8478:NR3C1
gene id: 8478:NR3C1
uniprot id: A0A8C3HUI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

8478:CAMK2G
gene id: 8478:CAMK2G
uniprot id: A0A8C3I6N2
uniprot id: A0A8C3I7H0
uniprot id: A0A8C3I8U1
uniprot id: A0A8C3PB13
uniprot id: A0A8C3PB15
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8478:UTP14A
gene id: 8478:UTP14A
uniprot id: A0A8C3P328
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

8478:TMEM45A
gene id: 8478:TMEM45A
uniprot id: A0A8C3H6V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

8478:SOSTDC1
gene id: 8478:SOSTDC1
uniprot id: A0A8C3IAY5
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:MLLT3
gene id: 8478:MLLT3
uniprot id: A0A8C3I171
names: Subcellular Location Annotation
messages: Nucleus

8478:SLC33A1
gene id: 8478:SLC33A1
uniprot id: A0A8C3HZM3
names: Subcellular Location Annotation
messages: Membrane

8478:CENPL
gene id: 8478:CENPL
uniprot id: A0A8C3HNH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

8478:E2F6
gene id: 8478:E2F6
uniprot id: A0A8C3HK03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8478:POLR1E
gene id: 8478:POLR1E
uniprot id: A0A8C3FPK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

8478:FNIP1
gene id: 8478:FNIP1
uniprot id: A0A8C3IM75
uniprot id: A0A8C3IN25
uniprot id: A0A8C3PE78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

8478:MUL1
gene id: 8478:MUL1
uniprot id: A0A8C3IKF3
names: Subcellular Location Annotation
messages: Membrane

8478:SH3BGRL2
gene id: 8478:SH3BGRL2
uniprot id: A0A8C3IEZ3
names: Similarity
messages: Belongs to the SH3BGR family.

8478:FGF23
gene id: 8478:FGF23
uniprot id: A0A8C3HAS3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8478:CCM2
gene id: 8478:CCM2
uniprot id: A0A8C3HPT5
names: Similarity
messages: Belongs to the CCM2 family.

8478:LEO1
gene id: 8478:LEO1
uniprot id: A0A8C3IX57
names: Similarity
messages: Belongs to the LEO1 family.

8478:HBS1L
gene id: 8478:HBS1L
uniprot id: A0A8C3HXA3
names: Subcellular Location Annotation
messages: Cytoplasm

8478:LOC101932249
gene id: 8478:LOC101932249
uniprot id: A0A8C3I5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8478:SUSD6
gene id: 8478:SUSD6
uniprot id: A0A8C3IAU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:BCL7A
gene id: 8478:BCL7A
uniprot id: A0A8C3IT67
names: Similarity
messages: Belongs to the BCL7 family.

8478:CER1
gene id: 8478:CER1
uniprot id: A0A8C3INV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8478:GORAB
gene id: 8478:GORAB
uniprot id: A0A8C3HGI8
names: Similarity
messages: Belongs to the GORAB family.

8478:SNX19
gene id: 8478:SNX19
uniprot id: A0A8C3PFD1
names: Similarity
messages: Belongs to the sorting nexin family.

8478:NDUFAF7
gene id: 8478:NDUFAF7
uniprot id: A0A8C3IJK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

8478:GABRA4
gene id: 8478:GABRA4
uniprot id: A0A8C3IZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8478:PTX3
gene id: 8478:PTX3
uniprot id: A0A8C3HZ60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:RPL14
gene id: 8478:RPL14
uniprot id: A0A8C3IER9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

8478:STARD8
gene id: 8478:STARD8
uniprot id: A0A8C3FI71
names: Subcellular Location Annotation
messages: Cytoplasm

8478:LSM3
gene id: 8478:LSM3
uniprot id: A0A8C3HM79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

8478:LZIC
gene id: 8478:LZIC
uniprot id: A0A8C3IBN6
names: Similarity
messages: Belongs to the CTNNBIP1 family.

8478:DBNDD1
gene id: 8478:DBNDD1
uniprot id: A0A8C3HJ88
names: Similarity
messages: Belongs to the dysbindin family.

8478:CPEB4
gene id: 8478:CPEB4
uniprot id: A0A8C3FJL2
uniprot id: A0A8C3FJW2
names: Similarity
messages: Belongs to the RRM CPEB family.

8478:CMPK2
gene id: 8478:CMPK2
uniprot id: A0A8C3HKH2
names: Similarity
messages: Belongs to the thymidylate kinase family.

8478:ACVR2B
gene id: 8478:ACVR2B
uniprot id: A0A8C3P9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8478:VPS18
gene id: 8478:VPS18
uniprot id: A0A8C3HID8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

8478:GANAB
gene id: 8478:GANAB
uniprot id: A0A8C3HY79
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8478:HCRTR2
gene id: 8478:HCRTR2
uniprot id: A0A8C3IE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:SLC29A4
gene id: 8478:SLC29A4
uniprot id: A0A8C3PB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

8478:ERO1B
gene id: 8478:ERO1B
uniprot id: A0A8C3F998
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

8478:ENPP3
gene id: 8478:ENPP3
uniprot id: A0A8C3HYI4
names: Subcellular Location Annotation
messages: Secreted

8478:SPDYC
gene id: 8478:SPDYC
uniprot id: A0A8C3PD37
names: Similarity
messages: Belongs to the Speedy/Ringo family.

8478:ACTN1
gene id: 8478:ACTN1
uniprot id: A0A8C3I9R3
uniprot id: A0A8C3IAI1
uniprot id: A0A8C3IAJ5
names: Similarity
messages: Belongs to the alpha-actinin family.

8478:SLX4
gene id: 8478:SLX4
uniprot id: A0A8C3ISD3
names: Similarity
messages: Belongs to the SLX4 family.

8478:SLCO1A2
gene id: 8478:SLCO1A2
uniprot id: A0A8C3FWD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8478:RPS6
gene id: 8478:RPS6
uniprot id: A0A8C3P9W1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

8478:SERP1
gene id: 8478:SERP1
uniprot id: A0A8C3HLV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

8478:GREB1
gene id: 8478:GREB1
uniprot id: A0A8C3HKB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

8478:EMC8
gene id: 8478:EMC8
uniprot id: A0A8C3IHJ0
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

8478:LOC101939668
gene id: 8478:LOC101939668
uniprot id: A0A8C3FZR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8478:PEX3
gene id: 8478:PEX3
uniprot id: A0A8C3HVR9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

8478:LOC101942618
gene id: 8478:LOC101942618
uniprot id: A0A8C3I568
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

8478:STMN2
gene id: 8478:STMN2
uniprot id: A0A8C3FHX7
names: Similarity
messages: Belongs to the stathmin family.

8478:FSCN1
gene id: 8478:FSCN1
uniprot id: A0A8C3I9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8478:LOC101944980
gene id: 8478:LOC101944980
uniprot id: A0A8C3I7U5
uniprot id: A0A8C3I9A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

8478:DACT1
gene id: 8478:DACT1
uniprot id: A0A8C3PE07
names: Similarity
messages: Belongs to the dapper family.

8478:VPS51
gene id: 8478:VPS51
uniprot id: A0A8C3IG76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Endosome
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

8478:GAB3
gene id: 8478:GAB3
uniprot id: A0A8C3F1E8
names: Similarity
messages: Belongs to the GAB family.

8478:TCIRG1
gene id: 8478:TCIRG1
uniprot id: A0A8C3P8H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8478:GDF7
gene id: 8478:GDF7
uniprot id: A0A8C3I4J1
names: Similarity
messages: Belongs to the TGF-beta family.

8478:EMC1
gene id: 8478:EMC1
uniprot id: A0A8C3IJ31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:IL10
gene id: 8478:IL10
uniprot id: A0A8C3H5R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

8478:SNX32
gene id: 8478:SNX32
uniprot id: A0A8C3IGA5
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

8478:MRTO4
gene id: 8478:MRTO4
uniprot id: A0A8C3IHI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

8478:RMND1
gene id: 8478:RMND1
uniprot id: A0A8C3P890
names: Similarity
messages: Belongs to the RMD1/sif2 family.

8478:BSX
gene id: 8478:BSX
uniprot id: A0A8C3HNU5
names: Subcellular Location Annotation
messages: Nucleus

8478:EAF1
gene id: 8478:EAF1
uniprot id: A0A8C3PCI1
names: Similarity
messages: Belongs to the EAF family.

8478:NDUFB3
gene id: 8478:NDUFB3
uniprot id: A0A8C3HCC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

8478:ETV5
gene id: 8478:ETV5
uniprot id: A0A8C3FIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8478:LOC101950931
gene id: 8478:LOC101950931
uniprot id: A0A8C3HBG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8478:STX17
gene id: 8478:STX17
uniprot id: A0A8C3H5J0
names: Similarity
messages: Belongs to the syntaxin family.

8478:LOC101950830
gene id: 8478:LOC101950830
uniprot id: A0A8C3FSU2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8478:TMEFF1
gene id: 8478:TMEFF1
uniprot id: A0A8C3F5T4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:TADA1
gene id: 8478:TADA1
uniprot id: A0A8C3F7C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

8478:TLN2
gene id: 8478:TLN2
uniprot id: A0A8C3HXH8
names: Subcellular Location Annotation
messages: cytoskeleton

8478:UBIAD1
gene id: 8478:UBIAD1
uniprot id: A0A8C3PBZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

8478:RNF111
gene id: 8478:RNF111
uniprot id: A0A8C3FXH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arkadia family.
messages: PML body

8478:C2H5orf22
gene id: 8478:C2H5orf22
uniprot id: A0A8C3H503
names: Similarity
messages: Belongs to the UPF0489 family.

8478:TSPAN12
gene id: 8478:TSPAN12
uniprot id: A0A8C3FPV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:SEPTIN6
gene id: 8478:SEPTIN6
uniprot id: A0A8C3IA11
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8478:CCNT2
gene id: 8478:CCNT2
uniprot id: A0A8C3FSU9
uniprot id: A0A8C3HB57
names: Similarity
messages: Belongs to the cyclin family.

8478:LOC101946689
gene id: 8478:LOC101946689
uniprot id: A0A8C3I1F7
uniprot id: A0A8C3P9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8478:P2RY4
gene id: 8478:P2RY4
uniprot id: A0A8C3P6U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:FZD10
gene id: 8478:FZD10
uniprot id: A0A8C3ILG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8478:UBE3D
gene id: 8478:UBE3D
uniprot id: A0A8C3IIF3
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

8478:HIBADH
gene id: 8478:HIBADH
uniprot id: A0A8C3IDU8
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8478:SCN1B
gene id: 8478:SCN1B
uniprot id: A0A8C3FKT1
names: Subcellular Location Annotation
messages: Membrane

8478:LOC101938578
gene id: 8478:LOC101938578
uniprot id: A0A8C3FIS0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8478:IL18R1
gene id: 8478:IL18R1
uniprot id: A0A8C3H8U1
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8478:RAB11FIP3
gene id: 8478:RAB11FIP3
uniprot id: A0A8C3ILE3
uniprot id: A0A8C3PE18
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

8478:PKM
gene id: 8478:PKM
uniprot id: A0A8C3FGN8
names: Similarity
messages: Belongs to the pyruvate kinase family.

8478:DGKG
gene id: 8478:DGKG
uniprot id: A0A8C3FNJ7
uniprot id: A0A8C3H985
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8478:SLC25A25
gene id: 8478:SLC25A25
uniprot id: A0A8C3IMM5
uniprot id: A0A8C3IMT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8478:FAM120A
gene id: 8478:FAM120A
uniprot id: A0A8C3I3Q0
uniprot id: A0A8C3I6J8
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

8478:ST8SIA3
gene id: 8478:ST8SIA3
uniprot id: A0A8C3ISJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8478:RBM22
gene id: 8478:RBM22
uniprot id: A0A8C3FU74
uniprot id: A0A8C3HAL5
names: Similarity
messages: Belongs to the SLT11 family.

8478:LOC101940098
gene id: 8478:LOC101940098
uniprot id: A0A8C3FRV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8478:LOC101953600
gene id: 8478:LOC101953600
uniprot id: A0A8C3HQW0
names: Similarity
messages: Belongs to the SELO family.

8478:KIF25
gene id: 8478:KIF25
uniprot id: A0A8C3HER2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8478:LOC101939802
gene id: 8478:LOC101939802
uniprot id: A0A8C3HDP6
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8478:EXOG
gene id: 8478:EXOG
uniprot id: A0A8C3HYW6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

8478:ZDHHC24
gene id: 8478:ZDHHC24
uniprot id: A0A8C3PD90
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:SLC19A2
gene id: 8478:SLC19A2
uniprot id: A0A8C3F9B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Cell membrane
messages: High-affinity transporter for the intake of thiamine.

8478:LOC101948784
gene id: 8478:LOC101948784
uniprot id: A0A8C3FE16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

8478:LOC101933582
gene id: 8478:LOC101933582
uniprot id: A0A8C3I9D4
uniprot id: A0A8C3IBJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

8478:NUS1
gene id: 8478:NUS1
uniprot id: A0A8C3I242
names: Similarity
messages: Belongs to the UPP synthase family.

8478:LOC101953301
gene id: 8478:LOC101953301
uniprot id: A0A8C3I430
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8478:ADRA1B
gene id: 8478:ADRA1B
uniprot id: A0A8C3FKD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

8478:LOC101933933
gene id: 8478:LOC101933933
uniprot id: A0A8C3ITQ8
names: Subcellular Location Annotation
messages: Membrane

8478:LOC101951632
gene id: 8478:LOC101951632
uniprot id: A0A8C3IIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:VAMP4
gene id: 8478:VAMP4
uniprot id: A0A8C3HRI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8478:SNAP47
gene id: 8478:SNAP47
uniprot id: A0A8C3F478
names: Similarity
messages: Belongs to the SVAP1 family.

8478:NFE2L3
gene id: 8478:NFE2L3
uniprot id: A0A8C3IF99
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8478:EDA
gene id: 8478:EDA
uniprot id: A0A8C3HLU1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8478:HMGCLL1
gene id: 8478:HMGCLL1
uniprot id: A0A8C3ICG2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

8478:STOM
gene id: 8478:STOM
uniprot id: A0A8C3FRQ9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8478:MAP1LC3C
gene id: 8478:MAP1LC3C
uniprot id: A0A8C3FMX4
names: Similarity
messages: Belongs to the ATG8 family.

8478:NETO2
gene id: 8478:NETO2
uniprot id: A0A8C3HRR1
uniprot id: A0A8C3HSK0
uniprot id: A0A8C3P7Z2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:MMGT1
gene id: 8478:MMGT1
uniprot id: A0A8C3IQD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

8478:RPGRIP1L
gene id: 8478:RPGRIP1L
uniprot id: A0A8C3HDV3
names: Similarity
messages: Belongs to the RPGRIP1 family.

8478:LOC101952859
gene id: 8478:LOC101952859
uniprot id: A0A8C3HRK3
names: Similarity
messages: Belongs to the AKAP110 family.

8478:IL4R
gene id: 8478:IL4R
uniprot id: A0A8C3F837
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

8478:CPT2
gene id: 8478:CPT2
uniprot id: A0A8C3H4X3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8478:PDIA4
gene id: 8478:PDIA4
uniprot id: A0A8C3HUH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8478:SEMA3F
gene id: 8478:SEMA3F
uniprot id: A0A8C3F5K3
uniprot id: A0A8C3H6J8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:SSR3
gene id: 8478:SSR3
uniprot id: A0A8C3P9I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

8478:DMRT2
gene id: 8478:DMRT2
uniprot id: A0A8C3IP57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8478:MTFR2
gene id: 8478:MTFR2
uniprot id: A0A8C3HX61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

8478:LIN9
gene id: 8478:LIN9
uniprot id: A0A8C3HD12
uniprot id: A0A8C3HD15
names: Similarity
messages: Belongs to the lin-9 family.

8478:TMX2
gene id: 8478:TMX2
uniprot id: A0A8C3HUU8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

8478:DYNLT5
gene id: 8478:DYNLT5
uniprot id: A0A8C3F1F5
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8478:CAMK1G
gene id: 8478:CAMK1G
uniprot id: A0A8C3PBH4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:TBXAS1
gene id: 8478:TBXAS1
uniprot id: A0A8C3HHW6
names: Similarity
messages: Belongs to the cytochrome P450 family.

8478:FEZ2
gene id: 8478:FEZ2
uniprot id: A0A8C3IHC3
uniprot id: A0A8C3IJN0
names: Similarity
messages: Belongs to the zygin family.

8478:CSRNP2
gene id: 8478:CSRNP2
uniprot id: A0A8C3HYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8478:MYF6
gene id: 8478:MYF6
uniprot id: A0A8C3F2K5
names: Subcellular Location Annotation
messages: Nucleus

8478:PARP11
gene id: 8478:PARP11
uniprot id: A0A8C3FRY6
uniprot id: A0A8C3FUE9
names: Similarity
messages: Belongs to the ARTD/PARP family.

8478:ONECUT2
gene id: 8478:ONECUT2
uniprot id: A0A8C3PEI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8478:NMUR2
gene id: 8478:NMUR2
uniprot id: A0A8C3FST8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

8478:LETMD1
gene id: 8478:LETMD1
uniprot id: A0A8C3HZQ9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

8478:GHRHR
gene id: 8478:GHRHR
uniprot id: A0A8C3H749
names: Subcellular Location Annotation
messages: Membrane

8478:MAP4K3
gene id: 8478:MAP4K3
uniprot id: A0A8C3IFZ2
uniprot id: A0A8C3IJA5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

8478:BTF3L4
gene id: 8478:BTF3L4
uniprot id: A0A8C3HKZ6
names: Similarity
messages: Belongs to the NAC-beta family.

8478:FGF4
gene id: 8478:FGF4
uniprot id: A0A8C3HCQ2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8478:PANX2
gene id: 8478:PANX2
uniprot id: A0A8C3I8X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8478:SERPINI2
gene id: 8478:SERPINI2
uniprot id: A0A8C3HRZ2
names: Similarity
messages: Belongs to the serpin family.

8478:KLC2
gene id: 8478:KLC2
uniprot id: A0A8C3IF50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8478:ASPH
gene id: 8478:ASPH
uniprot id: A0A8C3IA39
uniprot id: A0A8C3IA50
uniprot id: A0A8C3IBK1
uniprot id: A0A8C3IBP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

8478:LOC101954181
gene id: 8478:LOC101954181
uniprot id: A0A8C3FC61
names: Similarity
messages: Belongs to the amidase family.

8478:MAN1A2
gene id: 8478:MAN1A2
uniprot id: A0A8C3EZZ1
uniprot id: A0A8C3F090
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8478:SIAH2
gene id: 8478:SIAH2
uniprot id: A0A8C3P9S0
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

8478:MCM6
gene id: 8478:MCM6
uniprot id: A0A8C3FVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

8478:COQ8A
gene id: 8478:COQ8A
uniprot id: A0A8C3P2U3
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8478:FGF3
gene id: 8478:FGF3
uniprot id: A0A8C3P2I7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8478:SPATS2L
gene id: 8478:SPATS2L
uniprot id: A0A8C3HCN6
names: Similarity
messages: Belongs to the SPATS2 family.

8478:GFM1
gene id: 8478:GFM1
uniprot id: A0A8C3I0L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

8478:LOC101933863
gene id: 8478:LOC101933863
uniprot id: A0A8C3P7Z6
names: Similarity
messages: Belongs to the multicopper oxidase family.

8478:A4GALT
gene id: 8478:A4GALT
uniprot id: A0A8C3IMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

8478:TSPAN18
gene id: 8478:TSPAN18
uniprot id: A0A8C3HF66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:CANX
gene id: 8478:CANX
uniprot id: A0A8C3FRD6
names: Similarity
messages: Belongs to the calreticulin family.

8478:VTA1
gene id: 8478:VTA1
uniprot id: A0A8C3HXN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

8478:LOC101949585
gene id: 8478:LOC101949585
uniprot id: A0A8C3INE0
names: Subcellular Location Annotation
messages: Nucleus

8478:VHL
gene id: 8478:VHL
uniprot id: A0A8C3HMC9
names: Similarity
messages: Belongs to the VHL family.

8478:IRF6
gene id: 8478:IRF6
uniprot id: A0A8C3I8W7
names: Subcellular Location Annotation
messages: Nucleus

8478:HDDC2
gene id: 8478:HDDC2
uniprot id: A0A8C3I0B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

8478:STRN
gene id: 8478:STRN
uniprot id: A0A8C3IIQ7
uniprot id: A0A8C3IIQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

8478:SCD
gene id: 8478:SCD
uniprot id: A0A8C3I6H4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

8478:JPH1
gene id: 8478:JPH1
uniprot id: A0A8C3FHG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8478:NPTX2
gene id: 8478:NPTX2
uniprot id: A0A8C3I5E6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:NR4A3
gene id: 8478:NR4A3
uniprot id: A0A8C3F774
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8478:CORO7
gene id: 8478:CORO7
uniprot id: A0A8C3IU55
names: Similarity
messages: Belongs to the WD repeat coronin family.

8478:LOC101934351
gene id: 8478:LOC101934351
uniprot id: A0A8C3H576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8478:EPHA4
gene id: 8478:EPHA4
uniprot id: A0A8C3I446
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

8478:SLC37A3
gene id: 8478:SLC37A3
uniprot id: A0A8C3HCU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8478:UNKL
gene id: 8478:UNKL
uniprot id: A0A8C3F771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

8478:LOC101944783
gene id: 8478:LOC101944783
uniprot id: A0A8C3HYC8
names: Similarity
messages: Belongs to the peptidase A1 family.

8478:C2H18orf21
gene id: 8478:C2H18orf21
uniprot id: A0A8C3H6D3
names: Similarity
messages: Belongs to the UPF0711 family.

8478:CTNND1
gene id: 8478:CTNND1
uniprot id: A0A8C3HUV3
names: Similarity
messages: Belongs to the beta-catenin family.

8478:EPC1
gene id: 8478:EPC1
uniprot id: A0A8C3HUN4
uniprot id: A0A8C3HUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

8478:CRELD2
gene id: 8478:CRELD2
uniprot id: A0A8C3I8J2
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:CIBAR2
gene id: 8478:CIBAR2
uniprot id: A0A8C3PD15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole

8478:ANKRD13C
gene id: 8478:ANKRD13C
uniprot id: A0A8C3PC99
names: Subcellular Location Annotation
messages: Membrane

8478:C4H6orf89
gene id: 8478:C4H6orf89
uniprot id: A0A8C3PEB4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8478:OPN5
gene id: 8478:OPN5
uniprot id: A0A8C3IDC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8478:LOC101938654
gene id: 8478:LOC101938654
uniprot id: A0A8C3FRK3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8478:GJA1
gene id: 8478:GJA1
uniprot id: A0A8C3I083
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8478:LOC101942784
gene id: 8478:LOC101942784
uniprot id: A0A8C3IHX9
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8478:AACS
gene id: 8478:AACS
uniprot id: A0A8C3INU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

8478:STAM
gene id: 8478:STAM
uniprot id: A0A8C3HND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

8478:EVX1
gene id: 8478:EVX1
uniprot id: A0A8C3IDU3
names: Subcellular Location Annotation
messages: Nucleus

8478:CDKN2AIPNL
gene id: 8478:CDKN2AIPNL
uniprot id: A0A8C3FJJ4
names: Similarity
messages: Belongs to the CARF family.

8478:LOC101932491
gene id: 8478:LOC101932491
uniprot id: A0A8C3I8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8478:TJP2
gene id: 8478:TJP2
uniprot id: A0A8C3INU0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

8478:APPL1
gene id: 8478:APPL1
uniprot id: A0A8C3HE40
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

8478:CNOT8
gene id: 8478:CNOT8
uniprot id: A0A8C3F3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8478:TNFAIP3
gene id: 8478:TNFAIP3
uniprot id: A0A8C3HYV0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8478:USB1
gene id: 8478:USB1
uniprot id: A0A8C3IUA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. USB1 family.
messages: Nucleus
messages: Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.

8478:LOC101934873
gene id: 8478:LOC101934873
uniprot id: A0A8C3HRN1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:NR5A1
gene id: 8478:NR5A1
uniprot id: A0A8C3IX01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

8478:DYM
gene id: 8478:DYM
uniprot id: A0A8C3IPY2
uniprot id: A0A8C3PEK9
names: Similarity
messages: Belongs to the dymeclin family.

8478:HSPA9
gene id: 8478:HSPA9
uniprot id: A0A8C3PBF2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8478:EXTL3
gene id: 8478:EXTL3
uniprot id: A0A8C3PAH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8478:PARVG
gene id: 8478:PARVG
uniprot id: A0A8C3IMR7
uniprot id: A0A8C3INL4
names: Similarity
messages: Belongs to the parvin family.

8478:NDUFS8
gene id: 8478:NDUFS8
uniprot id: A0A8C3HV95
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

8478:MKX
gene id: 8478:MKX
uniprot id: A0A8C3HRL7
names: Subcellular Location Annotation
messages: Nucleus

8478:GABRG1
gene id: 8478:GABRG1
uniprot id: A0A8C3IX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8478:GABRA6
gene id: 8478:GABRA6
uniprot id: A0A8C3FLV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8478:FAM3C
gene id: 8478:FAM3C
uniprot id: A0A8C3FLD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8478:NDUFB4
gene id: 8478:NDUFB4
uniprot id: A0A8C3F4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8478:ZDHHC9
gene id: 8478:ZDHHC9
uniprot id: A0A8C3HDA4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:DDC
gene id: 8478:DDC
uniprot id: A0A8C3P881
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8478:LOC101940193
gene id: 8478:LOC101940193
uniprot id: A0A8C3HMR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8478:KDM4A
gene id: 8478:KDM4A
uniprot id: A0A8C3F6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

8478:SENP6
gene id: 8478:SENP6
uniprot id: A0A8C3II16
uniprot id: A0A8C3II26
uniprot id: A0A8C3IIU3
names: Similarity
messages: Belongs to the peptidase C48 family.

8478:DARS1
gene id: 8478:DARS1
uniprot id: A0A8C3FSJ0
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

8478:WARS2
gene id: 8478:WARS2
uniprot id: A0A8C3F1K2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8478:HESX1
gene id: 8478:HESX1
uniprot id: A0A8C3P3Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

8478:ESRRG
gene id: 8478:ESRRG
uniprot id: A0A8C3P551
uniprot id: A0A8C3P559
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8478:MFN1
gene id: 8478:MFN1
uniprot id: A0A8C3IWE4
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8478:NDUFAF1
gene id: 8478:NDUFAF1
uniprot id: A0A8C3HIL2
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

8478:VPS29
gene id: 8478:VPS29
uniprot id: A0A8C3H6U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

8478:ABCB10
gene id: 8478:ABCB10
uniprot id: A0A8C3H8H6
names: Subcellular Location Annotation
messages: Membrane

8478:GNB1
gene id: 8478:GNB1
uniprot id: A0A8C3PCL5
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8478:GRK3
gene id: 8478:GRK3
uniprot id: A0A8C3PBP4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8478:SLC16A2
gene id: 8478:SLC16A2
uniprot id: A0A8C3P755
names: Subcellular Location Annotation
messages: Membrane

8478:CCNJL
gene id: 8478:CCNJL
uniprot id: A0A8C3FSW9
names: Similarity
messages: Belongs to the cyclin family.

8478:LOC101946412
gene id: 8478:LOC101946412
uniprot id: A0A8C3P9L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

8478:GTF2A2
gene id: 8478:GTF2A2
uniprot id: A0A8C3HVQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

8478:MOV10
gene id: 8478:MOV10
uniprot id: A0A8C3I0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

8478:NPY
gene id: 8478:NPY
uniprot id: A0A8C3IC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

8478:CEBPA
gene id: 8478:CEBPA
uniprot id: A0A8C3F1M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

8478:FAM110C
gene id: 8478:FAM110C
uniprot id: A0A8C3IAK6
names: Similarity
messages: Belongs to the FAM110 family.

8478:XDH
gene id: 8478:XDH
uniprot id: A0A8C3HCT8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

8478:RPS27L
gene id: 8478:RPS27L
uniprot id: A0A8C3HYK3
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8478:YAP1
gene id: 8478:YAP1
uniprot id: A0A8C3IVI1
uniprot id: A0A8C3IVP7
uniprot id: A0A8C3IYC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

8478:LOC101952801
gene id: 8478:LOC101952801
uniprot id: A0A8C3I5F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

8478:CTLA4
gene id: 8478:CTLA4
uniprot id: A0A8C3FP00
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

8478:DIPK1B
gene id: 8478:DIPK1B
uniprot id: A0A8C3HDX7
uniprot id: A0A8C3HE53
names: Similarity
messages: Belongs to the DIPK family.

8478:FAM221A
gene id: 8478:FAM221A
uniprot id: A0A8C3ICX7
names: Similarity
messages: Belongs to the FAM221 family.

8478:DMAP1
gene id: 8478:DMAP1
uniprot id: A0A8C3F8F5
names: Subcellular Location Annotation
messages: Nucleus

8478:LOC101937200
gene id: 8478:LOC101937200
uniprot id: A0A8C3ILZ6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8478:CEP170
gene id: 8478:CEP170
uniprot id: A0A8C3FMZ2
uniprot id: A0A8C3FMZ8
uniprot id: A0A8C3FSY9
uniprot id: A0A8C3FVH4
names: Similarity
messages: Belongs to the CEP170 family.

8478:LOC101942201
gene id: 8478:LOC101942201
uniprot id: A0A8C3IAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

8478:SURF6
gene id: 8478:SURF6
uniprot id: A0A8C3I8B6
names: Similarity
messages: Belongs to the SURF6 family.

8478:SEPTIN2
gene id: 8478:SEPTIN2
uniprot id: A0A8C3F423
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

8478:RAB3GAP1
gene id: 8478:RAB3GAP1
uniprot id: A0A8C3FSV8
uniprot id: A0A8C3HB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm
messages: Endoplasmic reticulum

8478:APOA1
gene id: 8478:APOA1
uniprot id: A0A8C3PAS9
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8478:LOC101949854
gene id: 8478:LOC101949854
uniprot id: A0A8C3I1A6
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8478:LOC101936919
gene id: 8478:LOC101936919
uniprot id: A0A8C3FTI0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8478:USP13
gene id: 8478:USP13
uniprot id: A0A8C3ITV6
uniprot id: A0A8C3IUR7
names: Similarity
messages: Belongs to the peptidase C19 family.

8478:SLC39A9
gene id: 8478:SLC39A9
uniprot id: A0A8C3I9E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

8478:HDHD2
gene id: 8478:HDHD2
uniprot id: A0A8C3PEL9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8478:SEC22B
gene id: 8478:SEC22B
uniprot id: A0A8C3H7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8478:HSPD1
gene id: 8478:HSPD1
uniprot id: A0A8C3IDB3
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

8478:IL7
gene id: 8478:IL7
uniprot id: A0A8C3FIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-7/IL-9 family.
messages: Secreted

8478:KATNB1
gene id: 8478:KATNB1
uniprot id: A0A8C3IST6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

8478:ARL2
gene id: 8478:ARL2
uniprot id: A0A8C3PD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8478:PAX3
gene id: 8478:PAX3
uniprot id: A0A8C3I2G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8478:C8H5orf24
gene id: 8478:C8H5orf24
uniprot id: A0A8C3FQR4
names: Similarity
messages: Belongs to the UPF0461 family.

8478:LOC101931395
gene id: 8478:LOC101931395
uniprot id: A0A8C3ICK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8478:GPR50
gene id: 8478:GPR50
uniprot id: A0A8C3IAD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:TEK
gene id: 8478:TEK
uniprot id: A0A8C3FL05
uniprot id: A0A8C3H971
uniprot id: A0A8C3H9M0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:PALS2
gene id: 8478:PALS2
uniprot id: A0A8C3ICT2
names: Similarity
messages: Belongs to the MAGUK family.

8478:COQ7
gene id: 8478:COQ7
uniprot id: A0A8C3FWP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

8478:SLC16A4
gene id: 8478:SLC16A4
uniprot id: A0A8C3F4B8
names: Subcellular Location Annotation
messages: Membrane

8478:LOC101935180
gene id: 8478:LOC101935180
uniprot id: A0A8C3FUT6
uniprot id: A0A8C3FW30
names: Subcellular Location Annotation
messages: Cytoplasm

8478:THG1L
gene id: 8478:THG1L
uniprot id: A0A8C3F332
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

8478:FAM135A
gene id: 8478:FAM135A
uniprot id: A0A8C3II53
uniprot id: A0A8C3ILS7
names: Similarity
messages: Belongs to the FAM135 family.

8478:SLC35A5
gene id: 8478:SLC35A5
uniprot id: A0A8C3F8L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8478:PIK3CA
gene id: 8478:PIK3CA
uniprot id: A0A8C3ITR8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8478:HOXA1
gene id: 8478:HOXA1
uniprot id: A0A8C3ICB0
names: Subcellular Location Annotation
messages: Nucleus

8478:SHROOM1
gene id: 8478:SHROOM1
uniprot id: A0A8C3HT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

8478:ADIPOR2
gene id: 8478:ADIPOR2
uniprot id: A0A8C3IUF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8478:LOC101936400
gene id: 8478:LOC101936400
uniprot id: A0A8C3I3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8478:TJAP1
gene id: 8478:TJAP1
uniprot id: A0A8C3IQ47
names: Subcellular Location Annotation
messages: Membrane

8478:DNER
gene id: 8478:DNER
uniprot id: A0A8C3I457
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:SLC6A1
gene id: 8478:SLC6A1
uniprot id: A0A8C3F628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8478:GADD45A
gene id: 8478:GADD45A
uniprot id: A0A8C3F3T7
names: Similarity
messages: Belongs to the GADD45 family.

8478:LOC101941478
gene id: 8478:LOC101941478
uniprot id: A0A8C3IDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

8478:TMCO4
gene id: 8478:TMCO4
uniprot id: A0A8C3IJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO4 family.
messages: Membrane

8478:UBE2B
gene id: 8478:UBE2B
uniprot id: A0A8C3FKP6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8478:LOC101943564
gene id: 8478:LOC101943564
uniprot id: A0A8C3PBE3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

8478:LOC101949927
gene id: 8478:LOC101949927
uniprot id: A0A8C3HD73
names: Subcellular Location Annotation
messages: Membrane

8478:TMEM132B
gene id: 8478:TMEM132B
uniprot id: A0A8C3INT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8478:CLP1
gene id: 8478:CLP1
uniprot id: A0A8C3HWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

8478:TUT4
gene id: 8478:TUT4
uniprot id: A0A8C3HN05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

8478:CD81
gene id: 8478:CD81
uniprot id: A0A8C3I7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:PDE7A
gene id: 8478:PDE7A
uniprot id: A0A8C3I987
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8478:ACTR3B
gene id: 8478:ACTR3B
uniprot id: A0A8C3HYM7
names: Similarity
messages: Belongs to the actin family.

8478:LOC101949949
gene id: 8478:LOC101949949
uniprot id: A0A8C3HML3
uniprot id: A0A8C3P6Z9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

8478:TRPC5
gene id: 8478:TRPC5
uniprot id: A0A8C3HW10
names: Subcellular Location Annotation
messages: Membrane

8478:LOC101951164
gene id: 8478:LOC101951164
uniprot id: A0A8C3FHL2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8478:DNAI7
gene id: 8478:DNAI7
uniprot id: A0A8C3FUD0
names: Similarity
messages: Belongs to the DNAI7 family.

8478:TFB1M
gene id: 8478:TFB1M
uniprot id: A0A8C3P845
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

8478:SFT2D2
gene id: 8478:SFT2D2
uniprot id: A0A8C3H762
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

8478:TTC38
gene id: 8478:TTC38
uniprot id: A0A8C3PDK3
names: Similarity
messages: Belongs to the TTC38 family.

8478:CPVL
gene id: 8478:CPVL
uniprot id: A0A8C3IGF9
names: Similarity
messages: Belongs to the peptidase S10 family.

