd family.

861109:SIDU RS07145
gene id: 861109:SIDU_RS07145
uniprot id: A0A1L5BMZ1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

861109:SIDU RS07895
gene id: 861109:SIDU_RS07895
uniprot id: I5BEZ4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

861109:SIDU RS10305
gene id: 861109:SIDU_RS10305
uniprot id: A0A1L5BPQ0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

861109:SIDU RS16125
gene id: 861109:SIDU_RS16125
uniprot id: A0A1L5BSM8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS09020
gene id: 861109:SIDU_RS09020
uniprot id: A0A1L5BPA6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

861109:SIDU RS14995
gene id: 861109:SIDU_RS14995
uniprot id: A0A1L5BS03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

861109:SIDU RS18290
gene id: 861109:SIDU_RS18290
uniprot id: A0A1L5BUJ0
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

861109:SIDU RS00365
gene id: 861109:SIDU_RS00365
uniprot id: A0A1L5BJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

861109:SIDU RS07830
gene id: 861109:SIDU_RS07830
uniprot id: A0A1L5BNG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

861109:SIDU RS10310
gene id: 861109:SIDU_RS10310
uniprot id: A0A1L5BPK5
names: Similarity
messages: Belongs to the FBPase class 2 family.

861109:SIDU RS10575
gene id: 861109:SIDU_RS10575
uniprot id: A0A1L5BPQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

861109:SIDU RS06715
gene id: 861109:SIDU_RS06715
uniprot id: A0A1L5BMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

861109:SIDU RS16155
gene id: 861109:SIDU_RS16155
uniprot id: A0A1L5BSL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

861109:SIDU RS10470
gene id: 861109:SIDU_RS10470
uniprot id: A0A1L5BTZ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

861109:SIDU RS03040
gene id: 861109:SIDU_RS03040
uniprot id: I5BFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

861109:SIDU RS04075
gene id: 861109:SIDU_RS04075
uniprot id: A0A1L5BLN8
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

861109:SIDU RS08005
gene id: 861109:SIDU_RS08005
uniprot id: A0A1L5BNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

861109:SIDU RS14570
gene id: 861109:SIDU_RS14570
uniprot id: A0A1L5BS09
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

861109:SIDU RS02465
gene id: 861109:SIDU_RS02465
uniprot id: A0A1L5BL02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS04800
gene id: 861109:SIDU_RS04800
uniprot id: A0A1L5BLR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

861109:SIDU RS07835
gene id: 861109:SIDU_RS07835
uniprot id: A0A1L5BNN8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

861109:SIDU RS04630
gene id: 861109:SIDU_RS04630
uniprot id: A0A1L5BM17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

861109:SIDU RS06590
gene id: 861109:SIDU_RS06590
uniprot id: A0A1L5BMQ8
names: Similarity
messages: Belongs to the CmpA/NrtA family.

861109:SIDU RS07455
gene id: 861109:SIDU_RS07455
uniprot id: A0A1L5BN76
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS00930
gene id: 861109:SIDU_RS00930
uniprot id: A0A1L5BK54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

861109:SIDU RS18210
gene id: 861109:SIDU_RS18210
uniprot id: A0A1L5BUH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS06995
gene id: 861109:SIDU_RS06995
uniprot id: A0A1L5BMZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

861109:SIDU RS16695
gene id: 861109:SIDU_RS16695
uniprot id: A0A1L5BSX2
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

861109:SIDU RS06755
gene id: 861109:SIDU_RS06755
uniprot id: A0A1L5BTV2
names: Similarity
messages: Belongs to the fabD family.

861109:SIDU RS08935
gene id: 861109:SIDU_RS08935
uniprot id: A0A1L5BNT5
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS09365
gene id: 861109:SIDU_RS09365
uniprot id: A0A1L5BP40
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

861109:SIDU RS07575
gene id: 861109:SIDU_RS07575
uniprot id: A0A1L5BN64
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

861109:SIDU RS01420
gene id: 861109:SIDU_RS01420
uniprot id: A0A1L5BKB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

861109:SIDU RS12380
gene id: 861109:SIDU_RS12380
uniprot id: A0A1L5BQM5
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

861109:SIDU RS04780
gene id: 861109:SIDU_RS04780
uniprot id: A0A1L5BM46
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS13550
gene id: 861109:SIDU_RS13550
uniprot id: A0A1L5BR91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

861109:SIDU RS10130
gene id: 861109:SIDU_RS10130
uniprot id: A0A1L5BPL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

861109:SIDU RS01900
gene id: 861109:SIDU_RS01900
uniprot id: A0A1L5BKD5
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.

