8187:prkab1a
gene id: 8187:prkab1a
uniprot id: A0A4W6C3F5
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

8187:tex261
gene id: 8187:tex261
uniprot id: A0A4W6D861
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

8187:LOC108893209
gene id: 8187:LOC108893209
uniprot id: A0A4W6F0B2
names: Subcellular Location Annotation
messages: Membrane

8187:ints12
gene id: 8187:ints12
uniprot id: A0A4W6CAC1
names: Similarity
messages: Belongs to the Integrator subunit 12 family.

8187:cldn7a
gene id: 8187:cldn7a
uniprot id: A0A4W6DEQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:pym1
gene id: 8187:pym1
uniprot id: A0A4W6EC05
names: Similarity
names: Subunit
messages: Belongs to the pym family.
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

8187:rspo1
gene id: 8187:rspo1
uniprot id: A0A4W6C634
names: Similarity
messages: Belongs to the R-spondin family.

8187:rpl8
gene id: 8187:rpl8
uniprot id: A0A4W6DHQ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

8187:fa2h
gene id: 8187:fa2h
uniprot id: A0A4W6EKN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:tpd52
gene id: 8187:tpd52
uniprot id: A0A4W6DWG3
names: Similarity
messages: Belongs to the TPD52 family.

8187:mast3a
gene id: 8187:mast3a
uniprot id: A0A4W6F579
uniprot id: A0A4W6F7R2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

8187:flt3
gene id: 8187:flt3
uniprot id: A0A4W6DNS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8187:ccr10
gene id: 8187:ccr10
uniprot id: A0A4W6E984
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:npl
gene id: 8187:npl
uniprot id: A0A4W6FSW9
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

8187:thg1l
gene id: 8187:thg1l
uniprot id: A0A4W6CRS7
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

8187:rtn1a
gene id: 8187:rtn1a
uniprot id: A0A4W6FJ04
uniprot id: A0A4W6FKA9
uniprot id: A0A4W6FL27
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108880226
gene id: 8187:LOC108880226
uniprot id: A0A4W6DXS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8187:gal3st2
gene id: 8187:gal3st2
uniprot id: A0A4W6CNX0
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8187:yaf2
gene id: 8187:yaf2
uniprot id: A0A4W6D6Q5
names: Subcellular Location Annotation
messages: Nucleus

8187:apoob
gene id: 8187:apoob
uniprot id: A0A4W6FZT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

8187:mcoln3b
gene id: 8187:mcoln3b
uniprot id: A0A4W6FLQ2
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8187:tbce
gene id: 8187:tbce
uniprot id: A0A4W6DIK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

8187:LOC108889099
gene id: 8187:LOC108889099
uniprot id: A0A4W6BKZ5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8187:rpl31
gene id: 8187:rpl31
uniprot id: A0A4W6G445
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

8187:LOC108891736
gene id: 8187:LOC108891736
uniprot id: A0A4W6C6E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108902485
gene id: 8187:LOC108902485
uniprot id: A0A4W6EYL7
names: Similarity
messages: Belongs to the HARBI1 family.

8187:mtx3
gene id: 8187:mtx3
uniprot id: A0A4W6GAF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

8187:hoxd4a
gene id: 8187:hoxd4a
uniprot id: A0A4W6E7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8187:atf7b
gene id: 8187:atf7b
uniprot id: A0A4W6EE47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

8187:pde6gb
gene id: 8187:pde6gb
uniprot id: A0A4W6FW80
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8187:hs6st1a
gene id: 8187:hs6st1a
uniprot id: A0A4W6E9F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8187:ube2f
gene id: 8187:ube2f
uniprot id: A0A4W6GBR7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:clic3
gene id: 8187:clic3
uniprot id: A0A4W6CDI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

8187:crabp2a
gene id: 8187:crabp2a
uniprot id: A0A4W6FSA6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8187:clic2
gene id: 8187:clic2
uniprot id: A0A4W6FT82
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8187:smg6
gene id: 8187:smg6
uniprot id: A0A4W6FLL6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini.
messages: Plays a role in nonsense-mediated mRNA decay.
messages: The PINc domain confers endonuclease activity and is expected to bind the catalytic metal ion.
messages: cytosol
messages: nucleolus
messages: telomere

8187:rdh5
gene id: 8187:rdh5
uniprot id: A0A4W6E1D3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:efhc2
gene id: 8187:efhc2
uniprot id: A0A4W6EGI3
names: Subcellular Location Annotation
messages: cilium axoneme

8187:LOC108892524
gene id: 8187:LOC108892524
uniprot id: A0A4W6ETW6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8187:ctbs
gene id: 8187:ctbs
uniprot id: A0A4W6E287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Lysosome

8187:nifk
gene id: 8187:nifk
uniprot id: A0A4W6E223
names: Subcellular Location Annotation
messages: nucleolus

8187:LOC108891830
gene id: 8187:LOC108891830
uniprot id: A0A4W6DQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:psmb3
gene id: 8187:psmb3
uniprot id: A0A4W6DAF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8187:LOC108875409
gene id: 8187:LOC108875409
uniprot id: A0A4W6EHK6
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8187:hoxa9b
gene id: 8187:hoxa9b
uniprot id: A0A4W6DK34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8187:LOC108886948
gene id: 8187:LOC108886948
uniprot id: A0A4W6FPM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8187:slc6a11b
gene id: 8187:slc6a11b
uniprot id: A0A4W6EUY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8187:tpk1
gene id: 8187:tpk1
uniprot id: A0A4W6FRF2
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

8187:lypla2
gene id: 8187:lypla2
uniprot id: A0A4W6DPB7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

8187:b3galt1b
gene id: 8187:b3galt1b
uniprot id: A0A4W6FJ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:luc7l
gene id: 8187:luc7l
uniprot id: A0A4W6D8W0
uniprot id: A0A4W6D8W2
names: Similarity
messages: Belongs to the Luc7 family.

8187:tyrp1b
gene id: 8187:tyrp1b
uniprot id: A0A4W6GAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8187:chd1
gene id: 8187:chd1
uniprot id: A0A4W6DPK6
names: Subcellular Location Annotation
messages: Nucleus

8187:sgms1a
gene id: 8187:sgms1a
uniprot id: A0A4W6CPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8187:LOC108893554
gene id: 8187:LOC108893554
uniprot id: A0A4W6E3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:rpl21
gene id: 8187:rpl21
uniprot id: A0A4W6DPT7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

8187:ccr9b
gene id: 8187:ccr9b
uniprot id: A0A4W6E1R9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:LOC108876748
gene id: 8187:LOC108876748
uniprot id: A0A4W6CXI0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
messages: Nucleus
messages: Transcription factor.

8187:haao
gene id: 8187:haao
uniprot id: A0A4W6BM24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

8187:cux2b
gene id: 8187:cux2b
uniprot id: A0A4W6G8Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8187:LOC108883323
gene id: 8187:LOC108883323
uniprot id: A0A4W6BMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8187:LOC108893343
gene id: 8187:LOC108893343
uniprot id: A0A4W6DNR3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

8187:LOC108893869
gene id: 8187:LOC108893869
uniprot id: A0A4W6FIE5
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108887247
gene id: 8187:LOC108887247
uniprot id: A0A4W6FUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

8187:gpr31
gene id: 8187:gpr31
uniprot id: A0A4W6DEG1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:LOC108887886
gene id: 8187:LOC108887886
uniprot id: A0A4W6BME6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108897935
gene id: 8187:LOC108897935
uniprot id: A0A4W6F8N8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8187:mnat1
gene id: 8187:mnat1
uniprot id: A0A4W6FIJ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

8187:paqr4a
gene id: 8187:paqr4a
uniprot id: A0A4W6CCH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8187:pcsk5b
gene id: 8187:pcsk5b
uniprot id: A0A4W6GB65
names: Similarity
messages: Belongs to the peptidase S8 family.

8187:chst1
gene id: 8187:chst1
uniprot id: A0A4W6EJA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8187:vapal
gene id: 8187:vapal
uniprot id: A0A4W6FNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108872971
gene id: 8187:LOC108872971
uniprot id: A0A4W6G2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8187:si:ch211-186j3.6
gene id: 8187:si:ch211-186j3.6
uniprot id: A0A4W6G041
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:olfm2a
gene id: 8187:olfm2a
uniprot id: A0A4W6FWD4
uniprot id: A0A4W6FX48
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8187:gpm6bb
gene id: 8187:gpm6bb
uniprot id: A0A4W6CLI2
uniprot id: A0A4W6CLJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8187:LOC108883636
gene id: 8187:LOC108883636
uniprot id: A0A4W6EX03
names: Similarity
messages: Belongs to the RAPGEF2 family.

8187:zmp:0000000755
gene id: 8187:zmp:0000000755
uniprot id: A0A4W6CEN8
names: Similarity
messages: Belongs to the PACS family.

8187:map3k15
gene id: 8187:map3k15
uniprot id: A0A4W6BSR2
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8187:LOC108896760
gene id: 8187:LOC108896760
uniprot id: A0A4W6DX29
names: Similarity
messages: Belongs to the RBR family.

8187:ndst1b
gene id: 8187:ndst1b
uniprot id: A0A4W6CA65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

8187:anks1b
gene id: 8187:anks1b
uniprot id: A0A4W6FHB7
names: Subcellular Location Annotation
messages: Cytoplasm

8187:LOC108893723
gene id: 8187:LOC108893723
uniprot id: A0A4W6F5D2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

8187:LOC108884480
gene id: 8187:LOC108884480
uniprot id: A0A4W6E374
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8187:tmem131l
gene id: 8187:tmem131l
uniprot id: A0A4W6EUH6
names: Similarity
messages: Belongs to the TMEM131 family.

8187:mc2r
gene id: 8187:mc2r
uniprot id: A0A4W6EXT6
names: Subcellular Location Annotation
messages: Cell membrane

8187:fcer1g
gene id: 8187:fcer1g
uniprot id: A0A4W6D7Z8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:serpini1
gene id: 8187:serpini1
uniprot id: A0A4W6E5I7
names: Similarity
messages: Belongs to the serpin family.

8187:LOC108891831
gene id: 8187:LOC108891831
uniprot id: A0A4W6DQF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108885076
gene id: 8187:LOC108885076
uniprot id: A0A4W6BUL7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8187:LOC108892826
gene id: 8187:LOC108892826
uniprot id: A0A4W6F1U1
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8187:LOC108898086
gene id: 8187:LOC108898086
uniprot id: A0A4W6D7C0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

8187:atp8b2
gene id: 8187:atp8b2
uniprot id: A0A4W6FUB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8187:serpine1
gene id: 8187:serpine1
uniprot id: A0A4W6EF00
names: Similarity
messages: Belongs to the serpin family.

8187:arxa
gene id: 8187:arxa
uniprot id: A0A4W6CG41
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108886891
gene id: 8187:LOC108886891
uniprot id: A0A4W6DEZ0
names: Subunit
messages: Monomer.

8187:ren
gene id: 8187:ren
uniprot id: A0A4W6EKE5
names: Similarity
messages: Belongs to the peptidase A1 family.

8187:usp30
gene id: 8187:usp30
uniprot id: A0A4W6G9T5
names: Similarity
messages: Belongs to the peptidase C19 family.

8187:LOC108882131
gene id: 8187:LOC108882131
uniprot id: A0A4W6DF28
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

8187:chrm2a
gene id: 8187:chrm2a
uniprot id: A0A4W6C410
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8187:camk1da
gene id: 8187:camk1da
uniprot id: A0A4W6F7T8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:cldn15la
gene id: 8187:cldn15la
uniprot id: A0A4W6CLD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:fam135a
gene id: 8187:fam135a
uniprot id: A0A4W6EFS2
uniprot id: A0A4W6EGU0
names: Similarity
messages: Belongs to the FAM135 family.

8187:gabra1
gene id: 8187:gabra1
uniprot id: A0A4W6ENW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:nsg2
gene id: 8187:nsg2
uniprot id: A0A4W6EZK5
names: Similarity
messages: Belongs to the NSG family.

8187:sigmar1
gene id: 8187:sigmar1
uniprot id: A0A4W6C379
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle

8187:nrd1a
gene id: 8187:nrd1a
uniprot id: A0A4W6E837
names: Similarity
messages: Belongs to the peptidase M16 family.

8187:psmf1
gene id: 8187:psmf1
uniprot id: A0A4W6DCH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome inhibitor PI31 family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

8187:LOC108902191
gene id: 8187:LOC108902191
uniprot id: A0A4W6CJ80
names: Similarity
messages: Belongs to the SEC6 family.

8187:cdc123
gene id: 8187:cdc123
uniprot id: A0A4W6F6F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

8187:LOC108877417
gene id: 8187:LOC108877417
uniprot id: A0A4W6DIT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:kcnk10a
gene id: 8187:kcnk10a
uniprot id: A0A4W6DMU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8187:rps3
gene id: 8187:rps3
uniprot id: A0A4W6D3F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: spindle

8187:dad1
gene id: 8187:dad1
uniprot id: A0A4W6CUJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8187:LOC108900204
gene id: 8187:LOC108900204
uniprot id: A0A4W6EXI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8187:lrrc8da
gene id: 8187:lrrc8da
uniprot id: A0A4W6FFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8187:fgfrl1a
gene id: 8187:fgfrl1a
uniprot id: A0A4W6EEQ9
names: Subcellular Location Annotation
messages: Membrane

8187:scg3
gene id: 8187:scg3
uniprot id: A0A4W6CE70
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

8187:mus81
gene id: 8187:mus81
uniprot id: A0A4W6CFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

8187:pcnx4
gene id: 8187:pcnx4
uniprot id: A0A4W6FIY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

8187:mmp23bb
gene id: 8187:mmp23bb
uniprot id: A0A4W6BUY6
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108884424
gene id: 8187:LOC108884424
uniprot id: A0A4W6G6V4
names: Similarity
messages: Belongs to the REXO4 family.

8187:stx16
gene id: 8187:stx16
uniprot id: A0A4W6FWN4
names: Similarity
messages: Belongs to the syntaxin family.

8187:alox12
gene id: 8187:alox12
uniprot id: A0A4W6DK59
names: Caution
names: Cofactor
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108892837
gene id: 8187:LOC108892837
uniprot id: A0A4W6EX88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:camkk1a
gene id: 8187:camkk1a
uniprot id: A0A4W6EG09
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108883639
gene id: 8187:LOC108883639
uniprot id: A0A4W6F2N0
names: Similarity
messages: Belongs to the dynein intermediate chain family.

8187:LOC108883107
gene id: 8187:LOC108883107
uniprot id: A0A4W6ENP2
names: Similarity
messages: Belongs to the EVA1 family.

8187:dhx9
gene id: 8187:dhx9
uniprot id: A0A4W6CF28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Nucleus

8187:si:ch73-139j3.4
gene id: 8187:si:ch73-139j3.4
uniprot id: A0A4W6DKS0
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108890849
gene id: 8187:LOC108890849
uniprot id: A0A4W6D0N6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:exoc6b
gene id: 8187:exoc6b
uniprot id: A0A4W6CE14
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

8187:si:dkey-22n8.3
gene id: 8187:si:dkey-22n8.3
uniprot id: A0A4W6BT83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion

8187:coro7
gene id: 8187:coro7
uniprot id: A0A4W6BJE4
names: Similarity
messages: Belongs to the WD repeat coronin family.

8187:entpd5a
gene id: 8187:entpd5a
uniprot id: A0A4W6F2H3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8187:colgalt1a
gene id: 8187:colgalt1a
uniprot id: A0A4W6FSA7
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8187:si:dkey-246i14.3
gene id: 8187:si:dkey-246i14.3
uniprot id: A0A4W6FUK0
uniprot id: A0A4W6FVC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:tmem167b
gene id: 8187:tmem167b
uniprot id: A0A4W6C232
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:scml2
gene id: 8187:scml2
uniprot id: A0A4W6CH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

8187:vrk1
gene id: 8187:vrk1
uniprot id: A0A4W6FA49
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:fzd4
gene id: 8187:fzd4
uniprot id: A0A4W6F9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8187:dpp7
gene id: 8187:dpp7
uniprot id: A0A4W6FNI9
names: Similarity
messages: Belongs to the peptidase S28 family.

8187:exoc2
gene id: 8187:exoc2
uniprot id: A0A4W6F9S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

8187:LOC108902976
gene id: 8187:LOC108902976
uniprot id: A0A4W6BV66
names: Similarity
messages: Belongs to the globin family.

8187:LOC108887571
gene id: 8187:LOC108887571
uniprot id: A0A4W6FPD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8187:gem
gene id: 8187:gem
uniprot id: A0A4W6CI33
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8187:eny2
gene id: 8187:eny2
uniprot id: A0A4W6EAM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

8187:LOC108878924
gene id: 8187:LOC108878924
uniprot id: A0A4W6CU81
names: Similarity
messages: Belongs to the uridine kinase family.

8187:glceb
gene id: 8187:glceb
uniprot id: A0A4W6F6Y2
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

8187:mrpl32
gene id: 8187:mrpl32
uniprot id: A0A4W6EE44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

8187:ggnbp2
gene id: 8187:ggnbp2
uniprot id: A0A4W6ETB3
names: Function
messages: May be involved in spermatogenesis.

8187:wu:fa11c10
gene id: 8187:wu:fa11c10
uniprot id: A0A4W6BLI7
names: Similarity
messages: Belongs to the FAM110 family.

8187:LOC108875759
gene id: 8187:LOC108875759
uniprot id: A0A4W6FSV5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:LOC108897993
gene id: 8187:LOC108897993
uniprot id: A0A4W6DYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:avp
gene id: 8187:avp
uniprot id: A0A4W6CIG2
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

8187:lemd1
gene id: 8187:lemd1
uniprot id: A0A4W6DLQ7
uniprot id: A0A4W6DLV1
names: Similarity
messages: Belongs to the LEM family.

8187:lars2
gene id: 8187:lars2
uniprot id: A0A4W6CKC3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8187:adcy3a
gene id: 8187:adcy3a
uniprot id: A0A4W6C0C9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8187:crb2a
gene id: 8187:crb2a
uniprot id: A0A4W6DLV0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:fnip1
gene id: 8187:fnip1
uniprot id: A0A4W6DWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

8187:grk1a
gene id: 8187:grk1a
uniprot id: A0A4W6D7P3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8187:ccn5
gene id: 8187:ccn5
uniprot id: A0A4W6D3U9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:cdk21
gene id: 8187:cdk21
uniprot id: A0A4W6FJY0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:shox2
gene id: 8187:shox2
uniprot id: A0A4W6E373
names: Subcellular Location Annotation
messages: Nucleus

8187:pip4p1a
gene id: 8187:pip4p1a
uniprot id: A0A4W6BVX3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8187:emx1
gene id: 8187:emx1
uniprot id: A0A4W6DQJ1
names: Subcellular Location Annotation
messages: Nucleus

8187:myb
gene id: 8187:myb
uniprot id: A0A4W6E9Z4
names: Subcellular Location Annotation
messages: Nucleus

8187:gabra3
gene id: 8187:gabra3
uniprot id: A0A4W6F4B1
uniprot id: A0A4W6F4Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:wnt2bb
gene id: 8187:wnt2bb
uniprot id: A0A4W6DBW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:cept1b
gene id: 8187:cept1b
uniprot id: A0A4W6CAU4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8187:sf3b5
gene id: 8187:sf3b5
uniprot id: A0A4W6ESB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

8187:plin6
gene id: 8187:plin6
uniprot id: A0A4W6DSX4
names: Similarity
messages: Belongs to the perilipin family.

8187:nr1h4
gene id: 8187:nr1h4
uniprot id: A0A4W6EBC0
uniprot id: A0A4W6EBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8187:erf
gene id: 8187:erf
uniprot id: A0A4W6FBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:pofut1
gene id: 8187:pofut1
uniprot id: A0A4W6BXH1
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

8187:st3gal3b
gene id: 8187:st3gal3b
uniprot id: A0A4W6FCJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8187:scg2b
gene id: 8187:scg2b
uniprot id: A0A4W6E339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

8187:LOC108882765
gene id: 8187:LOC108882765
uniprot id: A0A4W6CD14
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

8187:cacng7a
gene id: 8187:cacng7a
uniprot id: A0A4W6FP51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

8187:med22
gene id: 8187:med22
uniprot id: A0A4W6G7Z7
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8187:LOC108893547
gene id: 8187:LOC108893547
uniprot id: A0A4W6DA08
names: Similarity
messages: Belongs to the splicing factor SR family.

8187:arv1
gene id: 8187:arv1
uniprot id: A0A4W6EPQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

8187:ift57
gene id: 8187:ift57
uniprot id: A0A4W6CLA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

8187:tcta
gene id: 8187:tcta
uniprot id: A0A4W6CGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: Membrane

8187:LOC108876571
gene id: 8187:LOC108876571
uniprot id: A0A4W6E0A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

8187:ret
gene id: 8187:ret
uniprot id: A0A4W6CY63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.

8187:nfrkb
gene id: 8187:nfrkb
uniprot id: A0A4W6CZI2
names: Subcellular Location Annotation
messages: Nucleus

8187:siah1
gene id: 8187:siah1
uniprot id: A0A4W6DFH3
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

8187:LOC108872934
gene id: 8187:LOC108872934
uniprot id: A0A4W6BL24
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:tut1
gene id: 8187:tut1
uniprot id: A0A4W6DEV7
names: Subcellular Location Annotation
messages: nucleolus

8187:dmrt2b
gene id: 8187:dmrt2b
uniprot id: A0A4W6FR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8187:kdm6bb
gene id: 8187:kdm6bb
uniprot id: A0A4W6F5G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

8187:ppip5k1a
gene id: 8187:ppip5k1a
uniprot id: A0A4W6C4A3
uniprot id: A0A4W6C9S3
uniprot id: A0A4W6CCK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

8187:got1
gene id: 8187:got1
uniprot id: A0A4W6CD41
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

8187:pdia6
gene id: 8187:pdia6
uniprot id: A0A4W6F6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

8187:LOC108874902
gene id: 8187:LOC108874902
uniprot id: A0A4W6CTK0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

8187:tbca
gene id: 8187:tbca
uniprot id: A0A4W6DD81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

8187:riox1
gene id: 8187:riox1
uniprot id: A0A4W6ELA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

8187:csnk1g2b
gene id: 8187:csnk1g2b
uniprot id: A0A4W6CST3
uniprot id: A0A4W6CSY4
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

8187:atpaf1
gene id: 8187:atpaf1
uniprot id: A0A4W6F8A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

8187:LOC108900169
gene id: 8187:LOC108900169
uniprot id: A0A4W6EKF5
uniprot id: A0A4W6EMS9
uniprot id: A0A4W6EMU6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8187:btg4
gene id: 8187:btg4
uniprot id: A0A4W6FKE8
names: Similarity
messages: Belongs to the BTG family.

8187:LOC108883754
gene id: 8187:LOC108883754
uniprot id: A0A4W6FKB6
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108894558
gene id: 8187:LOC108894558
uniprot id: A0A4W6CMC4
uniprot id: A0A4W6CME5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

8187:LOC108882871
gene id: 8187:LOC108882871
uniprot id: A0A4W6F8C8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane

8187:gsk3ab
gene id: 8187:gsk3ab
uniprot id: A0A4W6BIM7
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

8187:kxd1
gene id: 8187:kxd1
uniprot id: A0A4W6E4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

8187:dpep1
gene id: 8187:dpep1
uniprot id: A0A4W6EU12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

8187:lmf2a
gene id: 8187:lmf2a
uniprot id: A0A4W6DC19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

8187:LOC108879752
gene id: 8187:LOC108879752
uniprot id: A0A4W6DRE7
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8187:gab2
gene id: 8187:gab2
uniprot id: A0A4W6C969
names: Similarity
messages: Belongs to the GAB family.

8187:kcnc1b
gene id: 8187:kcnc1b
uniprot id: A0A4W6DBW0
uniprot id: A0A4W6DC94
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108897142
gene id: 8187:LOC108897142
uniprot id: A0A4W6DYC2
names: Similarity
messages: Belongs to the RRP1 family.

8187:map3k8
gene id: 8187:map3k8
uniprot id: A0A4W6C0N0
uniprot id: A0A4W6DRB2
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8187:cldnk
gene id: 8187:cldnk
uniprot id: A0A4W6FZV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:cmc4
gene id: 8187:cmc4
uniprot id: A0A4W6BIA2
names: Similarity
messages: Belongs to the CMC4 family.

8187:nono
gene id: 8187:nono
uniprot id: A0A4W6FRL5
names: Subcellular Location Annotation
messages: Nucleus speckle

8187:nsun3
gene id: 8187:nsun3
uniprot id: A0A4W6C938
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8187:gje1a
gene id: 8187:gje1a
uniprot id: A0A4W6EP43
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108873472
gene id: 8187:LOC108873472
uniprot id: A0A4W6EK51
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

8187:LOC108891644
gene id: 8187:LOC108891644
uniprot id: A0A4W6G699
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108891846
gene id: 8187:LOC108891846
uniprot id: A0A4W6BPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108880471
gene id: 8187:LOC108880471
uniprot id: A0A4W6EZM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8187:mrpl19
gene id: 8187:mrpl19
uniprot id: A0A4W6ERP9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

8187:cxxc4
gene id: 8187:cxxc4
uniprot id: A0A4W6C1V7
names: Subcellular Location Annotation
messages: Cytoplasm

8187:LOC108886805
gene id: 8187:LOC108886805
uniprot id: A0A4W6BRF4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:LOC108877058
gene id: 8187:LOC108877058
uniprot id: A0A4W6FKH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8187:dpagt1
gene id: 8187:dpagt1
uniprot id: A0A4W6BNL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:sf3a2
gene id: 8187:sf3a2
uniprot id: A0A4W6EBZ5
names: Similarity
messages: Belongs to the SF3A2 family.

8187:fubp1
gene id: 8187:fubp1
uniprot id: A0A4W6FVF6
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108890515
gene id: 8187:LOC108890515
uniprot id: A0A4W6EE45
names: Similarity
messages: Belongs to the TPD52 family.

8187:tnfrsf21
gene id: 8187:tnfrsf21
uniprot id: A0A4W6EX99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:rtf2
gene id: 8187:rtf2
uniprot id: A0A4W6E9J9
names: Similarity
messages: Belongs to the rtf2 family.

8187:LOC108884887
gene id: 8187:LOC108884887
uniprot id: A0A4W6BQE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

8187:LOC108877149
gene id: 8187:LOC108877149
uniprot id: A0A4W6E8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

8187:arfgef1
gene id: 8187:arfgef1
uniprot id: A0A4W6DV27
uniprot id: A0A4W6DXT6
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

8187:stx5a
gene id: 8187:stx5a
uniprot id: A0A4W6EUF9
names: Similarity
messages: Belongs to the syntaxin family.

8187:sh3bgrl
gene id: 8187:sh3bgrl
uniprot id: A0A4W6BR62
names: Similarity
messages: Belongs to the SH3BGR family.

8187:calhm6
gene id: 8187:calhm6
uniprot id: A0A4W6EJG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8187:supv3l1
gene id: 8187:supv3l1
uniprot id: A0A4W6FX58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

8187:tbl1xr1a
gene id: 8187:tbl1xr1a
uniprot id: A0A4W6EZK9
names: Similarity
messages: Belongs to the WD repeat EBI family.

8187:LOC108883574
gene id: 8187:LOC108883574
uniprot id: A0A4W6EB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:LOC108884479
gene id: 8187:LOC108884479
uniprot id: A0A4W6CXI9
names: Subcellular Location Annotation
messages: Nucleus

8187:tmc4
gene id: 8187:tmc4
uniprot id: A0A4W6D3Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8187:shbg
gene id: 8187:shbg
uniprot id: A0A4W6CUF5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:ube2kb
gene id: 8187:ube2kb
uniprot id: A0A4W6BTG0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:fam72a
gene id: 8187:fam72a
uniprot id: A0A4W6DPT5
names: Similarity
messages: Belongs to the FAM72 family.

8187:mcm10
gene id: 8187:mcm10
uniprot id: A0A4W6F434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

8187:ano10b
gene id: 8187:ano10b
uniprot id: A0A4W6EG88
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:mindy2
gene id: 8187:mindy2
uniprot id: A0A4W6DXV6
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

8187:LOC108897345
gene id: 8187:LOC108897345
uniprot id: A0A4W6CPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

8187:cdv3
gene id: 8187:cdv3
uniprot id: A0A4W6CVD3
uniprot id: A0A4W6EP69
names: Similarity
messages: Belongs to the CDV3 family.

8187:mpped2a
gene id: 8187:mpped2a
uniprot id: A0A4W6EFT8
names: Similarity
messages: Belongs to the UPF0046 family.

8187:gpc1b
gene id: 8187:gpc1b
uniprot id: A0A4W6E570
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8187:dennd5a
gene id: 8187:dennd5a
uniprot id: A0A4W6D3A2
uniprot id: A0A4W6D3I1
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:gabrb1
gene id: 8187:gabrb1
uniprot id: A0A4W6EU59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:LOC108883318
gene id: 8187:LOC108883318
uniprot id: A0A4W6BMC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:tspan11
gene id: 8187:tspan11
uniprot id: A0A4W6CAB5
uniprot id: A0A4W6CC20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:cpb1
gene id: 8187:cpb1
uniprot id: A0A4W6D8L6
names: Similarity
messages: Belongs to the peptidase M14 family.

8187:LOC108900232
gene id: 8187:LOC108900232
uniprot id: A0A4W6ET13
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

8187:nr4a2a
gene id: 8187:nr4a2a
uniprot id: A0A4W6FNZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8187:pex14
gene id: 8187:pex14
uniprot id: A0A4W6C6W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
messages: Peroxisome membrane

8187:prkcha
gene id: 8187:prkcha
uniprot id: A0A4W6FIQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

8187:tprkb
gene id: 8187:tprkb
uniprot id: A0A4W6E2H8
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

8187:gdpd3a
gene id: 8187:gdpd3a
uniprot id: A0A4W6BT63
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8187:trappc6bl
gene id: 8187:trappc6bl
uniprot id: A0A4W6D2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

8187:naa10
gene id: 8187:naa10
uniprot id: A0A4W6ERD3
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

8187:LOC108897265
gene id: 8187:LOC108897265
uniprot id: A0A4W6D7F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8187:drd4-rs
gene id: 8187:drd4-rs
uniprot id: A0A4W6DGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:kcnq2a
gene id: 8187:kcnq2a
uniprot id: A0A4W6CM20
uniprot id: A0A4W6CM32
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:ube2s
gene id: 8187:ube2s
uniprot id: A0A4W6D415
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:ppp1caa
gene id: 8187:ppp1caa
uniprot id: A0A4W6CDQ4
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

8187:LOC108875114
gene id: 8187:LOC108875114
uniprot id: A0A4W6G3N7
names: Similarity
messages: Belongs to the CFAP157 family.

8187:epgn
gene id: 8187:epgn
uniprot id: A0A4W6BR85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:si:ch73-141c7.1
gene id: 8187:si:ch73-141c7.1
uniprot id: A0A4W6CRD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8187:si:ch1073-513e17.1
gene id: 8187:si:ch1073-513e17.1
uniprot id: A0A4W6DSG0
names: Subcellular Location Annotation
messages: Membrane

8187:dynlt1b
gene id: 8187:dynlt1b
uniprot id: A0A4W6CJM8
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8187:ppp2r2d
gene id: 8187:ppp2r2d
uniprot id: A0A4W6D823
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8187:LOC108873743
gene id: 8187:LOC108873743
uniprot id: A0A4W6C9M2
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

8187:dbr1
gene id: 8187:dbr1
uniprot id: A0A4W6CZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

8187:aqp7
gene id: 8187:aqp7
uniprot id: A0A4W6CS59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8187:LOC108874440
gene id: 8187:LOC108874440
uniprot id: A0A4W6CN49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

8187:cds1
gene id: 8187:cds1
uniprot id: A0A4W6EET4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

8187:pla2g12a
gene id: 8187:pla2g12a
uniprot id: A0A4W6CH43
names: Subcellular Location Annotation
messages: Secreted

8187:LOC108874924
gene id: 8187:LOC108874924
uniprot id: A0A4W6EKK8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:slc35e3
gene id: 8187:slc35e3
uniprot id: A0A4W6C0A9
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108887954
gene id: 8187:LOC108887954
uniprot id: A0A4W6CF87
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108877744
gene id: 8187:LOC108877744
uniprot id: A0A4W6BSM1
names: Similarity
messages: Belongs to the RIPOR family.

8187:smad3b
gene id: 8187:smad3b
uniprot id: A0A4W6DP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8187:arf3b
gene id: 8187:arf3b
uniprot id: A0A4W6EI63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8187:LOC108878317
gene id: 8187:LOC108878317
uniprot id: A0A4W6G764
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

8187:tmem138
gene id: 8187:tmem138
uniprot id: A0A4W6DX59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

8187:pank4
gene id: 8187:pank4
uniprot id: A0A4W6EHV3
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

8187:gna14a
gene id: 8187:gna14a
uniprot id: A0A4W6GBL6
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8187:LOC108889933
gene id: 8187:LOC108889933
uniprot id: A0A4W6DQM7
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

8187:adgrl1a
gene id: 8187:adgrl1a
uniprot id: A0A4W6FSX5
names: Subcellular Location Annotation
messages: Membrane

8187:arvcfa
gene id: 8187:arvcfa
uniprot id: A0A4W6CMX9
names: Similarity
messages: Belongs to the beta-catenin family.

8187:cd9a
gene id: 8187:cd9a
uniprot id: A0A4W6D7M6
uniprot id: A0A4W6D7X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

8187:LOC108882854
gene id: 8187:LOC108882854
uniprot id: A0A4W6DES0
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

8187:LOC108888686
gene id: 8187:LOC108888686
uniprot id: A0A4W6EJ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8187:LOC108897008
gene id: 8187:LOC108897008
uniprot id: A0A4W6D3Q9
names: Similarity
messages: Belongs to the cornifelin family.

8187:LOC108896321
gene id: 8187:LOC108896321
uniprot id: A0A4W6DDW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

8187:ctnnbip1
gene id: 8187:ctnnbip1
uniprot id: A0A4W6C9L5
names: Similarity
messages: Belongs to the CTNNBIP1 family.

8187:b4galt4
gene id: 8187:b4galt4
uniprot id: A0A4W6CSN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8187:LOC108888586
gene id: 8187:LOC108888586
uniprot id: A0A4W6DWK6
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

8187:LOC108901754
gene id: 8187:LOC108901754
uniprot id: A0A4W6D258
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:niban2b
gene id: 8187:niban2b
uniprot id: A0A4W6FLK5
names: Similarity
messages: Belongs to the Niban family.

8187:insig2
gene id: 8187:insig2
uniprot id: A0A4W6DYN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

8187:yipf1
gene id: 8187:yipf1
uniprot id: A0A4W6EXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8187:spinb
gene id: 8187:spinb
uniprot id: A0A4W6DZ46
names: Similarity
messages: Belongs to the SPIN/STSY family.

8187:LOC108883549
gene id: 8187:LOC108883549
uniprot id: A0A4W6E823
uniprot id: A0A4W6E923
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

8187:lsm6
gene id: 8187:lsm6
uniprot id: A0A4W6EWN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

8187:opn3
gene id: 8187:opn3
uniprot id: A0A4W6D257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8187:LOC108895683
gene id: 8187:LOC108895683
uniprot id: A0A4W6CYM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

8187:LOC108897615
gene id: 8187:LOC108897615
uniprot id: A0A4W6EJ13
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:rxfp1
gene id: 8187:rxfp1
uniprot id: A0A4W6FEA4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108889630
gene id: 8187:LOC108889630
uniprot id: A0A4W6E1N1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:ctsl.1
gene id: 8187:ctsl.1
uniprot id: A0A4W6EQ93
names: Similarity
messages: Belongs to the peptidase C1 family.

8187:LOC108873765
gene id: 8187:LOC108873765
uniprot id: A0A4W6C0Q9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:pamr1a
gene id: 8187:pamr1a
uniprot id: A0A4W6EMR7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108892153
gene id: 8187:LOC108892153
uniprot id: A0A4W6DQ48
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:prox1a
gene id: 8187:prox1a
uniprot id: A0A4W6E2M5
names: Subcellular Location Annotation
messages: Nucleus

8187:gal3st1a
gene id: 8187:gal3st1a
uniprot id: A0A4W6GC74
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8187:hebp2
gene id: 8187:hebp2
uniprot id: A0A4W6D9D4
names: Similarity
messages: Belongs to the HEBP family.

8187:plcg1
gene id: 8187:plcg1
uniprot id: A0A4W6F895
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

8187:sox19b
gene id: 8187:sox19b
uniprot id: A0A4W6DMW3
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108878349
gene id: 8187:LOC108878349
uniprot id: A0A4W6DHI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:LOC108885368
gene id: 8187:LOC108885368
uniprot id: A0A4W6D3L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-III AFP family.
messages: Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth.
messages: Secreted

8187:pnrc2
gene id: 8187:pnrc2
uniprot id: A0A4W6C004
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108902585
gene id: 8187:LOC108902585
uniprot id: A0A4W6EEE9
names: Subcellular Location Annotation
messages: Nucleus

8187:si:ch211-282j22.3
gene id: 8187:si:ch211-282j22.3
uniprot id: A0A4W6C6S6
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8187:lsm12b
gene id: 8187:lsm12b
uniprot id: A0A4W6E3Z0
names: Similarity
messages: Belongs to the LSM12 family.

8187:pfdn6
gene id: 8187:pfdn6
uniprot id: A0A4W6FNY1
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

8187:cckar
gene id: 8187:cckar
uniprot id: A0A4W6CSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:usp14
gene id: 8187:usp14
uniprot id: A0A4W6C9V5
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

8187:LOC108892258
gene id: 8187:LOC108892258
uniprot id: A0A4W6DZ86
names: Subcellular Location Annotation
messages: Membrane

8187:reep2
gene id: 8187:reep2
uniprot id: A0A4W6CG63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8187:LOC108893207
gene id: 8187:LOC108893207
uniprot id: A0A4W6EYY2
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

8187:prickle1b
gene id: 8187:prickle1b
uniprot id: A0A4W6D696
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8187:gpx7
gene id: 8187:gpx7
uniprot id: A0A4W6CUC6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8187:LOC108894010
gene id: 8187:LOC108894010
uniprot id: A0A4W6F336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:castor2
gene id: 8187:castor2
uniprot id: A0A4W6CV08
names: Similarity
messages: Belongs to the GATS family.

8187:tollip
gene id: 8187:tollip
uniprot id: A0A4W6CZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

8187:strada
gene id: 8187:strada
uniprot id: A0A4W6CKU8
uniprot id: A0A4W6CKV8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

8187:LOC108873429
gene id: 8187:LOC108873429
uniprot id: A0A4W6E6C9
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

8187:cadm2a
gene id: 8187:cadm2a
uniprot id: A0A4W6DBC2
uniprot id: A0A4W6DCF1
uniprot id: A0A4W6DCR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nectin family.
messages: Membrane

8187:nr4a1
gene id: 8187:nr4a1
uniprot id: A0A4W6FB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:arglu1a
gene id: 8187:arglu1a
uniprot id: A0A4W6DQN7
names: Similarity
messages: Belongs to the UPF0430 family.

8187:LOC108890234
gene id: 8187:LOC108890234
uniprot id: A0A4W6CRK1
names: Subcellular Location Annotation
messages: extracellular space

8187:mrps11
gene id: 8187:mrps11
uniprot id: A0A4W6G4Z7
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

8187:LOC108895014
gene id: 8187:LOC108895014
uniprot id: A0A4W6CQ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

8187:LOC108872947
gene id: 8187:LOC108872947
uniprot id: A0A4W6FNQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8187:per2
gene id: 8187:per2
uniprot id: A0A4W6DLU4
uniprot id: A0A4W6DN22
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:yju2
gene id: 8187:yju2
uniprot id: A0A4W6DY16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

8187:ciao1
gene id: 8187:ciao1
uniprot id: A0A4W6G0S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

8187:tmem30b
gene id: 8187:tmem30b
uniprot id: A0A4W6EKR0
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8187:pih1d1
gene id: 8187:pih1d1
uniprot id: A0A4W6F4J5
names: Similarity
messages: Belongs to the PIH1 family.

8187:mcama
gene id: 8187:mcama
uniprot id: A0A4W6FYH2
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108876436
gene id: 8187:LOC108876436
uniprot id: A0A4W6EJM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8187:adamts1
gene id: 8187:adamts1
uniprot id: A0A4W6G4P7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:fam76b
gene id: 8187:fam76b
uniprot id: A0A4W6FVC8
names: Similarity
messages: Belongs to the FAM76 family.

8187:LOC108882731
gene id: 8187:LOC108882731
uniprot id: A0A4W6EKZ2
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

8187:ipo8
gene id: 8187:ipo8
uniprot id: A0A4W6EVQ3
uniprot id: A0A4W6EWJ9
names: Subcellular Location Annotation
messages: Cytoplasm

8187:sgsm1a
gene id: 8187:sgsm1a
uniprot id: A0A4W6GB04
names: Similarity
messages: Belongs to the RUTBC family.

8187:mocos
gene id: 8187:mocos
uniprot id: A0A4W6D1H5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

8187:LOC108891027
gene id: 8187:LOC108891027
uniprot id: A0A4W6D0Q3
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

8187:eif3s6ip
gene id: 8187:eif3s6ip
uniprot id: A0A4W6FEV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8187:LOC108890846
gene id: 8187:LOC108890846
uniprot id: A0A4W6EG51
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8187:slc15a4
gene id: 8187:slc15a4
uniprot id: A0A4W6FL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

8187:LOC108883078
gene id: 8187:LOC108883078
uniprot id: A0A4W6F8R5
names: Subcellular Location Annotation
messages: Nucleus

8187:eif3ea
gene id: 8187:eif3ea
uniprot id: A0A4W6E6Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

8187:ngfrb
gene id: 8187:ngfrb
uniprot id: A0A4W6DZI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:epha6
gene id: 8187:epha6
uniprot id: A0A4W6C919
names: Subcellular Location Annotation
messages: Membrane

8187:slc2a9l2
gene id: 8187:slc2a9l2
uniprot id: A0A4W6D471
uniprot id: A0A4W6D4B5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8187:LOC108898932
gene id: 8187:LOC108898932
uniprot id: A0A4W6FVF8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

8187:irf8
gene id: 8187:irf8
uniprot id: A0A4W6C837
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108879149
gene id: 8187:LOC108879149
uniprot id: A0A4W6DB33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:sh3rf1
gene id: 8187:sh3rf1
uniprot id: A0A4W6E3L5
uniprot id: A0A4W6E4Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

8187:cct3
gene id: 8187:cct3
uniprot id: A0A4W6DV20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8187:rapgef6
gene id: 8187:rapgef6
uniprot id: A0A4W6DWW3
names: Similarity
messages: Belongs to the RAPGEF2 family.

8187:gata4
gene id: 8187:gata4
uniprot id: A0A4W6D150
names: Subcellular Location Annotation
messages: Nucleus

8187:qrfprb
gene id: 8187:qrfprb
uniprot id: A0A4W6ETB4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:p3h2
gene id: 8187:p3h2
uniprot id: A0A4W6FGT4
names: Similarity
messages: Belongs to the leprecan family.

8187:vgll2a
gene id: 8187:vgll2a
uniprot id: A0A4W6EV70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

8187:faah2b
gene id: 8187:faah2b
uniprot id: A0A4W6D2H1
names: Similarity
messages: Belongs to the amidase family.

8187:rtn4ip1
gene id: 8187:rtn4ip1
uniprot id: A0A4W6C945
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8187:grb2b
gene id: 8187:grb2b
uniprot id: A0A4W6BP39
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

8187:LOC108873016
gene id: 8187:LOC108873016
uniprot id: A0A4W6F1R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

8187:si:cabz01093077.1
gene id: 8187:si:cabz01093077.1
uniprot id: A0A4W6EKF7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:kifc3
gene id: 8187:kifc3
uniprot id: A0A4W6CTV9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8187:aadac
gene id: 8187:aadac
uniprot id: A0A4W6C2P7
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8187:LOC108895731
gene id: 8187:LOC108895731
uniprot id: A0A4W6BTH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

8187:KEG24 p07
gene id: 8187:KEG24_p07
uniprot id: Q3IA70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

8187:gfm1
gene id: 8187:gfm1
uniprot id: A0A4W6CRK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

8187:si:dkeyp-97a10.3
gene id: 8187:si:dkeyp-97a10.3
uniprot id: A0A4W6BYD6
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108884372
gene id: 8187:LOC108884372
uniprot id: A0A4W6EX76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

8187:homeza
gene id: 8187:homeza
uniprot id: A0A4W6CPW6
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108883949
gene id: 8187:LOC108883949
uniprot id: A0A4W6CTB8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8187:gng3
gene id: 8187:gng3
uniprot id: A0A4W6F383
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8187:LOC108893731
gene id: 8187:LOC108893731
uniprot id: A0A4W6F748
names: Similarity
messages: Belongs to the PP2C family.

8187:spsb1
gene id: 8187:spsb1
uniprot id: A0A4W6CHI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

8187:foxk2b
gene id: 8187:foxk2b
uniprot id: A0A4W6CNG7
names: Subcellular Location Annotation
messages: Nucleus

8187:recql5
gene id: 8187:recql5
uniprot id: A0A4W6BXB0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

8187:ppib
gene id: 8187:ppib
uniprot id: A0A4W6C6R9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8187:slc25a40
gene id: 8187:slc25a40
uniprot id: A0A4W6BRM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:LOC108875928
gene id: 8187:LOC108875928
uniprot id: A0A4W6DK58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8187:LOC108900264
gene id: 8187:LOC108900264
uniprot id: A0A4W6CAM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8187:LOC108894293
gene id: 8187:LOC108894293
uniprot id: A0A4W6C8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:LOC108898613
gene id: 8187:LOC108898613
uniprot id: A0A4W6F2C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

8187:rrp7a
gene id: 8187:rrp7a
uniprot id: A0A4W6DNK5
names: Similarity
messages: Belongs to the RRP7 family.

8187:lcor
gene id: 8187:lcor
uniprot id: A0A4W6EKU4
names: Subcellular Location Annotation
messages: Nucleus

8187:rell1
gene id: 8187:rell1
uniprot id: A0A4W6E9N3
names: Similarity
messages: Belongs to the RELT family.

8187:LOC108895992
gene id: 8187:LOC108895992
uniprot id: A0A4W6FMH9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8187:LOC108900238
gene id: 8187:LOC108900238
uniprot id: A0A4W6F740
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8187:LOC108883880
gene id: 8187:LOC108883880
uniprot id: A0A4W6CAJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:ctnnd1
gene id: 8187:ctnnd1
uniprot id: A0A4W6DJX9
names: Similarity
messages: Belongs to the beta-catenin family.

8187:LOC108872703
gene id: 8187:LOC108872703
uniprot id: A0A4W6FU09
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

8187:b4gat1
gene id: 8187:b4gat1
uniprot id: A0A4W6DR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:dusp4
gene id: 8187:dusp4
uniprot id: A0A4W6BJ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8187:jph3a
gene id: 8187:jph3a
uniprot id: A0A4W6CBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:fam193a
gene id: 8187:fam193a
uniprot id: A0A4W6EWT0
names: Similarity
messages: Belongs to the FAM193 family.

8187:dhcr7
gene id: 8187:dhcr7
uniprot id: A0A4W6G0J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

8187:LOC108901656
gene id: 8187:LOC108901656
uniprot id: A0A4W6EUJ4
names: Subcellular Location Annotation
messages: Z line

8187:LOC108886462
gene id: 8187:LOC108886462
uniprot id: A0A4W6G3P4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:foxi1
gene id: 8187:foxi1
uniprot id: A0A4W6FDW6
names: Subcellular Location Annotation
messages: Nucleus

8187:taf4a
gene id: 8187:taf4a
uniprot id: A0A4W6F5V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8187:hoxa2b
gene id: 8187:hoxa2b
uniprot id: A0A4W6DJY7
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108888271
gene id: 8187:LOC108888271
uniprot id: A0A4W6C185
names: Similarity
messages: Belongs to the SPRN family.

8187:cog7
gene id: 8187:cog7
uniprot id: A0A4W6BRX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108887526
gene id: 8187:LOC108887526
uniprot id: A0A4W6FMW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8187:ap3s2
gene id: 8187:ap3s2
uniprot id: A0A4W6G323
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

8187:p2rx2
gene id: 8187:p2rx2
uniprot id: A0A4W6GC77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8187:gabrg1
gene id: 8187:gabrg1
uniprot id: A0A4W6DLT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:stard13a
gene id: 8187:stard13a
uniprot id: A0A4W6FEP6
uniprot id: A0A4W6FFJ4
uniprot id: A0A4W6FFJ9
names: Subcellular Location Annotation
messages: Cytoplasm

8187:anp32b
gene id: 8187:anp32b
uniprot id: A0A4W6BSK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

8187:atp23
gene id: 8187:atp23
uniprot id: A0A4W6D2R3
names: Similarity
messages: Belongs to the peptidase M76 family.

8187:pheta2
gene id: 8187:pheta2
uniprot id: A0A4W6CJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

8187:LOC108879747
gene id: 8187:LOC108879747
uniprot id: A0A4W6FQ94
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8187:csrnp1b
gene id: 8187:csrnp1b
uniprot id: A0A4W6D9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8187:LOC108873687
gene id: 8187:LOC108873687
uniprot id: A0A4W6CE66
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8187:chpfa
gene id: 8187:chpfa
uniprot id: A0A4W6DJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8187:slc35c2
gene id: 8187:slc35c2
uniprot id: A0A4W6G288
names: Subcellular Location Annotation
messages: Membrane

8187:miga1
gene id: 8187:miga1
uniprot id: A0A4W6FU08
names: Similarity
messages: Belongs to the mitoguardin family.

8187:tram1
gene id: 8187:tram1
uniprot id: A0A4W6DZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

8187:LOC108881728
gene id: 8187:LOC108881728
uniprot id: A0A4W6DL72
names: Similarity
messages: Belongs to the cystatin family.

8187:mtmr6
gene id: 8187:mtmr6
uniprot id: A0A4W6FT39
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8187:sqlea
gene id: 8187:sqlea
uniprot id: A0A4W6E008
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

8187:sfxn5a
gene id: 8187:sfxn5a
uniprot id: A0A4W6DT05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

8187:LOC108887191
gene id: 8187:LOC108887191
uniprot id: A0A4W6GA88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:psma4
gene id: 8187:psma4
uniprot id: A0A4W6C9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8187:bmpr1ba
gene id: 8187:bmpr1ba
uniprot id: A0A4W6GCQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8187:sema7a
gene id: 8187:sema7a
uniprot id: A0A4W6DH71
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:pik3cd
gene id: 8187:pik3cd
uniprot id: A0A4W6CFM5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8187:rnf7
gene id: 8187:rnf7
uniprot id: A0A4W6E876
names: Similarity
messages: Belongs to the RING-box family.

8187:LOC108884116
gene id: 8187:LOC108884116
uniprot id: A0A4W6CBD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

8187:s100a10a
gene id: 8187:s100a10a
uniprot id: A0A4W6FDQ8
names: Similarity
messages: Belongs to the S-100 family.

8187:slc24a5
gene id: 8187:slc24a5
uniprot id: A0A4W6C6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8187:atp5f1c
gene id: 8187:atp5f1c
uniprot id: A0A4W6D516
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

8187:eif2b1
gene id: 8187:eif2b1
uniprot id: A0A4W6DC62
uniprot id: A0A4W6DDQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

8187:slc30a6
gene id: 8187:slc30a6
uniprot id: A0A4W6BQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8187:trim54
gene id: 8187:trim54
uniprot id: A0A4W6DFD2
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

8187:uckl1b
gene id: 8187:uckl1b
uniprot id: A0A4W6DWD3
uniprot id: A0A4W6DY14
uniprot id: A0A4W6DY19
names: Similarity
messages: Belongs to the uridine kinase family.

8187:tenm4
gene id: 8187:tenm4
uniprot id: A0A4W6C8Z0
uniprot id: A0A4W6C917
uniprot id: A0A4W6CGW9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:slc25a10b
gene id: 8187:slc25a10b
uniprot id: A0A4W6DPN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:tm2d1
gene id: 8187:tm2d1
uniprot id: A0A4W6CYJ9
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108875689
gene id: 8187:LOC108875689
uniprot id: A0A4W6CKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

8187:tmem35
gene id: 8187:tmem35
uniprot id: A0A4W6ECI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

8187:LOC108900349
gene id: 8187:LOC108900349
uniprot id: A0A4W6BS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8187:arpin
gene id: 8187:arpin
uniprot id: A0A4W6ES11
names: Similarity
messages: Belongs to the Arpin family.

8187:hao1
gene id: 8187:hao1
uniprot id: A0A4W6DXA5
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

8187:mfng
gene id: 8187:mfng
uniprot id: A0A4W6E6D6
names: Subcellular Location Annotation
messages: Membrane

8187:mtmr1a
gene id: 8187:mtmr1a
uniprot id: A0A4W6E9W8
uniprot id: A0A4W6EBY2
uniprot id: A0A4W6ECB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8187:LOC108872986
gene id: 8187:LOC108872986
uniprot id: A0A4W6FP58
names: Similarity
messages: Belongs to the MAGUK family.

8187:atp6v1e1a
gene id: 8187:atp6v1e1a
uniprot id: A0A4W6BYH7
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

8187:iqsec1a
gene id: 8187:iqsec1a
uniprot id: A0A4W6EQB5
uniprot id: A0A4W6ETN0
uniprot id: A0A4W6ETP2
uniprot id: A0A4W6EUN1
uniprot id: A0A4W6EVU3
names: Similarity
messages: Belongs to the BRAG family.

8187:LOC108876687
gene id: 8187:LOC108876687
uniprot id: A0A4W6D8P4
names: Similarity
messages: Belongs to the MAP65/ASE1 family.

8187:hsd17b1
gene id: 8187:hsd17b1
uniprot id: A0A4W6CR99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Favors the reduction of estrogens and androgens. Uses preferentially NADH.