8478:P2RX7
gene id: 8478:P2RX7
uniprot id: A0A8C3IT09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P2X receptor family.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8478:KCNC4
gene id: 8478:KCNC4
uniprot id: A0A8C3F2I4
uniprot id: A0A8C3F2L7
uniprot id: A0A8C3F2U0
names: Subcellular Location Annotation
messages: Membrane

8478:LOC101941450
gene id: 8478:LOC101941450
uniprot id: A0A8C3IXB7
uniprot id: A0A8C3J1I4
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8478:C20H9orf78
gene id: 8478:C20H9orf78
uniprot id: A0A8C3IEL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TLS1 family.
messages: Nucleus

8478:LEPROT
gene id: 8478:LEPROT
uniprot id: A0A8C3F5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

8478:SDR42E1
gene id: 8478:SDR42E1
uniprot id: A0A8C3IHV8
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8478:CD99L2
gene id: 8478:CD99L2
uniprot id: A0A8C3I7A0
uniprot id: A0A8C3I850
names: Similarity
messages: Belongs to the CD99 family.

8478:TAGLN
gene id: 8478:TAGLN
uniprot id: A0A8C3I5W6
names: Similarity
messages: Belongs to the calponin family.

8478:NMD3
gene id: 8478:NMD3
uniprot id: A0A8C3I0H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

8478:NDUFB5
gene id: 8478:NDUFB5
uniprot id: A0A8C3IWF5
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

8478:ENTPD3
gene id: 8478:ENTPD3
uniprot id: A0A8C3IGE8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8478:LOC101939806
gene id: 8478:LOC101939806
uniprot id: A0A8C3IVT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

8478:LOC101932518
gene id: 8478:LOC101932518
uniprot id: A0A8C3IGP1
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8478:GKAP1
gene id: 8478:GKAP1
uniprot id: A0A8C3IR77
names: Similarity
messages: Belongs to the GKAP1 family.

8478:IMPA1
gene id: 8478:IMPA1
uniprot id: A0A8C3H9E1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8478:NID1
gene id: 8478:NID1
uniprot id: A0A8C3F9L8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8478:ZNF830
gene id: 8478:ZNF830
uniprot id: A0A8C3F141
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

8478:MMAB
gene id: 8478:MMAB
uniprot id: A0A8C3IAG5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

8478:SLC2A6
gene id: 8478:SLC2A6
uniprot id: A0A8C3PBC9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8478:LTBP1
gene id: 8478:LTBP1
uniprot id: A0A8C3IPZ0
uniprot id: A0A8C3PE81
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8478:GPR158
gene id: 8478:GPR158
uniprot id: A0A8C3HPX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8478:ATP23
gene id: 8478:ATP23
uniprot id: A0A8C3P6P2
names: Similarity
messages: Belongs to the peptidase M76 family.

8478:MED27
gene id: 8478:MED27
uniprot id: A0A8C3IAX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

8478:LOC101944140
gene id: 8478:LOC101944140
uniprot id: A0A8C3I2P3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:LOC101934464
gene id: 8478:LOC101934464
uniprot id: A0A8C3HHI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

8478:SGO1
gene id: 8478:SGO1
uniprot id: A0A8C3IE38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

8478:DDX20
gene id: 8478:DDX20
uniprot id: A0A8C3I9M1
names: Similarity
messages: Belongs to the DEAD box helicase family.

8478:PLOD2
gene id: 8478:PLOD2
uniprot id: A0A8C3HCM6
uniprot id: A0A8C3P2L0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8478:ESR1
gene id: 8478:ESR1
uniprot id: A0A8C3P889
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

8478:LAPTM4A
gene id: 8478:LAPTM4A
uniprot id: A0A8C3I4I8
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

8478:GALNT15
gene id: 8478:GALNT15
uniprot id: A0A8C3IFN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8478:USP22
gene id: 8478:USP22
uniprot id: A0A8C3I8C2
uniprot id: A0A8C3I9T1
names: Similarity
messages: Belongs to the peptidase C19 family.

8478:AIDA
gene id: 8478:AIDA
uniprot id: A0A8C3HEN8
names: Similarity
messages: Belongs to the AIDA family.

8478:WNT5A
gene id: 8478:WNT5A
uniprot id: A0A8C3I9A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8478:KAT2B
gene id: 8478:KAT2B
uniprot id: A0A8C3PCC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

8478:BCHE
gene id: 8478:BCHE
uniprot id: A0A8C3HS26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

8478:SLC37A1
gene id: 8478:SLC37A1
uniprot id: A0A8C3FLW3
uniprot id: A0A8C3FQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8478:SLC25A48
gene id: 8478:SLC25A48
uniprot id: A0A8C3FQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8478:TIMP4
gene id: 8478:TIMP4
uniprot id: A0A8C3IQH9
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8478:LOC101942818
gene id: 8478:LOC101942818
uniprot id: A0A8C3IQK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

8478:ARL6
gene id: 8478:ARL6
uniprot id: A0A8C3H7X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

8478:TMOD2
gene id: 8478:TMOD2
uniprot id: A0A8C3IXN3
names: Subcellular Location Annotation
messages: cytoskeleton

8478:ZNRF3
gene id: 8478:ZNRF3
uniprot id: A0A8C3IXK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

8478:SYPL1
gene id: 8478:SYPL1
uniprot id: A0A8C3F1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8478:UPP1
gene id: 8478:UPP1
uniprot id: A0A8C3HT69
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

8478:PARP1
gene id: 8478:PARP1
uniprot id: A0A8C3HD04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

8478:TFPI2
gene id: 8478:TFPI2
uniprot id: A0A8C3IJA9
names: Subcellular Location Annotation
messages: Secreted

8478:SCN3B
gene id: 8478:SCN3B
uniprot id: A0A8C3HNU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

8478:WNT7B
gene id: 8478:WNT7B
uniprot id: A0A8C3PDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8478:CLCN6
gene id: 8478:CLCN6
uniprot id: A0A8C3IC44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

8478:IDNK
gene id: 8478:IDNK
uniprot id: A0A8C3IPA3
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

8478:PRPSAP2
gene id: 8478:PRPSAP2
uniprot id: A0A8C3I8R2
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8478:FICD
gene id: 8478:FICD
uniprot id: A0A8C3FGH0
names: Similarity
messages: Belongs to the fic family.

8478:LOC101942869
gene id: 8478:LOC101942869
uniprot id: A0A8C3HHS3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8478:GRHL1
gene id: 8478:GRHL1
uniprot id: A0A8C3HK22
names: Subcellular Location Annotation
messages: Nucleus

8478:DIPK2A
gene id: 8478:DIPK2A
uniprot id: A0A8C3HCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

8478:PLCB4
gene id: 8478:PLCB4
uniprot id: A0A8C3PCW5
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

8478:TBX22
gene id: 8478:TBX22
uniprot id: A0A8C3HLH7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8478:LOC103306138
gene id: 8478:LOC103306138
uniprot id: A0A8C3FLD0
names: Similarity
messages: Belongs to the thioredoxin family.

8478:SLC9A3R2
gene id: 8478:SLC9A3R2
uniprot id: A0A8C3F180
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

8478:LMBR1
gene id: 8478:LMBR1
uniprot id: A0A8C3HYK2
names: Similarity
messages: Belongs to the LIMR family.

8478:CBL
gene id: 8478:CBL
uniprot id: A0A8C3H9K6
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

8478:ST8SIA1
gene id: 8478:ST8SIA1
uniprot id: A0A8C3FPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8478:LOC101946021
gene id: 8478:LOC101946021
uniprot id: A0A8C3IEA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

8478:ZC3H12B
gene id: 8478:ZC3H12B
uniprot id: A0A8C3FIL6
names: Similarity
messages: Belongs to the ZC3H12 family.

8478:MMD2
gene id: 8478:MMD2
uniprot id: A0A8C3PB43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8478:DLGAP1
gene id: 8478:DLGAP1
uniprot id: A0A8C3FH76
uniprot id: A0A8C3FH92
uniprot id: A0A8C3FML8
names: Similarity
messages: Belongs to the SAPAP family.

8478:SLU7
gene id: 8478:SLU7
uniprot id: A0A8C3H9P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

8478:TRPC1
gene id: 8478:TRPC1
uniprot id: A0A8C3FP77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

8478:NCOA7
gene id: 8478:NCOA7
uniprot id: A0A8C3HZM6
uniprot id: A0A8C3I175
names: Similarity
messages: Belongs to the OXR1 family.

8478:DENND11
gene id: 8478:DENND11
uniprot id: A0A8C3P2C1
names: Similarity
messages: Belongs to the DENND11 family.

8478:ORC2
gene id: 8478:ORC2
uniprot id: A0A8C3HCC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

8478:B9D1
gene id: 8478:B9D1
uniprot id: A0A8C3I8U7
names: Subcellular Location Annotation
messages: cilium basal body

8478:LAMA1
gene id: 8478:LAMA1
uniprot id: A0A8C3FH91
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8478:MLST8
gene id: 8478:MLST8
uniprot id: A0A8C3F246
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of TORC1 complex. Part of the TORC2 complex.
messages: Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.

8478:ATP6V0C
gene id: 8478:ATP6V0C
uniprot id: A0A8C3IEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

8478:TM9SF3
gene id: 8478:TM9SF3
uniprot id: A0A8C3FUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8478:OPRM1
gene id: 8478:OPRM1
uniprot id: A0A8C3HUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

8478:BARX2
gene id: 8478:BARX2
uniprot id: A0A8C3ITS8
names: Subcellular Location Annotation
messages: Nucleus

8478:SLC35F2
gene id: 8478:SLC35F2
uniprot id: A0A8C3I2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

8478:WNT2B
gene id: 8478:WNT2B
uniprot id: A0A8C3I9H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8478:DNASE1L3
gene id: 8478:DNASE1L3
uniprot id: A0A8C3HKV0
names: Similarity
messages: Belongs to the DNase I family.

8478:PSMD7
gene id: 8478:PSMD7
uniprot id: A0A8C3IUN3
names: Similarity
messages: Belongs to the peptidase M67A family.

8478:LOC101947136
gene id: 8478:LOC101947136
uniprot id: A0A8C3HRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:RELT
gene id: 8478:RELT
uniprot id: A0A8C3FUA0
names: Similarity
messages: Belongs to the RELT family.

8478:RPL18A
gene id: 8478:RPL18A
uniprot id: A0A8C3H5N4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

8478:NOP58
gene id: 8478:NOP58
uniprot id: A0A8C3HBV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

8478:CUEDC2
gene id: 8478:CUEDC2
uniprot id: A0A8C3PAX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

8478:COPB2
gene id: 8478:COPB2
uniprot id: A0A8C3I2U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

8478:PARP6
gene id: 8478:PARP6
uniprot id: A0A8C3FIW1
names: Similarity
messages: Belongs to the ARTD/PARP family.

8478:AGTR2
gene id: 8478:AGTR2
uniprot id: A0A8C3HUM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

8478:CDPF1
gene id: 8478:CDPF1
uniprot id: A0A8C3IJ94
names: Similarity
messages: Belongs to the CDPF1 family.

8478:BRS3
gene id: 8478:BRS3
uniprot id: A0A8C3IRF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

8478:BRI3
gene id: 8478:BRI3
uniprot id: A0A8C3I4K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

8478:DRD1
gene id: 8478:DRD1
uniprot id: A0A8C3FMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:NTMT2
gene id: 8478:NTMT2
uniprot id: A0A8C3P518
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

8478:SIKE1
gene id: 8478:SIKE1
uniprot id: A0A8C3HTT8
names: Similarity
messages: Belongs to the SIKE family.

8478:LOC101949462
gene id: 8478:LOC101949462
uniprot id: A0A8C3HXN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

8478:IGBP1
gene id: 8478:IGBP1
uniprot id: A0A8C3HLT9
names: Similarity
messages: Belongs to the IGBP1/TAP42 family.

8478:SIDT2
gene id: 8478:SIDT2
uniprot id: A0A8C3I5B0
uniprot id: A0A8C3I5L4
uniprot id: A0A8C3I6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

8478:NECTIN3
gene id: 8478:NECTIN3
uniprot id: A0A8C3FCE5
names: Similarity
messages: Belongs to the nectin family.

8478:NKD1
gene id: 8478:NKD1
uniprot id: A0A8C3HR94
uniprot id: A0A8C3HRA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

8478:ODF2L
gene id: 8478:ODF2L
uniprot id: A0A8C3IPT3
uniprot id: A0A8C3ISB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

8478:PLPP3
gene id: 8478:PLPP3
uniprot id: A0A8C3HL51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8478:MTMR9
gene id: 8478:MTMR9
uniprot id: A0A8C3I771
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8478:LOC101948426
gene id: 8478:LOC101948426
uniprot id: A0A8C3I4H9
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8478:UBXN1
gene id: 8478:UBXN1
uniprot id: A0A8C3HXH3
names: Subcellular Location Annotation
messages: Cytoplasm

8478:HSP90AB1
gene id: 8478:HSP90AB1
uniprot id: A0A8C3IQ97
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8478:LOC103305685
gene id: 8478:LOC103305685
uniprot id: A0A8C3HKV4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8478:PIK3CG
gene id: 8478:PIK3CG
uniprot id: A0A8C3F0Q0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8478:LOC101945053
gene id: 8478:LOC101945053
uniprot id: A0A8C3HVX7
names: Similarity
messages: Belongs to the peptidase A1 family.

8478:IRF2BP2
gene id: 8478:IRF2BP2
uniprot id: A0A8C3H855
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

8478:PSMA2
gene id: 8478:PSMA2
uniprot id: A0A8C3IL10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8478:SLC16A7
gene id: 8478:SLC16A7
uniprot id: A0A8C3HKW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8478:RAB43
gene id: 8478:RAB43
uniprot id: A0A8C3IS89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

8478:LOC101946611
gene id: 8478:LOC101946611
uniprot id: A0A8C3FHY0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:CCDC93
gene id: 8478:CCDC93
uniprot id: A0A8C3FTP5
names: Similarity
messages: Belongs to the CCDC93 family.

8478:NXF1
gene id: 8478:NXF1
uniprot id: A0A8C3IHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

8478:CUL4B
gene id: 8478:CUL4B
uniprot id: A0A8C3HG66
names: Similarity
messages: Belongs to the cullin family.

8478:ITPKB
gene id: 8478:ITPKB
uniprot id: A0A8C3HD17
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8478:KCNT1
gene id: 8478:KCNT1
uniprot id: A0A8C3P369
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8478:LOC101947813
gene id: 8478:LOC101947813
uniprot id: A0A8C3F4Z5
names: Subcellular Location Annotation
messages: Membrane

8478:CHMP1B
gene id: 8478:CHMP1B
uniprot id: A0A8C3HLJ6
names: Similarity
messages: Belongs to the SNF7 family.

8478:LOC101936107
gene id: 8478:LOC101936107
uniprot id: A0A8C3IMP7
names: Similarity
messages: Belongs to the TTC38 family.

8478:IGF2BP2
gene id: 8478:IGF2BP2
uniprot id: A0A8C3FIF3
uniprot id: A0A8C3H997
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Cytoplasm

8478:PTGS1
gene id: 8478:PTGS1
uniprot id: A0A8C3FSF4
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:TMEM120B
gene id: 8478:TMEM120B
uniprot id: A0A8C3IQI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

8478:EDEM3
gene id: 8478:EDEM3
uniprot id: A0A8C3HS37
uniprot id: A0A8C3P7P4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8478:SHCBP1L
gene id: 8478:SHCBP1L
uniprot id: A0A8C3HRH4
names: Subcellular Location Annotation
messages: spindle

8478:BEND6
gene id: 8478:BEND6
uniprot id: A0A8C3ICS6
names: Subcellular Location Annotation
messages: Nucleus

8478:CNKSR3
gene id: 8478:CNKSR3
uniprot id: A0A8C3HTJ4
names: Similarity
messages: Belongs to the CNKSR family.

8478:SUCNR1
gene id: 8478:SUCNR1
uniprot id: A0A8C3P9R1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:SULF1
gene id: 8478:SULF1
uniprot id: A0A8C3FM27
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8478:DYNLT2
gene id: 8478:DYNLT2
uniprot id: A0A8C3HEP6
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8478:TMEM88B
gene id: 8478:TMEM88B
uniprot id: A0A8C3IGU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

8478:MRPL19
gene id: 8478:MRPL19
uniprot id: A0A8C3IAX5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

8478:ORC6
gene id: 8478:ORC6
uniprot id: A0A8C3HRS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

8478:GNAL
gene id: 8478:GNAL
uniprot id: A0A8C3IZX9
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

8478:LTBP3
gene id: 8478:LTBP3
uniprot id: A0A8C3IJX1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8478:PARVB
gene id: 8478:PARVB
uniprot id: A0A8C3IMW2
uniprot id: A0A8C3IQE8
names: Similarity
messages: Belongs to the parvin family.

8478:MYO3A
gene id: 8478:MYO3A
uniprot id: A0A8C3HPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

8478:SMAD5
gene id: 8478:SMAD5
uniprot id: A0A8C3FMR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8478:LOC101932600
gene id: 8478:LOC101932600
uniprot id: A0A8C3I0T1
names: Similarity
messages: Belongs to the alpha-actinin family.

8478:DMRTB1
gene id: 8478:DMRTB1
uniprot id: A0A8C3F7E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8478:DLL1
gene id: 8478:DLL1
uniprot id: A0A8C3HEU3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8478:ABL2
gene id: 8478:ABL2
uniprot id: A0A8C3HLH5
uniprot id: A0A8C3HLJ3
uniprot id: A0A8C3HM27
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8478:TAF1B
gene id: 8478:TAF1B
uniprot id: A0A8C3HL36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

8478:SLC9A9
gene id: 8478:SLC9A9
uniprot id: A0A8C3P2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

8478:ARFGEF1
gene id: 8478:ARFGEF1
uniprot id: A0A8C3HJX4
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

8478:PDE3A
gene id: 8478:PDE3A
uniprot id: A0A8C3FPM1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8478:DAO
gene id: 8478:DAO
uniprot id: A0A8C3FM66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

8478:ATP1A1
gene id: 8478:ATP1A1
uniprot id: A0A8C3F4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

8478:SCARB1
gene id: 8478:SCARB1
uniprot id: A0A8C3ILS0
names: Similarity
messages: Belongs to the CD36 family.

8478:SHMT1
gene id: 8478:SHMT1
uniprot id: A0A8C3IB37
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

8478:HACD4
gene id: 8478:HACD4
uniprot id: A0A8C3I140
uniprot id: A0A8C3I148
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:ACSL3
gene id: 8478:ACSL3
uniprot id: A0A8C3I268
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8478:TEKT4
gene id: 8478:TEKT4
uniprot id: A0A8C3I812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8478:RFTN1
gene id: 8478:RFTN1
uniprot id: A0A8C3ICI1
uniprot id: A0A8C3IFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

8478:XPR1
gene id: 8478:XPR1
uniprot id: A0A8C3ITB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

8478:PRDM12
gene id: 8478:PRDM12
uniprot id: A0A8C3IDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

8478:LOC101948839
gene id: 8478:LOC101948839
uniprot id: A0A8C3IV23
names: Similarity
messages: Belongs to the cytochrome b5 family.

8478:SEC61A1
gene id: 8478:SEC61A1
uniprot id: A0A8C3HL57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:LOC101939800
gene id: 8478:LOC101939800
uniprot id: A0A8C3ID29
names: Subcellular Location Annotation
messages: Membrane

8478:CHMP4C
gene id: 8478:CHMP4C
uniprot id: A0A8C3H9T6
names: Similarity
messages: Belongs to the SNF7 family.

8478:ITPKA
gene id: 8478:ITPKA
uniprot id: A0A8C3HIG3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8478:KMT5A
gene id: 8478:KMT5A
uniprot id: A0A8C3IU24
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8478:CDKN1B
gene id: 8478:CDKN1B
uniprot id: A0A8C3EZY6
names: Similarity
messages: Belongs to the CDI family.

8478:RRP36
gene id: 8478:RRP36
uniprot id: A0A8C3F907
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

8478:ECHDC2
gene id: 8478:ECHDC2
uniprot id: A0A8C3EZA4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8478:PML
gene id: 8478:PML
uniprot id: A0A8C3HA38
names: Subcellular Location Annotation
messages: Cytoplasm

8478:LOC101941670
gene id: 8478:LOC101941670
uniprot id: A0A8C3HHH9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8478:MOGAT1
gene id: 8478:MOGAT1
uniprot id: A0A8C3PA60
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:STAG2
gene id: 8478:STAG2
uniprot id: A0A8C3P752
names: Similarity
messages: Belongs to the SCC3 family.

8478:LOC101944509
gene id: 8478:LOC101944509
uniprot id: A0A8C3HWH0
names: Similarity
messages: Belongs to the peptidase A1 family.

8478:LOC101935542
gene id: 8478:LOC101935542
uniprot id: A0A8C3I9J9
names: Similarity
messages: Belongs to the actin family.

8478:TMEM11
gene id: 8478:TMEM11
uniprot id: A0A8C3I7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Plays a role in mitochondrial morphogenesis.

8478:IRX4
gene id: 8478:IRX4
uniprot id: A0A8C3HRL0
uniprot id: A0A8C3HSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8478:ANO6
gene id: 8478:ANO6
uniprot id: A0A8C3HP98
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:LOC101937031
gene id: 8478:LOC101937031
uniprot id: A0A8C3HLC6
names: Similarity
messages: Belongs to the IAP family.

8478:HMCES
gene id: 8478:HMCES
uniprot id: A0A8C3HLK0
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

8478:TRH
gene id: 8478:TRH
uniprot id: A0A8C3HM09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

8478:DCBLD1
gene id: 8478:DCBLD1
uniprot id: A0A8C3I0L5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:KLHL3
gene id: 8478:KLHL3
uniprot id: A0A8C3FNU0
uniprot id: A0A8C3FSQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KLHL3 family.
messages: cytoskeleton
messages: cytosol

8478:RPL26L1
gene id: 8478:RPL26L1
uniprot id: A0A8C3FK30
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

8478:NADK
gene id: 8478:NADK
uniprot id: A0A8C3IFA8
names: Similarity
messages: Belongs to the NAD kinase family.

8478:SPTBN2
gene id: 8478:SPTBN2
uniprot id: A0A8C3IIA2
names: Similarity
messages: Belongs to the spectrin family.

8478:MARK2
gene id: 8478:MARK2
uniprot id: A0A8C3IGE9
uniprot id: A0A8C3IJ18
uniprot id: A0A8C3PD07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8478:SSU72
gene id: 8478:SSU72
uniprot id: A0A8C3IEJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

8478:LOC101945284
gene id: 8478:LOC101945284
uniprot id: A0A8C3IB61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8478:DESI2
gene id: 8478:DESI2
uniprot id: A0A8C3FUV5
names: Similarity
messages: Belongs to the DeSI family.

8478:FBXO45
gene id: 8478:FBXO45
uniprot id: A0A8C3I933
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

8478:ST7
gene id: 8478:ST7
uniprot id: A0A8C3FLJ3
uniprot id: A0A8C3FLK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

8478:PACSIN2
gene id: 8478:PACSIN2
uniprot id: A0A8C3IQ36
uniprot id: A0A8C3PE55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

8478:IGFLR1
gene id: 8478:IGFLR1
uniprot id: A0A8C3H5W4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:CCND3
gene id: 8478:CCND3
uniprot id: A0A8C3HWG2
names: Similarity
messages: Belongs to the cyclin family.

8478:ACAA1
gene id: 8478:ACAA1
uniprot id: A0A8C3HZI7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8478:ATG4A
gene id: 8478:ATG4A
uniprot id: A0A8C3F038
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8478:SYNDIG1
gene id: 8478:SYNDIG1
uniprot id: A0A8C3FZ35
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8478:FOXJ2
gene id: 8478:FOXJ2
uniprot id: A0A8C3HAI8
names: Subcellular Location Annotation
messages: Nucleus

8478:EXOC8
gene id: 8478:EXOC8
uniprot id: A0A8C3FF21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

8478:SGK1
gene id: 8478:SGK1
uniprot id: A0A8C3HXC3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:CNPY1
gene id: 8478:CNPY1
uniprot id: A0A8C3HYR2
names: Similarity
messages: Belongs to the canopy family.

8478:RAB32
gene id: 8478:RAB32
uniprot id: A0A8C3P8C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8478:DYNC1LI1
gene id: 8478:DYNC1LI1
uniprot id: A0A8C3IDT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

8478:WSCD2
gene id: 8478:WSCD2
uniprot id: A0A8C3FJY9
names: Function
names: Similarity
messages: Belongs to the WSCD family.
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

8478:CEMIP2
gene id: 8478:CEMIP2
uniprot id: A0A8C3I6Y9
names: Similarity
messages: Belongs to the CEMIP family.

8478:LOC101943877
gene id: 8478:LOC101943877
uniprot id: A0A8C3PA20
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:NUSAP1
gene id: 8478:NUSAP1
uniprot id: A0A8C3HI33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

8478:LOC101944657
gene id: 8478:LOC101944657
uniprot id: A0A8C3FL26
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8478:TTYH3
gene id: 8478:TTYH3
uniprot id: A0A8C3I6Y3
uniprot id: A0A8C3I708
uniprot id: A0A8C3IA21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8478:ILDR2
gene id: 8478:ILDR2
uniprot id: A0A8C3FEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8478:RPL22L1
gene id: 8478:RPL22L1
uniprot id: A0A8C3HRF8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

8478:EOGT
gene id: 8478:EOGT
uniprot id: A0A8C3H585
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

8478:CRHR2
gene id: 8478:CRHR2
uniprot id: A0A8C3I2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

8478:CSNK1A1
gene id: 8478:CSNK1A1
uniprot id: A0A8C3FKN6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:LOC101953972
gene id: 8478:LOC101953972
uniprot id: A0A8C3FAJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8478:FUBP3
gene id: 8478:FUBP3
uniprot id: A0A8C3IDH6
uniprot id: A0A8C3IFU7
uniprot id: A0A8C3IFV7
uniprot id: A0A8C3PCE2
names: Subcellular Location Annotation
messages: Cytoplasm

8478:MFSD1
gene id: 8478:MFSD1
uniprot id: A0A8C3HZ18
names: Subcellular Location Annotation
messages: Membrane

8478:COQ10B
gene id: 8478:COQ10B
uniprot id: A0A8C3IEC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8478:CMTM8
gene id: 8478:CMTM8
uniprot id: A0A8C3IDS5
names: Subcellular Location Annotation
messages: Membrane

8478:MED21
gene id: 8478:MED21
uniprot id: A0A8C3IIJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8478:GBF1
gene id: 8478:GBF1
uniprot id: A0A8C3I5V4
names: Subcellular Location Annotation
messages: Golgi apparatus

8478:MBTPS1
gene id: 8478:MBTPS1
uniprot id: A0A8C3HDC2
names: Similarity
messages: Belongs to the peptidase S8 family.

8478:LOC101951876
gene id: 8478:LOC101951876
uniprot id: A0A8C3H6H0
names: Similarity
messages: Belongs to the HEBP family.

8478:MET
gene id: 8478:MET
uniprot id: A0A8C3H8R4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:SUSD3
gene id: 8478:SUSD3
uniprot id: A0A8C3ICQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:BRMS1
gene id: 8478:BRMS1
uniprot id: A0A8C3IFS2
names: Subcellular Location Annotation
messages: Nucleus

8478:MTRFR
gene id: 8478:MTRFR
uniprot id: A0A8C3IQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

8478:STEAP1
gene id: 8478:STEAP1
uniprot id: A0A8C3ID20
names: Subcellular Location Annotation
messages: Membrane

8478:SLC39A6
gene id: 8478:SLC39A6
uniprot id: A0A8C3F562
names: Subcellular Location Annotation
messages: Membrane

8478:DCAF10
gene id: 8478:DCAF10
uniprot id: A0A8C3FHA1
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

8478:SAP30L
gene id: 8478:SAP30L
uniprot id: A0A8C3F3U3
names: Similarity
messages: Belongs to the SAP30 family.

8478:BRINP1
gene id: 8478:BRINP1
uniprot id: A0A8C3FFH1
names: Similarity
messages: Belongs to the BRINP family.

8478:ZC3H12A
gene id: 8478:ZC3H12A
uniprot id: A0A8C3P9K4
names: Similarity
messages: Belongs to the ZC3H12 family.

8478:LOC101946049
gene id: 8478:LOC101946049
uniprot id: A0A8C3P8X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8478:TBK1
gene id: 8478:TBK1
uniprot id: A0A8C3F7X4
names: Subcellular Location Annotation
messages: Cytoplasm

8478:CENPO
gene id: 8478:CENPO
uniprot id: A0A8C3PC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

8478:PUS7L
gene id: 8478:PUS7L
uniprot id: A0A8C3HQW9
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

8478:IMMP1L
gene id: 8478:IMMP1L
uniprot id: A0A8C3HCE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

8478:EXO1
gene id: 8478:EXO1
uniprot id: A0A8C3FMR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

8478:OVOL1
gene id: 8478:OVOL1
uniprot id: A0A8C3IFE3
names: Subcellular Location Annotation
messages: Nucleus

8478:MRPS15
gene id: 8478:MRPS15
uniprot id: A0A8C3I163
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

8478:CUL1
gene id: 8478:CUL1
uniprot id: A0A8C3P8C2
names: Similarity
messages: Belongs to the cullin family.

8478:LOC101936674
gene id: 8478:LOC101936674
uniprot id: A0A8C3F8D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

8478:SLC25A5
gene id: 8478:SLC25A5
uniprot id: A0A8C3I6I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

8478:TFCP2
gene id: 8478:TFCP2
uniprot id: A0A8C3P9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

8478:GLB1
gene id: 8478:GLB1
uniprot id: A0A8C3F340
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

8478:WASHC3
gene id: 8478:WASHC3
uniprot id: A0A8C3F8C8
names: Similarity
messages: Belongs to the CCDC53 family.

8478:PSEN2
gene id: 8478:PSEN2
uniprot id: A0A8C3HCX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

8478:SPI1
gene id: 8478:SPI1
uniprot id: A0A8C3IE84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8478:PPTC7
gene id: 8478:PPTC7
uniprot id: A0A8C3F6W7
names: Similarity
messages: Belongs to the PP2C family.

8478:MTMR8
gene id: 8478:MTMR8
uniprot id: A0A8C3FBV7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8478:GLRA3
gene id: 8478:GLRA3
uniprot id: A0A8C3IK46
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8478:SLC2A13
gene id: 8478:SLC2A13
uniprot id: A0A8C3FUX1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8478:LOC101942537
gene id: 8478:LOC101942537
uniprot id: A0A8C3IS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

8478:GNG10
gene id: 8478:GNG10
uniprot id: A0A8C3FRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8478:SH3BGRL
gene id: 8478:SH3BGRL
uniprot id: A0A8C3HLG1
names: Similarity
messages: Belongs to the SH3BGR family.

8478:LOC101938302
gene id: 8478:LOC101938302
uniprot id: A0A8C3FQM5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8478:LOC101950060
gene id: 8478:LOC101950060
uniprot id: A0A8C3FF27
uniprot id: A0A8C3FKN2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8478:LARS1
gene id: 8478:LARS1
uniprot id: A0A8C3FMS0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8478:LOC101942922
gene id: 8478:LOC101942922
uniprot id: A0A8C3FXL3
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8478:CAPZB
gene id: 8478:CAPZB
uniprot id: A0A8C3IGV5
uniprot id: A0A8C3IHK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

8478:PBX3
gene id: 8478:PBX3
uniprot id: A0A8C3IZE3
uniprot id: A0A8C3J109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8478:RSBN1
gene id: 8478:RSBN1
uniprot id: A0A8C3P7I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

8478:SERINC1
gene id: 8478:SERINC1
uniprot id: A0A8C3P9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8478:AK4
gene id: 8478:AK4
uniprot id: A0A8C3F2T2
uniprot id: A0A8C3F3Z6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

8478:SH2B3
gene id: 8478:SH2B3
uniprot id: A0A8C3FC83
names: Similarity
messages: Belongs to the SH2B adapter family.

8478:LOC101945074
gene id: 8478:LOC101945074
uniprot id: A0A8C3IZL6
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8478:LOC101935267
gene id: 8478:LOC101935267
uniprot id: A0A8C3F709
names: Similarity
messages: Belongs to the multicopper oxidase family.

8478:STK38L
gene id: 8478:STK38L
uniprot id: A0A8C3IFV3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:NOTCH1
gene id: 8478:NOTCH1
uniprot id: A0A8C3HE14
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

8478:GPR137B
gene id: 8478:GPR137B
uniprot id: A0A8C3FCV3
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8478:TPRA1
gene id: 8478:TPRA1
uniprot id: A0A8C3HLR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

8478:SYNPR
gene id: 8478:SYNPR
uniprot id: A0A8C3ITS3
uniprot id: A0A8C3IU75
uniprot id: A0A8C3PFG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8478:DBX2
gene id: 8478:DBX2
uniprot id: A0A8C3HPU9
names: Subcellular Location Annotation
messages: Nucleus

8478:LOC101932458
gene id: 8478:LOC101932458
uniprot id: A0A8C3FLN7
names: Subcellular Location Annotation
messages: Membrane

8478:TARS3
gene id: 8478:TARS3
uniprot id: A0A8C3FV87
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

8478:ZRANB2
gene id: 8478:ZRANB2
uniprot id: A0A8C3PCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: May interfere with constitutive 5'-splice site selection.
messages: Nucleus

8478:GPR89B
gene id: 8478:GPR89B
uniprot id: A0A8C3FEV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

8478:TRAPPC3
gene id: 8478:TRAPPC3
uniprot id: A0A8C3HZT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

8478:TBX19
gene id: 8478:TBX19
uniprot id: A0A8C3F9Q1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8478:LOC101945756
gene id: 8478:LOC101945756
uniprot id: A0A8C3I5F7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

8478:LOC101937225
gene id: 8478:LOC101937225
uniprot id: A0A8C3HER5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8478:ALX4
gene id: 8478:ALX4
uniprot id: A0A8C3HF54
names: Subcellular Location Annotation
messages: Nucleus

8478:SLC9A5
gene id: 8478:SLC9A5
uniprot id: A0A8C3HMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

8478:FGFR1OP2
gene id: 8478:FGFR1OP2
uniprot id: A0A8C3IHF4
names: Similarity
messages: Belongs to the SIKE family.

8478:CLNS1A
gene id: 8478:CLNS1A
uniprot id: A0A8C3IXY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

8478:ALKBH5
gene id: 8478:ALKBH5
uniprot id: A0A8C3I8S6
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus speckle

8478:NTS
gene id: 8478:NTS
uniprot id: A0A8C3EYL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

8478:AGPAT5
gene id: 8478:AGPAT5
uniprot id: A0A8C3IBI8
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8478:LOC101952198
gene id: 8478:LOC101952198
uniprot id: A0A8C3HVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

8478:HOXA6
gene id: 8478:HOXA6
uniprot id: A0A8C3PCA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8478:TOP3A
gene id: 8478:TOP3A
uniprot id: A0A8C3I7G7
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

8478:TXNRD3
gene id: 8478:TXNRD3
uniprot id: A0A8C3HLA8
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

8478:SLC25A27
gene id: 8478:SLC25A27
uniprot id: A0A8C3IA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8478:TMEM200C
gene id: 8478:TMEM200C
uniprot id: A0A8C3FGU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

8478:PRICKLE1
gene id: 8478:PRICKLE1
uniprot id: A0A8C3HQH0
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8478:CUL2
gene id: 8478:CUL2
uniprot id: A0A8C3HUU2
names: Similarity
messages: Belongs to the cullin family.

8478:XPC
gene id: 8478:XPC
uniprot id: A0A8C3HLL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

8478:EPHA2
gene id: 8478:EPHA2
uniprot id: A0A8C3FTU7
names: Subcellular Location Annotation
messages: Membrane

8478:NDUFA5
gene id: 8478:NDUFA5
uniprot id: A0A8C3I6E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8478:CEP19
gene id: 8478:CEP19
uniprot id: A0A8C3I9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

8478:NDUFA1
gene id: 8478:NDUFA1
uniprot id: A0A8C3I916
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

8478:PSMC3
gene id: 8478:PSMC3
uniprot id: A0A8C3IEA5
names: Similarity
messages: Belongs to the AAA ATPase family.