861109:SIDU RS05800
gene id: 861109:SIDU_RS05800
uniprot id: A0A1L5BMB6
names: Similarity
messages: Belongs to the virb1 family.

861109:SIDU RS11215
gene id: 861109:SIDU_RS11215
uniprot id: A0A1L5BQ09
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

861109:SIDU RS06410
gene id: 861109:SIDU_RS06410
uniprot id: A0A1L5BMZ7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

861109:SIDU RS16865
gene id: 861109:SIDU_RS16865
uniprot id: A0A1L5BT16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS16440
gene id: 861109:SIDU_RS16440
uniprot id: A0A1L5BSQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

861109:SIDU RS07825
gene id: 861109:SIDU_RS07825
uniprot id: A0A1L5BNC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

861109:SIDU RS18165
gene id: 861109:SIDU_RS18165
uniprot id: A0A1L5BUJ8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS18985
gene id: 861109:SIDU_RS18985
uniprot id: A0A1L5BUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

861109:SIDU RS10695
gene id: 861109:SIDU_RS10695
uniprot id: A0A1L5BTY6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS02965
gene id: 861109:SIDU_RS02965
uniprot id: A0A1L5BKZ6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

861109:SIDU RS06710
gene id: 861109:SIDU_RS06710
uniprot id: A0A1L5BMU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

861109:SIDU RS00735
gene id: 861109:SIDU_RS00735
uniprot id: A0A1L5BJU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

861109:SIDU RS18845
gene id: 861109:SIDU_RS18845
uniprot id: A0A1L5BUV4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

861109:SIDU RS06830
gene id: 861109:SIDU_RS06830
uniprot id: A0A1L5BMX0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

861109:SIDU RS04665
gene id: 861109:SIDU_RS04665
uniprot id: A0A1L5BLZ0
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS09305
gene id: 861109:SIDU_RS09305
uniprot id: A0A1L5BP11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

861109:SIDU RS15740
gene id: 861109:SIDU_RS15740
uniprot id: A0A1L5BSC8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

861109:SIDU RS11915
gene id: 861109:SIDU_RS11915
uniprot id: A0A1L5BQD7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

861109:SIDU RS16160
gene id: 861109:SIDU_RS16160
uniprot id: A0A1L5BSK8
names: Similarity
messages: Belongs to the YkuD family.

861109:SIDU RS06750
gene id: 861109:SIDU_RS06750
uniprot id: A0A1L5BTR3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

861109:SIDU RS07750
gene id: 861109:SIDU_RS07750
uniprot id: A0A1L5BN69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

861109:SIDU RS00285
gene id: 861109:SIDU_RS00285
uniprot id: A0A1L5BTG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

861109:SIDU RS13950
gene id: 861109:SIDU_RS13950
uniprot id: A0A1L5BRJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS17470
gene id: 861109:SIDU_RS17470
uniprot id: A0A1L5BTD0
names: Similarity
messages: Belongs to the peptidase U62 family.

861109:SIDU RS04310
gene id: 861109:SIDU_RS04310
uniprot id: A0A1L5BLS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

861109:SIDU RS15400
gene id: 861109:SIDU_RS15400
uniprot id: A0A1L5BS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

861109:SIDU RS06645
gene id: 861109:SIDU_RS06645
uniprot id: A0A1L5BMR6
names: Subcellular Location Annotation
messages: Membrane

861109:SIDU RS04425
gene id: 861109:SIDU_RS04425
uniprot id: I5B8Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

861109:SIDU RS14850
gene id: 861109:SIDU_RS14850
uniprot id: A0A1L5BRX3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

861109:SIDU RS09990
gene id: 861109:SIDU_RS09990
uniprot id: A0A1L5BPF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.