8187:LOC108873588
gene id: 8187:LOC108873588
uniprot id: A0A4W6CID8
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108889532
gene id: 8187:LOC108889532
uniprot id: A0A4W6DYP4
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

8187:gnb2
gene id: 8187:gnb2
uniprot id: A0A4W6BTJ9
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8187:si:ch1073-145m9.1
gene id: 8187:si:ch1073-145m9.1
uniprot id: A0A4W6CFV5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8187:phkb
gene id: 8187:phkb
uniprot id: A0A4W6G0W6
uniprot id: A0A4W6G2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

8187:def8
gene id: 8187:def8
uniprot id: A0A4W6C6N0
names: Similarity
messages: Belongs to the DEF8 family.

8187:actr3
gene id: 8187:actr3
uniprot id: A0A4W6E7B1
names: Similarity
messages: Belongs to the actin family.

8187:foxf1
gene id: 8187:foxf1
uniprot id: A0A4W6C2U0
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108888195
gene id: 8187:LOC108888195
uniprot id: A0A4W6EC55
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108888406
gene id: 8187:LOC108888406
uniprot id: A0A4W6D329
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108890957
gene id: 8187:LOC108890957
uniprot id: A0A4W6D299
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8187:stx12
gene id: 8187:stx12
uniprot id: A0A4W6CTE0
names: Similarity
messages: Belongs to the syntaxin family.

8187:tmem256
gene id: 8187:tmem256
uniprot id: A0A4W6E926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

8187:cacfd1
gene id: 8187:cacfd1
uniprot id: A0A4W6BT36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

8187:zgc:162707
gene id: 8187:zgc:162707
uniprot id: A0A4W6FJA2
names: Similarity
messages: Belongs to the UPF0524 family.

8187:vamp8
gene id: 8187:vamp8
uniprot id: A0A4W6G9F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8187:ptprub
gene id: 8187:ptprub
uniprot id: A0A4W6CQ36
uniprot id: A0A4W6CQH1
uniprot id: A0A4W6CQI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

8187:rap2c
gene id: 8187:rap2c
uniprot id: A0A4W6EWA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8187:LOC108885288
gene id: 8187:LOC108885288
uniprot id: A0A4W6CCF9
names: Similarity
messages: Belongs to the PAIP2 family.

8187:pde4ca
gene id: 8187:pde4ca
uniprot id: A0A4W6F6Z8
uniprot id: A0A4W6F7M5
uniprot id: A0A4W6F8T7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8187:sncb
gene id: 8187:sncb
uniprot id: A0A4W6CUF8
names: Similarity
messages: Belongs to the synuclein family.

8187:foxj3
gene id: 8187:foxj3
uniprot id: A0A4W6FMM1
names: Subcellular Location Annotation
messages: Nucleus

8187:chmp6b
gene id: 8187:chmp6b
uniprot id: A0A4W6FWC7
names: Similarity
messages: Belongs to the SNF7 family.

8187:tfb2m
gene id: 8187:tfb2m
uniprot id: A0A4W6G2E3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:tspan3a
gene id: 8187:tspan3a
uniprot id: A0A4W6CGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:LOC108885414
gene id: 8187:LOC108885414
uniprot id: A0A4W6DHD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8187:ces3
gene id: 8187:ces3
uniprot id: A0A4W6F4G0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8187:grik5
gene id: 8187:grik5
uniprot id: A0A4W6BPZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8187:ywhag2
gene id: 8187:ywhag2
uniprot id: A0A4W6DNV2
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8187:LOC108872979
gene id: 8187:LOC108872979
uniprot id: A0A4W6FNF2
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108900312
gene id: 8187:LOC108900312
uniprot id: A0A4W6DFE2
names: Similarity
messages: Belongs to the TENT family.

8187:dll4
gene id: 8187:dll4
uniprot id: A0A4W6ESZ5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8187:sdhaf3
gene id: 8187:sdhaf3
uniprot id: A0A4W6CK90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

8187:ptgir
gene id: 8187:ptgir
uniprot id: A0A4W6ESU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:dolk
gene id: 8187:dolk
uniprot id: A0A4W6BPT8
names: Similarity
messages: Belongs to the polyprenol kinase family.

8187:rassf1
gene id: 8187:rassf1
uniprot id: A0A4W6DM76
names: Subcellular Location Annotation
messages: cytoskeleton

8187:sema5a
gene id: 8187:sema5a
uniprot id: A0A4W6E6B0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108891018
gene id: 8187:LOC108891018
uniprot id: A0A4W6D0Q8
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

8187:idh1
gene id: 8187:idh1
uniprot id: A0A4W6D1V5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

8187:LOC108897292
gene id: 8187:LOC108897292
uniprot id: A0A4W6CR97
uniprot id: A0A4W6CRA3
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8187:rad52
gene id: 8187:rad52
uniprot id: A0A4W6DXT4
names: Similarity
messages: Belongs to the RAD52 family.

8187:LOC108882538
gene id: 8187:LOC108882538
uniprot id: A0A4W6G7E8
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

8187:bora
gene id: 8187:bora
uniprot id: A0A4W6DQV8
names: Similarity
messages: Belongs to the BORA family.

8187:lnpa
gene id: 8187:lnpa
uniprot id: A0A4W6E930
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

8187:ctss2.1
gene id: 8187:ctss2.1
uniprot id: A0A4W6C7N8
names: Similarity
messages: Belongs to the peptidase C1 family.

8187:LOC108887870
gene id: 8187:LOC108887870
uniprot id: A0A4W6BLQ2
names: Subcellular Location Annotation
messages: Nucleus

8187:adgrd1
gene id: 8187:adgrd1
uniprot id: A0A4W6FK82
names: Subcellular Location Annotation
messages: Membrane

8187:cacnb2a
gene id: 8187:cacnb2a
uniprot id: A0A4W6FID8
uniprot id: A0A4W6FKC6
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

8187:eif3k
gene id: 8187:eif3k
uniprot id: A0A4W6FTL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

8187:scube2
gene id: 8187:scube2
uniprot id: A0A4W6D0L8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:gja13.1
gene id: 8187:gja13.1
uniprot id: A0A4W6ET14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8187:LOC108883770
gene id: 8187:LOC108883770
uniprot id: A0A4W6FME1
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8187:kif13ba
gene id: 8187:kif13ba
uniprot id: A0A4W6G4Z4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8187:sema3e
gene id: 8187:sema3e
uniprot id: A0A4W6DFS7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:ndufaf2
gene id: 8187:ndufaf2
uniprot id: A0A4W6C5A0
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

8187:mapre1b
gene id: 8187:mapre1b
uniprot id: A0A4W6EWB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8187:grin2ab
gene id: 8187:grin2ab
uniprot id: A0A4W6CRW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

8187:LOC108885655
gene id: 8187:LOC108885655
uniprot id: A0A4W6FEH6
names: Similarity
messages: Belongs to the TAFA family.

8187:c8a
gene id: 8187:c8a
uniprot id: A0A4W6C0D8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:LOC108879202
gene id: 8187:LOC108879202
uniprot id: A0A4W6C0A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

8187:tbx15
gene id: 8187:tbx15
uniprot id: A0A4W6CNX8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8187:plcg2
gene id: 8187:plcg2
uniprot id: A0A4W6EXU7
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

8187:meox2a
gene id: 8187:meox2a
uniprot id: A0A4W6CHQ8
names: Subcellular Location Annotation
messages: Nucleus

8187:hs3st3b1a
gene id: 8187:hs3st3b1a
uniprot id: A0A4W6FZF8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:kmt5b
gene id: 8187:kmt5b
uniprot id: A0A4W6CD27
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8187:ern2
gene id: 8187:ern2
uniprot id: A0A4W6FYR7
names: Subcellular Location Annotation
messages: Membrane

8187:zc3h12b
gene id: 8187:zc3h12b
uniprot id: A0A4W6FC90
names: Similarity
messages: Belongs to the ZC3H12 family.

8187:tmx2b
gene id: 8187:tmx2b
uniprot id: A0A4W6FTY7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

8187:clmpb
gene id: 8187:clmpb
uniprot id: A0A4W6E9N8
names: Subcellular Location Annotation
messages: Membrane

8187:nudt2
gene id: 8187:nudt2
uniprot id: A0A4W6CT44
names: Similarity
messages: Belongs to the Nudix hydrolase family.

8187:ttc19
gene id: 8187:ttc19
uniprot id: A0A4W6CH80
names: Similarity
messages: Belongs to the TTC19 family.

8187:jph3b
gene id: 8187:jph3b
uniprot id: A0A4W6DZF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:ppargc1a
gene id: 8187:ppargc1a
uniprot id: A0A4W6EGJ6
names: Subcellular Location Annotation
messages: Nucleus

8187:dnm3b
gene id: 8187:dnm3b
uniprot id: A0A4W6BX31
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8187:cnot7
gene id: 8187:cnot7
uniprot id: A0A4W6BSE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8187:blm
gene id: 8187:blm
uniprot id: A0A4W6CGC0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

8187:aspa
gene id: 8187:aspa
uniprot id: A0A4W6EXY7
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

8187:LOC108879965
gene id: 8187:LOC108879965
uniprot id: A0A4W6CTM8
names: Subcellular Location Annotation
messages: Nucleus

8187:lrit1b
gene id: 8187:lrit1b
uniprot id: A0A4W6F593
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108899992
gene id: 8187:LOC108899992
uniprot id: A0A4W6DVJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

8187:fam219b
gene id: 8187:fam219b
uniprot id: A0A4W6G594
names: Similarity
messages: Belongs to the FAM219 family.

8187:fam136a
gene id: 8187:fam136a
uniprot id: A0A4W6BY43
names: Similarity
messages: Belongs to the FAM136 family.

8187:imp4
gene id: 8187:imp4
uniprot id: A0A4W6FPX2
names: Subcellular Location Annotation
messages: nucleolus

8187:zgc:65895
gene id: 8187:zgc:65895
uniprot id: A0A4W6DKM8
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8187:LOC108889672
gene id: 8187:LOC108889672
uniprot id: A0A4W6D096
names: Subcellular Location Annotation
messages: Nucleus

8187:rmnd1
gene id: 8187:rmnd1
uniprot id: A0A4W6ESN2
names: Similarity
messages: Belongs to the RMD1/sif2 family.

8187:psip1a
gene id: 8187:psip1a
uniprot id: A0A4W6CBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

8187:tp53rk
gene id: 8187:tp53rk
uniprot id: A0A4W6EB57
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

8187:arl2
gene id: 8187:arl2
uniprot id: A0A4W6ENM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8187:LOC108882115
gene id: 8187:LOC108882115
uniprot id: A0A4W6CD49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

8187:LOC108886205
gene id: 8187:LOC108886205
uniprot id: A0A4W6BZS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8187:smu1a
gene id: 8187:smu1a
uniprot id: A0A4W6CGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

8187:adra1d
gene id: 8187:adra1d
uniprot id: A0A4W6BZZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

8187:tmem121ab
gene id: 8187:tmem121ab
uniprot id: A0A4W6EGE1
names: Similarity
messages: Belongs to the TMEM121 family.

8187:LOC108902181
gene id: 8187:LOC108902181
uniprot id: A0A4W6EF11
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

8187:LOC108902719
gene id: 8187:LOC108902719
uniprot id: A0A4W6G2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

8187:c6
gene id: 8187:c6
uniprot id: A0A4W6E4X1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:rpl22l1
gene id: 8187:rpl22l1
uniprot id: A0A4W6FTK8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

8187:cmtm4
gene id: 8187:cmtm4
uniprot id: A0A4W6CI90
names: Subcellular Location Annotation
messages: Membrane

8187:tmem254
gene id: 8187:tmem254
uniprot id: A0A4W6G9N3
names: Subcellular Location Annotation
messages: Membrane

8187:tshba
gene id: 8187:tshba
uniprot id: A0A4W6CHI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8187:atf1
gene id: 8187:atf1
uniprot id: A0A4W6EHL9
names: Subcellular Location Annotation
messages: Nucleus

8187:pih1d2
gene id: 8187:pih1d2
uniprot id: A0A4W6G625
names: Similarity
messages: Belongs to the PIH1 family.

8187:wnt8b
gene id: 8187:wnt8b
uniprot id: A0A4W6D5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:parp12a
gene id: 8187:parp12a
uniprot id: A0A4W6F386
names: Similarity
messages: Belongs to the ARTD/PARP family.

8187:brms1lb
gene id: 8187:brms1lb
uniprot id: A0A4W6CB79
names: Subcellular Location Annotation
messages: Nucleus

8187:opn4xa
gene id: 8187:opn4xa
uniprot id: A0A4W6D1S6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108884514
gene id: 8187:LOC108884514
uniprot id: A0A4W6D107
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

8187:LOC108900193
gene id: 8187:LOC108900193
uniprot id: A0A4W6ENR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:LOC108887422
gene id: 8187:LOC108887422
uniprot id: A0A4W6G234
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8187:dimt1l
gene id: 8187:dimt1l
uniprot id: A0A4W6G9Z1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

8187:msrb3
gene id: 8187:msrb3
uniprot id: A0A4W6ELV5
uniprot id: A0A4W6ENT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

8187:LOC108898747
gene id: 8187:LOC108898747
uniprot id: A0A4W6C750
names: Subcellular Location Annotation
messages: Chromosome

8187:tmem184c
gene id: 8187:tmem184c
uniprot id: A0A4W6EUQ3
names: Subcellular Location Annotation
messages: Membrane

8187:cd44b
gene id: 8187:cd44b
uniprot id: A0A4W6EG23
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

8187:LOC108881515
gene id: 8187:LOC108881515
uniprot id: A0A4W6G020
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8187:skor1b
gene id: 8187:skor1b
uniprot id: A0A4W6DPF7
names: Similarity
messages: Belongs to the SKI family.

8187:osbpl8
gene id: 8187:osbpl8
uniprot id: A0A4W6E3F9
uniprot id: A0A4W6E510
uniprot id: A0A4W6E677
names: Similarity
messages: Belongs to the OSBP family.

8187:LOC108874422
gene id: 8187:LOC108874422
uniprot id: A0A4W6EY81
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8187:etv5a
gene id: 8187:etv5a
uniprot id: A0A4W6F0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:cant1a
gene id: 8187:cant1a
uniprot id: A0A4W6G0R0
names: Similarity
messages: Belongs to the apyrase family.

8187:vax2
gene id: 8187:vax2
uniprot id: A0A4W6D7S4
names: Subcellular Location Annotation
messages: Nucleus

8187:mgme1
gene id: 8187:mgme1
uniprot id: A0A4W6C0R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGME1 family.
messages: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair.
messages: Mitochondrion

8187:LOC108877345
gene id: 8187:LOC108877345
uniprot id: A0A4W6BRA7
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8187:gna12a
gene id: 8187:gna12a
uniprot id: A0A4W6FY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

8187:slc25a16
gene id: 8187:slc25a16
uniprot id: A0A4W6C578
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:LOC108895937
gene id: 8187:LOC108895937
uniprot id: A0A4W6FL01
names: Similarity
messages: Belongs to the peptidase C14A family.

8187:psma1
gene id: 8187:psma1
uniprot id: A0A4W6C4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8187:ptprn2
gene id: 8187:ptprn2
uniprot id: A0A4W6FJG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

8187:LOC108886019
gene id: 8187:LOC108886019
uniprot id: A0A4W6DCP5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

8187:plppr1
gene id: 8187:plppr1
uniprot id: A0A4W6G9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8187:ube2h
gene id: 8187:ube2h
uniprot id: A0A4W6FCI1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:zgc:171566
gene id: 8187:zgc:171566
uniprot id: A0A4W6G9A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

8187:mrpl43
gene id: 8187:mrpl43
uniprot id: A0A4W6BXN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

8187:s100s
gene id: 8187:s100s
uniprot id: A0A4W6FCX5
names: Similarity
messages: Belongs to the S-100 family.

8187:LOC108889496
gene id: 8187:LOC108889496
uniprot id: A0A4W6E7D6
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8187:LOC108895658
gene id: 8187:LOC108895658
uniprot id: A0A4W6D4C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8187:ssbp4
gene id: 8187:ssbp4
uniprot id: A0A4W6FRM0
names: Subcellular Location Annotation
messages: Nucleus

8187:nppb
gene id: 8187:nppb
uniprot id: A0A4W6CSL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8187:naprt
gene id: 8187:naprt
uniprot id: A0A4W6F8J3
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

8187:KEG24 t04
gene id: 8187:KEG24_t04
uniprot id: Q3IA76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

8187:slc8a4a
gene id: 8187:slc8a4a
uniprot id: A0A4W6F363
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8187:ddx1
gene id: 8187:ddx1
uniprot id: A0A4W6EIQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

8187:vegfd
gene id: 8187:vegfd
uniprot id: A0A4W6CF64
uniprot id: A0A4W6CGC9
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8187:LOC108881306
gene id: 8187:LOC108881306
uniprot id: A0A4W6FGM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8187:cpsf3
gene id: 8187:cpsf3
uniprot id: A0A4W6FZ26
names: Subcellular Location Annotation
messages: Nucleus

8187:tcirg1b
gene id: 8187:tcirg1b
uniprot id: A0A4W6C057
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8187:aste1b
gene id: 8187:aste1b
uniprot id: A0A4W6CNN9
names: Similarity
messages: Belongs to the asteroid family.

8187:cbfb
gene id: 8187:cbfb
uniprot id: A0A4W6DDS4
uniprot id: A0A4W6DEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

8187:nxph1
gene id: 8187:nxph1
uniprot id: A0A4W6CDC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8187:LOC108878814
gene id: 8187:LOC108878814
uniprot id: A0A4W6FTK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

8187:chmp2a
gene id: 8187:chmp2a
uniprot id: A0A4W6DZ89
names: Similarity
messages: Belongs to the SNF7 family.

8187:sox2
gene id: 8187:sox2
uniprot id: A0A4W6BVI3
names: Subcellular Location Annotation
messages: Nucleus

8187:irx4a
gene id: 8187:irx4a
uniprot id: A0A4W6EQY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8187:tafa4b
gene id: 8187:tafa4b
uniprot id: A0A4W6FCS3
names: Similarity
messages: Belongs to the TAFA family.

8187:LOC108884512
gene id: 8187:LOC108884512
uniprot id: A0A4W6BKC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

8187:LOC108878250
gene id: 8187:LOC108878250
uniprot id: A0A4W6BQH3
names: Similarity
messages: Belongs to the HARBI1 family.

8187:LOC108883616
gene id: 8187:LOC108883616
uniprot id: A0A4W6EK60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:nectin3b
gene id: 8187:nectin3b
uniprot id: A0A4W6FLC4
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108877021
gene id: 8187:LOC108877021
uniprot id: A0A4W6ELQ6
names: Similarity
messages: Belongs to the ARTD/PARP family.

8187:slc19a1
gene id: 8187:slc19a1
uniprot id: A0A4W6F1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

8187:LOC108896941
gene id: 8187:LOC108896941
uniprot id: A0A4W6DY55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8187:irf10
gene id: 8187:irf10
uniprot id: A0A4W6EUU5
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108888135
gene id: 8187:LOC108888135
uniprot id: A0A4W6FFC4
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8187:trim71
gene id: 8187:trim71
uniprot id: A0A4W6FPY7
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8187:nf2b
gene id: 8187:nf2b
uniprot id: A0A4W6FQ20
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8187:med20
gene id: 8187:med20
uniprot id: A0A4W6EMP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8187:lars1
gene id: 8187:lars1
uniprot id: A0A4W6EZN9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8187:LOC108879231
gene id: 8187:LOC108879231
uniprot id: A0A4W6C6V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8187:golt1a
gene id: 8187:golt1a
uniprot id: A0A4W6EA17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

8187:LOC108878944
gene id: 8187:LOC108878944
uniprot id: A0A4W6DDH0
names: Similarity
messages: Belongs to the TTC39 family.

8187:LOC108879031
gene id: 8187:LOC108879031
uniprot id: A0A4W6CYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:nup58
gene id: 8187:nup58
uniprot id: A0A4W6FT69
uniprot id: A0A4W6FUL1
names: Subcellular Location Annotation
messages: nuclear pore complex

8187:prozb
gene id: 8187:prozb
uniprot id: A0A4W6FTV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:hibadhb
gene id: 8187:hibadhb
uniprot id: A0A4W6DK11
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8187:mars2
gene id: 8187:mars2
uniprot id: A0A4W6BP64
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8187:si:dkey-25e12.3
gene id: 8187:si:dkey-25e12.3
uniprot id: A0A4W6D0K9
names: Similarity
messages: Belongs to the HINT family.

8187:srd5a2b
gene id: 8187:srd5a2b
uniprot id: A0A4W6CEI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

8187:tasor2
gene id: 8187:tasor2
uniprot id: A0A4W6F2X7
names: Similarity
messages: Belongs to the TASOR family.

8187:LOC108887189
gene id: 8187:LOC108887189
uniprot id: A0A4W6G986
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:nova1
gene id: 8187:nova1
uniprot id: A0A4W6DXC3
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

8187:LOC108898681
gene id: 8187:LOC108898681
uniprot id: A0A4W6EA88
uniprot id: A0A4W6EBD3
uniprot id: A0A4W6EBF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8187:notch2
gene id: 8187:notch2
uniprot id: A0A4W6FTT0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

8187:si:ch73-252i11.1
gene id: 8187:si:ch73-252i11.1
uniprot id: A0A4W6D3J7
names: Similarity
messages: Belongs to the ARTD/PARP family.

8187:LOC108872959
gene id: 8187:LOC108872959
uniprot id: A0A4W6G5G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8187:LOC108881486
gene id: 8187:LOC108881486
uniprot id: A0A4W6EIH3
names: Subcellular Location Annotation
messages: cytoskeleton

8187:mrc1b
gene id: 8187:mrc1b
uniprot id: A0A4W6EVF6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:wt1b
gene id: 8187:wt1b
uniprot id: A0A4W6CEY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

8187:cpz
gene id: 8187:cpz
uniprot id: A0A4W6E5W6
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:tmem170a
gene id: 8187:tmem170a
uniprot id: A0A4W6BMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

8187:pggt1b
gene id: 8187:pggt1b
uniprot id: A0A4W6BTM9
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

8187:egfl6
gene id: 8187:egfl6
uniprot id: A0A4W6CLW8
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:irf2bp2b
gene id: 8187:irf2bp2b
uniprot id: A0A4W6DJ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

8187:nlgn3b
gene id: 8187:nlgn3b
uniprot id: A0A4W6FS04
uniprot id: A0A4W6FT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8187:get4
gene id: 8187:get4
uniprot id: A0A4W6FAZ5
names: Similarity
messages: Belongs to the GET4 family.

8187:mrps7
gene id: 8187:mrps7
uniprot id: A0A4W6DXP3
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

8187:si:dkeyp-82a1.6
gene id: 8187:si:dkeyp-82a1.6
uniprot id: A0A4W6DHQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

8187:sult6b1
gene id: 8187:sult6b1
uniprot id: A0A4W6BRJ9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:scn1laa
gene id: 8187:scn1laa
uniprot id: A0A4W6G177
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

8187:cpo
gene id: 8187:cpo
uniprot id: A0A4W6E3E0
names: Similarity
messages: Belongs to the peptidase M14 family.

8187:prkcg
gene id: 8187:prkcg
uniprot id: A0A4W6D759
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

8187:LOC108899821
gene id: 8187:LOC108899821
uniprot id: A0A4W6DZF4
names: Subcellular Location Annotation
messages: Membrane

8187:atp5po
gene id: 8187:atp5po
uniprot id: A0A4W6E858
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

8187:timeless
gene id: 8187:timeless
uniprot id: A0A4W6F392
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

8187:ltb4r2b
gene id: 8187:ltb4r2b
uniprot id: A0A4W6BPM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:slc25a1a
gene id: 8187:slc25a1a
uniprot id: A0A4W6DB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:cpt1a2b
gene id: 8187:cpt1a2b
uniprot id: A0A4W6EPV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

8187:ydjc
gene id: 8187:ydjc
uniprot id: A0A4W6E6Z9
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

8187:poglut3
gene id: 8187:poglut3
uniprot id: A0A4W6ECN8
names: Similarity
messages: Belongs to the KDELC family.

8187:plin3
gene id: 8187:plin3
uniprot id: A0A4W6FUB0
names: Similarity
messages: Belongs to the perilipin family.

8187:syndig1l
gene id: 8187:syndig1l
uniprot id: A0A4W6EWC0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8187:vsig8b
gene id: 8187:vsig8b
uniprot id: A0A4W6F4X1
names: Subcellular Location Annotation
messages: Membrane

8187:etv4
gene id: 8187:etv4
uniprot id: A0A4W6G9U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:pax9
gene id: 8187:pax9
uniprot id: A0A4W6C0W2
names: Subcellular Location Annotation
messages: Nucleus

8187:tmem198b
gene id: 8187:tmem198b
uniprot id: A0A4W6ET60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8187:mpped1
gene id: 8187:mpped1
uniprot id: A0A4W6ETH5
names: Similarity
messages: Belongs to the UPF0046 family.

8187:rfx1b
gene id: 8187:rfx1b
uniprot id: A0A4W6CI94
names: Subcellular Location Annotation
messages: Nucleus

8187:rab3ip
gene id: 8187:rab3ip
uniprot id: A0A4W6BVD7
names: Similarity
messages: Belongs to the SEC2 family.

8187:LOC108901366
gene id: 8187:LOC108901366
uniprot id: A0A4W6D0E6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:LOC108884292
gene id: 8187:LOC108884292
uniprot id: A0A4W6CC46
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8187:pglyrp5
gene id: 8187:pglyrp5
uniprot id: A0A4W6G0T6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

8187:si:zfos-169g10.2
gene id: 8187:si:zfos-169g10.2
uniprot id: A0A4W6CWU0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:LOC108882539
gene id: 8187:LOC108882539
uniprot id: A0A4W6G6L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

8187:npb
gene id: 8187:npb
uniprot id: A0A4W6CBS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

8187:si:ch211-161c3.6
gene id: 8187:si:ch211-161c3.6
uniprot id: A0A4W6CEM4
names: Similarity
messages: Belongs to the HMGA family.

8187:LOC108898936
gene id: 8187:LOC108898936
uniprot id: A0A4W6FVQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:LOC108887592
gene id: 8187:LOC108887592
uniprot id: A0A4W6BP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8187:LOC108899549
gene id: 8187:LOC108899549
uniprot id: A0A4W6BS82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

8187:LOC108877643
gene id: 8187:LOC108877643
uniprot id: A0A4W6DFF7
names: Similarity
messages: Belongs to the BTG family.

8187:timm8b
gene id: 8187:timm8b
uniprot id: A0A4W6BYA6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8187:LOC108889801
gene id: 8187:LOC108889801
uniprot id: A0A4W6BQF4
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8187:myoc
gene id: 8187:myoc
uniprot id: A0A4W6CXU8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:olah
gene id: 8187:olah
uniprot id: A0A4W6EHR3
names: Similarity
messages: Belongs to the thioesterase family.

8187:cep55l
gene id: 8187:cep55l
uniprot id: A0A4W6CBR2
names: Subcellular Location Annotation
messages: Cytoplasm

8187:glyctk
gene id: 8187:glyctk
uniprot id: A0A4W6CGY1
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

8187:LOC108882932
gene id: 8187:LOC108882932
uniprot id: A0A4W6E3Q5
uniprot id: A0A4W6E7D9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8187:gpd1l
gene id: 8187:gpd1l
uniprot id: A0A4W6CIP9
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

8187:opn7b
gene id: 8187:opn7b
uniprot id: A0A4W6F9Z0
names: Subcellular Location Annotation
messages: Membrane

8187:antxr1b
gene id: 8187:antxr1b
uniprot id: A0A4W6CJJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8187:tm2d3
gene id: 8187:tm2d3
uniprot id: A0A4W6G6F3
names: Subcellular Location Annotation
messages: Membrane

8187:camk1a
gene id: 8187:camk1a
uniprot id: A0A4W6D7X3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:osbp
gene id: 8187:osbp
uniprot id: A0A4W6EK81
names: Similarity
messages: Belongs to the OSBP family.

8187:dpf2l
gene id: 8187:dpf2l
uniprot id: A0A4W6F4W5
names: Similarity
messages: Belongs to the requiem/DPF family.

8187:mnx1
gene id: 8187:mnx1
uniprot id: A0A4W6FI77
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108880474
gene id: 8187:LOC108880474
uniprot id: A0A4W6EXC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8187:cmbl
gene id: 8187:cmbl
uniprot id: A0A4W6CKK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

8187:LOC108898572
gene id: 8187:LOC108898572
uniprot id: A0A4W6CTA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

8187:LOC108900142
gene id: 8187:LOC108900142
uniprot id: A0A4W6DKU6
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:hnrnpaba
gene id: 8187:hnrnpaba
uniprot id: A0A4W6C8L9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:LOC108899833
gene id: 8187:LOC108899833
uniprot id: A0A4W6DXA8
names: Subcellular Location Annotation
messages: Membrane

8187:gys2
gene id: 8187:gys2
uniprot id: A0A4W6DDN8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

8187:caly
gene id: 8187:caly
uniprot id: A0A4W6D497
names: Similarity
messages: Belongs to the NSG family.

8187:LOC108898603
gene id: 8187:LOC108898603
uniprot id: A0A4W6F7Y7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8187:crhb
gene id: 8187:crhb
uniprot id: A0A4W6DS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

8187:LOC108900690
gene id: 8187:LOC108900690
uniprot id: A0A4W6BTT5
names: Subcellular Location Annotation
messages: Membrane

8187:pou4f1
gene id: 8187:pou4f1
uniprot id: A0A4W6D1J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8187:LOC108886467
gene id: 8187:LOC108886467
uniprot id: A0A4W6G314
names: Similarity
messages: Belongs to the peptidase A1 family.

8187:jak1
gene id: 8187:jak1
uniprot id: A0A4W6DA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

8187:zgc:162730
gene id: 8187:zgc:162730
uniprot id: A0A4W6D2H0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8187:acsf3
gene id: 8187:acsf3
uniprot id: A0A4W6CIZ1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8187:LOC108893974
gene id: 8187:LOC108893974
uniprot id: A0A4W6BZN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8187:tmx2a
gene id: 8187:tmx2a
uniprot id: A0A4W6EQ66
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

8187:tpte
gene id: 8187:tpte
uniprot id: A0A4W6DD03
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8187:hspb8
gene id: 8187:hspb8
uniprot id: A0A4W6E981
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8187:ogdha
gene id: 8187:ogdha
uniprot id: A0A4W6E2B5
uniprot id: A0A4W6E2C5
uniprot id: A0A4W6E2F6
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

8187:stmn1b
gene id: 8187:stmn1b
uniprot id: A0A4W6CKU3
names: Similarity
messages: Belongs to the stathmin family.

8187:mrps18c
gene id: 8187:mrps18c
uniprot id: A0A4W6DC34
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS18 family.

8187:clul1
gene id: 8187:clul1
uniprot id: A0A4W6EZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

8187:phtf1
gene id: 8187:phtf1
uniprot id: A0A4W6CU37
names: Subcellular Location Annotation
messages: Membrane

8187:rln3b
gene id: 8187:rln3b
uniprot id: A0A4W6CJP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8187:gnsb
gene id: 8187:gnsb
uniprot id: A0A4W6EU23
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8187:vps52
gene id: 8187:vps52
uniprot id: A0A4W6F164
names: Similarity
messages: Belongs to the VPS52 family.

8187:LOC108896979
gene id: 8187:LOC108896979
uniprot id: A0A4W6D481
names: Similarity
messages: Belongs to the cornifelin family.

8187:vps33b
gene id: 8187:vps33b
uniprot id: A0A4W6BSZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8187:pdxp
gene id: 8187:pdxp
uniprot id: A0A4W6CBR0
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

8187:ckmt1
gene id: 8187:ckmt1
uniprot id: A0A4W6FVQ6
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8187:paqr8
gene id: 8187:paqr8
uniprot id: A0A4W6CI50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8187:LOC108902924
gene id: 8187:LOC108902924
uniprot id: A0A4W6BVQ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8187:bckdk
gene id: 8187:bckdk
uniprot id: A0A4W6BIY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8187:tpp1
gene id: 8187:tpp1
uniprot id: A0A4W6FRC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:fam199x
gene id: 8187:fam199x
uniprot id: A0A4W6FV74
names: Similarity
messages: Belongs to the FAM199 family.

8187:ppdpfb
gene id: 8187:ppdpfb
uniprot id: A0A4W6G2H7
names: Similarity
messages: Belongs to the PPDPF family.

8187:mtmr3
gene id: 8187:mtmr3
uniprot id: A0A4W6G6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

8187:pdia2
gene id: 8187:pdia2
uniprot id: A0A4W6EPY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8187:mrps17
gene id: 8187:mrps17
uniprot id: A0A4W6F963
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8187:LOC108883840
gene id: 8187:LOC108883840
uniprot id: A0A4W6BWC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:tm9sf1
gene id: 8187:tm9sf1
uniprot id: A0A4W6D526
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8187:nampt2
gene id: 8187:nampt2
uniprot id: A0A4W6BUF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

8187:acaa1
gene id: 8187:acaa1
uniprot id: A0A4W6DKT8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8187:pigf
gene id: 8187:pigf
uniprot id: A0A4W6ELZ6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108883650
gene id: 8187:LOC108883650
uniprot id: A0A4W6F6N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

8187:clstn2a
gene id: 8187:clstn2a
uniprot id: A0A4W6F6U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

8187:si:ch211-269e2.1
gene id: 8187:si:ch211-269e2.1
uniprot id: A0A4W6DFM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

8187:fzd2
gene id: 8187:fzd2
uniprot id: A0A4W6CQV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:dgat1a
gene id: 8187:dgat1a
uniprot id: A0A4W6C2D7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

8187:LOC108874061
gene id: 8187:LOC108874061
uniprot id: A0A4W6CF60
names: Subcellular Location Annotation
messages: Nucleus

8187:ppp6r2a
gene id: 8187:ppp6r2a
uniprot id: A0A4W6EAP6
names: Similarity
messages: Belongs to the SAPS family.

8187:ndufa6
gene id: 8187:ndufa6
uniprot id: A0A4W6DLM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8187:tp63
gene id: 8187:tp63
uniprot id: A0A4W6DMX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Nucleus

8187:hlfa
gene id: 8187:hlfa
uniprot id: A0A4W6CNE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8187:cluap1
gene id: 8187:cluap1
uniprot id: A0A4W6CME6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

8187:LOC108901608
gene id: 8187:LOC108901608
uniprot id: A0A4W6CJQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8187:nr6a1a
gene id: 8187:nr6a1a
uniprot id: A0A4W6G4T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:LOC108897744
gene id: 8187:LOC108897744
uniprot id: A0A4W6G4Q3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
messages: Nucleus
messages: Transcription factor.

8187:LOC108895483
gene id: 8187:LOC108895483
uniprot id: A0A4W6CWB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

8187:LOC108887324
gene id: 8187:LOC108887324
uniprot id: A0A4W6D933
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8187:casp7
gene id: 8187:casp7
uniprot id: A0A4W6C5D8
names: Similarity
messages: Belongs to the peptidase C14A family.

8187:mfsd4b
gene id: 8187:mfsd4b
uniprot id: A0A4W6BSW0
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108889377
gene id: 8187:LOC108889377
uniprot id: A0A4W6D982
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8187:aurkaip1
gene id: 8187:aurkaip1
uniprot id: A0A4W6DNT0
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

8187:cenpu
gene id: 8187:cenpu
uniprot id: A0A4W6G720
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

8187:ogg1
gene id: 8187:ogg1
uniprot id: A0A4W6ELN0
names: Similarity
messages: Belongs to the type-1 OGG1 family.

8187:LOC108878377
gene id: 8187:LOC108878377
uniprot id: A0A4W6F421
names: Subcellular Location Annotation
messages: Membrane

8187:wnt10b
gene id: 8187:wnt10b
uniprot id: A0A4W6F8M9
uniprot id: A0A4W6FBU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:chmp1a
gene id: 8187:chmp1a
uniprot id: A0A4W6EL83
names: Similarity
messages: Belongs to the SNF7 family.

8187:kcnj9
gene id: 8187:kcnj9
uniprot id: A0A4W6C3G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8187:LOC108887824
gene id: 8187:LOC108887824
uniprot id: A0A4W6EA38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8187:nol12
gene id: 8187:nol12
uniprot id: A0A4W6DNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

8187:epn2
gene id: 8187:epn2
uniprot id: A0A4W6BQ79
uniprot id: A0A4W6BXW1
names: Similarity
messages: Belongs to the epsin family.

8187:nr5a1b
gene id: 8187:nr5a1b
uniprot id: A0A4W6DM41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

8187:LOC108899269
gene id: 8187:LOC108899269
uniprot id: A0A4W6C1B2
names: Similarity
messages: Belongs to the apolipoprotein L family.

8187:hoxb1b
gene id: 8187:hoxb1b
uniprot id: A0A4W6E1S6
names: Subcellular Location Annotation
messages: Nucleus

8187:fxn
gene id: 8187:fxn
uniprot id: A0A4W6FLG9
names: Similarity
messages: Belongs to the frataxin family.

8187:LOC108873165
gene id: 8187:LOC108873165
uniprot id: A0A4W6EXS3
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8187:LOC108876545
gene id: 8187:LOC108876545
uniprot id: A0A4W6CHN7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8187:ddx61
gene id: 8187:ddx61
uniprot id: A0A4W6BPU0
names: Similarity
messages: Belongs to the DEAD box helicase family.

8187:rpl22
gene id: 8187:rpl22
uniprot id: A0A4W6EKF1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

8187:poc1bl
gene id: 8187:poc1bl
uniprot id: A0A4W6CUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8187:sgcb
gene id: 8187:sgcb
uniprot id: A0A4W6EBV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

8187:slc16a6b
gene id: 8187:slc16a6b
uniprot id: A0A4W6D441
names: Subcellular Location Annotation
messages: Membrane

8187:man1b1b
gene id: 8187:man1b1b
uniprot id: A0A4W6FND9
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8187:nif3l1
gene id: 8187:nif3l1
uniprot id: A0A4W6G5V5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

8187:aurka
gene id: 8187:aurka
uniprot id: A0A4W6CA18
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

8187:LOC108900966
gene id: 8187:LOC108900966
uniprot id: A0A4W6BVP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:tmem276a
gene id: 8187:tmem276a
uniprot id: A0A4W6D7Q8
names: Similarity
messages: Belongs to the TMEM178 family.

8187:paqr5b
gene id: 8187:paqr5b
uniprot id: A0A4W6BQ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8187:tubgcp2
gene id: 8187:tubgcp2
uniprot id: A0A4W6DZR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

8187:traf2b
gene id: 8187:traf2b
uniprot id: A0A4W6CVV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8187:phlda2
gene id: 8187:phlda2
uniprot id: A0A4W6ELN4
names: Subcellular Location Annotation
messages: Cytoplasm

8187:hcn2b
gene id: 8187:hcn2b
uniprot id: A0A4W6C6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8187:LOC108883634
gene id: 8187:LOC108883634
uniprot id: A0A4W6EW74
names: Subcellular Location Annotation
messages: cytoskeleton

8187:coq3
gene id: 8187:coq3
uniprot id: A0A4W6E3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

8187:zgc:153675
gene id: 8187:zgc:153675
uniprot id: A0A4W6CDJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

8187:mboat2b
gene id: 8187:mboat2b
uniprot id: A0A4W6FXX5
names: Subcellular Location Annotation
messages: Membrane

8187:mrps26
gene id: 8187:mrps26
uniprot id: A0A4W6DSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

8187:dtwd2
gene id: 8187:dtwd2
uniprot id: A0A4W6CWZ9
names: Similarity
messages: Belongs to the TDD superfamily. DTWD2 family.

8187:si:dkey-91i10.3
gene id: 8187:si:dkey-91i10.3
uniprot id: A0A4W6EMT7
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:lrrc8aa
gene id: 8187:lrrc8aa
uniprot id: A0A4W6BQG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8187:mrps14
gene id: 8187:mrps14
uniprot id: A0A4W6E038
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

8187:fnta
gene id: 8187:fnta
uniprot id: A0A4W6FU31
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

8187:ap1g1
gene id: 8187:ap1g1
uniprot id: A0A4W6E8X5
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8187:b9d1
gene id: 8187:b9d1
uniprot id: A0A4W6BV03
names: Subcellular Location Annotation
messages: cilium basal body

8187:rhbdf1a
gene id: 8187:rhbdf1a
uniprot id: A0A4W6BVV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

8187:wdr24
gene id: 8187:wdr24
uniprot id: A0A4W6G2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR24 family.
messages: Lysosome membrane

8187:lin7a
gene id: 8187:lin7a
uniprot id: A0A4W6C3Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8187:LOC108883868
gene id: 8187:LOC108883868
uniprot id: A0A4W6BWD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:vapb
gene id: 8187:vapb
uniprot id: A0A4W6E4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:s1pr5b
gene id: 8187:s1pr5b
uniprot id: A0A4W6FUQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108895451
gene id: 8187:LOC108895451
uniprot id: A0A4W6F2D2
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8187:srp19
gene id: 8187:srp19
uniprot id: A0A4W6DX64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

8187:atp6v1e1b
gene id: 8187:atp6v1e1b
uniprot id: A0A4W6FEC4
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

8187:elovl1b
gene id: 8187:elovl1b
uniprot id: A0A4W6DHV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

8187:LOC108887317
gene id: 8187:LOC108887317
uniprot id: A0A4W6D824
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

8187:cyyr1
gene id: 8187:cyyr1
uniprot id: A0A4W6G3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYYR1 family.
messages: Membrane

8187:nup93
gene id: 8187:nup93
uniprot id: A0A4W6DCR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

8187:stx3b
gene id: 8187:stx3b
uniprot id: A0A4W6DFU0
names: Similarity
messages: Belongs to the syntaxin family.

8187:zgc:101583
gene id: 8187:zgc:101583
uniprot id: A0A4W6BTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8187:lmx1bb
gene id: 8187:lmx1bb
uniprot id: A0A4W6FPB6
names: Subcellular Location Annotation
messages: Nucleus

8187:smad5
gene id: 8187:smad5
uniprot id: A0A4W6FSP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8187:miox
gene id: 8187:miox
uniprot id: A0A4W6DBR6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

8187:sec11a
gene id: 8187:sec11a
uniprot id: A0A4W6FPK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:drd1b
gene id: 8187:drd1b
uniprot id: A0A4W6EXW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:plex9.2
gene id: 8187:plex9.2
uniprot id: A0A4W6C0Y3
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

8187:slc25a35
gene id: 8187:slc25a35
uniprot id: A0A4W6BRH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:LOC108887580
gene id: 8187:LOC108887580
uniprot id: A0A4W6BM89
names: Subcellular Location Annotation
messages: Secreted

8187:LOC108876357
gene id: 8187:LOC108876357
uniprot id: A0A4W6G751
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8187:LOC108881961
gene id: 8187:LOC108881961
uniprot id: A0A4W6EQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:mpp7a
gene id: 8187:mpp7a
uniprot id: A0A4W6G7X2
names: Similarity
messages: Belongs to the MAGUK family.

8187:LOC108902785
gene id: 8187:LOC108902785
uniprot id: A0A4W6EXS4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:LOC108894959
gene id: 8187:LOC108894959
uniprot id: A0A4W6EGI8
names: Subcellular Location Annotation
messages: Cytoplasm

8187:numb
gene id: 8187:numb
uniprot id: A0A4W6D8Q7
uniprot id: A0A4W6D924
uniprot id: A0A4W6D9B9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

8187:lpar2a
gene id: 8187:lpar2a
uniprot id: A0A4W6FQD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

8187:slc35d1a
gene id: 8187:slc35d1a
uniprot id: A0A4W6CQW4
names: Subcellular Location Annotation
messages: Membrane

8187:thnsl2
gene id: 8187:thnsl2
uniprot id: A0A4W6DIH8
names: Similarity
messages: Belongs to the threonine synthase family.

8187:ssu72
gene id: 8187:ssu72
uniprot id: A0A4W6ESQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

8187:tceanc2
gene id: 8187:tceanc2
uniprot id: A0A4W6F0L8
names: Subcellular Location Annotation
messages: Nucleus

8187:pthlha
gene id: 8187:pthlha
uniprot id: A0A4W6F0E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8187:zgc:113363
gene id: 8187:zgc:113363
uniprot id: A0A4W6EJ39
names: Similarity
messages: Belongs to the MDFI family.

8187:rnf8
gene id: 8187:rnf8
uniprot id: A0A4W6ESU0
names: Similarity
messages: Belongs to the CHFR family.
messages: Belongs to the RNF8 family.

8187:LOC108890415
gene id: 8187:LOC108890415
uniprot id: A0A4W6CNI4
uniprot id: A0A4W6CNJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
messages: Nucleus matrix
messages: The LD (leucine and aspartate-rich) motif 3 mediates interaction with GIT1 and functions as a nuclear export signal.
messages: cytoskeleton
messages: focal adhesion

8187:chac1
gene id: 8187:chac1
uniprot id: A0A4W6EYB5
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

8187:serpina10b
gene id: 8187:serpina10b
uniprot id: A0A4W6FBW7
names: Similarity
messages: Belongs to the serpin family.

8187:LOC108894043
gene id: 8187:LOC108894043
uniprot id: A0A4W6CKV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8187:ccl19a.1
gene id: 8187:ccl19a.1
uniprot id: A0A4W6EG89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8187:LOC108886266
gene id: 8187:LOC108886266
uniprot id: A0A4W6DIJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

8187:mchr1a
gene id: 8187:mchr1a
uniprot id: A0A4W6FRQ7
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

8187:LOC108900932
gene id: 8187:LOC108900932
uniprot id: A0A4W6BVM0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8187:ccne2
gene id: 8187:ccne2
uniprot id: A0A4W6D412
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:smg8
gene id: 8187:smg8
uniprot id: A0A4W6DJZ7
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

8187:tut4
gene id: 8187:tut4
uniprot id: A0A4W6CTR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

8187:LOC108881176
gene id: 8187:LOC108881176
uniprot id: A0A4W6CBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:runx2b
gene id: 8187:runx2b
uniprot id: A0A4W6DD50
uniprot id: A0A4W6DDN5
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108894395
gene id: 8187:LOC108894395
uniprot id: A0A4W6EX58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

8187:fth1a
gene id: 8187:fth1a
uniprot id: G9BDB7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8187:rfc4
gene id: 8187:rfc4
uniprot id: A0A4W6FYF8
names: Similarity
messages: Belongs to the activator 1 small subunits family.

8187:agpat2
gene id: 8187:agpat2
uniprot id: A0A4W6F3C8
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

8187:kcnk5a
gene id: 8187:kcnk5a
uniprot id: A0A4W6C8B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8187:exoc5
gene id: 8187:exoc5
uniprot id: A0A4W6F2Q0
names: Similarity
messages: Belongs to the SEC10 family.

8187:psme2
gene id: 8187:psme2
uniprot id: A0A4W6G5Q6
names: Similarity
messages: Belongs to the PA28 family.

8187:LOC108901662
gene id: 8187:LOC108901662
uniprot id: A0A4W6ES92
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:gatm
gene id: 8187:gatm
uniprot id: A0A4W6CH75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development.
messages: Homodimer.
messages: Mitochondrion inner membrane

8187:gbx2
gene id: 8187:gbx2
uniprot id: A0A4W6C4L2
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108902641
gene id: 8187:LOC108902641
uniprot id: A0A4W6G3I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

8187:gtf2f1
gene id: 8187:gtf2f1
uniprot id: A0A4W6EAY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

8187:pth4
gene id: 8187:pth4
uniprot id: A0A4W6CH09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8187:LOC108875058
gene id: 8187:LOC108875058
uniprot id: A0A4W6DZE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8187:nkx2.3
gene id: 8187:nkx2.3
uniprot id: A0A4W6C492
names: Subcellular Location Annotation
messages: Nucleus

8187:atxn3
gene id: 8187:atxn3
uniprot id: A0A4W6FBS7
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108874748
gene id: 8187:LOC108874748
uniprot id: A0A4W6D3G9
names: Similarity
messages: Belongs to the MS4A family.

8187:LOC108891881
gene id: 8187:LOC108891881
uniprot id: A0A4W6FJ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:pex19
gene id: 8187:pex19
uniprot id: A0A4W6BS43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

8187:insra
gene id: 8187:insra
uniprot id: A0A4W6EB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

8187:ankrd34c
gene id: 8187:ankrd34c
uniprot id: A0A4W6CJ62
names: Similarity
messages: Belongs to the ANKRD34 family.

8187:wdr83os
gene id: 8187:wdr83os
uniprot id: A0A4W6EHB7
names: Similarity
messages: Belongs to the Asterix family.

8187:elovl1a
gene id: 8187:elovl1a
uniprot id: A0A4W6DU83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

8187:tsc22d3
gene id: 8187:tsc22d3
uniprot id: A0A4W6DHY2
uniprot id: A0A4W6DIA2
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8187:sox14
gene id: 8187:sox14
uniprot id: A0A4W6D0H1
names: Subcellular Location Annotation
messages: Nucleus

8187:lipia
gene id: 8187:lipia
uniprot id: A0A4W6CUZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

8187:wdr44
gene id: 8187:wdr44
uniprot id: A0A4W6CEW8
names: Subcellular Location Annotation
messages: trans-Golgi network

8187:sirt4
gene id: 8187:sirt4
uniprot id: A0A4W6D6V2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

8187:LOC108892456
gene id: 8187:LOC108892456
uniprot id: A0A4W6DT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8187:dennd10
gene id: 8187:dennd10
uniprot id: A0A4W6D154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

8187:LOC108892184
gene id: 8187:LOC108892184
uniprot id: A0A4W6BQ25
names: Subcellular Location Annotation
messages: Nucleus

8187:cetp
gene id: 8187:cetp
uniprot id: A0A4W6ETR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.
messages: Secreted

8187:mrpl42
gene id: 8187:mrpl42
uniprot id: A0A4W6CM06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

8187:ndufaf7
gene id: 8187:ndufaf7
uniprot id: A0A4W6DEY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

8187:ndufb4
gene id: 8187:ndufb4
uniprot id: A0A4W6F7S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8187:agtr1b
gene id: 8187:agtr1b
uniprot id: A0A4W6D9M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

8187:atp10b
gene id: 8187:atp10b
uniprot id: A0A4W6E430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8187:hs2st1b
gene id: 8187:hs2st1b
uniprot id: A0A4W6CZR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108898597
gene id: 8187:LOC108898597
uniprot id: A0A4W6F7V3
names: Similarity
messages: Belongs to the tachykinin family.

8187:cfl1l
gene id: 8187:cfl1l
uniprot id: A0A4W6C2J8
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8187:LOC108875166
gene id: 8187:LOC108875166
uniprot id: A0A4W6DPF5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8187:LOC108880947
gene id: 8187:LOC108880947
uniprot id: A0A4W6CN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

8187:LOC108897329
gene id: 8187:LOC108897329
uniprot id: A0A4W6DR37
names: Subcellular Location Annotation
messages: Membrane

8187:slc25a37
gene id: 8187:slc25a37
uniprot id: A0A4W6GA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:psmc1b
gene id: 8187:psmc1b
uniprot id: A0A4W6C4N6
names: Similarity
messages: Belongs to the AAA ATPase family.

8187:tma16
gene id: 8187:tma16
uniprot id: A0A4W6EMW5
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

8187:adkb
gene id: 8187:adkb
uniprot id: A0A4W6BZX6
uniprot id: A0A4W6C235
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

8187:ide
gene id: 8187:ide
uniprot id: A0A4W6D336
names: Similarity
messages: Belongs to the peptidase M16 family.

8187:nagk
gene id: 8187:nagk
uniprot id: A0A4W6EHY3
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

8187:LOC108876645
gene id: 8187:LOC108876645
uniprot id: A0A4W6DPF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.

8187:kpnb1
gene id: 8187:kpnb1
uniprot id: A0A4W6C8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

8187:barx1
gene id: 8187:barx1
uniprot id: A0A4W6D1S9
names: Subcellular Location Annotation
messages: Nucleus

8187:fam174b
gene id: 8187:fam174b
uniprot id: A0A4W6CFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

8187:tnfsf10l
gene id: 8187:tnfsf10l
uniprot id: A0A4W6FR26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8187:rhbdf1b
gene id: 8187:rhbdf1b
uniprot id: A0A4W6G936
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

8187:LOC108894059
gene id: 8187:LOC108894059
uniprot id: A0A4W6FQU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:fh
gene id: 8187:fh
uniprot id: A0A4W6G3W2
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

8187:cebpa
gene id: 8187:cebpa
uniprot id: A0A4W6CV69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

8187:LOC108899811
gene id: 8187:LOC108899811
uniprot id: A0A4W6DYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8187:greb1
gene id: 8187:greb1
uniprot id: A0A4W6FWR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

8187:LOC108894820
gene id: 8187:LOC108894820
uniprot id: A0A4W6BXP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

8187:LOC108901638
gene id: 8187:LOC108901638
uniprot id: A0A4W6CLU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108887913
gene id: 8187:LOC108887913
uniprot id: A0A4W6C8G4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:pcyt1aa
gene id: 8187:pcyt1aa
uniprot id: A0A4W6F3N5
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

8187:aimp2
gene id: 8187:aimp2
uniprot id: A0A4W6DUE8
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

8187:mrps33
gene id: 8187:mrps33
uniprot id: A0A4W6DTK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

8187:urod
gene id: 8187:urod
uniprot id: A0A4W6CW63
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

8187:atg16l1
gene id: 8187:atg16l1
uniprot id: A0A4W6BVR3
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

8187:LOC108888539
gene id: 8187:LOC108888539
uniprot id: A0A4W6EGW8
names: Similarity
messages: Belongs to the SOGA family.