8478:EPHA3
gene id: 8478:EPHA3
uniprot id: A0A8C3FKD4
names: Subcellular Location Annotation
messages: Membrane

8478:RPS16
gene id: 8478:RPS16
uniprot id: A0A8C3H555
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8478:IFT57
gene id: 8478:IFT57
uniprot id: A0A8C3H7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

8478:LOC101945004
gene id: 8478:LOC101945004
uniprot id: A0A8C3PBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8478:SCAMP1
gene id: 8478:SCAMP1
uniprot id: A0A8C3IA99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8478:KCNJ8
gene id: 8478:KCNJ8
uniprot id: A0A8C3FPI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8478:TMEM245
gene id: 8478:TMEM245
uniprot id: A0A8C3F5V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

8478:SENP2
gene id: 8478:SENP2
uniprot id: A0A8C3FM32
uniprot id: A0A8C3H8V7
names: Similarity
messages: Belongs to the peptidase C48 family.

8478:TMEM237
gene id: 8478:TMEM237
uniprot id: A0A8C3HC78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

8478:SLC1A2
gene id: 8478:SLC1A2
uniprot id: A0A8C3HET7
uniprot id: A0A8C3HEU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8478:FAM163B
gene id: 8478:FAM163B
uniprot id: A0A8C3IBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8478:XPO5
gene id: 8478:XPO5
uniprot id: A0A8C3INB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

8478:TSC22D2
gene id: 8478:TSC22D2
uniprot id: A0A8C3HMG1
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8478:ABCB9
gene id: 8478:ABCB9
uniprot id: A0A8C3PEU8
names: Subcellular Location Annotation
messages: Membrane

8478:PRKCZ
gene id: 8478:PRKCZ
uniprot id: A0A8C3IEQ6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8478:TSPAN9
gene id: 8478:TSPAN9
uniprot id: A0A8C3FS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:THEMIS
gene id: 8478:THEMIS
uniprot id: A0A8C3P9J1
names: Similarity
messages: Belongs to the themis family.

8478:ATP6V1E1
gene id: 8478:ATP6V1E1
uniprot id: A0A8C3J158
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

8478:PIK3C2B
gene id: 8478:PIK3C2B
uniprot id: A0A8C3F1K4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8478:KBTBD8
gene id: 8478:KBTBD8
uniprot id: A0A8C3IUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

8478:SULT6B1
gene id: 8478:SULT6B1
uniprot id: A0A8C3PD52
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8478:ATG2A
gene id: 8478:ATG2A
uniprot id: A0A8C3IHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

8478:NCK2
gene id: 8478:NCK2
uniprot id: A0A8C3FIE9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

8478:YIPF1
gene id: 8478:YIPF1
uniprot id: A0A8C3F6J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8478:AK1
gene id: 8478:AK1
uniprot id: A0A8C3ILK8
uniprot id: A0A8C3IMU8
uniprot id: A0A8C3IPZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

8478:TMEM35B
gene id: 8478:TMEM35B
uniprot id: A0A8C3I1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

8478:LOC101934764
gene id: 8478:LOC101934764
uniprot id: A0A8C3HD22
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8478:ST3GAL6
gene id: 8478:ST3GAL6
uniprot id: A0A8C3F839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8478:DRC7
gene id: 8478:DRC7
uniprot id: A0A8C3IUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC7 family.
messages: cilium axoneme
messages: flagellum
messages: flagellum axoneme

8478:ABI1
gene id: 8478:ABI1
uniprot id: A0A8C3HQX4
uniprot id: A0A8C3HR01
uniprot id: A0A8C3HRJ8
uniprot id: A0A8C3HRU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8478:LOC101946482
gene id: 8478:LOC101946482
uniprot id: A0A8C3PD30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

8478:MYCN
gene id: 8478:MYCN
uniprot id: A0A8C3P5K7
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8478:ENTPD6
gene id: 8478:ENTPD6
uniprot id: A0A8C3FWK8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8478:PRIM2
gene id: 8478:PRIM2
uniprot id: A0A8C3IG16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

8478:ACTR8
gene id: 8478:ACTR8
uniprot id: A0A8C3IA51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

8478:FLNB
gene id: 8478:FLNB
uniprot id: A0A8C3HKR3
uniprot id: A0A8C3HKU4
uniprot id: A0A8C3HLB1
names: Similarity
messages: Belongs to the filamin family.

8478:TRIM45
gene id: 8478:TRIM45
uniprot id: A0A8C3F7Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

8478:MEAF6
gene id: 8478:MEAF6
uniprot id: A0A8C3HZG1
uniprot id: A0A8C3HZG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

8478:GPRC5B
gene id: 8478:GPRC5B
uniprot id: A0A8C3P9B2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8478:SKA1
gene id: 8478:SKA1
uniprot id: A0A8C3IPQ6
names: Similarity
messages: Belongs to the SKA1 family.

8478:LOC101937461
gene id: 8478:LOC101937461
uniprot id: A0A8C3FR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:TGFBR2
gene id: 8478:TGFBR2
uniprot id: A0A8C3ID04
uniprot id: A0A8C3PCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

8478:METTL16
gene id: 8478:METTL16
uniprot id: A0A8C3F3B3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

8478:LOC101954021
gene id: 8478:LOC101954021
uniprot id: A0A8C3P888
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

8478:VPS35
gene id: 8478:VPS35
uniprot id: A0A8C3HSG3
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

8478:ALX3
gene id: 8478:ALX3
uniprot id: A0A8C3F2N8
names: Subcellular Location Annotation
messages: Nucleus

8478:P2RY2
gene id: 8478:P2RY2
uniprot id: A0A8C3HBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:LCLAT1
gene id: 8478:LCLAT1
uniprot id: A0A8C3HCN5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8478:KCNA6
gene id: 8478:KCNA6
uniprot id: A0A8C3IIZ2
names: Subcellular Location Annotation
messages: Membrane

8478:MIGA2
gene id: 8478:MIGA2
uniprot id: A0A8C3IDZ9
names: Similarity
messages: Belongs to the mitoguardin family.

8478:TMEM163
gene id: 8478:TMEM163
uniprot id: A0A8C3FTA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

8478:GPR17
gene id: 8478:GPR17
uniprot id: A0A8C3I272
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:NUP93
gene id: 8478:NUP93
uniprot id: A0A8C3HCZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

8478:TERT
gene id: 8478:TERT
uniprot id: A0A8C3P7X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

8478:DCLRE1B
gene id: 8478:DCLRE1B
uniprot id: A0A8C3HQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

8478:IRAK4
gene id: 8478:IRAK4
uniprot id: A0A8C3HQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

8478:LOC101942967
gene id: 8478:LOC101942967
uniprot id: A0A8C3P4W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:TNR
gene id: 8478:TNR
uniprot id: A0A8C3HLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

8478:GNG12
gene id: 8478:GNG12
uniprot id: A0A8C3F6V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8478:BCAS2
gene id: 8478:BCAS2
uniprot id: A0A8C3HSW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

8478:KCTD3
gene id: 8478:KCTD3
uniprot id: A0A8C3HGR1
names: Similarity
messages: Belongs to the KCTD3 family.

8478:ADGRF5
gene id: 8478:ADGRF5
uniprot id: A0A8C3IAY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

8478:LOC101943333
gene id: 8478:LOC101943333
uniprot id: A0A8C3IBU7
names: Subcellular Location Annotation
messages: Membrane

8478:HBP1
gene id: 8478:HBP1
uniprot id: A0A8C3F7N2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

8478:TAF5L
gene id: 8478:TAF5L
uniprot id: A0A8C3FEU8
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

8478:CACHD1
gene id: 8478:CACHD1
uniprot id: A0A8C3F3J5
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

8478:SKP1
gene id: 8478:SKP1
uniprot id: A0A8C3FK29
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

8478:STEEP1
gene id: 8478:STEEP1
uniprot id: A0A8C3PB27
names: Similarity
messages: Belongs to the STEEP1 family.

8478:ARPC3
gene id: 8478:ARPC3
uniprot id: A0A8C3IQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

8478:SLC16A1
gene id: 8478:SLC16A1
uniprot id: A0A8C3I243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8478:EXT2
gene id: 8478:EXT2
uniprot id: A0A8C3HEV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8478:FGF16
gene id: 8478:FGF16
uniprot id: A0A8C3HMT9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8478:ANKRD13A
gene id: 8478:ANKRD13A
uniprot id: A0A8C3I9X5
uniprot id: A0A8C3IC91
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8478:SLC2A5
gene id: 8478:SLC2A5
uniprot id: A0A8C3IBS3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8478:LOC101937351
gene id: 8478:LOC101937351
uniprot id: A0A8C3IFM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

8478:MTM1
gene id: 8478:MTM1
uniprot id: A0A8C3I775
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8478:GLUL
gene id: 8478:GLUL
uniprot id: A0A8C3HQV6
names: Similarity
messages: Belongs to the glutamine synthetase family.

8478:CACNB2
gene id: 8478:CACNB2
uniprot id: A0A8C3HNF9
uniprot id: A0A8C3HP03
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

8478:KCNK5
gene id: 8478:KCNK5
uniprot id: A0A8C3INZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8478:LOC101942193
gene id: 8478:LOC101942193
uniprot id: A0A8C3FU46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

8478:UCK2
gene id: 8478:UCK2
uniprot id: A0A8C3HMC3
names: Similarity
messages: Belongs to the uridine kinase family.

8478:TBL3
gene id: 8478:TBL3
uniprot id: A0A8C3EY85
names: Subcellular Location Annotation
messages: nucleolus

8478:MTCH2
gene id: 8478:MTCH2
uniprot id: A0A8C3HUG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8478:AHCYL1
gene id: 8478:AHCYL1
uniprot id: A0A8C3F322
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

8478:PGD
gene id: 8478:PGD
uniprot id: A0A8C3IBK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

8478:MEMO1
gene id: 8478:MEMO1
uniprot id: A0A8C3IJ97
names: Similarity
messages: Belongs to the MEMO1 family.

8478:DNAAF1
gene id: 8478:DNAAF1
uniprot id: A0A8C3HD83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
messages: cilium

8478:EXOC3
gene id: 8478:EXOC3
uniprot id: A0A8C3H5L7
names: Similarity
messages: Belongs to the SEC6 family.

8478:DRAXIN
gene id: 8478:DRAXIN
uniprot id: A0A8C3IEK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.
messages: Secreted

8478:HRH1
gene id: 8478:HRH1
uniprot id: A0A8C3EZL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:LOC101935791
gene id: 8478:LOC101935791
uniprot id: A0A8C3HLJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8478:LOC101933992
gene id: 8478:LOC101933992
uniprot id: A0A8C3IE92
names: Similarity
messages: Belongs to the TMEM178 family.

8478:NACC2
gene id: 8478:NACC2
uniprot id: A0A8C3HDH0
names: Subcellular Location Annotation
messages: Nucleus

8478:TWSG1
gene id: 8478:TWSG1
uniprot id: A0A8C3IZJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

8478:THOC7
gene id: 8478:THOC7
uniprot id: A0A8C3ITD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

8478:VLDLR
gene id: 8478:VLDLR
uniprot id: A0A8C3IME8
uniprot id: A0A8C3PEC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:CAMKK2
gene id: 8478:CAMKK2
uniprot id: A0A8C3IT54
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:ARMC1
gene id: 8478:ARMC1
uniprot id: A0A8C3I9B7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8478:NPL
gene id: 8478:NPL
uniprot id: A0A8C3HRI3
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

8478:SLC29A2
gene id: 8478:SLC29A2
uniprot id: A0A8C3IGM3
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

8478:ACBD5
gene id: 8478:ACBD5
uniprot id: A0A8C3P7T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane

8478:PDCD10
gene id: 8478:PDCD10
uniprot id: A0A8C3HRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8478:LOC101937707
gene id: 8478:LOC101937707
uniprot id: A0A8C3HSS4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

8478:B4GALNT1
gene id: 8478:B4GALNT1
uniprot id: A0A8C3P977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:RAB39A
gene id: 8478:RAB39A
uniprot id: A0A8C3HZS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8478:HUS1
gene id: 8478:HUS1
uniprot id: A0A8C3HVB0
names: Similarity
messages: Belongs to the HUS1 family.

8478:ADA2
gene id: 8478:ADA2
uniprot id: A0A8C3J2Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

8478:CCR4
gene id: 8478:CCR4
uniprot id: A0A8C3F0J3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:LOC101951042
gene id: 8478:LOC101951042
uniprot id: A0A8C3IA02
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:DNAJC16
gene id: 8478:DNAJC16
uniprot id: A0A8C3IJI4
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays an important role in regulating the size of autophagosomes during the formation process.

8478:TENT5C
gene id: 8478:TENT5C
uniprot id: A0A8C3F252
names: Similarity
messages: Belongs to the TENT family.

8478:PLD5
gene id: 8478:PLD5
uniprot id: A0A8C3FNX2
uniprot id: A0A8C3HA54
names: Similarity
messages: Belongs to the phospholipase D family.

8478:POLR1B
gene id: 8478:POLR1B
uniprot id: A0A8C3F8N5
uniprot id: A0A8C3FHI6
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

8478:LOC101949838
gene id: 8478:LOC101949838
uniprot id: A0A8C3F080
names: Similarity
messages: Belongs to the cystatin family.

8478:SEC61B
gene id: 8478:SEC61B
uniprot id: A0A8C3EZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

8478:EEF1G
gene id: 8478:EEF1G
uniprot id: A0A8C3HYB6
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

8478:SIDT1
gene id: 8478:SIDT1
uniprot id: A0A8C3F2Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

8478:NEK6
gene id: 8478:NEK6
uniprot id: A0A8C3PGB8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:LOC101932352
gene id: 8478:LOC101932352
uniprot id: A0A8C3HDE2
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8478:FUT11
gene id: 8478:FUT11
uniprot id: A0A8C3I7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

8478:DUSP10
gene id: 8478:DUSP10
uniprot id: A0A8C3EZB9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8478:XRN2
gene id: 8478:XRN2
uniprot id: A0A8C3IFT5
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

8478:OGT
gene id: 8478:OGT
uniprot id: A0A8C3HU85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

8478:LOC101946875
gene id: 8478:LOC101946875
uniprot id: A0A8C3FQE5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:PPM1L
gene id: 8478:PPM1L
uniprot id: A0A8C3I0G3
names: Similarity
messages: Belongs to the PP2C family.

8478:SMPDL3A
gene id: 8478:SMPDL3A
uniprot id: A0A8C3I0N0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

8478:RPL15
gene id: 8478:RPL15
uniprot id: A0A8C3IDE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Cytoplasm

8478:CZIB
gene id: 8478:CZIB
uniprot id: A0A8C3F6E6
names: Similarity
messages: Belongs to the UPF0587 family.

8478:ZDHHC5
gene id: 8478:ZDHHC5
uniprot id: A0A8C3HV31
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:LRP8
gene id: 8478:LRP8
uniprot id: A0A8C3F6H6
uniprot id: A0A8C3F6R1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:LOC101935518
gene id: 8478:LOC101935518
uniprot id: A0A8C3HL40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8478:RBM15
gene id: 8478:RBM15
uniprot id: A0A8C3F498
names: Similarity
messages: Belongs to the RRM Spen family.

8478:GCNT1
gene id: 8478:GCNT1
uniprot id: A0A8C3I3P5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8478:CAMK2A
gene id: 8478:CAMK2A
uniprot id: A0A8C3FT75
uniprot id: A0A8C3FZ26
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8478:YTHDF3
gene id: 8478:YTHDF3
uniprot id: A0A8C3I9B2
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

8478:PTPRK
gene id: 8478:PTPRK
uniprot id: A0A8C3I030
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

8478:LOC101936303
gene id: 8478:LOC101936303
uniprot id: A0A8C3EZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space
messages: Required for assembly of mitochondrial respiratory chain complexes.

8478:CCDC181
gene id: 8478:CCDC181
uniprot id: A0A8C3F7T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton

8478:TMEM218
gene id: 8478:TMEM218
uniprot id: A0A8C3FXE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

8478:DPH3
gene id: 8478:DPH3
uniprot id: A0A8C3IFH0
names: Similarity
messages: Belongs to the DPH3 family.

8478:CAPRIN2
gene id: 8478:CAPRIN2
uniprot id: A0A8C3ITT0
uniprot id: A0A8C3IV42
uniprot id: A0A8C3IXK9
names: Similarity
messages: Belongs to the caprin family.

8478:CHCHD6
gene id: 8478:CHCHD6
uniprot id: A0A8C3HLR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic25 subfamily.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Membrane
messages: Mitochondrion inner membrane

8478:LOC101950860
gene id: 8478:LOC101950860
uniprot id: A0A8C3HCL1
names: Similarity
messages: Belongs to the NLRP family.

8478:EN2
gene id: 8478:EN2
uniprot id: A0A8C3HYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

8478:HACL1
gene id: 8478:HACL1
uniprot id: A0A8C3IGH7
names: Similarity
messages: Belongs to the TPP enzyme family.

8478:WASHC1
gene id: 8478:WASHC1
uniprot id: A0A8C3IVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

8478:ADPRH
gene id: 8478:ADPRH
uniprot id: A0A8C3H838
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

8478:HOXA3
gene id: 8478:HOXA3
uniprot id: A0A8C3ID10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8478:LOC101933945
gene id: 8478:LOC101933945
uniprot id: A0A8C3HNG1
names: Similarity
messages: Belongs to the CAND family.

8478:CASD1
gene id: 8478:CASD1
uniprot id: A0A8C3IIS8
uniprot id: A0A8C3IM20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

8478:TGIF1
gene id: 8478:TGIF1
uniprot id: A0A8C3FPN3
names: Subcellular Location Annotation
messages: Nucleus

8478:EHHADH
gene id: 8478:EHHADH
uniprot id: A0A8C3FR15
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

8478:MRPL11
gene id: 8478:MRPL11
uniprot id: A0A8C3ID83
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

8478:MRPS25
gene id: 8478:MRPS25
uniprot id: A0A8C3HLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

8478:LOC101933514
gene id: 8478:LOC101933514
uniprot id: A0A8C3P9P3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:RDX
gene id: 8478:RDX
uniprot id: A0A8C3I7Z4
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8478:DYNC1LI2
gene id: 8478:DYNC1LI2
uniprot id: A0A8C3HDC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

8478:LOC101949938
gene id: 8478:LOC101949938
uniprot id: A0A8C3FRT9
names: Similarity
messages: Belongs to the COX20 family.

8478:MASP2
gene id: 8478:MASP2
uniprot id: A0A8C3IBF5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:FHIP1A
gene id: 8478:FHIP1A
uniprot id: A0A8C3IS86
names: Similarity
messages: Belongs to the FHIP family.

8478:AGK
gene id: 8478:AGK
uniprot id: A0A8C3HCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

8478:LCA5
gene id: 8478:LCA5
uniprot id: A0A8C3PCQ6
names: Similarity
messages: Belongs to the LCA5 family.

8478:NAPB
gene id: 8478:NAPB
uniprot id: A0A8C3IG37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

8478:ONECUT1
gene id: 8478:ONECUT1
uniprot id: A0A8C3IY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8478:HAGH
gene id: 8478:HAGH
uniprot id: A0A8C3I867
uniprot id: A0A8C3IBE8
uniprot id: A0A8C3PBD0
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8478:CEBPZ
gene id: 8478:CEBPZ
uniprot id: A0A8C3IH97
names: Similarity
messages: Belongs to the CBF/MAK21 family.

8478:LOC101944943
gene id: 8478:LOC101944943
uniprot id: A0A8C3IIX5
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

8478:LOC101947948
gene id: 8478:LOC101947948
uniprot id: A0A8C3IRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:OPTC
gene id: 8478:OPTC
uniprot id: A0A8C3HVV1
uniprot id: A0A8C3HY97
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

8478:SPIRE1
gene id: 8478:SPIRE1
uniprot id: A0A8C3J068
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

8478:GDAP2
gene id: 8478:GDAP2
uniprot id: A0A8C3F2W0
names: Similarity
messages: Belongs to the GDAP2 family.

8478:TAC1
gene id: 8478:TAC1
uniprot id: A0A8C3IN40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

8478:RPL35
gene id: 8478:RPL35
uniprot id: A0A8C3J0U4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

8478:EIF2D
gene id: 8478:EIF2D
uniprot id: A0A8C3H5Q2
names: Similarity
messages: Belongs to the eIF2D family.

8478:TRAM1
gene id: 8478:TRAM1
uniprot id: A0A8C3FMC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

8478:GRIN3A
gene id: 8478:GRIN3A
uniprot id: A0A8C3FS31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8478:SLC25A18
gene id: 8478:SLC25A18
uniprot id: A0A8C3IZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8478:IRAK1BP1
gene id: 8478:IRAK1BP1
uniprot id: A0A8C3IHJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

8478:LOC101945052
gene id: 8478:LOC101945052
uniprot id: A0A8C3FFG2
names: Similarity
messages: Belongs to the NXPE family.

8478:CASR
gene id: 8478:CASR
uniprot id: A0A8C3F0I1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8478:AMOTL2
gene id: 8478:AMOTL2
uniprot id: A0A8C3H571
names: Similarity
messages: Belongs to the angiomotin family.

8478:AJAP1
gene id: 8478:AJAP1
uniprot id: A0A8C3I2P8
names: Subcellular Location Annotation
messages: Membrane

8478:PEMT
gene id: 8478:PEMT
uniprot id: A0A8C3PB89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

8478:SLCO5A1
gene id: 8478:SLCO5A1
uniprot id: A0A8C3FHH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:ARPC5
gene id: 8478:ARPC5
uniprot id: A0A8C3HS73
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

8478:FAM126B
gene id: 8478:FAM126B
uniprot id: A0A8C3HCC2
uniprot id: A0A8C3P2B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8478:LOC101930993
gene id: 8478:LOC101930993
uniprot id: A0A8C3ICQ0
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse

8478:EHD3
gene id: 8478:EHD3
uniprot id: A0A8C3HCS4
uniprot id: A0A8C3P2M1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8478:BROX
gene id: 8478:BROX
uniprot id: A0A8C3HEK3
names: Similarity
messages: Belongs to the BROX family.

8478:CNTN2
gene id: 8478:CNTN2
uniprot id: A0A8C3F174
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

8478:VGLL1
gene id: 8478:VGLL1
uniprot id: A0A8C3IR10
uniprot id: A0A8C3ITC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

8478:GNPDA1
gene id: 8478:GNPDA1
uniprot id: A0A8C3HTV6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

8478:ARSI
gene id: 8478:ARSI
uniprot id: A0A8C3FT83
names: Similarity
messages: Belongs to the sulfatase family.

8478:FBLN1
gene id: 8478:FBLN1
uniprot id: A0A8C3IJ27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8478:DYRK4
gene id: 8478:DYRK4
uniprot id: A0A8C3FRZ2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8478:NMBR
gene id: 8478:NMBR
uniprot id: A0A8C3HWE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:CFAP91
gene id: 8478:CFAP91
uniprot id: A0A8C3F5N5
names: Similarity
messages: Belongs to the CFAP91 family.

8478:CAPN2
gene id: 8478:CAPN2
uniprot id: A0A8C3HED9
names: Similarity
messages: Belongs to the peptidase C2 family.

8478:CDKN1A
gene id: 8478:CDKN1A
uniprot id: A0A8C3INM2
names: Similarity
messages: Belongs to the CDI family.

8478:SQSTM1
gene id: 8478:SQSTM1
uniprot id: A0A8C3FRQ8
names: Subcellular Location Annotation
messages: autophagosome

8478:EIF4E3
gene id: 8478:EIF4E3
uniprot id: A0A8C3FFG9
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8478:GNS
gene id: 8478:GNS
uniprot id: A0A8C3F1D9
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8478:MAEL
gene id: 8478:MAEL
uniprot id: A0A8C3H8G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

8478:HIGD1A
gene id: 8478:HIGD1A
uniprot id: A0A8C3H6V6
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

8478:DCP1A
gene id: 8478:DCP1A
uniprot id: A0A8C3ICM7
names: Similarity
messages: Belongs to the DCP1 family.

8478:MBOAT2
gene id: 8478:MBOAT2
uniprot id: A0A8C3P6L7
names: Subcellular Location Annotation
messages: Membrane

8478:RSAD2
gene id: 8478:RSAD2
uniprot id: A0A8C3HKE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RSAD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:SULT4A1
gene id: 8478:SULT4A1
uniprot id: A0A8C3IMU2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8478:GALNT10
gene id: 8478:GALNT10
uniprot id: A0A8C3FB64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8478:NKIRAS1
gene id: 8478:NKIRAS1
uniprot id: A0A8C3IDD1
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

8478:HSPA4
gene id: 8478:HSPA4
uniprot id: A0A8C3HU95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

8478:VEGFA
gene id: 8478:VEGFA
uniprot id: A0A8C3IQB8
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8478:CNIH3
gene id: 8478:CNIH3
uniprot id: A0A8C3HDB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8478:ATG16L1
gene id: 8478:ATG16L1
uniprot id: A0A8C3IMV0
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

8478:RPS7
gene id: 8478:RPS7
uniprot id: A0A8C3IAT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

8478:B3GAT1
gene id: 8478:B3GAT1
uniprot id: A0A8C3HX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:HTATSF1
gene id: 8478:HTATSF1
uniprot id: A0A8C3IPK0
names: Similarity
messages: Belongs to the HTATSF1 family.

8478:CPEB1
gene id: 8478:CPEB1
uniprot id: A0A8C3FKD3
names: Similarity
messages: Belongs to the RRM CPEB family.

8478:MXRA8
gene id: 8478:MXRA8
uniprot id: A0A8C3IF39
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8478:TSHZ3
gene id: 8478:TSHZ3
uniprot id: A0A8C3HS31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8478:THUMPD3
gene id: 8478:THUMPD3
uniprot id: A0A8C3HNM0
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8478:PELI3
gene id: 8478:PELI3
uniprot id: A0A8C3ID95
names: Similarity
messages: Belongs to the pellino family.

8478:POT1
gene id: 8478:POT1
uniprot id: A0A8C3IAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

8478:TMEM63B
gene id: 8478:TMEM63B
uniprot id: A0A8C3IML7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

8478:LOC101953971
gene id: 8478:LOC101953971
uniprot id: A0A8C3HVV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

8478:CAVIN4
gene id: 8478:CAVIN4
uniprot id: A0A8C3F746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8478:PRKAB2
gene id: 8478:PRKAB2
uniprot id: A0A8C3H6U8
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

8478:SEC23B
gene id: 8478:SEC23B
uniprot id: A0A8C3IGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8478:KPNA4
gene id: 8478:KPNA4
uniprot id: A0A8C3HYV6
names: Similarity
messages: Belongs to the importin alpha family.

8478:LPIN1
gene id: 8478:LPIN1
uniprot id: A0A8C3HJZ2
uniprot id: A0A8C3HJZ3
names: Similarity
messages: Belongs to the lipin family.

8478:DCTN5
gene id: 8478:DCTN5
uniprot id: A0A8C3F8A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

8478:TSPAN31
gene id: 8478:TSPAN31
uniprot id: A0A8C3HY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:DNAAF4
gene id: 8478:DNAAF4
uniprot id: A0A8C3F9V8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

8478:PSPC1
gene id: 8478:PSPC1
uniprot id: A0A8C3PB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PSPC family.
messages: Cytoplasm
messages: Nucleus matrix
messages: Nucleus speckle
messages: nucleolus

8478:ATL3
gene id: 8478:ATL3
uniprot id: A0A8C3IJ39
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8478:ATP6V0A4
gene id: 8478:ATP6V0A4
uniprot id: A0A8C3HHT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8478:FAM72A
gene id: 8478:FAM72A
uniprot id: A0A8C3F2Q6
names: Similarity
messages: Belongs to the FAM72 family.

8478:ACTA1
gene id: 8478:ACTA1
uniprot id: A0A8C3FFU4
names: Similarity
messages: Belongs to the actin family.

8478:KIF1B
gene id: 8478:KIF1B
uniprot id: A0A8C3IBE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

8478:NSUN6
gene id: 8478:NSUN6
uniprot id: A0A8C3P797
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8478:DYRK3
gene id: 8478:DYRK3
uniprot id: A0A8C3F2R8
uniprot id: A0A8C3F443
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8478:KCNMB1
gene id: 8478:KCNMB1
uniprot id: A0A8C3II96
names: Subcellular Location Annotation
messages: Membrane

8478:MAP3K8
gene id: 8478:MAP3K8
uniprot id: A0A8C3HR15
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8478:MRPL32
gene id: 8478:MRPL32
uniprot id: A0A8C3INH9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

8478:YIPF5
gene id: 8478:YIPF5
uniprot id: A0A8C3HTJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

8478:AP4B1
gene id: 8478:AP4B1
uniprot id: A0A8C3P7I5
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8478:LBH
gene id: 8478:LBH
uniprot id: A0A8C3HCL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus

8478:NOC4L
gene id: 8478:NOC4L
uniprot id: A0A8C3IP04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Nucleus membrane

8478:NRXN2
gene id: 8478:NRXN2
uniprot id: A0A8C3II27
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:TMBIM4
gene id: 8478:TMBIM4
uniprot id: A0A8C3IKF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8478:TTC4
gene id: 8478:TTC4
uniprot id: A0A8C3H6M9
names: Similarity
messages: Belongs to the TTC4 family.

8478:AQP1
gene id: 8478:AQP1
uniprot id: A0A8C3FDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8478:USP30
gene id: 8478:USP30
uniprot id: A0A8C3FHE1
names: Similarity
messages: Belongs to the peptidase C19 family.

8478:LOC101941250
gene id: 8478:LOC101941250
uniprot id: A0A8C3IK42
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8478:DDX18
gene id: 8478:DDX18
uniprot id: A0A8C3FTR9
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8478:TAF6L
gene id: 8478:TAF6L
uniprot id: A0A8C3HY50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8478:POU3F4
gene id: 8478:POU3F4
uniprot id: A0A8C3HM07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8478:ARHGAP26
gene id: 8478:ARHGAP26
uniprot id: A0A8C3HTH2
uniprot id: A0A8C3HUG3
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

8478:GPC3
gene id: 8478:GPC3
uniprot id: A0A8C3IQC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8478:NXPH1
gene id: 8478:NXPH1
uniprot id: A0A8C3IJH3
uniprot id: A0A8C3IJJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8478:NFASC
gene id: 8478:NFASC
uniprot id: A0A8C3F658
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

8478:GNG3
gene id: 8478:GNG3
uniprot id: A0A8C3P958
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8478:WDR35
gene id: 8478:WDR35
uniprot id: A0A8C3PAJ8
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

8478:LOC101947474
gene id: 8478:LOC101947474
uniprot id: A0A8C3HM39
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:MMP17
gene id: 8478:MMP17
uniprot id: A0A8C3IL70
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8478:GNA12
gene id: 8478:GNA12
uniprot id: A0A8C3I7V4
uniprot id: A0A8C3I971
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

8478:API5
gene id: 8478:API5
uniprot id: A0A8C3HF00
names: Similarity
messages: Belongs to the API5 family.

8478:FAM20C
gene id: 8478:FAM20C
uniprot id: A0A8C3I699
names: Similarity
messages: Belongs to the FAM20 family.

8478:LOC101937286
gene id: 8478:LOC101937286
uniprot id: A0A8C3HU82
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8478:USP49
gene id: 8478:USP49
uniprot id: A0A8C3P8U6
names: Similarity
messages: Belongs to the peptidase C19 family.

8478:TEX10
gene id: 8478:TEX10
uniprot id: A0A8C3EZK5
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

8478:CPSF4
gene id: 8478:CPSF4
uniprot id: A0A8C3IAM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

8478:SLC7A6
gene id: 8478:SLC7A6
uniprot id: A0A8C3HDE7
names: Subcellular Location Annotation
messages: Membrane

8478:LOC101931242
gene id: 8478:LOC101931242
uniprot id: A0A8C3F9G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8478:LOC101937190
gene id: 8478:LOC101937190
uniprot id: A0A8C3FYA8
names: Similarity
messages: Belongs to the strictosidine synthase family.

8478:SNX20
gene id: 8478:SNX20
uniprot id: A0A8C3HRY4
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

8478:LHX3
gene id: 8478:LHX3
uniprot id: A0A8C3P3C1
names: Subcellular Location Annotation
messages: Nucleus

8478:TPST2
gene id: 8478:TPST2
uniprot id: A0A8C3I9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

8478:SMAD2
gene id: 8478:SMAD2
uniprot id: A0A8C3IN54
uniprot id: A0A8C3IP60
uniprot id: A0A8C3IPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8478:MED20
gene id: 8478:MED20
uniprot id: A0A8C3HW30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8478:STK40
gene id: 8478:STK40
uniprot id: A0A8C3I154
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

8478:LOC101935329
gene id: 8478:LOC101935329
uniprot id: A0A8C3H9B1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8478:LPCAT2
gene id: 8478:LPCAT2
uniprot id: A0A8C3P3D6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8478:ATP6V1C2
gene id: 8478:ATP6V1C2
uniprot id: A0A8C3HKF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

8478:MRPL3
gene id: 8478:MRPL3
uniprot id: A0A8C3IHJ1
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

8478:LOC101951875
gene id: 8478:LOC101951875
uniprot id: A0A8C3IEM6
names: Subcellular Location Annotation
messages: Membrane

8478:PYGM
gene id: 8478:PYGM
uniprot id: A0A8C3IKU8
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

8478:SLC26A2
gene id: 8478:SLC26A2
uniprot id: A0A8C3FK20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter which mediates sulfate uptake into chondrocytes in order to maintain adequate sulfation of proteoglycans which is needed for cartilage development. Mediates electroneutral anion exchange of sulfate ions for oxalate ions, sulfate and oxalate ions for chloride and/or hydroxyl ions and chloride ions for bromide, iodide and nitrate ions. The coupling of sulfate transport to both hydroxyl and chloride ions likely serves to ensure transport at both acidic pH when most sulfate uptake is mediated by sulfate-hydroxide exchange and alkaline pH when most sulfate uptake is mediated by sulfate-chloride exchange. Essential for chondrocyte proliferation, differentiation and cell size expansion.

8478:TMEM70
gene id: 8478:TMEM70
uniprot id: A0A8C3FI19
names: Similarity
messages: Belongs to the TMEM70 family.

8478:TMEM30A
gene id: 8478:TMEM30A
uniprot id: A0A8C3IIA8
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8478:TMEM132C
gene id: 8478:TMEM132C
uniprot id: A0A8C3IPY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8478:CAPN1
gene id: 8478:CAPN1
uniprot id: A0A8C3IH21
names: Similarity
messages: Belongs to the peptidase C2 family.

8478:LOC101945657
gene id: 8478:LOC101945657
uniprot id: A0A8C3FY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:MOSPD1
gene id: 8478:MOSPD1
uniprot id: A0A8C3IR63
names: Subcellular Location Annotation
messages: Membrane

8478:TFEB
gene id: 8478:TFEB
uniprot id: A0A8C3HVX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8478:PTH1R
gene id: 8478:PTH1R
uniprot id: A0A8C3H5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8478:PHYKPL
gene id: 8478:PHYKPL
uniprot id: A0A8C3FP53
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

8478:LOC101938305
gene id: 8478:LOC101938305
uniprot id: A0A8C3IHK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8478:ADHFE1
gene id: 8478:ADHFE1
uniprot id: A0A8C3I999
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

8478:LAMTOR5
gene id: 8478:LAMTOR5
uniprot id: A0A8C3F4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

8478:SZRD1
gene id: 8478:SZRD1
uniprot id: A0A8C3HAX8
names: Similarity
messages: Belongs to the SZRD1 family.

8478:C1GALT1
gene id: 8478:C1GALT1
uniprot id: A0A8C3PDN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
messages: Membrane

8478:ADGB
gene id: 8478:ADGB
uniprot id: A0A8C3HTM8
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:CNIH4
gene id: 8478:CNIH4
uniprot id: A0A8C3P374
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8478:CHAC1
gene id: 8478:CHAC1
uniprot id: A0A8C3HIG8
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

8478:ZC3H12C
gene id: 8478:ZC3H12C
uniprot id: A0A8C3PBB6
names: Similarity
messages: Belongs to the ZC3H12 family.

8478:RAPGEF6
gene id: 8478:RAPGEF6
uniprot id: A0A8C3IMF0
uniprot id: A0A8C3PE83
names: Similarity
messages: Belongs to the RAPGEF2 family.

8478:ACTB
gene id: 8478:ACTB
uniprot id: A0A8C3I6V8
names: Similarity
messages: Belongs to the actin family.