8187:micos13
gene id: 8187:micos13
uniprot id: A0A4W6BZ03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

8187:hat1
gene id: 8187:hat1
uniprot id: A0A4W6FUD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

8187:LOC108877009
gene id: 8187:LOC108877009
uniprot id: A0A4W6FWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8187:lrig2
gene id: 8187:lrig2
uniprot id: A0A4W6D5T6
names: Subcellular Location Annotation
messages: Membrane

8187:tefa
gene id: 8187:tefa
uniprot id: A0A4W6G1L9
uniprot id: A0A4W6G259
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8187:LOC108899740
gene id: 8187:LOC108899740
uniprot id: A0A4W6FBI5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108900144
gene id: 8187:LOC108900144
uniprot id: A0A4W6DL74
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:syk
gene id: 8187:syk
uniprot id: A0A4W6DJJ4
uniprot id: A0A4W6DKH2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

8187:sema6e
gene id: 8187:sema6e
uniprot id: A0A4W6C7X2
uniprot id: A0A4W6C7X7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108897703
gene id: 8187:LOC108897703
uniprot id: A0A4W6G1T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

8187:LOC108897386
gene id: 8187:LOC108897386
uniprot id: A0A4W6BPV7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8187:LOC108884513
gene id: 8187:LOC108884513
uniprot id: A0A4W6D0S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8187:dnttip2
gene id: 8187:dnttip2
uniprot id: A0A4W6G2G0
names: Subcellular Location Annotation
messages: nucleolus

8187:kpna4
gene id: 8187:kpna4
uniprot id: A0A4W6BX05
names: Similarity
messages: Belongs to the importin alpha family.

8187:il12ba
gene id: 8187:il12ba
uniprot id: A0A4W6CRA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

8187:b3gat1a
gene id: 8187:b3gat1a
uniprot id: A0A4W6CUQ0
uniprot id: A0A4W6CUQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108882837
gene id: 8187:LOC108882837
uniprot id: A0A4W6D1G5
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Membrane

8187:LOC108883628
gene id: 8187:LOC108883628
uniprot id: A0A4W6ERS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8187:sv2ca
gene id: 8187:sv2ca
uniprot id: A0A4W6GBM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8187:hbbe2
gene id: 8187:hbbe2
uniprot id: A0A4W6G913
names: Similarity
messages: Belongs to the globin family.

8187:dnmt3ab
gene id: 8187:dnmt3ab
uniprot id: A0A4W6EWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

8187:LOC108885443
gene id: 8187:LOC108885443
uniprot id: A0A4W6DYQ0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8187:me1
gene id: 8187:me1
uniprot id: A0A4W6E426
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

8187:mnd1
gene id: 8187:mnd1
uniprot id: A0A4W6EUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

8187:LOC108885542
gene id: 8187:LOC108885542
uniprot id: A0A4W6EPU0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:LOC108901874
gene id: 8187:LOC108901874
uniprot id: A0A4W6DE98
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:acsl6
gene id: 8187:acsl6
uniprot id: A0A4W6E8V0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8187:cabz01093075.1
gene id: 8187:cabz01093075.1
uniprot id: A0A4W6EI17
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:mrpl23
gene id: 8187:mrpl23
uniprot id: A0A4W6EMP0
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

8187:slc34a1b
gene id: 8187:slc34a1b
uniprot id: A0A4W6C4F9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

8187:atp6v0e1
gene id: 8187:atp6v0e1
uniprot id: A0A4W6CTI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8187:sema3aa
gene id: 8187:sema3aa
uniprot id: A0A4W6CCE1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:mtmr2
gene id: 8187:mtmr2
uniprot id: A0A4W6FUC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8187:entpd5b
gene id: 8187:entpd5b
uniprot id: A0A4W6DM06
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8187:LOC108876843
gene id: 8187:LOC108876843
uniprot id: A0A4W6FWG9
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8187:lhfpl6
gene id: 8187:lhfpl6
uniprot id: A0A4W6C7V8
names: Subcellular Location Annotation
messages: Membrane

8187:efemp2a
gene id: 8187:efemp2a
uniprot id: A0A4W6EVV0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108878550
gene id: 8187:LOC108878550
uniprot id: A0A4W6G7U5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:dgke
gene id: 8187:dgke
uniprot id: A0A4W6DEM8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8187:ca14
gene id: 8187:ca14
uniprot id: A0A4W6FQH2
uniprot id: A0A4W6FRU1
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

8187:loxl1
gene id: 8187:loxl1
uniprot id: A0A4W6EMZ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8187:gcat
gene id: 8187:gcat
uniprot id: A0A4W6F1I3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8187:sft2d3
gene id: 8187:sft2d3
uniprot id: A0A4W6CG25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

8187:sv2a
gene id: 8187:sv2a
uniprot id: A0A4W6BVX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8187:gsdmeb
gene id: 8187:gsdmeb
uniprot id: A0A4W6DK10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

8187:gchfr
gene id: 8187:gchfr
uniprot id: A0A4W6DUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

8187:rom1a
gene id: 8187:rom1a
uniprot id: A0A4W6F0C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

8187:msx2b
gene id: 8187:msx2b
uniprot id: A0A4W6EYY1
names: Subcellular Location Annotation
messages: Nucleus

8187:oprd1b
gene id: 8187:oprd1b
uniprot id: A0A4W6CGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:ghrl
gene id: 8187:ghrl
uniprot id: A0A4W6ELW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Secreted

8187:ctu2
gene id: 8187:ctu2
uniprot id: A0A4W6DTD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

8187:LOC108883905
gene id: 8187:LOC108883905
uniprot id: A0A4W6C9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Late endosome

8187:tmco4
gene id: 8187:tmco4
uniprot id: A0A4W6CFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO4 family.
messages: Membrane

8187:fgf8b
gene id: 8187:fgf8b
uniprot id: A0A4W6C9Z3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:wnt2
gene id: 8187:wnt2
uniprot id: A0A4W6C0B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:prickle1a
gene id: 8187:prickle1a
uniprot id: A0A4W6FK78
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8187:eva1ba
gene id: 8187:eva1ba
uniprot id: A0A4W6C896
names: Similarity
messages: Belongs to the EVA1 family.

8187:hnf1ba
gene id: 8187:hnf1ba
uniprot id: A0A4W6DX11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

8187:ndufb9
gene id: 8187:ndufb9
uniprot id: A0A4W6FM67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8187:LOC108892750
gene id: 8187:LOC108892750
uniprot id: A0A4W6F658
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:snap25a
gene id: 8187:snap25a
uniprot id: A0A4W6CHY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

8187:papss1
gene id: 8187:papss1
uniprot id: A0A4W6C9Q5
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

8187:txlnbb
gene id: 8187:txlnbb
uniprot id: A0A4W6FRR2
names: Similarity
messages: Belongs to the taxilin family.

8187:amotl2b
gene id: 8187:amotl2b
uniprot id: A0A4W6DVC6
names: Similarity
messages: Belongs to the angiomotin family.

8187:spi1b
gene id: 8187:spi1b
uniprot id: A0A4W6EWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:sv2ba
gene id: 8187:sv2ba
uniprot id: A0A4W6G2T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8187:sumf1
gene id: 8187:sumf1
uniprot id: A0A4W6FF40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

8187:stmn2a
gene id: 8187:stmn2a
uniprot id: A0A4W6DS20
names: Similarity
messages: Belongs to the stathmin family.

8187:usp44
gene id: 8187:usp44
uniprot id: A0A4W6G3P0
names: Similarity
messages: Belongs to the peptidase C19 family.

8187:coro6
gene id: 8187:coro6
uniprot id: A0A4W6FN73
names: Similarity
messages: Belongs to the WD repeat coronin family.

8187:proza
gene id: 8187:proza
uniprot id: A0A4W6C042
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:mfsd5
gene id: 8187:mfsd5
uniprot id: A0A4W6FLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

8187:adamts3
gene id: 8187:adamts3
uniprot id: A0A4W6FGV0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:cftr
gene id: 8187:cftr
uniprot id: A0A4W6BS67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Membrane
messages: Recycling endosome membrane

8187:dnpep
gene id: 8187:dnpep
uniprot id: A0A4W6ETT6
uniprot id: A0A4W6EWX3
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

8187:ca16b
gene id: 8187:ca16b
uniprot id: A0A4W6D926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

8187:cenpv
gene id: 8187:cenpv
uniprot id: A0A4W6ER86
names: Similarity
messages: Belongs to the Gfa family.

8187:LOC108875225
gene id: 8187:LOC108875225
uniprot id: A0A4W6DWW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8187:tm7sf2
gene id: 8187:tm7sf2
uniprot id: A0A4W6F0N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

8187:dpf2
gene id: 8187:dpf2
uniprot id: A0A4W6BWU9
names: Similarity
messages: Belongs to the requiem/DPF family.

8187:ccdc86
gene id: 8187:ccdc86
uniprot id: A0A4W6CA03
names: Subcellular Location Annotation
messages: Nucleus

8187:ap4b1
gene id: 8187:ap4b1
uniprot id: A0A4W6E4P0
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8187:LOC108873859
gene id: 8187:LOC108873859
uniprot id: A0A4W6C9K5
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8187:tspo
gene id: 8187:tspo
uniprot id: A0A4W6D688
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

8187:LOC108893161
gene id: 8187:LOC108893161
uniprot id: A0A4W6EIQ1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

8187:LOC108887758
gene id: 8187:LOC108887758
uniprot id: A0A4W6EIY4
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

8187:LOC108882132
gene id: 8187:LOC108882132
uniprot id: A0A4W6DEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8187:lhpp
gene id: 8187:lhpp
uniprot id: A0A4W6F3S0
uniprot id: A0A4W6F5L4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8187:notum1a
gene id: 8187:notum1a
uniprot id: A0A4W6G0U1
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

8187:chrna1
gene id: 8187:chrna1
uniprot id: A0A4W6BT34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:hmgb1b
gene id: 8187:hmgb1b
uniprot id: A0A4W6DW79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

8187:LOC108889207
gene id: 8187:LOC108889207
uniprot id: A0A4W6BYJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8187:lsm14b
gene id: 8187:lsm14b
uniprot id: A0A4W6EVV8
names: Similarity
messages: Belongs to the LSM14 family.

8187:map3k12
gene id: 8187:map3k12
uniprot id: A0A4W6F3H9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: May be an activator of the JNK/SAPK pathway.

8187:il4i1
gene id: 8187:il4i1
uniprot id: A0A4W6CNU1
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8187:LOC108890493
gene id: 8187:LOC108890493
uniprot id: A0A4W6EFQ3
names: Similarity
messages: Belongs to the OSBP family.

8187:LOC108875652
gene id: 8187:LOC108875652
uniprot id: A0A4W6CJD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8187:tbc1d7
gene id: 8187:tbc1d7
uniprot id: A0A4W6F7R1
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

8187:LOC108890903
gene id: 8187:LOC108890903
uniprot id: A0A4W6FF79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

8187:LOC108902739
gene id: 8187:LOC108902739
uniprot id: A0A4W6G1R7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:ctnna2
gene id: 8187:ctnna2
uniprot id: A0A4W6C050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

8187:chrd
gene id: 8187:chrd
uniprot id: A0A4W6BQE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chordin family.
messages: Secreted

8187:ormdl3
gene id: 8187:ormdl3
uniprot id: A0A4W6DSA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8187:chs1
gene id: 8187:chs1
uniprot id: A0A4W6G2U1
names: Subcellular Location Annotation
messages: Membrane

8187:desi1a
gene id: 8187:desi1a
uniprot id: A0A4W6CID9
names: Similarity
messages: Belongs to the DeSI family.

8187:mrpl20
gene id: 8187:mrpl20
uniprot id: A0A4W6EPX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

8187:LOC108887959
gene id: 8187:LOC108887959
uniprot id: A0A4W6CK92
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8187:ywhaba
gene id: 8187:ywhaba
uniprot id: A0A4W6EV82
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8187:vars1
gene id: 8187:vars1
uniprot id: A0A4W6CDP5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8187:treh
gene id: 8187:treh
uniprot id: A0A4W6CHM4
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

8187:LOC108882657
gene id: 8187:LOC108882657
uniprot id: A0A4W6CXE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108873081
gene id: 8187:LOC108873081
uniprot id: A0A4W6DWA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8187:LOC108895420
gene id: 8187:LOC108895420
uniprot id: A0A4W6FTD0
names: Similarity
messages: Belongs to the RENT3 family.

8187:tnfrsf1b
gene id: 8187:tnfrsf1b
uniprot id: A0A4W6FL89
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:si:ch211-236l14.4
gene id: 8187:si:ch211-236l14.4
uniprot id: A0A4W6EKT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8187:sntb1
gene id: 8187:sntb1
uniprot id: A0A4W6C3J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

8187:LOC108883876
gene id: 8187:LOC108883876
uniprot id: A0A4W6C2K0
uniprot id: A0A4W6C8F0
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8187:sucla2
gene id: 8187:sucla2
uniprot id: A0A4W6DE91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

8187:fam193b
gene id: 8187:fam193b
uniprot id: A0A4W6DFV4
names: Similarity
messages: Belongs to the FAM193 family.

8187:tlr3
gene id: 8187:tlr3
uniprot id: A0A4W6EWF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8187:rbp4
gene id: 8187:rbp4
uniprot id: A0A4W6CJ84
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8187:ppp3r1a
gene id: 8187:ppp3r1a
uniprot id: A0A4W6DVQ7
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

8187:palld
gene id: 8187:palld
uniprot id: A0A4W6E2Y7
names: Subcellular Location Annotation
messages: Membrane

8187:dipk1a
gene id: 8187:dipk1a
uniprot id: A0A4W6CYX2
names: Similarity
messages: Belongs to the DIPK family.

8187:ahcyl1
gene id: 8187:ahcyl1
uniprot id: A0A4W6CJ30
uniprot id: A0A4W6CJ51
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

8187:fam83d
gene id: 8187:fam83d
uniprot id: A0A4W6EUU6
names: Similarity
messages: Belongs to the FAM83 family.

8187:fabp7a
gene id: 8187:fabp7a
uniprot id: A0A4W6ECB4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8187:LOC108896336
gene id: 8187:LOC108896336
uniprot id: A0A4W6CH74
names: Subcellular Location Annotation
messages: Nucleus

8187:fyna
gene id: 8187:fyna
uniprot id: A0A4W6EG33
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8187:LOC108885232
gene id: 8187:LOC108885232
uniprot id: A0A4W6FZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8187:LOC108875413
gene id: 8187:LOC108875413
uniprot id: A0A4W6E6P2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:LOC108872946
gene id: 8187:LOC108872946
uniprot id: A0A4W6G3E4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8187:hcrtr2
gene id: 8187:hcrtr2
uniprot id: A0A4W6G8W3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:ripor1
gene id: 8187:ripor1
uniprot id: A0A4W6BRB2
names: Similarity
messages: Belongs to the RIPOR family.

8187:LOC108896631
gene id: 8187:LOC108896631
uniprot id: A0A4W6BIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8187:ptgs1
gene id: 8187:ptgs1
uniprot id: A0A4W6ECP0
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:tmem183a
gene id: 8187:tmem183a
uniprot id: A0A4W6DJP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

8187:igdcc3
gene id: 8187:igdcc3
uniprot id: A0A4W6F1G1
uniprot id: A0A4W6F2B7
names: Subcellular Location Annotation
messages: Membrane

8187:mpg
gene id: 8187:mpg
uniprot id: A0A4W6C393
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

8187:pitx3
gene id: 8187:pitx3
uniprot id: A0A4W6FEQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8187:tulp3
gene id: 8187:tulp3
uniprot id: A0A4W6BWF2
uniprot id: A0A4W6BWG5
uniprot id: A0A4W6C3Y6
uniprot id: A0A4W6C4J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

8187:septin8a
gene id: 8187:septin8a
uniprot id: A0A4W6ENA4
uniprot id: A0A4W6ENA9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8187:LOC108897341
gene id: 8187:LOC108897341
uniprot id: A0A4W6D6E9
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

8187:fth1b
gene id: 8187:fth1b
uniprot id: A0A4W6DZ28
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8187:LOC108887893
gene id: 8187:LOC108887893
uniprot id: A0A4W6BYK1
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

8187:grem2a
gene id: 8187:grem2a
uniprot id: A0A4W6EH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

8187:si:dkey-199f5.8
gene id: 8187:si:dkey-199f5.8
uniprot id: A0A4W6BX72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8187:tbx5a
gene id: 8187:tbx5a
uniprot id: A0A4W6CK26
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8187:junbb
gene id: 8187:junbb
uniprot id: A0A4W6EXC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8187:dyrk3
gene id: 8187:dyrk3
uniprot id: A0A4W6DNB1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8187:mettl1
gene id: 8187:mettl1
uniprot id: A0A4W6F3V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

8187:LOC108880658
gene id: 8187:LOC108880658
uniprot id: A0A4W6CE16
names: Subcellular Location Annotation
messages: Membrane

8187:rtn2a
gene id: 8187:rtn2a
uniprot id: A0A4W6EU30
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:endou
gene id: 8187:endou
uniprot id: A0A4W6EM31
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8187:vegfaa
gene id: 8187:vegfaa
uniprot id: A0A4W6C7X4
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8187:LOC108873573
gene id: 8187:LOC108873573
uniprot id: A0A4W6CJ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

8187:hoxb4a
gene id: 8187:hoxb4a
uniprot id: A0A4W6C1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8187:atp5pd
gene id: 8187:atp5pd
uniprot id: A0A4W6G042
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

8187:cenpt
gene id: 8187:cenpt
uniprot id: A0A4W6E107
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus

8187:sgk2a
gene id: 8187:sgk2a
uniprot id: A0A4W6BTI8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108901729
gene id: 8187:LOC108901729
uniprot id: A0A4W6BNJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8187:igsf8
gene id: 8187:igsf8
uniprot id: A0A4W6EC22
names: Subcellular Location Annotation
messages: Membrane

8187:tnca
gene id: 8187:tnca
uniprot id: A0A4W6CV15
uniprot id: A0A4W6CV26
uniprot id: A0A4W6CV59
uniprot id: A0A4W6CVT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:zgc:163057
gene id: 8187:zgc:163057
uniprot id: A0A4W6GBX2
names: Similarity
messages: Belongs to the globin family.

8187:ccna2
gene id: 8187:ccna2
uniprot id: A0A4W6FZJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:ppp2r5eb
gene id: 8187:ppp2r5eb
uniprot id: A0A4W6CUN6
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8187:rbm15
gene id: 8187:rbm15
uniprot id: A0A4W6CE44
names: Similarity
messages: Belongs to the RRM Spen family.

8187:rab32b
gene id: 8187:rab32b
uniprot id: A0A4W6EYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8187:LOC108886664
gene id: 8187:LOC108886664
uniprot id: A0A4W6DV68
names: Subcellular Location Annotation
messages: Cytoplasm

8187:slc35f3b
gene id: 8187:slc35f3b
uniprot id: A0A4W6ECD9
uniprot id: A0A4W6EH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

8187:LOC108884960
gene id: 8187:LOC108884960
uniprot id: A0A4W6CN59
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8187:nppcl
gene id: 8187:nppcl
uniprot id: A0A4W6DDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

8187:rprd1b
gene id: 8187:rprd1b
uniprot id: A0A4W6BJ70
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

8187:rftn2
gene id: 8187:rftn2
uniprot id: A0A4W6CZ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

8187:dynlt5
gene id: 8187:dynlt5
uniprot id: A0A4W6FPY2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8187:mtrf1
gene id: 8187:mtrf1
uniprot id: A0A4W6DKS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

8187:stk39
gene id: 8187:stk39
uniprot id: A0A4W6FKM7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8187:maneal
gene id: 8187:maneal
uniprot id: A0A4W6C4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:zdhhc8b
gene id: 8187:zdhhc8b
uniprot id: A0A4W6ELU1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8187:tbpl1
gene id: 8187:tbpl1
uniprot id: A0A4W6E959
names: Similarity
messages: Belongs to the TBP family.

8187:arl8ba
gene id: 8187:arl8ba
uniprot id: A0A4W6CUT9
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8187:top3b
gene id: 8187:top3b
uniprot id: A0A4W6FPE9
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

8187:rab9a
gene id: 8187:rab9a
uniprot id: A0A4W6CLZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

8187:eif4a3
gene id: 8187:eif4a3
uniprot id: A0A4W6DI67
names: Similarity
messages: Belongs to the DEAD box helicase family.

8187:pbx1a
gene id: 8187:pbx1a
uniprot id: A0A4W6DJE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8187:mmp16b
gene id: 8187:mmp16b
uniprot id: A0A4W6BVW9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8187:snrpd3l
gene id: 8187:snrpd3l
uniprot id: A0A4W6CIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

8187:nusap1
gene id: 8187:nusap1
uniprot id: A0A4W6FCN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

8187:spty2d1
gene id: 8187:spty2d1
uniprot id: A0A4W6EHA9
names: Similarity
messages: Belongs to the SPT2 family.

8187:LOC108879860
gene id: 8187:LOC108879860
uniprot id: A0A4W6DTH6
uniprot id: A0A4W6DVS1
uniprot id: A0A4W6DVT1
names: Similarity
messages: Belongs to the TOM1 family.

8187:tmem184ba
gene id: 8187:tmem184ba
uniprot id: A0A4W6BJV9
names: Subcellular Location Annotation
messages: Membrane

8187:mpp1
gene id: 8187:mpp1
uniprot id: A0A4W6F597
names: Similarity
messages: Belongs to the MAGUK family.

8187:tub
gene id: 8187:tub
uniprot id: A0A4W6DN92
uniprot id: A0A4W6DPD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

8187:eif1
gene id: 8187:eif1
uniprot id: A0A4W6DF92
names: Similarity
messages: Belongs to the SUI1 family.

8187:mybl1
gene id: 8187:mybl1
uniprot id: A0A4W6DQJ8
names: Subcellular Location Annotation
messages: Nucleus

8187:tmco3
gene id: 8187:tmco3
uniprot id: A0A4W6D814
names: Subcellular Location Annotation
messages: Membrane

8187:pcolceb
gene id: 8187:pcolceb
uniprot id: A0A4W6E8E0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:hsbp1b
gene id: 8187:hsbp1b
uniprot id: A0A4W6C821
names: Similarity
messages: Belongs to the HSBP1 family.

8187:tbxtb
gene id: 8187:tbxtb
uniprot id: A0A4W6EAP7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8187:snx8a
gene id: 8187:snx8a
uniprot id: A0A4W6CPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8187:pou6f1
gene id: 8187:pou6f1
uniprot id: A0A4W6FGA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8187:trpc5a
gene id: 8187:trpc5a
uniprot id: A0A4W6EWI9
names: Subcellular Location Annotation
messages: Membrane

8187:gnpda1
gene id: 8187:gnpda1
uniprot id: A0A4W6E2H9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

8187:tomm22
gene id: 8187:tomm22
uniprot id: A0A4W6BJY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

8187:lrrc8ab
gene id: 8187:lrrc8ab
uniprot id: A0A4W6EEE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8187:LOC108875019
gene id: 8187:LOC108875019
uniprot id: A0A4W6F618
names: Similarity
messages: Belongs to the peptidase M20A family.

8187:trpv6
gene id: 8187:trpv6
uniprot id: A0A4W6D9H9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108896419
gene id: 8187:LOC108896419
uniprot id: A0A4W6GBJ8
names: Similarity
messages: Belongs to the HPF1 family.

8187:cdk18
gene id: 8187:cdk18
uniprot id: A0A4W6FHS8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:tpt1
gene id: 8187:tpt1
uniprot id: A0A4W6DIM8
names: Similarity
messages: Belongs to the TCTP family.

8187:adipor2
gene id: 8187:adipor2
uniprot id: A0A4W6EJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8187:tspan33a
gene id: 8187:tspan33a
uniprot id: A0A4W6FBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:LOC108888211
gene id: 8187:LOC108888211
uniprot id: A0A4W6CAQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:LOC108877256
gene id: 8187:LOC108877256
uniprot id: A0A4W6ED64
names: Subcellular Location Annotation
messages: Nucleus

8187:actr8
gene id: 8187:actr8
uniprot id: A0A4W6BX17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

8187:anxa13l
gene id: 8187:anxa13l
uniprot id: A0A4W6BWC4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8187:spc25
gene id: 8187:spc25
uniprot id: A0A4W6FKU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

8187:hao2
gene id: 8187:hao2
uniprot id: A0A4W6F064
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

8187:LOC108899683
gene id: 8187:LOC108899683
uniprot id: A0A4W6CRL5
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8187:csnk2a2a
gene id: 8187:csnk2a2a
uniprot id: A0A4W6CE96
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:hoxb3a
gene id: 8187:hoxb3a
uniprot id: A0A4W6CAX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8187:dact2
gene id: 8187:dact2
uniprot id: A0A4W6FCG5
names: Similarity
messages: Belongs to the dapper family.

8187:trappc4
gene id: 8187:trappc4
uniprot id: A0A4W6FY32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

8187:akt3a
gene id: 8187:akt3a
uniprot id: A0A4W6DN74
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8187:phka1a
gene id: 8187:phka1a
uniprot id: A0A4W6FMR6
uniprot id: A0A4W6FPV4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

8187:LOC108882585
gene id: 8187:LOC108882585
uniprot id: A0A4W6BPA6
names: Subcellular Location Annotation
messages: Membrane

8187:epha4l
gene id: 8187:epha4l
uniprot id: A0A4W6C438
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

8187:tdo2a
gene id: 8187:tdo2a
uniprot id: A0A4W6F954
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108878327
gene id: 8187:LOC108878327
uniprot id: A0A4W6FLC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8187:rpl7
gene id: 8187:rpl7
uniprot id: A0A4W6E202
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

8187:LOC108883638
gene id: 8187:LOC108883638
uniprot id: A0A4W6EXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8187:fxr2
gene id: 8187:fxr2
uniprot id: A0A4W6CYK1
uniprot id: A0A4W6CYL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule

8187:LOC108881017
gene id: 8187:LOC108881017
uniprot id: A0A4W6EMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

8187:pvalb9
gene id: 8187:pvalb9
uniprot id: A0A4W6CKD4
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8187:ppp3cb
gene id: 8187:ppp3cb
uniprot id: A0A4W6FSD2
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

8187:rpl37
gene id: 8187:rpl37
uniprot id: A0A4W6C1R9
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

8187:pus7l
gene id: 8187:pus7l
uniprot id: A0A4W6D6K8
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

8187:tsnare1
gene id: 8187:tsnare1
uniprot id: A0A4W6ES17
names: Similarity
messages: Belongs to the syntaxin family.

8187:vamp4
gene id: 8187:vamp4
uniprot id: A0A4W6CXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8187:grm8a
gene id: 8187:grm8a
uniprot id: A0A4W6D4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8187:LOC108886434
gene id: 8187:LOC108886434
uniprot id: A0A4W6CNS5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:gabrd
gene id: 8187:gabrd
uniprot id: A0A4W6G8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:cacng3b
gene id: 8187:cacng3b
uniprot id: A0A4W6C2L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8187:crk
gene id: 8187:crk
uniprot id: A0A4W6BQY7
names: Similarity
messages: Belongs to the CRK family.

8187:slc25a47a
gene id: 8187:slc25a47a
uniprot id: A0A4W6ET08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:LOC108876541
gene id: 8187:LOC108876541
uniprot id: A0A4W6C904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

8187:LOC108892667
gene id: 8187:LOC108892667
uniprot id: A0A4W6DNH0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

8187:tfec
gene id: 8187:tfec
uniprot id: A0A4W6G2F8
uniprot id: A0A4W6G4I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8187:bnip3la
gene id: 8187:bnip3la
uniprot id: A0A4W6G698
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8187:sh2b3
gene id: 8187:sh2b3
uniprot id: A0A4W6CGF2
names: Similarity
messages: Belongs to the SH2B adapter family.

8187:dusp7
gene id: 8187:dusp7
uniprot id: A0A4W6DXQ1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8187:slc6a17
gene id: 8187:slc6a17
uniprot id: A0A4W6CJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8187:grinab
gene id: 8187:grinab
uniprot id: A0A4W6DLR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8187:m17
gene id: 8187:m17
uniprot id: A0A4W6CS21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

8187:mrpl14
gene id: 8187:mrpl14
uniprot id: A0A4W6BVY2
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

8187:il1rapl2
gene id: 8187:il1rapl2
uniprot id: A0A4W6FUJ4
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8187:LOC108888493
gene id: 8187:LOC108888493
uniprot id: A0A4W6F123
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

8187:l3mbtl1b
gene id: 8187:l3mbtl1b
uniprot id: A0A4W6CBD8
names: Subcellular Location Annotation
messages: Nucleus

8187:slc25a19
gene id: 8187:slc25a19
uniprot id: A0A4W6DWZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:ctnnbl1
gene id: 8187:ctnnbl1
uniprot id: A0A4W6CMR3
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108888239
gene id: 8187:LOC108888239
uniprot id: A0A4W6CH18
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108902461
gene id: 8187:LOC108902461
uniprot id: A0A4W6F3I8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:gins1
gene id: 8187:gins1
uniprot id: A0A4W6F272
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

8187:naa38
gene id: 8187:naa38
uniprot id: A0A4W6CP16
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

8187:ube2nb
gene id: 8187:ube2nb
uniprot id: A0A4W6CMA0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:snu13b
gene id: 8187:snu13b
uniprot id: A0A4W6CS63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

8187:nprl3
gene id: 8187:nprl3
uniprot id: A0A4W6BVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

8187:lg13h2orf68
gene id: 8187:lg13h2orf68
uniprot id: A0A4W6GA23
names: Similarity
messages: Belongs to the UPF0561 family.

8187:cry3a
gene id: 8187:cry3a
uniprot id: A0A4W6G254
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8187:gareml
gene id: 8187:gareml
uniprot id: A0A4W6DQP4
names: Similarity
messages: Belongs to the GAREM family.

8187:cdk4
gene id: 8187:cdk4
uniprot id: A0A4W6F4J9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108900755
gene id: 8187:LOC108900755
uniprot id: A0A4W6DU75
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8187:ggt5b
gene id: 8187:ggt5b
uniprot id: A0A4W6CKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8187:si:ch211-79m20.1
gene id: 8187:si:ch211-79m20.1
uniprot id: A0A4W6G859
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8187:kpna7
gene id: 8187:kpna7
uniprot id: A0A4W6D3H1
names: Similarity
messages: Belongs to the importin alpha family.

8187:plxna3
gene id: 8187:plxna3
uniprot id: A0A4W6FYD8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108895292
gene id: 8187:LOC108895292
uniprot id: A0A4W6FNQ3
names: Similarity
messages: Belongs to the GPSM family.

8187:mfap3l
gene id: 8187:mfap3l
uniprot id: A0A4W6D959
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108891957
gene id: 8187:LOC108891957
uniprot id: A0A4W6C9R4
names: Subcellular Location Annotation
messages: Cytoplasm

8187:sh3gl2a
gene id: 8187:sh3gl2a
uniprot id: A0A4W6CAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8187:dctn4
gene id: 8187:dctn4
uniprot id: A0A4W6CVD1
uniprot id: A0A4W6CW00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunit 4 family.
messages: cell cortex
messages: centrosome
messages: sarcomere
messages: stress fiber

8187:ncbp2
gene id: 8187:ncbp2
uniprot id: A0A4W6DP52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

8187:LOC108902460
gene id: 8187:LOC108902460
uniprot id: A0A4W6EZV1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:arcn1b
gene id: 8187:arcn1b
uniprot id: A0A4W6CMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

8187:nptx1l
gene id: 8187:nptx1l
uniprot id: A0A4W6BXF6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:nr2f5
gene id: 8187:nr2f5
uniprot id: A0A4W6BVU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:hexdc
gene id: 8187:hexdc
uniprot id: A0A4W6D705
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

8187:btk
gene id: 8187:btk
uniprot id: A0A4W6BTH1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8187:ssr3
gene id: 8187:ssr3
uniprot id: A0A4W6CNZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

8187:coq8b
gene id: 8187:coq8b
uniprot id: A0A4W6DN35
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8187:si:ch211-107o10.3
gene id: 8187:si:ch211-107o10.3
uniprot id: A0A4W6FL59
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:acat2
gene id: 8187:acat2
uniprot id: A0A4W6ELY7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8187:nme5
gene id: 8187:nme5
uniprot id: A0A4W6CH87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8187:gnmt
gene id: 8187:gnmt
uniprot id: A0A4W6DHL2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

8187:syt1b
gene id: 8187:syt1b
uniprot id: A0A4W6D7X8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

8187:mcts1
gene id: 8187:mcts1
uniprot id: A0A4W6FT57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

8187:LOC108872655
gene id: 8187:LOC108872655
uniprot id: A0A4W6D7A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

8187:pgm1
gene id: 8187:pgm1
uniprot id: A0A4W6DAV7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8187:tm6sf2a
gene id: 8187:tm6sf2a
uniprot id: A0A4W6E827
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

8187:sult4a1
gene id: 8187:sult4a1
uniprot id: A0A4W6ERM4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:atp6v0ca
gene id: 8187:atp6v0ca
uniprot id: A0A4W6BTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

8187:ddr1
gene id: 8187:ddr1
uniprot id: A0A4W6C6G0
uniprot id: A0A4W6CDR2
uniprot id: A0A4W6CDR6
names: Subcellular Location Annotation
messages: Membrane

8187:rock2a
gene id: 8187:rock2a
uniprot id: A0A4W6FBU3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

8187:rhbdl2
gene id: 8187:rhbdl2
uniprot id: A0A4W6C7C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

8187:tgfb5
gene id: 8187:tgfb5
uniprot id: A0A4W6EXZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

8187:LOC108888711
gene id: 8187:LOC108888711
uniprot id: A0A4W6EK94
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:mctp2a
gene id: 8187:mctp2a
uniprot id: A0A4W6CP67
names: Subcellular Location Annotation
messages: Membrane

8187:zgc:114130
gene id: 8187:zgc:114130
uniprot id: A0A4W6D2A2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8187:ankha
gene id: 8187:ankha
uniprot id: A0A4W6CRR2
uniprot id: A0A4W6CS70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

8187:LOC108875057
gene id: 8187:LOC108875057
uniprot id: A0A4W6EE03
names: Similarity
messages: Belongs to the yippee family.

8187:LOC108879749
gene id: 8187:LOC108879749
uniprot id: A0A4W6FRP4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:dkk2
gene id: 8187:dkk2
uniprot id: A0A4W6CG21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

8187:LOC108884433
gene id: 8187:LOC108884433
uniprot id: A0A4W6ER29
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8187:qki2
gene id: 8187:qki2
uniprot id: A0A4W6DYC5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:mtnr1c
gene id: 8187:mtnr1c
uniprot id: A0A4W6DFA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8187:LOC108885165
gene id: 8187:LOC108885165
uniprot id: A0A4W6G9N8
names: Subcellular Location Annotation
messages: Nucleus

8187:sdhc
gene id: 8187:sdhc
uniprot id: A0A4W6BPE7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

8187:cavin1a
gene id: 8187:cavin1a
uniprot id: A0A4W6CR36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8187:LOC108875822
gene id: 8187:LOC108875822
uniprot id: A0A4W6FUV0
names: Similarity
messages: Belongs to the heme oxygenase family.

8187:mpv17
gene id: 8187:mpv17
uniprot id: A0A4W6DFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8187:LOC108876975
gene id: 8187:LOC108876975
uniprot id: A0A4W6FUS2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:pou3f3b
gene id: 8187:pou3f3b
uniprot id: A0A4W6D846
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8187:polr3b
gene id: 8187:polr3b
uniprot id: A0A4W6E8M6
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

8187:leprotl1
gene id: 8187:leprotl1
uniprot id: A0A4W6BPI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

8187:zmp:0000001048
gene id: 8187:zmp:0000001048
uniprot id: A0A4W6DVS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:peds1
gene id: 8187:peds1
uniprot id: A0A4W6ECC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

8187:arl3l1
gene id: 8187:arl3l1
uniprot id: A0A4W6C4C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8187:si:ch211-157c3.4
gene id: 8187:si:ch211-157c3.4
uniprot id: A0A4W6CA74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

8187:tgfb1a
gene id: 8187:tgfb1a
uniprot id: A0A4W6CSX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

8187:rpl10
gene id: 8187:rpl10
uniprot id: A0A4W6ETL6
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

8187:LOC108879606
gene id: 8187:LOC108879606
uniprot id: A0A4W6FAV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8187:lonp1
gene id: 8187:lonp1
uniprot id: A0A4W6BXF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

8187:alkal2b
gene id: 8187:alkal2b
uniprot id: A0A4W6CP88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

8187:polm
gene id: 8187:polm
uniprot id: A0A4W6EUZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).
messages: Nucleus

8187:snapin
gene id: 8187:snapin
uniprot id: A0A4W6CH54
names: Similarity
messages: Belongs to the SNAPIN family.

8187:LOC108890595
gene id: 8187:LOC108890595
uniprot id: A0A4W6FR25
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8187:malt3
gene id: 8187:malt3
uniprot id: A0A4W6CGJ6
names: Subcellular Location Annotation
messages: Membrane

8187:zgc:65997
gene id: 8187:zgc:65997
uniprot id: A0A4W6EZ33
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:pigh
gene id: 8187:pigh
uniprot id: A0A4W6ERZ8
names: Similarity
messages: Belongs to the PIGH family.

8187:aprt
gene id: 8187:aprt
uniprot id: A0A4W6BML3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

8187:pmvk
gene id: 8187:pmvk
uniprot id: A0A4W6DEE6
names: Subcellular Location Annotation
messages: cytosol

8187:LOC108875342
gene id: 8187:LOC108875342
uniprot id: A0A4W6CE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8187:LOC108899083
gene id: 8187:LOC108899083
uniprot id: A0A4W6DWD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

8187:map2k1
gene id: 8187:map2k1
uniprot id: A0A4W6DMV2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:kirrel1a
gene id: 8187:kirrel1a
uniprot id: A0A4W6D6Y9
names: Subcellular Location Annotation
messages: Membrane

8187:lcat
gene id: 8187:lcat
uniprot id: A0A4W6EEK3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

8187:mogat2
gene id: 8187:mogat2
uniprot id: A0A4W6EAN1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:icmt
gene id: 8187:icmt
uniprot id: A0A4W6E7B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:cse1l
gene id: 8187:cse1l
uniprot id: A0A4W6G0B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

8187:pvalb7
gene id: 8187:pvalb7
uniprot id: A0A4W6G943
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8187:tgfb2
gene id: 8187:tgfb2
uniprot id: A0A4W6C0L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

8187:ftsj1
gene id: 8187:ftsj1
uniprot id: A0A4W6BRQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

8187:LOC108874378
gene id: 8187:LOC108874378
uniprot id: A0A4W6BXW3
names: Similarity
messages: Belongs to the Bcl-2 family.

8187:bckdha
gene id: 8187:bckdha
uniprot id: A0A4W6CFW6
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

8187:rbbp5
gene id: 8187:rbbp5
uniprot id: A0A4W6C6R7
names: Subcellular Location Annotation
messages: Nucleus

8187:dnmt3bb.1
gene id: 8187:dnmt3bb.1
uniprot id: A0A4W6EZJ4
uniprot id: A0A4W6EZK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

8187:actn1
gene id: 8187:actn1
uniprot id: A0A4W6FFC7
uniprot id: A0A4W6FI22
names: Similarity
messages: Belongs to the alpha-actinin family.

8187:tmem54b
gene id: 8187:tmem54b
uniprot id: A0A4W6BUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8187:scamp5a
gene id: 8187:scamp5a
uniprot id: A0A4W6CYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8187:mturn
gene id: 8187:mturn
uniprot id: A0A4W6FQV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

8187:pole
gene id: 8187:pole
uniprot id: A0A4W6GAE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

8187:foxo1a
gene id: 8187:foxo1a
uniprot id: A0A4W6C8X2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:lbh
gene id: 8187:lbh
uniprot id: A0A4W6EG99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus

8187:timm23a
gene id: 8187:timm23a
uniprot id: A0A4W6DVU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

8187:anxa6
gene id: 8187:anxa6
uniprot id: A0A4W6D1V6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

8187:opn7a
gene id: 8187:opn7a
uniprot id: A0A4W6D675
names: Subcellular Location Annotation
messages: Membrane

8187:gipc2
gene id: 8187:gipc2
uniprot id: A0A4W6FUR9
names: Similarity
messages: Belongs to the GIPC family.

8187:hoxb9a
gene id: 8187:hoxb9a
uniprot id: A0A4W6CB16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8187:fgf8a
gene id: 8187:fgf8a
uniprot id: A0A4W6DPA2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:gadd45ab
gene id: 8187:gadd45ab
uniprot id: A0A4W6CWK6
names: Similarity
messages: Belongs to the GADD45 family.

8187:LOC108885764
gene id: 8187:LOC108885764
uniprot id: A0A4W6C3B2
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

8187:vps11
gene id: 8187:vps11
uniprot id: A0A4W6DBV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

8187:cks1b
gene id: 8187:cks1b
uniprot id: A0A4W6FDS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

8187:ppap2d
gene id: 8187:ppap2d
uniprot id: A0A4W6FSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8187:nck2a
gene id: 8187:nck2a
uniprot id: A0A4W6CSE9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

8187:LOC108891105
gene id: 8187:LOC108891105
uniprot id: A0A4W6D395
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8187:galnt2
gene id: 8187:galnt2
uniprot id: A0A4W6G292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108876102
gene id: 8187:LOC108876102
uniprot id: A0A4W6DW09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

8187:stk35
gene id: 8187:stk35
uniprot id: A0A4W6CPX2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108872545
gene id: 8187:LOC108872545
uniprot id: A0A4W6BL15
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8187:prpf19
gene id: 8187:prpf19
uniprot id: A0A4W6BZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

8187:LOC108895900
gene id: 8187:LOC108895900
uniprot id: A0A4W6BTQ0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8187:LOC108877485
gene id: 8187:LOC108877485
uniprot id: A0A4W6C5Q9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:taf11
gene id: 8187:taf11
uniprot id: A0A4W6DDP2
names: Similarity
messages: Belongs to the TAF11 family.

8187:si:dkey-71l1.1
gene id: 8187:si:dkey-71l1.1
uniprot id: A0A4W6D5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8187:spice1
gene id: 8187:spice1
uniprot id: A0A4W6DKX3
names: Subcellular Location Annotation
messages: centriole
messages: spindle

8187:ell2
gene id: 8187:ell2
uniprot id: A0A4W6CSR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8187:gstt1a
gene id: 8187:gstt1a
uniprot id: A0A4W6CRC8
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

8187:LOC108900594
gene id: 8187:LOC108900594
uniprot id: A0A4W6FN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:gch1
gene id: 8187:gch1
uniprot id: A0A4W6EKF9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

8187:LOC108887672
gene id: 8187:LOC108887672
uniprot id: A0A4W6D1L1
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

8187:rab32a
gene id: 8187:rab32a
uniprot id: A0A4W6CW46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8187:wu:fb13g09
gene id: 8187:wu:fb13g09
uniprot id: A0A4W6BNA3
names: Subcellular Location Annotation
messages: Membrane

8187:vwc2l
gene id: 8187:vwc2l
uniprot id: A0A4W6EXD6
names: Subcellular Location Annotation
messages: Synapse

8187:plp1a
gene id: 8187:plp1a
uniprot id: A0A4W6DSL1
uniprot id: A0A4W6DUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8187:LOC108885908
gene id: 8187:LOC108885908
uniprot id: A0A4W6FQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

8187:smim15
gene id: 8187:smim15
uniprot id: A0A4W6BX32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

8187:pipox
gene id: 8187:pipox
uniprot id: A0A4W6CBL6
names: Similarity
messages: Belongs to the MSOX/MTOX family.

8187:dram1
gene id: 8187:dram1
uniprot id: A0A4W6FEX5
names: Subcellular Location Annotation
messages: Membrane

8187:tmod2
gene id: 8187:tmod2
uniprot id: A0A4W6CGQ0
names: Subcellular Location Annotation
messages: cytoskeleton

8187:pard6gb
gene id: 8187:pard6gb
uniprot id: A0A4W6DYT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

8187:fam167b
gene id: 8187:fam167b
uniprot id: A0A4W6DL12
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

8187:gapdhs
gene id: 8187:gapdhs
uniprot id: A0A4W6EDU9
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

8187:slc27a6
gene id: 8187:slc27a6
uniprot id: A0A4W6G929
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8187:p2rx1
gene id: 8187:p2rx1
uniprot id: A0A4W6EIC1
uniprot id: A0A4W6EKH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8187:pex10
gene id: 8187:pex10
uniprot id: A0A4W6CXJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

8187:alg10
gene id: 8187:alg10
uniprot id: A0A4W6E3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Membrane

8187:selenbp1
gene id: 8187:selenbp1
uniprot id: A0A4W6DM39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

8187:bmp4
gene id: 8187:bmp4
uniprot id: A0A4W6EGN7
names: Similarity
messages: Belongs to the TGF-beta family.

8187:ndufa5
gene id: 8187:ndufa5
uniprot id: A0A4W6EW45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8187:washc3
gene id: 8187:washc3
uniprot id: A0A4W6FGU3
names: Similarity
messages: Belongs to the CCDC53 family.

8187:b4galt1l
gene id: 8187:b4galt1l
uniprot id: A0A4W6C6F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8187:rplp1
gene id: 8187:rplp1
uniprot id: A0A4W6DRG5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

8187:cep43
gene id: 8187:cep43
uniprot id: A0A4W6FW23
uniprot id: A0A4W6FW33
uniprot id: A0A4W6FW43
uniprot id: A0A4W6FWS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

8187:eftud2
gene id: 8187:eftud2
uniprot id: A0A4W6FJL8
names: Subcellular Location Annotation
messages: Nucleus

8187:hacd1
gene id: 8187:hacd1
uniprot id: A0A4W6CGW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:mknk1
gene id: 8187:mknk1
uniprot id: A0A4W6DIF5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108885100
gene id: 8187:LOC108885100
uniprot id: A0A4W6BJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8187:grk1b
gene id: 8187:grk1b
uniprot id: A0A4W6BMI9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8187:gfm2
gene id: 8187:gfm2
uniprot id: A0A4W6F3C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

8187:LOC108893571
gene id: 8187:LOC108893571
uniprot id: A0A4W6FLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

8187:LOC108891357
gene id: 8187:LOC108891357
uniprot id: A0A4W6FJY6
names: Similarity
messages: Belongs to the peptidase M67C family.

8187:camk2n1
gene id: 8187:camk2n1
uniprot id: A0A4W6CAB1
names: Similarity
messages: Belongs to the CAMK2N family.

8187:tmem208
gene id: 8187:tmem208
uniprot id: A0A4W6BUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

8187:ago1
gene id: 8187:ago1
uniprot id: A0A4W6C5H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

8187:pcnx1
gene id: 8187:pcnx1
uniprot id: A0A4W6FD27
uniprot id: A0A4W6FFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

8187:LOC108891107
gene id: 8187:LOC108891107
uniprot id: A0A4W6DSW2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:riok2
gene id: 8187:riok2
uniprot id: A0A4W6GAN2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

8187:unc119a
gene id: 8187:unc119a
uniprot id: A0A4W6DNW9
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8187:polr2a
gene id: 8187:polr2a
uniprot id: A0A4W6CUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

8187:nr5a2
gene id: 8187:nr5a2
uniprot id: A0A4W6D7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

8187:zgc:113054
gene id: 8187:zgc:113054
uniprot id: A0A4W6FYJ9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

8187:ifrd1
gene id: 8187:ifrd1
uniprot id: A0A4W6G4L0
names: Similarity
messages: Belongs to the IFRD family.

8187:LOC108893617
gene id: 8187:LOC108893617
uniprot id: A0A4W6FIR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:pnpo
gene id: 8187:pnpo
uniprot id: A0A4W6E094
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

8187:crkl
gene id: 8187:crkl
uniprot id: A0A4W6DH10
names: Similarity
messages: Belongs to the CRK family.

8187:dok1b
gene id: 8187:dok1b
uniprot id: A0A4W6ELB9
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

8187:sar1ab
gene id: 8187:sar1ab
uniprot id: A0A4W6D580
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

8187:lyrm5a
gene id: 8187:lyrm5a
uniprot id: A0A4W6E0W6
names: Similarity
messages: Belongs to the complex I LYR family.

8187:tmem144b
gene id: 8187:tmem144b
uniprot id: A0A4W6FEE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

8187:map7a
gene id: 8187:map7a
uniprot id: A0A4W6EUF0
uniprot id: A0A4W6EVD5
names: Similarity
messages: Belongs to the MAP7 family.

8187:fmnl3
gene id: 8187:fmnl3
uniprot id: A0A4W6FFG5
uniprot id: A0A4W6FG82
uniprot id: A0A4W6FH97
names: Similarity
messages: Belongs to the formin homology family.

8187:LOC108897929
gene id: 8187:LOC108897929
uniprot id: A0A4W6FAJ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

8187:ybey
gene id: 8187:ybey
uniprot id: A0A4W6FDF5
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

8187:tapt1b
gene id: 8187:tapt1b
uniprot id: A0A4W6EI90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

8187:LOC108872456
gene id: 8187:LOC108872456
uniprot id: A0A4W6DHC7
names: Similarity
messages: Belongs to the HARBI1 family.

8187:lhx6a
gene id: 8187:lhx6a
uniprot id: A0A4W6C6Y0
names: Subcellular Location Annotation
messages: Nucleus

8187:glmp
gene id: 8187:glmp
uniprot id: A0A4W6DXW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLMP family.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

8187:LOC108885534
gene id: 8187:LOC108885534
uniprot id: A0A4W6EK56
uniprot id: A0A4W6EQJ2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8187:pold3
gene id: 8187:pold3
uniprot id: A0A4W6C828
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108887527
gene id: 8187:LOC108887527
uniprot id: A0A4W6FLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

8187:crybb2
gene id: 8187:crybb2
uniprot id: A0A4W6F2W6
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:acer3
gene id: 8187:acer3
uniprot id: A0A4W6E0D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:rpl23
gene id: 8187:rpl23
uniprot id: A0A4W6DVB2
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

8187:LOC108898010
gene id: 8187:LOC108898010
uniprot id: A0A4W6DYS7
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8187:ccnd3
gene id: 8187:ccnd3
uniprot id: A0A4W6ENP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:LOC108887884
gene id: 8187:LOC108887884
uniprot id: A0A4W6BUX0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8187:LOC108902936
gene id: 8187:LOC108902936
uniprot id: A0A4W6BYY2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8187:LOC108901713
gene id: 8187:LOC108901713
uniprot id: A0A4W6C1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: podosome

8187:gosr2
gene id: 8187:gosr2
uniprot id: A0A4W6CQ38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

8187:si:dkey-76k16.6
gene id: 8187:si:dkey-76k16.6
uniprot id: A0A4W6BVZ0
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

8187:slc16a5a
gene id: 8187:slc16a5a
uniprot id: A0A4W6E0S2
names: Subcellular Location Annotation
messages: Membrane

8187:eif3i
gene id: 8187:eif3i
uniprot id: A0A4W6CDC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8187:cpt2
gene id: 8187:cpt2
uniprot id: A0A4W6CU47
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8187:LOC108895681
gene id: 8187:LOC108895681
uniprot id: A0A4W6CYQ5
names: Subcellular Location Annotation
messages: Nucleus

8187:ghrhrb
gene id: 8187:ghrhrb
uniprot id: A0A4W6F7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8187:LOC108897711
gene id: 8187:LOC108897711
uniprot id: A0A4W6G0M4
names: Subcellular Location Annotation
messages: Membrane

8187:tsen34
gene id: 8187:tsen34
uniprot id: A0A4W6BQR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

8187:LOC108879544
gene id: 8187:LOC108879544
uniprot id: A0A4W6F9W7
names: Subcellular Location Annotation
messages: extracellular space

8187:LOC108896919
gene id: 8187:LOC108896919
uniprot id: A0A4W6DMG1
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8187:copz1
gene id: 8187:copz1
uniprot id: A0A4W6FLV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

8187:nova2
gene id: 8187:nova2
uniprot id: A0A4W6CYT7
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

8187:atp6ap1a
gene id: 8187:atp6ap1a
uniprot id: A0A4W6ET10
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

8187:padi2
gene id: 8187:padi2
uniprot id: A0A4W6D6M3
uniprot id: A0A4W6D6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

8187:slc25a29
gene id: 8187:slc25a29
uniprot id: A0A4W6ET03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:lacc1
gene id: 8187:lacc1
uniprot id: A0A4W6EUR8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

8187:fshb
gene id: 8187:fshb
uniprot id: A0A4W6EQD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8187:nfixa
gene id: 8187:nfixa
uniprot id: A0A4W6FTV0
uniprot id: A0A4W6FUA4
uniprot id: A0A4W6FUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

8187:rbp7b
gene id: 8187:rbp7b
uniprot id: A0A4W6CUG8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8187:unm hu7910
gene id: 8187:unm_hu7910
uniprot id: A0A4W6FRK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

8187:oxa1l
gene id: 8187:oxa1l
uniprot id: A0A4W6CNG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

8187:agps
gene id: 8187:agps
uniprot id: A0A4W6EEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

8187:tmem70
gene id: 8187:tmem70
uniprot id: A0A4W6BMZ7
names: Similarity
messages: Belongs to the TMEM70 family.

8187:hoxc4a
gene id: 8187:hoxc4a
uniprot id: A0A4W6FMD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8187:prf1.5
gene id: 8187:prf1.5
uniprot id: A0A4W6BMN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8187:pdca
gene id: 8187:pdca
uniprot id: A0A4W6E5U9
names: Similarity
messages: Belongs to the phosducin family.

8187:LOC108902324
gene id: 8187:LOC108902324
uniprot id: A0A4W6EM75
names: Subcellular Location Annotation
messages: Cytoplasm

8187:anxa3a
gene id: 8187:anxa3a
uniprot id: A0A4W6CP85
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8187:lrrc51
gene id: 8187:lrrc51
uniprot id: A0A4W6F4H6
names: Subcellular Location Annotation
messages: Cytoplasm

8187:gpr17
gene id: 8187:gpr17
uniprot id: A0A4W6DID2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:wfikkn2a
gene id: 8187:wfikkn2a
uniprot id: A0A4W6E1W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane
messages: Secreted

8187:il13ra2
gene id: 8187:il13ra2
uniprot id: A0A4W6CKU1
names: Subcellular Location Annotation
messages: Membrane

8187:coq4
gene id: 8187:coq4
uniprot id: A0A4W6CVU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

8187:LOC108901990
gene id: 8187:LOC108901990
uniprot id: A0A4W6DMB1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:aqp10a
gene id: 8187:aqp10a
uniprot id: A0A4W6FVU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8187:natd1
gene id: 8187:natd1
uniprot id: A0A4W6BKE1
names: Similarity
messages: Belongs to the NATD1 family.

8187:LOC108880451
gene id: 8187:LOC108880451
uniprot id: A0A4W6FDG7
names: Similarity
messages: Belongs to the peptidase C14A family.

8187:phb
gene id: 8187:phb
uniprot id: A0A4W6FH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

8187:ptprfa
gene id: 8187:ptprfa
uniprot id: A0A4W6C2N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
messages: Membrane

8187:slc39a8
gene id: 8187:slc39a8
uniprot id: A0A4W6DLI9
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108902943
gene id: 8187:LOC108902943
uniprot id: A0A4W6C3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8187:atp6ap2
gene id: 8187:atp6ap2
uniprot id: A0A4W6D9M0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

8187:pter
gene id: 8187:pter
uniprot id: A0A4W6BNY8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:chst7
gene id: 8187:chst7
uniprot id: A0A4W6DW15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8187:LOC108882159
gene id: 8187:LOC108882159
uniprot id: A0A4W6DP23
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108893957
gene id: 8187:LOC108893957
uniprot id: A0A4W6F4N3
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

8187:gsg1l
gene id: 8187:gsg1l
uniprot id: A0A4W6E0R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8187:kcna4
gene id: 8187:kcna4
uniprot id: A0A4W6ER83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

8187:golm1
gene id: 8187:golm1
uniprot id: A0A4W6GBQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

8187:dedd1
gene id: 8187:dedd1
uniprot id: A0A4W6BIN9
uniprot id: A0A4W6BMA3
names: Subcellular Location Annotation
messages: nucleolus

8187:cartl
gene id: 8187:cartl
uniprot id: A0A4W6C2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8187:nkx2.1
gene id: 8187:nkx2.1
uniprot id: A0A4W6C0R9
names: Subcellular Location Annotation
messages: Nucleus

8187:skor1a
gene id: 8187:skor1a
uniprot id: A0A4W6BU93
names: Similarity
messages: Belongs to the SKI family.

8187:srm
gene id: 8187:srm
uniprot id: A0A4W6CF23
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

8187:tfap2d
gene id: 8187:tfap2d
uniprot id: A0A4W6DP21
names: Similarity
messages: Belongs to the AP-2 family.

8187:si:dkey-222f2.1
gene id: 8187:si:dkey-222f2.1
uniprot id: A0A4W6DCJ9
names: Similarity
messages: Belongs to the intermediate filament family.

8187:pfdn5
gene id: 8187:pfdn5
uniprot id: A0A4W6EJ52
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

8187:bdkrb1
gene id: 8187:bdkrb1
uniprot id: A0A4W6EQF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.

8187:LOC108877942
gene id: 8187:LOC108877942
uniprot id: A0A4W6EL81
names: Subcellular Location Annotation
messages: Membrane

8187:lpl
gene id: 8187:lpl
uniprot id: A0A4W6G3L3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

8187:gnb1b
gene id: 8187:gnb1b
uniprot id: A0A4W6CIZ2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8187:psmd9
gene id: 8187:psmd9
uniprot id: A0A4W6GA78
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

8187:lpar3
gene id: 8187:lpar3
uniprot id: A0A4W6FBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:rxrbb
gene id: 8187:rxrbb
uniprot id: A0A4W6D2U9
uniprot id: A0A4W6D2Y2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

8187:hrh1
gene id: 8187:hrh1
uniprot id: A0A4W6EZ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8187:LOC108877928
gene id: 8187:LOC108877928
uniprot id: A0A4W6ES35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:LOC108889992
gene id: 8187:LOC108889992
uniprot id: A0A4W6CK97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8187:stxbp2
gene id: 8187:stxbp2
uniprot id: A0A4W6FQ33
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8187:ccr7
gene id: 8187:ccr7
uniprot id: A0A4W6D6P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8187:ppp1cc
gene id: 8187:ppp1cc
uniprot id: A0A4W6G6V2
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

8187:LOC108901063
gene id: 8187:LOC108901063
uniprot id: A0A4W6FPS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8187:clcn5b
gene id: 8187:clcn5b
uniprot id: A0A4W6FNM4
uniprot id: A0A4W6FPF8
uniprot id: A0A4W6FQ96
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:dennd6b
gene id: 8187:dennd6b
uniprot id: A0A4W6DG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

8187:LOC108881650
gene id: 8187:LOC108881650
uniprot id: A0A4W6CSC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8187:LOC108884223
gene id: 8187:LOC108884223
uniprot id: A0A4W6FFS2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8187:trim35-13
gene id: 8187:trim35-13
uniprot id: A0A4W6FSG2
names: Subcellular Location Annotation
messages: Cytoplasm

8187:pes
gene id: 8187:pes
uniprot id: A0A4W6GB99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

8187:leap2
gene id: 8187:leap2
uniprot id: A0A4W6FPZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

8187:tnfsf12
gene id: 8187:tnfsf12
uniprot id: A0A4W6CQS0
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8187:LOC108883045
gene id: 8187:LOC108883045
uniprot id: A0A4W6CPP5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8187:LOC108902913
gene id: 8187:LOC108902913
uniprot id: A0A4W6CDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

8187:LOC108877701
gene id: 8187:LOC108877701
uniprot id: A0A4W6EV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8187:slc39a10
gene id: 8187:slc39a10
uniprot id: A0A4W6CXB2
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108895619
gene id: 8187:LOC108895619
uniprot id: A0A4W6D0A0
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

8187:tmem120b
gene id: 8187:tmem120b
uniprot id: A0A4W6CPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

8187:gatb
gene id: 8187:gatb
uniprot id: A0A4W6EQA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8187:st6galnac6
gene id: 8187:st6galnac6
uniprot id: A0A4W6BTT0
uniprot id: A0A4W6BWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8187:capzb
gene id: 8187:capzb
uniprot id: A0A4W6EQ87
uniprot id: A0A4W6ESB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

8187:ddit4
gene id: 8187:ddit4
uniprot id: A0A4W6F0M2
names: Similarity
messages: Belongs to the DDIT4 family.

8187:LOC108876026
gene id: 8187:LOC108876026
uniprot id: A0A4W6E013
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8187:cilp
gene id: 8187:cilp
uniprot id: A0A4W6F0R8
names: Subcellular Location Annotation
messages: Membrane
messages: extracellular matrix

8187:atg2b
gene id: 8187:atg2b
uniprot id: A0A4W6F0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

8187:aplp1
gene id: 8187:aplp1
uniprot id: A0A4W6CXX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108872663
gene id: 8187:LOC108872663
uniprot id: A0A4W6EI56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:slc16a10
gene id: 8187:slc16a10
uniprot id: A0A4W6BSX1
names: Subcellular Location Annotation
messages: Membrane

8187:tctn2
gene id: 8187:tctn2
uniprot id: A0A4W6GB69
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

8187:LOC108879593
gene id: 8187:LOC108879593
uniprot id: A0A4W6F6M3
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8187:LOC108883878
gene id: 8187:LOC108883878
uniprot id: A0A4W6CAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:slc25a20
gene id: 8187:slc25a20
uniprot id: A0A4W6ES52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:tysnd1
gene id: 8187:tysnd1
uniprot id: A0A4W6D5M8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

8187:mrpl18
gene id: 8187:mrpl18
uniprot id: A0A4W6C4M4
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

8187:flvcr2a
gene id: 8187:flvcr2a
uniprot id: A0A4W6EXJ8
uniprot id: A0A4W6EXM3
uniprot id: A0A4W6EZH7
names: Subcellular Location Annotation
messages: Membrane

8187:arrdc1a
gene id: 8187:arrdc1a
uniprot id: A0A4W6G592
names: Similarity
messages: Belongs to the arrestin family.

8187:LOC108879399
gene id: 8187:LOC108879399
uniprot id: A0A4W6G0B5
uniprot id: A0A4W6G0D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

8187:LOC108892481
gene id: 8187:LOC108892481
uniprot id: A0A4W6FS92
names: Similarity
messages: Belongs to the peptidase S1C family.

8187:LOC108889304
gene id: 8187:LOC108889304
uniprot id: A0A4W6FVE1
uniprot id: A0A4W6FWZ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:amt
gene id: 8187:amt
uniprot id: A0A4W6G8J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8187:nadkb
gene id: 8187:nadkb
uniprot id: A0A4W6E752
names: Similarity
messages: Belongs to the NAD kinase family.

8187:camk1db
gene id: 8187:camk1db
uniprot id: A0A4W6F4T0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:abraxas2
gene id: 8187:abraxas2
uniprot id: A0A4W6DMZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abro1 subfamily.
messages: Nucleus
messages: spindle pole

8187:cilp2
gene id: 8187:cilp2
uniprot id: A0A4W6DB52
names: Subcellular Location Annotation
messages: Membrane
messages: extracellular matrix

8187:wars1
gene id: 8187:wars1
uniprot id: A0A4W6F325
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8187:steap2
gene id: 8187:steap2
uniprot id: A0A4W6ENS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8187:kirrel3l
gene id: 8187:kirrel3l
uniprot id: A0A4W6CZM9
names: Subcellular Location Annotation
messages: Membrane

8187:lbr
gene id: 8187:lbr
uniprot id: A0A4W6DPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

8187:cpeb2
gene id: 8187:cpeb2
uniprot id: A0A4W6E155
uniprot id: A0A4W6E3Z5
uniprot id: A0A4W6E402
names: Similarity
messages: Belongs to the RRM CPEB family.

8187:htra4
gene id: 8187:htra4
uniprot id: A0A4W6G4N2
names: Similarity
messages: Belongs to the peptidase S1C family.

8187:LOC108899804
gene id: 8187:LOC108899804
uniprot id: A0A4W6DNF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:rpl14
gene id: 8187:rpl14
uniprot id: A0A4W6FNZ5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

8187:tspan17
gene id: 8187:tspan17
uniprot id: A0A4W6CUX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:fmnl1a
gene id: 8187:fmnl1a
uniprot id: A0A4W6CQM5
names: Similarity
messages: Belongs to the formin homology family.

8187:LOC108897045
gene id: 8187:LOC108897045
uniprot id: A0A4W6E9P0
names: Similarity
messages: Belongs to the peptidase C19 family.

8187:LOC108887865
gene id: 8187:LOC108887865
uniprot id: A0A4W6BN67
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8187:mtfp1
gene id: 8187:mtfp1
uniprot id: A0A4W6E8R0
names: Similarity
messages: Belongs to the MTFP1 family.

8187:tyrobp
gene id: 8187:tyrobp
uniprot id: A0A4W6D0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TYROBP family.
messages: Cell membrane
messages: Membrane

8187:tph2
gene id: 8187:tph2
uniprot id: A0A4W6C6H8
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8187:ptger2b
gene id: 8187:ptger2b
uniprot id: A0A4W6DJH2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:LOC108882716
gene id: 8187:LOC108882716
uniprot id: A0A4W6BR78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

8187:fgf13a
gene id: 8187:fgf13a
uniprot id: A0A4W6ECX5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:rassf3
gene id: 8187:rassf3
uniprot id: A0A4W6D8T9
names: Subcellular Location Annotation
messages: cytoskeleton

8187:slc25a14
gene id: 8187:slc25a14
uniprot id: A0A4W6FKD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:pim2
gene id: 8187:pim2
uniprot id: A0A4W6FYM8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8187:cers3b
gene id: 8187:cers3b
uniprot id: A0A4W6D6P5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8187:prkacbb
gene id: 8187:prkacbb
uniprot id: A0A4W6D433
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

8187:pdcb
gene id: 8187:pdcb
uniprot id: A0A4W6CYC9
names: Similarity
messages: Belongs to the phosducin family.

8187:sugt1
gene id: 8187:sugt1
uniprot id: A0A4W6CAK0
names: Similarity
messages: Belongs to the SGT1 family.

8187:synm
gene id: 8187:synm
uniprot id: A0A4W6CP64
names: Similarity
messages: Belongs to the intermediate filament family.

8187:kif15
gene id: 8187:kif15
uniprot id: A0A4W6FKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.
messages: spindle

8187:btc
gene id: 8187:btc
uniprot id: A0A4W6C9E7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:atp5mc3a
gene id: 8187:atp5mc3a
uniprot id: A0A4W6EB80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

8187:tmem86a
gene id: 8187:tmem86a
uniprot id: A0A4W6EIF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

8187:LOC108883649
gene id: 8187:LOC108883649
uniprot id: A0A4W6F3N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:dpm3
gene id: 8187:dpm3
uniprot id: A0A4W6FDR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

8187:psen2
gene id: 8187:psen2
uniprot id: A0A4W6E5H8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

8187:aldh18a1
gene id: 8187:aldh18a1
uniprot id: A0A4W6BSG6
uniprot id: A0A4W6BVF6
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

8187:LOC108876303
gene id: 8187:LOC108876303
uniprot id: A0A4W6EQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

8187:slc35f1
gene id: 8187:slc35f1
uniprot id: A0A4W6DQ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

8187:LOC108891880
gene id: 8187:LOC108891880
uniprot id: A0A4W6FJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:msi2b
gene id: 8187:msi2b
uniprot id: A0A4W6CLZ7
uniprot id: A0A4W6CM14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

8187:sf3a1
gene id: 8187:sf3a1
uniprot id: A0A4W6FQD9
names: Subcellular Location Annotation
messages: Nucleus

8187:slc18a2
gene id: 8187:slc18a2
uniprot id: A0A4W6EBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

8187:LOC108894332
gene id: 8187:LOC108894332
uniprot id: A0A4W6CWY7
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8187:prpf38b
gene id: 8187:prpf38b
uniprot id: A0A4W6EAB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

8187:si:ch211-284o19.8
gene id: 8187:si:ch211-284o19.8
uniprot id: A0A4W6BRR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8187:LOC108876447
gene id: 8187:LOC108876447
uniprot id: A0A4W6CJ78
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

8187:limk2
gene id: 8187:limk2
uniprot id: A0A4W6GBG1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8187:si:dkeyp-14d3.1
gene id: 8187:si:dkeyp-14d3.1
uniprot id: A0A4W6FMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8187:LOC108892057
gene id: 8187:LOC108892057
uniprot id: A0A4W6E639
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

8187:anxa5a
gene id: 8187:anxa5a
uniprot id: A0A4W6G107
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8187:b4galt7
gene id: 8187:b4galt7
uniprot id: A0A4W6G565
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8187:cenpl
gene id: 8187:cenpl
uniprot id: A0A4W6FPA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

8187:tmem178a
gene id: 8187:tmem178a
uniprot id: A0A4W6DJD1
names: Similarity
messages: Belongs to the TMEM178 family.

8187:zgc:111976
gene id: 8187:zgc:111976
uniprot id: A0A4W6DY66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8187:arl8bb
gene id: 8187:arl8bb
uniprot id: A0A4W6EL86
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8187:LOC108895310
gene id: 8187:LOC108895310
uniprot id: A0A4W6CVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

8187:LOC108881954
gene id: 8187:LOC108881954
uniprot id: A0A4W6ETA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:ccdc167
gene id: 8187:ccdc167
uniprot id: A0A4W6DDH7
names: Subcellular Location Annotation
messages: Membrane

8187:fam49al
gene id: 8187:fam49al
uniprot id: A0A4W6FPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

8187:LOC108883922
gene id: 8187:LOC108883922
uniprot id: A0A4W6CGB8
names: Subcellular Location Annotation
messages: Membrane

8187:prkar2aa
gene id: 8187:prkar2aa
uniprot id: A0A4W6G8K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8187:snupn
gene id: 8187:snupn
uniprot id: A0A4W6CNV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

8187:trpt1
gene id: 8187:trpt1
uniprot id: A0A4W6EWX0
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

8187:smoc2
gene id: 8187:smoc2
uniprot id: A0A4W6FCI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:tnfaip6
gene id: 8187:tnfaip6
uniprot id: A0A4W6F1M8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:irf1b
gene id: 8187:irf1b
uniprot id: A0A4W6E965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

8187:cav2
gene id: 8187:cav2
uniprot id: A0A4W6BZU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8187:f5
gene id: 8187:f5
uniprot id: A0A4W6ED98
names: Similarity
messages: Belongs to the multicopper oxidase family.

8187:tmem176
gene id: 8187:tmem176
uniprot id: A0A4W6E0B9
names: Similarity
messages: Belongs to the MS4A family.

8187:nrn1lb
gene id: 8187:nrn1lb
uniprot id: A0A4W6C0W0
names: Similarity
messages: Belongs to the neuritin family.

8187:prdm4
gene id: 8187:prdm4
uniprot id: A0A4W6FLQ4
names: Subcellular Location Annotation
messages: Nucleus

8187:arhgef11
gene id: 8187:arhgef11
uniprot id: A0A4W6EDE5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

8187:rln3a
gene id: 8187:rln3a
uniprot id: A0A4W6DWI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8187:stc2a
gene id: 8187:stc2a
uniprot id: A0A4W6CSZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

8187:LOC108874022
gene id: 8187:LOC108874022
uniprot id: A0A4W6BZH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

8187:ormdl1
gene id: 8187:ormdl1
uniprot id: A0A4W6BJG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8187:nfe2l2a
gene id: 8187:nfe2l2a
uniprot id: A0A4W6E7N0
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8187:esyt2b
gene id: 8187:esyt2b
uniprot id: A0A4W6FJ22
uniprot id: A0A4W6FJ41
uniprot id: A0A4W6FJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108901365
gene id: 8187:LOC108901365
uniprot id: A0A4W6D258
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:c1s.2
gene id: 8187:c1s.2
uniprot id: A0A4W6CU82
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8187:LOC108879187
gene id: 8187:LOC108879187
uniprot id: A0A4W6G0J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108881730
gene id: 8187:LOC108881730
uniprot id: A0A4W6DL93
names: Similarity
messages: Belongs to the cystatin family.

8187:si:ch1073-396h14.1
gene id: 8187:si:ch1073-396h14.1
uniprot id: A0A4W6G2W9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:spop
gene id: 8187:spop
uniprot id: A0A4W6CLH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

8187:LOC108885149
gene id: 8187:LOC108885149
uniprot id: A0A4W6DIU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8187:serbp1a
gene id: 8187:serbp1a
uniprot id: A0A4W6D4P8
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

8187:LOC108898570
gene id: 8187:LOC108898570
uniprot id: A0A4W6CNN0
names: Subcellular Location Annotation
messages: Membrane

8187:prdm8b
gene id: 8187:prdm8b
uniprot id: A0A4W6EEV3
names: Subcellular Location Annotation
messages: Nucleus

8187:tmem135
gene id: 8187:tmem135
uniprot id: A0A4W6DB81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane

8187:LOC108897307
gene id: 8187:LOC108897307
uniprot id: A0A4W6D9U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

8187:LOC108899034
gene id: 8187:LOC108899034
uniprot id: A0A4W6ETT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

8187:furinb
gene id: 8187:furinb
uniprot id: A0A4W6EFT7
names: Similarity
messages: Belongs to the peptidase S8 family.

8187:tspan13a
gene id: 8187:tspan13a
uniprot id: A0A4W6BQ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:LOC108879160
gene id: 8187:LOC108879160
uniprot id: A0A4W6CM61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108892106
gene id: 8187:LOC108892106
uniprot id: A0A4W6C5U2
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8187:rimkla
gene id: 8187:rimkla
uniprot id: A0A4W6G842
names: Similarity
messages: Belongs to the RimK family.

8187:LOC108875554
gene id: 8187:LOC108875554
uniprot id: A0A4W6EKA9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8187:LOC108888029
gene id: 8187:LOC108888029
uniprot id: A0A4W6DAS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8187:slc41a2b
gene id: 8187:slc41a2b
uniprot id: A0A4W6EM54
uniprot id: A0A4W6EQ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8187:LOC108898576
gene id: 8187:LOC108898576
uniprot id: A0A4W6EHT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

8187:cyfip1
gene id: 8187:cyfip1
uniprot id: A0A4W6DYF1
names: Similarity
messages: Belongs to the CYFIP family.

8187:mtmr9
gene id: 8187:mtmr9
uniprot id: A0A4W6E4T5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8187:cdadc1
gene id: 8187:cdadc1
uniprot id: A0A4W6ELL5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

8187:snrpa1
gene id: 8187:snrpa1
uniprot id: A0A4W6D037
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

8187:frrs1b
gene id: 8187:frrs1b
uniprot id: A0A4W6ER35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

8187:LOC108887648
gene id: 8187:LOC108887648
uniprot id: A0A4W6CG89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

8187:spring1
gene id: 8187:spring1
uniprot id: A0A4W6EAX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

8187:txnrd3
gene id: 8187:txnrd3
uniprot id: A0A4W6FIE9
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

8187:paqr9
gene id: 8187:paqr9
uniprot id: A0A4W6F843
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8187:trim36
gene id: 8187:trim36
uniprot id: A0A4W6BTP1
names: Subcellular Location Annotation
messages: cytoskeleton

8187:pmm2
gene id: 8187:pmm2
uniprot id: A0A4W6CY13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

8187:nlk1
gene id: 8187:nlk1
uniprot id: A0A4W6DC71
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8187:tjp1b
gene id: 8187:tjp1b
uniprot id: A0A4W6D060
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8187:cers2b
gene id: 8187:cers2b
uniprot id: A0A4W6FR18
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8187:LOC108892883
gene id: 8187:LOC108892883
uniprot id: A0A4W6F0U2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:abcc8
gene id: 8187:abcc8
uniprot id: A0A4W6EM89
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

8187:arhgdig
gene id: 8187:arhgdig
uniprot id: A0A4W6C8T5
names: Similarity
messages: Belongs to the Rho GDI family.

8187:LOC108896867
gene id: 8187:LOC108896867
uniprot id: A0A4W6EHA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

8187:fam20b
gene id: 8187:fam20b
uniprot id: A0A4W6CYZ4
names: Similarity
messages: Belongs to the FAM20 family.

8187:LOC108879427
gene id: 8187:LOC108879427
uniprot id: A0A4W6DER1
names: Similarity
messages: Belongs to the cornifelin family.

8187:glod4
gene id: 8187:glod4
uniprot id: A0A4W6DKL6
names: Similarity
messages: Belongs to the glyoxalase I family.

8187:LOC108875790
gene id: 8187:LOC108875790
uniprot id: A0A4W6FRP7
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8187:crabp1a
gene id: 8187:crabp1a
uniprot id: A0A4W6CKX5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8187:kpna2
gene id: 8187:kpna2
uniprot id: A0A4W6BMI8
names: Similarity
messages: Belongs to the importin alpha family.

8187:zmpste24
gene id: 8187:zmpste24
uniprot id: A0A4W6F3B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

8187:LOC108887593
gene id: 8187:LOC108887593
uniprot id: A0A4W6BP94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8187:LOC108896266
gene id: 8187:LOC108896266
uniprot id: A0A4W6EZF5
names: Subcellular Location Annotation
messages: Membrane

8187:tmem242
gene id: 8187:tmem242
uniprot id: A0A4W6ENI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

8187:psmg2
gene id: 8187:psmg2
uniprot id: A0A4W6DZ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

8187:ndrg4
gene id: 8187:ndrg4
uniprot id: A0A4W6D199
uniprot id: A0A4W6D1M8
uniprot id: A0A4W6D1U1
uniprot id: A0A4W6D218
names: Similarity
messages: Belongs to the NDRG family.

8187:LOC108898096
gene id: 8187:LOC108898096
uniprot id: A0A4W6D797
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:slc25a24
gene id: 8187:slc25a24
uniprot id: A0A4W6F7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8187:nt5dc1
gene id: 8187:nt5dc1
uniprot id: A0A4W6DM25
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

8187:bbs2
gene id: 8187:bbs2
uniprot id: A0A4W6DDR0
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

8187:banf1
gene id: 8187:banf1
uniprot id: A0A4W6F2K4
names: Subcellular Location Annotation
messages: Nucleus

8187:efnb2a
gene id: 8187:efnb2a
uniprot id: A0A4W6DNS1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:mdh1b
gene id: 8187:mdh1b
uniprot id: A0A4W6G3R4
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

8187:adora2ab
gene id: 8187:adora2ab
uniprot id: A0A4W6CH13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8187:fstl4
gene id: 8187:fstl4
uniprot id: A0A4W6DVR2
names: Subcellular Location Annotation
messages: Membrane

8187:nsg1
gene id: 8187:nsg1
uniprot id: A0A4W6BSN1
names: Similarity
messages: Belongs to the NSG family.

8187:ucn3l
gene id: 8187:ucn3l
uniprot id: A0A4W6BVS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

8187:tmem186
gene id: 8187:tmem186
uniprot id: A0A4W6DFD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

8187:ndufa8
gene id: 8187:ndufa8
uniprot id: A0A4W6C072
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

8187:sst1.2
gene id: 8187:sst1.2
uniprot id: A0A4W6EWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

8187:cdk8
gene id: 8187:cdk8
uniprot id: A0A4W6DPT8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:pla2g10
gene id: 8187:pla2g10
uniprot id: A0A4W6C2R7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

8187:p2ry4
gene id: 8187:p2ry4
uniprot id: A0A4W6EJR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:si:dkey-43k4.5
gene id: 8187:si:dkey-43k4.5
uniprot id: A0A4W6BST0
names: Subcellular Location Annotation
messages: Membrane

8187:tpm1
gene id: 8187:tpm1
uniprot id: A0A4W6C6A9
uniprot id: A0A4W6CFW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8187:zic5
gene id: 8187:zic5
uniprot id: A0A4W6DEG4
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8187:LOC108886893
gene id: 8187:LOC108886893
uniprot id: A0A4W6DG65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8187:LOC108881511
gene id: 8187:LOC108881511
uniprot id: A0A4W6FYL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8187:gemin2
gene id: 8187:gemin2
uniprot id: A0A4W6FKB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

8187:zgc:112332
gene id: 8187:zgc:112332
uniprot id: A0A4W6FRK1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:eef1akmt1
gene id: 8187:eef1akmt1
uniprot id: A0A4W6EWC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

8187:mospd1
gene id: 8187:mospd1
uniprot id: A0A4W6FRG6
names: Subcellular Location Annotation
messages: Membrane

8187:gatad2b
gene id: 8187:gatad2b
uniprot id: A0A4W6CTP1
names: Subcellular Location Annotation
messages: Nucleus

8187:mapk8ip2
gene id: 8187:mapk8ip2
uniprot id: A0A4W6DMB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

8187:oip5
gene id: 8187:oip5
uniprot id: A0A4W6FEJ3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

8187:ppa2
gene id: 8187:ppa2
uniprot id: A0A4W6C740
names: Similarity
messages: Belongs to the PPase family.

8187:LOC108890037
gene id: 8187:LOC108890037
uniprot id: A0A4W6EH85
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8187:LOC108876177
gene id: 8187:LOC108876177
uniprot id: A0A4W6CW12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:ran
gene id: 8187:ran
uniprot id: A0A4W6DG47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

8187:orai2
gene id: 8187:orai2
uniprot id: A0A4W6DYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8187:rbfox2
gene id: 8187:rbfox2
uniprot id: A0A4W6FXA7
uniprot id: A0A4W6FYA5
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108896789
gene id: 8187:LOC108896789
uniprot id: A0A4W6EN64
names: Similarity
messages: Belongs to the TENT family.

8187:pex3
gene id: 8187:pex3
uniprot id: A0A4W6F9Y6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

8187:tspan36
gene id: 8187:tspan36
uniprot id: A0A4W6BMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:acad11
gene id: 8187:acad11
uniprot id: A0A4W6D0I2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8187:rnd3a
gene id: 8187:rnd3a
uniprot id: A0A4W6FE88
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

8187:LOC108873800
gene id: 8187:LOC108873800
uniprot id: A0A4W6CCE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

8187:avpr2b.1
gene id: 8187:avpr2b.1
uniprot id: A0A4W6FYT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8187:mapkap1
gene id: 8187:mapkap1
uniprot id: A0A4W6DGS9
names: Similarity
messages: Belongs to the SIN1 family.

8187:itga7
gene id: 8187:itga7
uniprot id: A0A4W6DVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8187:bysl
gene id: 8187:bysl
uniprot id: A0A4W6ENP0
names: Similarity
messages: Belongs to the bystin family.

8187:dgat2
gene id: 8187:dgat2
uniprot id: A0A4W6E9B6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:flad1
gene id: 8187:flad1
uniprot id: A0A4W6FTR8
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

8187:dlx4b
gene id: 8187:dlx4b
uniprot id: A0A4W6DGX8
names: Subcellular Location Annotation
messages: Nucleus

8187:abl2
gene id: 8187:abl2
uniprot id: A0A4W6G2S6
uniprot id: A0A4W6G4L5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8187:fam189b
gene id: 8187:fam189b
uniprot id: A0A4W6FTM4
names: Similarity
messages: Belongs to the ENTREP family.

8187:scamp2
gene id: 8187:scamp2
uniprot id: A0A4W6C7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8187:vamp1b
gene id: 8187:vamp1b
uniprot id: A0A4W6DH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8187:ndufs6
gene id: 8187:ndufs6
uniprot id: A0A4W6FJV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

8187:LOC108882829
gene id: 8187:LOC108882829
uniprot id: A0A4W6CVB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108873042
gene id: 8187:LOC108873042
uniprot id: A0A4W6F5Q3
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8187:kcna3a
gene id: 8187:kcna3a
uniprot id: A0A4W6CBH0
names: Subcellular Location Annotation
messages: Membrane

8187:dlg5a
gene id: 8187:dlg5a
uniprot id: A0A4W6D9G7
names: Similarity
messages: Belongs to the MAGUK family.

8187:cplx3b
gene id: 8187:cplx3b
uniprot id: A0A4W6G589
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8187:LOC108895501
gene id: 8187:LOC108895501
uniprot id: A0A4W6BVT4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8187:szrd1
gene id: 8187:szrd1
uniprot id: A0A4W6BND5
names: Similarity
messages: Belongs to the SZRD1 family.

8187:tspan12
gene id: 8187:tspan12
uniprot id: A0A4W6BZK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:pold2
gene id: 8187:pold2
uniprot id: A0A4W6FRS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

8187:LOC108883341
gene id: 8187:LOC108883341
uniprot id: A0A4W6CAR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8187:pbx3b
gene id: 8187:pbx3b
uniprot id: A0A4W6FQ58
uniprot id: A0A4W6FQD3
uniprot id: A0A4W6FQD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8187:ranbp9
gene id: 8187:ranbp9
uniprot id: A0A4W6BMG1
names: Similarity
messages: Belongs to the RANBP9/10 family.

8187:prkx
gene id: 8187:prkx
uniprot id: A0A4W6EFG3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:tmem251
gene id: 8187:tmem251
uniprot id: A0A4W6EGK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LYSET family.
messages: Membrane

8187:rpl18
gene id: 8187:rpl18
uniprot id: A0A4W6FJI7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

8187:gria2b
gene id: 8187:gria2b
uniprot id: A0A4W6FBH9
uniprot id: A0A4W6FBI7
uniprot id: A0A4W6FDX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8187:blcap
gene id: 8187:blcap
uniprot id: A0A4W6DGA5
names: Similarity
messages: Belongs to the BLCAP family.

8187:slc10a7
gene id: 8187:slc10a7
uniprot id: A0A4W6FBG9
uniprot id: A0A4W6FCJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8187:slc22a18
gene id: 8187:slc22a18
uniprot id: A0A4W6EFK1
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108892831
gene id: 8187:LOC108892831
uniprot id: A0A4W6EZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8187:LOC108892514
gene id: 8187:LOC108892514
uniprot id: A0A4W6DY64
names: Similarity
messages: Belongs to the actin family.

8187:pnx
gene id: 8187:pnx
uniprot id: A0A4W6EYA5
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108894949
gene id: 8187:LOC108894949
uniprot id: A0A4W6EE33
names: Similarity
messages: Belongs to the PROTOR family.

8187:LOC108875929
gene id: 8187:LOC108875929
uniprot id: A0A4W6FXP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8187:stk17b
gene id: 8187:stk17b
uniprot id: A0A4W6FSF1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108886689
gene id: 8187:LOC108886689
uniprot id: A0A4W6FF00
names: Similarity
messages: Belongs to the TTC9 family.

8187:LOC108878355
gene id: 8187:LOC108878355
uniprot id: A0A4W6FH95
names: Similarity
messages: Belongs to the CFAP157 family.

8187:pdlim1
gene id: 8187:pdlim1
uniprot id: A0A4W6CZI0
names: Subcellular Location Annotation
messages: Z line

8187:timp2a
gene id: 8187:timp2a
uniprot id: A0A4W6DSF0
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8187:sfxn5b
gene id: 8187:sfxn5b
uniprot id: A0A4W6FMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

8187:LOC108886468
gene id: 8187:LOC108886468
uniprot id: A0A4W6G344
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8187:LOC108875222
gene id: 8187:LOC108875222
uniprot id: A0A4W6E6M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8187:kif20a
gene id: 8187:kif20a
uniprot id: A0A4W6CPA0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8187:jpt2
gene id: 8187:jpt2
uniprot id: A0A4W6BP51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

8187:cp
gene id: 8187:cp
uniprot id: A0A4W6F6L5
uniprot id: A0A4W6F7E5
names: Similarity
messages: Belongs to the multicopper oxidase family.

8187:cdca8
gene id: 8187:cdca8
uniprot id: A0A4W6EYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

8187:htr2cl1
gene id: 8187:htr2cl1
uniprot id: A0A4W6CG94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:lnpep
gene id: 8187:lnpep
uniprot id: A0A4W6GA36
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8187:kcnab1a
gene id: 8187:kcnab1a
uniprot id: A0A4W6CPB5
uniprot id: A0A4W6CPL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8187:spega
gene id: 8187:spega
uniprot id: A0A4W6F542
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

8187:cdkn2aip
gene id: 8187:cdkn2aip
uniprot id: A0A4W6C302
names: Similarity
messages: Belongs to the CARF family.

8187:LOC108890584
gene id: 8187:LOC108890584
uniprot id: A0A4W6FJG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108893685
gene id: 8187:LOC108893685
uniprot id: A0A4W6FYI2
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

8187:cry1a
gene id: 8187:cry1a
uniprot id: A0A4W6G2Z9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8187:mapkapk3
gene id: 8187:mapkapk3
uniprot id: A0A4W6F7Y4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:tlcd1
gene id: 8187:tlcd1
uniprot id: A0A4W6DNE9
names: Subcellular Location Annotation
messages: Membrane

8187:wasf3b
gene id: 8187:wasf3b
uniprot id: A0A4W6DMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8187:dcaf11
gene id: 8187:dcaf11
uniprot id: A0A4W6BY26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

8187:ppifb
gene id: 8187:ppifb
uniprot id: A0A4W6ET34
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8187:cnn2
gene id: 8187:cnn2
uniprot id: A0A4W6F743
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

8187:mmp30
gene id: 8187:mmp30
uniprot id: A0A4W6E222
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8187:atp1b2b
gene id: 8187:atp1b2b
uniprot id: A0A4W6FW85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8187:LOC108883654
gene id: 8187:LOC108883654
uniprot id: A0A4W6F4U8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8187:znf503
gene id: 8187:znf503
uniprot id: A0A4W6DGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8187:akap8l
gene id: 8187:akap8l
uniprot id: A0A4W6G8A5
names: Similarity
messages: Belongs to the AKAP95 family.

8187:atp6v1f
gene id: 8187:atp6v1f
uniprot id: A0A4W6DGE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8187:gjb8
gene id: 8187:gjb8
uniprot id: A0A4W6DN56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8187:eef1g
gene id: 8187:eef1g
uniprot id: A0A4W6DIU8
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

8187:LOC108891918
gene id: 8187:LOC108891918
uniprot id: A0A4W6E2X2
uniprot id: A0A4W6E2X8
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8187:antxr2a
gene id: 8187:antxr2a
uniprot id: A0A4W6EFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8187:traf4a
gene id: 8187:traf4a
uniprot id: A0A4W6DL37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8187:slco4a1
gene id: 8187:slco4a1
uniprot id: A0A4W6BTK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:lingo3a
gene id: 8187:lingo3a
uniprot id: A0A4W6FRI9
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108896703
gene id: 8187:LOC108896703
uniprot id: A0A4W6EB38
names: Similarity
messages: Belongs to the FAM151 family.

8187:LOC108876938
gene id: 8187:LOC108876938
uniprot id: A0A4W6ER31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8187:rps15
gene id: 8187:rps15
uniprot id: A0A4W6F7X1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Component of the small ribosomal subunit.

8187:LOC108891256
gene id: 8187:LOC108891256
uniprot id: A0A4W6EZ75
names: Similarity
messages: Belongs to the AAA ATPase family.

8187:gclm
gene id: 8187:gclm
uniprot id: A0A4W6G3C8
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

8187:LOC108879875
gene id: 8187:LOC108879875
uniprot id: A0A4W6CS76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

8187:tafazzin
gene id: 8187:tafazzin
uniprot id: A0A4W6EQG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

8187:kcnk10b
gene id: 8187:kcnk10b
uniprot id: A0A4W6EMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8187:tpi1a
gene id: 8187:tpi1a
uniprot id: A0A4W6FNQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8187:dnajb12b
gene id: 8187:dnajb12b
uniprot id: A0A4W6EWV0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:snrpg
gene id: 8187:snrpg
uniprot id: A0A4W6BYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

8187:rhbg
gene id: 8187:rhbg
uniprot id: A0A4W6D459
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8187:uxs1
gene id: 8187:uxs1
uniprot id: A0A4W6FI61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

8187:kcna7
gene id: 8187:kcna7
uniprot id: A0A4W6C814
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108896630
gene id: 8187:LOC108896630
uniprot id: A0A4W6BMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8187:LOC108890713
gene id: 8187:LOC108890713
uniprot id: A0A4W6FJL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:gorab
gene id: 8187:gorab
uniprot id: A0A4W6D4U3
names: Similarity
messages: Belongs to the GORAB family.

8187:LOC108883584
gene id: 8187:LOC108883584
uniprot id: A0A4W6E9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8187:nr1d2a
gene id: 8187:nr1d2a
uniprot id: A0A4W6G4P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8187:carmil3
gene id: 8187:carmil3
uniprot id: A0A4W6CTQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

8187:LOC108877586
gene id: 8187:LOC108877586
uniprot id: A0A4W6DM81
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:gngt1
gene id: 8187:gngt1
uniprot id: A0A4W6ER05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8187:matk
gene id: 8187:matk
uniprot id: A0A4W6FRV5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8187:LOC108872509
gene id: 8187:LOC108872509
uniprot id: A0A4W6G137
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:fam49bb
gene id: 8187:fam49bb
uniprot id: A0A4W6CS44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

8187:rdh12l
gene id: 8187:rdh12l
uniprot id: A0A4W6E0W3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:sumo1
gene id: 8187:sumo1
uniprot id: A0A4W6ETU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8187:gins3
gene id: 8187:gins3
uniprot id: A0A4W6D113
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

8187:myadmb
gene id: 8187:myadmb
uniprot id: A0A4W6BS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

8187:rnf114
gene id: 8187:rnf114
uniprot id: A0A4W6F9Y3
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.
messages: Nucleus

8187:adipor1a
gene id: 8187:adipor1a
uniprot id: A0A4W6FWY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8187:rtcb
gene id: 8187:rtcb
uniprot id: A0A4W6F4G4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

8187:prpsap1
gene id: 8187:prpsap1
uniprot id: A0A4W6BXX3
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8187:LOC108893426
gene id: 8187:LOC108893426
uniprot id: A0A4W6FRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8187:flot1b
gene id: 8187:flot1b
uniprot id: A0A4W6CDJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

8187:vti1a
gene id: 8187:vti1a
uniprot id: A0A4W6C1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

8187:LOC108896740
gene id: 8187:LOC108896740
uniprot id: A0A4W6CV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

8187:zgc:165573
gene id: 8187:zgc:165573
uniprot id: A0A4W6C7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

8187:tarbp2
gene id: 8187:tarbp2
uniprot id: A0A4W6EE26
uniprot id: A0A4W6EGA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC.

8187:rbks
gene id: 8187:rbks
uniprot id: A0A4W6FAC3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

8187:nfil3-4
gene id: 8187:nfil3-4
uniprot id: A0A4W6FSY2
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8187:LOC108881949
gene id: 8187:LOC108881949
uniprot id: A0A4W6EQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108881412
gene id: 8187:LOC108881412
uniprot id: A0A4W6G434
uniprot id: A0A4W6G5A2
uniprot id: A0A4W6G603
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8187:usp45
gene id: 8187:usp45
uniprot id: A0A4W6E534
names: Similarity
messages: Belongs to the peptidase C19 family.

8187:LOC108886716
gene id: 8187:LOC108886716
uniprot id: A0A4W6FF51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

8187:grin1a
gene id: 8187:grin1a
uniprot id: A0A4W6FCP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8187:hbs1l
gene id: 8187:hbs1l
uniprot id: A0A4W6EBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm

8187:samd4a
gene id: 8187:samd4a
uniprot id: A0A4W6EF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

8187:stam
gene id: 8187:stam
uniprot id: A0A4W6EVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

8187:atp1b1b
gene id: 8187:atp1b1b
uniprot id: A0A4W6CZC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8187:cckb
gene id: 8187:cckb
uniprot id: A0A4W6FP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

8187:zgc:110366
gene id: 8187:zgc:110366
uniprot id: A0A4W6E4Q9
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8187:tbx2b
gene id: 8187:tbx2b
uniprot id: A0A4W6C5X4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8187:kcnb1
gene id: 8187:kcnb1
uniprot id: A0A4W6D6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: dendrite
messages: sarcolemma
messages: synaptosome

8187:LOC108900100
gene id: 8187:LOC108900100
uniprot id: A0A4W6CWQ9
uniprot id: A0A4W6CWU1
uniprot id: A0A4W6CWV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8187:gdf9
gene id: 8187:gdf9
uniprot id: A0A4W6E7B7
names: Similarity
messages: Belongs to the TGF-beta family.

8187:rtn3
gene id: 8187:rtn3
uniprot id: A0A4W6ECM9
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:aars1
gene id: 8187:aars1
uniprot id: A0A4W6DLH0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

8187:gnpat2
gene id: 8187:gnpat2
uniprot id: A0A4W6EJ26
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

8187:fam131aa
gene id: 8187:fam131aa
uniprot id: A0A4W6DQL7
names: Similarity
messages: Belongs to the FAM131 family.

8187:mtfr2
gene id: 8187:mtfr2
uniprot id: A0A4W6EBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

8187:vgll4l
gene id: 8187:vgll4l
uniprot id: A0A4W6FQ65
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8187:LOC108883834
gene id: 8187:LOC108883834
uniprot id: A0A4W6BQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8187:cenpk
gene id: 8187:cenpk
uniprot id: A0A4W6C2R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

8187:insm1a
gene id: 8187:insm1a
uniprot id: A0A4W6FTH3
names: Subcellular Location Annotation
messages: Nucleus

8187:dnm1a
gene id: 8187:dnm1a
uniprot id: A0A4W6CWV0
uniprot id: A0A4W6CXG3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8187:ppp1r12a
gene id: 8187:ppp1r12a
uniprot id: A0A4W6C7I3
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

8187:gsc
gene id: 8187:gsc
uniprot id: A0A4W6CBQ0
names: Subcellular Location Annotation
messages: Nucleus

8187:si:dkey-175m17.7
gene id: 8187:si:dkey-175m17.7
uniprot id: A0A4W6F2H7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8187:lsm1
gene id: 8187:lsm1
uniprot id: A0A4W6FUL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

8187:LOC108876740
gene id: 8187:LOC108876740
uniprot id: A0A4W6CSG1
names: Subcellular Location Annotation
messages: Membrane

8187:znf703
gene id: 8187:znf703
uniprot id: A0A4W6E502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8187:lmod1b
gene id: 8187:lmod1b
uniprot id: A0A4W6C983
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

8187:lhx4
gene id: 8187:lhx4
uniprot id: A0A4W6FTA5
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108900646
gene id: 8187:LOC108900646
uniprot id: A0A4W6FEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

8187:kif25
gene id: 8187:kif25
uniprot id: A0A4W6DEM2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8187:ccnh
gene id: 8187:ccnh
uniprot id: A0A4W6G9J7
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

8187:pgap1
gene id: 8187:pgap1
uniprot id: A0A4W6FRT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

8187:LOC108880373
gene id: 8187:LOC108880373
uniprot id: A0A4W6DW20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8187:arpc1a
gene id: 8187:arpc1a
uniprot id: A0A4W6CRC1
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

8187:spats2
gene id: 8187:spats2
uniprot id: A0A4W6ED85
names: Similarity
messages: Belongs to the SPATS2 family.

8187:nap1l1
gene id: 8187:nap1l1
uniprot id: A0A4W6E5C4
uniprot id: A0A4W6FYB6
uniprot id: A0A4W6FYC1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8187:tmem41aa
gene id: 8187:tmem41aa
uniprot id: A0A4W6FKM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

8187:haus1
gene id: 8187:haus1
uniprot id: A0A4W6FVX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

8187:dcp1a
gene id: 8187:dcp1a
uniprot id: A0A4W6BWQ0
names: Similarity
messages: Belongs to the DCP1 family.

8187:gatad2ab
gene id: 8187:gatad2ab
uniprot id: A0A4W6DC06
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108878817
gene id: 8187:LOC108878817
uniprot id: A0A4W6F0R4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:cavin2a
gene id: 8187:cavin2a
uniprot id: A0A4W6CXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8187:pyyb
gene id: 8187:pyyb
uniprot id: A0A4W6DFE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

8187:LOC108899892
gene id: 8187:LOC108899892
uniprot id: A0A4W6FK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

8187:LOC108891851
gene id: 8187:LOC108891851
uniprot id: A0A4W6DQI2
names: Similarity
messages: Belongs to the TPPP family.

8187:LOC108899832
gene id: 8187:LOC108899832
uniprot id: A0A4W6DZQ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:cdk7
gene id: 8187:cdk7
uniprot id: A0A4W6G971
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

8187:pde10a
gene id: 8187:pde10a
uniprot id: A0A4W6EAF1
uniprot id: A0A4W6ECV1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8187:LOC108897579
gene id: 8187:LOC108897579
uniprot id: A0A4W6G5S6
names: Similarity
messages: Belongs to the mTERF family.

8187:cuedc2
gene id: 8187:cuedc2
uniprot id: A0A4W6E9V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

8187:chmp7
gene id: 8187:chmp7
uniprot id: A0A4W6FHF1
names: Similarity
messages: Belongs to the SNF7 family.

8187:LOC108884949
gene id: 8187:LOC108884949
uniprot id: A0A4W6CN87
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8187:irx5a
gene id: 8187:irx5a
uniprot id: A0A4W6ECK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8187:LOC108887924
gene id: 8187:LOC108887924
uniprot id: A0A4W6CEU2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8187:aars2
gene id: 8187:aars2
uniprot id: A0A4W6DKH0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

8187:camsap2a
gene id: 8187:camsap2a
uniprot id: A0A4W6D726
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8187:LOC108900588
gene id: 8187:LOC108900588
uniprot id: A0A4W6BZE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8187:osbpl5
gene id: 8187:osbpl5
uniprot id: A0A4W6EKN2
names: Similarity
messages: Belongs to the OSBP family.

8187:rbx1
gene id: 8187:rbx1
uniprot id: A0A4W6DF30
names: Similarity
messages: Belongs to the RING-box family.

8187:peli2
gene id: 8187:peli2
uniprot id: A0A4W6F2T3
names: Similarity
messages: Belongs to the pellino family.

8187:vgll4b
gene id: 8187:vgll4b
uniprot id: A0A4W6EXP4
uniprot id: A0A4W6F0P2
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8187:gpt
gene id: 8187:gpt
uniprot id: A0A4W6BVK5
uniprot id: A0A4W6BVP1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8187:LOC108873894
gene id: 8187:LOC108873894
uniprot id: A0A4W6CLJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8187:hapstr1b
gene id: 8187:hapstr1b
uniprot id: A0A4W6CRG4
names: Subcellular Location Annotation
messages: Nucleus

8187:bud23
gene id: 8187:bud23
uniprot id: A0A4W6CSW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108889869
gene id: 8187:LOC108889869
uniprot id: A0A4W6DSI8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

8187:ndufa10
gene id: 8187:ndufa10
uniprot id: A0A4W6G2G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

8187:tmed2
gene id: 8187:tmed2
uniprot id: A0A4W6DE27
uniprot id: A0A4W6DEK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8187:bcl2l10
gene id: 8187:bcl2l10
uniprot id: A0A4W6FHH7
names: Similarity
messages: Belongs to the Bcl-2 family.

8187:gpr180
gene id: 8187:gpr180
uniprot id: A0A4W6EWA9
names: Subcellular Location Annotation
messages: Membrane

8187:prox2
gene id: 8187:prox2
uniprot id: A0A4W6EV06
names: Subcellular Location Annotation
messages: Nucleus

8187:ess2
gene id: 8187:ess2
uniprot id: A0A4W6CQ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

8187:inhbb
gene id: 8187:inhbb
uniprot id: A0A4W6EIW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

8187:LOC108882966
gene id: 8187:LOC108882966
uniprot id: A0A4W6EA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:LOC108877590
gene id: 8187:LOC108877590
uniprot id: A0A4W6DKK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

8187:gldc
gene id: 8187:gldc
uniprot id: A0A4W6EIU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8187:LOC108876453
gene id: 8187:LOC108876453
uniprot id: A0A4W6DZN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

8187:meox1
gene id: 8187:meox1
uniprot id: A0A4W6G806
names: Subcellular Location Annotation
messages: Nucleus

8187:hpse2
gene id: 8187:hpse2
uniprot id: A0A4W6CBB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

8187:fgf5
gene id: 8187:fgf5
uniprot id: A0A4W6EGA3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:b3gnt9
gene id: 8187:b3gnt9
uniprot id: A0A4W6DDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:zgc:92606
gene id: 8187:zgc:92606
uniprot id: A0A4W6D8X5
names: Similarity
messages: Belongs to the ATG8 family.

8187:erap2
gene id: 8187:erap2
uniprot id: A0A4W6GC17
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8187:LOC108876089
gene id: 8187:LOC108876089
uniprot id: A0A4W6DLZ2
names: Similarity
messages: Belongs to the CDR2 family.

8187:med18
gene id: 8187:med18
uniprot id: A0A4W6DGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8187:cct7
gene id: 8187:cct7
uniprot id: A0A4W6ELJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

8187:gpr184
gene id: 8187:gpr184
uniprot id: A0A4W6ER70
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:fgf22
gene id: 8187:fgf22
uniprot id: A0A4W6C5E3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:tmem17
gene id: 8187:tmem17
uniprot id: A0A4W6ERD7
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108900039
gene id: 8187:LOC108900039
uniprot id: A0A4W6DXU6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8187:hspa13
gene id: 8187:hspa13
uniprot id: A0A4W6CTF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Binds UBQLN2.
messages: Endoplasmic reticulum
messages: Has peptide-independent ATPase activity.
messages: Microsome

8187:zar1
gene id: 8187:zar1
uniprot id: A0A4W6E1Z3
names: Similarity
messages: Belongs to the ZAR1 family.

8187:ptger4a
gene id: 8187:ptger4a
uniprot id: A0A4W6CJL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

8187:gatad1
gene id: 8187:gatad1
uniprot id: A0A4W6DX90
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108894957
gene id: 8187:LOC108894957
uniprot id: A0A4W6EE82
uniprot id: A0A4W6EGG9
uniprot id: A0A4W6EIQ9
uniprot id: A0A4W6EJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

8187:pecam1b
gene id: 8187:pecam1b
uniprot id: A0A4W6DAY7
uniprot id: A0A4W6DAZ0
uniprot id: A0A4W6DBD8
uniprot id: A0A4W6DBE2
uniprot id: A0A4W6DBU0
uniprot id: A0A4W6DBU5
names: Subcellular Location Annotation
messages: Membrane

8187:f2r
gene id: 8187:f2r
uniprot id: A0A4W6G9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:anapc15
gene id: 8187:anapc15
uniprot id: A0A4W6F857
names: Similarity
messages: Belongs to the APC15 family.

8187:LOC108896210
gene id: 8187:LOC108896210
uniprot id: A0A4W6CT84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108877910
gene id: 8187:LOC108877910
uniprot id: A0A4W6F4Z4
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:fhip1b
gene id: 8187:fhip1b
uniprot id: A0A4W6DIU4
names: Similarity
messages: Belongs to the FHIP family.

8187:inpp5ka
gene id: 8187:inpp5ka
uniprot id: A0A4W6BWN4
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

8187:LOC108899478
gene id: 8187:LOC108899478
uniprot id: A0A4W6BW16
names: Similarity
messages: Belongs to the MS4A family.

8187:fam114a2
gene id: 8187:fam114a2
uniprot id: A0A4W6DN79
uniprot id: A0A4W6DN83
names: Similarity
messages: Belongs to the FAM114 family.