8478:TMEM53
gene id: 8478:TMEM53
uniprot id: A0A8C3F7U9
uniprot id: A0A8C3F825
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

8478:SFXN1
gene id: 8478:SFXN1
uniprot id: A0A8C3FKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

8478:FGF18
gene id: 8478:FGF18
uniprot id: A0A8C3IAW5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8478:CBWD3
gene id: 8478:CBWD3
uniprot id: A0A8C3IN97
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

8478:LOC101936307
gene id: 8478:LOC101936307
uniprot id: A0A8C3FKL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8478:STXBP5
gene id: 8478:STXBP5
uniprot id: A0A8C3HTL9
uniprot id: A0A8C3HTN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8478:ALG6
gene id: 8478:ALG6
uniprot id: A0A8C3HL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:MUS81
gene id: 8478:MUS81
uniprot id: A0A8C3IGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

8478:POU6F1
gene id: 8478:POU6F1
uniprot id: A0A8C3I104
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8478:ALDOB
gene id: 8478:ALDOB
uniprot id: A0A8C3HA87
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

8478:ATG4C
gene id: 8478:ATG4C
uniprot id: A0A8C3HL31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8478:ABCA3
gene id: 8478:ABCA3
uniprot id: A0A8C3EZD8
names: Subcellular Location Annotation
messages: Membrane

8478:GAL3ST3
gene id: 8478:GAL3ST3
uniprot id: A0A8C3ID52
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8478:TM4SF19
gene id: 8478:TM4SF19
uniprot id: A0A8C3I988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8478:MC4R
gene id: 8478:MC4R
uniprot id: A0A8C3F4H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

8478:KCNJ5
gene id: 8478:KCNJ5
uniprot id: A0A8C3ITU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

8478:PTN
gene id: 8478:PTN
uniprot id: A0A8C3FXP8
names: Similarity
messages: Belongs to the pleiotrophin family.

8478:QPCT
gene id: 8478:QPCT
uniprot id: A0A8C3IH87
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

8478:ZPR1
gene id: 8478:ZPR1
uniprot id: A0A8C3I8J6
names: Similarity
messages: Belongs to the ZPR1 family.

8478:STK10
gene id: 8478:STK10
uniprot id: A0A8C3FJE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cell membrane

8478:CBLB
gene id: 8478:CBLB
uniprot id: A0A8C3FAD4
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

8478:PDLIM1
gene id: 8478:PDLIM1
uniprot id: A0A8C3PEJ7
names: Subcellular Location Annotation
messages: Z line

8478:ANXA1
gene id: 8478:ANXA1
uniprot id: A0A8C3I4V9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium

8478:LOC101954012
gene id: 8478:LOC101954012
uniprot id: A0A8C3FPL3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8478:LOC101948875
gene id: 8478:LOC101948875
uniprot id: A0A8C3HP57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

8478:DENND6A
gene id: 8478:DENND6A
uniprot id: A0A8C3HE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

8478:CITED2
gene id: 8478:CITED2
uniprot id: A0A8C3HVH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

8478:TNFSF10
gene id: 8478:TNFSF10
uniprot id: A0A8C3HR39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8478:CD28
gene id: 8478:CD28
uniprot id: A0A8C3FVD8
names: Subcellular Location Annotation
messages: Membrane

8478:TUBB6
gene id: 8478:TUBB6
uniprot id: A0A8C3IZ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8478:MYBL1
gene id: 8478:MYBL1
uniprot id: A0A8C3I922
names: Subcellular Location Annotation
messages: Nucleus

8478:HNRNPAB
gene id: 8478:HNRNPAB
uniprot id: A0A8C3FNW3
uniprot id: A0A8C3H9S6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8478:MRPL44
gene id: 8478:MRPL44
uniprot id: A0A8C3I5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

8478:CSF1R
gene id: 8478:CSF1R
uniprot id: A0A8C3FVQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8478:LOC101941771
gene id: 8478:LOC101941771
uniprot id: A0A8C3I1S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

8478:CREB5
gene id: 8478:CREB5
uniprot id: A0A8C3IFJ5
uniprot id: A0A8C3PCA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.
messages: Binds to the cAMP response element and activates transcription.
messages: Nucleus

8478:MTHFR
gene id: 8478:MTHFR
uniprot id: A0A8C3IEK2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

8478:LOC101953520
gene id: 8478:LOC101953520
uniprot id: A0A8C3HWD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:NSG2
gene id: 8478:NSG2
uniprot id: A0A8C3H8Y7
names: Similarity
messages: Belongs to the NSG family.

8478:ACAD10
gene id: 8478:ACAD10
uniprot id: A0A8C3F918
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8478:ETV7
gene id: 8478:ETV7
uniprot id: A0A8C3IQG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8478:LOC101946313
gene id: 8478:LOC101946313
uniprot id: A0A8C3IFW0
uniprot id: A0A8C3IGB8
uniprot id: A0A8C3IGS1
names: Subcellular Location Annotation
messages: Membrane

8478:LOC101951236
gene id: 8478:LOC101951236
uniprot id: A0A8C3IC84
names: Subcellular Location Annotation
messages: Nucleus

8478:LOC101946342
gene id: 8478:LOC101946342
uniprot id: A0A8C3HXK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8478:ETF1
gene id: 8478:ETF1
uniprot id: A0A8C3I9F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

8478:RPN1
gene id: 8478:RPN1
uniprot id: A0A8C3HL49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8478:HTR4
gene id: 8478:HTR4
uniprot id: A0A8C3FSK9
uniprot id: A0A8C3H9L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

8478:SLC4A7
gene id: 8478:SLC4A7
uniprot id: A0A8C3IDJ7
uniprot id: A0A8C3IDK7
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

8478:MPHOSPH10
gene id: 8478:MPHOSPH10
uniprot id: A0A8C3FY80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

8478:ACAA2
gene id: 8478:ACAA2
uniprot id: A0A8C3PEG8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8478:PDK4
gene id: 8478:PDK4
uniprot id: A0A8C3PDN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8478:GDA
gene id: 8478:GDA
uniprot id: A0A8C3I5Q3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

8478:HSPB2
gene id: 8478:HSPB2
uniprot id: A0A8C3FWB6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8478:INO80
gene id: 8478:INO80
uniprot id: A0A8C3HIQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

8478:NUDT7
gene id: 8478:NUDT7
uniprot id: A0A8C3FXU5
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

8478:GADL1
gene id: 8478:GADL1
uniprot id: A0A8C3IDN3
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8478:ASTE1
gene id: 8478:ASTE1
uniprot id: A0A8C3IDD2
names: Similarity
messages: Belongs to the asteroid family.

8478:ACTN3
gene id: 8478:ACTN3
uniprot id: A0A8C3IIC3
names: Similarity
messages: Belongs to the alpha-actinin family.

8478:FOXC2
gene id: 8478:FOXC2
uniprot id: A0A8C3IJC6
names: Subcellular Location Annotation
messages: Nucleus

8478:LOC101953804
gene id: 8478:LOC101953804
uniprot id: A0A8C3HU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:COL4A6
gene id: 8478:COL4A6
uniprot id: A0A8C3F3C4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

8478:STYXL2
gene id: 8478:STYXL2
uniprot id: A0A8C3FEE9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8478:GTPBP8
gene id: 8478:GTPBP8
uniprot id: A0A8C3H6W5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

8478:SLC20A1
gene id: 8478:SLC20A1
uniprot id: A0A8C3IN06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

8478:REXO4
gene id: 8478:REXO4
uniprot id: A0A8C3I8E5
names: Similarity
messages: Belongs to the REXO4 family.

8478:LOC101946465
gene id: 8478:LOC101946465
uniprot id: A0A8C3HXP1
names: Similarity
messages: Belongs to the phospholipase D family.

8478:PDE7B
gene id: 8478:PDE7B
uniprot id: A0A8C3HWQ9
uniprot id: A0A8C3HXU5
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8478:CLDN11
gene id: 8478:CLDN11
uniprot id: A0A8C3HTB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8478:BCL2L13
gene id: 8478:BCL2L13
uniprot id: A0A8C3IYZ1
names: Similarity
messages: Belongs to the Bcl-2 family.

8478:NXT2
gene id: 8478:NXT2
uniprot id: A0A8C3F056
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

8478:PDGFA
gene id: 8478:PDGFA
uniprot id: A0A8C3I6B6
uniprot id: A0A8C3I711
uniprot id: A0A8C3PAY0
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8478:NAV2
gene id: 8478:NAV2
uniprot id: A0A8C3HK45
names: Similarity
messages: Belongs to the Nav/unc-53 family.

8478:WIF1
gene id: 8478:WIF1
uniprot id: A0A8C3F1I2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8478:TTC39B
gene id: 8478:TTC39B
uniprot id: A0A8C3IN13
uniprot id: A0A8C3INS2
names: Similarity
messages: Belongs to the TTC39 family.

8478:ADCY9
gene id: 8478:ADCY9
uniprot id: A0A8C3IRY3
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

8478:ERN2
gene id: 8478:ERN2
uniprot id: A0A8C3F3F0
names: Subcellular Location Annotation
messages: Membrane

8478:RAB39B
gene id: 8478:RAB39B
uniprot id: A0A8C3H586
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8478:MED9
gene id: 8478:MED9
uniprot id: A0A8C3I9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8478:TP73
gene id: 8478:TP73
uniprot id: A0A8C3I2N3
uniprot id: A0A8C3I3E4
uniprot id: A0A8C3PA74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Found in a complex with p53/TP53 and CABLES1.
messages: Nucleus
messages: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

8478:IGFBP1
gene id: 8478:IGFBP1
uniprot id: A0A8C3P8B1
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8478:USP10
gene id: 8478:USP10
uniprot id: A0A8C3IHP8
uniprot id: A0A8C3IJG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm

8478:SLC39A12
gene id: 8478:SLC39A12
uniprot id: A0A8C3HND7
uniprot id: A0A8C3HPS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

8478:SGSM1
gene id: 8478:SGSM1
uniprot id: A0A8C3PBP2
names: Similarity
messages: Belongs to the RUTBC family.

8478:SDF4
gene id: 8478:SDF4
uniprot id: A0A8C3IEA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

8478:PRRX1
gene id: 8478:PRRX1
uniprot id: A0A8C3P514
names: Subcellular Location Annotation
messages: Nucleus

8478:SNAP23
gene id: 8478:SNAP23
uniprot id: A0A8C3HGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

8478:LOC101931482
gene id: 8478:LOC101931482
uniprot id: A0A8C3FMH9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8478:CC2D1B
gene id: 8478:CC2D1B
uniprot id: A0A8C3HN16
names: Similarity
messages: Belongs to the CC2D1 family.

8478:ARF1
gene id: 8478:ARF1
uniprot id: A0A8C3F337
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8478:CEBPG
gene id: 8478:CEBPG
uniprot id: A0A8C3F1B4
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

8478:IL1RL1
gene id: 8478:IL1RL1
uniprot id: A0A8C3FJI2
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8478:CHD5
gene id: 8478:CHD5
uniprot id: A0A8C3I2D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8478:ATP6V1A
gene id: 8478:ATP6V1A
uniprot id: A0A8C3F1I6
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

8478:LOC101952321
gene id: 8478:LOC101952321
uniprot id: A0A8C3F736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:LOC101938211
gene id: 8478:LOC101938211
uniprot id: A0A8C3FGE2
names: Similarity
messages: Belongs to the MS4A family.

8478:SLC29A1
gene id: 8478:SLC29A1
uniprot id: A0A8C3PE86
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

8478:GINS2
gene id: 8478:GINS2
uniprot id: A0A8C3IJ49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

8478:CA8
gene id: 8478:CA8
uniprot id: A0A8C3II29
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

8478:DENR
gene id: 8478:DENR
uniprot id: A0A8C3IR70
names: Similarity
messages: Belongs to the DENR family.

8478:SLC35C1
gene id: 8478:SLC35C1
uniprot id: A0A8C3HF89
names: Subcellular Location Annotation
messages: Membrane

8478:CNEP1R1
gene id: 8478:CNEP1R1
uniprot id: A0A8C3HRG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

8478:LOC101939147
gene id: 8478:LOC101939147
uniprot id: A0A8C3HWF2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

8478:GLIS3
gene id: 8478:GLIS3
uniprot id: A0A8C3PEC6
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8478:LOC101939406
gene id: 8478:LOC101939406
uniprot id: A0A8C3P5N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8478:LOC101932119
gene id: 8478:LOC101932119
uniprot id: A0A8C3F6L3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

8478:SPARC
gene id: 8478:SPARC
uniprot id: A0A8C3FTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

8478:VGLL4
gene id: 8478:VGLL4
uniprot id: A0A8C3HU46
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8478:DVL1
gene id: 8478:DVL1
uniprot id: A0A8C3PCK1
names: Similarity
messages: Belongs to the DSH family.

8478:FOXP4
gene id: 8478:FOXP4
uniprot id: A0A8C3HX79
names: Subcellular Location Annotation
messages: Nucleus

8478:NDST1
gene id: 8478:NDST1
uniprot id: A0A8C3HAL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

8478:LOC101953089
gene id: 8478:LOC101953089
uniprot id: A0A8C3IL06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

8478:ACTL6A
gene id: 8478:ACTL6A
uniprot id: A0A8C3PFJ5
names: Similarity
messages: Belongs to the actin family.

8478:WNT16
gene id: 8478:WNT16
uniprot id: A0A8C3FM65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8478:CUX2
gene id: 8478:CUX2
uniprot id: A0A8C3F6X6
uniprot id: A0A8C3FAF1
uniprot id: A0A8C3H6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8478:GDE1
gene id: 8478:GDE1
uniprot id: A0A8C3G076
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8478:NOC2L
gene id: 8478:NOC2L
uniprot id: A0A8C3IB39
names: Similarity
messages: Belongs to the NOC2 family.

8478:TRIM71
gene id: 8478:TRIM71
uniprot id: A0A8C3IDW5
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8478:SLC7A3
gene id: 8478:SLC7A3
uniprot id: A0A8C3HUG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8478:TIGD3
gene id: 8478:TIGD3
uniprot id: A0A8C3PD60
names: Subcellular Location Annotation
messages: Nucleus

8478:AURKAIP1
gene id: 8478:AURKAIP1
uniprot id: A0A8C3PCK3
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

8478:ARPC1B
gene id: 8478:ARPC1B
uniprot id: A0A8C3PB64
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

8478:ACSS3
gene id: 8478:ACSS3
uniprot id: A0A8C3EXQ3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8478:LRP3
gene id: 8478:LRP3
uniprot id: A0A8C3F0X1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:DISP3
gene id: 8478:DISP3
uniprot id: A0A8C3IDT9
names: Subcellular Location Annotation
messages: Membrane

8478:LOC101954184
gene id: 8478:LOC101954184
uniprot id: A0A8C3IDJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8478:MECOM
gene id: 8478:MECOM
uniprot id: A0A8C3HRP2
names: Subcellular Location Annotation
messages: Nucleus

8478:CCNL1
gene id: 8478:CCNL1
uniprot id: A0A8C3HZS4
names: Similarity
messages: Belongs to the cyclin family.

8478:METTL6
gene id: 8478:METTL6
uniprot id: A0A8C3ID94
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

8478:ARHGEF9
gene id: 8478:ARHGEF9
uniprot id: A0A8C3H600
uniprot id: A0A8C3H6F2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

8478:PDE4B
gene id: 8478:PDE4B
uniprot id: A0A8C3F271
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8478:AASDHPPT
gene id: 8478:AASDHPPT
uniprot id: A0A8C3F0D4
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

8478:ROCK2
gene id: 8478:ROCK2
uniprot id: A0A8C3HK11
uniprot id: A0A8C3P6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: centrosome

8478:SLC6A6
gene id: 8478:SLC6A6
uniprot id: A0A8C3HMA6
uniprot id: A0A8C3HMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

8478:GDPD5
gene id: 8478:GDPD5
uniprot id: A0A8C3IWI5
uniprot id: A0A8C3J0R0
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8478:MRPL20
gene id: 8478:MRPL20
uniprot id: A0A8C3IHR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

8478:KCNV2
gene id: 8478:KCNV2
uniprot id: A0A8C3IQU3
names: Subcellular Location Annotation
messages: Membrane

8478:LXN
gene id: 8478:LXN
uniprot id: A0A8C3P9G1
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

8478:UBAP2
gene id: 8478:UBAP2
uniprot id: A0A8C3FDZ9
uniprot id: A0A8C3FJL0
names: Subcellular Location Annotation
messages: Cytoplasm

8478:STK32A
gene id: 8478:STK32A
uniprot id: A0A8C3P9W5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:EXOSC2
gene id: 8478:EXOSC2
uniprot id: A0A8C3IFT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

8478:ELAC1
gene id: 8478:ELAC1
uniprot id: A0A8C3IRN2
names: Subunit
messages: Homodimer.

8478:ATPAF2
gene id: 8478:ATPAF2
uniprot id: A0A8C3I8Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

8478:NINJ1
gene id: 8478:NINJ1
uniprot id: A0A8C3IDH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

8478:ERH
gene id: 8478:ERH
uniprot id: A0A8C3IAR7
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

8478:WFIKKN1
gene id: 8478:WFIKKN1
uniprot id: A0A8C3IPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Secreted

8478:FAM163A
gene id: 8478:FAM163A
uniprot id: A0A8C3ISE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8478:RPS17
gene id: 8478:RPS17
uniprot id: A0A8C3FFK7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

8478:SLC6A17
gene id: 8478:SLC6A17
uniprot id: A0A8C3F1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8478:THRB
gene id: 8478:THRB
uniprot id: A0A8C3IDF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

8478:PHACTR2
gene id: 8478:PHACTR2
uniprot id: A0A8C3HV71
uniprot id: A0A8C3HVA5
uniprot id: A0A8C3HWB8
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

8478:MMP2
gene id: 8478:MMP2
uniprot id: A0A8C3HDN2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

8478:SLC25A33
gene id: 8478:SLC25A33
uniprot id: A0A8C3IAZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8478:BSCL2
gene id: 8478:BSCL2
uniprot id: A0A8C3HXS1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:MPPE1
gene id: 8478:MPPE1
uniprot id: A0A8C3J1U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

8478:TRUB2
gene id: 8478:TRUB2
uniprot id: A0A8C3IR42
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

8478:C2H7orf25
gene id: 8478:C2H7orf25
uniprot id: A0A8C3PDZ1
names: Similarity
messages: Belongs to the UPF0415 family.

8478:KIF9
gene id: 8478:KIF9
uniprot id: A0A8C3HPC6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8478:MARS2
gene id: 8478:MARS2
uniprot id: A0A8C3HD82
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8478:GRIK3
gene id: 8478:GRIK3
uniprot id: A0A8C3I124
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8478:MRRF
gene id: 8478:MRRF
uniprot id: A0A8C3FUW7
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

8478:IMPA2
gene id: 8478:IMPA2
uniprot id: A0A8C3PGJ0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8478:TAMM41
gene id: 8478:TAMM41
uniprot id: A0A8C3EY95
uniprot id: A0A8C3F1K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

8478:MCEE
gene id: 8478:MCEE
uniprot id: A0A8C3FWX2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

8478:SPCS2
gene id: 8478:SPCS2
uniprot id: A0A8C3H553
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:BMP5
gene id: 8478:BMP5
uniprot id: A0A8C3ICG8
names: Similarity
messages: Belongs to the TGF-beta family.

8478:RNF168
gene id: 8478:RNF168
uniprot id: A0A8C3I9Z7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF168 family.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

8478:BBS2
gene id: 8478:BBS2
uniprot id: A0A8C3HD40
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

8478:TTC21A
gene id: 8478:TTC21A
uniprot id: A0A8C3HZU4
names: Similarity
messages: Belongs to the TTC21 family.

8478:RPS8
gene id: 8478:RPS8
uniprot id: A0A8C3F8Y8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

8478:BDNF
gene id: 8478:BDNF
uniprot id: A0A8C3FAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
messages: Secreted

8478:ABI2
gene id: 8478:ABI2
uniprot id: A0A8C3FP23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8478:PARD3
gene id: 8478:PARD3
uniprot id: A0A8C3HWZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

8478:NIP7
gene id: 8478:NIP7
uniprot id: A0A8C3IT49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

8478:ARPC1A
gene id: 8478:ARPC1A
uniprot id: A0A8C3I7H1
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

8478:STX6
gene id: 8478:STX6
uniprot id: A0A8C3PEP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

8478:TMEM255A
gene id: 8478:TMEM255A
uniprot id: A0A8C3PB18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

8478:LOC101951432
gene id: 8478:LOC101951432
uniprot id: A0A8C3EZM6
uniprot id: A0A8C3H529
names: Subcellular Location Annotation
messages: Cytoplasm

8478:PLCG2
gene id: 8478:PLCG2
uniprot id: A0A8C3IKM1
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

8478:ZCCHC8
gene id: 8478:ZCCHC8
uniprot id: A0A8C3F5H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

8478:LHFPL1
gene id: 8478:LHFPL1
uniprot id: A0A8C3P8M4
names: Subcellular Location Annotation
messages: Membrane

8478:AVPR1A
gene id: 8478:AVPR1A
uniprot id: A0A8C3F502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8478:SDHAF3
gene id: 8478:SDHAF3
uniprot id: A0A8C3IJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

8478:SLC15A4
gene id: 8478:SLC15A4
uniprot id: A0A8C3PE12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

8478:TSR3
gene id: 8478:TSR3
uniprot id: A0A8C3F6U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:CHST2
gene id: 8478:CHST2
uniprot id: A0A8C3HCJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8478:TRAK2
gene id: 8478:TRAK2
uniprot id: A0A8C3HC89
uniprot id: A0A8C3P274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

8478:LOC101934489
gene id: 8478:LOC101934489
uniprot id: A0A8C3HDK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

8478:LOC101933753
gene id: 8478:LOC101933753
uniprot id: A0A8C3IH09
names: Subcellular Location Annotation
messages: Membrane

8478:PEPD
gene id: 8478:PEPD
uniprot id: A0A8C3F2A2
names: Similarity
messages: Belongs to the peptidase M24B family.

8478:REN
gene id: 8478:REN
uniprot id: A0A8C3P8T5
names: Similarity
messages: Belongs to the peptidase A1 family.

8478:KCTD20
gene id: 8478:KCTD20
uniprot id: A0A8C3PE80
names: Subcellular Location Annotation
messages: Cytoplasm

8478:CHL1
gene id: 8478:CHL1
uniprot id: A0A8C3IYX1
uniprot id: A0A8C3IZ02
uniprot id: A0A8C3J1T6
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

8478:LAMB3
gene id: 8478:LAMB3
uniprot id: A0A8C3I8E6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:CNOT6
gene id: 8478:CNOT6
uniprot id: A0A8C3FPA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

8478:OXSM
gene id: 8478:OXSM
uniprot id: A0A8C3ICR6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

8478:LOC101950054
gene id: 8478:LOC101950054
uniprot id: A0A8C3IGW0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8478:HS3ST2
gene id: 8478:HS3ST2
uniprot id: A0A8C3F4X7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8478:LOC101942029
gene id: 8478:LOC101942029
uniprot id: A0A8C3I2V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

8478:DMRT1
gene id: 8478:DMRT1
uniprot id: A0A8C3IS47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8478:LOC101931671
gene id: 8478:LOC101931671
uniprot id: A0A8C3IBM4
names: Similarity
messages: Belongs to the CTNNBIP1 family.

8478:HDAC10
gene id: 8478:HDAC10
uniprot id: A0A8C3I8C4
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

8478:LOC101941396
gene id: 8478:LOC101941396
uniprot id: A0A8C3ILG2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8478:VDAC1
gene id: 8478:VDAC1
uniprot id: A0A8C3IPR3
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

8478:FZD3
gene id: 8478:FZD3
uniprot id: A0A8C3I4U7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:CHPT1
gene id: 8478:CHPT1
uniprot id: A0A8C3F843
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8478:AGPAT2
gene id: 8478:AGPAT2
uniprot id: A0A8C3HDX0
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

8478:CDT1
gene id: 8478:CDT1
uniprot id: A0A8C3PCZ0
names: Similarity
messages: Belongs to the Cdt1 family.

8478:DUSP16
gene id: 8478:DUSP16
uniprot id: A0A8C3H5C8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8478:CDK4
gene id: 8478:CDK4
uniprot id: A0A8C3P992
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:GLIS2
gene id: 8478:GLIS2
uniprot id: A0A8C3PEZ6
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8478:GABRA1
gene id: 8478:GABRA1
uniprot id: A0A8C3H9B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8478:KAT5
gene id: 8478:KAT5
uniprot id: A0A8C3IGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8478:MEOX2
gene id: 8478:MEOX2
uniprot id: A0A8C3IAW0
names: Subcellular Location Annotation
messages: Nucleus

8478:STEAP2
gene id: 8478:STEAP2
uniprot id: A0A8C3PBP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8478:USP3
gene id: 8478:USP3
uniprot id: A0A8C3HX91
names: Similarity
messages: Belongs to the peptidase C19 family.

8478:SLC6A19
gene id: 8478:SLC6A19
uniprot id: A0A8C3HSA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8478:CHDH
gene id: 8478:CHDH
uniprot id: A0A8C3PBK9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

8478:NIF3L1
gene id: 8478:NIF3L1
uniprot id: A0A8C3HCD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

8478:FIGNL1
gene id: 8478:FIGNL1
uniprot id: A0A8C3HTI8
names: Similarity
messages: Belongs to the AAA ATPase family.

8478:CDX1
gene id: 8478:CDX1
uniprot id: A0A8C3HAK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

8478:LOC101937211
gene id: 8478:LOC101937211
uniprot id: A0A8C3HUL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8478:TMEM116
gene id: 8478:TMEM116
uniprot id: A0A8C3F7T1
names: Subcellular Location Annotation
messages: Membrane

8478:MYD88
gene id: 8478:MYD88
uniprot id: A0A8C3HZA1
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm

8478:LOC101934902
gene id: 8478:LOC101934902
uniprot id: A0A8C3FQ96
names: Subcellular Location Annotation
messages: Membrane

8478:PALS1
gene id: 8478:PALS1
uniprot id: A0A8C3FKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

8478:LOC101931070
gene id: 8478:LOC101931070
uniprot id: A0A8C3FMC6
uniprot id: A0A8C3FUS6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

8478:LOC101938107
gene id: 8478:LOC101938107
uniprot id: A0A8C3IJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

8478:GPI
gene id: 8478:GPI
uniprot id: A0A8C3F534
names: Similarity
messages: Belongs to the GPI family.

8478:HOXA5
gene id: 8478:HOXA5
uniprot id: A0A8C3IFH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8478:SLC25A36
gene id: 8478:SLC25A36
uniprot id: A0A8C3I223
uniprot id: A0A8C3PA45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8478:BCO1
gene id: 8478:BCO1
uniprot id: A0A8C3IJ10
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8478:KIF26B
gene id: 8478:KIF26B
uniprot id: A0A8C3FQ64
uniprot id: A0A8C3FXN8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8478:PAIP2
gene id: 8478:PAIP2
uniprot id: A0A8C3FMG6
names: Similarity
messages: Belongs to the PAIP2 family.

8478:HLX
gene id: 8478:HLX
uniprot id: A0A8C3F0G3
names: Subcellular Location Annotation
messages: Nucleus

8478:CCDC85B
gene id: 8478:CCDC85B
uniprot id: A0A8C3IFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

8478:GRM7
gene id: 8478:GRM7
uniprot id: A0A8C3HML0
uniprot id: A0A8C3HML8
uniprot id: A0A8C3HN49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8478:PTTG1
gene id: 8478:PTTG1
uniprot id: A0A8C3FKK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

8478:POP4
gene id: 8478:POP4
uniprot id: A0A8C3HRZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

8478:ALDH8A1
gene id: 8478:ALDH8A1
uniprot id: A0A8C3HWS0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8478:C7H18orf25
gene id: 8478:C7H18orf25
uniprot id: A0A8C3IPJ4
uniprot id: A0A8C3IPP7
names: Subcellular Location Annotation
messages: Nucleus

8478:TATDN2
gene id: 8478:TATDN2
uniprot id: A0A8C3HMC1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8478:VPS4A
gene id: 8478:VPS4A
uniprot id: A0A8C3PFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8478:NGLY1
gene id: 8478:NGLY1
uniprot id: A0A8C3IDD7
uniprot id: A0A8C3IFW8
uniprot id: A0A8C3IGR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.

8478:KCNE4
gene id: 8478:KCNE4
uniprot id: A0A8C3I354
names: Similarity
messages: Belongs to the potassium channel KCNE family.

8478:CSTF2
gene id: 8478:CSTF2
uniprot id: A0A8C3HKZ1
uniprot id: A0A8C3HM25
names: Subcellular Location Annotation
messages: Nucleus

8478:ACAT1
gene id: 8478:ACAT1
uniprot id: A0A8C3I0D4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8478:GABRB2
gene id: 8478:GABRB2
uniprot id: A0A8C3FKR9
uniprot id: A0A8C3FLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8478:TCEANC2
gene id: 8478:TCEANC2
uniprot id: A0A8C3F6Y7
names: Subcellular Location Annotation
messages: Nucleus

8478:PTK2B
gene id: 8478:PTK2B
uniprot id: A0A8C3IC72
uniprot id: A0A8C3IFN9
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

8478:PLIN2
gene id: 8478:PLIN2
uniprot id: A0A8C3I107
names: Similarity
messages: Belongs to the perilipin family.

8478:GPR39
gene id: 8478:GPR39
uniprot id: A0A8C3FSN3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:LHX2
gene id: 8478:LHX2
uniprot id: A0A8C3IYL9
names: Subcellular Location Annotation
messages: Nucleus

8478:APOA4
gene id: 8478:APOA4
uniprot id: A0A8C3I6B4
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8478:TRPV4
gene id: 8478:TRPV4
uniprot id: A0A8C3IC57
names: Subcellular Location Annotation
messages: Membrane

8478:NLGN3
gene id: 8478:NLGN3
uniprot id: A0A8C3HTN9
uniprot id: A0A8C3HU76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8478:SLCO2A1
gene id: 8478:SLCO2A1
uniprot id: A0A8C3I8R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8478:NAA40
gene id: 8478:NAA40
uniprot id: A0A8C3IHA8
uniprot id: A0A8C3IHB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

8478:LOC101945150
gene id: 8478:LOC101945150
uniprot id: A0A8C3EZ49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
messages: centrosome
messages: cilium basal body

8478:EEF2K
gene id: 8478:EEF2K
uniprot id: A0A8C3I255
uniprot id: A0A8C3I2W1
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

8478:SMC4
gene id: 8478:SMC4
uniprot id: A0A8C3HZK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Chromosome
messages: Nucleus

8478:DBX1
gene id: 8478:DBX1
uniprot id: A0A8C3HKG9
names: Subcellular Location Annotation
messages: Nucleus

8478:HTR1B
gene id: 8478:HTR1B
uniprot id: A0A8C3IF35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1D.
messages: Membrane

8478:HSPB7
gene id: 8478:HSPB7
uniprot id: A0A8C3HBB9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8478:LRRC42
gene id: 8478:LRRC42
uniprot id: A0A8C3F6V6
names: Similarity
messages: Belongs to the LRRC42 family.

8478:LOC101930942
gene id: 8478:LOC101930942
uniprot id: A0A8C3HUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

8478:KATNA1
gene id: 8478:KATNA1
uniprot id: A0A8C3HTG6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

8478:CSNK1G1
gene id: 8478:CSNK1G1
uniprot id: A0A8C3FEP5
uniprot id: A0A8C3H826
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

8478:AGO3
gene id: 8478:AGO3
uniprot id: A0A8C3HZU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

8478:SMG7
gene id: 8478:SMG7
uniprot id: A0A8C3HQI4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

8478:LOC101934695
gene id: 8478:LOC101934695
uniprot id: A0A8C3INF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8478:GPSM1
gene id: 8478:GPSM1
uniprot id: A0A8C3HDL9
uniprot id: A0A8C3HDP9
uniprot id: A0A8C3P3B5
names: Similarity
messages: Belongs to the GPSM family.

8478:STRADB
gene id: 8478:STRADB
uniprot id: A0A8C3HC83
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

8478:YAF2
gene id: 8478:YAF2
uniprot id: A0A8C3HPS2
names: Subcellular Location Annotation
messages: Nucleus

8478:ACER2
gene id: 8478:ACER2
uniprot id: A0A8C3I0Z0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:BTD
gene id: 8478:BTD
uniprot id: A0A8C3ID15
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

8478:GSN
gene id: 8478:GSN
uniprot id: A0A8C3FTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
messages: cytoskeleton

8478:NMNAT3
gene id: 8478:NMNAT3
uniprot id: A0A8C3I525
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

8478:PLPPR1
gene id: 8478:PLPPR1
uniprot id: A0A8C3FRP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8478:TPD52L1
gene id: 8478:TPD52L1
uniprot id: A0A8C3HZN4
uniprot id: A0A8C3HZN7
uniprot id: A0A8C3I2E6
names: Similarity
messages: Belongs to the TPD52 family.

8478:FTO
gene id: 8478:FTO
uniprot id: A0A8C3HDN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

8478:BNIP1
gene id: 8478:BNIP1
uniprot id: A0A8C3FPC7
names: Subcellular Location Annotation
messages: Membrane

8478:ID2
gene id: 8478:ID2
uniprot id: A0A8C3P6N4
names: Subcellular Location Annotation
messages: Nucleus

8478:ATP5PB
gene id: 8478:ATP5PB
uniprot id: A0A8C3I9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

8478:SWI5
gene id: 8478:SWI5
uniprot id: A0A8C3IMQ1
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

8478:BET1
gene id: 8478:BET1
uniprot id: A0A8C3INP6
names: Subcellular Location Annotation
messages: Membrane

8478:IMP3
gene id: 8478:IMP3
uniprot id: A0A8C3I9K7
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

8478:TMEM18
gene id: 8478:TMEM18
uniprot id: A0A8C3ID21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

8478:HVCN1
gene id: 8478:HVCN1
uniprot id: A0A8C3F767
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

8478:LOC101936214
gene id: 8478:LOC101936214
uniprot id: A0A8C3HCY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.
messages: Secreted

8478:GALNT11
gene id: 8478:GALNT11
uniprot id: A0A8C3HYZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8478:DEF8
gene id: 8478:DEF8
uniprot id: A0A8C3HIY0
names: Similarity
messages: Belongs to the DEF8 family.

8478:IGF2BP3
gene id: 8478:IGF2BP3
uniprot id: A0A8C3PC96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Cytoplasm

8478:BPNT1
gene id: 8478:BPNT1
uniprot id: A0A8C3EZP5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8478:PPP4R2
gene id: 8478:PPP4R2
uniprot id: A0A8C3FFM6
uniprot id: A0A8C3FH21
names: Similarity
messages: Belongs to the PPP4R2 family.

8478:RAG2
gene id: 8478:RAG2
uniprot id: A0A8C3HEZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

8478:PTPRF
gene id: 8478:PTPRF
uniprot id: A0A8C3F6V0
uniprot id: A0A8C3F879
uniprot id: A0A8C3FBK6
uniprot id: A0A8C3FDJ1
uniprot id: A0A8C3FDN3
uniprot id: A0A8C3FDT6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

8478:GPD1L
gene id: 8478:GPD1L
uniprot id: A0A8C3ID12
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

8478:ENKUR
gene id: 8478:ENKUR
uniprot id: A0A8C3HPB3
names: Subcellular Location Annotation
messages: cilium axoneme

8478:FKBP4
gene id: 8478:FKBP4
uniprot id: A0A8C3HAI3
names: Subcellular Location Annotation
messages: Mitochondrion
messages: cytoskeleton
messages: cytosol

8478:SLC7A14
gene id: 8478:SLC7A14
uniprot id: A0A8C3HRF7
names: Subcellular Location Annotation
messages: Membrane

8478:SENP5
gene id: 8478:SENP5
uniprot id: A0A8C3F8N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

8478:IL18
gene id: 8478:IL18
uniprot id: A0A8C3FW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

8478:DNAJA2
gene id: 8478:DNAJA2
uniprot id: A0A8C3P7Z3
names: Subcellular Location Annotation
messages: Membrane

8478:MAP2K3
gene id: 8478:MAP2K3
uniprot id: A0A8C3I7M8
uniprot id: A0A8C3I8E8
uniprot id: A0A8C3I9R1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:RPL7
gene id: 8478:RPL7
uniprot id: A0A8C3FHB1
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

8478:SS18L2
gene id: 8478:SS18L2
uniprot id: A0A8C3H5X6
names: Similarity
messages: Belongs to the SS18 family.