8187:prdm13
gene id: 8187:prdm13
uniprot id: A0A4W6E6H9
names: Subcellular Location Annotation
messages: Nucleus

8187:rad23aa
gene id: 8187:rad23aa
uniprot id: A0A4W6E975
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

8187:slc18b1
gene id: 8187:slc18b1
uniprot id: A0A4W6EWD6
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108892144
gene id: 8187:LOC108892144
uniprot id: A0A4W6DS24
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:tspan9a
gene id: 8187:tspan9a
uniprot id: A0A4W6E1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:utp23
gene id: 8187:utp23
uniprot id: A0A4W6ET41
names: Subcellular Location Annotation
messages: nucleolus

8187:mfap1
gene id: 8187:mfap1
uniprot id: A0A4W6C0B2
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

8187:LOC108883150
gene id: 8187:LOC108883150
uniprot id: M1S1U1
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

8187:robo1
gene id: 8187:robo1
uniprot id: A0A4W6DTH9
names: Subcellular Location Annotation
messages: Membrane

8187:nudt1
gene id: 8187:nudt1
uniprot id: A0A4W6CPA8
uniprot id: A0A4W6CPH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

8187:calr3a
gene id: 8187:calr3a
uniprot id: A0A4W6DVC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

8187:LOC108874416
gene id: 8187:LOC108874416
uniprot id: A0A4W6EWD0
names: Subcellular Location Annotation
messages: Membrane

8187:mrps2
gene id: 8187:mrps2
uniprot id: A0A4W6F191
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

8187:drd3
gene id: 8187:drd3
uniprot id: A0A4W6DLP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:aacs
gene id: 8187:aacs
uniprot id: A0A4W6EH00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

8187:trdmt1
gene id: 8187:trdmt1
uniprot id: A0A4W6F1T0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

8187:LOC108897021
gene id: 8187:LOC108897021
uniprot id: A0A4W6DU95
names: Similarity
messages: Belongs to the ZC3H12 family.

8187:boka
gene id: 8187:boka
uniprot id: A0A4W6DD17
names: Similarity
messages: Belongs to the Bcl-2 family.

8187:sox21b
gene id: 8187:sox21b
uniprot id: A0A4W6FYB2
names: Subcellular Location Annotation
messages: Nucleus

8187:septin5b
gene id: 8187:septin5b
uniprot id: A0A4W6FB34
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8187:galr2b
gene id: 8187:galr2b
uniprot id: A0A4W6C2S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8187:cd151
gene id: 8187:cd151
uniprot id: A0A4W6DXD5
uniprot id: A0A4W6DXT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:sdhaf1
gene id: 8187:sdhaf1
uniprot id: A0A4W6DZ99
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

8187:atp2a2a
gene id: 8187:atp2a2a
uniprot id: A0A4W6G821
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8187:snx19b
gene id: 8187:snx19b
uniprot id: A0A4W6CNU8
names: Similarity
messages: Belongs to the sorting nexin family.

8187:nlgn2b
gene id: 8187:nlgn2b
uniprot id: A0A4W6F1L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8187:LOC108900611
gene id: 8187:LOC108900611
uniprot id: A0A4W6CNV7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:LOC108897989
gene id: 8187:LOC108897989
uniprot id: A0A4W6DHD4
names: Similarity
messages: Belongs to the peptidase C2 family.

8187:tpm4a
gene id: 8187:tpm4a
uniprot id: A0A4W6G3P7
uniprot id: A0A4W6G4U7
uniprot id: A0A4W6G4V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8187:mysm1
gene id: 8187:mysm1
uniprot id: A0A4W6CUY3
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

8187:lrfn5a
gene id: 8187:lrfn5a
uniprot id: A0A4W6DPI5
names: Subcellular Location Annotation
messages: Membrane

8187:gng12b
gene id: 8187:gng12b
uniprot id: A0A4W6CX21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8187:LOC108873032
gene id: 8187:LOC108873032
uniprot id: A0A4W6FEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8187:fam120c
gene id: 8187:fam120c
uniprot id: A0A4W6FDG8
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

8187:LOC108891836
gene id: 8187:LOC108891836
uniprot id: A0A4W6DQH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:pdcd10a
gene id: 8187:pdcd10a
uniprot id: A0A4W6E5H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8187:rpl11
gene id: 8187:rpl11
uniprot id: A0A4W6DPI8
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

8187:kirrel1b
gene id: 8187:kirrel1b
uniprot id: A0A4W6BNR3
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108894080
gene id: 8187:LOC108894080
uniprot id: A0A4W6F755
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8187:LOC108893578
gene id: 8187:LOC108893578
uniprot id: A0A4W6D5J8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8187:grk7a
gene id: 8187:grk7a
uniprot id: A0A4W6FH39
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8187:LOC108887835
gene id: 8187:LOC108887835
uniprot id: A0A4W6EP27
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8187:pyroxd1
gene id: 8187:pyroxd1
uniprot id: A0A4W6DYG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

8187:golm2
gene id: 8187:golm2
uniprot id: A0A4W6CVG8
uniprot id: A0A4W6CVP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

8187:cog1
gene id: 8187:cog1
uniprot id: A0A4W6D4P1
names: Similarity
messages: Belongs to the COG1 family.

8187:grm2a
gene id: 8187:grm2a
uniprot id: A0A4W6F9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8187:gdpd5b
gene id: 8187:gdpd5b
uniprot id: A0A4W6CTH2
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8187:LOC108893680
gene id: 8187:LOC108893680
uniprot id: A0A4W6FKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:s100t
gene id: 8187:s100t
uniprot id: A0A4W6FTZ5
names: Similarity
messages: Belongs to the S-100 family.

8187:gnl2
gene id: 8187:gnl2
uniprot id: A0A4W6C135
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

8187:ndrg1a
gene id: 8187:ndrg1a
uniprot id: A0A4W6CSD8
names: Similarity
messages: Belongs to the NDRG family.

8187:cdc42ep1a
gene id: 8187:cdc42ep1a
uniprot id: A0A4W6BR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8187:si:ch73-288o11.4
gene id: 8187:si:ch73-288o11.4
uniprot id: A0A4W6DZ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

8187:LOC108884407
gene id: 8187:LOC108884407
uniprot id: A0A4W6G4M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108886968
gene id: 8187:LOC108886968
uniprot id: A0A4W6FQP5
names: Subcellular Location Annotation
messages: Nucleus

8187:cnot3b
gene id: 8187:cnot3b
uniprot id: A0A4W6FPP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

8187:tmem231
gene id: 8187:tmem231
uniprot id: A0A4W6EMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

8187:smpd5
gene id: 8187:smpd5
uniprot id: A0A4W6DLA7
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

8187:LOC108884305
gene id: 8187:LOC108884305
uniprot id: A0A4W6BUA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8187:LOC108901190
gene id: 8187:LOC108901190
uniprot id: A0A4W6ER20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8187:crebl2
gene id: 8187:crebl2
uniprot id: A0A4W6F1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

8187:calr
gene id: 8187:calr
uniprot id: A0A4W6G301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

8187:si:ch211-220i18.4
gene id: 8187:si:ch211-220i18.4
uniprot id: A0A4W6D9S4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:skap1
gene id: 8187:skap1
uniprot id: A0A4W6DYZ5
names: Similarity
messages: Belongs to the SKAP family.

8187:slc10a4
gene id: 8187:slc10a4
uniprot id: A0A4W6E642
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

8187:lztfl1
gene id: 8187:lztfl1
uniprot id: A0A4W6E2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

8187:tbc1d31
gene id: 8187:tbc1d31
uniprot id: A0A4W6ECX7
names: Function
names: Subcellular Location Annotation
messages: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
messages: centriolar satellite
messages: cilium basal body

8187:znf598
gene id: 8187:znf598
uniprot id: A0A4W6CAA0
names: Similarity
messages: Belongs to the ZNF598/HEL2 family.

8187:cdca7b
gene id: 8187:cdca7b
uniprot id: A0A4W6EUI5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:nop10
gene id: 8187:nop10
uniprot id: A0A4W6C8P0
names: Similarity
messages: Belongs to the NOP10 family.

8187:mvda
gene id: 8187:mvda
uniprot id: A0A4W6C7S7
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

8187:tpm4b
gene id: 8187:tpm4b
uniprot id: A0A4W6EEJ3
uniprot id: A0A4W6EH60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8187:dennd6aa
gene id: 8187:dennd6aa
uniprot id: A0A4W6FWJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

8187:use1
gene id: 8187:use1
uniprot id: A0A4W6FQX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108893706
gene id: 8187:LOC108893706
uniprot id: A0A4W6FID3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8187:dars2
gene id: 8187:dars2
uniprot id: A0A4W6BUK5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

8187:tmem50a
gene id: 8187:tmem50a
uniprot id: A0A4W6DJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

8187:sgk3
gene id: 8187:sgk3
uniprot id: A0A4W6DSP4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

8187:LOC108877389
gene id: 8187:LOC108877389
uniprot id: A0A4W6EE88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8187:LOC108877717
gene id: 8187:LOC108877717
uniprot id: A0A4W6F2M4
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

8187:scfd1
gene id: 8187:scfd1
uniprot id: A0A4W6DIP0
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8187:elovl4a
gene id: 8187:elovl4a
uniprot id: A0A4W6EFR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Oligomer.

8187:ovol1a
gene id: 8187:ovol1a
uniprot id: A0A4W6C871
names: Subcellular Location Annotation
messages: Nucleus

8187:ndufa13
gene id: 8187:ndufa13
uniprot id: A0A4W6EBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

8187:scoca
gene id: 8187:scoca
uniprot id: A0A4W6DET0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

8187:LOC108883875
gene id: 8187:LOC108883875
uniprot id: A0A4W6C9C2
names: Similarity
messages: Belongs to the GORASP family.

8187:pigl
gene id: 8187:pigl
uniprot id: A0A4W6ET57
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

8187:LOC108883800
gene id: 8187:LOC108883800
uniprot id: A0A4W6FQH0
names: Subcellular Location Annotation
messages: Membrane

8187:elp4
gene id: 8187:elp4
uniprot id: A0A4W6CFN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

8187:cryba2b
gene id: 8187:cryba2b
uniprot id: A0A4W6G6N3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:dyrk4
gene id: 8187:dyrk4
uniprot id: A0A4W6C1K2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8187:sst1.1
gene id: 8187:sst1.1
uniprot id: A0A4W6EXE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

8187:nus1
gene id: 8187:nus1
uniprot id: A0A4W6DQS5
names: Similarity
messages: Belongs to the UPP synthase family.

8187:pspc1
gene id: 8187:pspc1
uniprot id: A0A4W6FE71
names: Subcellular Location Annotation
messages: Nucleus speckle

8187:LOC108900745
gene id: 8187:LOC108900745
uniprot id: A0A4W6DGB7
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

8187:LOC108885382
gene id: 8187:LOC108885382
uniprot id: A0A4W6D3U3
names: Subcellular Location Annotation
messages: Nucleus

8187:hsf2
gene id: 8187:hsf2
uniprot id: A0A4W6DQP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

8187:stpg1
gene id: 8187:stpg1
uniprot id: A0A4W6BQC9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:LOC108873554
gene id: 8187:LOC108873554
uniprot id: A0A4W6E324
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8187:thoc6
gene id: 8187:thoc6
uniprot id: A0A4W6FAW9
names: Similarity
messages: Belongs to the WD repeat THOC6 family.

8187:tomm40l
gene id: 8187:tomm40l
uniprot id: A0A4W6EI18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8187:si:ch73-352p4.8
gene id: 8187:si:ch73-352p4.8
uniprot id: A0A4W6C3W3
names: Subcellular Location Annotation
messages: Membrane

8187:strn4
gene id: 8187:strn4
uniprot id: A0A4W6ET11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

8187:sfpq
gene id: 8187:sfpq
uniprot id: A0A4W6DP02
uniprot id: A0A4W6DP65
names: Subcellular Location Annotation
messages: Nucleus speckle

8187:fgd5a
gene id: 8187:fgd5a
uniprot id: A0A4W6FDU6
names: Subcellular Location Annotation
messages: cytoskeleton

8187:stx18
gene id: 8187:stx18
uniprot id: A0A4W6C0K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

8187:itm2cb
gene id: 8187:itm2cb
uniprot id: A0A4W6DLQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8187:hars
gene id: 8187:hars
uniprot id: A0A4W6E109
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

8187:LOC108873446
gene id: 8187:LOC108873446
uniprot id: A0A4W6DXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

8187:LOC108877697
gene id: 8187:LOC108877697
uniprot id: A0A4W6F6P8
names: Similarity
messages: Belongs to the histone H3 family.

8187:nppc
gene id: 8187:nppc
uniprot id: A0A4W6D809
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8187:lta4h
gene id: 8187:lta4h
uniprot id: A0A4W6DDM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

8187:yes1
gene id: 8187:yes1
uniprot id: A0A4W6EYW4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8187:slc52a2
gene id: 8187:slc52a2
uniprot id: A0A4W6DVE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8187:si:dkey-1k23.3
gene id: 8187:si:dkey-1k23.3
uniprot id: A0A4W6E977
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8187:qars1
gene id: 8187:qars1
uniprot id: A0A4W6EQV4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8187:mief2
gene id: 8187:mief2
uniprot id: A0A4W6CRT0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8187:cfap126
gene id: 8187:cfap126
uniprot id: A0A4W6E674
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

8187:snx10b
gene id: 8187:snx10b
uniprot id: A0A4W6DJY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8187:fgf16
gene id: 8187:fgf16
uniprot id: A0A4W6E5L8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:acot20
gene id: 8187:acot20
uniprot id: A0A4W6FXL9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8187:cyldb
gene id: 8187:cyldb
uniprot id: A0A4W6EUQ6
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

8187:slc47a1
gene id: 8187:slc47a1
uniprot id: A0A4W6DAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8187:kcnj8
gene id: 8187:kcnj8
uniprot id: A0A4W6D0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8187:LOC108887854
gene id: 8187:LOC108887854
uniprot id: A0A4W6F5J7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:faslg
gene id: 8187:faslg
uniprot id: A0A4W6CYR9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8187:ropn1l
gene id: 8187:ropn1l
uniprot id: A0A4W6FT65
uniprot id: A0A4W6FT98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ropporin family.
messages: flagellum

8187:upp1
gene id: 8187:upp1
uniprot id: A0A4W6DQD2
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

8187:tln2a
gene id: 8187:tln2a
uniprot id: A0A4W6FU22
names: Subcellular Location Annotation
messages: cytoskeleton

8187:c1galt1lb
gene id: 8187:c1galt1lb
uniprot id: A0A4W6EKI3
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108900513
gene id: 8187:LOC108900513
uniprot id: A0A4W6CPX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:acss1
gene id: 8187:acss1
uniprot id: A0A4W6EZS6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8187:emc9
gene id: 8187:emc9
uniprot id: A0A4W6G3L6
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

8187:prr15lb
gene id: 8187:prr15lb
uniprot id: A0A4W6E1J8
names: Similarity
messages: Belongs to the PRR15 family.

8187:tmem245
gene id: 8187:tmem245
uniprot id: A0A4W6CEL3
uniprot id: A0A4W6CJM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

8187:eomesa
gene id: 8187:eomesa
uniprot id: A0A4W6DSG3
uniprot id: A0A4W6DTX9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8187:LOC108895651
gene id: 8187:LOC108895651
uniprot id: A0A4W6CYX5
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108888501
gene id: 8187:LOC108888501
uniprot id: A0A4W6F0T1
uniprot id: A0A4W6F3J2
names: Similarity
messages: Belongs to the TEX28 family.

8187:prmt3
gene id: 8187:prmt3
uniprot id: A0A4W6ELY6
names: Subcellular Location Annotation
messages: Cytoplasm

8187:enoph1
gene id: 8187:enoph1
uniprot id: A0A4W6CWX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

8187:lrp3
gene id: 8187:lrp3
uniprot id: A0A4W6G1F3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:homezb
gene id: 8187:homezb
uniprot id: A0A4W6BJC8
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108874758
gene id: 8187:LOC108874758
uniprot id: A0A4W6G204
names: Similarity
messages: Belongs to the DNase I family.

8187:grwd1
gene id: 8187:grwd1
uniprot id: A0A4W6D3P5
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108879028
gene id: 8187:LOC108879028
uniprot id: A0A4W6D3Z3
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:rras2
gene id: 8187:rras2
uniprot id: A0A4W6DPH2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8187:LOC108874755
gene id: 8187:LOC108874755
uniprot id: A0A4W6G0E5
names: Similarity
messages: Belongs to the MS4A family.

8187:tcp11l1
gene id: 8187:tcp11l1
uniprot id: A0A4W6EIY0
names: Similarity
messages: Belongs to the TCP11 family.

8187:cdc42ep3
gene id: 8187:cdc42ep3
uniprot id: A0A4W6D251
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8187:zc3h12ab
gene id: 8187:zc3h12ab
uniprot id: A0A4W6CCM9
names: Similarity
messages: Belongs to the ZC3H12 family.

8187:cux1b
gene id: 8187:cux1b
uniprot id: A0A4W6CSM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

8187:mrps31
gene id: 8187:mrps31
uniprot id: A0A4W6BUN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

8187:chl1b
gene id: 8187:chl1b
uniprot id: A0A4W6FWA9
uniprot id: A0A4W6FWI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

8187:LOC108896901
gene id: 8187:LOC108896901
uniprot id: A0A4W6DNE6
names: Similarity
messages: Belongs to the pellino family.

8187:vip
gene id: 8187:vip
uniprot id: A0A4W6ETC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8187:LOC108887976
gene id: 8187:LOC108887976
uniprot id: A0A4W6EAC0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8187:kdsr
gene id: 8187:kdsr
uniprot id: A0A4W6DDY4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:prodh2
gene id: 8187:prodh2
uniprot id: A0A4W6G6L6
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

8187:sema4ba
gene id: 8187:sema4ba
uniprot id: A0A4W6CKE1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108886026
gene id: 8187:LOC108886026
uniprot id: A0A4W6GB44
names: Subcellular Location Annotation
messages: Membrane

8187:creg1
gene id: 8187:creg1
uniprot id: A0A4W6FUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

8187:cep20
gene id: 8187:cep20
uniprot id: A0A4W6C1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

8187:cstf3
gene id: 8187:cstf3
uniprot id: A0A4W6CGF9
names: Subcellular Location Annotation
messages: Nucleus

8187:eif3c
gene id: 8187:eif3c
uniprot id: A0A4W6G6K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8187:map4l
gene id: 8187:map4l
uniprot id: A0A4W6CX95
uniprot id: A0A4W6CXL1
names: Subcellular Location Annotation
messages: cytoskeleton

8187:LOC108888555
gene id: 8187:LOC108888555
uniprot id: A0A4W6EHZ9
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

8187:tsc22d2
gene id: 8187:tsc22d2
uniprot id: A0A4W6D8V6
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8187:tars1
gene id: 8187:tars1
uniprot id: A0A4W6EQM2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

8187:cmpk2
gene id: 8187:cmpk2
uniprot id: A0A4W6FHC2
names: Similarity
messages: Belongs to the thymidylate kinase family.

8187:rtn4a
gene id: 8187:rtn4a
uniprot id: A0A4W6BWD7
uniprot id: A0A4W6C3V5
uniprot id: A0A4W6C4G1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:hsd17b10
gene id: 8187:hsd17b10
uniprot id: A0A4W6FBM2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:LOC108895351
gene id: 8187:LOC108895351
uniprot id: A0A4W6FMR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8187:kmt5c
gene id: 8187:kmt5c
uniprot id: A0A4W6CA92
uniprot id: A0A4W6CIB3
names: Subcellular Location Annotation
messages: Nucleus

8187:tfb1m
gene id: 8187:tfb1m
uniprot id: A0A4W6DZV1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

8187:dkk3b
gene id: 8187:dkk3b
uniprot id: A0A4W6EEL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

8187:sfxn3
gene id: 8187:sfxn3
uniprot id: A0A4W6DRH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

8187:LOC108898145
gene id: 8187:LOC108898145
uniprot id: A0A4W6DWQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8187:dlx3b
gene id: 8187:dlx3b
uniprot id: A0A4W6DHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8187:fam83hb
gene id: 8187:fam83hb
uniprot id: A0A4W6DVL2
names: Similarity
messages: Belongs to the FAM83 family.

8187:antxr1d
gene id: 8187:antxr1d
uniprot id: A0A4W6C325
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8187:rab42a
gene id: 8187:rab42a
uniprot id: A0A4W6C0D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8187:ckap2l
gene id: 8187:ckap2l
uniprot id: A0A4W6FLG8
names: Similarity
messages: Belongs to the CKAP2 family.

8187:wdr76
gene id: 8187:wdr76
uniprot id: A0A4W6FQ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8187:relt
gene id: 8187:relt
uniprot id: A0A4W6BKT4
names: Similarity
messages: Belongs to the RELT family.

8187:si:dkey-13p1.4
gene id: 8187:si:dkey-13p1.4
uniprot id: A0A4W6FF77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8187:ewsr1b
gene id: 8187:ewsr1b
uniprot id: A0A4W6GBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

8187:zgc:112285
gene id: 8187:zgc:112285
uniprot id: A0A4W6DYJ7
names: Subcellular Location Annotation
messages: extracellular space

8187:gpib
gene id: 8187:gpib
uniprot id: A0A4W6E6J8
names: Similarity
messages: Belongs to the GPI family.

8187:e2f3
gene id: 8187:e2f3
uniprot id: A0A4W6FJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8187:LOC108899024
gene id: 8187:LOC108899024
uniprot id: A0A4W6FCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

8187:pou4f4
gene id: 8187:pou4f4
uniprot id: A0A4W6FAZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8187:maco1b
gene id: 8187:maco1b
uniprot id: A0A4W6DJQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8187:LOC108898646
gene id: 8187:LOC108898646
uniprot id: A0A4W6E3D1
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8187:soul4
gene id: 8187:soul4
uniprot id: A0A4W6DI94
names: Similarity
messages: Belongs to the HEBP family.

8187:LOC108877193
gene id: 8187:LOC108877193
uniprot id: A0A4W6FTK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
messages: extracellular space

8187:vasnb
gene id: 8187:vasnb
uniprot id: A0A4W6BQV2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:ube2al
gene id: 8187:ube2al
uniprot id: A0A4W6FHI4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:amigo1
gene id: 8187:amigo1
uniprot id: A0A4W6CEB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

8187:nme3
gene id: 8187:nme3
uniprot id: A0A4W6BSV3
uniprot id: A0A4W6BTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8187:vat1
gene id: 8187:vat1
uniprot id: A0A4W6FIR8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8187:washc5
gene id: 8187:washc5
uniprot id: A0A4W6EG74
names: Similarity
messages: Belongs to the strumpellin family.

8187:rpl27
gene id: 8187:rpl27
uniprot id: A0A4W6E1H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

8187:erbb2
gene id: 8187:erbb2
uniprot id: A0A4W6CEX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8187:s1pr5a
gene id: 8187:s1pr5a
uniprot id: A0A4W6F4L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:hdx
gene id: 8187:hdx
uniprot id: A0A4W6BTF2
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108890704
gene id: 8187:LOC108890704
uniprot id: A0A4W6FIW8
names: Subcellular Location Annotation
messages: Nucleus

8187:tipin
gene id: 8187:tipin
uniprot id: A0A4W6CDA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

8187:irf4a
gene id: 8187:irf4a
uniprot id: A0A4W6D635
names: Subcellular Location Annotation
messages: Nucleus

8187:lin9
gene id: 8187:lin9
uniprot id: A0A4W6D984
names: Similarity
messages: Belongs to the lin-9 family.

8187:plcb3
gene id: 8187:plcb3
uniprot id: A0A4W6EPR5
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

8187:LOC108873022
gene id: 8187:LOC108873022
uniprot id: A0A4W6F2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8187:LOC108872880
gene id: 8187:LOC108872880
uniprot id: A0A4W6BSU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108895473
gene id: 8187:LOC108895473
uniprot id: A0A4W6CWU5
names: Subcellular Location Annotation
messages: Membrane

8187:hikeshi
gene id: 8187:hikeshi
uniprot id: A0A4W6DFA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

8187:mmd2a
gene id: 8187:mmd2a
uniprot id: A0A4W6D840
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8187:slc4a2b
gene id: 8187:slc4a2b
uniprot id: A0A4W6G8P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

8187:c1qbp
gene id: 8187:c1qbp
uniprot id: A0A4W6EIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

8187:LOC108886135
gene id: 8187:LOC108886135
uniprot id: A0A4W6G8I7
names: Similarity
messages: Belongs to the peptidase C19 family.

8187:sfr1
gene id: 8187:sfr1
uniprot id: A0A4W6CSB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

8187:LOC108882046
gene id: 8187:LOC108882046
uniprot id: A0A4W6DA81
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

8187:tsfm
gene id: 8187:tsfm
uniprot id: A0A4W6EJ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

8187:serpinf2b
gene id: 8187:serpinf2b
uniprot id: A0A4W6BUX6
names: Similarity
messages: Belongs to the serpin family.

8187:grinaa
gene id: 8187:grinaa
uniprot id: A0A4W6DT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8187:LOC108885101
gene id: 8187:LOC108885101
uniprot id: A0A4W6BRX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8187:osbpl3b
gene id: 8187:osbpl3b
uniprot id: A0A4W6DKJ8
uniprot id: A0A4W6DKK1
names: Similarity
messages: Belongs to the OSBP family.

8187:zgc:113531
gene id: 8187:zgc:113531
uniprot id: A0A4W6BQK7
names: Subcellular Location Annotation
messages: Synapse

8187:sema4ab
gene id: 8187:sema4ab
uniprot id: A0A4W6FPG5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108902856
gene id: 8187:LOC108902856
uniprot id: A0A4W6DUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:camlg
gene id: 8187:camlg
uniprot id: A0A4W6DQ23
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

8187:hoxa11a
gene id: 8187:hoxa11a
uniprot id: A0A4W6EA09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8187:cd79a
gene id: 8187:cd79a
uniprot id: A0A4W6BNY0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108897194
gene id: 8187:LOC108897194
uniprot id: A0A4W6FCD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

8187:ints14
gene id: 8187:ints14
uniprot id: A0A4W6DI05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

8187:pcyt2
gene id: 8187:pcyt2
uniprot id: A0A4W6CD12
names: Similarity
messages: Belongs to the cytidylyltransferase family.

8187:roraa
gene id: 8187:roraa
uniprot id: A0A4W6DCK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:ap1m1
gene id: 8187:ap1m1
uniprot id: A0A4W6EFJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

8187:magoh
gene id: 8187:magoh
uniprot id: A0A4W6CTN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

8187:malsu1
gene id: 8187:malsu1
uniprot id: A0A4W6DJN7
names: Similarity
messages: Belongs to the Iojap/RsfS family.

8187:LOC108894333
gene id: 8187:LOC108894333
uniprot id: A0A4W6CWY7
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8187:LOC108903143
gene id: 8187:LOC108903143
uniprot id: A0A4W6BQC9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:LOC108882739
gene id: 8187:LOC108882739
uniprot id: A0A4W6BXZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:wdr35
gene id: 8187:wdr35
uniprot id: A0A4W6CHA3
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

8187:LOC108888167
gene id: 8187:LOC108888167
uniprot id: A0A4W6BIB3
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

8187:LOC108893043
gene id: 8187:LOC108893043
uniprot id: A0A4W6ED39
uniprot id: A0A4W6EFA9
uniprot id: A0A4W6EHX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

8187:ednrba
gene id: 8187:ednrba
uniprot id: A0A4W6CAH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:ostc
gene id: 8187:ostc
uniprot id: A0A4W6ECD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8187:LOC108896806
gene id: 8187:LOC108896806
uniprot id: A0A4W6EGU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8187:tacr1a
gene id: 8187:tacr1a
uniprot id: A0A4W6G738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:mfsd4ab
gene id: 8187:mfsd4ab
uniprot id: A0A4W6DM88
names: Subcellular Location Annotation
messages: Membrane

8187:six3a
gene id: 8187:six3a
uniprot id: A0A4W6F8H7
names: Subcellular Location Annotation
messages: Nucleus

8187:hmx2
gene id: 8187:hmx2
uniprot id: A0A4W6DLM5
names: Subcellular Location Annotation
messages: Nucleus

8187:mag
gene id: 8187:mag
uniprot id: A0A4W6BT64
names: Subcellular Location Annotation
messages: Membrane

8187:lsm14ab
gene id: 8187:lsm14ab
uniprot id: A0A4W6E787
names: Similarity
messages: Belongs to the LSM14 family.

8187:pacs2
gene id: 8187:pacs2
uniprot id: A0A4W6FIR2
names: Similarity
messages: Belongs to the PACS family.

8187:gpn2
gene id: 8187:gpn2
uniprot id: A0A4W6CJP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

8187:LOC108900130
gene id: 8187:LOC108900130
uniprot id: A0A4W6DE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8187:tmpob
gene id: 8187:tmpob
uniprot id: A0A4W6F6I1
names: Similarity
messages: Belongs to the LEM family.

8187:LOC108893384
gene id: 8187:LOC108893384
uniprot id: A0A4W6EKT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

8187:LOC108894339
gene id: 8187:LOC108894339
uniprot id: A0A4W6C633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8187:tomm20b
gene id: 8187:tomm20b
uniprot id: A0A4W6DIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

8187:si:ch211-210c8.6
gene id: 8187:si:ch211-210c8.6
uniprot id: A0A4W6FG96
names: Subcellular Location Annotation
messages: Membrane

8187:ampd1
gene id: 8187:ampd1
uniprot id: A0A4W6CFX9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

8187:sorcs3b
gene id: 8187:sorcs3b
uniprot id: A0A4W6D0I6
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

8187:rps15a
gene id: 8187:rps15a
uniprot id: A0A4W6C5D4
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

8187:exoc8
gene id: 8187:exoc8
uniprot id: A0A4W6ENQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

8187:brinp2
gene id: 8187:brinp2
uniprot id: A0A4W6BSL6
names: Similarity
messages: Belongs to the BRINP family.

8187:LOC108887761
gene id: 8187:LOC108887761
uniprot id: A0A4W6EIM4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

8187:LOC108892269
gene id: 8187:LOC108892269
uniprot id: A0A4W6DIG0
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

8187:si:ch211-215k15.4
gene id: 8187:si:ch211-215k15.4
uniprot id: A0A4W6CHM6
names: Function
names: Similarity
names: Subunit
messages: Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
messages: Belongs to the fucolectin family.
messages: Homotrimer.

8187:actl6a
gene id: 8187:actl6a
uniprot id: A0A4W6FGS9
names: Similarity
messages: Belongs to the actin family.

8187:LOC108898131
gene id: 8187:LOC108898131
uniprot id: A0A4W6E0D8
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8187:LOC108884215
gene id: 8187:LOC108884215
uniprot id: A0A4W6F5U0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:coro1ca
gene id: 8187:coro1ca
uniprot id: A0A4W6GAN4
names: Similarity
messages: Belongs to the WD repeat coronin family.

8187:mepcea
gene id: 8187:mepcea
uniprot id: A0A4W6CLE2
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8187:gas6
gene id: 8187:gas6
uniprot id: A0A4W6D8Z9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:gask1b
gene id: 8187:gask1b
uniprot id: A0A4W6FE95
names: Similarity
messages: Belongs to the GASK family.

8187:LOC108877935
gene id: 8187:LOC108877935
uniprot id: A0A4W6F6I0
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

8187:ptgr2
gene id: 8187:ptgr2
uniprot id: A0A4W6C191
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

8187:wscd2
gene id: 8187:wscd2
uniprot id: A0A4W6GAT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Golgi apparatus membrane
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

8187:LOC108886088
gene id: 8187:LOC108886088
uniprot id: A0A4W6C9M7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

8187:slc35e4
gene id: 8187:slc35e4
uniprot id: A0A4W6CE85
names: Subcellular Location Annotation
messages: Membrane

8187:slc25a43
gene id: 8187:slc25a43
uniprot id: A0A4W6EXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:tfap2e
gene id: 8187:tfap2e
uniprot id: A0A4W6F927
uniprot id: A0A4W6F9C8
names: Similarity
messages: Belongs to the AP-2 family.

8187:pth1r
gene id: 8187:pth1r
uniprot id: A0A4W6CEH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8187:ndufaf4
gene id: 8187:ndufaf4
uniprot id: A0A4W6DPA7
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

8187:LOC108881843
gene id: 8187:LOC108881843
uniprot id: A0A4W6FQ76
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108881244
gene id: 8187:LOC108881244
uniprot id: A0A4W6DDY2
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8187:pam16
gene id: 8187:pam16
uniprot id: A0A4W6BNP8
names: Similarity
messages: Belongs to the TIM16/PAM16 family.

8187:fev
gene id: 8187:fev
uniprot id: A0A4W6G8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:lin52
gene id: 8187:lin52
uniprot id: A0A4W6ETM8
names: Similarity
messages: Belongs to the lin-52 family.

8187:ccdc149a
gene id: 8187:ccdc149a
uniprot id: A0A4W6EF94
uniprot id: A0A4W6EGC9
names: Similarity
messages: Belongs to the CCDC149 family.

8187:cd74a
gene id: 8187:cd74a
uniprot id: A0A4W6C415
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:rbm8a
gene id: 8187:rbm8a
uniprot id: A0A4W6BVL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

8187:glb1
gene id: 8187:glb1
uniprot id: A0A4W6C0Y9
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

8187:LOC108902970
gene id: 8187:LOC108902970
uniprot id: A0A4W6BUS8
names: Similarity
messages: Belongs to the globin family.

8187:plod2
gene id: 8187:plod2
uniprot id: A0A4W6D9C8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8187:LOC108883316
gene id: 8187:LOC108883316
uniprot id: A0A4W6BLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

8187:serp2
gene id: 8187:serp2
uniprot id: A0A4W6FI60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

8187:LOC108873750
gene id: 8187:LOC108873750
uniprot id: A0A4W6C7X5
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

8187:cckbra
gene id: 8187:cckbra
uniprot id: A0A4W6E132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:gnsa
gene id: 8187:gnsa
uniprot id: A0A4W6D8P6
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8187:pi4kaa
gene id: 8187:pi4kaa
uniprot id: A0A4W6DHK9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8187:LOC108879032
gene id: 8187:LOC108879032
uniprot id: A0A4W6CYD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:ppp1r12c
gene id: 8187:ppp1r12c
uniprot id: A0A4W6DAF1
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

8187:LOC108888930
gene id: 8187:LOC108888930
uniprot id: A0A4W6D647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

8187:pgm2
gene id: 8187:pgm2
uniprot id: A0A4W6BR16
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8187:dis3l2
gene id: 8187:dis3l2
uniprot id: A0A4W6C2N7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

8187:ppp1r14ab
gene id: 8187:ppp1r14ab
uniprot id: A0A4W6BW44
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8187:LOC108898259
gene id: 8187:LOC108898259
uniprot id: A0A4W6G3R3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:LOC108900141
gene id: 8187:LOC108900141
uniprot id: A0A4W6DKR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

8187:adamts13
gene id: 8187:adamts13
uniprot id: A0A4W6FMQ8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:LOC108875858
gene id: 8187:LOC108875858
uniprot id: A8D3J6
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

8187:aff4
gene id: 8187:aff4
uniprot id: A0A4W6ELK7
uniprot id: A0A4W6EMK8
names: Similarity
messages: Belongs to the AF4 family.

8187:psmb10
gene id: 8187:psmb10
uniprot id: A0A4W6F858
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8187:id2a
gene id: 8187:id2a
uniprot id: A0A4W6FH86
names: Subcellular Location Annotation
messages: Nucleus

8187:slco3a1a
gene id: 8187:slco3a1a
uniprot id: A0A4W6CKG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8187:LOC108894766
gene id: 8187:LOC108894766
uniprot id: A0A4W6FGF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:ppp6r3
gene id: 8187:ppp6r3
uniprot id: A0A4W6BJB6
uniprot id: A0A4W6BQ02
names: Similarity
messages: Belongs to the SAPS family.

8187:snrnp200
gene id: 8187:snrnp200
uniprot id: A0A4W6G062
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

8187:sod2
gene id: 8187:sod2
uniprot id: A0A4W6EPN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

8187:nox1
gene id: 8187:nox1
uniprot id: A0A4W6E8I9
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108883389
gene id: 8187:LOC108883389
uniprot id: A0A4W6D138
names: Subcellular Location Annotation
messages: Membrane

8187:kiz
gene id: 8187:kiz
uniprot id: A0A4W6DXU0
uniprot id: A0A4W6DYS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

8187:hvcn1
gene id: 8187:hvcn1
uniprot id: A0A4W6E2Q9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

8187:drd1a
gene id: 8187:drd1a
uniprot id: A0A4W6CTZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:adam17b
gene id: 8187:adam17b
uniprot id: A0A4W6FZ75
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:bbs5
gene id: 8187:bbs5
uniprot id: A0A4W6FK72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

8187:ppp1r14bb
gene id: 8187:ppp1r14bb
uniprot id: A0A4W6EJ64
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8187:tmtc2b
gene id: 8187:tmtc2b
uniprot id: A0A4W6BYY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8187:LOC108893154
gene id: 8187:LOC108893154
uniprot id: A0A4W6EMX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8187:polh
gene id: 8187:polh
uniprot id: A0A4W6DGM7
names: Subcellular Location Annotation
messages: Nucleus

8187:KEG24 p10
gene id: 8187:KEG24_p10
uniprot id: Q3IA73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8187:hcst
gene id: 8187:hcst
uniprot id: A0A4W6CZK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAP10 family.
messages: Membrane

8187:gabrb4
gene id: 8187:gabrb4
uniprot id: A0A4W6F2T1
uniprot id: A0A4W6F520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:LOC108900728
gene id: 8187:LOC108900728
uniprot id: A0A4W6DST6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

8187:glis2b
gene id: 8187:glis2b
uniprot id: A0A4W6BK46
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8187:LOC108875899
gene id: 8187:LOC108875899
uniprot id: A0A4W6FTJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:cacnb1
gene id: 8187:cacnb1
uniprot id: A0A4W6FHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

8187:serf2b
gene id: 8187:serf2b
uniprot id: A0A4W6FJ70
names: Similarity
messages: Belongs to the SERF family.

8187:mindy4
gene id: 8187:mindy4
uniprot id: A0A4W6FI46
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

8187:snx30
gene id: 8187:snx30
uniprot id: A0A4W6BQ52
names: Similarity
messages: Belongs to the sorting nexin family.

8187:tlcd3a
gene id: 8187:tlcd3a
uniprot id: A0A4W6E5G7
names: Subcellular Location Annotation
messages: Membrane

8187:hoxc9a
gene id: 8187:hoxc9a
uniprot id: A0A4W6FKD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8187:sem1
gene id: 8187:sem1
uniprot id: A0A4W6EJ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

8187:b3gnt2b
gene id: 8187:b3gnt2b
uniprot id: A0A4W6DU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:sfmbt1
gene id: 8187:sfmbt1
uniprot id: A0A4W6FDT3
names: Subcellular Location Annotation
messages: Nucleus

8187:atp11b
gene id: 8187:atp11b
uniprot id: A0A4W6C3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8187:LOC108878019
gene id: 8187:LOC108878019
uniprot id: A0A4W6G4H9
names: Subcellular Location Annotation
messages: Secreted

8187:foxb2
gene id: 8187:foxb2
uniprot id: A0A4W6GAF3
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108887887
gene id: 8187:LOC108887887
uniprot id: A0A4W6E8C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8187:zgc:154058
gene id: 8187:zgc:154058
uniprot id: A0A4W6C5S5
names: Subcellular Location Annotation
messages: Membrane

8187:nipsnap2
gene id: 8187:nipsnap2
uniprot id: A0A4W6F9G5
names: Similarity
messages: Belongs to the NipSnap family.

8187:foxj1a
gene id: 8187:foxj1a
uniprot id: A0A4W6DEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FOXJ1 family.
messages: Nucleus

8187:hexa
gene id: 8187:hexa
uniprot id: A0A4W6DIZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

8187:LOC108891349
gene id: 8187:LOC108891349
uniprot id: A0A4W6FMN6
names: Similarity
messages: Belongs to the yippee family.

8187:bop1
gene id: 8187:bop1
uniprot id: A0A4W6DWK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

8187:mapk3
gene id: 8187:mapk3
uniprot id: A0A4W6BLN6
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8187:serinc2
gene id: 8187:serinc2
uniprot id: A0A4W6CGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8187:chmp4c
gene id: 8187:chmp4c
uniprot id: A0A4W6FJJ8
names: Similarity
messages: Belongs to the SNF7 family.

8187:ing1
gene id: 8187:ing1
uniprot id: A0A4W6FGI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8187:fam131c
gene id: 8187:fam131c
uniprot id: A0A4W6BPW6
names: Similarity
messages: Belongs to the FAM131 family.

8187:bcap31
gene id: 8187:bcap31
uniprot id: A0A4W6FZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

8187:mul1b
gene id: 8187:mul1b
uniprot id: A0A4W6FPJ7
names: Subcellular Location Annotation
messages: Membrane

8187:nrn1la
gene id: 8187:nrn1la
uniprot id: A0A4W6E0W5
names: Similarity
messages: Belongs to the neuritin family.

8187:LOC108883343
gene id: 8187:LOC108883343
uniprot id: A0A4W6CB99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

8187:gadd45gb.1
gene id: 8187:gadd45gb.1
uniprot id: A0A4W6E483
names: Similarity
messages: Belongs to the GADD45 family.

8187:LOC108873749
gene id: 8187:LOC108873749
uniprot id: A0A4W6CQ20
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8187:qtrt2
gene id: 8187:qtrt2
uniprot id: A0A4W6DKB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

8187:LOC108876997
gene id: 8187:LOC108876997
uniprot id: A0A4W6FUF7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:sppl2
gene id: 8187:sppl2
uniprot id: A0A4W6E8S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

8187:stoml3b
gene id: 8187:stoml3b
uniprot id: A0A4W6DCL6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8187:eif3s10
gene id: 8187:eif3s10
uniprot id: A0A4W6D111
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

8187:hm13
gene id: 8187:hm13
uniprot id: A0A4W6G586
uniprot id: A0A4W6G776
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

8187:tmem265
gene id: 8187:tmem265
uniprot id: A0A4W6EXJ1
names: Similarity
messages: Belongs to the TMEM121 family.

8187:LOC108884311
gene id: 8187:LOC108884311
uniprot id: A0A4W6BUM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8187:LOC108887772
gene id: 8187:LOC108887772
uniprot id: A0A4W6EK49
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:tbx21
gene id: 8187:tbx21
uniprot id: A0A4W6DWW6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8187:atp6ap1lb
gene id: 8187:atp6ap1lb
uniprot id: A0A4W6EZQ4
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

8187:mapk10
gene id: 8187:mapk10
uniprot id: A0A4W6CEH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8187:ctsba
gene id: 8187:ctsba
uniprot id: A0A4W6G0W8
names: Similarity
messages: Belongs to the peptidase C1 family.

8187:LOC108897748
gene id: 8187:LOC108897748
uniprot id: A0A4W6G2E0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

8187:ism2b
gene id: 8187:ism2b
uniprot id: A0A4W6DA87
names: Similarity
messages: Belongs to the isthmin family.

8187:shroom1
gene id: 8187:shroom1
uniprot id: A0A4W6EMG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

8187:LOC108886598
gene id: 8187:LOC108886598
uniprot id: A0A4W6F160
names: Similarity
messages: Belongs to the FAM124 family.

8187:ramp2
gene id: 8187:ramp2
uniprot id: A0A4W6CQR0
uniprot id: A0A4W6CR63
names: Similarity
messages: Belongs to the RAMP family.

8187:nhej1
gene id: 8187:nhej1
uniprot id: A0A4W6EX39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

8187:yipf5
gene id: 8187:yipf5
uniprot id: A0A4W6EX09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

8187:kcng1
gene id: 8187:kcng1
uniprot id: A0A4W6FXW0
names: Subcellular Location Annotation
messages: Membrane

8187:psme4a
gene id: 8187:psme4a
uniprot id: A0A4W6E6P5
uniprot id: A0A4W6EAJ6
names: Similarity
messages: Belongs to the BLM10 family.

8187:LOC108885630
gene id: 8187:LOC108885630
uniprot id: A0A4W6F7T5
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8187:oafa
gene id: 8187:oafa
uniprot id: A0A4W6D0Q1
names: Similarity
messages: Belongs to the OAF family.

8187:LOC108895887
gene id: 8187:LOC108895887
uniprot id: A0A4W6FLA6
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

8187:tdrd3
gene id: 8187:tdrd3
uniprot id: A0A4W6D1N0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.

8187:LOC108876903
gene id: 8187:LOC108876903
uniprot id: A0A4W6E8C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8187:LOC108874380
gene id: 8187:LOC108874380
uniprot id: A0A4W6C4U2
names: Similarity
messages: Belongs to the PA28 family.

8187:sass6
gene id: 8187:sass6
uniprot id: A0A4W6BWJ6
names: Subcellular Location Annotation
messages: centrosome

8187:slc16a1a
gene id: 8187:slc16a1a
uniprot id: A0A4W6CIV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8187:cntn3b
gene id: 8187:cntn3b
uniprot id: A0A4W6FWG5
names: Subcellular Location Annotation
messages: Membrane

8187:stx2b
gene id: 8187:stx2b
uniprot id: A0A4W6FKD7
uniprot id: A0A4W6FM64
names: Similarity
messages: Belongs to the syntaxin family.

8187:mon1a
gene id: 8187:mon1a
uniprot id: A0A4W6EQ11
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

8187:p4hb
gene id: 8187:p4hb
uniprot id: A0A4W6DAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8187:LOC108881410
gene id: 8187:LOC108881410
uniprot id: A0A4W6BSZ0
names: Similarity
messages: Belongs to the NAC-beta family.

8187:KEG24 p03
gene id: 8187:KEG24_p03
uniprot id: Q3IA66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8187:tubb2b
gene id: 8187:tubb2b
uniprot id: A0A4W6G6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8187:LOC108888630
gene id: 8187:LOC108888630
uniprot id: A0A4W6E331
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

8187:smad7
gene id: 8187:smad7
uniprot id: A0A4W6CB21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108887929
gene id: 8187:LOC108887929
uniprot id: A0A4W6C8Z8
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108883894
gene id: 8187:LOC108883894
uniprot id: A0A4W6CAQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108885442
gene id: 8187:LOC108885442
uniprot id: A0A4W6E084
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:LOC108874025
gene id: 8187:LOC108874025
uniprot id: A0A4W6C854
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

8187:ndrg2
gene id: 8187:ndrg2
uniprot id: A0A4W6EJX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.
messages: Cytoplasm

8187:tprg1
gene id: 8187:tprg1
uniprot id: A0A4W6DLV9
names: Similarity
messages: Belongs to the TPRG1 family.

8187:adcyap1b
gene id: 8187:adcyap1b
uniprot id: A0A4W6F189
uniprot id: A0A4W6F3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8187:LOC108894784
gene id: 8187:LOC108894784
uniprot id: A0A4W6FUB3
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

8187:igfbp2a
gene id: 8187:igfbp2a
uniprot id: A0A4W6F4R7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:LOC108896194
gene id: 8187:LOC108896194
uniprot id: A0A4W6CDX4
names: Similarity
messages: Belongs to the arrestin family.

8187:slc25a44a
gene id: 8187:slc25a44a
uniprot id: A0A4W6CF18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:akr1a1a
gene id: 8187:akr1a1a
uniprot id: A0A4W6GC35
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8187:senp1
gene id: 8187:senp1
uniprot id: A0A4W6FLI4
names: Similarity
messages: Belongs to the peptidase C48 family.

8187:LOC108884431
gene id: 8187:LOC108884431
uniprot id: A0A4W6G4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

8187:p3h1
gene id: 8187:p3h1
uniprot id: A0A4W6FK00
names: Similarity
messages: Belongs to the leprecan family.

8187:b3gnt2l
gene id: 8187:b3gnt2l
uniprot id: A0A4W6CKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108884025
gene id: 8187:LOC108884025
uniprot id: A0A4W6CCT8
names: Similarity
messages: Belongs to the MAP7 family.

8187:LOC108882867
gene id: 8187:LOC108882867
uniprot id: A0A4W6DFY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8187:mpi
gene id: 8187:mpi
uniprot id: A0A4W6C621
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

8187:srp9
gene id: 8187:srp9
uniprot id: A0A4W6DMV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

8187:LOC108900280
gene id: 8187:LOC108900280
uniprot id: A0A4W6BYI1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:bcap29
gene id: 8187:bcap29
uniprot id: A0A4W6D2F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

8187:LOC108887773
gene id: 8187:LOC108887773
uniprot id: A0A4W6EFQ5
names: Subcellular Location Annotation
messages: Membrane

8187:hhatlb
gene id: 8187:hhatlb
uniprot id: A0A4W6DDA5
names: Subcellular Location Annotation
messages: Membrane

8187:praf2
gene id: 8187:praf2
uniprot id: A0A4W6C7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8187:rhbdd1
gene id: 8187:rhbdd1
uniprot id: A0A4W6CX24
names: Subcellular Location Annotation
messages: Membrane

8187:negr1
gene id: 8187:negr1
uniprot id: A0A4W6DTV4
uniprot id: A0A4W6DU55
names: Subcellular Location Annotation
messages: Membrane

8187:zic4
gene id: 8187:zic4
uniprot id: A0A4W6D902
uniprot id: A0A4W6D9A8
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8187:dhrs7b
gene id: 8187:dhrs7b
uniprot id: A0A4W6BKF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:LOC108873447
gene id: 8187:LOC108873447
uniprot id: A0A4W6E0Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8187:LOC108878236
gene id: 8187:LOC108878236
uniprot id: A0A4W6FUN1
names: Similarity
messages: Belongs to the serpin family.

8187:twsg1a
gene id: 8187:twsg1a
uniprot id: A0A4W6FQF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

8187:zgc:123258
gene id: 8187:zgc:123258
uniprot id: A0A4W6FKB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

8187:LOC108878083
gene id: 8187:LOC108878083
uniprot id: A0A4W6GAD3
uniprot id: A0A4W6GB58
uniprot id: A0A4W6GBQ7
names: Subcellular Location Annotation
messages: Cytoplasm

8187:acads
gene id: 8187:acads
uniprot id: A0A4W6F974
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8187:b3gnt5a
gene id: 8187:b3gnt5a
uniprot id: A0A4W6FXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:tbcd
gene id: 8187:tbcd
uniprot id: A0A4W6FZJ6
names: Similarity
messages: Belongs to the TBCD family.

8187:alp3
gene id: 8187:alp3
uniprot id: A0A4W6C078
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

8187:hspa8
gene id: 8187:hspa8
uniprot id: A0A4W6DU61
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8187:smad3a
gene id: 8187:smad3a
uniprot id: A0A4W6BUQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108899775
gene id: 8187:LOC108899775
uniprot id: A0A4W6FMZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

8187:LOC108895168
gene id: 8187:LOC108895168
uniprot id: A0A4W6BVN0
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108884546
gene id: 8187:LOC108884546
uniprot id: A0A4W6DAH0
names: Similarity
messages: Belongs to the Rho GDI family.

8187:tmem115
gene id: 8187:tmem115
uniprot id: A0A4W6G8Y2
names: Subcellular Location Annotation
messages: Membrane

8187:katnal2
gene id: 8187:katnal2
uniprot id: A0A4W6C8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

8187:LOC108889537
gene id: 8187:LOC108889537
uniprot id: A0A4W6E362
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

8187:ptpn1
gene id: 8187:ptpn1
uniprot id: A0A4W6E9G2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8187:LOC108875185
gene id: 8187:LOC108875185
uniprot id: A0A4W6DDN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8187:kcnj5
gene id: 8187:kcnj5
uniprot id: A0A4W6CVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8187:atg101
gene id: 8187:atg101
uniprot id: A0A4W6E849
names: Similarity
messages: Belongs to the ATG101 family.

8187:mrps30
gene id: 8187:mrps30
uniprot id: A0A4W6EIC9
names: Subcellular Location Annotation
messages: Mitochondrion

8187:LOC108874910
gene id: 8187:LOC108874910
uniprot id: A0A4W6F6I5
names: Subcellular Location Annotation
messages: Cytoplasm

8187:gpia
gene id: 8187:gpia
uniprot id: A0A4W6G1F7
names: Similarity
messages: Belongs to the GPI family.

8187:LOC108890410
gene id: 8187:LOC108890410
uniprot id: A0A4W6CX53
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

8187:camk2n1a
gene id: 8187:camk2n1a
uniprot id: A0A4W6E4Z5
names: Similarity
messages: Belongs to the CAMK2N family.

8187:glipr1a
gene id: 8187:glipr1a
uniprot id: A0A4W6E417
names: Similarity
messages: Belongs to the CRISP family.

8187:igf1ra
gene id: 8187:igf1ra
uniprot id: A0A4W6D4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

8187:LOC108876264
gene id: 8187:LOC108876264
uniprot id: A0A4W6EUM8
uniprot id: A0A4W6EXZ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108874469
gene id: 8187:LOC108874469
uniprot id: A0A4W6CW27
names: Subcellular Location Annotation
messages: Nucleus

8187:cad
gene id: 8187:cad
uniprot id: A0A4W6DEP5
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

8187:ism1
gene id: 8187:ism1
uniprot id: A0A4W6BWR5
names: Similarity
messages: Belongs to the isthmin family.

8187:usp2a
gene id: 8187:usp2a
uniprot id: A0A4W6BII1
uniprot id: A0A4W6BQD6
names: Similarity
messages: Belongs to the peptidase C19 family.

8187:nkiras1
gene id: 8187:nkiras1
uniprot id: A0A4W6BXY4
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

8187:islr2
gene id: 8187:islr2
uniprot id: A0A4W6DH80
names: Subcellular Location Annotation
messages: Membrane

8187:plpp4
gene id: 8187:plpp4
uniprot id: A0A4W6FDP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8187:napgb
gene id: 8187:napgb
uniprot id: A0A4W6FQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane

8187:ppic
gene id: 8187:ppic
uniprot id: A0A4W6G3Z7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8187:LOC108888223
gene id: 8187:LOC108888223
uniprot id: A0A4W6CAX0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:ttyh3b
gene id: 8187:ttyh3b
uniprot id: A0A4W6FGE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8187:LOC108880847
gene id: 8187:LOC108880847
uniprot id: A0A4W6EKM6
names: Subcellular Location Annotation
messages: Nucleus

8187:cpeb1b
gene id: 8187:cpeb1b
uniprot id: A0A4W6EPE9
names: Similarity
messages: Belongs to the RRM CPEB family.