8478:LOC101951468
gene id: 8478:LOC101951468
uniprot id: A0A8C3HLN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium

8478:LOC101943325
gene id: 8478:LOC101943325
uniprot id: A0A8C3J002
names: Similarity
messages: Belongs to the cytochrome P450 family.

8478:BZW2
gene id: 8478:BZW2
uniprot id: A0A8C3IAU8
names: Similarity
messages: Belongs to the BZW family.

8478:VANGL1
gene id: 8478:VANGL1
uniprot id: A0A8C3F556
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8478:CDH8
gene id: 8478:CDH8
uniprot id: A0A8C3FSF7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8478:BRINP3
gene id: 8478:BRINP3
uniprot id: A0A8C3HME9
uniprot id: A0A8C3P728
names: Similarity
messages: Belongs to the BRINP family.

8478:LOC101947913
gene id: 8478:LOC101947913
uniprot id: A0A8C3HT67
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8478:TAAR1
gene id: 8478:TAAR1
uniprot id: A0A8C3HYD2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:LIPG
gene id: 8478:LIPG
uniprot id: A0A8C3IN12
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8478:GET4
gene id: 8478:GET4
uniprot id: A0A8C3I8K5
names: Similarity
messages: Belongs to the GET4 family.

8478:LOC101933522
gene id: 8478:LOC101933522
uniprot id: A0A8C3F267
names: Similarity
messages: Belongs to the TPPP family.

8478:MAP3K13
gene id: 8478:MAP3K13
uniprot id: A0A8C3FIN0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8478:ALG2
gene id: 8478:ALG2
uniprot id: A0A8C3F512
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

8478:TBL1XR1
gene id: 8478:TBL1XR1
uniprot id: A0A8C3PFI9
names: Similarity
messages: Belongs to the WD repeat EBI family.

8478:ADCYAP1R1
gene id: 8478:ADCYAP1R1
uniprot id: A0A8C3FAP6
names: Subcellular Location Annotation
messages: Membrane

8478:PAM16
gene id: 8478:PAM16
uniprot id: A0A8C3IQJ0
names: Similarity
messages: Belongs to the TIM16/PAM16 family.

8478:ABCC9
gene id: 8478:ABCC9
uniprot id: A0A8C3FWV5
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

8478:MNS1
gene id: 8478:MNS1
uniprot id: A0A8C3F9T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

8478:MAPKAP1
gene id: 8478:MAPKAP1
uniprot id: A0A8C3IYF2
uniprot id: A0A8C3IYG9
uniprot id: A0A8C3J1B2
names: Similarity
messages: Belongs to the SIN1 family.

8478:MGME1
gene id: 8478:MGME1
uniprot id: A0A8C3IGG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGME1 family.
messages: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair.
messages: Mitochondrion

8478:ZDHHC3
gene id: 8478:ZDHHC3
uniprot id: A0A8C3IHY5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:CAB39
gene id: 8478:CAB39
uniprot id: A0A8C3I200
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8478:MPPED2
gene id: 8478:MPPED2
uniprot id: A0A8C3HC71
names: Similarity
messages: Belongs to the UPF0046 family.

8478:IL2RG
gene id: 8478:IL2RG
uniprot id: A0A8C3HUR0
names: Subcellular Location Annotation
messages: Membrane

8478:MAT2B
gene id: 8478:MAT2B
uniprot id: A0A8C3FTB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

8478:EIF2A
gene id: 8478:EIF2A
uniprot id: A0A8C3HLY6
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

8478:INKA2
gene id: 8478:INKA2
uniprot id: A0A8C3PBG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8478:SLC25A45
gene id: 8478:SLC25A45
uniprot id: A0A8C3IJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8478:PSMB1
gene id: 8478:PSMB1
uniprot id: A0A8C3FKR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8478:KCNA10
gene id: 8478:KCNA10
uniprot id: A0A8C3PE88
names: Subcellular Location Annotation
messages: Membrane

8478:BAMBI
gene id: 8478:BAMBI
uniprot id: A0A8C3HR13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

8478:ANXA2
gene id: 8478:ANXA2
uniprot id: A0A8C3P8P0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

8478:RPRD1A
gene id: 8478:RPRD1A
uniprot id: A0A8C3F602
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

8478:NOX1
gene id: 8478:NOX1
uniprot id: A0A8C3HL07
names: Subcellular Location Annotation
messages: Membrane

8478:GRAMD1A
gene id: 8478:GRAMD1A
uniprot id: A0A8C3FMK9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:SLC24A2
gene id: 8478:SLC24A2
uniprot id: A0A8C3I127
uniprot id: A0A8C3I2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8478:NDUFB10
gene id: 8478:NDUFB10
uniprot id: A0A8C3I942
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

8478:PCNX3
gene id: 8478:PCNX3
uniprot id: A0A8C3IGI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

8478:APLP2
gene id: 8478:APLP2
uniprot id: A0A8C3IUI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:FBXO25
gene id: 8478:FBXO25
uniprot id: A0A8C3IAS4
uniprot id: A0A8C3IDY3
names: Subcellular Location Annotation
messages: Nucleus

8478:HOXA4
gene id: 8478:HOXA4
uniprot id: A0A8C3IDT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8478:MRPL22
gene id: 8478:MRPL22
uniprot id: A0A8C3F355
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

8478:SNRPE
gene id: 8478:SNRPE
uniprot id: A0A8C3P8T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

8478:ALDH2
gene id: 8478:ALDH2
uniprot id: A0A8C3FCR3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8478:CNOT10
gene id: 8478:CNOT10
uniprot id: A0A8C3IDV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

8478:B3GALT6
gene id: 8478:B3GALT6
uniprot id: A0A8C3IC09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:LOC101945909
gene id: 8478:LOC101945909
uniprot id: A0A8C3I992
uniprot id: A0A8C3PB37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

8478:SLC6A7
gene id: 8478:SLC6A7
uniprot id: A0A8C3FZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8478:PTPRZ1
gene id: 8478:PTPRZ1
uniprot id: A0A8C3H9H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

8478:GPCPD1
gene id: 8478:GPCPD1
uniprot id: A0A8C3IIK5
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8478:RARRES1
gene id: 8478:RARRES1
uniprot id: A0A8C3HZQ2
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

8478:GJA8
gene id: 8478:GJA8
uniprot id: A0A8C3FEY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8478:P2RX4
gene id: 8478:P2RX4
uniprot id: A0A8C3IR90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8478:LOC101944482
gene id: 8478:LOC101944482
uniprot id: A0A8C3H8N2
names: Subcellular Location Annotation
messages: Membrane

8478:CDR2
gene id: 8478:CDR2
uniprot id: A0A8C3I1Z9
names: Similarity
messages: Belongs to the CDR2 family.

8478:LAMP3
gene id: 8478:LAMP3
uniprot id: A0A8C3H4Z2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

8478:TENM1
gene id: 8478:TENM1
uniprot id: A0A8C3P7A6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:IL13RA2
gene id: 8478:IL13RA2
uniprot id: A0A8C3HW08
names: Subcellular Location Annotation
messages: Membrane

8478:NTMT1
gene id: 8478:NTMT1
uniprot id: A0A8C3IDW7
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

8478:LOC101953236
gene id: 8478:LOC101953236
uniprot id: A0A8C3HV25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:HYOU1
gene id: 8478:HYOU1
uniprot id: A0A8C3FA26
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8478:DZIP1L
gene id: 8478:DZIP1L
uniprot id: A0A8C3EYN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: cilium basal body

8478:SART1
gene id: 8478:SART1
uniprot id: A0A8C3PCY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

8478:ARL6IP4
gene id: 8478:ARL6IP4
uniprot id: A0A8C3IR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

8478:GINS3
gene id: 8478:GINS3
uniprot id: A0A8C3IUN5
uniprot id: A0A8C3IWI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

8478:POU1F1
gene id: 8478:POU1F1
uniprot id: A0A8C3IZB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8478:CD34
gene id: 8478:CD34
uniprot id: A0A8C3IMI8
names: Subcellular Location Annotation
messages: Membrane

8478:IRX3
gene id: 8478:IRX3
uniprot id: A0A8C3HDQ4
uniprot id: A0A8C3HDT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8478:NUDT1
gene id: 8478:NUDT1
uniprot id: A0A8C3I6U2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

8478:MYMK
gene id: 8478:MYMK
uniprot id: A0A8C3IAM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

8478:RAB4A
gene id: 8478:RAB4A
uniprot id: A0A8C3FFT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

8478:CERCAM
gene id: 8478:CERCAM
uniprot id: A0A8C3IQ55
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8478:ISM1
gene id: 8478:ISM1
uniprot id: A0A8C3PCV8
names: Similarity
messages: Belongs to the isthmin family.

8478:CREG1
gene id: 8478:CREG1
uniprot id: A0A8C3FED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

8478:TUT1
gene id: 8478:TUT1
uniprot id: A0A8C3HYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Nucleus speckle
messages: nucleolus

8478:TINAGL1
gene id: 8478:TINAGL1
uniprot id: A0A8C3P9V0
names: Similarity
messages: Belongs to the peptidase C1 family.

8478:PPFIA1
gene id: 8478:PPFIA1
uniprot id: A0A8C3HEQ4
uniprot id: A0A8C3P420
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

8478:JPH3
gene id: 8478:JPH3
uniprot id: A0A8C3IGN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8478:PDC
gene id: 8478:PDC
uniprot id: A0A8C3HMK1
names: Similarity
messages: Belongs to the phosducin family.

8478:CEP43
gene id: 8478:CEP43
uniprot id: A0A8C3HEW1
uniprot id: A0A8C3HEY6
uniprot id: A0A8C3HF31
uniprot id: A0A8C3HF55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

8478:ALG8
gene id: 8478:ALG8
uniprot id: A0A8C3IWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:LOC101946150
gene id: 8478:LOC101946150
uniprot id: A0A8C3PG49
names: Subcellular Location Annotation
messages: cytoskeleton

8478:TRMT6
gene id: 8478:TRMT6
uniprot id: A0A8C3IGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

8478:ETFRF1
gene id: 8478:ETFRF1
uniprot id: A0A8C3FQF2
names: Similarity
messages: Belongs to the complex I LYR family.

8478:PEX16
gene id: 8478:PEX16
uniprot id: A0A8C3P4C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

8478:NUP133
gene id: 8478:NUP133
uniprot id: A0A8C3FEK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

8478:TMCC2
gene id: 8478:TMCC2
uniprot id: A0A8C3F3S8
names: Similarity
messages: Belongs to the TEX28 family.

8478:LMX1B
gene id: 8478:LMX1B
uniprot id: A0A8C3IX61
names: Subcellular Location Annotation
messages: Nucleus

8478:RPS12
gene id: 8478:RPS12
uniprot id: A0A8C3P916
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

8478:ARPC5L
gene id: 8478:ARPC5L
uniprot id: A0A8C3J0V9
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

8478:GASK1A
gene id: 8478:GASK1A
uniprot id: A0A8C3ID69
uniprot id: A0A8C3IG94
names: Similarity
messages: Belongs to the GASK family.

8478:LOC101936497
gene id: 8478:LOC101936497
uniprot id: A0A8C3PDI3
names: Subcellular Location Annotation
messages: Membrane

8478:TLR5
gene id: 8478:TLR5
uniprot id: A0A8C3HEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8478:SLC26A4
gene id: 8478:SLC26A4
uniprot id: A0A8C3F160
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sodium-independent transporter of chloride and iodide.

8478:CA2
gene id: 8478:CA2
uniprot id: A0A8C3FQP7
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8478:GCSH
gene id: 8478:GCSH
uniprot id: A0A8C3IJ30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8478:DLGAP2
gene id: 8478:DLGAP2
uniprot id: A0A8C3IAU3
names: Similarity
messages: Belongs to the SAPAP family.

8478:MED12L
gene id: 8478:MED12L
uniprot id: A0A8C3I0C6
uniprot id: A0A8C3I0H2
uniprot id: A0A8C3P9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

8478:FMR1
gene id: 8478:FMR1
uniprot id: A0A8C3I7I4
uniprot id: A0A8C3I854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Stress granule
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

8478:CHST13
gene id: 8478:CHST13
uniprot id: A0A8C3HLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:AKAP12
gene id: 8478:AKAP12
uniprot id: A0A8C3HT53
uniprot id: A0A8C3HT90
names: Subcellular Location Annotation
messages: Membrane

8478:NDRG4
gene id: 8478:NDRG4
uniprot id: A0A8C3ISL0
uniprot id: A0A8C3ITR0
uniprot id: A0A8C3IU56
uniprot id: A0A8C3PFF1
names: Similarity
messages: Belongs to the NDRG family.

8478:ARF4
gene id: 8478:ARF4
uniprot id: A0A8C3HE65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8478:PPP1R14C
gene id: 8478:PPP1R14C
uniprot id: A0A8C3HTE0
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8478:LOC101947716
gene id: 8478:LOC101947716
uniprot id: A0A8C3IFR4
names: Similarity
messages: Belongs to the TMEM121 family.

8478:DDX6
gene id: 8478:DDX6
uniprot id: A0A8C3H7G8
names: Similarity
messages: Belongs to the DEAD box helicase family.

8478:DIABLO
gene id: 8478:DIABLO
uniprot id: A0A8C3IQV0
names: Subcellular Location Annotation
messages: Mitochondrion

8478:TF
gene id: 8478:TF
uniprot id: A0A8C3IBH2
names: Similarity
messages: Belongs to the transferrin family.

8478:ATP6V0D2
gene id: 8478:ATP6V0D2
uniprot id: A0A8C3HAQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8478:GCLC
gene id: 8478:GCLC
uniprot id: A0A8C3IBD0
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

8478:MYB
gene id: 8478:MYB
uniprot id: A0A8C3HWK5
uniprot id: A0A8C3HWL5
names: Subcellular Location Annotation
messages: Nucleus

8478:DLGAP3
gene id: 8478:DLGAP3
uniprot id: A0A8C3I064
names: Similarity
messages: Belongs to the SAPAP family.

8478:TUBB3
gene id: 8478:TUBB3
uniprot id: A0A8C3P665
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8478:MOCOS
gene id: 8478:MOCOS
uniprot id: A0A8C3F6N1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

8478:LYPLAL1
gene id: 8478:LYPLAL1
uniprot id: A0A8C3HG87
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

8478:RSL24D1
gene id: 8478:RSL24D1
uniprot id: A0A8C3FAI9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

8478:THBD
gene id: 8478:THBD
uniprot id: A0A8C3IG48
names: Caution
names: Function
names: Subunit
messages: Interacts with ITGAL, ITGAM and ITGB2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

8478:DPT
gene id: 8478:DPT
uniprot id: A0A8C3H6Q4
names: Similarity
messages: Belongs to the dermatopontin family.

8478:BCL2L10
gene id: 8478:BCL2L10
uniprot id: A0A8C3IX63
names: Similarity
messages: Belongs to the Bcl-2 family.

8478:EXOC5
gene id: 8478:EXOC5
uniprot id: A0A8C3IL76
names: Similarity
messages: Belongs to the SEC10 family.

8478:CDK14
gene id: 8478:CDK14
uniprot id: A0A8C3I9T5
uniprot id: A0A8C3ICZ7
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:GPR37
gene id: 8478:GPR37
uniprot id: A0A8C3I755
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8478:TSPO2
gene id: 8478:TSPO2
uniprot id: A0A8C3HW41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

8478:GNG4
gene id: 8478:GNG4
uniprot id: A0A8C3H719
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8478:AMOT
gene id: 8478:AMOT
uniprot id: A0A8C3HVG7
names: Similarity
messages: Belongs to the angiomotin family.

8478:TAF9B
gene id: 8478:TAF9B
uniprot id: A0A8C3P6T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

8478:EOMES
gene id: 8478:EOMES
uniprot id: A0A8C3IGY6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8478:TMEM39A
gene id: 8478:TMEM39A
uniprot id: A0A8C3F6T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

8478:CAMLG
gene id: 8478:CAMLG
uniprot id: A0A8C3FM67
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

8478:USP15
gene id: 8478:USP15
uniprot id: A0A8C3F2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

8478:MFN2
gene id: 8478:MFN2
uniprot id: A0A8C3IEH4
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8478:B3GNT9
gene id: 8478:B3GNT9
uniprot id: A0A8C3P309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:ELOVL4
gene id: 8478:ELOVL4
uniprot id: A0A8C3IFC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Oligomer.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

8478:GALNT9
gene id: 8478:GALNT9
uniprot id: A0A8C3IKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8478:SF3B5
gene id: 8478:SF3B5
uniprot id: A0A8C3HWA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

8478:COPS5
gene id: 8478:COPS5
uniprot id: A0A8C3HKB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

8478:LOC101938916
gene id: 8478:LOC101938916
uniprot id: A0A8C3F9M1
names: Similarity
messages: Belongs to the intercrine gamma family.

8478:LONP2
gene id: 8478:LONP2
uniprot id: A0A8C3HRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

8478:MAF
gene id: 8478:MAF
uniprot id: A0A8C3FQ89
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8478:LMOD3
gene id: 8478:LMOD3
uniprot id: A0A8C3EY48
names: Subcellular Location Annotation
messages: cytoskeleton

8478:C20H9orf116
gene id: 8478:C20H9orf116
uniprot id: A0A8C3I7J3
names: Subcellular Location Annotation
messages: cilium axoneme

8478:FOXL2
gene id: 8478:FOXL2
uniprot id: A0A8C3I224
names: Subcellular Location Annotation
messages: Nucleus

8478:GAP43
gene id: 8478:GAP43
uniprot id: A0A8C3FB29
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Cell membrane
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: filopodium membrane
messages: growth cone membrane

8478:LOC101933963
gene id: 8478:LOC101933963
uniprot id: A0A8C3P744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

8478:ELAVL2
gene id: 8478:ELAVL2
uniprot id: A0A8C3H9J9
uniprot id: A0A8C3H9K1
names: Similarity
messages: Belongs to the RRM elav family.

8478:SURF4
gene id: 8478:SURF4
uniprot id: A0A8C3IBI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:IRF8
gene id: 8478:IRF8
uniprot id: A0A8C3IHK1
names: Subcellular Location Annotation
messages: Nucleus

8478:BTG2
gene id: 8478:BTG2
uniprot id: A0A8C3HVY4
names: Similarity
messages: Belongs to the BTG family.

8478:CDC25A
gene id: 8478:CDC25A
uniprot id: A0A8C3P7D2
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

8478:GABRG2
gene id: 8478:GABRG2
uniprot id: A0A8C3FME8
uniprot id: A0A8C3FPE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8478:STX7
gene id: 8478:STX7
uniprot id: A0A8C3P921
names: Similarity
messages: Belongs to the syntaxin family.

8478:BICD2
gene id: 8478:BICD2
uniprot id: A0A8C3IEZ0
names: Similarity
messages: Belongs to the BicD family.

8478:LOC101935282
gene id: 8478:LOC101935282
uniprot id: A0A8C3HZK4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Component of the 40S small ribosomal subunit.

8478:LIN7C
gene id: 8478:LIN7C
uniprot id: A0A8C3H691
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8478:TTC27
gene id: 8478:TTC27
uniprot id: A0A8C3IM73
names: Similarity
messages: Belongs to the TTC27 family.

8478:MRPL53
gene id: 8478:MRPL53
uniprot id: A0A8C3FJ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

8478:CIAO2B
gene id: 8478:CIAO2B
uniprot id: A0A8C3P390
names: Similarity
messages: Belongs to the MIP18 family.

8478:RBPMS2
gene id: 8478:RBPMS2
uniprot id: A0A8C3FEB9
names: Subcellular Location Annotation
messages: Cytoplasm

8478:INSIG1
gene id: 8478:INSIG1
uniprot id: A0A8C3I027
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

8478:RSPO3
gene id: 8478:RSPO3
uniprot id: A0A8C3HZF6
names: Similarity
messages: Belongs to the R-spondin family.

8478:ARL8B
gene id: 8478:ARL8B
uniprot id: A0A8C3HNM4
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8478:STRA6
gene id: 8478:STRA6
uniprot id: A0A8C3FR70
uniprot id: A0A8C3FV67
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8478:ST6GAL2
gene id: 8478:ST6GAL2
uniprot id: A0A8C3FJ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8478:L3MBTL3
gene id: 8478:L3MBTL3
uniprot id: A0A8C3HYY3
names: Subcellular Location Annotation
messages: Nucleus

8478:MDFIC
gene id: 8478:MDFIC
uniprot id: A0A8C3H941
names: Similarity
messages: Belongs to the MDFI family.

8478:CRYGN
gene id: 8478:CRYGN
uniprot id: A0A8C3HYT3
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

8478:KIF27
gene id: 8478:KIF27
uniprot id: A0A8C3INI6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8478:TMEM87A
gene id: 8478:TMEM87A
uniprot id: A0A8C3FX05
names: Subcellular Location Annotation
messages: Membrane

8478:PFKFB2
gene id: 8478:PFKFB2
uniprot id: A0A8C3H683
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8478:CMTM6
gene id: 8478:CMTM6
uniprot id: A0A8C3IDU6
names: Subcellular Location Annotation
messages: Membrane

8478:THRAP3
gene id: 8478:THRAP3
uniprot id: A0A8C3I086
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

8478:PTPN14
gene id: 8478:PTPN14
uniprot id: A0A8C3HGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

8478:ST3GAL3
gene id: 8478:ST3GAL3
uniprot id: A0A8C3F710
uniprot id: A0A8C3F721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8478:CMKLR1
gene id: 8478:CMKLR1
uniprot id: A0A8C3FGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

8478:TRMT2A
gene id: 8478:TRMT2A
uniprot id: A0A8C3HUL6
uniprot id: A0A8C3HVJ2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:CAT
gene id: 8478:CAT
uniprot id: A0A8C3HER0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

8478:FAM13B
gene id: 8478:FAM13B
uniprot id: A0A8C3FMW3
uniprot id: A0A8C3H9S0
names: Similarity
messages: Belongs to the FAM13 family.

8478:PTP4A1
gene id: 8478:PTP4A1
uniprot id: A0A8C3IEH2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8478:LAMB1
gene id: 8478:LAMB1
uniprot id: A0A8C3H5H0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8478:DNM1L
gene id: 8478:DNM1L
uniprot id: A0A8C3I6K8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8478:DDIT3
gene id: 8478:DDIT3
uniprot id: A0A8C3HWB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

8478:CAPN7
gene id: 8478:CAPN7
uniprot id: A0A8C3IHE1
names: Similarity
messages: Belongs to the peptidase C2 family.

8478:TMEM182
gene id: 8478:TMEM182
uniprot id: A0A8C3FLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

8478:YIPF6
gene id: 8478:YIPF6
uniprot id: A0A8C3FJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:TLE1
gene id: 8478:TLE1
uniprot id: A0A8C3I1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8478:CCZ1
gene id: 8478:CCZ1
uniprot id: A0A8C3I7G4
names: Similarity
messages: Belongs to the CCZ1 family.

8478:LOC101941719
gene id: 8478:LOC101941719
uniprot id: A0A8C3P6V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8478:NPHS2
gene id: 8478:NPHS2
uniprot id: A0A8C3IS74
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8478:TBPL1
gene id: 8478:TBPL1
uniprot id: A0A8C3P910
names: Similarity
messages: Belongs to the TBP family.

8478:SLC10A7
gene id: 8478:SLC10A7
uniprot id: A0A8C3PFU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8478:TRAPPC2L
gene id: 8478:TRAPPC2L
uniprot id: A0A8C3IIN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

8478:ACAD8
gene id: 8478:ACAD8
uniprot id: A0A8C3HX69
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8478:RAB19
gene id: 8478:RAB19
uniprot id: A0A8C3HCX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

8478:MON1A
gene id: 8478:MON1A
uniprot id: A0A8C3F4G7
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

8478:DCBLD2
gene id: 8478:DCBLD2
uniprot id: A0A8C3FBT6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:BCAT1
gene id: 8478:BCAT1
uniprot id: A0A8C3FP11
uniprot id: A0A8C3FQ24
uniprot id: A0A8C3FWJ5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

8478:WNK1
gene id: 8478:WNK1
uniprot id: A0A8C3IVY4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8478:RNF13
gene id: 8478:RNF13
uniprot id: A0A8C3HL99
names: Subcellular Location Annotation
messages: Membrane

8478:RC3H1
gene id: 8478:RC3H1
uniprot id: A0A8C3P709
names: Subcellular Location Annotation
messages: P-body

8478:LOC101943319
gene id: 8478:LOC101943319
uniprot id: A0A8C3IMV8
names: Subcellular Location Annotation
messages: Membrane

8478:DRAM1
gene id: 8478:DRAM1
uniprot id: A0A8C3F4D4
names: Subcellular Location Annotation
messages: Membrane

8478:MAD1L1
gene id: 8478:MAD1L1
uniprot id: A0A8C3PB10
names: Similarity
messages: Belongs to the MAD1 family.

8478:MRPS33
gene id: 8478:MRPS33
uniprot id: A0A8C3HCK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

8478:SCG2
gene id: 8478:SCG2
uniprot id: A0A8C3I2M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

8478:CLDN18
gene id: 8478:CLDN18
uniprot id: A0A8C3H5D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8478:VAT1L
gene id: 8478:VAT1L
uniprot id: A0A8C3FRD4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8478:PDHX
gene id: 8478:PDHX
uniprot id: A0A8C3HF16
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

8478:NTNG2
gene id: 8478:NTNG2
uniprot id: A0A8C3I864
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:CACFD1
gene id: 8478:CACFD1
uniprot id: A0A8C3I7W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

8478:ITM2A
gene id: 8478:ITM2A
uniprot id: A0A8C3HM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8478:RCL1
gene id: 8478:RCL1
uniprot id: A0A8C3IPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

8478:KLC4
gene id: 8478:KLC4
uniprot id: A0A8C3F786
uniprot id: A0A8C3FAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8478:HPGD
gene id: 8478:HPGD
uniprot id: A0A8C3IMS9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8478:ARHGEF6
gene id: 8478:ARHGEF6
uniprot id: A0A8C3IPL0
names: Subcellular Location Annotation
messages: lamellipodium

8478:GJA5
gene id: 8478:GJA5
uniprot id: A0A8C3H848
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8478:ORC1
gene id: 8478:ORC1
uniprot id: A0A8C3HMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

8478:BCLAF1
gene id: 8478:BCLAF1
uniprot id: A0A8C3HWJ3
uniprot id: A0A8C3HWJ8
uniprot id: A0A8C3HX25
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

8478:HTR5A
gene id: 8478:HTR5A
uniprot id: A0A8C3HZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:POMGNT2
gene id: 8478:POMGNT2
uniprot id: A0A8C3PCH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:RER1
gene id: 8478:RER1
uniprot id: A0A8C3IA28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

8478:TMEM43
gene id: 8478:TMEM43
uniprot id: A0A8C3HM82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

8478:ZNF330
gene id: 8478:ZNF330
uniprot id: A0A8C3IUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

8478:SGCD
gene id: 8478:SGCD
uniprot id: A0A8C3FAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

8478:LRRC8A
gene id: 8478:LRRC8A
uniprot id: A0A8C3III1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8478:NONO
gene id: 8478:NONO
uniprot id: A0A8C3HTN4
names: Subcellular Location Annotation
messages: Nucleus speckle

8478:SOAT1
gene id: 8478:SOAT1
uniprot id: A0A8C3IQK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:TES
gene id: 8478:TES
uniprot id: A0A8C3FJ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

8478:TM2D3
gene id: 8478:TM2D3
uniprot id: A0A8C3FXU7
uniprot id: A0A8C3HBH8
names: Subcellular Location Annotation
messages: Membrane

8478:NDUFB6
gene id: 8478:NDUFB6
uniprot id: A0A8C3H9C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8478:LOC122172113
gene id: 8478:LOC122172113
uniprot id: A0A8C3HX11
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

8478:CELF1
gene id: 8478:CELF1
uniprot id: A0A8C3IEB6
uniprot id: A0A8C3IEG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

8478:POLH
gene id: 8478:POLH
uniprot id: A0A8C3INC0
names: Subcellular Location Annotation
messages: Nucleus

8478:LOC101941978
gene id: 8478:LOC101941978
uniprot id: A0A8C3HY33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8478:LOC101952464
gene id: 8478:LOC101952464
uniprot id: A0A8C3I8R0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

8478:SPA17
gene id: 8478:SPA17
uniprot id: A0A8C3FX95
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.

8478:RRS1
gene id: 8478:RRS1
uniprot id: A0A8C3ICC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

8478:SLC2A12
gene id: 8478:SLC2A12
uniprot id: A0A8C3HWY6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8478:LOC101936113
gene id: 8478:LOC101936113
uniprot id: A0A8C3EYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8478:CYLD
gene id: 8478:CYLD
uniprot id: A0A8C3P7V8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

8478:NR2C2
gene id: 8478:NR2C2
uniprot id: A0A8C3HLT8
uniprot id: A0A8C3HLW0
uniprot id: A0A8C3HLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8478:SIAH1
gene id: 8478:SIAH1
uniprot id: A0A8C3HSJ1
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

8478:PAMR1
gene id: 8478:PAMR1
uniprot id: A0A8C3HEV7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:PGK1
gene id: 8478:PGK1
uniprot id: A0A8C3HV08
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

8478:CWF19L2
gene id: 8478:CWF19L2
uniprot id: A0A8C3HZY7
names: Similarity
messages: Belongs to the CWF19 family.

8478:LOC101951992
gene id: 8478:LOC101951992
uniprot id: A0A8C3EYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8478:TRAK1
gene id: 8478:TRAK1
uniprot id: A0A8C3IFP4
uniprot id: A0A8C3PCW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

8478:LOC101935334
gene id: 8478:LOC101935334
uniprot id: A0A8C3FER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:CMTR1
gene id: 8478:CMTR1
uniprot id: A0A8C3IN82
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

8478:RAB3GAP2
gene id: 8478:RAB3GAP2
uniprot id: A0A8C3EY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP regulatory subunit family.
messages: Cytoplasm

8478:SLC6A15
gene id: 8478:SLC6A15
uniprot id: A0A8C3H4P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

8478:LOC101950173
gene id: 8478:LOC101950173
uniprot id: A0A8C3H6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8478:WLS
gene id: 8478:WLS
uniprot id: A0A8C3F2H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

8478:EIF5A2
gene id: 8478:EIF5A2
uniprot id: A0A8C3HS32
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

8478:ZFPL1
gene id: 8478:ZFPL1
uniprot id: A0A8C3IJF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZFPL1 family.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

8478:LGR4
gene id: 8478:LGR4
uniprot id: A0A8C3F953
names: Subcellular Location Annotation
messages: Membrane

8478:OPHN1
gene id: 8478:OPHN1
uniprot id: A0A8C3FIM5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Postsynapse
messages: Presynapse
messages: dendrite

8478:ZDHHC15
gene id: 8478:ZDHHC15
uniprot id: A0A8C3P759
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:SLC17A5
gene id: 8478:SLC17A5
uniprot id: A0A8C3II23
names: Subcellular Location Annotation
messages: Membrane

8478:TSPAN11
gene id: 8478:TSPAN11
uniprot id: A0A8C3FR64
uniprot id: A0A8C3FVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:LOC101938847
gene id: 8478:LOC101938847
uniprot id: A0A8C3H976
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8478:DGKZ
gene id: 8478:DGKZ
uniprot id: A0A8C3HF58
uniprot id: A0A8C3HF63
uniprot id: A0A8C3HFA0
uniprot id: A0A8C3HFC1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8478:LOC101933606
gene id: 8478:LOC101933606
uniprot id: A0A8C3FCR1
uniprot id: A0A8C3H7N0
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

8478:AQP9
gene id: 8478:AQP9
uniprot id: A0A8C3FGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8478:CALCR
gene id: 8478:CALCR
uniprot id: A0A8C3IKA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

8478:PCSK7
gene id: 8478:PCSK7
uniprot id: A0A8C3I8U8
names: Similarity
messages: Belongs to the peptidase S8 family.

8478:PSAT1
gene id: 8478:PSAT1
uniprot id: A0A8C3I1E3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

8478:SNX10
gene id: 8478:SNX10
uniprot id: A0A8C3PCA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8478:NKX2-2
gene id: 8478:NKX2-2
uniprot id: A0A8C3IJ09
names: Subcellular Location Annotation
messages: Nucleus

8478:NCOA1
gene id: 8478:NCOA1
uniprot id: A0A8C3IC79
uniprot id: A0A8C3ICZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

8478:RHO
gene id: 8478:RHO
uniprot id: A0A8C3P702
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

8478:RPL22
gene id: 8478:RPL22
uniprot id: A0A8C3I344
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

8478:AMFR
gene id: 8478:AMFR
uniprot id: A0A8C3HD33
uniprot id: A0A8C3P2W4
names: Subcellular Location Annotation
messages: Membrane

8478:LOC101944735
gene id: 8478:LOC101944735
uniprot id: A0A8C3PBY4
names: Subcellular Location Annotation
messages: Secreted

8478:CLIC5
gene id: 8478:CLIC5
uniprot id: A0A8C3IB03
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8478:ARV1
gene id: 8478:ARV1
uniprot id: A0A8C3FIL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

8478:MBD4
gene id: 8478:MBD4
uniprot id: A0A8C3HMT1
names: Subcellular Location Annotation
messages: Nucleus

8478:LEPR
gene id: 8478:LEPR
uniprot id: A0A8C3F1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

8478:GPR137
gene id: 8478:GPR137
uniprot id: A0A8C3IIQ0
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8478:KCNAB2
gene id: 8478:KCNAB2
uniprot id: A0A8C3I2N2
uniprot id: A0A8C3I5E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

8478:XPO6
gene id: 8478:XPO6
uniprot id: A0A8C3ILB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

8478:LOC101938274
gene id: 8478:LOC101938274
uniprot id: A0A8C3HAK7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

8478:CENPN
gene id: 8478:CENPN
uniprot id: A0A8C3III5
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

8478:JAKMIP2
gene id: 8478:JAKMIP2
uniprot id: A0A8C3FK78
names: Similarity
messages: Belongs to the JAKMIP family.

8478:TAFA4
gene id: 8478:TAFA4
uniprot id: A0A8C3H4S1
names: Similarity
messages: Belongs to the TAFA family.

8478:PDCL
gene id: 8478:PDCL
uniprot id: A0A8C3HAX1
names: Similarity
messages: Belongs to the phosducin family.

8478:PRKAR1B
gene id: 8478:PRKAR1B
uniprot id: A0A8C3I5V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8478:DENND5B
gene id: 8478:DENND5B
uniprot id: A0A8C3IXJ9
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:NUDT2
gene id: 8478:NUDT2
uniprot id: A0A8C3H7Z6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

8478:CDH6
gene id: 8478:CDH6
uniprot id: A0A8C3F3K7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8478:DCTN4
gene id: 8478:DCTN4
uniprot id: A0A8C3FSB8
uniprot id: A0A8C3FVL8
uniprot id: A0A8C3HB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunit 4 family.
messages: cell cortex
messages: centrosome
messages: sarcomere
messages: stress fiber

8478:BUD31
gene id: 8478:BUD31
uniprot id: A0A8C3I7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

8478:LOC101953571
gene id: 8478:LOC101953571
uniprot id: A0A8C3EX75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8478:POMC
gene id: 8478:POMC
uniprot id: A0A8C3PC56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8478:SLC7A11
gene id: 8478:SLC7A11
uniprot id: A0A8C3IX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

8478:UBALD1
gene id: 8478:UBALD1
uniprot id: A0A8C3HCG2
names: Similarity
messages: Belongs to the UBALD family.

8478:DPF3
gene id: 8478:DPF3
uniprot id: A0A8C3FWR1
names: Similarity
messages: Belongs to the requiem/DPF family.

8478:LOC101943025
gene id: 8478:LOC101943025
uniprot id: A0A8C3I144
names: Similarity
messages: Belongs to the cornifelin family.