8187:hmbox1b
gene id: 8187:hmbox1b
uniprot id: A0A4W6CLJ8
names: Subcellular Location Annotation
messages: Nucleus

8187:rnf20
gene id: 8187:rnf20
uniprot id: A0A4W6C0K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

8187:tm4sf21a
gene id: 8187:tm4sf21a
uniprot id: A0A4W6BMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8187:onecut1
gene id: 8187:onecut1
uniprot id: A0A4W6F0A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8187:LOC108893952
gene id: 8187:LOC108893952
uniprot id: A0A4W6E2V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8187:LOC108893105
gene id: 8187:LOC108893105
uniprot id: A0A4W6EZQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

8187:fscn1a
gene id: 8187:fscn1a
uniprot id: A0A4W6DC04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8187:gpn3
gene id: 8187:gpn3
uniprot id: A0A4W6DDI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

8187:irf4l
gene id: 8187:irf4l
uniprot id: A0A4W6F7Z3
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108901354
gene id: 8187:LOC108901354
uniprot id: A0A4W6D1F7
names: Subcellular Location Annotation
messages: Membrane

8187:lg23h8orf33
gene id: 8187:lg23h8orf33
uniprot id: A0A4W6G142
names: Similarity
messages: Belongs to the UPF0488 family.

8187:inha
gene id: 8187:inha
uniprot id: A0A4W6F2X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

8187:pik3r3b
gene id: 8187:pik3r3b
uniprot id: A0A4W6E954
uniprot id: A0A4W6EA84
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

8187:tada3l
gene id: 8187:tada3l
uniprot id: A0A4W6F5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

8187:LOC108885582
gene id: 8187:LOC108885582
uniprot id: A0A4W6ET83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8187:epdr1
gene id: 8187:epdr1
uniprot id: A0A4W6BMF7
names: Similarity
messages: Belongs to the ependymin family.

8187:nfil3-2
gene id: 8187:nfil3-2
uniprot id: A0A4W6ECL1
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8187:ano5a
gene id: 8187:ano5a
uniprot id: A0A4W6DBB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:lg17h19orf25
gene id: 8187:lg17h19orf25
uniprot id: A0A4W6DQV7
names: Similarity
messages: Belongs to the UPF0449 family.

8187:camsap2b
gene id: 8187:camsap2b
uniprot id: A0A4W6E9H5
uniprot id: A0A4W6E9S9
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8187:nxpe3
gene id: 8187:nxpe3
uniprot id: A0A4W6FKB8
names: Similarity
messages: Belongs to the NXPE family.

8187:LOC108887953
gene id: 8187:LOC108887953
uniprot id: A0A4W6CGH2
uniprot id: A0A4W6CK42
uniprot id: A0A4W6CKN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8187:LOC108890802
gene id: 8187:LOC108890802
uniprot id: A0A4W6BIW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

8187:uts2r4
gene id: 8187:uts2r4
uniprot id: A0A4W6CUM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

8187:LOC108902281
gene id: 8187:LOC108902281
uniprot id: A0A4W6CNE4
names: Similarity
messages: Belongs to the peptidase C19 family.

8187:scarb2c
gene id: 8187:scarb2c
uniprot id: A0A4W6C336
names: Similarity
messages: Belongs to the CD36 family.

8187:LOC108876311
gene id: 8187:LOC108876311
uniprot id: A0A4W6EGW4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:LOC108873841
gene id: 8187:LOC108873841
uniprot id: A0A4W6F200
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8187:LOC108879924
gene id: 8187:LOC108879924
uniprot id: A0A4W6FSW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

8187:ssh1a
gene id: 8187:ssh1a
uniprot id: A0A4W6GB25
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

8187:tmem192
gene id: 8187:tmem192
uniprot id: A0A4W6EJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

8187:LOC108878839
gene id: 8187:LOC108878839
uniprot id: A0A4W6CTE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8187:phospho2
gene id: 8187:phospho2
uniprot id: A0A4W6FYQ7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

8187:kifc1
gene id: 8187:kifc1
uniprot id: A0A4W6F4D6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8187:kcnk1b
gene id: 8187:kcnk1b
uniprot id: A0A4W6EFH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

8187:wee1
gene id: 8187:wee1
uniprot id: A0A4W6C4I2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

8187:acmsd
gene id: 8187:acmsd
uniprot id: A0A4W6GBS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

8187:phox2bb
gene id: 8187:phox2bb
uniprot id: A0A4W6FYZ1
names: Subcellular Location Annotation
messages: Nucleus

8187:rrm2b
gene id: 8187:rrm2b
uniprot id: A0A4W6DYL0
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

8187:chrdl2
gene id: 8187:chrdl2
uniprot id: A0A4W6CLL4
names: Subcellular Location Annotation
messages: Secreted

8187:gatc
gene id: 8187:gatc
uniprot id: A0A4W6GB12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8187:rnaseka
gene id: 8187:rnaseka
uniprot id: A0A4W6DIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

8187:LOC108884253
gene id: 8187:LOC108884253
uniprot id: A0A4W6FSJ2
names: Similarity
messages: Belongs to the TMEM14 family.

8187:LOC108883136
gene id: 8187:LOC108883136
uniprot id: A0A4W6E5D9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8187:LOC108884650
gene id: 8187:LOC108884650
uniprot id: A0A4W6DVF2
names: Function
names: Similarity
messages: Belongs to the Nudix hydrolase family.
messages: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.

8187:atosa
gene id: 8187:atosa
uniprot id: A0A4W6EZL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

8187:LOC108878938
gene id: 8187:LOC108878938
uniprot id: A0A4W6CZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

8187:chfr
gene id: 8187:chfr
uniprot id: A0A4W6EQN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

8187:mipa
gene id: 8187:mipa
uniprot id: A0A4W6EM14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8187:il17ra1a
gene id: 8187:il17ra1a
uniprot id: A0A4W6DQZ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108902974
gene id: 8187:LOC108902974
uniprot id: A0A4W6BZT0
names: Similarity
messages: Belongs to the globin family.

8187:mtmr4
gene id: 8187:mtmr4
uniprot id: A0A4W6ENI4
uniprot id: A0A4W6ERG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

8187:LOC108878663
gene id: 8187:LOC108878663
uniprot id: A0A4W6G925
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

8187:LOC108892882
gene id: 8187:LOC108892882
uniprot id: A0A4W6F1Z2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:ccnjl
gene id: 8187:ccnjl
uniprot id: A0A4W6E7M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:LOC108895781
gene id: 8187:LOC108895781
uniprot id: A0A4W6CMH5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:LOC108897280
gene id: 8187:LOC108897280
uniprot id: A0A4W6D719
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

8187:rps21
gene id: 8187:rps21
uniprot id: A0A4W6G1Q1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

8187:slc6a1b
gene id: 8187:slc6a1b
uniprot id: A0A4W6EZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8187:sptlc3
gene id: 8187:sptlc3
uniprot id: A0A4W6BX29
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8187:LOC108901383
gene id: 8187:LOC108901383
uniprot id: A0A4W6D3M7
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8187:im:7151449
gene id: 8187:im:7151449
uniprot id: A0A4W6D5A5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:hdac7a
gene id: 8187:hdac7a
uniprot id: A0A4W6CX67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8187:waslb
gene id: 8187:waslb
uniprot id: A0A4W6BQS7
uniprot id: A0A4W6BRH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: cytoskeleton

8187:ptx3a
gene id: 8187:ptx3a
uniprot id: A0A4W6E8H1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:kcnh8
gene id: 8187:kcnh8
uniprot id: A0A4W6EE92
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8187:spcs1
gene id: 8187:spcs1
uniprot id: A0A4W6DJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108892576
gene id: 8187:LOC108892576
uniprot id: A0A4W6EUM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

8187:cdc34a
gene id: 8187:cdc34a
uniprot id: A0A4W6G420
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:ypel3
gene id: 8187:ypel3
uniprot id: A0A4W6BLS3
names: Similarity
messages: Belongs to the yippee family.

8187:baz2ba
gene id: 8187:baz2ba
uniprot id: A0A4W6CYQ4
uniprot id: A0A4W6CYU2
uniprot id: A0A4W6CZI9
names: Similarity
messages: Belongs to the WAL family.

8187:LOC108887801
gene id: 8187:LOC108887801
uniprot id: A0A4W6EPU7
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108882305
gene id: 8187:LOC108882305
uniprot id: A0A4W6E5J5
names: Similarity
messages: Belongs to the TMEM121 family.

8187:zgc:153704
gene id: 8187:zgc:153704
uniprot id: A0A4W6CSQ4
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8187:pdk3a
gene id: 8187:pdk3a
uniprot id: A0A4W6CKG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8187:nr2c2
gene id: 8187:nr2c2
uniprot id: A0A4W6D8D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:slc20a1a
gene id: 8187:slc20a1a
uniprot id: A0A4W6FNT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

8187:zgc:86609
gene id: 8187:zgc:86609
uniprot id: A0A4W6D951
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

8187:actb2
gene id: 8187:actb2
uniprot id: A0A4W6DCW0
names: Similarity
messages: Belongs to the actin family.

8187:dmrt3a
gene id: 8187:dmrt3a
uniprot id: A0A4W6FH65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8187:cpn1
gene id: 8187:cpn1
uniprot id: A0A4W6CBM6
names: Similarity
messages: Belongs to the peptidase M14 family.

8187:fut11
gene id: 8187:fut11
uniprot id: A0A4W6DSP6
uniprot id: A0A4W6DUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

8187:parvaa
gene id: 8187:parvaa
uniprot id: A0A4W6EGF4
names: Similarity
messages: Belongs to the parvin family.

8187:bgnb
gene id: 8187:bgnb
uniprot id: A0A4W6F0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

8187:fmr1
gene id: 8187:fmr1
uniprot id: A0A4W6FUQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Stress granule
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

8187:aldh6a1
gene id: 8187:aldh6a1
uniprot id: A0A4W6F340
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

8187:LOC108900060
gene id: 8187:LOC108900060
uniprot id: A0A4W6DKS7
names: Subcellular Location Annotation
messages: Membrane

8187:nek8
gene id: 8187:nek8
uniprot id: A0A4W6DMZ4
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

8187:guk1a
gene id: 8187:guk1a
uniprot id: A0A4W6C632
names: Similarity
messages: Belongs to the guanylate kinase family.

8187:LOC108900293
gene id: 8187:LOC108900293
uniprot id: A0A4W6C8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

8187:ndufs4
gene id: 8187:ndufs4
uniprot id: A0A4W6BKP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

8187:tlcd5a
gene id: 8187:tlcd5a
uniprot id: A0A4W6D013
names: Subcellular Location Annotation
messages: Membrane

8187:ugp2b
gene id: 8187:ugp2b
uniprot id: A0A4W6DSI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

8187:slc25a25b
gene id: 8187:slc25a25b
uniprot id: A0A4W6DQL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8187:il6st
gene id: 8187:il6st
uniprot id: A0A4W6FE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

8187:LOC108891645
gene id: 8187:LOC108891645
uniprot id: A0A4W6G7E4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108889552
gene id: 8187:LOC108889552
uniprot id: A0A4W6C6M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8187:rsad1
gene id: 8187:rsad1
uniprot id: A0A4W6FZ84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

8187:LOC108875028
gene id: 8187:LOC108875028
uniprot id: A0A4W6F1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

8187:LOC108896242
gene id: 8187:LOC108896242
uniprot id: A0A4W6F8V4
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

8187:LOC108891529
gene id: 8187:LOC108891529
uniprot id: A0A4W6E842
names: Subcellular Location Annotation
messages: Membrane

8187:spns1
gene id: 8187:spns1
uniprot id: A0A4W6D571
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

8187:LOC108893556
gene id: 8187:LOC108893556
uniprot id: A0A4W6D7D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:trarg1a
gene id: 8187:trarg1a
uniprot id: A0A4W6DPF1
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8187:yipf4
gene id: 8187:yipf4
uniprot id: A0A4W6E6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108896011
gene id: 8187:LOC108896011
uniprot id: A0A4W6F8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8187:atl3
gene id: 8187:atl3
uniprot id: A0A4W6EXV2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8187:lrrc4.1
gene id: 8187:lrrc4.1
uniprot id: A0A4W6CL89
names: Subcellular Location Annotation
messages: Membrane

8187:evx2
gene id: 8187:evx2
uniprot id: A0A4W6EAA2
names: Subcellular Location Annotation
messages: Nucleus

8187:actmap
gene id: 8187:actmap
uniprot id: A0A4W6CPH2
names: Similarity
messages: Belongs to the ACTMAP family.

8187:ube2d2
gene id: 8187:ube2d2
uniprot id: A0A4W6FR09
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:si:ch211-216b21.2
gene id: 8187:si:ch211-216b21.2
uniprot id: A0A4W6DZ98
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:mpeg1.1
gene id: 8187:mpeg1.1
uniprot id: A0A4W6BSC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

8187:miga2
gene id: 8187:miga2
uniprot id: A0A4W6BP44
names: Similarity
messages: Belongs to the mitoguardin family.

8187:rpa3
gene id: 8187:rpa3
uniprot id: A0A4W6CIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

8187:acox1
gene id: 8187:acox1
uniprot id: A0A4W6F0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

8187:gbx1
gene id: 8187:gbx1
uniprot id: A0A4W6CHC8
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108900334
gene id: 8187:LOC108900334
uniprot id: A0A4W6CI39
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8187:LOC108872888
gene id: 8187:LOC108872888
uniprot id: A0A4W6BYR8
names: Similarity
messages: Belongs to the COX20 family.

8187:cd68
gene id: 8187:cd68
uniprot id: A0A4W6FB89
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

8187:zic2a
gene id: 8187:zic2a
uniprot id: A0A4W6DE05
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8187:pigm
gene id: 8187:pigm
uniprot id: A0A4W6FZC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

8187:LOC108883697
gene id: 8187:LOC108883697
uniprot id: A0A4W6FBT5
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

8187:LOC108881385
gene id: 8187:LOC108881385
uniprot id: A0A4W6G3D1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108899369
gene id: 8187:LOC108899369
uniprot id: A0A4W6CQX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

8187:ubald2
gene id: 8187:ubald2
uniprot id: A0A4W6DEL4
names: Similarity
messages: Belongs to the UBALD family.

8187:LOC108892841
gene id: 8187:LOC108892841
uniprot id: A0A4W6F726
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

8187:ptgdsb.1
gene id: 8187:ptgdsb.1
uniprot id: A0A4W6FQI5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8187:LOC108886350
gene id: 8187:LOC108886350
uniprot id: A0A4W6E8E8
names: Subcellular Location Annotation
messages: Membrane

8187:proca1
gene id: 8187:proca1
uniprot id: A0A4W6DLD0
names: Subcellular Location Annotation
messages: Secreted

8187:abcg2d
gene id: 8187:abcg2d
uniprot id: A0A4W6BYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8187:mapkapk2a
gene id: 8187:mapkapk2a
uniprot id: A0A4W6DMF8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:cercam
gene id: 8187:cercam
uniprot id: A0A4W6C2X5
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8187:s1pr2
gene id: 8187:s1pr2
uniprot id: A0A4W6FYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:galnt7
gene id: 8187:galnt7
uniprot id: A0A4W6FA71
uniprot id: A0A4W6FAD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8187:ing2
gene id: 8187:ing2
uniprot id: A0A4W6FA67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8187:LOC108893945
gene id: 8187:LOC108893945
uniprot id: A0A4W6DAX5
names: Subcellular Location Annotation
messages: Membrane

8187:stk17a
gene id: 8187:stk17a
uniprot id: A0A4W6BL44
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108878680
gene id: 8187:LOC108878680
uniprot id: A0A4W6FVK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8187:pex7
gene id: 8187:pex7
uniprot id: A0A4W6EK11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

8187:trpc1
gene id: 8187:trpc1
uniprot id: A0A4W6D440
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

8187:tsg101a
gene id: 8187:tsg101a
uniprot id: A0A4W6EHM1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

8187:mettl15
gene id: 8187:mettl15
uniprot id: A0A4W6EX12
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

8187:dbx2
gene id: 8187:dbx2
uniprot id: A0A4W6FMU4
names: Subcellular Location Annotation
messages: Nucleus

8187:pde9ac
gene id: 8187:pde9ac
uniprot id: A0A4W6D024
uniprot id: A0A4W6D029
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8187:LOC108900792
gene id: 8187:LOC108900792
uniprot id: A0A4W6DFF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8187:si:ch211-127i16.2
gene id: 8187:si:ch211-127i16.2
uniprot id: A0A4W6C0G9
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8187:LOC108894246
gene id: 8187:LOC108894246
uniprot id: A0A4W6CD40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:stx19
gene id: 8187:stx19
uniprot id: A0A4W6FFD7
names: Similarity
messages: Belongs to the syntaxin family.

8187:ankrd34ba
gene id: 8187:ankrd34ba
uniprot id: A0A4W6DHI6
names: Similarity
messages: Belongs to the ANKRD34 family.

8187:LOC108878368
gene id: 8187:LOC108878368
uniprot id: A0A4W6DIL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:sema6dl
gene id: 8187:sema6dl
uniprot id: A0A4W6C763
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:mipb
gene id: 8187:mipb
uniprot id: A0A4W6EU22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8187:LOC108876134
gene id: 8187:LOC108876134
uniprot id: A0A4W6CQV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

8187:zgc:112271
gene id: 8187:zgc:112271
uniprot id: A0A4W6F828
names: Similarity
messages: Belongs to the BolA/IbaG family.

8187:tmem244
gene id: 8187:tmem244
uniprot id: A0A4W6EUB8
names: Subcellular Location Annotation
messages: Membrane

8187:man2b2
gene id: 8187:man2b2
uniprot id: A0A4W6CRN2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

8187:anxa1a
gene id: 8187:anxa1a
uniprot id: A0A4W6FX60
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8187:thbs4a
gene id: 8187:thbs4a
uniprot id: A0A4W6G961
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:cfi
gene id: 8187:cfi
uniprot id: A0A4W6DI18
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8187:ppil4
gene id: 8187:ppil4
uniprot id: A0A4W6C0D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8187:tmem97
gene id: 8187:tmem97
uniprot id: A0A4W6CH16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8187:LOC108890919
gene id: 8187:LOC108890919
uniprot id: A0A4W6FFN9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8187:cebpb
gene id: 8187:cebpb
uniprot id: A0A4W6EDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

8187:bcor
gene id: 8187:bcor
uniprot id: A0A4W6DAI2
names: Similarity
messages: Belongs to the BCOR family.

8187:LOC108880420
gene id: 8187:LOC108880420
uniprot id: A0A4W6EY10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8187:igsf9b
gene id: 8187:igsf9b
uniprot id: A0A4W6G0D5
uniprot id: A0A4W6G0D7
names: Subcellular Location Annotation
messages: Membrane

8187:ido1
gene id: 8187:ido1
uniprot id: A0A4W6G7Z4
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

8187:gpatch11
gene id: 8187:gpatch11
uniprot id: A0A4W6CDP9
names: Similarity
messages: Belongs to the GPATCH11 family.

8187:hoxb2a
gene id: 8187:hoxb2a
uniprot id: A0A4W6C7Q2
names: Subcellular Location Annotation
messages: Nucleus

8187:steep1
gene id: 8187:steep1
uniprot id: A0A4W6DD85
names: Similarity
messages: Belongs to the STEEP1 family.

8187:atf7ip
gene id: 8187:atf7ip
uniprot id: A0A4W6FXY4
uniprot id: A0A4W6FY14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

8187:cand1
gene id: 8187:cand1
uniprot id: A0A4W6CZ84
names: Similarity
messages: Belongs to the CAND family.

8187:gnav1
gene id: 8187:gnav1
uniprot id: A0A4W6CBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

8187:stxbp5l
gene id: 8187:stxbp5l
uniprot id: A0A4W6DEA9
uniprot id: A0A4W6DEC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8187:arsb
gene id: 8187:arsb
uniprot id: A0A4W6CYY0
names: Similarity
messages: Belongs to the sulfatase family.

8187:pdhb
gene id: 8187:pdhb
uniprot id: A0A4W6BSR7
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

8187:LOC108884436
gene id: 8187:LOC108884436
uniprot id: A0A4W6G4X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

8187:prpf18
gene id: 8187:prpf18
uniprot id: A0A4W6DRU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

8187:lgi2a
gene id: 8187:lgi2a
uniprot id: A0A4W6EGT2
names: Subcellular Location Annotation
messages: Secreted

8187:LOC108881353
gene id: 8187:LOC108881353
uniprot id: A0A4W6FUK4
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8187:fas
gene id: 8187:fas
uniprot id: A0A4W6CRW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:foxn2a
gene id: 8187:foxn2a
uniprot id: A0A4W6EY74
names: Subcellular Location Annotation
messages: Nucleus

8187:zgc:158689
gene id: 8187:zgc:158689
uniprot id: A0A4W6FF54
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

8187:cdk10
gene id: 8187:cdk10
uniprot id: A0A4W6EP53
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:irx4b
gene id: 8187:irx4b
uniprot id: A0A4W6FJW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8187:timm13
gene id: 8187:timm13
uniprot id: A0A4W6FLW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8187:LOC108888818
gene id: 8187:LOC108888818
uniprot id: A0A4W6DM56
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:LOC108902118
gene id: 8187:LOC108902118
uniprot id: A0A4W6ECF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:cnot10
gene id: 8187:cnot10
uniprot id: A0A4W6CDB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

8187:smpd1
gene id: 8187:smpd1
uniprot id: A0A4W6DCI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

8187:b3gnt5b
gene id: 8187:b3gnt5b
uniprot id: A0A4W6FNN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:cntn3a.1
gene id: 8187:cntn3a.1
uniprot id: A0A4W6C7M3
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108887393
gene id: 8187:LOC108887393
uniprot id: A0A4W6G2R2
names: Subcellular Location Annotation
messages: Membrane

8187:sgsh
gene id: 8187:sgsh
uniprot id: A0A4W6CJ93
names: Similarity
messages: Belongs to the sulfatase family.

8187:pecam1a
gene id: 8187:pecam1a
uniprot id: A0A4W6BXP1
names: Subcellular Location Annotation
messages: Membrane

8187:gdnfa
gene id: 8187:gdnfa
uniprot id: A0A4W6D1R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Homodimer; disulfide-linked.
messages: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
messages: Secreted

8187:palm1b
gene id: 8187:palm1b
uniprot id: A0A4W6CTU6
names: Similarity
messages: Belongs to the paralemmin family.

8187:LOC108878702
gene id: 8187:LOC108878702
uniprot id: A0A4W6G5Q1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108883808
gene id: 8187:LOC108883808
uniprot id: A0A4W6FNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

8187:fbxo25
gene id: 8187:fbxo25
uniprot id: A0A4W6DAY3
uniprot id: A0A4W6DBE3
names: Subcellular Location Annotation
messages: Nucleus

8187:ercc5
gene id: 8187:ercc5
uniprot id: A0A4W6D9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

8187:dip2a
gene id: 8187:dip2a
uniprot id: A0A4W6FCF4
uniprot id: A0A4W6FD91
names: Similarity
messages: Belongs to the DIP2 family.

8187:LOC108898993
gene id: 8187:LOC108898993
uniprot id: A0A4W6E2Z9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:ggh
gene id: 8187:ggh
uniprot id: A0A4W6G7B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

8187:sprb
gene id: 8187:sprb
uniprot id: A0A4W6CCI6
names: Similarity
messages: Belongs to the sepiapterin reductase family.

8187:LOC108895834
gene id: 8187:LOC108895834
uniprot id: A0A4W6CEC6
names: Similarity
messages: Belongs to the serpin family.

8187:wnt16
gene id: 8187:wnt16
uniprot id: A0A4W6BZG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:elavl4
gene id: 8187:elavl4
uniprot id: A0A4W6G377
uniprot id: A0A4W6G4B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

8187:sema6bb
gene id: 8187:sema6bb
uniprot id: A0A4W6FW88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:unga
gene id: 8187:unga
uniprot id: A0A4W6G9T1
uniprot id: A0A4W6GB16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

8187:LOC108877025
gene id: 8187:LOC108877025
uniprot id: A0A4W6FPG2
names: Similarity
messages: Belongs to the peptidase C1 family.

8187:slc48a1b
gene id: 8187:slc48a1b
uniprot id: A0A4W6C4W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

8187:sema3ab
gene id: 8187:sema3ab
uniprot id: A0A4W6DF71
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108891643
gene id: 8187:LOC108891643
uniprot id: A0A4W6BMQ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:pus1
gene id: 8187:pus1
uniprot id: A0A4W6DE73
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8187:LOC108874054
gene id: 8187:LOC108874054
uniprot id: A0A4W6CHW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8187:LOC108884930
gene id: 8187:LOC108884930
uniprot id: A0A4W6CA57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

8187:ptpn2a
gene id: 8187:ptpn2a
uniprot id: A0A4W6EUU7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8187:chst11
gene id: 8187:chst11
uniprot id: A0A4W6ELL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108895415
gene id: 8187:LOC108895415
uniprot id: A0A4W6FS08
names: Similarity
messages: Belongs to the NKAP family.

8187:man1a2
gene id: 8187:man1a2
uniprot id: A0A4W6G0T7
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8187:LOC108898002
gene id: 8187:LOC108898002
uniprot id: A0A4W6DI25
names: Subcellular Location Annotation
messages: Nucleus

8187:tp53
gene id: 8187:tp53
uniprot id: A0A4W6CU25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

8187:LOC108901614
gene id: 8187:LOC108901614
uniprot id: A0A4W6CES8
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

8187:si:ch211-191a24.4
gene id: 8187:si:ch211-191a24.4
uniprot id: A0A4W6F6R3
names: Subcellular Location Annotation
messages: Membrane

8187:p4ha2
gene id: 8187:p4ha2
uniprot id: A0A4W6ECK3
uniprot id: A0A4W6EEN8
uniprot id: A0A4W6EH98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

8187:LOC108885765
gene id: 8187:LOC108885765
uniprot id: A0A4W6C0V3
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

8187:LOC108883535
gene id: 8187:LOC108883535
uniprot id: A0A4W6E4L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8187:ppp2r5b
gene id: 8187:ppp2r5b
uniprot id: A0A4W6EJY6
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8187:LOC108899508
gene id: 8187:LOC108899508
uniprot id: A0A4W6C5T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

8187:ncln
gene id: 8187:ncln
uniprot id: A0A4W6FSQ2
names: Similarity
messages: Belongs to the nicastrin family.

8187:LOC108899927
gene id: 8187:LOC108899927
uniprot id: A0A4W6FM98
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:parp16
gene id: 8187:parp16
uniprot id: A0A4W6CY43
names: Similarity
messages: Belongs to the ARTD/PARP family.

8187:LOC108889488
gene id: 8187:LOC108889488
uniprot id: A0A4W6E563
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

8187:tagln
gene id: 8187:tagln
uniprot id: A0A4W6DST2
names: Similarity
messages: Belongs to the calponin family.

8187:aqp3a
gene id: 8187:aqp3a
uniprot id: A0A4W6G7L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

8187:LOC108890511
gene id: 8187:LOC108890511
uniprot id: A0A4W6EGR0
names: Similarity
messages: Belongs to the PPDPF family.

8187:ube2b
gene id: 8187:ube2b
uniprot id: A0A4W6DSB3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:fam167ab
gene id: 8187:fam167ab
uniprot id: A0A4W6E1Q2
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

8187:srxn1
gene id: 8187:srxn1
uniprot id: A0A4W6EDH3
names: Similarity
messages: Belongs to the sulfiredoxin family.

8187:atpaf2
gene id: 8187:atpaf2
uniprot id: A0A4W6GAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

8187:bloc1s1
gene id: 8187:bloc1s1
uniprot id: A0A4W6E1E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Mitochondrion intermembrane space

8187:LOC108898662
gene id: 8187:LOC108898662
uniprot id: A0A4W6DHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:meis1b
gene id: 8187:meis1b
uniprot id: A0A4W6DTW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8187:ppm1la
gene id: 8187:ppm1la
uniprot id: A0A4W6E332
names: Similarity
messages: Belongs to the PP2C family.

8187:cdk2ap2
gene id: 8187:cdk2ap2
uniprot id: A0A4W6BR01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

8187:kcnk6
gene id: 8187:kcnk6
uniprot id: A0A4W6CYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8187:si:zfos-323e3.4
gene id: 8187:si:zfos-323e3.4
uniprot id: A0A4W6FU76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8187:LOC108880581
gene id: 8187:LOC108880581
uniprot id: A0A4W6CCJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

8187:eif4ea
gene id: 8187:eif4ea
uniprot id: A0A4W6FCB9
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8187:LOC108888922
gene id: 8187:LOC108888922
uniprot id: A0A4W6ELF3
uniprot id: A0A4W6EMF4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:nipsnap3a
gene id: 8187:nipsnap3a
uniprot id: A0A4W6C5L6
names: Similarity
messages: Belongs to the NipSnap family.

8187:ap2s1
gene id: 8187:ap2s1
uniprot id: A0A4W6EQJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

8187:eef1db
gene id: 8187:eef1db
uniprot id: A0A4W6FCN3
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

8187:fgf3
gene id: 8187:fgf3
uniprot id: A0A4W6ENA6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:nradd
gene id: 8187:nradd
uniprot id: A0A4W6DRN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108874909
gene id: 8187:LOC108874909
uniprot id: A0A4W6F3Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

8187:LOC108885082
gene id: 8187:LOC108885082
uniprot id: A0A4W6G6T2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8187:myoz1b
gene id: 8187:myoz1b
uniprot id: A0A4W6EK63
names: Similarity
messages: Belongs to the myozenin family.

8187:LOC108889340
gene id: 8187:LOC108889340
uniprot id: A0A4W6BRA4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:slc7a8a
gene id: 8187:slc7a8a
uniprot id: A0A4W6BNI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

8187:ecrg4a
gene id: 8187:ecrg4a
uniprot id: A0A4W6FGC3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

8187:taf5l
gene id: 8187:taf5l
uniprot id: A0A4W6G780
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

8187:LOC108873982
gene id: 8187:LOC108873982
uniprot id: A0A4W6CVX5
names: Similarity
messages: Belongs to the cornifelin family.

8187:LOC108882236
gene id: 8187:LOC108882236
uniprot id: A0A4W6CBA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8187:LOC108883395
gene id: 8187:LOC108883395
uniprot id: A0A4W6D2B4
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108873209
gene id: 8187:LOC108873209
uniprot id: A0A4W6BW05
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8187:slc29a3
gene id: 8187:slc29a3
uniprot id: A0A4W6BQ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

8187:mettl26
gene id: 8187:mettl26
uniprot id: A0A4W6C8Y2
names: Similarity
messages: Belongs to the UPF0585 family.

8187:rfx2
gene id: 8187:rfx2
uniprot id: A0A4W6CX96
uniprot id: A0A4W6CXB0
names: Subcellular Location Annotation
messages: Nucleus

8187:kcng3
gene id: 8187:kcng3
uniprot id: A0A4W6EKZ8
names: Subcellular Location Annotation
messages: Membrane

8187:arrdc3a
gene id: 8187:arrdc3a
uniprot id: A0A4W6G7C0
names: Similarity
messages: Belongs to the arrestin family.

8187:psmc2
gene id: 8187:psmc2
uniprot id: A0A4W6E5G0
names: Similarity
messages: Belongs to the AAA ATPase family.

8187:mocs3
gene id: 8187:mocs3
uniprot id: A0A4W6DZH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

8187:LOC108879413
gene id: 8187:LOC108879413
uniprot id: A0A4W6FY00
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108889331
gene id: 8187:LOC108889331
uniprot id: A0A4W6BW96
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:cldn11a
gene id: 8187:cldn11a
uniprot id: A0A4W6CU08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:snw1
gene id: 8187:snw1
uniprot id: A0A4W6D947
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

8187:gab3
gene id: 8187:gab3
uniprot id: A0A6M9QEL6
names: Similarity
messages: Belongs to the GAB family.

8187:fabp4b
gene id: 8187:fabp4b
uniprot id: A0A4W6DRT5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8187:LOC108876135
gene id: 8187:LOC108876135
uniprot id: A0A4W6DML5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

8187:bmp7b
gene id: 8187:bmp7b
uniprot id: A0A4W6EWV1
names: Similarity
messages: Belongs to the TGF-beta family.

8187:ak5
gene id: 8187:ak5
uniprot id: A0A4W6FUL3
names: Similarity
messages: Belongs to the adenylate kinase family.

8187:ntrk1
gene id: 8187:ntrk1
uniprot id: A0A4W6BMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8187:hepacam2
gene id: 8187:hepacam2
uniprot id: A0A4W6EU77
names: Subcellular Location Annotation
messages: Membrane

8187:hscb
gene id: 8187:hscb
uniprot id: A0A4W6EFS6
names: Similarity
messages: Belongs to the HscB family.

8187:sft2d2a
gene id: 8187:sft2d2a
uniprot id: A0A4W6DZ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

8187:got1l1
gene id: 8187:got1l1
uniprot id: A0A4W6G6S0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

8187:LOC108876328
gene id: 8187:LOC108876328
uniprot id: A0A4W6EV05
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:vgll2b
gene id: 8187:vgll2b
uniprot id: A0A4W6ET93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

8187:LOC108886603
gene id: 8187:LOC108886603
uniprot id: A0A4W6F717
names: Subcellular Location Annotation
messages: Cytoplasm

8187:uck2b
gene id: 8187:uck2b
uniprot id: A0A4W6FPV6
names: Similarity
messages: Belongs to the uridine kinase family.

8187:gcfc2
gene id: 8187:gcfc2
uniprot id: A0A4W6G104
names: Similarity
messages: Belongs to the GCF family.

8187:tmprss13a
gene id: 8187:tmprss13a
uniprot id: A0A4W6ECX4
names: Subcellular Location Annotation
messages: extracellular space

8187:sstr2a
gene id: 8187:sstr2a
uniprot id: A0A4W6CUK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

8187:LOC108893580
gene id: 8187:LOC108893580
uniprot id: A0A4W6CT52
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8187:dym
gene id: 8187:dym
uniprot id: A0A4W6CIQ9
names: Similarity
messages: Belongs to the dymeclin family.

8187:smim12
gene id: 8187:smim12
uniprot id: A0A4W6D2T2
names: Similarity
messages: Belongs to the SMIM12 family.

8187:tead1a
gene id: 8187:tead1a
uniprot id: A0A4W6EDK2
names: Subcellular Location Annotation
messages: Nucleus

8187:rab4b
gene id: 8187:rab4b
uniprot id: A0A4W6ERP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

8187:mau2
gene id: 8187:mau2
uniprot id: A0A4W6EB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

8187:polr3f
gene id: 8187:polr3f
uniprot id: A0A4W6E0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

8187:ctsf
gene id: 8187:ctsf
uniprot id: A0A4W6FTY6
names: Similarity
messages: Belongs to the peptidase C1 family.

8187:ikbke
gene id: 8187:ikbke
uniprot id: A0A4W6DMS0
names: Subcellular Location Annotation
messages: Cytoplasm

8187:tnip2
gene id: 8187:tnip2
uniprot id: A0A4W6EWX8
names: Subcellular Location Annotation
messages: Cytoplasm

8187:nadk2
gene id: 8187:nadk2
uniprot id: A0A4W6DG43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

8187:msto1
gene id: 8187:msto1
uniprot id: A0A4W6EDQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

8187:ndel1a
gene id: 8187:ndel1a
uniprot id: A0A4W6DZU9
uniprot id: A0A4W6E2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8187:hibadha
gene id: 8187:hibadha
uniprot id: A0A4W6E9Z0
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8187:zdhhc2
gene id: 8187:zdhhc2
uniprot id: A0A4W6BV01
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8187:ccnd1
gene id: 8187:ccnd1
uniprot id: A0A4W6BQI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:flt1
gene id: 8187:flt1
uniprot id: A0A4W6DQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8187:agpat9l
gene id: 8187:agpat9l
uniprot id: A0A4W6BUW0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8187:zdhhc11
gene id: 8187:zdhhc11
uniprot id: A0A4W6DNQ9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8187:evla
gene id: 8187:evla
uniprot id: A0A4W6F3P6
uniprot id: A0A4W6F5G1
uniprot id: A0A4W6F5G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

8187:LOC108883910
gene id: 8187:LOC108883910
uniprot id: A0A4W6CJ61
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

8187:brinp1
gene id: 8187:brinp1
uniprot id: A0A4W6CKP5
names: Similarity
messages: Belongs to the BRINP family.

8187:uox
gene id: 8187:uox
uniprot id: A0A4W6E5Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

8187:rhbdl1
gene id: 8187:rhbdl1
uniprot id: A0A4W6G297
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

8187:pde7a
gene id: 8187:pde7a
uniprot id: A0A4W6DPT9
uniprot id: A0A4W6DS48
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8187:LOC108885629
gene id: 8187:LOC108885629
uniprot id: A0A4W6FAX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The SEC61 channel-forming translocon complex consists of channel-forming core components SEC61A1, SEC61B and SEC61G and different auxiliary components such as SEC62 and SEC63 (By similarity). The SEC61 channel associates with the multi-pass translocon (MPT) complex.

8187:rplp2
gene id: 8187:rplp2
uniprot id: A0A4W6CCT6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

8187:spns2
gene id: 8187:spns2
uniprot id: A0A4W6EAK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

8187:synprb
gene id: 8187:synprb
uniprot id: A0A4W6DPN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8187:vamp3
gene id: 8187:vamp3
uniprot id: A0A4W6DKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8187:LOC108899599
gene id: 8187:LOC108899599
uniprot id: A0A4W6BT87
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:asic4a
gene id: 8187:asic4a
uniprot id: A0A4W6DI48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Cell membrane
messages: Membrane

8187:cacul1
gene id: 8187:cacul1
uniprot id: A0A4W6CTP7
names: Similarity
messages: Belongs to the cullin family.

8187:tm7sf3
gene id: 8187:tm7sf3
uniprot id: A0A4W6G0K5
names: Subcellular Location Annotation
messages: Membrane

8187:prdx2
gene id: 8187:prdx2
uniprot id: A0A4W6F480
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8187:pigu
gene id: 8187:pigu
uniprot id: A0A4W6DD39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108882192
gene id: 8187:LOC108882192
uniprot id: A0A4W6DZU0
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108882750
gene id: 8187:LOC108882750
uniprot id: A0A4W6BR40
names: Similarity
messages: Belongs to the SNF7 family.

8187:foxf2a
gene id: 8187:foxf2a
uniprot id: A0A4W6D5J1
names: Subcellular Location Annotation
messages: Nucleus

8187:foxg1c
gene id: 8187:foxg1c
uniprot id: A0A4W6G1W0
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108889285
gene id: 8187:LOC108889285
uniprot id: A0A4W6FX69
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8187:LOC108888180
gene id: 8187:LOC108888180
uniprot id: A0A4W6BPC7
names: Subcellular Location Annotation
messages: Membrane

8187:adra1ab
gene id: 8187:adra1ab
uniprot id: A0A4W6BZR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108877656
gene id: 8187:LOC108877656
uniprot id: A0A4W6DMC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8187:slc27a4
gene id: 8187:slc27a4
uniprot id: A0A4W6C5H0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8187:yeats4
gene id: 8187:yeats4
uniprot id: A0A4W6EHH8
names: Subcellular Location Annotation
messages: Nucleus

8187:sirt2
gene id: 8187:sirt2
uniprot id: A0A4W6E4G1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

8187:otud7b
gene id: 8187:otud7b
uniprot id: A0A4W6BVT2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:LOC108899794
gene id: 8187:LOC108899794
uniprot id: A0A4W6EYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8187:cct5
gene id: 8187:cct5
uniprot id: A0A4W6CGC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8187:gcdhb
gene id: 8187:gcdhb
uniprot id: A0A4W6EAH3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8187:tac3a
gene id: 8187:tac3a
uniprot id: A0A4W6FB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

8187:ube2g2
gene id: 8187:ube2g2
uniprot id: A0A4W6ETI8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:thbs3a
gene id: 8187:thbs3a
uniprot id: A0A4W6DRK7
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108872988
gene id: 8187:LOC108872988
uniprot id: A0A4W6FMT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Orphan receptor.

8187:hoga1
gene id: 8187:hoga1
uniprot id: A0A4W6EIP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

8187:gart
gene id: 8187:gart
uniprot id: A0A4W6DIG1
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

8187:ndc1
gene id: 8187:ndc1
uniprot id: A0A4W6EXR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

8187:LOC108880831
gene id: 8187:LOC108880831
uniprot id: A0A4W6EKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

8187:bcl7bb
gene id: 8187:bcl7bb
uniprot id: A0A4W6E902
names: Similarity
messages: Belongs to the BCL7 family.

8187:npepl1
gene id: 8187:npepl1
uniprot id: A0A4W6FXF1
names: Similarity
messages: Belongs to the peptidase M17 family.

8187:hrh2b
gene id: 8187:hrh2b
uniprot id: A0A4W6F5C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108880009
gene id: 8187:LOC108880009
uniprot id: A0A4W6DV48
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8187:mcm5
gene id: 8187:mcm5
uniprot id: A0A4W6F1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

8187:six3b
gene id: 8187:six3b
uniprot id: A0A4W6EHV4
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108898939
gene id: 8187:LOC108898939
uniprot id: A0A4W6FUQ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

8187:LOC108898963
gene id: 8187:LOC108898963
uniprot id: A0A4W6CNS5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:rnft2
gene id: 8187:rnft2
uniprot id: A0A4W6EF52
names: Subcellular Location Annotation
messages: Membrane

8187:dpt
gene id: 8187:dpt
uniprot id: A0A4W6DLC4
names: Similarity
messages: Belongs to the dermatopontin family.

8187:slc37a2
gene id: 8187:slc37a2
uniprot id: A0A4W6DHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8187:LOC108903131
gene id: 8187:LOC108903131
uniprot id: A0A4W6F7Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

8187:tbl3
gene id: 8187:tbl3
uniprot id: A0A4W6DW57
names: Subcellular Location Annotation
messages: nucleolus

8187:copb1
gene id: 8187:copb1
uniprot id: A0A4W6DPE7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

8187:hapln3
gene id: 8187:hapln3
uniprot id: A0A4W6FW04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108901531
gene id: 8187:LOC108901531
uniprot id: A0A4W6BN78
names: Similarity
messages: Belongs to the peptidase C1 family.

8187:prkd2
gene id: 8187:prkd2
uniprot id: A0A4W6EM97
uniprot id: A0A4W6ERJ5
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

8187:LOC108874995
gene id: 8187:LOC108874995
uniprot id: A0A4W6DVY7
names: Similarity
messages: Belongs to the ARTD/PARP family.

8187:rad50
gene id: 8187:rad50
uniprot id: A0A4W6EYQ6
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

8187:zhx2a
gene id: 8187:zhx2a
uniprot id: A0A4W6EBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8187:tfap2c
gene id: 8187:tfap2c
uniprot id: A0A4W6E9M6
uniprot id: A0A4W6EAV1
uniprot id: A0A4W6EAV5
names: Similarity
messages: Belongs to the AP-2 family.

8187:LOC108898709
gene id: 8187:LOC108898709
uniprot id: A0A4W6EC33
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:tor4aa
gene id: 8187:tor4aa
uniprot id: A0A4W6DFZ2
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

8187:psmd5
gene id: 8187:psmd5
uniprot id: A0A4W6BYZ7
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

8187:bcam
gene id: 8187:bcam
uniprot id: A0A4W6D9X8
uniprot id: A0A4W6D9Y7
uniprot id: A0A4W6DAD0
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108880953
gene id: 8187:LOC108880953
uniprot id: A0A4W6CGM1
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108886189
gene id: 8187:LOC108886189
uniprot id: A0A4W6BWH7
names: Subcellular Location Annotation
messages: Cytoplasm

8187:nudt3b
gene id: 8187:nudt3b
uniprot id: A0A4W6D7E7
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

8187:dctn5
gene id: 8187:dctn5
uniprot id: A0A4W6C5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

8187:plppr2a
gene id: 8187:plppr2a
uniprot id: A0A4W6E9Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8187:LOC108882927
gene id: 8187:LOC108882927
uniprot id: A0A4W6E577
names: Subcellular Location Annotation
messages: Membrane

8187:ahcyl2b
gene id: 8187:ahcyl2b
uniprot id: A0A4W6FLT8
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

8187:LOC108881803
gene id: 8187:LOC108881803
uniprot id: A0A4W6DXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8187:nfe2l3
gene id: 8187:nfe2l3
uniprot id: A0A4W6EC04
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8187:LOC108885467
gene id: 8187:LOC108885467
uniprot id: A0A4W6DII3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8187:LOC108876866
gene id: 8187:LOC108876866
uniprot id: A0A4W6FZF7
names: Subcellular Location Annotation
messages: Nucleus

8187:chchd4a
gene id: 8187:chchd4a
uniprot id: A0A4W6F8P2
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

8187:bmpr1aa
gene id: 8187:bmpr1aa
uniprot id: A0A4W6BW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8187:ifih1
gene id: 8187:ifih1
uniprot id: A0A4W6FY18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

8187:LOC108899812
gene id: 8187:LOC108899812
uniprot id: A0A4W6DXY3
names: Similarity
messages: Belongs to the DENND11 family.

8187:psat1
gene id: 8187:psat1
uniprot id: A0A4W6EX61
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

8187:LOC108887619
gene id: 8187:LOC108887619
uniprot id: A0A4W6BQK8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

8187:psma5
gene id: 8187:psma5
uniprot id: A0A4W6DL33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8187:LOC108886375
gene id: 8187:LOC108886375
uniprot id: A0A4W6CQJ5
names: Similarity
messages: Belongs to the NipSnap family.

8187:tars3
gene id: 8187:tars3
uniprot id: A0A4W6G627
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

8187:LOC108880692
gene id: 8187:LOC108880692
uniprot id: A0A4W6C3S6
uniprot id: A0A4W6C5Q6
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108881476
gene id: 8187:LOC108881476
uniprot id: A0A4W6ENB8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

8187:ggps1
gene id: 8187:ggps1
uniprot id: A0A4W6CD18
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8187:sybu
gene id: 8187:sybu
uniprot id: A0A4W6E7Z7
names: Subcellular Location Annotation
messages: Membrane

8187:ext1c
gene id: 8187:ext1c
uniprot id: A0A4W6DS51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8187:fermt1
gene id: 8187:fermt1
uniprot id: A0A4W6E0K0
names: Similarity
messages: Belongs to the kindlin family.

8187:ercc2
gene id: 8187:ercc2
uniprot id: A0A4W6D475
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

8187:LOC108889968
gene id: 8187:LOC108889968
uniprot id: A0A4W6CZD3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:tjp3
gene id: 8187:tjp3
uniprot id: A0A4W6D8R3
uniprot id: A0A4W6D921
names: Similarity
messages: Belongs to the MAGUK family.

8187:h3f3d
gene id: 8187:h3f3d
uniprot id: A0A4W6G137
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:stt3b
gene id: 8187:stt3b
uniprot id: A0A4W6DTJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

8187:ccdc39
gene id: 8187:ccdc39
uniprot id: A0A4W6FKF4
names: Similarity
messages: Belongs to the CCDC39 family.

8187:LOC108884428
gene id: 8187:LOC108884428
uniprot id: A0A4W6G7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

8187:dpysl2b
gene id: 8187:dpysl2b
uniprot id: A0A4W6C549
uniprot id: A0A4W6C8I5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8187:flot1a
gene id: 8187:flot1a
uniprot id: A0A4W6F592
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

8187:vps41
gene id: 8187:vps41
uniprot id: A0A4W6CPU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: clathrin-coated vesicle
messages: trans-Golgi network

8187:ints9
gene id: 8187:ints9
uniprot id: A0A4W6CEL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

8187:LOC108888496
gene id: 8187:LOC108888496
uniprot id: A0A4W6F2F9
uniprot id: A0A4W6F440
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8187:eva1c
gene id: 8187:eva1c
uniprot id: A0A4W6FX06
names: Similarity
messages: Belongs to the EVA1 family.

8187:LOC108880106
gene id: 8187:LOC108880106
uniprot id: A0A4W6F9F3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8187:epoa
gene id: 8187:epoa
uniprot id: A0A4W6E8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
messages: Secreted

8187:st18
gene id: 8187:st18
uniprot id: A0A4W6CID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

8187:isl1a
gene id: 8187:isl1a
uniprot id: A0A4W6E2T5
names: Subcellular Location Annotation
messages: Nucleus

8187:gata3
gene id: 8187:gata3
uniprot id: A0A4W6D4X6
names: Subcellular Location Annotation
messages: Nucleus

8187:rps5
gene id: 8187:rps5
uniprot id: A0A4W6E408
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

8187:LOC108886540
gene id: 8187:LOC108886540
uniprot id: A0A4W6ETR7
names: Subcellular Location Annotation
messages: Membrane

8187:ier5l
gene id: 8187:ier5l
uniprot id: A0A4W6F7J5
names: Similarity
messages: Belongs to the IER family.

8187:sars2
gene id: 8187:sars2
uniprot id: A0A4W6DFB0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

8187:marchf9
gene id: 8187:marchf9
uniprot id: A0A4W6BZG2
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108874723
gene id: 8187:LOC108874723
uniprot id: A0A4W6E9Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8187:slc6a9
gene id: 8187:slc6a9
uniprot id: A0A4W6CUZ5
uniprot id: A0A4W6CV33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

8187:ccn1
gene id: 8187:ccn1
uniprot id: A0A4W6FMV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:nup133
gene id: 8187:nup133
uniprot id: A0A4W6G9I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

8187:tha1
gene id: 8187:tha1
uniprot id: A0A4W6DMK6
names: Similarity
messages: Belongs to the threonine aldolase family.

8187:polr1b
gene id: 8187:polr1b
uniprot id: A0A4W6D232
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

8187:nptnb
gene id: 8187:nptnb
uniprot id: A0A4W6EME4
uniprot id: A0A4W6ERQ0
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108875914
gene id: 8187:LOC108875914
uniprot id: A0A4W6FP03
uniprot id: A0A4W6FP09
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8187:gpm6aa
gene id: 8187:gpm6aa
uniprot id: A0A4W6FAI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8187:LOC108878716
gene id: 8187:LOC108878716
uniprot id: A0A4W6FS31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8187:LOC108896255
gene id: 8187:LOC108896255
uniprot id: A0A4W6EWK0
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:srpra
gene id: 8187:srpra
uniprot id: A0A4W6CUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108900566
gene id: 8187:LOC108900566
uniprot id: A0A4W6FH62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8187:LOC108898577
gene id: 8187:LOC108898577
uniprot id: A0A4W6ELI0
uniprot id: A0A4W6ELI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8187:zgc:154075
gene id: 8187:zgc:154075
uniprot id: A0A4W6G8N5
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

8187:haus3
gene id: 8187:haus3
uniprot id: A0A4W6D1Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

8187:lg4h5orf22
gene id: 8187:lg4h5orf22
uniprot id: A0A4W6G6E9
names: Similarity
messages: Belongs to the UPF0489 family.

8187:unc119b
gene id: 8187:unc119b
uniprot id: A0A4W6F5G5
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8187:adss1
gene id: 8187:adss1
uniprot id: A0A4W6DSW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8187:sec22bb
gene id: 8187:sec22bb
uniprot id: A0A4W6FU23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8187:LOC108898287
gene id: 8187:LOC108898287
uniprot id: A0A4W6E718
names: Similarity
messages: Belongs to the cystatin family.

8187:itgb1a
gene id: 8187:itgb1a
uniprot id: A0A4W6G7Q4
uniprot id: A0A4W6G8M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

8187:LOC108891038
gene id: 8187:LOC108891038
uniprot id: A0A4W6F825
names: Subcellular Location Annotation
messages: Nucleus

8187:hs6st3b
gene id: 8187:hs6st3b
uniprot id: A0A4W6FYX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8187:npr1b
gene id: 8187:npr1b
uniprot id: A0A4W6DBN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8187:ctsk
gene id: 8187:ctsk
uniprot id: A0A4W6CFL8
names: Similarity
messages: Belongs to the peptidase C1 family.

8187:mrpl17
gene id: 8187:mrpl17
uniprot id: A0A4W6BI27
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

8187:LOC108884107
gene id: 8187:LOC108884107
uniprot id: A0A4W6C910
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8187:kcnj1a.1
gene id: 8187:kcnj1a.1
uniprot id: A0A4W6CUS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8187:LOC108889007
gene id: 8187:LOC108889007
uniprot id: A0A4W6D3Y5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8187:vps29
gene id: 8187:vps29
uniprot id: A0A4W6EE14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

8187:zgc:114188
gene id: 8187:zgc:114188
uniprot id: A0A4W6FE15
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

8187:parla
gene id: 8187:parla
uniprot id: A0A4W6E3F5
names: Subcellular Location Annotation
messages: Membrane

8187:bbox1
gene id: 8187:bbox1
uniprot id: A0A4W6EQS9
names: Function
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.

8187:khdrbs1a
gene id: 8187:khdrbs1a
uniprot id: A0A4W6D6N6
names: Similarity
messages: Belongs to the KHDRBS family.

8187:LOC108885545
gene id: 8187:LOC108885545
uniprot id: A0A4W6EP47
uniprot id: A0A4W6ER41
names: Similarity
messages: Belongs to the beta-catenin family.

8187:LOC108900177
gene id: 8187:LOC108900177
uniprot id: A0A4W6EPH9
uniprot id: A0A4W6EQD2
names: Similarity
messages: Belongs to the BicD family.

8187:LOC108882747
gene id: 8187:LOC108882747
uniprot id: A0A4W6BV45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8187:LOC108880513
gene id: 8187:LOC108880513
uniprot id: A0A4W6DZG5
names: Subcellular Location Annotation
messages: Endomembrane system

8187:pax1a
gene id: 8187:pax1a
uniprot id: A0A4W6DWA5
names: Subcellular Location Annotation
messages: Nucleus

8187:snx13
gene id: 8187:snx13
uniprot id: A0A4W6EYS8
names: Similarity
messages: Belongs to the sorting nexin family.

8187:LOC108875877
gene id: 8187:LOC108875877
uniprot id: A0A4W6FWK1
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8187:map6b
gene id: 8187:map6b
uniprot id: A0A4W6FHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

8187:LOC108897062
gene id: 8187:LOC108897062
uniprot id: A0A4W6ECA8
names: Similarity
messages: Belongs to the peptidase C2 family.