8478:UBE4B
gene id: 8478:UBE4B
uniprot id: A0A8C3IBK5
uniprot id: A0A8C3IBM6
uniprot id: A0A8C3PC07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

8478:UBE2A
gene id: 8478:UBE2A
uniprot id: A0A8C3I938
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8478:PSME3IP1
gene id: 8478:PSME3IP1
uniprot id: A0A8C3IWD6
names: Subcellular Location Annotation
messages: Nucleus

8478:TYRP1
gene id: 8478:TYRP1
uniprot id: A0A8C3IQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

8478:TTC9
gene id: 8478:TTC9
uniprot id: A0A8C3IEP0
names: Similarity
messages: Belongs to the TTC9 family.

8478:SNTB2
gene id: 8478:SNTB2
uniprot id: A0A8C3IUB0
names: Subcellular Location Annotation
messages: Cell junction

8478:UBE2L6
gene id: 8478:UBE2L6
uniprot id: A0A8C3HU69
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8478:ENDOG
gene id: 8478:ENDOG
uniprot id: A0A8C3IF86
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

8478:BCL2L14
gene id: 8478:BCL2L14
uniprot id: A0A8C3II88
names: Similarity
messages: Belongs to the Bcl-2 family.

8478:PPIL4
gene id: 8478:PPIL4
uniprot id: A0A8C3HTH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8478:TSEN2
gene id: 8478:TSEN2
uniprot id: A0A8C3IRX2
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.

8478:GTF3C5
gene id: 8478:GTF3C5
uniprot id: A0A8C3I8J9
names: Subcellular Location Annotation
messages: Nucleus

8478:EGFR
gene id: 8478:EGFR
uniprot id: A0A8C3IL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8478:ERGIC1
gene id: 8478:ERGIC1
uniprot id: A0A8C3FRL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8478:LOC101936037
gene id: 8478:LOC101936037
uniprot id: A0A8C3I8W5
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

8478:RPS14
gene id: 8478:RPS14
uniprot id: A0A8C3FU65
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

8478:FAM199X
gene id: 8478:FAM199X
uniprot id: A0A8C3IA77
names: Similarity
messages: Belongs to the FAM199 family.

8478:PEX5L
gene id: 8478:PEX5L
uniprot id: A0A8C3PFG1
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

8478:IRF1
gene id: 8478:IRF1
uniprot id: A0A8C3HTT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

8478:XPOT
gene id: 8478:XPOT
uniprot id: A0A8C3F5I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

8478:ATP5F1A
gene id: 8478:ATP5F1A
uniprot id: A0A8C3IPC0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

8478:TMEM242
gene id: 8478:TMEM242
uniprot id: A0A8C3HSD9
uniprot id: A0A8C3HSF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

8478:SLC9A4
gene id: 8478:SLC9A4
uniprot id: A0A8C3H8T8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Interacts with CHP1 and CHP2.
messages: Membrane

8478:THYN1
gene id: 8478:THYN1
uniprot id: A0A8C3P925
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8478:DRD2
gene id: 8478:DRD2
uniprot id: A0A8C3FPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:LZTFL1
gene id: 8478:LZTFL1
uniprot id: A0A8C3IFW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

8478:EPN2
gene id: 8478:EPN2
uniprot id: A0A8C3I8X7
names: Similarity
messages: Belongs to the epsin family.

8478:TELO2
gene id: 8478:TELO2
uniprot id: A0A8C3EZ29
names: Similarity
messages: Belongs to the TEL2 family.

8478:LFNG
gene id: 8478:LFNG
uniprot id: A0A8C3I6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:UNG
gene id: 8478:UNG
uniprot id: A0A8C3FHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

8478:CD74
gene id: 8478:CD74
uniprot id: A0A8C3FS90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:COLGALT2
gene id: 8478:COLGALT2
uniprot id: A0A8C3HQF8
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8478:PRTFDC1
gene id: 8478:PRTFDC1
uniprot id: A0A8C3HPB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

8478:SLC39A10
gene id: 8478:SLC39A10
uniprot id: A0A8C3IAI4
names: Subcellular Location Annotation
messages: Membrane

8478:PSMB7
gene id: 8478:PSMB7
uniprot id: A0A8C3IY53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8478:OGFOD1
gene id: 8478:OGFOD1
uniprot id: A0A8C3P2X6
names: Similarity
messages: Belongs to the TPA1 family.

8478:ATAD2B
gene id: 8478:ATAD2B
uniprot id: A0A8C3I7M7
names: Similarity
messages: Belongs to the AAA ATPase family.

8478:METTL15
gene id: 8478:METTL15
uniprot id: A0A8C3HCK9
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

8478:GDPD4
gene id: 8478:GDPD4
uniprot id: A0A8C3J159
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8478:FARSB
gene id: 8478:FARSB
uniprot id: A0A8C3I2C1
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

8478:KIF4A
gene id: 8478:KIF4A
uniprot id: A0A8C3HL35
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8478:FAM167A
gene id: 8478:FAM167A
uniprot id: A0A8C3I835
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

8478:GRAMD1B
gene id: 8478:GRAMD1B
uniprot id: A0A8C3HNT2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:CNIH2
gene id: 8478:CNIH2
uniprot id: A0A8C3IFA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8478:TIMM10
gene id: 8478:TIMM10
uniprot id: A0A8C3HV21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8478:ARL5B
gene id: 8478:ARL5B
uniprot id: A0A8C3HPT9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8478:GLRA1
gene id: 8478:GLRA1
uniprot id: A0A8C3FW29
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

8478:LSM14A
gene id: 8478:LSM14A
uniprot id: A0A8C3H5F2
names: Similarity
messages: Belongs to the LSM14 family.

8478:ENO1
gene id: 8478:ENO1
uniprot id: A0A8C3IBL0
uniprot id: A0A8C3IDY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

8478:WNT3A
gene id: 8478:WNT3A
uniprot id: A0A8C3H624
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8478:IARS2
gene id: 8478:IARS2
uniprot id: A0A8C3EZK4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8478:TGFB2
gene id: 8478:TGFB2
uniprot id: A0A8C3HGG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

8478:MYF5
gene id: 8478:MYF5
uniprot id: A0A8C3EZ00
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8478:PRKCB
gene id: 8478:PRKCB
uniprot id: A0A8C3F4M5
uniprot id: A0A8C3H640
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

8478:ABCB7
gene id: 8478:ABCB7
uniprot id: A0A8C3HMT0
names: Subcellular Location Annotation
messages: Membrane

8478:ASF1A
gene id: 8478:ASF1A
uniprot id: A0A8C3I0G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

8478:ANAPC5
gene id: 8478:ANAPC5
uniprot id: A0A8C3IPE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

8478:HEBP2
gene id: 8478:HEBP2
uniprot id: A0A8C3HVC8
names: Similarity
messages: Belongs to the HEBP family.

8478:LOC101937026
gene id: 8478:LOC101937026
uniprot id: A0A8C3I447
uniprot id: A0A8C3PAC7
names: Similarity
messages: Belongs to the AKAP110 family.

8478:YARS2
gene id: 8478:YARS2
uniprot id: A0A8C3I5Z5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8478:TGM4
gene id: 8478:TGM4
uniprot id: A0A8C3IG59
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8478:GALNS
gene id: 8478:GALNS
uniprot id: A0A8C3IG75
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Homodimer.
messages: Lysosome

8478:NKX6-3
gene id: 8478:NKX6-3
uniprot id: A0A8C3FCV9
names: Subcellular Location Annotation
messages: Nucleus

8478:SLC25A38
gene id: 8478:SLC25A38
uniprot id: A0A8C3EYW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

8478:ITGB1
gene id: 8478:ITGB1
uniprot id: A0A8C3HVP9
uniprot id: A0A8C3HWX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

8478:PPP1R15B
gene id: 8478:PPP1R15B
uniprot id: A0A8C3HVN9
names: Similarity
messages: Belongs to the PPP1R15 family.

8478:DAZAP2
gene id: 8478:DAZAP2
uniprot id: A0A8C3HZS9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

8478:TGFBR1
gene id: 8478:TGFBR1
uniprot id: A0A8C3F0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8478:INSIG2
gene id: 8478:INSIG2
uniprot id: A0A8C3FTM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

8478:LOC101934340
gene id: 8478:LOC101934340
uniprot id: A0A8C3FR94
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:ADAM17
gene id: 8478:ADAM17
uniprot id: A0A8C3HKK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:AK3
gene id: 8478:AK3
uniprot id: A0A8C3IR44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

8478:DTYMK
gene id: 8478:DTYMK
uniprot id: A0A8C3F417
names: Similarity
messages: Belongs to the thymidylate kinase family.

8478:LOC101943565
gene id: 8478:LOC101943565
uniprot id: A0A8C3IMY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

8478:LDAF1
gene id: 8478:LDAF1
uniprot id: A0A8C3I1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

8478:OS9
gene id: 8478:OS9
uniprot id: A0A8C3HXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

8478:CMC2
gene id: 8478:CMC2
uniprot id: A0A8C3IKV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

8478:OAF
gene id: 8478:OAF
uniprot id: A0A8C3FQL2
names: Similarity
messages: Belongs to the OAF family.

8478:STMN4
gene id: 8478:STMN4
uniprot id: A0A8C3IFL7
names: Similarity
messages: Belongs to the stathmin family.

8478:BABAM2
gene id: 8478:BABAM2
uniprot id: A0A8C3ING2
uniprot id: A0A8C3PEE5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

8478:CCNE1
gene id: 8478:CCNE1
uniprot id: A0A8C3HSV3
names: Similarity
messages: Belongs to the cyclin family.

8478:CDK18
gene id: 8478:CDK18
uniprot id: A0A8C3F1K7
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:LOC101939148
gene id: 8478:LOC101939148
uniprot id: A0A8C3HHS1
names: Similarity
messages: Belongs to the RPAP1 family.

8478:NUDT21
gene id: 8478:NUDT21
uniprot id: A0A8C3HD26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

8478:ZFPM1
gene id: 8478:ZFPM1
uniprot id: A0A8C3IGT2
names: Subcellular Location Annotation
messages: Nucleus

8478:SEC13
gene id: 8478:SEC13
uniprot id: A0A8C3HMT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

8478:MEX3C
gene id: 8478:MEX3C
uniprot id: A0A8C3INY8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8478:LOC101937540
gene id: 8478:LOC101937540
uniprot id: A0A8C3HMP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

8478:PLCB3
gene id: 8478:PLCB3
uniprot id: A0A8C3IH66
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

8478:JUN
gene id: 8478:JUN
uniprot id: A0A8C3HL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8478:DSTN
gene id: 8478:DSTN
uniprot id: A0A8C3IGJ9
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8478:KIF16B
gene id: 8478:KIF16B
uniprot id: A0A8C3IEX1
uniprot id: A0A8C3IFK0
uniprot id: A0A8C3IGF3
uniprot id: A0A8C3PCU5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8478:HEXA
gene id: 8478:HEXA
uniprot id: A0A8C3FFR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

8478:TMEM151A
gene id: 8478:TMEM151A
uniprot id: A0A8C3IF38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8478:MGA
gene id: 8478:MGA
uniprot id: A0A8C3HHL4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8478:VAPA
gene id: 8478:VAPA
uniprot id: A0A8C3J049
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:GNPAT
gene id: 8478:GNPAT
uniprot id: A0A8C3FPE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Peroxisome membrane

8478:WDFY1
gene id: 8478:WDFY1
uniprot id: A0A8C3I2G4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8478:TPM1
gene id: 8478:TPM1
uniprot id: A0A8C3HX60
uniprot id: A0A8C3HXC5
uniprot id: A0A8C3HZR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8478:MRPL50
gene id: 8478:MRPL50
uniprot id: A0A8C3FRD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

8478:PBX1
gene id: 8478:PBX1
uniprot id: A0A8C3HGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8478:ODR4
gene id: 8478:ODR4
uniprot id: A0A8C3HMK9
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

8478:FBLN7
gene id: 8478:FBLN7
uniprot id: A0A8C3FCZ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:TECPR1
gene id: 8478:TECPR1
uniprot id: A0A8C3PAK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TECPR1 family.
messages: Lysosome membrane
messages: autophagosome membrane

8478:PEX7
gene id: 8478:PEX7
uniprot id: A0A8C3HWJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

8478:GGA2
gene id: 8478:GGA2
uniprot id: A0A8C3F5W5
uniprot id: A0A8C3F958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

8478:SLC8A3
gene id: 8478:SLC8A3
uniprot id: A0A8C3ICP7
uniprot id: A0A8C3ICQ9
uniprot id: A0A8C3ICV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8478:LOC101943853
gene id: 8478:LOC101943853
uniprot id: A0A8C3HZH2
uniprot id: A0A8C3I123
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

8478:PPP1R9A
gene id: 8478:PPP1R9A
uniprot id: A0A8C3IKI1
names: Subcellular Location Annotation
messages: cytoskeleton

8478:CXCR6
gene id: 8478:CXCR6
uniprot id: A0A8C3IHG4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:CTSB
gene id: 8478:CTSB
uniprot id: A0A8C3I617
names: Similarity
messages: Belongs to the peptidase C1 family.

8478:IGFBP3
gene id: 8478:IGFBP3
uniprot id: A0A8C3HUC7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8478:SLC41A3
gene id: 8478:SLC41A3
uniprot id: A0A8C3HLA2
uniprot id: A0A8C3HLC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8478:SUSD4
gene id: 8478:SUSD4
uniprot id: A0A8C3HEF0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:HSDL1
gene id: 8478:HSDL1
uniprot id: A0A8C3HD70
uniprot id: A0A8C3HD84
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8478:GNB5
gene id: 8478:GNB5
uniprot id: A0A8C3IXY8
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8478:NIBAN1
gene id: 8478:NIBAN1
uniprot id: A0A8C3HR11
names: Similarity
messages: Belongs to the Niban family.

8478:SMARCA5
gene id: 8478:SMARCA5
uniprot id: A0A8C3IWZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

8478:TMED6
gene id: 8478:TMED6
uniprot id: A0A8C3IUQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:BID
gene id: 8478:BID
uniprot id: A0A8C3PGE3
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

8478:DNAJC24
gene id: 8478:DNAJC24
uniprot id: A0A8C3HCD5
names: Similarity
messages: Belongs to the DPH4 family.

8478:TBX15
gene id: 8478:TBX15
uniprot id: A0A8C3H5D7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8478:PSMD9
gene id: 8478:PSMD9
uniprot id: A0A8C3IQZ4
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

8478:B2M
gene id: 8478:B2M
uniprot id: A0A8C3H834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

8478:ATP1B3
gene id: 8478:ATP1B3
uniprot id: A0A8C3F5K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8478:CHD1L
gene id: 8478:CHD1L
uniprot id: A0A8C3F5Q5
uniprot id: A0A8C3FC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8478:IQSEC1
gene id: 8478:IQSEC1
uniprot id: A0A8C3I3L2
names: Similarity
messages: Belongs to the BRAG family.

8478:GPC4
gene id: 8478:GPC4
uniprot id: A0A8C3IP95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8478:LOC101934626
gene id: 8478:LOC101934626
uniprot id: A0A8C3HXH2
names: Subcellular Location Annotation
messages: Membrane

8478:MRPL49
gene id: 8478:MRPL49
uniprot id: A0A8C3IHA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

8478:POLR2H
gene id: 8478:POLR2H
uniprot id: A0A8C3F3Q9
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

8478:SLC66A1
gene id: 8478:SLC66A1
uniprot id: A0A8C3IK81
names: Subcellular Location Annotation
messages: Membrane

8478:SERPINI1
gene id: 8478:SERPINI1
uniprot id: A0A8C3HRU2
names: Similarity
messages: Belongs to the serpin family.

8478:PLCD1
gene id: 8478:PLCD1
uniprot id: A0A8C3HZG4
uniprot id: A0A8C3P9J7
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

8478:HMBOX1
gene id: 8478:HMBOX1
uniprot id: A0A8C3I4C4
uniprot id: A0A8C3I4W8
names: Subcellular Location Annotation
messages: Nucleus

8478:LOC101945056
gene id: 8478:LOC101945056
uniprot id: A0A8C3F761
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

8478:BCO2
gene id: 8478:BCO2
uniprot id: A0A8C3FPK6
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8478:QTRT2
gene id: 8478:QTRT2
uniprot id: A0A8C3F6A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

8478:MSX2
gene id: 8478:MSX2
uniprot id: A0A8C3FJT9
names: Subcellular Location Annotation
messages: Nucleus

8478:FAM189A1
gene id: 8478:FAM189A1
uniprot id: A0A8C3FVR7
uniprot id: A0A8C3G046
names: Similarity
messages: Belongs to the ENTREP family.

8478:HSPB6
gene id: 8478:HSPB6
uniprot id: A0A8C3EZU5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8478:CAPN5
gene id: 8478:CAPN5
uniprot id: A0A8C3IWP2
names: Similarity
messages: Belongs to the peptidase C2 family.

8478:MED6
gene id: 8478:MED6
uniprot id: A0A8C3IEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 6 family.
messages: Nucleus

8478:UST
gene id: 8478:UST
uniprot id: A0A8C3HVN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:GJC2
gene id: 8478:GJC2
uniprot id: A0A8C3F2H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8478:FAM168B
gene id: 8478:FAM168B
uniprot id: A0A8C3I2B6
uniprot id: A0A8C3I3L8
names: Similarity
messages: Belongs to the FAM168 family.

8478:FOXL3
gene id: 8478:FOXL3
uniprot id: A0A8C3I736
names: Subcellular Location Annotation
messages: Nucleus

8478:CLPTM1L
gene id: 8478:CLPTM1L
uniprot id: A0A8C3HSH3
uniprot id: A0A8C3P7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

8478:TTC36
gene id: 8478:TTC36
uniprot id: A0A8C3I8G8
names: Similarity
messages: Belongs to the TTC36 family.

8478:NHSL1
gene id: 8478:NHSL1
uniprot id: A0A8C3HVB9
uniprot id: A0A8C3HVC1
uniprot id: A0A8C3HVF7
uniprot id: A0A8C3HVG2
uniprot id: A0A8C3HVK0
uniprot id: A0A8C3HVX1
uniprot id: A0A8C3HXR2
names: Similarity
messages: Belongs to the NHS family.

8478:ZNF592
gene id: 8478:ZNF592
uniprot id: A0A8C3FF26
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

8478:MPPED1
gene id: 8478:MPPED1
uniprot id: A0A8C3IQ13
names: Similarity
messages: Belongs to the UPF0046 family.

8478:RBM5
gene id: 8478:RBM5
uniprot id: A0A8C3F7P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

8478:ST6GALNAC6
gene id: 8478:ST6GALNAC6
uniprot id: A0A8C3IQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8478:RECQL
gene id: 8478:RECQL
uniprot id: A0A8C3HAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

8478:SKIL
gene id: 8478:SKIL
uniprot id: A0A8C3HRG7
names: Similarity
messages: Belongs to the SKI family.

8478:SPRTN
gene id: 8478:SPRTN
uniprot id: A0A8C3FEJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

8478:GRIA3
gene id: 8478:GRIA3
uniprot id: A0A8C3HFU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8478:ISY1
gene id: 8478:ISY1
uniprot id: A0A8C3IQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

8478:RFLNA
gene id: 8478:RFLNA
uniprot id: A0A8C3PEP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8478:WNT9A
gene id: 8478:WNT9A
uniprot id: A0A8C3F1Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8478:RAD52
gene id: 8478:RAD52
uniprot id: A0A8C3IVL6
names: Similarity
messages: Belongs to the RAD52 family.

8478:LOC101949147
gene id: 8478:LOC101949147
uniprot id: A0A8C3FBT2
names: Similarity
messages: Belongs to the HMBS family.

8478:STX2
gene id: 8478:STX2
uniprot id: A0A8C3IKY1
names: Similarity
messages: Belongs to the syntaxin family.

8478:ST3GAL4
gene id: 8478:ST3GAL4
uniprot id: A0A8C3FWC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8478:KIF5B
gene id: 8478:KIF5B
uniprot id: A0A8C3HWV6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8478:PLXNA1
gene id: 8478:PLXNA1
uniprot id: A0A8C3HLR9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:NUF2
gene id: 8478:NUF2
uniprot id: A0A8C3HMG3
names: Similarity
messages: Belongs to the NUF2 family.

8478:TBCE
gene id: 8478:TBCE
uniprot id: A0A8C3FD48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

8478:LOC101942067
gene id: 8478:LOC101942067
uniprot id: A0A8C3F9T3
uniprot id: A0A8C3FBF8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

8478:TMEM229B
gene id: 8478:TMEM229B
uniprot id: A0A8C3I9F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

8478:LOC101940544
gene id: 8478:LOC101940544
uniprot id: A0A8C3I9K5
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8478:LOC101935816
gene id: 8478:LOC101935816
uniprot id: A0A8C3IA91
names: Similarity
messages: Belongs to the actin family.

8478:OLFM1
gene id: 8478:OLFM1
uniprot id: A0A8C3I7S8
uniprot id: A0A8C3I8J8
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8478:CLK1
gene id: 8478:CLK1
uniprot id: A0A8C3P2D2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:KCNK1
gene id: 8478:KCNK1
uniprot id: A0A8C3FHD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

8478:GGPS1
gene id: 8478:GGPS1
uniprot id: A0A8C3FB95
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8478:IGF1
gene id: 8478:IGF1
uniprot id: A0A8C3F176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8478:PPARG
gene id: 8478:PPARG
uniprot id: A0A8C3IU34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

8478:GNB4
gene id: 8478:GNB4
uniprot id: A0A8C3IUQ7
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8478:VIPR2
gene id: 8478:VIPR2
uniprot id: A0A8C3HV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8478:LOC101948970
gene id: 8478:LOC101948970
uniprot id: A0A8C3IYA1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8478:ATP2C1
gene id: 8478:ATP2C1
uniprot id: A0A8C3IE77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:MTFR1
gene id: 8478:MTFR1
uniprot id: A0A8C3IBK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

8478:RIN2
gene id: 8478:RIN2
uniprot id: A0A8C3IH93
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

8478:MICOS10
gene id: 8478:MICOS10
uniprot id: A0A8C3PD23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

8478:TEKT2
gene id: 8478:TEKT2
uniprot id: A0A8C3HZR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8478:DUOXA2
gene id: 8478:DUOXA2
uniprot id: A0A8C3FF87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

8478:XKRX
gene id: 8478:XKRX
uniprot id: A0A8C3HKY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8478:B3GNT4
gene id: 8478:B3GNT4
uniprot id: A0A8C3IT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:DLD
gene id: 8478:DLD
uniprot id: A0A8C3H514
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

8478:PTPN11
gene id: 8478:PTPN11
uniprot id: A0A8C3FG72
uniprot id: A0A8C3FHI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

8478:HSPA8
gene id: 8478:HSPA8
uniprot id: A0A8C3HN50
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8478:PHF19
gene id: 8478:PHF19
uniprot id: A0A8C3HDC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

8478:PRKD3
gene id: 8478:PRKD3
uniprot id: A0A8C3PD50
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

8478:VOPP1
gene id: 8478:VOPP1
uniprot id: A0A8C3IL52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8478:DUSP1
gene id: 8478:DUSP1
uniprot id: A0A8C3FRM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8478:SLC37A4
gene id: 8478:SLC37A4
uniprot id: A0A8C3FAL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8478:CDIP1
gene id: 8478:CDIP1
uniprot id: A0A8C3P2D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

8478:TMEM184C
gene id: 8478:TMEM184C
uniprot id: A0A8C3IVD5
uniprot id: A0A8C3IY41
names: Subcellular Location Annotation
messages: Membrane

8478:KIAA2013
gene id: 8478:KIAA2013
uniprot id: A0A8C3IDH9
names: Subcellular Location Annotation
messages: Membrane

8478:LOC101948044
gene id: 8478:LOC101948044
uniprot id: A0A8C3H8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8478:LOC101953652
gene id: 8478:LOC101953652
uniprot id: A0A8C3PBV9
names: Similarity
messages: Belongs to the DeSI family.

8478:SETD6
gene id: 8478:SETD6
uniprot id: A0A8C3IWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

8478:TRADD
gene id: 8478:TRADD
uniprot id: A0A8C3HD50
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

8478:TSNAX
gene id: 8478:TSNAX
uniprot id: A0A8C3H822
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

8478:THBS2
gene id: 8478:THBS2
uniprot id: A0A8C3P435
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:SNAP25
gene id: 8478:SNAP25
uniprot id: A0A8C3IGQ0
uniprot id: A0A8C3PCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

8478:ATG3
gene id: 8478:ATG3
uniprot id: A0A8C3FC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

8478:GK5
gene id: 8478:GK5
uniprot id: A0A8C3FBB1
names: Similarity
messages: Belongs to the FGGY kinase family.

8478:HMOX2
gene id: 8478:HMOX2
uniprot id: A0A8C3HCG5
names: Similarity
messages: Belongs to the heme oxygenase family.

8478:LOC101934335
gene id: 8478:LOC101934335
uniprot id: A0A8C3I0B4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

8478:YEATS2
gene id: 8478:YEATS2
uniprot id: A0A8C3PA14
uniprot id: A0A8C3PA17
names: Subcellular Location Annotation
messages: Nucleus

8478:MRPL37
gene id: 8478:MRPL37
uniprot id: A0A8C3F8T5
names: Subcellular Location Annotation
messages: Mitochondrion

8478:PPME1
gene id: 8478:PPME1
uniprot id: A0A8C3EYX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

8478:MAML1
gene id: 8478:MAML1
uniprot id: A0A8C3FQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

8478:MIEF2
gene id: 8478:MIEF2
uniprot id: A0A8C3I817
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8478:TMEM106B
gene id: 8478:TMEM106B
uniprot id: A0A8C3IIE8
names: Similarity
messages: Belongs to the TMEM106 family.

8478:NCDN
gene id: 8478:NCDN
uniprot id: A0A8C3HZX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

8478:TNFRSF21
gene id: 8478:TNFRSF21
uniprot id: A0A8C3IAW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:TCF7
gene id: 8478:TCF7
uniprot id: A0A8C3FJ99
uniprot id: A0A8C3FJD0
uniprot id: A0A8C3FKG3
uniprot id: A0A8C3FRS0
uniprot id: A0A8C3H9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8478:PATJ
gene id: 8478:PATJ
uniprot id: A0A8C3HJP9
names: Subcellular Location Annotation
messages: tight junction

8478:FABP6
gene id: 8478:FABP6
uniprot id: A0A8C3FL86
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8478:DOLK
gene id: 8478:DOLK
uniprot id: A0A8C3IF60
names: Similarity
messages: Belongs to the polyprenol kinase family.

8478:NFKB2
gene id: 8478:NFKB2
uniprot id: A0A8C3I856
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8478:LAMP2
gene id: 8478:LAMP2
uniprot id: A0A8C3HFZ5
uniprot id: A0A8C3P4Q9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

8478:LOC101944606
gene id: 8478:LOC101944606
uniprot id: A0A8C3IYP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:FLI1
gene id: 8478:FLI1
uniprot id: A0A8C3IUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8478:TUBA8
gene id: 8478:TUBA8
uniprot id: A0A8C3IYZ8
uniprot id: A0A8C3PGH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8478:CMAS
gene id: 8478:CMAS
uniprot id: A0A8C3FPB9
names: Similarity
messages: Belongs to the CMP-NeuNAc synthase family.

8478:TXNL4B
gene id: 8478:TXNL4B
uniprot id: A0A8C3FF77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

8478:HHATL
gene id: 8478:HHATL
uniprot id: A0A8C3FE26
names: Subcellular Location Annotation
messages: Membrane

8478:RAB18
gene id: 8478:RAB18
uniprot id: A0A8C3HR16
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

8478:ETS1
gene id: 8478:ETS1
uniprot id: A0A8C3FWU2
uniprot id: A0A8C3FYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

8478:RPS6KA4
gene id: 8478:RPS6KA4
uniprot id: A0A8C3IGF2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8478:TNS3
gene id: 8478:TNS3
uniprot id: A0A8C3HUC3
uniprot id: A0A8C3P896
uniprot id: A0A8C3P8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

8478:JAG1
gene id: 8478:JAG1
uniprot id: A0A8C3PCW2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8478:URM1
gene id: 8478:URM1
uniprot id: A0A8C3PE57
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Cytoplasm

8478:LOC101938934
gene id: 8478:LOC101938934
uniprot id: A0A8C3F1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

8478:LOC101941081
gene id: 8478:LOC101941081
uniprot id: A0A8C3J334
names: Similarity
messages: Belongs to the perilipin family.

8478:HSD17B12
gene id: 8478:HSD17B12
uniprot id: A0A8C3HEX7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8478:LOC101935783
gene id: 8478:LOC101935783
uniprot id: A0A8C3I0R9
names: Similarity
messages: Belongs to the ARTD/PARP family.

8478:MAGOH
gene id: 8478:MAGOH
uniprot id: A0A8C3EYM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

8478:SLC39A13
gene id: 8478:SLC39A13
uniprot id: A0A8C3IGT8
names: Subcellular Location Annotation
messages: Membrane

8478:TM7SF3
gene id: 8478:TM7SF3
uniprot id: A0A8C3IFT9
names: Subcellular Location Annotation
messages: Membrane

8478:MPC2
gene id: 8478:MPC2
uniprot id: A0A8C3FE76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8478:ANAPC10
gene id: 8478:ANAPC10
uniprot id: A0A8C3IVZ4
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

8478:KCNK7
gene id: 8478:KCNK7
uniprot id: A0A8C3II68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

8478:LOC101941418
gene id: 8478:LOC101941418
uniprot id: A0A8C3IJU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8478:GPAT4
gene id: 8478:GPAT4
uniprot id: A0A8C3H6M8
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8478:SCG3
gene id: 8478:SCG3
uniprot id: A0A8C3IW01
uniprot id: A0A8C3PG47
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

8478:CHRDL1
gene id: 8478:CHRDL1
uniprot id: A0A8C3EZ07
names: Subcellular Location Annotation
messages: Secreted

8478:TPPP3
gene id: 8478:TPPP3
uniprot id: A0A8C3HLV5
names: Similarity
messages: Belongs to the TPPP family.

8478:LOC101953854
gene id: 8478:LOC101953854
uniprot id: A0A8C3FYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

8478:LOC101945370
gene id: 8478:LOC101945370
uniprot id: A0A8C3HUW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

8478:SERPINH1
gene id: 8478:SERPINH1
uniprot id: A0A8C3IVB8
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

8478:TMC7
gene id: 8478:TMC7
uniprot id: A0A8C3FYZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8478:RPL6
gene id: 8478:RPL6
uniprot id: A0A8C3FHH2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

8478:IWS1
gene id: 8478:IWS1
uniprot id: A0A8C3HYJ0
uniprot id: A0A8C3P9E2
names: Subcellular Location Annotation
messages: Nucleus

8478:LTV1
gene id: 8478:LTV1
uniprot id: A0A8C3HVE4
names: Similarity
messages: Belongs to the LTV1 family.

8478:TULP3
gene id: 8478:TULP3
uniprot id: A0A8C3HAV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

8478:ZBED4
gene id: 8478:ZBED4
uniprot id: A0A8C3IBE3
names: Subcellular Location Annotation
messages: Nucleus

8478:PHAF1
gene id: 8478:PHAF1
uniprot id: A0A8C3P2Y2
names: Similarity
messages: Belongs to the PHAF1 family.

8478:PCYOX1L
gene id: 8478:PCYOX1L
uniprot id: A0A8C3FLF4
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

8478:PHGDH
gene id: 8478:PHGDH
uniprot id: A0A8C3F8S9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8478:RBM48
gene id: 8478:RBM48
uniprot id: A0A8C3PDT9
names: Function
names: Similarity
messages: As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
messages: Belongs to the RBM48 family.

8478:FOXB1
gene id: 8478:FOXB1
uniprot id: A0A8C3HVD4
names: Subcellular Location Annotation
messages: Nucleus

8478:TBC1D23
gene id: 8478:TBC1D23
uniprot id: A0A8C3F8P5
names: Subcellular Location Annotation
messages: trans-Golgi network

8478:MGST1
gene id: 8478:MGST1
uniprot id: A0A8C3PGH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

8478:ZDHHC7
gene id: 8478:ZDHHC7
uniprot id: A0A8C3IH57
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:TMEM178B
gene id: 8478:TMEM178B
uniprot id: A0A8C3P2F9
names: Similarity
messages: Belongs to the TMEM178 family.

8478:HAUS1
gene id: 8478:HAUS1
uniprot id: A0A8C3PEJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

8478:IRX1
gene id: 8478:IRX1
uniprot id: A0A8C3EYH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8478:ALOX5
gene id: 8478:ALOX5
uniprot id: A0A8C3H828
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:RAPSN
gene id: 8478:RAPSN
uniprot id: A0A8C3IEH3
names: Similarity
messages: Belongs to the RAPsyn family.

8478:MFF
gene id: 8478:MFF
uniprot id: A0A8C3I355
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

8478:RPL32
gene id: 8478:RPL32
uniprot id: A0A8C3HMR6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

8478:TASP1
gene id: 8478:TASP1
uniprot id: A0A8C3IGK6
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8478:TXLNB
gene id: 8478:TXLNB
uniprot id: A0A8C3P8P8
names: Similarity
messages: Belongs to the taxilin family.

8478:PKNOX2
gene id: 8478:PKNOX2
uniprot id: A0A8C3HBH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8478:PIGC
gene id: 8478:PIGC
uniprot id: A0A8C3FBJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

8478:FLCN
gene id: 8478:FLCN
uniprot id: A0A8C3PB87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

8478:KLHL40
gene id: 8478:KLHL40
uniprot id: A0A8C3FAC3
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

8478:LOC101948238
gene id: 8478:LOC101948238
uniprot id: A0A8C3HF44
names: Subcellular Location Annotation
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8478:CTNNB1
gene id: 8478:CTNNB1
uniprot id: A0A8C3IGE4
names: Similarity
messages: Belongs to the beta-catenin family.

8478:SMYD2
gene id: 8478:SMYD2
uniprot id: A0A8C3HGP6
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
messages: cytosol

8478:NAMPT
gene id: 8478:NAMPT
uniprot id: A0A8C3F7X7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

8478:SLC41A1
gene id: 8478:SLC41A1
uniprot id: A0A8C3F283
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8478:NADSYN1
gene id: 8478:NADSYN1
uniprot id: A0A8C3HL67
uniprot id: A0A8C3P6L1
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

8478:NFRKB
gene id: 8478:NFRKB
uniprot id: A0A8C3ITI5
names: Subcellular Location Annotation
messages: Nucleus

8478:RAB33B
gene id: 8478:RAB33B
uniprot id: A0A8C3IWE2
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8478:ZER1
gene id: 8478:ZER1
uniprot id: A0A8C3IGU4
names: Similarity
messages: Belongs to the zyg-11 family.

8478:SFPQ
gene id: 8478:SFPQ
uniprot id: A0A8C3I052
names: Subcellular Location Annotation
messages: Nucleus speckle

8478:GPC1
gene id: 8478:GPC1
uniprot id: A0A8C3I3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8478:NKRF
gene id: 8478:NKRF
uniprot id: A0A8C3I7N6
names: Similarity
messages: Belongs to the CARF family.

8478:PSEN1
gene id: 8478:PSEN1
uniprot id: A0A8C3HBL8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

8478:NSUN3
gene id: 8478:NSUN3
uniprot id: A0A8C3FDN7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8478:NFIB
gene id: 8478:NFIB
uniprot id: A0A8C3INX3
uniprot id: A0A8C3IQP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

8478:KCNK4
gene id: 8478:KCNK4
uniprot id: A0A8C3IFJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8478:DDX58
gene id: 8478:DDX58
uniprot id: A0A8C3FLU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

8478:SDE2
gene id: 8478:SDE2
uniprot id: A0A8C3HD16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Cytoplasm
messages: Nucleus

8478:CDH11
gene id: 8478:CDH11
uniprot id: A0A8C3HCS9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8478:ATP2B4
gene id: 8478:ATP2B4
uniprot id: A0A8C3HW09
uniprot id: A0A8C3HWE2
uniprot id: A0A8C3P8U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:EARS2
gene id: 8478:EARS2
uniprot id: A0A8C3F499
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

8478:LOC101942851
gene id: 8478:LOC101942851
uniprot id: A0A8C3IMT2
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

8478:RAB27B
gene id: 8478:RAB27B
uniprot id: A0A8C3INW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8478:ATP6V1D
gene id: 8478:ATP6V1D
uniprot id: A0A8C3FG45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

8478:SNRPD1
gene id: 8478:SNRPD1
uniprot id: A0A8C3IFX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

8478:TRPM2
gene id: 8478:TRPM2
uniprot id: A0A8C3EZJ6
uniprot id: A0A8C3F1U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

8478:FGD4
gene id: 8478:FGD4
uniprot id: A0A8C3I5V1
uniprot id: A0A8C3I5X5
uniprot id: A0A8C3I6J9
names: Subcellular Location Annotation
messages: cytoskeleton

8478:LOC101935285
gene id: 8478:LOC101935285
uniprot id: A0A8C3F2F6
names: Similarity
messages: Belongs to the AccD/PCCB family.

8478:JAK1
gene id: 8478:JAK1
uniprot id: A0A8C3F0V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

8478:LOC101938767
gene id: 8478:LOC101938767
uniprot id: A0A8C3I199
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8478:TYRO3
gene id: 8478:TYRO3
uniprot id: A0A8C3HHT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

8478:MTMR1
gene id: 8478:MTMR1
uniprot id: A0A8C3I765
uniprot id: A0A8C3I7B6
uniprot id: A0A8C3I816
uniprot id: A0A8C3IAE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8478:RFC4
gene id: 8478:RFC4
uniprot id: A0A8C3F0X3
names: Similarity
messages: Belongs to the activator 1 small subunits family.

8478:PROK2
gene id: 8478:PROK2
uniprot id: A0A8C3FFI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

8478:CD82
gene id: 8478:CD82
uniprot id: A0A8C3HEY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:RAD18
gene id: 8478:RAD18
uniprot id: A0A8C3HMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

8478:CORO1C
gene id: 8478:CORO1C
uniprot id: A0A8C3FGP1
names: Similarity
messages: Belongs to the WD repeat coronin family.

8478:LOC101950447
gene id: 8478:LOC101950447
uniprot id: A0A8C3FN32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8478:TLX3
gene id: 8478:TLX3
uniprot id: A0A8C3IBS9
names: Subcellular Location Annotation
messages: Nucleus

8478:KDELR2
gene id: 8478:KDELR2
uniprot id: A0A8C3I2Z9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:LOC101944630
gene id: 8478:LOC101944630
uniprot id: A0A8C3HM84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:LOC101951251
gene id: 8478:LOC101951251
uniprot id: A0A8C3ILK6
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

8478:PEX1
gene id: 8478:PEX1
uniprot id: A0A8C3IL75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: cytosol

8478:PRKCI
gene id: 8478:PRKCI
uniprot id: A0A8C3HRG0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8478:HOATZ
gene id: 8478:HOATZ
uniprot id: A0A8C3FNZ2
names: Similarity
messages: Belongs to the HOATZ family.

8478:PGM1
gene id: 8478:PGM1
uniprot id: A0A8C3HKM5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8478:ING3
gene id: 8478:ING3
uniprot id: A0A8C3FTR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8478:CDCA8
gene id: 8478:CDCA8
uniprot id: A0A8C3P9J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

8478:RDH10
gene id: 8478:RDH10
uniprot id: A0A8C3FH88
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8478:LOC101947545
gene id: 8478:LOC101947545
uniprot id: A0A8C3HNX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:OXTR
gene id: 8478:OXTR
uniprot id: A0A8C3HN01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8478:LOC101952050
gene id: 8478:LOC101952050
uniprot id: A0A8C3IBI7
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

8478:PLD1
gene id: 8478:PLD1
uniprot id: A0A8C3HR81
uniprot id: A0A8C3HR99
names: Similarity
messages: Belongs to the phospholipase D family.

8478:ATG13
gene id: 8478:ATG13
uniprot id: A0A8C3HF93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

8478:CAPN11
gene id: 8478:CAPN11
uniprot id: A0A8C3ILS6
names: Similarity
messages: Belongs to the peptidase C2 family.

8478:RNF146
gene id: 8478:RNF146
uniprot id: A0A8C3HZQ8
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

8478:RPL7A
gene id: 8478:RPL7A
uniprot id: A0A8C3I8I4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

8478:CDK9
gene id: 8478:CDK9
uniprot id: A0A8C3IMG6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:WDR12
gene id: 8478:WDR12
uniprot id: A0A8C3FWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

8478:YWHAQ
gene id: 8478:YWHAQ
uniprot id: A0A8C3HKI7
names: Similarity
messages: Belongs to the 14-3-3 family.

8478:POPDC2
gene id: 8478:POPDC2
uniprot id: A0A8C3F3Y0
uniprot id: A0A8C3F7C1
names: Similarity
messages: Belongs to the popeye family.

8478:SLC35F4
gene id: 8478:SLC35F4
uniprot id: A0A8C3IPQ2
uniprot id: A0A8C3PDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

8478:STX19
gene id: 8478:STX19
uniprot id: A0A8C3FDE8
names: Similarity
messages: Belongs to the syntaxin family.

8478:C3H6orf120
gene id: 8478:C3H6orf120
uniprot id: A0A8C3HEN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

8478:NDUFV2
gene id: 8478:NDUFV2
uniprot id: A0A8C3IZ42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

8478:HMGN3
gene id: 8478:HMGN3
uniprot id: A0A8C3IF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

8478:OTX2
gene id: 8478:OTX2
uniprot id: A0A8C3PDW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8478:COG2
gene id: 8478:COG2
uniprot id: A0A8C3FIF9
names: Similarity
messages: Belongs to the COG2 family.

8478:POLR1C
gene id: 8478:POLR1C
uniprot id: A0A8C3IMR9
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

8478:C1H11orf87
gene id: 8478:C1H11orf87
uniprot id: A0A8C3I0E9
names: Subcellular Location Annotation
messages: Membrane

8478:PEX14
gene id: 8478:PEX14
uniprot id: A0A8C3PBZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
messages: Peroxisome membrane

8478:CYRIA
gene id: 8478:CYRIA
uniprot id: A0A8C3HHD5
uniprot id: A0A8C3HHE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

8478:ARPP19
gene id: 8478:ARPP19
uniprot id: A0A8C3IY48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

8478:LOC101941898
gene id: 8478:LOC101941898
uniprot id: A0A8C3IKH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8478:RAN
gene id: 8478:RAN
uniprot id: A0A8C3IK50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

8478:GABRB1
gene id: 8478:GABRB1
uniprot id: A0A8C3IXQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8478:ADCY1
gene id: 8478:ADCY1
uniprot id: A0A8C3P8B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8478:LDHB
gene id: 8478:LDHB
uniprot id: A0A8C3FUB3
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

8478:CCNG1
gene id: 8478:CCNG1
uniprot id: A0A8C3FKT5
names: Similarity
messages: Belongs to the cyclin family.

8478:PAX6
gene id: 8478:PAX6
uniprot id: A0A8C3HCH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8478:MDGA1
gene id: 8478:MDGA1
uniprot id: A0A8C3INS8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8478:TFAP2E
gene id: 8478:TFAP2E
uniprot id: A0A8C3I2N8
names: Similarity
messages: Belongs to the AP-2 family.

8478:CRYBB2
gene id: 8478:CRYBB2
uniprot id: A0A8C3PBN3
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

8478:RBBP5
gene id: 8478:RBBP5
uniprot id: A0A8C3F3N9
names: Subcellular Location Annotation
messages: Nucleus

8478:KCNF1
gene id: 8478:KCNF1
uniprot id: A0A8C3HK29
names: Subcellular Location Annotation
messages: Membrane

8478:AR
gene id: 8478:AR
uniprot id: A0A8C3FI18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8478:CMTM4
gene id: 8478:CMTM4
uniprot id: A0A8C3HDB8
names: Subcellular Location Annotation
messages: Membrane

8478:TAF13
gene id: 8478:TAF13
uniprot id: A0A8C3FA20
names: Subcellular Location Annotation
messages: Nucleus

8478:SEC24A
gene id: 8478:SEC24A
uniprot id: A0A8C3FMM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8478:LOC101950316
gene id: 8478:LOC101950316
uniprot id: A0A8C3I1G6
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8478:C18H1orf174
gene id: 8478:C18H1orf174
uniprot id: A0A8C3I4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

8478:PRR5L
gene id: 8478:PRR5L
uniprot id: A0A8C3HEW4
names: Similarity
messages: Belongs to the PROTOR family.

8478:CRBN
gene id: 8478:CRBN
uniprot id: A0A8C3HWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

8478:LOC101949762
gene id: 8478:LOC101949762
uniprot id: A0A8C3PE67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

8478:ZDHHC4
gene id: 8478:ZDHHC4
uniprot id: A0A8C3F911
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:DMRT3
gene id: 8478:DMRT3
uniprot id: A0A8C3INC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8478:LOC101940001
gene id: 8478:LOC101940001
uniprot id: A0A8C3IXB0
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8478:P4HA2
gene id: 8478:P4HA2
uniprot id: A0A8C3IPK9
uniprot id: A0A8C3IPV1
uniprot id: A0A8C3PE37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

8478:PIK3C3
gene id: 8478:PIK3C3
uniprot id: A0A8C3FHF4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8478:HTR6
gene id: 8478:HTR6
uniprot id: A0A8C3IGM9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:OGFRL1
gene id: 8478:OGFRL1
uniprot id: A0A8C3HY70
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

8478:MDM4
gene id: 8478:MDM4
uniprot id: A0A8C3F1I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

8478:TSPO
gene id: 8478:TSPO
uniprot id: A0A8C3IQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

8478:HDX
gene id: 8478:HDX
uniprot id: A0A8C3P6V9
names: Subcellular Location Annotation
messages: Nucleus

8478:CAV1
gene id: 8478:CAV1
uniprot id: A0A8C3FJ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8478:RUNX2
gene id: 8478:RUNX2
uniprot id: A0A8C3PBQ5
names: Subcellular Location Annotation
messages: Nucleus

8478:CEL
gene id: 8478:CEL
uniprot id: A0A8C3I8E9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8478:MGAT5
gene id: 8478:MGAT5
uniprot id: A0A8C3FSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

8478:CCNY
gene id: 8478:CCNY
uniprot id: A0A8C3P8L1
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8478:COPG1
gene id: 8478:COPG1
uniprot id: A0A8C3HL32
uniprot id: A0A8C3P6S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

8478:NRP1
gene id: 8478:NRP1
uniprot id: A0A8C3P8K4
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:DGAT2
gene id: 8478:DGAT2
uniprot id: A0A8C3IXD9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:NCF2
gene id: 8478:NCF2
uniprot id: A0A8C3HR46
uniprot id: A0A8C3HRD9
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

8478:TENT5D
gene id: 8478:TENT5D
uniprot id: A0A8C3HM17
names: Similarity
messages: Belongs to the TENT family.

8478:LOC101935140
gene id: 8478:LOC101935140
uniprot id: A0A8C3IV40
names: Subcellular Location Annotation
messages: acrosome

8478:TAFA3
gene id: 8478:TAFA3
uniprot id: A0A8C3P9K0
names: Similarity
messages: Belongs to the TAFA family.

8478:MALL
gene id: 8478:MALL
uniprot id: A0A8C3IGJ1
names: Subcellular Location Annotation
messages: Membrane

8478:CMC1
gene id: 8478:CMC1
uniprot id: A0A8C3IEG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

8478:LOC101930758
gene id: 8478:LOC101930758
uniprot id: A0A8C3HCT5
names: Similarity
messages: Belongs to the peptidase M14 family.

8478:APLP1
gene id: 8478:APLP1
uniprot id: A0A8C3F119
uniprot id: A0A8C3F3P5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8478:DHX9
gene id: 8478:DHX9
uniprot id: A0A8C3HRC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

8478:CPSF3
gene id: 8478:CPSF3
uniprot id: A0A8C3P6K8
names: Subcellular Location Annotation
messages: Nucleus

8478:TANGO6
gene id: 8478:TANGO6
uniprot id: A0A8C3PFJ4
names: Similarity
messages: Belongs to the Tango6 family.

8478:WASL
gene id: 8478:WASL
uniprot id: A0A8C3I7Y6
names: Subcellular Location Annotation
messages: Nucleus

8478:LOC101931260
gene id: 8478:LOC101931260
uniprot id: A0A8C3HDC1
names: Subcellular Location Annotation
messages: Membrane

8478:CAV2
gene id: 8478:CAV2
uniprot id: A0A8C3FN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: caveola

8478:CSRNP1
gene id: 8478:CSRNP1
uniprot id: A0A8C3I1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8478:GUCY1A2
gene id: 8478:GUCY1A2
uniprot id: A0A8C3EYT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

8478:MOGAT2
gene id: 8478:MOGAT2
uniprot id: A0A8C3IX23
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:ABCD2
gene id: 8478:ABCD2
uniprot id: A0A8C3FU50
names: Subcellular Location Annotation
messages: Membrane

8478:ACTR10
gene id: 8478:ACTR10
uniprot id: A0A8C3INJ8
names: Similarity
messages: Belongs to the actin family.

8478:PHF10
gene id: 8478:PHF10
uniprot id: A0A8C3HEV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

8478:PPIL3
gene id: 8478:PPIL3
uniprot id: A0A8C3HCE2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8478:DHCR7
gene id: 8478:DHCR7
uniprot id: A0A8C3HKK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

8478:IL5RA
gene id: 8478:IL5RA
uniprot id: A0A8C3P906
names: Subcellular Location Annotation
messages: Membrane

8478:SEC24C
gene id: 8478:SEC24C
uniprot id: A0A8C3I7Q1
uniprot id: A0A8C3PB28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8478:LOC101946450
gene id: 8478:LOC101946450
uniprot id: A0A8C3FUD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:LOC101937164
gene id: 8478:LOC101937164
uniprot id: A0A8C3HRT3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:LOC101943570
gene id: 8478:LOC101943570
uniprot id: A0A8C3IF33
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

8478:ADCY3
gene id: 8478:ADCY3
uniprot id: A0A8C3IC76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8478:PKIA
gene id: 8478:PKIA
uniprot id: A0A8C3FHT5
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

8478:TSPAN2
gene id: 8478:TSPAN2
uniprot id: A0A8C3HW47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:LOC101941680
gene id: 8478:LOC101941680
uniprot id: A0A8C3IL48
names: Similarity
messages: Belongs to the cytochrome P450 family.

8478:B3GNT5
gene id: 8478:B3GNT5
uniprot id: A0A8C3F0E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:PSMD5
gene id: 8478:PSMD5
uniprot id: A0A8C3HDD8
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

8478:RTN3
gene id: 8478:RTN3
uniprot id: A0A8C3IGG6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:FECH
gene id: 8478:FECH
uniprot id: A0A8C3IP34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

8478:ZDHHC13
gene id: 8478:ZDHHC13
uniprot id: A0A8C3HKN5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:RAD50
gene id: 8478:RAD50
uniprot id: A0A8C3HT07
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

8478:YIPF4
gene id: 8478:YIPF4
uniprot id: A0A8C3IKC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:GPR119
gene id: 8478:GPR119
uniprot id: A0A8C3HDE5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:MAP7
gene id: 8478:MAP7
uniprot id: A0A8C3HWI3
uniprot id: A0A8C3HWM8
names: Similarity
messages: Belongs to the MAP7 family.

8478:SCAI
gene id: 8478:SCAI
uniprot id: A0A8C3IX07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAI family.
messages: Cytoplasm
messages: Interacts with DIAPH1. Forms a nuclear ternary complex with MRTFA and SRF.
messages: Nucleus
messages: Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.

8478:RRP15
gene id: 8478:RRP15
uniprot id: A0A8C3P502
names: Similarity
messages: Belongs to the RRP15 family.

8478:ECRG4
gene id: 8478:ECRG4
uniprot id: A0A8C3FHS3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

8478:ZNF277
gene id: 8478:ZNF277
uniprot id: A0A8C3IS55
uniprot id: A0A8C3IU38
names: Similarity
messages: Belongs to the ZNF277 family.

8478:TRIP13
gene id: 8478:TRIP13
uniprot id: A0A8C3F1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

8478:DDB2
gene id: 8478:DDB2
uniprot id: A0A8C3HPQ4
uniprot id: A0A8C3HPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

8478:MAB21L2
gene id: 8478:MAB21L2
uniprot id: A0A8C3IZE4
names: Similarity
messages: Belongs to the mab-21 family.

8478:PSD
gene id: 8478:PSD
uniprot id: A0A8C3I6W7
names: Subcellular Location Annotation
messages: ruffle membrane

8478:LOC101950129
gene id: 8478:LOC101950129
uniprot id: A0A8C3ITK8
uniprot id: A0A8C3IW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8478:LOC101940914
gene id: 8478:LOC101940914
uniprot id: A0A8C3PDA5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

8478:SEC31B
gene id: 8478:SEC31B
uniprot id: A0A8C3I6B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

8478:ARG1
gene id: 8478:ARG1
uniprot id: A0A8C3HZA9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

8478:MAN1A1
gene id: 8478:MAN1A1
uniprot id: A0A8C3P9Q1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8478:AIF1L
gene id: 8478:AIF1L
uniprot id: A0A8C3IDH2
names: Subcellular Location Annotation
messages: ruffle membrane

8478:PLA2G4F
gene id: 8478:PLA2G4F
uniprot id: A0A8C3HBN1
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

8478:LOC101940477
gene id: 8478:LOC101940477
uniprot id: A0A8C3I8A1
names: Subcellular Location Annotation
messages: Membrane

8478:YIF1A
gene id: 8478:YIF1A
uniprot id: A0A8C3ICR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

8478:LOC101933341
gene id: 8478:LOC101933341
uniprot id: A0A8C3I7D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

8478:ATR
gene id: 8478:ATR
uniprot id: A0A8C3HA86
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

8478:SSBP3
gene id: 8478:SSBP3
uniprot id: A0A8C3F8V3
names: Subcellular Location Annotation
messages: Nucleus

8478:SH3YL1
gene id: 8478:SH3YL1
uniprot id: A0A8C3IBH6
names: Similarity
messages: Belongs to the SH3YL1 family.

8478:SNX8
gene id: 8478:SNX8
uniprot id: A0A8C3I9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8478:MRPL14
gene id: 8478:MRPL14
uniprot id: A0A8C3ILP7
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

8478:ANXA6
gene id: 8478:ANXA6
uniprot id: A0A8C3FUC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

8478:LOC101938931
gene id: 8478:LOC101938931
uniprot id: A0A8C3IFS9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:SLC13A4
gene id: 8478:SLC13A4
uniprot id: A0A8C3FXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8478:RELA
gene id: 8478:RELA
uniprot id: A0A8C3IFD7
names: Subcellular Location Annotation
messages: Nucleus

8478:ATP1B4
gene id: 8478:ATP1B4
uniprot id: A0A8C3HFY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8478:FAM102A
gene id: 8478:FAM102A
uniprot id: A0A8C3IRA8
names: Similarity
messages: Belongs to the EEIG family.

8478:FAM214A
gene id: 8478:FAM214A
uniprot id: A0A8C3IYK1
uniprot id: A0A8C3PGE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

8478:LOC101952719
gene id: 8478:LOC101952719
uniprot id: A0A8C3EXY3
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8478:APH1B
gene id: 8478:APH1B
uniprot id: A0A8C3HX53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

8478:STXBP5L
gene id: 8478:STXBP5L
uniprot id: A0A8C3F3F9
uniprot id: A0A8C3F3Z8
uniprot id: A0A8C3H5P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8478:TMEM151B
gene id: 8478:TMEM151B
uniprot id: A0A8C3IN72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8478:GDPD2
gene id: 8478:GDPD2
uniprot id: A0A8C3P8E0
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8478:TOM1L2
gene id: 8478:TOM1L2
uniprot id: A0A8C3I8N9
uniprot id: A0A8C3IA12
uniprot id: A0A8C3IAY2
uniprot id: A0A8C3PB86
names: Similarity
messages: Belongs to the TOM1 family.

8478:LOC101935126
gene id: 8478:LOC101935126
uniprot id: A0A8C3I3Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8478:LOC101935599
gene id: 8478:LOC101935599
uniprot id: A0A8C3INY6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

8478:BLOC1S2
gene id: 8478:BLOC1S2
uniprot id: A0A8C3I7D0
names: Similarity
messages: Belongs to the BLOC1S2 family.

8478:DGKB
gene id: 8478:DGKB
uniprot id: A0A8C3IAM5
uniprot id: A0A8C3IBK2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8478:MOXD1
gene id: 8478:MOXD1
uniprot id: A0A8C3HYH0
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

8478:CHRM4
gene id: 8478:CHRM4
uniprot id: A0A8C3HFA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8478:ARL6IP5
gene id: 8478:ARL6IP5
uniprot id: A0A8C3EY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8478:TIPRL
gene id: 8478:TIPRL
uniprot id: A0A8C3F814
names: Similarity
messages: Belongs to the TIP41 family.

8478:GPR157
gene id: 8478:GPR157
uniprot id: A0A8C3ICI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 5 family.
messages: Membrane

8478:MAP6
gene id: 8478:MAP6
uniprot id: A0A8C3PG33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

8478:BANF2
gene id: 8478:BANF2
uniprot id: A0A8C3IH37
names: Subcellular Location Annotation
messages: Nucleus

8478:PDIA6
gene id: 8478:PDIA6
uniprot id: A0A8C3HK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

8478:GATA2
gene id: 8478:GATA2
uniprot id: A0A8C3HL60
names: Subcellular Location Annotation
messages: Nucleus

8478:SSTR4
gene id: 8478:SSTR4
uniprot id: A0A8C3IH06
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:POLR2G
gene id: 8478:POLR2G
uniprot id: A0A8C3HXN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

8478:SOX14
gene id: 8478:SOX14
uniprot id: A0A8C3F6A2
names: Subcellular Location Annotation
messages: Nucleus

8478:BRINP2
gene id: 8478:BRINP2
uniprot id: A0A8C3HLP8
names: Similarity
messages: Belongs to the BRINP family.

8478:SEC16A
gene id: 8478:SEC16A
uniprot id: A0A8C3HDT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

8478:LOC101941295
gene id: 8478:LOC101941295
uniprot id: A0A8C3IBS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

8478:TRNT1
gene id: 8478:TRNT1
uniprot id: A0A8C3HXC9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

8478:MMP16
gene id: 8478:MMP16
uniprot id: A0A8C3FQE8
uniprot id: A0A8C3FV64
uniprot id: A0A8C3FXV4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8478:DLL4
gene id: 8478:DLL4
uniprot id: A0A8C3HI54
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8478:TFIP11
gene id: 8478:TFIP11
uniprot id: A0A8C3IA07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
messages: Nucleus

8478:VWC2
gene id: 8478:VWC2
uniprot id: A0A8C3HTK8
names: Subcellular Location Annotation
messages: Synapse

8478:LOC103306399
gene id: 8478:LOC103306399
uniprot id: A0A8C3IAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

8478:BYSL
gene id: 8478:BYSL
uniprot id: A0A8C3HX42
names: Similarity
messages: Belongs to the bystin family.

8478:GPR31
gene id: 8478:GPR31
uniprot id: A0A8C3HEW7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:LOC101945157
gene id: 8478:LOC101945157
uniprot id: A0A8C3I5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8478:GRB10
gene id: 8478:GRB10
uniprot id: A0A8C3HSW8
uniprot id: A0A8C3HT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

8478:LOC101938983
gene id: 8478:LOC101938983
uniprot id: A0A8C3IAQ6
names: Subcellular Location Annotation
messages: Membrane

8478:ISCU
gene id: 8478:ISCU
uniprot id: A0A8C3FGH6
names: Similarity
messages: Belongs to the NifU family.

8478:CAPN6
gene id: 8478:CAPN6
uniprot id: A0A8C3F1R4
names: Similarity
messages: Belongs to the peptidase C2 family.

8478:SDHA
gene id: 8478:SDHA
uniprot id: A0A8C3F0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

8478:METTL26
gene id: 8478:METTL26
uniprot id: A0A8C3IKQ9
names: Similarity
messages: Belongs to the UPF0585 family.

8478:DTD1
gene id: 8478:DTD1
uniprot id: A0A8C3IJW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

8478:TSPAN19
gene id: 8478:TSPAN19
uniprot id: A0A8C3F582
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:STK38
gene id: 8478:STK38
uniprot id: A0A8C3IRG0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:MYO1E
gene id: 8478:MYO1E
uniprot id: A0A8C3FV92
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8478:SF3B1
gene id: 8478:SF3B1
uniprot id: A0A8C3IAY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

8478:CDA
gene id: 8478:CDA
uniprot id: A0A8C3IKG4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

8478:CPNE8
gene id: 8478:CPNE8
uniprot id: A0A8C3HBZ5
names: Similarity
messages: Belongs to the copine family.

8478:RNF8
gene id: 8478:RNF8
uniprot id: A0A8C3IQB6
names: Similarity
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.

8478:LOC101949686
gene id: 8478:LOC101949686
uniprot id: A0A8C3ICN9
names: Similarity
messages: Belongs to the actin family.

8478:RPL24
gene id: 8478:RPL24
uniprot id: A0A8C3FA65
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

8478:KCNA4
gene id: 8478:KCNA4
uniprot id: A0A8C3P241
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

8478:GAB1
gene id: 8478:GAB1
uniprot id: A0A8C3IW10
uniprot id: A0A8C3IWH8
uniprot id: A0A8C3J066
names: Similarity
messages: Belongs to the GAB family.

8478:RAB14
gene id: 8478:RAB14
uniprot id: A0A8C3FSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

8478:RIOX2
gene id: 8478:RIOX2
uniprot id: A0A8C3FFA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

8478:GRM1
gene id: 8478:GRM1
uniprot id: A0A8C3HTS5
uniprot id: A0A8C3HUF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8478:MRPS5
gene id: 8478:MRPS5
uniprot id: A0A8C3P9D7
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

8478:CCND1
gene id: 8478:CCND1
uniprot id: A0A8C3HCL4
names: Similarity
messages: Belongs to the cyclin family.

8478:MYOZ1
gene id: 8478:MYOZ1
uniprot id: A0A8C3I6H7
names: Similarity
messages: Belongs to the myozenin family.

8478:CREBL2
gene id: 8478:CREBL2
uniprot id: A0A8C3F1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

8478:OSBPL3
gene id: 8478:OSBPL3
uniprot id: A0A8C3ICZ6
uniprot id: A0A8C3IFF7
names: Similarity
messages: Belongs to the OSBP family.

8478:LOC101934137
gene id: 8478:LOC101934137
uniprot id: A0A8C3F8U7
uniprot id: A0A8C3H5X2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:SERPINE2
gene id: 8478:SERPINE2
uniprot id: A0A8C3PA59
names: Similarity
messages: Belongs to the serpin family.

8478:CCN2
gene id: 8478:CCN2
uniprot id: A0A8C3P940
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8478:TIGD4
gene id: 8478:TIGD4
uniprot id: A0A8C3PEL1
names: Subcellular Location Annotation
messages: Nucleus

8478:ERGIC2
gene id: 8478:ERGIC2
uniprot id: A0A8C3FYE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8478:PPP1CC
gene id: 8478:PPP1CC
uniprot id: A0A8C3F8D3
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

8478:C15H16orf87
gene id: 8478:C15H16orf87
uniprot id: A0A8C3HTP3
names: Similarity
messages: Belongs to the UPF0547 family.

8478:DHX30
gene id: 8478:DHX30
uniprot id: A0A8C3HPH1
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

8478:POU4F2
gene id: 8478:POU4F2
uniprot id: A0A8C3IWJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8478:LOC101952652
gene id: 8478:LOC101952652
uniprot id: A0A8C3HRL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

8478:HOXA2
gene id: 8478:HOXA2
uniprot id: A0A8C3IFB0
names: Subcellular Location Annotation
messages: Nucleus

8478:STX5
gene id: 8478:STX5
uniprot id: A0A8C3IK63
names: Similarity
messages: Belongs to the syntaxin family.

8478:ZNF711
gene id: 8478:ZNF711
uniprot id: A0A8C3HLC9
uniprot id: A0A8C3HLF8
names: Subcellular Location Annotation
messages: Nucleus

8478:USP2
gene id: 8478:USP2
uniprot id: A0A8C3FK91
names: Similarity
messages: Belongs to the peptidase C19 family.

8478:ERC1
gene id: 8478:ERC1
uniprot id: A0A8C3IVN1
uniprot id: A0A8C3IY58
uniprot id: A0A8C3IYB0
names: Subcellular Location Annotation
messages: Cytoplasm

8478:ZFP36L1
gene id: 8478:ZFP36L1
uniprot id: A0A8C3IAD0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8478:EVA1B
gene id: 8478:EVA1B
uniprot id: A0A8C3I2B7
names: Similarity
messages: Belongs to the EVA1 family.

8478:GHSR
gene id: 8478:GHSR
uniprot id: A0A8C3HRT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:POLA2
gene id: 8478:POLA2
uniprot id: A0A8C3IHR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

8478:UXS1
gene id: 8478:UXS1
uniprot id: A0A8C3FHR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

8478:SCRN1
gene id: 8478:SCRN1
uniprot id: A0A8C3PCB2
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

8478:DHRS7B
gene id: 8478:DHRS7B
uniprot id: A0A8C3I7N5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8478:HTR1F
gene id: 8478:HTR1F
uniprot id: A0A8C3FIJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

8478:LANCL2
gene id: 8478:LANCL2
uniprot id: A0A8C3IL63
uniprot id: A0A8C3ILC4
names: Similarity
messages: Belongs to the LanC-like protein family.

8478:BORCS5
gene id: 8478:BORCS5
uniprot id: A0A8C3F3J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

8478:FAM131C
gene id: 8478:FAM131C
uniprot id: A0A8C3FYG4
names: Similarity
messages: Belongs to the FAM131 family.

8478:MAPK8IP1
gene id: 8478:MAPK8IP1
uniprot id: A0A8C3HF30
uniprot id: A0A8C3HFB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

8478:MVD
gene id: 8478:MVD
uniprot id: A0A8C3IH71
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

8478:RBKS
gene id: 8478:RBKS
uniprot id: A0A8C3IQU8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

8478:A4GNT
gene id: 8478:A4GNT
uniprot id: A0A8C3EYX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

8478:RCAN2
gene id: 8478:RCAN2
uniprot id: A0A8C3IDF4
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

8478:LOC101938583
gene id: 8478:LOC101938583
uniprot id: A0A8C3FTP2
uniprot id: A0A8C3HAV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

8478:OLFML2A
gene id: 8478:OLFML2A
uniprot id: A0A8C3IZ83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:MNX1
gene id: 8478:MNX1
uniprot id: A0A8C3I190
names: Subcellular Location Annotation
messages: Nucleus

8478:SHH
gene id: 8478:SHH
uniprot id: A0A8C3HZ65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8478:CHM
gene id: 8478:CHM
uniprot id: A0A8C3HLW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

8478:DARS2
gene id: 8478:DARS2
uniprot id: A0A8C3HMA2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

8478:SNX30
gene id: 8478:SNX30
uniprot id: A0A8C3FQS8
uniprot id: A0A8C3FRM4
names: Similarity
messages: Belongs to the sorting nexin family.

8478:SLC35D1
gene id: 8478:SLC35D1
uniprot id: A0A8C3F1T6
names: Subcellular Location Annotation
messages: Membrane

8478:INPP5D
gene id: 8478:INPP5D
uniprot id: A0A8C3IIG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

8478:LOC101946315
gene id: 8478:LOC101946315
uniprot id: A0A8C3FKZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

8478:AIMP2
gene id: 8478:AIMP2
uniprot id: A0A8C3I4E4
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

8478:HYAL4
gene id: 8478:HYAL4
uniprot id: A0A8C3PB48
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8478:AGAP2
gene id: 8478:AGAP2
uniprot id: A0A8C3HXX6
names: Similarity
messages: Belongs to the centaurin gamma-like family.

8478:LOC101938637
gene id: 8478:LOC101938637
uniprot id: A0A8C3IJ08
uniprot id: A0A8C3PD06
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

8478:LOC101934897
gene id: 8478:LOC101934897
uniprot id: A0A8C3PBQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8478:FABP7
gene id: 8478:FABP7
uniprot id: A0A8C3HZX6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8478:GTPBP10
gene id: 8478:GTPBP10
uniprot id: A0A8C3I9Q6
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

8478:PTHLH
gene id: 8478:PTHLH
uniprot id: A0A8C3F0T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8478:SAMM50
gene id: 8478:SAMM50
uniprot id: A0A8C3IQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

8478:LOC101931195
gene id: 8478:LOC101931195
uniprot id: A0A8C3F0K5
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

8478:NAA30
gene id: 8478:NAA30
uniprot id: A0A8C3IPP2
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

8478:NUBP2
gene id: 8478:NUBP2
uniprot id: A0A8C3PCU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

8478:IPO8
gene id: 8478:IPO8
uniprot id: A0A8C3PFN7
names: Subcellular Location Annotation
messages: Cytoplasm

8478:SH3RF2
gene id: 8478:SH3RF2
uniprot id: A0A8C3FLX7
names: Similarity
messages: Belongs to the SH3RF family.

8478:TMEM63A
gene id: 8478:TMEM63A
uniprot id: A0A8C3HD74
uniprot id: A0A8C3P2X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

8478:RPS3A
gene id: 8478:RPS3A
uniprot id: A0A8C3IQQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Cytoplasm
messages: nucleolus

8478:SLC14A2
gene id: 8478:SLC14A2
uniprot id: A0A8C3IPF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

8478:MAP4K2
gene id: 8478:MAP4K2
uniprot id: A0A8C3IHF8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

8478:PIGH
gene id: 8478:PIGH
uniprot id: A0A8C3PBH1
names: Similarity
messages: Belongs to the PIGH family.

8478:GNPTAB
gene id: 8478:GNPTAB
uniprot id: A0A8C3H5B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

8478:LOC101940259
gene id: 8478:LOC101940259
uniprot id: A0A8C3F9C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8478:CHST1
gene id: 8478:CHST1
uniprot id: A0A8C3HFA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8478:SMARCA2
gene id: 8478:SMARCA2
uniprot id: A0A8C3INN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8478:EIF2S1
gene id: 8478:EIF2S1
uniprot id: A0A8C3FGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

8478:MGRN1
gene id: 8478:MGRN1
uniprot id: A0A8C3P2B2
uniprot id: A0A8C3P2C5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

8478:STIP1
gene id: 8478:STIP1
uniprot id: A0A8C3IGK3
names: Subcellular Location Annotation
messages: Cytoplasm

8478:CHST12
gene id: 8478:CHST12
uniprot id: A0A8C3I6Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:MAL
gene id: 8478:MAL
uniprot id: A0A8C3HYP5
names: Subcellular Location Annotation
messages: Membrane

8478:MCM8
gene id: 8478:MCM8
uniprot id: A0A8C3IGB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8478:GINS1
gene id: 8478:GINS1
uniprot id: A0A8C3HWW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

8478:OXSR1
gene id: 8478:OXSR1
uniprot id: A0A8C3HZF2
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8478:LOC101937751
gene id: 8478:LOC101937751
uniprot id: A0A8C3IK17
names: Similarity
messages: Belongs to the ARTD/PARP family.

8478:TIMM9
gene id: 8478:TIMM9
uniprot id: A0A8C3INZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8478:ORAI1
gene id: 8478:ORAI1
uniprot id: A0A8C3IQQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8478:SLC25A26
gene id: 8478:SLC25A26
uniprot id: A0A8C3IUD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8478:INTS9
gene id: 8478:INTS9
uniprot id: A0A8C3I4X4
uniprot id: A0A8C3I759
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

8478:GRPEL2
gene id: 8478:GRPEL2
uniprot id: A0A8C3FJV4
names: Similarity
messages: Belongs to the GrpE family.