8187:zfpm2a
gene id: 8187:zfpm2a
uniprot id: A0A4W6E4L5
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108899350
gene id: 8187:LOC108899350
uniprot id: A0A4W6DQE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:dnajc25
gene id: 8187:dnajc25
uniprot id: A0A4W6C0J4
names: Similarity
messages: Belongs to the DNAJC25 family.

8187:LOC108872980
gene id: 8187:LOC108872980
uniprot id: A0A4W6G2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

8187:urm1
gene id: 8187:urm1
uniprot id: A0A4W6C2T0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Cytoplasm

8187:LOC108900299
gene id: 8187:LOC108900299
uniprot id: A0A4W6C709
names: Similarity
messages: Belongs to the SH3BGR family.

8187:prkab2
gene id: 8187:prkab2
uniprot id: A0A4W6E9Z9
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

8187:dop1a
gene id: 8187:dop1a
uniprot id: A0A4W6E4S2
names: Similarity
messages: Belongs to the dopey family.

8187:cdc20
gene id: 8187:cdc20
uniprot id: A0A4W6DTX4
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8187:efemp1
gene id: 8187:efemp1
uniprot id: A0A4W6DUQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:zc3hc1
gene id: 8187:zc3hc1
uniprot id: A0A4W6FBN5
names: Subcellular Location Annotation
messages: Nucleus

8187:pik3ip1
gene id: 8187:pik3ip1
uniprot id: A0A4W6GBG9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:itgb2
gene id: 8187:itgb2
uniprot id: A0A4W6G6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

8187:LOC108878907
gene id: 8187:LOC108878907
uniprot id: A0A4W6E2F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:LOC108895447
gene id: 8187:LOC108895447
uniprot id: A0A4W6CYZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8187:srpx2
gene id: 8187:srpx2
uniprot id: A0A4W6EBX3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:dnaja2a
gene id: 8187:dnaja2a
uniprot id: A0A4W6G317
names: Subcellular Location Annotation
messages: Membrane

8187:pigc
gene id: 8187:pigc
uniprot id: A0A4W6CW81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

8187:snx3
gene id: 8187:snx3
uniprot id: A0A4W6CF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

8187:pms1
gene id: 8187:pms1
uniprot id: A0A4W6BJC3
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

8187:ccnb3
gene id: 8187:ccnb3
uniprot id: A0A4W6FQL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:rad51d
gene id: 8187:rad51d
uniprot id: A0A4W6CTQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus

8187:LOC108886501
gene id: 8187:LOC108886501
uniprot id: A0A4W6ERZ0
names: Similarity
messages: Belongs to the SZRD1 family.

8187:mthfr
gene id: 8187:mthfr
uniprot id: A0A4W6CQF3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

8187:cldn35
gene id: 8187:cldn35
uniprot id: A0A4W6F1F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8187:LOC108880871
gene id: 8187:LOC108880871
uniprot id: A0A4W6FZ35
names: Similarity
messages: Belongs to the peptidase M14 family.

8187:rpf2
gene id: 8187:rpf2
uniprot id: A0A4W6BXD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

8187:tdp1
gene id: 8187:tdp1
uniprot id: A0A4W6G4N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

8187:LOC108883520
gene id: 8187:LOC108883520
uniprot id: A0A4W6E428
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

8187:chmp2ba
gene id: 8187:chmp2ba
uniprot id: A0A4W6FGA6
names: Similarity
messages: Belongs to the SNF7 family.

8187:LOC108896866
gene id: 8187:LOC108896866
uniprot id: A0A4W6EH64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8187:nsa2
gene id: 8187:nsa2
uniprot id: A0A4W6F1Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

8187:LOC108891701
gene id: 8187:LOC108891701
uniprot id: A0A4W6G555
names: Subcellular Location Annotation
messages: extracellular space

8187:LOC108872735
gene id: 8187:LOC108872735
uniprot id: A0A4W6F1U3
names: Subcellular Location Annotation
messages: sarcolemma

8187:plp2b
gene id: 8187:plp2b
uniprot id: A0A4W6DZM5
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108880551
gene id: 8187:LOC108880551
uniprot id: A0A4W6DZH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

8187:hoxa10b
gene id: 8187:hoxa10b
uniprot id: A0A4W6DK30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8187:mtfr1l
gene id: 8187:mtfr1l
uniprot id: A0A4W6F550
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

8187:stag1a
gene id: 8187:stag1a
uniprot id: A0A4W6DVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

8187:LOC108896681
gene id: 8187:LOC108896681
uniprot id: A0A4W6BV43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8187:LOC108898952
gene id: 8187:LOC108898952
uniprot id: A0A4W6F0F7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:phf8
gene id: 8187:phf8
uniprot id: A0A4W6ERU6
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8187:smpdl3b
gene id: 8187:smpdl3b
uniprot id: A0A4W6DGL4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

8187:sgpl1
gene id: 8187:sgpl1
uniprot id: A0A4W6CZJ9
names: Similarity
messages: Belongs to the group II decarboxylase family.

8187:dctn1a
gene id: 8187:dctn1a
uniprot id: A0A4W6EH97
uniprot id: A0A4W6EJM9
uniprot id: A0A4W6EJP2
uniprot id: A0A4W6EMI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cell cortex
messages: cytoskeleton

8187:tmbim1a
gene id: 8187:tmbim1a
uniprot id: A0A4W6CA14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8187:mppe1
gene id: 8187:mppe1
uniprot id: A0A4W6FSC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

8187:LOC108895868
gene id: 8187:LOC108895868
uniprot id: A0A4W6FH02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:zer1
gene id: 8187:zer1
uniprot id: A0A4W6DI29
names: Similarity
messages: Belongs to the zyg-11 family.

8187:LOC108901041
gene id: 8187:LOC108901041
uniprot id: A0A4W6FKV1
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108895898
gene id: 8187:LOC108895898
uniprot id: A0A4W6FIZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:tpp2
gene id: 8187:tpp2
uniprot id: A0A4W6D9K9
uniprot id: A0A4W6D9N3
names: Similarity
messages: Belongs to the peptidase S8 family.

8187:bicc2
gene id: 8187:bicc2
uniprot id: A0A4W6BW34
names: Similarity
messages: Belongs to the BicC family.

8187:LOC108901706
gene id: 8187:LOC108901706
uniprot id: A0A4W6BRW1
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

8187:ehd4
gene id: 8187:ehd4
uniprot id: A0A4W6DJ27
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8187:slc45a1
gene id: 8187:slc45a1
uniprot id: A0A4W6FNT3
names: Subcellular Location Annotation
messages: Membrane

8187:si:dkey-119f1.1
gene id: 8187:si:dkey-119f1.1
uniprot id: A0A4W6DE06
names: Subcellular Location Annotation
messages: Chromosome

8187:nmnat2
gene id: 8187:nmnat2
uniprot id: A0A4W6C654
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

8187:cpxm2
gene id: 8187:cpxm2
uniprot id: A0A4W6F5F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

8187:slc15a1a
gene id: 8187:slc15a1a
uniprot id: A0A4W6G4P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

8187:ralba
gene id: 8187:ralba
uniprot id: A0A4W6DCV2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8187:coro2ba
gene id: 8187:coro2ba
uniprot id: A0A4W6F7H3
names: Similarity
messages: Belongs to the WD repeat coronin family.

8187:vbp1
gene id: 8187:vbp1
uniprot id: A0A4W6CDL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

8187:gja9a
gene id: 8187:gja9a
uniprot id: A0A4W6C7C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8187:LOC108878742
gene id: 8187:LOC108878742
uniprot id: A0A4W6GB24
names: Similarity
messages: Belongs to the arrestin family.

8187:LOC108885311
gene id: 8187:LOC108885311
uniprot id: A0A4W6CHZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8187:lhcgr
gene id: 8187:lhcgr
uniprot id: A0A4W6F3Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

8187:napba
gene id: 8187:napba
uniprot id: A0A4W6BVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

8187:pcsk9
gene id: 8187:pcsk9
uniprot id: A0A4W6CR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Endosome
messages: Golgi apparatus
messages: Lysosome

8187:rpl13a
gene id: 8187:rpl13a
uniprot id: A0A4W6F379
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

8187:rbfox1l
gene id: 8187:rbfox1l
uniprot id: A0A4W6D338
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

8187:trnau1apb
gene id: 8187:trnau1apb
uniprot id: A0A4W6E3E2
names: Similarity
messages: Belongs to the RRM TRSPAP family.

8187:foxa2
gene id: 8187:foxa2
uniprot id: A0A4W6DVH8
names: Subcellular Location Annotation
messages: Nucleus

8187:pnp6
gene id: 8187:pnp6
uniprot id: A0A4W6DTZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8187:orai1b
gene id: 8187:orai1b
uniprot id: A0A4W6CMH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8187:polr2c
gene id: 8187:polr2c
uniprot id: A0A4W6CZR6
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

8187:htr7c
gene id: 8187:htr7c
uniprot id: A0A4W6ER40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:agbl5
gene id: 8187:agbl5
uniprot id: A0A4W6DAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

8187:top1b
gene id: 8187:top1b
uniprot id: A0A4W6F5H7
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

8187:cavin4a
gene id: 8187:cavin4a
uniprot id: A0A4W6CL99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8187:cbr1
gene id: 8187:cbr1
uniprot id: A0A4W6BKL6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:nudt18
gene id: 8187:nudt18
uniprot id: A0A4W6DWT9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

8187:LOC108892856
gene id: 8187:LOC108892856
uniprot id: A0A4W6F4W8
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8187:scamp2l
gene id: 8187:scamp2l
uniprot id: A0A4W6F104
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8187:LOC108884156
gene id: 8187:LOC108884156
uniprot id: A0A4W6E8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8187:dusp16
gene id: 8187:dusp16
uniprot id: A0A4W6F1M9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8187:rdh14b
gene id: 8187:rdh14b
uniprot id: A0A4W6EJF3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:dusp5
gene id: 8187:dusp5
uniprot id: A0A4W6DEE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8187:rpl7a
gene id: 8187:rpl7a
uniprot id: A0A4W6BLZ0
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

8187:st8sia3
gene id: 8187:st8sia3
uniprot id: A0A4W6BS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8187:tmem9
gene id: 8187:tmem9
uniprot id: A0A4W6F6R8
names: Similarity
messages: Belongs to the TMEM9 family.

8187:prickle2b
gene id: 8187:prickle2b
uniprot id: A0A4W6D6P0
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8187:LOC108892277
gene id: 8187:LOC108892277
uniprot id: A0A4W6DGW3
uniprot id: A0A4W6DHI8
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

8187:LOC108883859
gene id: 8187:LOC108883859
uniprot id: A0A4W6C388
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108881693
gene id: 8187:LOC108881693
uniprot id: A0A4W6BHV4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:cat
gene id: 8187:cat
uniprot id: A0A4W6CPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

8187:actr10
gene id: 8187:actr10
uniprot id: A0A4W6DP10
names: Similarity
messages: Belongs to the actin family.

8187:adgrg1
gene id: 8187:adgrg1
uniprot id: A0A4W6G0C2
names: Subcellular Location Annotation
messages: Membrane

8187:ddit3
gene id: 8187:ddit3
uniprot id: A0A4W6EDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

8187:LOC108893211
gene id: 8187:LOC108893211
uniprot id: A0A4W6EZR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8187:LOC108889071
gene id: 8187:LOC108889071
uniprot id: A0A4W6EP83
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8187:slc7a10a
gene id: 8187:slc7a10a
uniprot id: A0A4W6G2M4
names: Subcellular Location Annotation
messages: Membrane

8187:cntn2
gene id: 8187:cntn2
uniprot id: A0A4W6E8V7
names: Subcellular Location Annotation
messages: Membrane

8187:tmcc2
gene id: 8187:tmcc2
uniprot id: A0A4W6ELP2
names: Similarity
messages: Belongs to the TEX28 family.

8187:psma2a
gene id: 8187:psma2a
uniprot id: A0A4W6E9X2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8187:dpysl2a
gene id: 8187:dpysl2a
uniprot id: A0A4W6G636
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8187:bambia
gene id: 8187:bambia
uniprot id: A0A4W6G8U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

8187:htatsf1
gene id: 8187:htatsf1
uniprot id: A0A4W6F4T5
names: Similarity
messages: Belongs to the HTATSF1 family.

8187:slc49a4
gene id: 8187:slc49a4
uniprot id: A0A4W6EMN4
names: Subcellular Location Annotation
messages: Membrane

8187:mettl4
gene id: 8187:mettl4
uniprot id: A0A4W6CJB3
names: Similarity
messages: Belongs to the MT-A70-like family.

8187:LOC108890838
gene id: 8187:LOC108890838
uniprot id: A0A4W6EDK7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108892529
gene id: 8187:LOC108892529
uniprot id: A0A4W6EZI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

8187:si:ch211-244b2.4
gene id: 8187:si:ch211-244b2.4
uniprot id: A0A4W6E3X6
names: Similarity
messages: Belongs to the ARTD/PARP family.

8187:LOC108882755
gene id: 8187:LOC108882755
uniprot id: A0A4W6BR83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8187:apoc1
gene id: 8187:apoc1
uniprot id: A0A4W6DAT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Secreted

8187:il10
gene id: 8187:il10
uniprot id: A0A4W6DP59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

8187:clcf1
gene id: 8187:clcf1
uniprot id: A0A4W6DG44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

8187:serpine2
gene id: 8187:serpine2
uniprot id: A0A4W6C3N3
names: Similarity
messages: Belongs to the serpin family.

8187:LOC108886466
gene id: 8187:LOC108886466
uniprot id: A0A4W6G1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

8187:LOC108885251
gene id: 8187:LOC108885251
uniprot id: A0A4W6ETZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8187:LOC108882265
gene id: 8187:LOC108882265
uniprot id: A0A4W6E0N1
names: Similarity
messages: Belongs to the spectrin family.

8187:rps27.2
gene id: 8187:rps27.2
uniprot id: A0A4W6FB91
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8187:inpp5l
gene id: 8187:inpp5l
uniprot id: A0A4W6G7L5
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

8187:vps25
gene id: 8187:vps25
uniprot id: A0A4W6CYS6
names: Similarity
messages: Belongs to the VPS25 family.

8187:stra6
gene id: 8187:stra6
uniprot id: A0A4W6DI15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108879613
gene id: 8187:LOC108879613
uniprot id: A0A4W6FBK7
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108890060
gene id: 8187:LOC108890060
uniprot id: A0A4W6EI88
names: Similarity
messages: Belongs to the AHA1 family.

8187:tnfsf14
gene id: 8187:tnfsf14
uniprot id: A0A4W6FU25
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8187:slc16a4
gene id: 8187:slc16a4
uniprot id: A0A4W6CG19
names: Subcellular Location Annotation
messages: Membrane

8187:tmem131
gene id: 8187:tmem131
uniprot id: A0A4W6DRY8
names: Similarity
messages: Belongs to the TMEM131 family.

8187:ints10
gene id: 8187:ints10
uniprot id: A0A4W6BYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

8187:impdh2
gene id: 8187:impdh2
uniprot id: A0A4W6GA60
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

8187:LOC108893427
gene id: 8187:LOC108893427
uniprot id: A0A4W6EKW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:prpf31
gene id: 8187:prpf31
uniprot id: A0A4W6D3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

8187:LOC108891696
gene id: 8187:LOC108891696
uniprot id: A0A4W6G601
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:znf330
gene id: 8187:znf330
uniprot id: A0A4W6EZR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

8187:fam53b
gene id: 8187:fam53b
uniprot id: A0A4W6F6C4
names: Similarity
messages: Belongs to the FAM53 family.

8187:gcnt3
gene id: 8187:gcnt3
uniprot id: A0A4W6DCV6
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8187:agtrap
gene id: 8187:agtrap
uniprot id: A0A4W6EJU2
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108879964
gene id: 8187:LOC108879964
uniprot id: A0A4W6CT11
names: Subcellular Location Annotation
messages: Nucleus

8187:fgfbp3
gene id: 8187:fgfbp3
uniprot id: A0A4W6BS09
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8187:prlra
gene id: 8187:prlra
uniprot id: A0A4W6CFQ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

8187:htr6
gene id: 8187:htr6
uniprot id: A0A4W6CJF9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:LOC108896882
gene id: 8187:LOC108896882
uniprot id: A0A4W6EN77
names: Similarity
messages: Belongs to the SOGA family.

8187:polr2j
gene id: 8187:polr2j
uniprot id: A0A4W6FI21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

8187:efna1b
gene id: 8187:efna1b
uniprot id: A0A4W6FVH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:arg2
gene id: 8187:arg2
uniprot id: A0A4W6FDV5
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

8187:LOC108898156
gene id: 8187:LOC108898156
uniprot id: A0A4W6DZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8187:LOC108881277
gene id: 8187:LOC108881277
uniprot id: A0A4W6F0V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8187:get1
gene id: 8187:get1
uniprot id: A0A4W6CUZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:hspb7
gene id: 8187:hspb7
uniprot id: A0A4W6BPX9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8187:lzts2a
gene id: 8187:lzts2a
uniprot id: A0A4W6DTS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

8187:LOC108882943
gene id: 8187:LOC108882943
uniprot id: A0A4W6E5Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8187:slc25a1b
gene id: 8187:slc25a1b
uniprot id: A0A4W6CGH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:renbp
gene id: 8187:renbp
uniprot id: A0A4W6CXX6
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

8187:fitm1l
gene id: 8187:fitm1l
uniprot id: A0A4W6E1W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol.
messages: Membrane

8187:LOC108878002
gene id: 8187:LOC108878002
uniprot id: A0A4W6GAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8187:mfsd9
gene id: 8187:mfsd9
uniprot id: A0A4W6CSK6
names: Subcellular Location Annotation
messages: Membrane

8187:kcnk12
gene id: 8187:kcnk12
uniprot id: A0A4W6F2M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8187:c1galt1la
gene id: 8187:c1galt1la
uniprot id: A0A4W6FA91
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108898574
gene id: 8187:LOC108898574
uniprot id: A0A4W6EIU5
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108887524
gene id: 8187:LOC108887524
uniprot id: A0A4W6FMJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8187:muc13b
gene id: 8187:muc13b
uniprot id: A0A4W6E599
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:gss
gene id: 8187:gss
uniprot id: A0A4W6DCE0
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

8187:tafa5l
gene id: 8187:tafa5l
uniprot id: A0A4W6BZW7
names: Similarity
messages: Belongs to the TAFA family.

8187:homer2
gene id: 8187:homer2
uniprot id: A0A4W6C9V7
uniprot id: A0A4W6CG62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8187:nsun4
gene id: 8187:nsun4
uniprot id: A0A4W6FAK7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8187:afg1lb
gene id: 8187:afg1lb
uniprot id: A0A4W6CKC5
names: Similarity
messages: Belongs to the AFG1 ATPase family.

8187:cpsf6
gene id: 8187:cpsf6
uniprot id: A0A4W6EE13
uniprot id: A0A4W6EGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

8187:supt20
gene id: 8187:supt20
uniprot id: A0A4W6FQP8
names: Similarity
messages: Belongs to the SPT20 family.

8187:LOC108873375
gene id: 8187:LOC108873375
uniprot id: A0A4W6E6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8187:med30
gene id: 8187:med30
uniprot id: A0A4W6ER21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8187:fam219ab
gene id: 8187:fam219ab
uniprot id: A0A4W6G784
names: Similarity
messages: Belongs to the FAM219 family.

8187:ntf3
gene id: 8187:ntf3
uniprot id: A0A4W6FX55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

8187:esrrb
gene id: 8187:esrrb
uniprot id: A0A4W6EW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8187:aifm1
gene id: 8187:aifm1
uniprot id: A0A4W6FC26
uniprot id: A0A4W6FCV9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

8187:LOC108879154
gene id: 8187:LOC108879154
uniprot id: A0A4W6CM16
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:elovl4b
gene id: 8187:elovl4b
uniprot id: A0A4W6EHX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Oligomer.

8187:mdh1ab
gene id: 8187:mdh1ab
uniprot id: A0A4W6DUM0
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

8187:LOC108900311
gene id: 8187:LOC108900311
uniprot id: A0A4W6CFY6
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

8187:etv1
gene id: 8187:etv1
uniprot id: A0A4W6CPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:b4galnt3b
gene id: 8187:b4galnt3b
uniprot id: A0A4W6DB18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

8187:zgc:112408
gene id: 8187:zgc:112408
uniprot id: A0A4W6G548
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8187:nkx2.2a
gene id: 8187:nkx2.2a
uniprot id: A0A4W6DVF8
names: Subcellular Location Annotation
messages: Nucleus

8187:pi4k2a
gene id: 8187:pi4k2a
uniprot id: A0A4W6CJM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

8187:med1
gene id: 8187:med1
uniprot id: A0A4W6BV34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8187:kcnt1a
gene id: 8187:kcnt1a
uniprot id: A0A4W6BRI8
uniprot id: A0A4W6BSA6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:nfe2
gene id: 8187:nfe2
uniprot id: A0A4W6FLS2
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8187:LOC108897040
gene id: 8187:LOC108897040
uniprot id: A0A4W6DTZ4
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8187:LOC108899816
gene id: 8187:LOC108899816
uniprot id: A0A4W6DZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
messages: Secreted

8187:LOC108882168
gene id: 8187:LOC108882168
uniprot id: A0A4W6DTG6
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108886526
gene id: 8187:LOC108886526
uniprot id: A0A4W6EUT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8187:LOC108888568
gene id: 8187:LOC108888568
uniprot id: A0A4W6F9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

8187:rundc3aa
gene id: 8187:rundc3aa
uniprot id: A0A4W6CL69
names: Similarity
messages: Belongs to the RUNDC3 family.

8187:arl3b
gene id: 8187:arl3b
uniprot id: A0A4W6DUT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8187:foxb1a
gene id: 8187:foxb1a
uniprot id: A0A4W6DD51
names: Subcellular Location Annotation
messages: Nucleus

8187:slc25a24l
gene id: 8187:slc25a24l
uniprot id: A0A4W6FUG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8187:smarca5
gene id: 8187:smarca5
uniprot id: A0A4W6EX35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

8187:fez1
gene id: 8187:fez1
uniprot id: A0A4W6DWB6
names: Similarity
messages: Belongs to the zygin family.

8187:pcolce2b
gene id: 8187:pcolce2b
uniprot id: A0A4W6D3N7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:casq1a
gene id: 8187:casq1a
uniprot id: A0A4W6CL41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8187:slc5a7a
gene id: 8187:slc5a7a
uniprot id: A0A4W6C9F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8187:lhfpl3
gene id: 8187:lhfpl3
uniprot id: A0A4W6BZD3
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108889547
gene id: 8187:LOC108889547
uniprot id: A0A4W6CDX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

8187:mapre3a
gene id: 8187:mapre3a
uniprot id: A0A4W6ETK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8187:lrrc24
gene id: 8187:lrrc24
uniprot id: A0A4W6CUP5
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108902972
gene id: 8187:LOC108902972
uniprot id: A0A4W6BVJ3
names: Similarity
messages: Belongs to the globin family.

8187:cnmd
gene id: 8187:cnmd
uniprot id: A0A4W6C9D9
names: Similarity
messages: Belongs to the chondromodulin-1 family.

8187:tyw1
gene id: 8187:tyw1
uniprot id: A0A4W6CX17
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

8187:LOC108874072
gene id: 8187:LOC108874072
uniprot id: A0A4W6C426
uniprot id: A0A4W6CAP6
names: Similarity
messages: Belongs to the CD36 family.

8187:tmem30c
gene id: 8187:tmem30c
uniprot id: A0A4W6D9M9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8187:cacng8b
gene id: 8187:cacng8b
uniprot id: A0A4W6D8L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8187:foxe3
gene id: 8187:foxe3
uniprot id: A0A4W6DIL3
names: Subcellular Location Annotation
messages: Nucleus

8187:wdr82
gene id: 8187:wdr82
uniprot id: A0A4W6CAK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

8187:fgd6
gene id: 8187:fgd6
uniprot id: A0A4W6G3M4
names: Subcellular Location Annotation
messages: cytoskeleton

8187:cth1
gene id: 8187:cth1
uniprot id: A0A4W6EGP6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8187:crybgx
gene id: 8187:crybgx
uniprot id: A0A4W6CD54
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:LOC108891072
gene id: 8187:LOC108891072
uniprot id: A0A4W6DDV1
names: Similarity
messages: Belongs to the S-100 family.

8187:crcp
gene id: 8187:crcp
uniprot id: A0A4W6F5N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

8187:gng2
gene id: 8187:gng2
uniprot id: A0A4W6FRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8187:tmed4
gene id: 8187:tmed4
uniprot id: A0A4W6FHH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:zgc:114119
gene id: 8187:zgc:114119
uniprot id: A0A4W6FW13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8187:LOC108883613
gene id: 8187:LOC108883613
uniprot id: A0A4W6EIZ9
uniprot id: A0A4W6EK24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8187:kmt2bb
gene id: 8187:kmt2bb
uniprot id: A0A4W6CYG8
names: Subcellular Location Annotation
messages: Nucleus

8187:hoxd12a
gene id: 8187:hoxd12a
uniprot id: A0A4W6EAA8
names: Subcellular Location Annotation
messages: Nucleus

8187:tmem205
gene id: 8187:tmem205
uniprot id: A0A4W6ECE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

8187:parp1
gene id: 8187:parp1
uniprot id: A0A4W6D8R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

8187:LOC108882817
gene id: 8187:LOC108882817
uniprot id: A0A4W6CTB2
uniprot id: A0A4W6CTP0
uniprot id: A0A4W6CTV6
names: Similarity
messages: Belongs to the RRM CPEB family.

8187:LOC108882567
gene id: 8187:LOC108882567
uniprot id: A0A4W6GAG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8187:slc7a1a
gene id: 8187:slc7a1a
uniprot id: A0A4W6DC21
uniprot id: A0A4W6DCJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8187:ubl3a
gene id: 8187:ubl3a
uniprot id: A0A4W6FJK0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108882929
gene id: 8187:LOC108882929
uniprot id: A0A4W6E6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

8187:scube1
gene id: 8187:scube1
uniprot id: A0A4W6ERF5
uniprot id: A0A4W6ESC7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:gsta.1
gene id: 8187:gsta.1
uniprot id: A0A4W6DZI7
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

8187:LOC108887838
gene id: 8187:LOC108887838
uniprot id: A0A4W6ES18
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

8187:ptger3
gene id: 8187:ptger3
uniprot id: A0A4W6DU29
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:pgm2l1
gene id: 8187:pgm2l1
uniprot id: A0A4W6DY17
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8187:si:ch211-1i11.3
gene id: 8187:si:ch211-1i11.3
uniprot id: A0A4W6C1J0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8187:LOC108883853
gene id: 8187:LOC108883853
uniprot id: A0A4W6C279
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

8187:LOC108899496
gene id: 8187:LOC108899496
uniprot id: A0A4W6BSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

8187:eef1a1a
gene id: 8187:eef1a1a
uniprot id: A0A4W6DX00
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8187:tegt
gene id: 8187:tegt
uniprot id: A0A4W6C069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8187:fam162a
gene id: 8187:fam162a
uniprot id: A0A4W6DLJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

8187:ctnnb1
gene id: 8187:ctnnb1
uniprot id: A0A4W6EF67
names: Similarity
messages: Belongs to the beta-catenin family.

8187:LOC108901368
gene id: 8187:LOC108901368
uniprot id: A0A4W6D0E6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:gng7
gene id: 8187:gng7
uniprot id: A0A4W6DYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8187:nop14
gene id: 8187:nop14
uniprot id: A0A4W6CFQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

8187:adprs
gene id: 8187:adprs
uniprot id: A0A4W6FAY6
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

8187:ccka
gene id: 8187:ccka
uniprot id: A0A4W6EDT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

8187:plpp5
gene id: 8187:plpp5
uniprot id: A0A4W6C125
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8187:man2c1
gene id: 8187:man2c1
uniprot id: A0A4W6DGM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

8187:csnk2b
gene id: 8187:csnk2b
uniprot id: A0A4W6E5X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

8187:psmg1
gene id: 8187:psmg1
uniprot id: A0A4W6DG71
names: Similarity
messages: Belongs to the PSMG1 family.

8187:nupr1b
gene id: 8187:nupr1b
uniprot id: A0A4W6D569
names: Similarity
messages: Belongs to the NUPR family.

8187:mmab
gene id: 8187:mmab
uniprot id: A0A4W6G9M8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

8187:LOC108884705
gene id: 8187:LOC108884705
uniprot id: A0A4W6DGU8
names: Similarity
messages: Belongs to the ANKRD34 family.

8187:en2a
gene id: 8187:en2a
uniprot id: A0A4W6FFR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

8187:atxn7l3a
gene id: 8187:atxn7l3a
uniprot id: A0A4W6CMD6
uniprot id: A0A4W6CMF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of some SAGA transcription coactivator-HAT complexes. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain forms part of the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

8187:selp
gene id: 8187:selp
uniprot id: A0A4W6DIA9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:usp48
gene id: 8187:usp48
uniprot id: A0A4W6BWV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

8187:crsp7
gene id: 8187:crsp7
uniprot id: A0A4W6F7S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

8187:bpifcl
gene id: 8187:bpifcl
uniprot id: A0A4W6BLE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

8187:ppfibp1b
gene id: 8187:ppfibp1b
uniprot id: A0A4W6E5Q8
uniprot id: A0A4W6E9G0
uniprot id: A0A4W6E9P8
uniprot id: A0A4W6E9S2
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

8187:LOC108892909
gene id: 8187:LOC108892909
uniprot id: A0A4W6EK29
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:si:dkey-12e7.4
gene id: 8187:si:dkey-12e7.4
uniprot id: A0A4W6DTX3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:banp
gene id: 8187:banp
uniprot id: A0A4W6EEU0
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

8187:wwox
gene id: 8187:wwox
uniprot id: A0A4W6DSC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Golgi apparatus
messages: Lysosome
messages: Mitochondrion

8187:camk2b1
gene id: 8187:camk2b1
uniprot id: A0A4W6E8V5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8187:aqp8a.2
gene id: 8187:aqp8a.2
uniprot id: A0A4W6GBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8187:sla1a
gene id: 8187:sla1a
uniprot id: A0A4W6CT35
names: Subcellular Location Annotation
messages: Cytoplasm

8187:xrcc6
gene id: 8187:xrcc6
uniprot id: A0A4W6G1X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus

8187:cpsf4
gene id: 8187:cpsf4
uniprot id: A0A4W6DD24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

8187:pde6b
gene id: 8187:pde6b
uniprot id: A0A4W6BZV3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8187:slc52a3
gene id: 8187:slc52a3
uniprot id: A0A4W6EC95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8187:LOC108875198
gene id: 8187:LOC108875198
uniprot id: A0A4W6DYL4
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8187:LOC108898918
gene id: 8187:LOC108898918
uniprot id: A0A4W6FWR1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8187:snx9b
gene id: 8187:snx9b
uniprot id: A0A4W6D3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8187:fli1rs
gene id: 8187:fli1rs
uniprot id: A0A4W6BRL0
uniprot id: A0A4W6BZH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:LOC108892168
gene id: 8187:LOC108892168
uniprot id: A0A4W6DS41
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:slc35e1
gene id: 8187:slc35e1
uniprot id: A0A4W6CHD2
names: Subcellular Location Annotation
messages: Membrane

8187:ywhag1
gene id: 8187:ywhag1
uniprot id: A0A4W6ELF2
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8187:LOC108877119
gene id: 8187:LOC108877119
uniprot id: A0A4W6BSG9
names: Similarity
messages: Belongs to the peptidase C2 family.

8187:fgd4a
gene id: 8187:fgd4a
uniprot id: A0A4W6BRS3
uniprot id: A0A4W6BWP0
uniprot id: A0A4W6BZE5
uniprot id: A0A4W6BZR1
names: Subcellular Location Annotation
messages: cytoskeleton

8187:xpa
gene id: 8187:xpa
uniprot id: A0A4W6D3M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

8187:mdm2
gene id: 8187:mdm2
uniprot id: A0A4W6BVP5
uniprot id: A0A4W6CP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Nucleus

8187:intu
gene id: 8187:intu
uniprot id: A0A4W6D8W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

8187:LOC108873989
gene id: 8187:LOC108873989
uniprot id: A0A4W6CIE8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

8187:arhgef6
gene id: 8187:arhgef6
uniprot id: A0A4W6EA31
names: Subcellular Location Annotation
messages: lamellipodium

8187:slc6a1l
gene id: 8187:slc6a1l
uniprot id: A0A4W6C307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8187:LOC108885633
gene id: 8187:LOC108885633
uniprot id: A0A4W6FB56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

8187:slc20a2
gene id: 8187:slc20a2
uniprot id: A0A4W6BRC9
uniprot id: A0A4W6BS16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

8187:sh3bp5b
gene id: 8187:sh3bp5b
uniprot id: A0A4W6BID6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8187:lef1
gene id: 8187:lef1
uniprot id: A0A4W6CA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8187:crbn
gene id: 8187:crbn
uniprot id: A0A4W6EIE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

8187:capza1a
gene id: 8187:capza1a
uniprot id: A0A4W6EJC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8187:stim1a
gene id: 8187:stim1a
uniprot id: A0A4W6DVP6
names: Subcellular Location Annotation
messages: Membrane

8187:msh4
gene id: 8187:msh4
uniprot id: A0A4W6F6L3
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

8187:LOC108892919
gene id: 8187:LOC108892919
uniprot id: A0A4W6EUY1
names: Similarity
messages: Belongs to the IUNH family.

8187:calcrla
gene id: 8187:calcrla
uniprot id: A0A4W6CZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8187:LOC108876707
gene id: 8187:LOC108876707
uniprot id: A0A4W6CSH7
names: Subcellular Location Annotation
messages: Nucleus

8187:rxfp3.2b
gene id: 8187:rxfp3.2b
uniprot id: A0A4W6BYV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:ugdh
gene id: 8187:ugdh
uniprot id: A0A4W6BNL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

8187:LOC108891839
gene id: 8187:LOC108891839
uniprot id: A0A4W6DR33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:tmem165
gene id: 8187:tmem165
uniprot id: A0A4W6CE97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:hpda
gene id: 8187:hpda
uniprot id: A0A4W6EL05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8187:LOC108876515
gene id: 8187:LOC108876515
uniprot id: A0A4W6ETU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8187:foxj2
gene id: 8187:foxj2
uniprot id: A0A4W6D8Q4
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108900201
gene id: 8187:LOC108900201
uniprot id: A0A4W6EU40
uniprot id: A0A4W6EVV1
names: Similarity
messages: Belongs to the SS18 family.

8187:ccn2a
gene id: 8187:ccn2a
uniprot id: A0A4W6EVP2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:fez2b
gene id: 8187:fez2b
uniprot id: A0A4W6EK99
uniprot id: A0A4W6ELB2
uniprot id: A0A4W6EM12
names: Similarity
messages: Belongs to the zygin family.

8187:ube2e2
gene id: 8187:ube2e2
uniprot id: A0A4W6G4P9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:dhps
gene id: 8187:dhps
uniprot id: A0A4W6DZF3
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

8187:avpr1aa
gene id: 8187:avpr1aa
uniprot id: A0A4W6CQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8187:gins2
gene id: 8187:gins2
uniprot id: A0A4W6C9L8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

8187:slc11a2
gene id: 8187:slc11a2
uniprot id: A0A4W6FX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8187:tfip11
gene id: 8187:tfip11
uniprot id: A0A4W6GAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
messages: Nucleus

8187:fam168a
gene id: 8187:fam168a
uniprot id: A0A4W6BSB4
names: Similarity
messages: Belongs to the FAM168 family.

8187:asic1c
gene id: 8187:asic1c
uniprot id: A0A4W6C8G1
uniprot id: A0A4W6C8G8
uniprot id: A0A4W6CFR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108880247
gene id: 8187:LOC108880247
uniprot id: A0A4W6DX54
uniprot id: A0A4W6DXE4
uniprot id: A0A4W6DXU9
uniprot id: A0A4W6DXV4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8187:LOC108889231
gene id: 8187:LOC108889231
uniprot id: A0A4W6G6Z1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8187:hacd4
gene id: 8187:hacd4
uniprot id: A0A4W6F6Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108883421
gene id: 8187:LOC108883421
uniprot id: A0A4W6D8I7
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:LOC108877927
gene id: 8187:LOC108877927
uniprot id: A0A4W6EQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:xkr4
gene id: 8187:xkr4
uniprot id: A0A4W6DXV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8187:LOC108897049
gene id: 8187:LOC108897049
uniprot id: A0A4W6EAL1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8187:dok6
gene id: 8187:dok6
uniprot id: A0A4W6E4N2
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

8187:LOC108879472
gene id: 8187:LOC108879472
uniprot id: A0A4W6C7M4
uniprot id: A0A4W6C8H2
uniprot id: A0A4W6CET0
uniprot id: A0A4W6CGL7
names: Subcellular Location Annotation
messages: Nucleus

8187:lgi3
gene id: 8187:lgi3
uniprot id: A0A4W6FHE2
names: Subcellular Location Annotation
messages: Secreted

8187:LOC108896602
gene id: 8187:LOC108896602
uniprot id: A0A4W6CTA6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

8187:primpol
gene id: 8187:primpol
uniprot id: A0A4W6C0H0
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

8187:LOC108875579
gene id: 8187:LOC108875579
uniprot id: A0A4W6BL78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8187:LOC108892036
gene id: 8187:LOC108892036
uniprot id: A0A4W6DQF0
names: Subcellular Location Annotation
messages: Membrane

8187:tbc1d24
gene id: 8187:tbc1d24
uniprot id: A0A4W6BN46
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse

8187:aig1
gene id: 8187:aig1
uniprot id: A0A4W6F6I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

8187:gys1
gene id: 8187:gys1
uniprot id: A0A4W6BK11
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

8187:LOC108896208
gene id: 8187:LOC108896208
uniprot id: A0A4W6CDX4
names: Similarity
messages: Belongs to the arrestin family.

8187:cnp
gene id: 8187:cnp
uniprot id: A0A4W6CU94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: Melanosome
messages: Membrane

8187:slc9a1a
gene id: 8187:slc9a1a
uniprot id: A0A4W6C6P5
uniprot id: A0A4W6C8F4
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

8187:LOC108897818
gene id: 8187:LOC108897818
uniprot id: A0A4W6D629
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

8187:LOC108877990
gene id: 8187:LOC108877990
uniprot id: A0A4W6GBN8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:adgra3
gene id: 8187:adgra3
uniprot id: A0A4W6EGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

8187:zw10
gene id: 8187:zw10
uniprot id: A0A4W6DEQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

8187:LOC108893579
gene id: 8187:LOC108893579
uniprot id: A0A4W6CSR3
uniprot id: A0A4W6CT82
names: Subcellular Location Annotation
messages: Nucleus

8187:frem2a
gene id: 8187:frem2a
uniprot id: A0A4W6FS27
names: Similarity
messages: Belongs to the FRAS1 family.

8187:LOC108893735
gene id: 8187:LOC108893735
uniprot id: A0A4W6FHB9
names: Similarity
messages: Belongs to the TAFA family.

8187:smpdl3a
gene id: 8187:smpdl3a
uniprot id: A0A4W6F8M0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

8187:pnn
gene id: 8187:pnn
uniprot id: A0A4W6FLH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

8187:LOC108882374
gene id: 8187:LOC108882374
uniprot id: A0A4W6FFV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8187:itgb6
gene id: 8187:itgb6
uniprot id: A0A4W6CWI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

8187:fam171a1
gene id: 8187:fam171a1
uniprot id: A0A4W6CC11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8187:etsrp
gene id: 8187:etsrp
uniprot id: A0A4W6BWJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:pcna
gene id: 8187:pcna
uniprot id: A0A4W6C885
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

8187:LOC108877565
gene id: 8187:LOC108877565
uniprot id: A0A4W6DKK0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108883916
gene id: 8187:LOC108883916
uniprot id: A0A4W6CHU1
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8187:tyk2
gene id: 8187:tyk2
uniprot id: A0A4W6C123
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

8187:cntn4
gene id: 8187:cntn4
uniprot id: A0A4W6FM37
names: Subcellular Location Annotation
messages: Membrane

8187:fign
gene id: 8187:fign
uniprot id: A0A4W6FZX4
names: Similarity
messages: Belongs to the AAA ATPase family.

8187:mffa
gene id: 8187:mffa
uniprot id: A0A4W6E6N1
uniprot id: A0A4W6E7K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

8187:LOC108901758
gene id: 8187:LOC108901758
uniprot id: A0A4W6D258
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:LOC108897740
gene id: 8187:LOC108897740
uniprot id: A0A4W6G6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

8187:cntnap1
gene id: 8187:cntnap1
uniprot id: A0A4W6CQY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

8187:dvl2
gene id: 8187:dvl2
uniprot id: A0A4W6EFU1
names: Similarity
messages: Belongs to the DSH family.

8187:itgb5
gene id: 8187:itgb5
uniprot id: A0A4W6F185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

8187:LOC108883822
gene id: 8187:LOC108883822
uniprot id: A0A4W6BQE9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8187:gabarapa
gene id: 8187:gabarapa
uniprot id: A0A4W6CTR5
names: Similarity
messages: Belongs to the ATG8 family.

8187:hdhd2
gene id: 8187:hdhd2
uniprot id: A0A4W6FVZ4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8187:LOC108881901
gene id: 8187:LOC108881901
uniprot id: A0A4W6F3B2
names: Similarity
messages: Belongs to the MHC class I family.

8187:htr1fa
gene id: 8187:htr1fa
uniprot id: A0A4W6FE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108877587
gene id: 8187:LOC108877587
uniprot id: A0A4W6DMX7
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8187:mtmr11
gene id: 8187:mtmr11
uniprot id: A0A4W6BVP4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8187:LOC108878020
gene id: 8187:LOC108878020
uniprot id: A0A4W6G6M6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8187:LOC108901731
gene id: 8187:LOC108901731
uniprot id: A0A4W6BMK0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

8187:stard13b
gene id: 8187:stard13b
uniprot id: A0A4W6DXK2
uniprot id: A0A4W6DZ05
uniprot id: A0A4W6DZ17
names: Subcellular Location Annotation
messages: Cytoplasm

8187:plpp1a
gene id: 8187:plpp1a
uniprot id: A0A4W6C3S0
uniprot id: A0A4W6C9A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8187:mcee
gene id: 8187:mcee
uniprot id: A0A4W6EVI2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

8187:snrnp27
gene id: 8187:snrnp27
uniprot id: A0A4W6ECL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

8187:serinc4
gene id: 8187:serinc4
uniprot id: A0A4W6BSH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8187:LOC108879744
gene id: 8187:LOC108879744
uniprot id: A0A4W6DS44
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8187:LOC108899918
gene id: 8187:LOC108899918
uniprot id: A0A4W6FLU2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:LOC108883475
gene id: 8187:LOC108883475
uniprot id: A0A4W6DRR9
names: Similarity
messages: Belongs to the Bcl-2 family.

8187:henmt1
gene id: 8187:henmt1
uniprot id: A0A4W6F7Y3
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

8187:ints11
gene id: 8187:ints11
uniprot id: A0A4W6FNA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

8187:LOC108893933
gene id: 8187:LOC108893933
uniprot id: A0A4W6BUE7
names: Subcellular Location Annotation
messages: Nucleus

8187:pdcd10b
gene id: 8187:pdcd10b
uniprot id: A0A4W6E1P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8187:poc5
gene id: 8187:poc5
uniprot id: A0A4W6G9M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

8187:ptger4b
gene id: 8187:ptger4b
uniprot id: A0A4W6BLL9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

8187:rpl19
gene id: 8187:rpl19
uniprot id: A0A4W6FJR0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

8187:ergic3
gene id: 8187:ergic3
uniprot id: A0A4W6FH50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8187:tubb4bl
gene id: 8187:tubb4bl
uniprot id: A0A4W6G029
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8187:LOC108883647
gene id: 8187:LOC108883647
uniprot id: A0A4W6F6X7
names: Similarity
messages: Belongs to the SPSB family.

8187:crot
gene id: 8187:crot
uniprot id: A0A4W6C981
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8187:mpp2b
gene id: 8187:mpp2b
uniprot id: A0A4W6DGE2
uniprot id: A0A4W6DGW1
names: Similarity
messages: Belongs to the MAGUK family.

8187:atp11c
gene id: 8187:atp11c
uniprot id: A0A4W6EIK7
uniprot id: A0A4W6EK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8187:fgf2
gene id: 8187:fgf2
uniprot id: A0A4W6BP40
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:chrm5b
gene id: 8187:chrm5b
uniprot id: A0A4W6FVV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8187:LOC108880450
gene id: 8187:LOC108880450
uniprot id: A0A4W6FCQ1
uniprot id: A0A4W6FDH3
uniprot id: A0A4W6FE99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8187:tsn
gene id: 8187:tsn
uniprot id: A0A4W6EM27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

8187:zgc:113278
gene id: 8187:zgc:113278
uniprot id: A0A4W6ETY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

8187:fitm2
gene id: 8187:fitm2
uniprot id: A0A4W6D2Z0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108895726
gene id: 8187:LOC108895726
uniprot id: A0A4W6BM16
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:ndufc1
gene id: 8187:ndufc1
uniprot id: A0A4W6DSR5
names: Similarity
names: Subunit
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.

8187:slc26a10
gene id: 8187:slc26a10
uniprot id: A0A4W6F822
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8187:ccdc107
gene id: 8187:ccdc107
uniprot id: A0A4W6E6T7
names: Similarity
messages: Belongs to the ric-3 family.

8187:fgf12a
gene id: 8187:fgf12a
uniprot id: A0A4W6E0W7
uniprot id: A0A4W6E4E6
uniprot id: A0A4W6E4Y8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:ddx56
gene id: 8187:ddx56
uniprot id: A0A4W6F2D9
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8187:LOC108893587
gene id: 8187:LOC108893587
uniprot id: A0A4W6BNN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8187:flcn
gene id: 8187:flcn
uniprot id: A0A4W6D3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

8187:cdk5r2b
gene id: 8187:cdk5r2b
uniprot id: A0A4W6G7V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Membrane

8187:ptger2a
gene id: 8187:ptger2a
uniprot id: A0A4W6E2V3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:acvrl1
gene id: 8187:acvrl1
uniprot id: A0A4W6F876
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8187:irx1a
gene id: 8187:irx1a
uniprot id: A0A4W6ES50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8187:dnaja1
gene id: 8187:dnaja1
uniprot id: A0A4W6C195
names: Subcellular Location Annotation
messages: Membrane

8187:ada2a
gene id: 8187:ada2a
uniprot id: A0A4W6BU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

8187:mrpl34
gene id: 8187:mrpl34
uniprot id: A0A4W6FD62
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

8187:slc30a1a
gene id: 8187:slc30a1a
uniprot id: A0A4W6F338
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8187:fabp4a
gene id: 8187:fabp4a
uniprot id: A0A4W6DZ91
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8187:purbb
gene id: 8187:purbb
uniprot id: A0A4W6ERW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

8187:odc1
gene id: 8187:odc1
uniprot id: A0A4W6CID1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

8187:nos1
gene id: 8187:nos1
uniprot id: A0A4W6EDM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

8187:grm6a
gene id: 8187:grm6a
uniprot id: A0A4W6EM09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8187:dynlt2b
gene id: 8187:dynlt2b
uniprot id: A0A4W6D8Z8
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8187:rps27.1
gene id: 8187:rps27.1
uniprot id: A0A4W6FB91
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8187:cmc2
gene id: 8187:cmc2
uniprot id: A0A4W6C9Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

8187:LOC108897122
gene id: 8187:LOC108897122
uniprot id: A0A4W6EK22
names: Similarity
messages: Belongs to the FAM124 family.

8187:lg5h19orf53
gene id: 8187:lg5h19orf53
uniprot id: A0A4W6CCD1
names: Similarity
messages: Belongs to the UPF0390 family.

8187:zgc:158868
gene id: 8187:zgc:158868
uniprot id: A0A4W6FRJ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:chek1
gene id: 8187:chek1
uniprot id: A0A4W6D5T9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

8187:mrpl11
gene id: 8187:mrpl11
uniprot id: A0A4W6EWN4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

8187:rab38a
gene id: 8187:rab38a
uniprot id: A0A4W6F7Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8187:rrad
gene id: 8187:rrad
uniprot id: A0A4W6CFU9
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8187:pfkfb3
gene id: 8187:pfkfb3
uniprot id: A0A4W6F856
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8187:LOC108893993
gene id: 8187:LOC108893993
uniprot id: A0A4W6FJM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8187:LOC108880441
gene id: 8187:LOC108880441
uniprot id: A0A4W6E0B7
names: Subcellular Location Annotation
messages: Cytoplasm

8187:lrp5
gene id: 8187:lrp5
uniprot id: A0A4W6FX23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:septin9b
gene id: 8187:septin9b
uniprot id: A0A4W6FSE4
uniprot id: A0A4W6FSE9
uniprot id: A0A4W6FSH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

8187:ntsr1
gene id: 8187:ntsr1
uniprot id: A0A4W6BL89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:tert
gene id: 8187:tert
uniprot id: A0A4W6FS77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

8187:pgap6
gene id: 8187:pgap6
uniprot id: A0A4W6BT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

8187:ak3
gene id: 8187:ak3
uniprot id: A0A4W6C5X8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

8187:armc1
gene id: 8187:armc1
uniprot id: A0A4W6DRN4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8187:tmed10
gene id: 8187:tmed10
uniprot id: A0A4W6CZB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:kmt5aa
gene id: 8187:kmt5aa
uniprot id: A0A4W6DA59
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8187:si:dkey-202e22.2
gene id: 8187:si:dkey-202e22.2
uniprot id: A0A4W6FAE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:mrps27
gene id: 8187:mrps27
uniprot id: A0A4W6CCE9
names: Subcellular Location Annotation
messages: Mitochondrion

8187:atp6v1h
gene id: 8187:atp6v1h
uniprot id: A0A4W6F4M8
uniprot id: A0A4W6F4N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8187:prkaa2
gene id: 8187:prkaa2
uniprot id: A0A4W6CUD2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

8187:casp9
gene id: 8187:casp9
uniprot id: A0A4W6G7F1
names: Similarity
messages: Belongs to the peptidase C14A family.

8187:hip1rb
gene id: 8187:hip1rb
uniprot id: A0A4W6GBP0
names: Similarity
messages: Belongs to the SLA2 family.

8187:zftraf1
gene id: 8187:zftraf1
uniprot id: A0A4W6CXQ3
names: Similarity
messages: Belongs to the ZFTRAF1 family.

8187:shox
gene id: 8187:shox
uniprot id: A0A4W6DF02
names: Subcellular Location Annotation
messages: Nucleus

8187:cd28
gene id: 8187:cd28
uniprot id: A0A4W6DFC0
names: Subcellular Location Annotation
messages: Membrane

8187:dpy19l1l
gene id: 8187:dpy19l1l
uniprot id: A0A4W6CHN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

8187:slc39a1
gene id: 8187:slc39a1
uniprot id: A0A4W6BMU9
names: Subcellular Location Annotation
messages: Membrane

8187:ghrhrl
gene id: 8187:ghrhrl
uniprot id: A0A4W6DHX6
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108884556
gene id: 8187:LOC108884556
uniprot id: A0A4W6DCM9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:rab18a
gene id: 8187:rab18a
uniprot id: A0A4W6G7S0
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

8187:antxr1c
gene id: 8187:antxr1c
uniprot id: A0A4W6FDA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8187:LOC108883004
gene id: 8187:LOC108883004
uniprot id: A0A4W6C028
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8187:LOC108890799
gene id: 8187:LOC108890799
uniprot id: A0A4W6EV39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

8187:LOC108902667
gene id: 8187:LOC108902667
uniprot id: A0A4W6G1Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

8187:usp33
gene id: 8187:usp33
uniprot id: A0A4W6FVD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

8187:rusf1
gene id: 8187:rusf1
uniprot id: A0A4W6CJQ6
names: Similarity
messages: Belongs to the RUS1 family.

8187:LOC108892041
gene id: 8187:LOC108892041
uniprot id: A0A4W6E668
names: Subcellular Location Annotation
messages: ruffle membrane

8187:apoda.1
gene id: 8187:apoda.1
uniprot id: A0A4W6E709
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8187:LOC108889856
gene id: 8187:LOC108889856
uniprot id: A0A4W6EZ64
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

8187:golph3a
gene id: 8187:golph3a
uniprot id: A0A4W6E6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

8187:LOC108903070
gene id: 8187:LOC108903070
uniprot id: A0A4W6D256
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

8187:tcea1
gene id: 8187:tcea1
uniprot id: A0A4W6F5L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

8187:dsc2l
gene id: 8187:dsc2l
uniprot id: A0A4W6DBL7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

8187:psme3ip1
gene id: 8187:psme3ip1
uniprot id: A0A4W6DJT5
names: Subcellular Location Annotation
messages: Nucleus

8187:tmem86b
gene id: 8187:tmem86b
uniprot id: A0A4W6BK93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

8187:jakmip2
gene id: 8187:jakmip2
uniprot id: A0A4W6EHS8
uniprot id: A0A4W6EHV2
names: Similarity
messages: Belongs to the JAKMIP family.

8187:tmem147
gene id: 8187:tmem147
uniprot id: A0A4W6EFD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM147 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:trappc13
gene id: 8187:trappc13
uniprot id: A0A4W6CKK4
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

8187:psmc4
gene id: 8187:psmc4
uniprot id: A0A4W6BX63
names: Similarity
messages: Belongs to the AAA ATPase family.

8187:avpr2l
gene id: 8187:avpr2l
uniprot id: A0A4W6G1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8187:sptssa
gene id: 8187:sptssa
uniprot id: A0A4W6CGV9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108885583
gene id: 8187:LOC108885583
uniprot id: A0A4W6ESI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8187:LOC108883419
gene id: 8187:LOC108883419
uniprot id: A0A4W6D7Y4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:LOC108887784
gene id: 8187:LOC108887784
uniprot id: A0A4W6EJD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:ippk
gene id: 8187:ippk
uniprot id: A0A4W6C789
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

8187:myf6
gene id: 8187:myf6
uniprot id: A0A4W6BY83
uniprot id: A0A4W6BY87
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8187:ndr2
gene id: 8187:ndr2
uniprot id: A0A4W6EZA0
names: Similarity
messages: Belongs to the TGF-beta family.