8478:ADRB2
gene id: 8478:ADRB2
uniprot id: A0A8C3FJI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane

8478:LOC101942324
gene id: 8478:LOC101942324
uniprot id: A0A8C3IH08
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8478:AQP11
gene id: 8478:AQP11
uniprot id: A0A8C3IXQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

8478:SOX3
gene id: 8478:SOX3
uniprot id: A0A8C3HUH8
names: Subcellular Location Annotation
messages: Nucleus

8478:STT3A
gene id: 8478:STT3A
uniprot id: A0A8C3FYQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

8478:PPIB
gene id: 8478:PPIB
uniprot id: A0A8C3FEQ2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8478:ASRGL1
gene id: 8478:ASRGL1
uniprot id: A0A8C3HYA9
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8478:CD109
gene id: 8478:CD109
uniprot id: A0A8C3IHC7
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

8478:ALG12
gene id: 8478:ALG12
uniprot id: A0A8C3I931
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:RPE65
gene id: 8478:RPE65
uniprot id: A0A8C3F3Z4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8478:TMEM41A
gene id: 8478:TMEM41A
uniprot id: A0A8C3FNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

8478:TRMT1L
gene id: 8478:TRMT1L
uniprot id: A0A8C3HQD9
uniprot id: A0A8C3P7P3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

8478:BLVRA
gene id: 8478:BLVRA
uniprot id: A0A8C3INV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.
messages: Monomer.
messages: Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
messages: cytosol

8478:ASPHD2
gene id: 8478:ASPHD2
uniprot id: A0A8C3IAP7
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

8478:AHR
gene id: 8478:AHR
uniprot id: A0A8C3IAV8
names: Subcellular Location Annotation
messages: Cytoplasm

8478:MYSM1
gene id: 8478:MYSM1
uniprot id: A0A8C3HKR5
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

8478:DYNC1I1
gene id: 8478:DYNC1I1
uniprot id: A0A8C3IN49
uniprot id: A0A8C3PDL2
names: Similarity
messages: Belongs to the dynein intermediate chain family.

8478:PHKB
gene id: 8478:PHKB
uniprot id: A0A8C3HRM7
uniprot id: A0A8C3HRQ8
uniprot id: A0A8C3HSC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

8478:PSMA3
gene id: 8478:PSMA3
uniprot id: A0A8C3INU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8478:LOC101946340
gene id: 8478:LOC101946340
uniprot id: A0A8C3FJ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

8478:KCND3
gene id: 8478:KCND3
uniprot id: A0A8C3I8U4
uniprot id: A0A8C3IB13
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8478:UBA3
gene id: 8478:UBA3
uniprot id: A0A8C3EY20
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

8478:HOOK1
gene id: 8478:HOOK1
uniprot id: A0A8C3HLB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

8478:GALNT1
gene id: 8478:GALNT1
uniprot id: A0A8C3FDP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8478:PER2
gene id: 8478:PER2
uniprot id: A0A8C3I248
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8478:CASQ2
gene id: 8478:CASQ2
uniprot id: A0A8C3F9T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8478:C7H18orf32
gene id: 8478:C7H18orf32
uniprot id: A0A8C3PEH0
names: Similarity
messages: Belongs to the UPF0729 family.

8478:ESRRA
gene id: 8478:ESRRA
uniprot id: A0A8C3IJT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8478:KCNH8
gene id: 8478:KCNH8
uniprot id: A0A8C3IFQ7
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8478:MND1
gene id: 8478:MND1
uniprot id: A0A8C3INI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

8478:LOC101941138
gene id: 8478:LOC101941138
uniprot id: A0A8C3I718
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8478:LOC101950370
gene id: 8478:LOC101950370
uniprot id: A0A8C3IBH1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

8478:LOC101941762
gene id: 8478:LOC101941762
uniprot id: A0A8C3IG46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

8478:EGFL7
gene id: 8478:EGFL7
uniprot id: A0A8C3HDW8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:LOC101953721
gene id: 8478:LOC101953721
uniprot id: A0A8C3HAD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Secreted

8478:NME5
gene id: 8478:NME5
uniprot id: A0A8C3FVG4
names: Similarity
messages: Belongs to the NDK family.

8478:MAP3K9
gene id: 8478:MAP3K9
uniprot id: A0A8C3PC19
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

8478:NMNAT1
gene id: 8478:NMNAT1
uniprot id: A0A8C3ICE4
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

8478:AP3B2
gene id: 8478:AP3B2
uniprot id: A0A8C3FEU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

8478:PITPNM2
gene id: 8478:PITPNM2
uniprot id: A0A8C3IP78
uniprot id: A0A8C3IQ94
uniprot id: A0A8C3IQA3
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

8478:IRX2
gene id: 8478:IRX2
uniprot id: A0A8C3IZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8478:MMP15
gene id: 8478:MMP15
uniprot id: A0A8C3IWL6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8478:LOC101945045
gene id: 8478:LOC101945045
uniprot id: A0A8C3FPJ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

8478:SEPTIN8
gene id: 8478:SEPTIN8
uniprot id: A0A8C3HU31
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8478:PIK3CB
gene id: 8478:PIK3CB
uniprot id: A0A8C3I1V2
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8478:EIF1B
gene id: 8478:EIF1B
uniprot id: A0A8C3F082
names: Similarity
messages: Belongs to the SUI1 family.

8478:HOXA7
gene id: 8478:HOXA7
uniprot id: A0A8C3PCA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

8478:RPA3
gene id: 8478:RPA3
uniprot id: A0A8C3IKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

8478:JAK2
gene id: 8478:JAK2
uniprot id: A0A8C3IMG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

8478:GARS1
gene id: 8478:GARS1
uniprot id: A0A8C3I324
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

8478:ALKAL2
gene id: 8478:ALKAL2
uniprot id: A0A8C3IAJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

8478:CPNE3
gene id: 8478:CPNE3
uniprot id: A0A8C3FRG8
names: Similarity
messages: Belongs to the copine family.

8478:SRPRA
gene id: 8478:SRPRA
uniprot id: A0A8C3FWX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:B4GALT2
gene id: 8478:B4GALT2
uniprot id: A0A8C3F758
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8478:ITGB8
gene id: 8478:ITGB8
uniprot id: A0A8C3EZ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

8478:STC2
gene id: 8478:STC2
uniprot id: A0A8C3FKJ4
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

8478:LOC103305696
gene id: 8478:LOC103305696
uniprot id: A0A8C3IEB1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8478:SPSB4
gene id: 8478:SPSB4
uniprot id: A0A8C3I297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

8478:SPICE1
gene id: 8478:SPICE1
uniprot id: A0A8C3F237
names: Subcellular Location Annotation
messages: centriole
messages: spindle

8478:SDC1
gene id: 8478:SDC1
uniprot id: A0A8C3PAK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8478:SSBP1
gene id: 8478:SSBP1
uniprot id: A0A8C3FXX8
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8478:TAF1
gene id: 8478:TAF1
uniprot id: A0A8C3HTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

8478:ARHGAP32
gene id: 8478:ARHGAP32
uniprot id: A0A8C3IU19
uniprot id: A0A8C3IUP1
uniprot id: A0A8C3PFF7
uniprot id: A0A8C3PFJ7
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

8478:BRD1
gene id: 8478:BRD1
uniprot id: A0A8C3PBI4
names: Subcellular Location Annotation
messages: Nucleus

8478:DLX6
gene id: 8478:DLX6
uniprot id: A0A8C3IJN9
names: Subcellular Location Annotation
messages: Nucleus

8478:RFTN2
gene id: 8478:RFTN2
uniprot id: A0A8C3IB05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

8478:STK17A
gene id: 8478:STK17A
uniprot id: A0A8C3IK99
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:PLA2G4A
gene id: 8478:PLA2G4A
uniprot id: A0A8C3HMG8
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

8478:IP6K2
gene id: 8478:IP6K2
uniprot id: A0A8C3HLC8
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8478:SUCLG2
gene id: 8478:SUCLG2
uniprot id: A0A8C3IUG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

8478:B3GAT3
gene id: 8478:B3GAT3
uniprot id: A0A8C3I054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:RIBC2
gene id: 8478:RIBC2
uniprot id: A0A8C3IMT8
uniprot id: A0A8C3PDJ0
names: Similarity
messages: Belongs to the RIB43A family.

8478:NKX2-5
gene id: 8478:NKX2-5
uniprot id: A0A8C3FJ45
names: Subcellular Location Annotation
messages: Nucleus

8478:FGF1
gene id: 8478:FGF1
uniprot id: A0A8C3HVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

8478:LOC101953726
gene id: 8478:LOC101953726
uniprot id: A0A8C3HRP5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:USP1
gene id: 8478:USP1
uniprot id: A0A8C3HJR0
names: Similarity
messages: Belongs to the peptidase C19 family.

8478:USP20
gene id: 8478:USP20
uniprot id: A0A8C3PCF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

8478:ERMP1
gene id: 8478:ERMP1
uniprot id: A0A8C3IMI0
names: Subcellular Location Annotation
messages: Membrane

8478:FAM20B
gene id: 8478:FAM20B
uniprot id: A0A8C3HM50
names: Similarity
messages: Belongs to the FAM20 family.

8478:MED7
gene id: 8478:MED7
uniprot id: A0A8C3F3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

8478:ADCY7
gene id: 8478:ADCY7
uniprot id: A0A8C3HRD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8478:TMEM123
gene id: 8478:TMEM123
uniprot id: A0A8C3IWF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

8478:RPS6KA6
gene id: 8478:RPS6KA6
uniprot id: A0A8C3HLH3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8478:GALNT14
gene id: 8478:GALNT14
uniprot id: A0A8C3HCP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8478:ZDHHC21
gene id: 8478:ZDHHC21
uniprot id: A0A8C3PED3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:TBCCD1
gene id: 8478:TBCCD1
uniprot id: A0A8C3H4Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

8478:ITM2C
gene id: 8478:ITM2C
uniprot id: A0A8C3PA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8478:PPARGC1B
gene id: 8478:PPARGC1B
uniprot id: A0A8C3FK12
uniprot id: A0A8C3FNL4
names: Subcellular Location Annotation
messages: Nucleus

8478:SAR1B
gene id: 8478:SAR1B
uniprot id: A0A8C3FLT6
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

8478:BZW1
gene id: 8478:BZW1
uniprot id: A0A8C3HCF7
names: Similarity
messages: Belongs to the BZW family.

8478:AADAC
gene id: 8478:AADAC
uniprot id: A0A8C3I0G9
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8478:THNSL1
gene id: 8478:THNSL1
uniprot id: A0A8C3HQ41
names: Similarity
messages: Belongs to the threonine synthase family.

8478:SPTB
gene id: 8478:SPTB
uniprot id: A0A8C3HUF8
names: Similarity
messages: Belongs to the spectrin family.

8478:DACT2
gene id: 8478:DACT2
uniprot id: A0A8C3HEQ5
names: Similarity
messages: Belongs to the dapper family.

8478:CAPRIN1
gene id: 8478:CAPRIN1
uniprot id: A0A8C3HEW8
names: Similarity
messages: Belongs to the caprin family.

8478:LOC101934214
gene id: 8478:LOC101934214
uniprot id: A0A8C3HDF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8478:MAPK9
gene id: 8478:MAPK9
uniprot id: A0A8C3FP52
uniprot id: A0A8C3FVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8478:LOC101937115
gene id: 8478:LOC101937115
uniprot id: A0A8C3IG51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:ATP2A2
gene id: 8478:ATP2A2
uniprot id: A0A8C3PER6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8478:UCK1
gene id: 8478:UCK1
uniprot id: A0A8C3I9J6
names: Similarity
messages: Belongs to the uridine kinase family.

8478:MERTK
gene id: 8478:MERTK
uniprot id: A0A8C3FDH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

8478:TNFRSF1B
gene id: 8478:TNFRSF1B
uniprot id: A0A8C3IC16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:ELF2
gene id: 8478:ELF2
uniprot id: A0A8C3IV59
uniprot id: A0A8C3PFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8478:TAGLN3
gene id: 8478:TAGLN3
uniprot id: A0A8C3FDU2
names: Similarity
messages: Belongs to the calponin family.

8478:SLC12A4
gene id: 8478:SLC12A4
uniprot id: A0A8C3HDH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8478:GRHPR
gene id: 8478:GRHPR
uniprot id: A0A8C3FII6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8478:UGCG
gene id: 8478:UGCG
uniprot id: A0A8C3FN51
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

8478:DOCK8
gene id: 8478:DOCK8
uniprot id: A0A8C3PEB7
names: Similarity
messages: Belongs to the DOCK family.

8478:LOC101931921
gene id: 8478:LOC101931921
uniprot id: A0A8C3FND1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

8478:PPP2R5D
gene id: 8478:PPP2R5D
uniprot id: A0A8C3FF16
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8478:ATP1B1
gene id: 8478:ATP1B1
uniprot id: A0A8C3F8J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8478:FERMT1
gene id: 8478:FERMT1
uniprot id: A0A8C3IGX7
names: Similarity
messages: Belongs to the kindlin family.

8478:PIH1D2
gene id: 8478:PIH1D2
uniprot id: A0A8C3FPG3
names: Similarity
messages: Belongs to the PIH1 family.

8478:DPF2
gene id: 8478:DPF2
uniprot id: A0A8C3IKE3
names: Similarity
messages: Belongs to the requiem/DPF family.

8478:ABL1
gene id: 8478:ABL1
uniprot id: A0A8C3IDJ4
uniprot id: A0A8C3PCD8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8478:TSPAN13
gene id: 8478:TSPAN13
uniprot id: A0A8C3IB00
names: Subcellular Location Annotation
messages: Membrane

8478:HSPA5
gene id: 8478:HSPA5
uniprot id: A0A8C3J173
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

8478:ACO1
gene id: 8478:ACO1
uniprot id: A0A8C3FKM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

8478:CASKIN1
gene id: 8478:CASKIN1
uniprot id: A0A8C3F120
names: Subcellular Location Annotation
messages: Cytoplasm

8478:MRPS9
gene id: 8478:MRPS9
uniprot id: A0A8C3FLL0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8478:IAH1
gene id: 8478:IAH1
uniprot id: A0A8C3HKJ3
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

8478:GNL2
gene id: 8478:GNL2
uniprot id: A0A8C3I256
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

8478:C9H3orf70
gene id: 8478:C9H3orf70
uniprot id: A0A8C3FJ86
names: Similarity
messages: Belongs to the UPF0524 family.

8478:CBFB
gene id: 8478:CBFB
uniprot id: A0A8C3HD30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

8478:NATD1
gene id: 8478:NATD1
uniprot id: A0A8C3I7G0
names: Similarity
messages: Belongs to the NATD1 family.

8478:BRAF
gene id: 8478:BRAF
uniprot id: A0A8C3P2F7
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

8478:EIF3B
gene id: 8478:EIF3B
uniprot id: A0A8C3PB23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

8478:EIF2B1
gene id: 8478:EIF2B1
uniprot id: A0A8C3IQ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

8478:CHCHD4
gene id: 8478:CHCHD4
uniprot id: A0A8C3HMR5
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

8478:ACTR3
gene id: 8478:ACTR3
uniprot id: A0A8C3FUG7
names: Similarity
messages: Belongs to the actin family.

8478:LIPH
gene id: 8478:LIPH
uniprot id: A0A8C3FQZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

8478:CRYAB
gene id: 8478:CRYAB
uniprot id: A0A8C3FQJ7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8478:ZDHHC12
gene id: 8478:ZDHHC12
uniprot id: A0A8C3IGD4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8478:FERMT3
gene id: 8478:FERMT3
uniprot id: A0A8C3IGK0
names: Similarity
messages: Belongs to the kindlin family.

8478:NR2E3
gene id: 8478:NR2E3
uniprot id: A0A8C3FMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

8478:PIN4
gene id: 8478:PIN4
uniprot id: A0A8C3HD29
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

8478:TMC5
gene id: 8478:TMC5
uniprot id: A0A8C3FVS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8478:ELK4
gene id: 8478:ELK4
uniprot id: A0A8C3F2K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8478:VPS8
gene id: 8478:VPS8
uniprot id: A0A8C3FNZ1
names: Similarity
messages: Belongs to the VPS8 family.

8478:MMP7
gene id: 8478:MMP7
uniprot id: A0A8C3IWK3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8478:MTHFD1L
gene id: 8478:MTHFD1L
uniprot id: A0A8C3HVC2
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

8478:GLO1
gene id: 8478:GLO1
uniprot id: A0A8C3IM23
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

8478:CAPZA2
gene id: 8478:CAPZA2
uniprot id: A0A8C3H955
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8478:NDUFS3
gene id: 8478:NDUFS3
uniprot id: A0A8C3HUF2
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

8478:PARL
gene id: 8478:PARL
uniprot id: A0A8C3I213
names: Subcellular Location Annotation
messages: Membrane

8478:AMZ1
gene id: 8478:AMZ1
uniprot id: A0A8C3I976
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

8478:RHPN2
gene id: 8478:RHPN2
uniprot id: A0A8C3EZ82
names: Similarity
messages: Belongs to the RHPN family.

8478:LOXL1
gene id: 8478:LOXL1
uniprot id: A0A8C3FNP9
uniprot id: A0A8C3FR35
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8478:GRIA1
gene id: 8478:GRIA1
uniprot id: A0A8C3F635
uniprot id: A0A8C3H5Y5
uniprot id: A0A8C3H6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8478:OCRL
gene id: 8478:OCRL
uniprot id: A0A8C3HD24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

8478:TOMM5
gene id: 8478:TOMM5
uniprot id: A0A8C3FIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

8478:SF3B6
gene id: 8478:SF3B6
uniprot id: A0A8C3I5H2
names: Subcellular Location Annotation
messages: Nucleus

8478:GORASP1
gene id: 8478:GORASP1
uniprot id: A0A8C3HZE1
names: Similarity
messages: Belongs to the GORASP family.

8478:C1H2orf49
gene id: 8478:C1H2orf49
uniprot id: A0A8C3FN84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

8478:LOC101951429
gene id: 8478:LOC101951429
uniprot id: A0A8C3HQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

8478:SYNJ2
gene id: 8478:SYNJ2
uniprot id: A0A8C3HSD2
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

8478:CHFR
gene id: 8478:CHFR
uniprot id: A0A8C3IY01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

8478:PSMB2
gene id: 8478:PSMB2
uniprot id: A0A8C3I0I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8478:B4GALT4
gene id: 8478:B4GALT4
uniprot id: A0A8C3FA96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8478:ADAMTS15
gene id: 8478:ADAMTS15
uniprot id: A0A8C3IXJ8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8478:PLOD1
gene id: 8478:PLOD1
uniprot id: A0A8C3PBY7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8478:SLC25A13
gene id: 8478:SLC25A13
uniprot id: A0A8C3IJV7
uniprot id: A0A8C3IM60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8478:LOC101939533
gene id: 8478:LOC101939533
uniprot id: A0A8C3J171
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

8478:LOC101950687
gene id: 8478:LOC101950687
uniprot id: A0A8C3IAP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

8478:TRAF6
gene id: 8478:TRAF6
uniprot id: A0A8C3HEV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

8478:SATB1
gene id: 8478:SATB1
uniprot id: A0A8C3ID43
uniprot id: A0A8C3ID74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8478:PFKL
gene id: 8478:PFKL
uniprot id: A0A8C3H5G4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:MMAA
gene id: 8478:MMAA
uniprot id: A0A8C3IWR4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

8478:CRPPA
gene id: 8478:CRPPA
uniprot id: A0A8C3IE46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

8478:HEATR5B
gene id: 8478:HEATR5B
uniprot id: A0A8C3IK07
names: Similarity
messages: Belongs to the HEATR5 family.

8478:LOC101946790
gene id: 8478:LOC101946790
uniprot id: A0A8C3PBI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

8478:FAM98A
gene id: 8478:FAM98A
uniprot id: A0A8C3IQ07
names: Similarity
messages: Belongs to the FAM98 family.

8478:EIF1AD
gene id: 8478:EIF1AD
uniprot id: A0A8C3IIR1
names: Similarity
messages: Belongs to the EIF1AD family.

8478:CD247
gene id: 8478:CD247
uniprot id: A0A8C3H8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

8478:CHEK1
gene id: 8478:CHEK1
uniprot id: A0A8C3FWK0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

8478:PRPF38A
gene id: 8478:PRPF38A
uniprot id: A0A8C3HMZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

8478:UBE2I
gene id: 8478:UBE2I
uniprot id: A0A8C3F4X6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8478:MSN
gene id: 8478:MSN
uniprot id: A0A8C3H924
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8478:C4H11orf49
gene id: 8478:C4H11orf49
uniprot id: A0A8C3HPN7
uniprot id: A0A8C3P7J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: cytoskeleton

8478:SLC25A43
gene id: 8478:SLC25A43
uniprot id: A0A8C3I7P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8478:NDUFB8
gene id: 8478:NDUFB8
uniprot id: A0A8C3PAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8478:PCSK5
gene id: 8478:PCSK5
uniprot id: A0A8C3I3U0
names: Similarity
messages: Belongs to the peptidase S8 family.

8478:FGF13
gene id: 8478:FGF13
uniprot id: A0A8C3IRL6
uniprot id: A0A8C3IUJ5
uniprot id: A0A8C3PEX7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8478:FOXI1
gene id: 8478:FOXI1
uniprot id: A0A8C3ILK3
names: Subcellular Location Annotation
messages: Nucleus

8478:HMMR
gene id: 8478:HMMR
uniprot id: A0A8C3FKZ4
uniprot id: A0A8C3FLN1
names: Subcellular Location Annotation
messages: spindle

8478:AGRN
gene id: 8478:AGRN
uniprot id: A0A8C3IEC6
uniprot id: A0A8C3IF58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:MARK1
gene id: 8478:MARK1
uniprot id: A0A8C3F3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8478:EFEMP2
gene id: 8478:EFEMP2
uniprot id: A0A8C3IIJ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:UBE2E1
gene id: 8478:UBE2E1
uniprot id: A0A8C3ICM8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8478:SMAD1
gene id: 8478:SMAD1
uniprot id: A0A8C3PFY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8478:PRDX5
gene id: 8478:PRDX5
uniprot id: A0A8C3IIT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

8478:LYRM1
gene id: 8478:LYRM1
uniprot id: A0A8C3I151
names: Similarity
messages: Belongs to the complex I LYR family.

8478:MLF1
gene id: 8478:MLF1
uniprot id: A0A8C3HZ27
uniprot id: A0A8C3HZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

8478:ABCG4
gene id: 8478:ABCG4
uniprot id: A0A8C3FJW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8478:LOC101936633
gene id: 8478:LOC101936633
uniprot id: A0A8C3HB41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8478:LOC101947030
gene id: 8478:LOC101947030
uniprot id: A0A8C3I0F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

8478:LOC101950620
gene id: 8478:LOC101950620
uniprot id: A0A8C3P4A2
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:BARHL1
gene id: 8478:BARHL1
uniprot id: A0A8C3IAX8
names: Subcellular Location Annotation
messages: Nucleus

8478:PRICKLE2
gene id: 8478:PRICKLE2
uniprot id: A0A8C3ISA2
uniprot id: A0A8C3IUC2
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8478:TFDP2
gene id: 8478:TFDP2
uniprot id: A0A8C3H5X1
uniprot id: A0A8C3H6B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8478:POLR3F
gene id: 8478:POLR3F
uniprot id: A0A8C3PD01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

8478:DPAGT1
gene id: 8478:DPAGT1
uniprot id: A0A8C3FEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:ARG2
gene id: 8478:ARG2
uniprot id: A0A8C3FFW9
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

8478:BMP2
gene id: 8478:BMP2
uniprot id: A0A8C3IG15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8478:WNT7A
gene id: 8478:WNT7A
uniprot id: A0A8C3PAE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8478:SSTR5
gene id: 8478:SSTR5
uniprot id: A0A8C3I893
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8478:RFX3
gene id: 8478:RFX3
uniprot id: A0A8C3INQ0
names: Subcellular Location Annotation
messages: Nucleus

8478:LOC101948210
gene id: 8478:LOC101948210
uniprot id: A0A8C3HPW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SCAP family.
messages: COPII-coated vesicle membrane
messages: Golgi apparatus membrane

8478:LLPH
gene id: 8478:LLPH
uniprot id: A0A8C3INR8
names: Similarity
messages: Belongs to the learning-associated protein family.

8478:LOC101952560
gene id: 8478:LOC101952560
uniprot id: A0A8C3HCD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FOXJ1 family.
messages: Nucleus

8478:ATP10D
gene id: 8478:ATP10D
uniprot id: A0A8C3IX77
uniprot id: A0A8C3IXC2
uniprot id: A0A8C3J043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8478:LOC101950036
gene id: 8478:LOC101950036
uniprot id: A0A8C3HUL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle
messages: nucleoplasm

8478:UBE2G2
gene id: 8478:UBE2G2
uniprot id: A0A8C3F149
uniprot id: A0A8C3F2I9
uniprot id: A0A8C3F7P2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8478:BANF1
gene id: 8478:BANF1
uniprot id: A0A8C3IGD8
names: Subcellular Location Annotation
messages: Nucleus

8478:GSK3B
gene id: 8478:GSK3B
uniprot id: A0A8C3F8T8
uniprot id: A0A8C3FAY9
uniprot id: A0A8C3H6A4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

8478:C3H6orf58
gene id: 8478:C3H6orf58
uniprot id: A0A8C3I150
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

8478:CA5A
gene id: 8478:CA5A
uniprot id: A0A8C3IIX1
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8478:GPT2
gene id: 8478:GPT2
uniprot id: A0A8C3HSR2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8478:SNX5
gene id: 8478:SNX5
uniprot id: A0A8C3IJS8
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

8478:SLC35B2
gene id: 8478:SLC35B2
uniprot id: A0A8C3IRK9
uniprot id: A0A8C3PEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8478:PIK3CD
gene id: 8478:PIK3CD
uniprot id: A0A8C3IDW9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8478:RANBP17
gene id: 8478:RANBP17
uniprot id: A0A8C3I9G2
uniprot id: A0A8C3PBE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

8478:MCRIP2
gene id: 8478:MCRIP2
uniprot id: A0A8C3EZ71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

8478:B4GAT1
gene id: 8478:B4GAT1
uniprot id: A0A8C3IE36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:PALM2AKAP2
gene id: 8478:PALM2AKAP2
uniprot id: A0A8C3FQQ0
uniprot id: A0A8C3FVH7
names: Similarity
messages: Belongs to the paralemmin family.

8478:CELSR3
gene id: 8478:CELSR3
uniprot id: A0A8C3P6R2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

8478:CCDC39
gene id: 8478:CCDC39
uniprot id: A0A8C3F0C7
names: Similarity
messages: Belongs to the CCDC39 family.

8478:PODXL2
gene id: 8478:PODXL2
uniprot id: A0A8C3HLT4
names: Subcellular Location Annotation
messages: Membrane

8478:GALNT16
gene id: 8478:GALNT16
uniprot id: A0A8C3I9Z6
uniprot id: A0A8C3PBN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8478:ATP6V0E1
gene id: 8478:ATP6V0E1
uniprot id: A0A8C3FRK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8478:RAB27A
gene id: 8478:RAB27A
uniprot id: A0A8C3H7C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8478:ATP7A
gene id: 8478:ATP7A
uniprot id: A0A8C3HW06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

8478:PTGR2
gene id: 8478:PTGR2
uniprot id: A0A8C3HI52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

8478:MYOZ3
gene id: 8478:MYOZ3
uniprot id: A0A8C3FTE7
names: Similarity
messages: Belongs to the myozenin family.

8478:CCK
gene id: 8478:CCK
uniprot id: A0A8C3IGM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

8478:EHF
gene id: 8478:EHF
uniprot id: A0A8C3HET2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8478:CUL5
gene id: 8478:CUL5
uniprot id: A0A8C3HZT5
names: Similarity
messages: Belongs to the cullin family.

8478:ME2
gene id: 8478:ME2
uniprot id: A0A8C3PEK0
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

8478:APOOL
gene id: 8478:APOOL
uniprot id: A0A8C3HLF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

8478:FASLG
gene id: 8478:FASLG
uniprot id: A0A8C3FH93
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8478:ST8SIA5
gene id: 8478:ST8SIA5
uniprot id: A0A8C3IQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8478:YME1L1
gene id: 8478:YME1L1
uniprot id: A0A8C3P7T0
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8478:VBP1
gene id: 8478:VBP1
uniprot id: A0A8C3F1R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

8478:TIMM8B
gene id: 8478:TIMM8B
uniprot id: A0A8C3FPF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8478:SRP9
gene id: 8478:SRP9
uniprot id: A0A8C3HD46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

8478:OTUB1
gene id: 8478:OTUB1
uniprot id: A0A8C3IFQ2
names: Similarity
messages: Belongs to the peptidase C65 family.

8478:SYT17
gene id: 8478:SYT17
uniprot id: A0A8C3FUQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Membrane

8478:PLEKHA8
gene id: 8478:PLEKHA8
uniprot id: A0A8C3IFF4
names: Subcellular Location Annotation
messages: trans-Golgi network membrane

8478:MITF
gene id: 8478:MITF
uniprot id: A0A8C3EYX5
uniprot id: A0A8C3EZS6
uniprot id: A0A8C3F405
uniprot id: A0A8C3H4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8478:ENPP1
gene id: 8478:ENPP1
uniprot id: A0A8C3P927
names: Subcellular Location Annotation
messages: Secreted

8478:BPGM
gene id: 8478:BPGM
uniprot id: A0A8C3IYM3
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8478:ATP10B
gene id: 8478:ATP10B
uniprot id: A0A8C3FKL5
uniprot id: A0A8C3FLR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8478:ADAMTS8
gene id: 8478:ADAMTS8
uniprot id: A0A8C3IW30
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8478:COG8
gene id: 8478:COG8
uniprot id: A0A8C3IU88
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG8 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane

8478:LOC101949391
gene id: 8478:LOC101949391
uniprot id: A0A8C3FMG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

8478:LOC101950436
gene id: 8478:LOC101950436
uniprot id: A0A8C3PCX7
names: Similarity
messages: Belongs to the peptidase C1 family.

8478:CAV3
gene id: 8478:CAV3
uniprot id: A0A8C3HN09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8478:KHDRBS2
gene id: 8478:KHDRBS2
uniprot id: A0A8C3PCE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KHDRBS family.
messages: Cytoplasm

8478:PPP6C
gene id: 8478:PPP6C
uniprot id: A0A8C3IYQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8478:MTMR10
gene id: 8478:MTMR10
uniprot id: A0A8C3FV05
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8478:GATB
gene id: 8478:GATB
uniprot id: A0A8C3IQ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8478:LOC101947485
gene id: 8478:LOC101947485
uniprot id: A0A8C3PCA0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8478:BOK
gene id: 8478:BOK
uniprot id: A0A8C3F4C0
names: Similarity
messages: Belongs to the Bcl-2 family.

8478:CCDC126
gene id: 8478:CCDC126
uniprot id: A0A8C3ICS1
names: Subcellular Location Annotation
messages: Secreted

8478:PPP1CB
gene id: 8478:PPP1CB
uniprot id: A0A8C3EXU8
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

8478:LOC101938475
gene id: 8478:LOC101938475
uniprot id: A0A8C3ILZ9
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

8478:LOC101948146
gene id: 8478:LOC101948146
uniprot id: A0A8C3IVL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

8478:RBP7
gene id: 8478:RBP7
uniprot id: A0A8C3IDU2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8478:CD47
gene id: 8478:CD47
uniprot id: A0A8C3FAI5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8478:DUOX2
gene id: 8478:DUOX2
uniprot id: A0A8C3FLP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

8478:CUL3
gene id: 8478:CUL3
uniprot id: A0A8C3I2L4
names: Similarity
messages: Belongs to the cullin family.

8478:ESYT2
gene id: 8478:ESYT2
uniprot id: A0A8C3P8N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8478:ATP11B
gene id: 8478:ATP11B
uniprot id: A0A8C3EYH9
uniprot id: A0A8C3EYK1
uniprot id: A0A8C3F618
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8478:MAFK
gene id: 8478:MAFK
uniprot id: A0A8C3I8S0
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

8478:METTL1
gene id: 8478:METTL1
uniprot id: A0A8C3HYA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

8478:CLGN
gene id: 8478:CLGN
uniprot id: A0A8C3IX11
names: Similarity
messages: Belongs to the calreticulin family.

8478:TMEM59
gene id: 8478:TMEM59
uniprot id: A0A8C3H6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

8478:LOC101933092
gene id: 8478:LOC101933092
uniprot id: A0A8C3FLM9
names: Subcellular Location Annotation
messages: Membrane

8478:NCOA2
gene id: 8478:NCOA2
uniprot id: A0A8C3FI73
uniprot id: A0A8C3FM87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

8478:VMA21
gene id: 8478:VMA21
uniprot id: A0A8C3PB49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

8478:ADCK2
gene id: 8478:ADCK2
uniprot id: A0A8C3HCR1
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8478:AFG3L2
gene id: 8478:AFG3L2
uniprot id: A0A8C3J259
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8478:LOC101938251
gene id: 8478:LOC101938251
uniprot id: A0A8C3J168
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8478:ZEB1
gene id: 8478:ZEB1
uniprot id: A0A8C3HR48
uniprot id: A0A8C3P7U8
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

8478:NOL6
gene id: 8478:NOL6
uniprot id: A0A8C3FF32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
messages: nucleolus

8478:LOC101953642
gene id: 8478:LOC101953642
uniprot id: A0A8C3HEU9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8478:KDM4C
gene id: 8478:KDM4C
uniprot id: A0A8C3IQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

8478:ALDH9A1
gene id: 8478:ALDH9A1
uniprot id: A0A8C3HMF2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8478:SFRP1
gene id: 8478:SFRP1
uniprot id: A0A8C3F8P1
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:PIM3
gene id: 8478:PIM3
uniprot id: A0A8C3PBH5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8478:FGD5
gene id: 8478:FGD5
uniprot id: A0A8C3HMB7
names: Subcellular Location Annotation
messages: cytoskeleton

8478:SENP8
gene id: 8478:SENP8
uniprot id: A0A8C3FFM9
names: Similarity
messages: Belongs to the peptidase C48 family.

8478:GPN3
gene id: 8478:GPN3
uniprot id: A0A8C3IRB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

8478:ABRACL
gene id: 8478:ABRACL
uniprot id: A0A8C3HVV0
names: Similarity
messages: Belongs to the costars family.

8478:SSRP1
gene id: 8478:SSRP1
uniprot id: A0A8C3HU35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

8478:SMAD4
gene id: 8478:SMAD4
uniprot id: A0A8C3INY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8478:VEPH1
gene id: 8478:VEPH1
uniprot id: A0A8C3HZ08
names: Similarity
messages: Belongs to the MELT/VEPH family.

8478:LOC101937633
gene id: 8478:LOC101937633
uniprot id: A0A8C3IJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

8478:CRB2
gene id: 8478:CRB2
uniprot id: A0A8C3FT13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8478:SLC9A6
gene id: 8478:SLC9A6
uniprot id: A0A8C3IQM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

8478:AKT3
gene id: 8478:AKT3
uniprot id: A0A8C3FVM9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8478:ZFHX4
gene id: 8478:ZFHX4
uniprot id: A0A8C3H943
names: Subcellular Location Annotation
messages: Nucleus

8478:TSPAN6
gene id: 8478:TSPAN6
uniprot id: A0A8C3HKY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8478:MAPKAPK2
gene id: 8478:MAPKAPK2
uniprot id: A0A8C3H664
names: Similarity
messages: Belongs to the protein kinase superfamily.

8478:FXR1
gene id: 8478:FXR1
uniprot id: A0A8C3EYF5
uniprot id: A0A8C3EZ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule

8478:CCNB2
gene id: 8478:CCNB2
uniprot id: A0A8C3FYP8
names: Similarity
messages: Belongs to the cyclin family.

8478:DCLK2
gene id: 8478:DCLK2
uniprot id: A0A8C3IU65
uniprot id: A0A8C3IV90
uniprot id: A0A8C3IXX7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8478:ACSL6
gene id: 8478:ACSL6
uniprot id: A0A8C3IN37
uniprot id: A0A8C3IQV4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8478:PUS7
gene id: 8478:PUS7
uniprot id: A0A8C3F241
uniprot id: A0A8C3F4A6
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

8478:SCNN1G
gene id: 8478:SCNN1G
uniprot id: A0A8C3F4P6
names: Subcellular Location Annotation
messages: Membrane

8478:PSENEN
gene id: 8478:PSENEN
uniprot id: A0A8C3F3K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

8478:XYLB
gene id: 8478:XYLB
uniprot id: A0A8C3I0D3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

8478:MAPK4
gene id: 8478:MAPK4
uniprot id: A0A8C3IMZ3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

8478:RHBDD1
gene id: 8478:RHBDD1
uniprot id: A0A8C3I4H3
names: Subcellular Location Annotation
messages: Membrane

8478:STEAP4
gene id: 8478:STEAP4
uniprot id: A0A8C3I8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8478:RPL17
gene id: 8478:RPL17
uniprot id: A0A8C3IPS5
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.