8187:mat2ab
gene id: 8187:mat2ab
uniprot id: A0A4W6GB06
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8187:LOC108899295
gene id: 8187:LOC108899295
uniprot id: A0A4W6FF50
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:si:dkey-33c9.6
gene id: 8187:si:dkey-33c9.6
uniprot id: A0A4W6EA59
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

8187:cry1b
gene id: 8187:cry1b
uniprot id: A0A4W6ESA6
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8187:cdc45
gene id: 8187:cdc45
uniprot id: A0A4W6C610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

8187:ano8b
gene id: 8187:ano8b
uniprot id: A0A4W6CRG5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:fbln5
gene id: 8187:fbln5
uniprot id: A0A4W6FE47
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108878309
gene id: 8187:LOC108878309
uniprot id: A0A4W6FQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8187:ube2g1a
gene id: 8187:ube2g1a
uniprot id: A0A4W6EDS8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:LOC108884820
gene id: 8187:LOC108884820
uniprot id: A0A4W6EC38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8187:LOC108879428
gene id: 8187:LOC108879428
uniprot id: A0A4W6DEQ8
uniprot id: A0A4W6DH53
names: Similarity
messages: Belongs to the cornifelin family.

8187:LOC108872754
gene id: 8187:LOC108872754
uniprot id: A0A4W6F8E6
names: Subcellular Location Annotation
messages: Nucleus

8187:apoa1b
gene id: 8187:apoa1b
uniprot id: A0A4W6DST3
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8187:ppm1aa
gene id: 8187:ppm1aa
uniprot id: A0A4W6FL73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8187:lin7c
gene id: 8187:lin7c
uniprot id: A0A4W6ERD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8187:fbxo32
gene id: 8187:fbxo32
uniprot id: A0A4W6EDM2
names: Subcellular Location Annotation
messages: Nucleus

8187:scube3
gene id: 8187:scube3
uniprot id: A0A4W6DCW6
uniprot id: A0A4W6DDF4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:pithd1
gene id: 8187:pithd1
uniprot id: A0A4W6DMG4
names: Similarity
messages: Belongs to the PITHD1 family.

8187:LOC108889278
gene id: 8187:LOC108889278
uniprot id: A0A4W6F403
names: Similarity
messages: Belongs to the DNase I family.

8187:endou2
gene id: 8187:endou2
uniprot id: A0A4W6EWV9
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8187:fbp1b
gene id: 8187:fbp1b
uniprot id: A0A4W6FB48
names: Similarity
messages: Belongs to the FBPase class 1 family.

8187:slc50a1
gene id: 8187:slc50a1
uniprot id: A0A4W6FTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108891664
gene id: 8187:LOC108891664
uniprot id: A0A4W6C1S0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108890038
gene id: 8187:LOC108890038
uniprot id: A0A4W6ELJ9
names: Subcellular Location Annotation
messages: Membrane

8187:msmp2
gene id: 8187:msmp2
uniprot id: A0A4W6BPB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

8187:ntn4
gene id: 8187:ntn4
uniprot id: A0A4W6G2D4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108897530
gene id: 8187:LOC108897530
uniprot id: A0A4W6BX85
uniprot id: A0A4W6C4A1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

8187:aqp12
gene id: 8187:aqp12
uniprot id: A0A4W6CQH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

8187:coq9
gene id: 8187:coq9
uniprot id: A0A4W6CZU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

8187:mos
gene id: 8187:mos
uniprot id: A0A4W6ENR6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:tardbpb
gene id: 8187:tardbpb
uniprot id: A0A4W6CJ32
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108897837
gene id: 8187:LOC108897837
uniprot id: A0A4W6CN37
names: Similarity
messages: Belongs to the IL-6 superfamily.

8187:gad2
gene id: 8187:gad2
uniprot id: A0A4W6DYJ4
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8187:LOC108894681
gene id: 8187:LOC108894681
uniprot id: A0A4W6C0N0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8187:map4k2
gene id: 8187:map4k2
uniprot id: A0A4W6E9K9
uniprot id: A0A4W6EAT9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

8187:lyrm9
gene id: 8187:lyrm9
uniprot id: A0A4W6CLM9
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

8187:mrto4
gene id: 8187:mrto4
uniprot id: A0A4W6F332
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

8187:lrrc4bb
gene id: 8187:lrrc4bb
uniprot id: A0A4W6BJZ3
names: Subcellular Location Annotation
messages: Membrane

8187:cxadr
gene id: 8187:cxadr
uniprot id: A0A4W6E8M5
names: Subcellular Location Annotation
messages: Membrane

8187:ndufs5
gene id: 8187:ndufs5
uniprot id: A0A4W6FB21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

8187:ndfip2
gene id: 8187:ndfip2
uniprot id: A0A4W6FIZ0
names: Subcellular Location Annotation
messages: Membrane

8187:yars2
gene id: 8187:yars2
uniprot id: A0A4W6CWA6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8187:dhrs1
gene id: 8187:dhrs1
uniprot id: A0A4W6CPW1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:LOC108901504
gene id: 8187:LOC108901504
uniprot id: A0A4W6G6C7
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8187:LOC108888881
gene id: 8187:LOC108888881
uniprot id: A0A4W6FC01
names: Similarity
messages: Belongs to the S-100 family.

8187:s100z
gene id: 8187:s100z
uniprot id: A0A4W6DDV1
names: Similarity
messages: Belongs to the S-100 family.

8187:ptp4a1
gene id: 8187:ptp4a1
uniprot id: A0A4W6EXR1
uniprot id: A0A4W6EXS6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8187:sema4bb
gene id: 8187:sema4bb
uniprot id: A0A4W6FKK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:cart2
gene id: 8187:cart2
uniprot id: A0A4W6FDX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8187:fam110d
gene id: 8187:fam110d
uniprot id: A0A4W6BZ29
names: Similarity
messages: Belongs to the FAM110 family.

8187:tmtc4
gene id: 8187:tmtc4
uniprot id: A0A4W6DEN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8187:LOC108884332
gene id: 8187:LOC108884332
uniprot id: A0A4W6BXX7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8187:rab3aa
gene id: 8187:rab3aa
uniprot id: A0A4W6F7K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

8187:LOC108873084
gene id: 8187:LOC108873084
uniprot id: A0A4W6DLW7
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:ltbp1
gene id: 8187:ltbp1
uniprot id: A0A4W6G4L7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:aopep
gene id: 8187:aopep
uniprot id: A0A4W6CBN8
names: Similarity
messages: Belongs to the peptidase M1 family.

8187:LOC108893503
gene id: 8187:LOC108893503
uniprot id: A0A4W6F8N9
uniprot id: A0A4W6FAY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

8187:zgc:173742
gene id: 8187:zgc:173742
uniprot id: A0A4W6DBV6
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

8187:rpl13
gene id: 8187:rpl13
uniprot id: A0A4W6G3F3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

8187:lg17h8orf82
gene id: 8187:lg17h8orf82
uniprot id: A0A4W6F978
names: Similarity
messages: Belongs to the UPF0598 family.

8187:LOC108875184
gene id: 8187:LOC108875184
uniprot id: A0A4W6DNR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8187:shpk
gene id: 8187:shpk
uniprot id: A0A4W6ERZ9
names: Similarity
messages: Belongs to the FGGY kinase family.

8187:egr3
gene id: 8187:egr3
uniprot id: A0A4W6G7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

8187:LOC108901370
gene id: 8187:LOC108901370
uniprot id: A0A4W6DNF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:sigirr
gene id: 8187:sigirr
uniprot id: A0A4W6DBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

8187:atpv0e2
gene id: 8187:atpv0e2
uniprot id: A0A4W6EJJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8187:LOC108884213
gene id: 8187:LOC108884213
uniprot id: A0A4W6F616
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

8187:anapc16
gene id: 8187:anapc16
uniprot id: A0A4W6EWT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

8187:plk4
gene id: 8187:plk4
uniprot id: A0A4W6FA03
names: Subcellular Location Annotation
messages: centriole

8187:si:dkey-51e6.1
gene id: 8187:si:dkey-51e6.1
uniprot id: A0A4W6DIU9
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

8187:nppa
gene id: 8187:nppa
uniprot id: A0A4W6G306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8187:zgc:92907
gene id: 8187:zgc:92907
uniprot id: A0A4W6EW95
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

8187:ppm1kb
gene id: 8187:ppm1kb
uniprot id: A0A4W6BYJ6
names: Similarity
messages: Belongs to the PP2C family.

8187:specc1la
gene id: 8187:specc1la
uniprot id: A0A4W6G9A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

8187:tcp1
gene id: 8187:tcp1
uniprot id: A0A4W6ELU7
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

8187:LOC108884858
gene id: 8187:LOC108884858
uniprot id: A0A4W6EGL6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8187:thop1
gene id: 8187:thop1
uniprot id: A0A4W6DNH0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

8187:pals2a
gene id: 8187:pals2a
uniprot id: A0A4W6DJL3
names: Similarity
messages: Belongs to the MAGUK family.

8187:cers1
gene id: 8187:cers1
uniprot id: A0A4W6FRI4
names: Subcellular Location Annotation
messages: Membrane

8187:ppm1nb
gene id: 8187:ppm1nb
uniprot id: A0A4W6FKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8187:dusp6
gene id: 8187:dusp6
uniprot id: A0A4W6C3R2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8187:dpysl5a
gene id: 8187:dpysl5a
uniprot id: A0A4W6ER39
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8187:efhc1
gene id: 8187:efhc1
uniprot id: A0A4W6ERK8
names: Subcellular Location Annotation
messages: cilium axoneme

8187:arl2bp
gene id: 8187:arl2bp
uniprot id: A0A4W6DDM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
messages: centrosome
messages: cilium basal body

8187:rnf167
gene id: 8187:rnf167
uniprot id: A0A4W6FV80
names: Subcellular Location Annotation
messages: Membrane

8187:nubp1
gene id: 8187:nubp1
uniprot id: A0A4W6C276
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

8187:pgk1
gene id: 8187:pgk1
uniprot id: A0A4W6DLL5
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

8187:gsx2
gene id: 8187:gsx2
uniprot id: A0A4W6CGZ3
names: Subcellular Location Annotation
messages: Nucleus

8187:ube2g1b
gene id: 8187:ube2g1b
uniprot id: A0A4W6DE03
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:sf3b6
gene id: 8187:sf3b6
uniprot id: A0A4W6C6N2
names: Subcellular Location Annotation
messages: Nucleus

8187:pnpla6
gene id: 8187:pnpla6
uniprot id: A0A4W6DAW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:xrcc1
gene id: 8187:xrcc1
uniprot id: A0A4W6BTG9
names: Subcellular Location Annotation
messages: Nucleus

8187:bcr
gene id: 8187:bcr
uniprot id: A0A4W6CM51
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

8187:LOC108890265
gene id: 8187:LOC108890265
uniprot id: A0A4W6FGY5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:LOC108885898
gene id: 8187:LOC108885898
uniprot id: A0A4W6D168
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:gdap2
gene id: 8187:gdap2
uniprot id: A0A4W6G123
names: Similarity
messages: Belongs to the GDAP2 family.

8187:rmi1
gene id: 8187:rmi1
uniprot id: A0A4W6GCS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

8187:cdkal1
gene id: 8187:cdkal1
uniprot id: A0A4W6BYL0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

8187:srms
gene id: 8187:srms
uniprot id: A0A4W6EZX9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8187:LOC108901956
gene id: 8187:LOC108901956
uniprot id: A0A4W6CYS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:ildr1b
gene id: 8187:ildr1b
uniprot id: A0A4W6FJL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8187:LOC108895480
gene id: 8187:LOC108895480
uniprot id: A0A4W6CWZ7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:ntrk3b
gene id: 8187:ntrk3b
uniprot id: A0A4W6G3S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8187:LOC108895647
gene id: 8187:LOC108895647
uniprot id: A0A4W6D1H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8187:LOC108876620
gene id: 8187:LOC108876620
uniprot id: A0A4W6D858
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

8187:sfrp2l
gene id: 8187:sfrp2l
uniprot id: A0A4W6F7T1
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:epn1a
gene id: 8187:epn1a
uniprot id: A0A4W6D808
uniprot id: A0A4W6D8S6
names: Similarity
messages: Belongs to the epsin family.

8187:xylt2
gene id: 8187:xylt2
uniprot id: A0A4W6BUB8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

8187:LOC108883423
gene id: 8187:LOC108883423
uniprot id: A0A4W6D8N0
uniprot id: A0A4W6D8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

8187:med4
gene id: 8187:med4
uniprot id: A0A4W6DDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8187:gba
gene id: 8187:gba
uniprot id: A0A4W6FS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

8187:LOC108880193
gene id: 8187:LOC108880193
uniprot id: A0A4W6DQG4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane

8187:lbx1a
gene id: 8187:lbx1a
uniprot id: A0A4W6DR38
names: Subcellular Location Annotation
messages: Nucleus

8187:fhip1aa
gene id: 8187:fhip1aa
uniprot id: A0A4W6ENK6
names: Similarity
messages: Belongs to the FHIP family.

8187:LOC108891283
gene id: 8187:LOC108891283
uniprot id: A0A4W6FXA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

8187:copz2
gene id: 8187:copz2
uniprot id: A0A4W6C1U0
uniprot id: A0A4W6C1U5
uniprot id: A0A4W6C927
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

8187:serbp1b
gene id: 8187:serbp1b
uniprot id: A0A4W6FND0
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

8187:psma6b
gene id: 8187:psma6b
uniprot id: A0A4W6CCD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8187:adam10a
gene id: 8187:adam10a
uniprot id: A0A4W6E102
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108883461
gene id: 8187:LOC108883461
uniprot id: A0A4W6DNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8187:adam28
gene id: 8187:adam28
uniprot id: A0A4W6G568
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108884963
gene id: 8187:LOC108884963
uniprot id: A0A4W6CNX4
uniprot id: A0A4W6CNY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8187:phf10
gene id: 8187:phf10
uniprot id: A0A4W6G0M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

8187:LOC108900057
gene id: 8187:LOC108900057
uniprot id: A0A4W6DHU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

8187:LOC108886974
gene id: 8187:LOC108886974
uniprot id: A0A4W6FS78
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

8187:ptger1c
gene id: 8187:ptger1c
uniprot id: A0A4W6FR51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108876940
gene id: 8187:LOC108876940
uniprot id: A0A4W6EQ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8187:tprg1l
gene id: 8187:tprg1l
uniprot id: A0A4W6G652
names: Similarity
messages: Belongs to the TPRG1 family.

8187:LOC108889502
gene id: 8187:LOC108889502
uniprot id: A0A4W6ENF6
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

8187:nts
gene id: 8187:nts
uniprot id: A0A4W6FYD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

8187:gtf2h1
gene id: 8187:gtf2h1
uniprot id: A0A4W6E1L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

8187:LOC108875326
gene id: 8187:LOC108875326
uniprot id: A0A4W6CKD0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:apom
gene id: 8187:apom
uniprot id: A0A4W6BQN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

8187:LOC108873033
gene id: 8187:LOC108873033
uniprot id: A0A4W6FF43
names: Subcellular Location Annotation
messages: cytoskeleton

8187:loxl5b
gene id: 8187:loxl5b
uniprot id: A0A4W6EC03
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8187:mogs
gene id: 8187:mogs
uniprot id: A0A4W6C145
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

8187:srrd
gene id: 8187:srrd
uniprot id: A0A4W6GC43
names: Similarity
messages: Belongs to the SRR1 family.

8187:alg11
gene id: 8187:alg11
uniprot id: A0A4W6G5Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

8187:LOC108891882
gene id: 8187:LOC108891882
uniprot id: A0A4W6FH71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:cdc42ep4b
gene id: 8187:cdc42ep4b
uniprot id: A0A4W6E313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8187:iglon5
gene id: 8187:iglon5
uniprot id: A0A4W6BTV3
names: Subcellular Location Annotation
messages: Membrane

8187:tti2
gene id: 8187:tti2
uniprot id: A0A4W6E1A2
names: Similarity
messages: Belongs to the TTI2 family.

8187:phkg1a
gene id: 8187:phkg1a
uniprot id: A0A4W6CR44
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

8187:hspb6
gene id: 8187:hspb6
uniprot id: A0A4W6CYB6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8187:LOC108897882
gene id: 8187:LOC108897882
uniprot id: A0A4W6BQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Membrane
messages: Mitochondrion inner membrane

8187:dynll2b
gene id: 8187:dynll2b
uniprot id: A0A4W6D8T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8187:LOC108893515
gene id: 8187:LOC108893515
uniprot id: A0A4W6FFB5
names: Subcellular Location Annotation
messages: Membrane

8187:acsl2
gene id: 8187:acsl2
uniprot id: A0A4W6G7W2
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8187:atp6v1d
gene id: 8187:atp6v1d
uniprot id: A0A4W6EHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

8187:rdh10a
gene id: 8187:rdh10a
uniprot id: A0A4W6E3J3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:gpcpd1
gene id: 8187:gpcpd1
uniprot id: A0A4W6DZ52
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8187:tpst1l
gene id: 8187:tpst1l
uniprot id: A0A4W6F297
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

8187:kif18a
gene id: 8187:kif18a
uniprot id: A0A4W6ETY5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8187:LOC108895847
gene id: 8187:LOC108895847
uniprot id: A0A4W6CCH8
names: Similarity
messages: Belongs to the serpin family.

8187:spen
gene id: 8187:spen
uniprot id: A0A4W6BKS2
names: Similarity
messages: Belongs to the RRM Spen family.

8187:bco2b
gene id: 8187:bco2b
uniprot id: A0A4W6C416
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8187:zic1
gene id: 8187:zic1
uniprot id: A0A4W6D910
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8187:LOC108892607
gene id: 8187:LOC108892607
uniprot id: A0A4W6D4X8
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

8187:glula
gene id: 8187:glula
uniprot id: A0A4W6DJL9
names: Similarity
messages: Belongs to the glutamine synthetase family.

8187:lmf1
gene id: 8187:lmf1
uniprot id: A0A4W6EDX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

8187:pcyox1
gene id: 8187:pcyox1
uniprot id: A0A4W6C120
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

8187:pik3cg
gene id: 8187:pik3cg
uniprot id: A0A4W6FZK7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8187:LOC108878076
gene id: 8187:LOC108878076
uniprot id: A0A4W6F4T2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8187:thbs2a
gene id: 8187:thbs2a
uniprot id: A0A4W6EDJ8
uniprot id: A0A4W6EDL1
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108878384
gene id: 8187:LOC108878384
uniprot id: A0A4W6G452
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8187:LOC108872926
gene id: 8187:LOC108872926
uniprot id: A0A4W6C242
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8187:entpd3
gene id: 8187:entpd3
uniprot id: A0A4W6EIR1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8187:lg6h1orf174
gene id: 8187:lg6h1orf174
uniprot id: A0A4W6G8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

8187:slc25a15b
gene id: 8187:slc25a15b
uniprot id: A0A4W6BRF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:fap
gene id: 8187:fap
uniprot id: A0A4W6FYH7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

8187:paxbp1
gene id: 8187:paxbp1
uniprot id: A0A4W6DBF1
names: Similarity
messages: Belongs to the GCF family.

8187:LOC108887823
gene id: 8187:LOC108887823
uniprot id: A0A4W6ETD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:ppm1e
gene id: 8187:ppm1e
uniprot id: A0A4W6DJU2
names: Similarity
messages: Belongs to the PP2C family.

8187:LOC108879067
gene id: 8187:LOC108879067
uniprot id: A0A4W6D424
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:zdhhc16b
gene id: 8187:zdhhc16b
uniprot id: A0A4W6FA07
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8187:impdh1b
gene id: 8187:impdh1b
uniprot id: A0A4W6E7N1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

8187:LOC108883895
gene id: 8187:LOC108883895
uniprot id: A0A4W6CBV3
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

8187:fzr1b
gene id: 8187:fzr1b
uniprot id: A0A4W6BPZ3
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8187:ano5b
gene id: 8187:ano5b
uniprot id: A0A4W6F0I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

8187:map7d3
gene id: 8187:map7d3
uniprot id: A0A4W6EBA3
uniprot id: A0A4W6EBA8
uniprot id: A0A4W6EBC1
names: Similarity
messages: Belongs to the MAP7 family.

8187:cxxc5a
gene id: 8187:cxxc5a
uniprot id: A0A4W6D106
uniprot id: A0A4W6D1K2
names: Subcellular Location Annotation
messages: Cytoplasm

8187:LOC108900626
gene id: 8187:LOC108900626
uniprot id: A0A4W6CNW9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:chst3a
gene id: 8187:chst3a
uniprot id: A0A4W6E6L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8187:pdyn
gene id: 8187:pdyn
uniprot id: A0A4W6E7R3
names: Similarity
messages: Belongs to the opioid neuropeptide precursor family.

8187:cacng2a
gene id: 8187:cacng2a
uniprot id: A0A4W6DZY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

8187:zgc:154142
gene id: 8187:zgc:154142
uniprot id: A0A4W6BY19
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8187:LOC108876370
gene id: 8187:LOC108876370
uniprot id: A0A4W6C5Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

8187:LOC108877312
gene id: 8187:LOC108877312
uniprot id: A0A4W6BYE9
names: Subcellular Location Annotation
messages: extracellular space

8187:eif4e3
gene id: 8187:eif4e3
uniprot id: A0A4W6FWK6
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8187:LOC108873407
gene id: 8187:LOC108873407
uniprot id: A0A4W6BQR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:LOC108902695
gene id: 8187:LOC108902695
uniprot id: A0A4W6G003
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

8187:ctbp2a
gene id: 8187:ctbp2a
uniprot id: A0A4W6DMU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8187:lin28aa
gene id: 8187:lin28aa
uniprot id: A0A4W6DHA3
names: Similarity
messages: Belongs to the lin-28 family.

8187:si:ch211-225p5.8
gene id: 8187:si:ch211-225p5.8
uniprot id: A0A4W6BRR7
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108890270
gene id: 8187:LOC108890270
uniprot id: A0A4W6CS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8187:b3gnt7
gene id: 8187:b3gnt7
uniprot id: A0A4W6D8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:rrp15
gene id: 8187:rrp15
uniprot id: A0A4W6C6D8
names: Similarity
messages: Belongs to the RRP15 family.

8187:emp3a
gene id: 8187:emp3a
uniprot id: A0A4W6FL55
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108879841
gene id: 8187:LOC108879841
uniprot id: A0A4W6CQ23
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108880716
gene id: 8187:LOC108880716
uniprot id: A0A4W6BNW0
names: Subcellular Location Annotation
messages: extracellular space

8187:ptk7b
gene id: 8187:ptk7b
uniprot id: A0A4W6C6W4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:th
gene id: 8187:th
uniprot id: A0A4W6ELK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

8187:slc4a4a
gene id: 8187:slc4a4a
uniprot id: A0A4W6FQZ7
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

8187:scpep1
gene id: 8187:scpep1
uniprot id: A0A4W6CU04
uniprot id: A0A4W6EZ73
names: Similarity
messages: Belongs to the peptidase S10 family.

8187:fam163ba
gene id: 8187:fam163ba
uniprot id: A0A4W6C2W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8187:arid3a
gene id: 8187:arid3a
uniprot id: A0A4W6D918
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

8187:plk2b
gene id: 8187:plk2b
uniprot id: A0A4W6BWU1
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

8187:kdm7aa
gene id: 8187:kdm7aa
uniprot id: A0A4W6BZ81
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8187:marcksl1b
gene id: 8187:marcksl1b
uniprot id: A0A4W6CEE2
names: Similarity
messages: Belongs to the MARCKS family.

8187:LOC108891677
gene id: 8187:LOC108891677
uniprot id: A0A4W6BLV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:hapln2
gene id: 8187:hapln2
uniprot id: A0A4W6D3X2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108883750
gene id: 8187:LOC108883750
uniprot id: A0A4W6FJK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8187:mtx1a
gene id: 8187:mtx1a
uniprot id: A0A4W6DSJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

8187:st3gal4
gene id: 8187:st3gal4
uniprot id: A0A4W6CVC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8187:slc35b4
gene id: 8187:slc35b4
uniprot id: A0A4W6F4X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8187:LOC108878169
gene id: 8187:LOC108878169
uniprot id: A0A4W6GB40
names: Similarity
messages: Belongs to the LIX1 family.

8187:drd4b
gene id: 8187:drd4b
uniprot id: A0A4W6C5I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:plppr5b
gene id: 8187:plppr5b
uniprot id: A0A4W6ENU9
uniprot id: A0A4W6EQV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8187:pklr
gene id: 8187:pklr
uniprot id: A0A4W6FQ72
names: Similarity
messages: Belongs to the pyruvate kinase family.

8187:ap1s1
gene id: 8187:ap1s1
uniprot id: A0A4W6ECQ1
uniprot id: A0A4W6EHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8187:metap2a
gene id: 8187:metap2a
uniprot id: A0A4W6G3N4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

8187:mb
gene id: 8187:mb
uniprot id: A0A4W6FXS8
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

8187:tomm20a
gene id: 8187:tomm20a
uniprot id: A0A4W6CJF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

8187:sema3c
gene id: 8187:sema3c
uniprot id: A0A4W6BYW5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:smad2
gene id: 8187:smad2
uniprot id: A0A4W6G958
uniprot id: A0A4W6GA18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108887813
gene id: 8187:LOC108887813
uniprot id: A0A4W6E8W4
uniprot id: G9BD44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8187:gorasp1a
gene id: 8187:gorasp1a
uniprot id: A0A4W6CGT0
names: Similarity
messages: Belongs to the GORASP family.

8187:smarca2
gene id: 8187:smarca2
uniprot id: A0A4W6FJ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8187:LOC108886642
gene id: 8187:LOC108886642
uniprot id: A0A4W6DHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8187:LOC108878490
gene id: 8187:LOC108878490
uniprot id: A0A4W6E5I9
names: Similarity
messages: Belongs to the YOS1 family.

8187:anxa3b
gene id: 8187:anxa3b
uniprot id: A0A4W6CDD9
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8187:bzw1a
gene id: 8187:bzw1a
uniprot id: A0A4W6EVJ3
names: Similarity
messages: Belongs to the BZW family.

8187:bhmt
gene id: 8187:bhmt
uniprot id: A0A4W6CX23
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8187:creb1b
gene id: 8187:creb1b
uniprot id: A0A4W6DIA7
names: Subcellular Location Annotation
messages: Nucleus

8187:ephb4a
gene id: 8187:ephb4a
uniprot id: A0A4W6CMZ8
names: Subcellular Location Annotation
messages: Membrane

8187:lg20h5orf24
gene id: 8187:lg20h5orf24
uniprot id: A0A4W6DNW7
names: Similarity
messages: Belongs to the UPF0461 family.

8187:tmem63ba
gene id: 8187:tmem63ba
uniprot id: A0A4W6BQP8
uniprot id: A0A4W6BYH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

8187:LOC108896262
gene id: 8187:LOC108896262
uniprot id: A0A4W6EYX1
names: Subcellular Location Annotation
messages: Membrane

8187:hddc2
gene id: 8187:hddc2
uniprot id: A0A4W6EN93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

8187:prss16
gene id: 8187:prss16
uniprot id: A0A4W6C476
names: Similarity
messages: Belongs to the peptidase S28 family.

8187:LOC108902772
gene id: 8187:LOC108902772
uniprot id: A0A4W6E2U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

8187:hbae5
gene id: 8187:hbae5
uniprot id: A0A4W6GAD4
names: Similarity
messages: Belongs to the globin family.

8187:carnmt1
gene id: 8187:carnmt1
uniprot id: A0A4W6FTT8
names: Similarity
messages: Belongs to the carnosine N-methyltransferase family.

8187:ptpn2b
gene id: 8187:ptpn2b
uniprot id: A0A4W6DXG2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8187:si:dkey-202l22.3
gene id: 8187:si:dkey-202l22.3
uniprot id: A0A4W6ELW0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:fgfr4
gene id: 8187:fgfr4
uniprot id: A0A4W6DKP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:nucb2a
gene id: 8187:nucb2a
uniprot id: A0A4W6FC29
names: Similarity
messages: Belongs to the nucleobindin family.

8187:LOC108882133
gene id: 8187:LOC108882133
uniprot id: A0A4W6DFQ7
names: Similarity
messages: Belongs to the TAFA family.

8187:fip1l1b
gene id: 8187:fip1l1b
uniprot id: A0A4W6G6M5
uniprot id: A0A4W6G8X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

8187:snx33
gene id: 8187:snx33
uniprot id: A0A4W6CNW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8187:nap1l4a
gene id: 8187:nap1l4a
uniprot id: A0A4W6EI81
uniprot id: A0A4W6EML1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8187:LOC108873086
gene id: 8187:LOC108873086
uniprot id: A0A4W6DIS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8187:LOC108889373
gene id: 8187:LOC108889373
uniprot id: A0A4W6BVZ5
names: Subcellular Location Annotation
messages: Cytoplasm

8187:mcoln2
gene id: 8187:mcoln2
uniprot id: A0A4W6FC14
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8187:apex2
gene id: 8187:apex2
uniprot id: A0A4W6DPU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

8187:fgf7
gene id: 8187:fgf7
uniprot id: A0A4W6BR48
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:krtcap2
gene id: 8187:krtcap2
uniprot id: A0A4W6FV91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

8187:kdm5ba
gene id: 8187:kdm5ba
uniprot id: A0A4W6FWV4
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

8187:cdc6
gene id: 8187:cdc6
uniprot id: A0A4W6G988
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

8187:mlst8
gene id: 8187:mlst8
uniprot id: A0A4W6G9V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of TORC1 complex. Part of the TORC2 complex.
messages: Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.

8187:smoc1
gene id: 8187:smoc1
uniprot id: A0A4W6BMW6
uniprot id: A0A4W6BMW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:nkx2.9
gene id: 8187:nkx2.9
uniprot id: A0A4W6BTI9
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108900219
gene id: 8187:LOC108900219
uniprot id: A0A4W6ET51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8187:mrps9
gene id: 8187:mrps9
uniprot id: A0A4W6D7U0
uniprot id: A0A4W6D7U7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8187:b4galt2
gene id: 8187:b4galt2
uniprot id: A0A4W6BQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8187:slc26a1
gene id: 8187:slc26a1
uniprot id: A0A4W6BN38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sodium-independent sulfate anion transporter. Can transport other anions including bicarbonate, thiosulfate and oxalate.

8187:mab21l2
gene id: 8187:mab21l2
uniprot id: A0A4W6ES85
names: Similarity
messages: Belongs to the mab-21 family.

8187:etfa
gene id: 8187:etfa
uniprot id: A0A4W6CG56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

8187:LOC108901983
gene id: 8187:LOC108901983
uniprot id: A0A4W6D1B4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:cplx4a
gene id: 8187:cplx4a
uniprot id: A0A4W6C7L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8187:LOC108877301
gene id: 8187:LOC108877301
uniprot id: A0A4W6BXI8
names: Subcellular Location Annotation
messages: extracellular space

8187:fibinb
gene id: 8187:fibinb
uniprot id: A0A4W6ERY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

8187:cnrip1a
gene id: 8187:cnrip1a
uniprot id: A0A4W6DME4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

8187:slc25a26
gene id: 8187:slc25a26
uniprot id: A0A4W6FDX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:rag1
gene id: 8187:rag1
uniprot id: A0A4W6EH50
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

8187:iah1
gene id: 8187:iah1
uniprot id: A0A4W6FE18
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

8187:mcm2
gene id: 8187:mcm2
uniprot id: A0A4W6DHG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8187:adamts6
gene id: 8187:adamts6
uniprot id: A0A4W6CDL9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:ppardb
gene id: 8187:ppardb
uniprot id: A0A4W6CST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:ndufb3
gene id: 8187:ndufb3
uniprot id: A0A4W6C589
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

8187:sema4c
gene id: 8187:sema4c
uniprot id: A0A4W6EPM8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:pomk
gene id: 8187:pomk
uniprot id: A0A4W6ELB8
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

8187:zgc:158403
gene id: 8187:zgc:158403
uniprot id: A0A4W6E7Y9
names: Similarity
messages: Belongs to the TTC39 family.

8187:LOC108886515
gene id: 8187:LOC108886515
uniprot id: A0A4W6EP42
names: Subcellular Location Annotation
messages: Nucleus

8187:ids
gene id: 8187:ids
uniprot id: A0A4W6FVC5
uniprot id: A0A4W6FVC9
names: Similarity
messages: Belongs to the sulfatase family.

8187:LOC108882586
gene id: 8187:LOC108882586
uniprot id: A0A4W6BK47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:wnt4
gene id: 8187:wnt4
uniprot id: A0A4W6FGQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:aif1l
gene id: 8187:aif1l
uniprot id: A0A4W6BQG4
names: Subcellular Location Annotation
messages: ruffle membrane

8187:tmco1
gene id: 8187:tmco1
uniprot id: A0A4W6CUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:rflnb
gene id: 8187:rflnb
uniprot id: A0A4W6D2I4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8187:LOC108887833
gene id: 8187:LOC108887833
uniprot id: A0A4W6EPA5
uniprot id: A0A4W6ESQ6
names: Subcellular Location Annotation
messages: Cytoplasm

8187:f3a
gene id: 8187:f3a
uniprot id: A0A4W6ET80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

8187:prdm2b
gene id: 8187:prdm2b
uniprot id: A0A4W6FKU8
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108900795
gene id: 8187:LOC108900795
uniprot id: A0A4W6CPS6
names: Similarity
messages: Belongs to the Bcl-2 family.

8187:mustn1b
gene id: 8187:mustn1b
uniprot id: A0A4W6FCV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

8187:ogdhb
gene id: 8187:ogdhb
uniprot id: A0A4W6F0G6
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

8187:LOC108883778
gene id: 8187:LOC108883778
uniprot id: A0A4W6FNB1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108899247
gene id: 8187:LOC108899247
uniprot id: A0A4W6CCG0
names: Subcellular Location Annotation
messages: cytoskeleton

8187:zgc:172145
gene id: 8187:zgc:172145
uniprot id: A0A4W6DKR4
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8187:wnt3a
gene id: 8187:wnt3a
uniprot id: A0A4W6CCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:atg4da
gene id: 8187:atg4da
uniprot id: A0A4W6FWH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8187:LOC108898628
gene id: 8187:LOC108898628
uniprot id: A0A4W6EWY4
uniprot id: A0A4W6EWY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

8187:il17rd
gene id: 8187:il17rd
uniprot id: A0A4W6FWY0
names: Subcellular Location Annotation
messages: Membrane

8187:gsna
gene id: 8187:gsna
uniprot id: A0A4W6FD02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
messages: cytoskeleton

8187:st14b
gene id: 8187:st14b
uniprot id: A0A4W6FSJ3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:coq10a
gene id: 8187:coq10a
uniprot id: A0A4W6FG40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8187:tmtc2a
gene id: 8187:tmtc2a
uniprot id: A0A4W6C3B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8187:adss2
gene id: 8187:adss2
uniprot id: A0A4W6DKW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8187:pard3ba
gene id: 8187:pard3ba
uniprot id: A0A4W6G2Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

8187:LOC108873226
gene id: 8187:LOC108873226
uniprot id: A0A4W6CPV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8187:ppp1r14c
gene id: 8187:ppp1r14c
uniprot id: A0A4W6EDH5
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8187:LOC108901072
gene id: 8187:LOC108901072
uniprot id: A0A4W6FNA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8187:LOC108896442
gene id: 8187:LOC108896442
uniprot id: A0A4W6GBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

8187:gpr185b
gene id: 8187:gpr185b
uniprot id: A0A4W6CK02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108901123
gene id: 8187:LOC108901123
uniprot id: A0A4W6E4Z4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:prdx5
gene id: 8187:prdx5
uniprot id: A0A4W6F0X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

8187:rab38b
gene id: 8187:rab38b
uniprot id: A0A4W6FY47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8187:LOC108894815
gene id: 8187:LOC108894815
uniprot id: A0A4W6CI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

8187:ca15b
gene id: 8187:ca15b
uniprot id: A0A4W6G656
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8187:phactr3a
gene id: 8187:phactr3a
uniprot id: A0A4W6C0V0
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

8187:csnk1g1
gene id: 8187:csnk1g1
uniprot id: A0A4W6ETE5
uniprot id: A0A4W6EUC3
uniprot id: A0A4W6EVJ9
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

8187:LOC108879897
gene id: 8187:LOC108879897
uniprot id: A0A4W6CGM0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8187:LOC108895955
gene id: 8187:LOC108895955
uniprot id: A0A4W6F4J8
names: Subcellular Location Annotation
messages: Membrane

8187:tmcc3
gene id: 8187:tmcc3
uniprot id: A0A4W6G2I1
names: Similarity
messages: Belongs to the TEX28 family.

8187:lclat1
gene id: 8187:lclat1
uniprot id: A0A4W6EE11
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8187:xk
gene id: 8187:xk
uniprot id: A0A4W6FGC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8187:trmt6
gene id: 8187:trmt6
uniprot id: A0A4W6E0F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

8187:cdkn1d
gene id: 8187:cdkn1d
uniprot id: A0A4W6FLM3
names: Similarity
messages: Belongs to the CDI family.

8187:cndp1
gene id: 8187:cndp1
uniprot id: A0A4W6EUJ8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

8187:mcm9
gene id: 8187:mcm9
uniprot id: A0A4W6DNV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8187:LOC108883251
gene id: 8187:LOC108883251
uniprot id: A0A4W6F8X7
names: Similarity
messages: Belongs to the TGF-beta family.

8187:zfp36l1b
gene id: 8187:zfp36l1b
uniprot id: A0A4W6DKZ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8187:parvg
gene id: 8187:parvg
uniprot id: A0A4W6CZ32
names: Similarity
messages: Belongs to the parvin family.

8187:LOC108872865
gene id: 8187:LOC108872865
uniprot id: A0A4W6BV72
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

8187:isoc2
gene id: 8187:isoc2
uniprot id: A0A4W6D7V7
names: Similarity
messages: Belongs to the isochorismatase family.

8187:fam110a
gene id: 8187:fam110a
uniprot id: A0A4W6DYR2
names: Similarity
messages: Belongs to the FAM110 family.

8187:psmd2
gene id: 8187:psmd2
uniprot id: A0A4W6BWI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

8187:kdelr3
gene id: 8187:kdelr3
uniprot id: A0A4W6DL84
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:ythdf1
gene id: 8187:ythdf1
uniprot id: A0A4W6E3I8
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

8187:LOC108890264
gene id: 8187:LOC108890264
uniprot id: A0A4W6FF21
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:wnt9b
gene id: 8187:wnt9b
uniprot id: A0A4W6CPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:skib
gene id: 8187:skib
uniprot id: A0A4W6CGL3
names: Similarity
messages: Belongs to the SKI family.

8187:ndnf
gene id: 8187:ndnf
uniprot id: A0A4W6E0Y1
names: Subcellular Location Annotation
messages: Secreted

8187:polr3c
gene id: 8187:polr3c
uniprot id: A0A4W6FRC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

8187:pdhx
gene id: 8187:pdhx
uniprot id: A0A4W6EIQ5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

8187:yy1a
gene id: 8187:yy1a
uniprot id: A0A4W6FRE1
names: Similarity
messages: Belongs to the YY transcription factor family.

8187:LOC108894877
gene id: 8187:LOC108894877
uniprot id: A0A4W6DHW2
uniprot id: A0A4W6DIV0
names: Subcellular Location Annotation
messages: Membrane

8187:abhd3
gene id: 8187:abhd3
uniprot id: A0A4W6C515
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8187:trh
gene id: 8187:trh
uniprot id: A0A4W6D6S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

8187:arpc4l
gene id: 8187:arpc4l
uniprot id: A0A4W6F614
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

8187:uck1
gene id: 8187:uck1
uniprot id: A0A4W6BQF6
names: Similarity
messages: Belongs to the uridine kinase family.

8187:fam3c
gene id: 8187:fam3c
uniprot id: A0A4W6E5B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8187:ralyl
gene id: 8187:ralyl
uniprot id: A0A4W6E475
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

8187:copb2
gene id: 8187:copb2
uniprot id: A0A4W6F6P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

8187:actr1b
gene id: 8187:actr1b
uniprot id: A0A4W6FBQ5
names: Similarity
messages: Belongs to the actin family.

8187:LOC108877402
gene id: 8187:LOC108877402
uniprot id: A0A4W6DJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

8187:LOC108891850
gene id: 8187:LOC108891850
uniprot id: A0A4W6DR93
names: Similarity
messages: Belongs to the NXPE family.

8187:otud7a
gene id: 8187:otud7a
uniprot id: A0A4W6DDC3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:LOC108887364
gene id: 8187:LOC108887364
uniprot id: A0A4W6E5L3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8187:tpd52l2b
gene id: 8187:tpd52l2b
uniprot id: A0A4W6G0K3
uniprot id: A0A4W6G2H2
names: Similarity
messages: Belongs to the TPD52 family.

8187:pds5b
gene id: 8187:pds5b
uniprot id: A0A4W6FGZ9
names: Subcellular Location Annotation
messages: Nucleus

8187:ubald1a
gene id: 8187:ubald1a
uniprot id: A0A4W6G941
names: Similarity
messages: Belongs to the UBALD family.

8187:nme6
gene id: 8187:nme6
uniprot id: A0A4W6CVW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8187:cry5
gene id: 8187:cry5
uniprot id: A0A4W6FNX6
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8187:mex3a
gene id: 8187:mex3a
uniprot id: A0A4W6BPB8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:LOC108883151
gene id: 8187:LOC108883151
uniprot id: A0A4W6D985
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

8187:neflb
gene id: 8187:neflb
uniprot id: A0A4W6F645
names: Similarity
messages: Belongs to the intermediate filament family.

8187:drd5a
gene id: 8187:drd5a
uniprot id: A0A4W6D4B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:map7d1a
gene id: 8187:map7d1a
uniprot id: A0A4W6C1K5
uniprot id: A0A4W6C875
uniprot id: A0A4W6CA07
names: Similarity
messages: Belongs to the MAP7 family.

8187:rc3h1b
gene id: 8187:rc3h1b
uniprot id: A0A4W6E0L0
names: Subcellular Location Annotation
messages: P-body

8187:LOC108887604
gene id: 8187:LOC108887604
uniprot id: A0A4W6BP63
names: Subcellular Location Annotation
messages: Cytoplasm

8187:tmem167a
gene id: 8187:tmem167a
uniprot id: A0A4W6G8V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

8187:LOC108873562
gene id: 8187:LOC108873562
uniprot id: A0A4W6E3X8
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:gpr19
gene id: 8187:gpr19
uniprot id: A0A4W6F1N3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8187:LOC108882721
gene id: 8187:LOC108882721
uniprot id: A0A4W6CJZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:ercc1
gene id: 8187:ercc1
uniprot id: A0A4W6F253
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

8187:itk
gene id: 8187:itk
uniprot id: A0A4W6CDM6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8187:dusp8a
gene id: 8187:dusp8a
uniprot id: A0A4W6ENN1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8187:barhl1b
gene id: 8187:barhl1b
uniprot id: A0A4W6FCM3
names: Subcellular Location Annotation
messages: Nucleus

8187:dkk3a
gene id: 8187:dkk3a
uniprot id: A0A4W6G0G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

8187:boc
gene id: 8187:boc
uniprot id: A0A4W6DKV9
uniprot id: A0A4W6DM08
names: Subcellular Location Annotation
messages: Membrane

8187:lbx1b
gene id: 8187:lbx1b
uniprot id: A0A4W6CA11
names: Subcellular Location Annotation
messages: Nucleus

8187:vps37ba
gene id: 8187:vps37ba
uniprot id: A0A4W6G5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8187:cdc42se1
gene id: 8187:cdc42se1
uniprot id: A0A4W6DQV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

8187:ndufs3
gene id: 8187:ndufs3
uniprot id: A0A4W6BSD1
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

8187:kdm5bb
gene id: 8187:kdm5bb
uniprot id: A0A4W6EBH5
uniprot id: A0A4W6EE48
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

8187:slc66a3
gene id: 8187:slc66a3
uniprot id: A0A4W6FBQ7
names: Subcellular Location Annotation
messages: Membrane

8187:foxa3
gene id: 8187:foxa3
uniprot id: A0A4W6CYX6
names: Subcellular Location Annotation
messages: Nucleus

8187:scrn3
gene id: 8187:scrn3
uniprot id: A0A4W6EAA0
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

8187:mmp25b
gene id: 8187:mmp25b
uniprot id: A0A4W6G7A2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8187:grb14
gene id: 8187:grb14
uniprot id: A0A4W6FXX1
uniprot id: A0A4W6FXX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

8187:LOC108875170
gene id: 8187:LOC108875170
uniprot id: A0A4W6DMF5
names: Similarity
messages: Belongs to the peptidase A1 family.

8187:slc35a5
gene id: 8187:slc35a5
uniprot id: A0A4W6EC51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8187:rps27a
gene id: 8187:rps27a
uniprot id: A0A4W6C4C7
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

8187:ppa1a
gene id: 8187:ppa1a
uniprot id: A0A4W6EZB5
names: Similarity
messages: Belongs to the PPase family.

8187:nmbb
gene id: 8187:nmbb
uniprot id: A0A4W6FPL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

8187:ptdss2
gene id: 8187:ptdss2
uniprot id: A0A4W6CPW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:ajap1
gene id: 8187:ajap1
uniprot id: A0A4W6G8E5
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108884621
gene id: 8187:LOC108884621
uniprot id: A0A4W6FPL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

8187:fam118b
gene id: 8187:fam118b
uniprot id: A0A4W6CV47
names: Similarity
messages: Belongs to the FAM118 family.

8187:nudt6
gene id: 8187:nudt6
uniprot id: A0A4W6BW45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

8187:scml4
gene id: 8187:scml4
uniprot id: A0A4W6EAJ3
names: Similarity
messages: Belongs to the SCM family.

8187:cds2
gene id: 8187:cds2
uniprot id: A0A4W6ECB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

8187:LOC108875314
gene id: 8187:LOC108875314
uniprot id: A0A4W6DZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

8187:cpsf2
gene id: 8187:cpsf2
uniprot id: A0A4W6EJQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

8187:hapln4
gene id: 8187:hapln4
uniprot id: A0A4W6D9Q9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108894391
gene id: 8187:LOC108894391
uniprot id: A0A4W6F1R5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108897574
gene id: 8187:LOC108897574
uniprot id: A0A4W6G1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:dtx3
gene id: 8187:dtx3
uniprot id: A0A4W6EM29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8187:tmtopsb
gene id: 8187:tmtopsb
uniprot id: A0A4W6BPZ5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:tead1b
gene id: 8187:tead1b
uniprot id: A0A4W6G0C3
names: Subcellular Location Annotation
messages: Nucleus

8187:ndufaf3
gene id: 8187:ndufaf3
uniprot id: A0A4W6ES83
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

8187:LOC108883563
gene id: 8187:LOC108883563
uniprot id: A0A4W6E652
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8187:LOC108889506
gene id: 8187:LOC108889506
uniprot id: A0A4W6ES86
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:acss2l
gene id: 8187:acss2l
uniprot id: A0A4W6FQQ8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8187:LOC108882939
gene id: 8187:LOC108882939
uniprot id: A0A4W6F3R0
uniprot id: A0A4W6F3T0
uniprot id: A0A4W6F5L9
uniprot id: A0A4W6F723
uniprot id: A0A4W6F7K2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8187:uhrf1
gene id: 8187:uhrf1
uniprot id: A0A4W6CNW2
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

8187:mul1a
gene id: 8187:mul1a
uniprot id: A0A4W6E937
names: Subcellular Location Annotation
messages: Membrane

8187:mrpl16
gene id: 8187:mrpl16
uniprot id: A0A4W6DAQ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

8187:si:ch211-180f4.1
gene id: 8187:si:ch211-180f4.1
uniprot id: A0A4W6FZP0
names: Subcellular Location Annotation
messages: Membrane

8187:mrpl44
gene id: 8187:mrpl44
uniprot id: A0A4W6E6L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

8187:ndufb10
gene id: 8187:ndufb10
uniprot id: A0A4W6DU94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

8187:pth2
gene id: 8187:pth2
uniprot id: A0A4W6C6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8187:cpa6
gene id: 8187:cpa6
uniprot id: A0A4W6DY82
names: Similarity
messages: Belongs to the peptidase M14 family.

8187:pif1
gene id: 8187:pif1
uniprot id: A0A4W6FCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

8187:gnb5a
gene id: 8187:gnb5a
uniprot id: A0A4W6D625
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8187:LOC108900152
gene id: 8187:LOC108900152
uniprot id: A0A4W6DGD8
names: Subcellular Location Annotation
messages: Membrane

8187:mif
gene id: 8187:mif
uniprot id: A0A4W6EPI0
names: Similarity
messages: Belongs to the MIF family.

8187:LOC108874039
gene id: 8187:LOC108874039
uniprot id: A0A4W6CB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:syt1a
gene id: 8187:syt1a
uniprot id: A0A4W6C681
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

8187:mrpl53
gene id: 8187:mrpl53
uniprot id: A0A4W6DY62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

8187:ncapg
gene id: 8187:ncapg
uniprot id: A0A4W6BQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

8187:myd88
gene id: 8187:myd88
uniprot id: A0A4W6DB38
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm

8187:LOC108901853
gene id: 8187:LOC108901853
uniprot id: A0A4W6DVN0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8187:ergic1
gene id: 8187:ergic1
uniprot id: A0A4W6DFV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8187:zgc:63972
gene id: 8187:zgc:63972
uniprot id: A0A4W6BQ58
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8187:clptm1l
gene id: 8187:clptm1l
uniprot id: A0A4W6DRD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

8187:si:dkey-33c12.3
gene id: 8187:si:dkey-33c12.3
uniprot id: A0A4W6DSE9
names: Similarity
messages: Belongs to the intermediate filament family.

8187:LOC108884859
gene id: 8187:LOC108884859
uniprot id: A0A4W6EJD4
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

8187:LOC108880653
gene id: 8187:LOC108880653
uniprot id: A0A4W6DWX3
names: Similarity
messages: Belongs to the PHYHIP family.

8187:kcnq3
gene id: 8187:kcnq3
uniprot id: A0A4W6CL01
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:zgc:86896
gene id: 8187:zgc:86896
uniprot id: A0A4W6D473
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.

8187:dnm3a
gene id: 8187:dnm3a
uniprot id: A0A4W6CXG7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8187:irx2a
gene id: 8187:irx2a
uniprot id: A0A4W6EP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8187:scara5
gene id: 8187:scara5
uniprot id: A0A4W6DEN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCARA5 family.
messages: Cell membrane
messages: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways.
messages: Homotrimer.
messages: Membrane

8187:LOC108895497
gene id: 8187:LOC108895497
uniprot id: A0A4W6C0E2
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

8187:kdm2ab
gene id: 8187:kdm2ab
uniprot id: A0A4W6DHW3
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8187:LOC108901363
gene id: 8187:LOC108901363
uniprot id: A0A4W6D258
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:vps72a
gene id: 8187:vps72a
uniprot id: A0A4W6E110
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

8187:chrna4b
gene id: 8187:chrna4b
uniprot id: A0A4W6CM84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:pomgnt2
gene id: 8187:pomgnt2
uniprot id: A0A4W6EUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:pop7
gene id: 8187:pop7
uniprot id: A0A4W6EBP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like Alba family.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: nucleolus

8187:nr2f2
gene id: 8187:nr2f2
uniprot id: A0A4W6CNR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:gimap4
gene id: 8187:gimap4
uniprot id: A0A4W6FKC5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8187:aqp9b
gene id: 8187:aqp9b
uniprot id: A0A4W6DV87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8187:tgfbr2l
gene id: 8187:tgfbr2l
uniprot id: A0A4W6EXI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

8187:jpt1
gene id: 8187:jpt1
uniprot id: A0A4W6DVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

8187:si:ch73-61d6.3
gene id: 8187:si:ch73-61d6.3
uniprot id: A0A4W6CS86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

8187:bnip4
gene id: 8187:bnip4
uniprot id: A0A4W6D7Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8187:tbx5b
gene id: 8187:tbx5b
uniprot id: A0A4W6GAA3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8187:aida
gene id: 8187:aida
uniprot id: A0A4W6ERZ6
uniprot id: A0A4W6EV32
names: Similarity
messages: Belongs to the AIDA family.

8187:LOC108897170
gene id: 8187:LOC108897170
uniprot id: A0A4W6FCN0
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:lmbr1
gene id: 8187:lmbr1
uniprot id: A0A4W6FIZ7
names: Similarity
messages: Belongs to the LIMR family.

8187:etfb
gene id: 8187:etfb
uniprot id: A0A4W6BT12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

8187:exoc4
gene id: 8187:exoc4
uniprot id: A0A4W6BVI6
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

8187:piwil2
gene id: 8187:piwil2
uniprot id: A0A4W6EX50
names: Similarity
messages: Belongs to the argonaute family.

8187:snphb
gene id: 8187:snphb
uniprot id: A0A4W6BLP3
uniprot id: A0A4W6BQL4
uniprot id: A0A4W6BTH7
names: Subcellular Location Annotation
messages: Membrane

8187:ca7
gene id: 8187:ca7
uniprot id: A0A4W6C966
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8187:KEG24 p12
gene id: 8187:KEG24_p12
uniprot id: Q3IA75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8187:ctsh
gene id: 8187:ctsh
uniprot id: A0A4W6CA83
names: Similarity
messages: Belongs to the peptidase C1 family.

8187:coq5
gene id: 8187:coq5
uniprot id: A0A4W6E7U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

8187:LOC108886163
gene id: 8187:LOC108886163
uniprot id: A0A4W6BPV3
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8187:pax3b
gene id: 8187:pax3b
uniprot id: A0A4W6C0E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8187:LOC108877982
gene id: 8187:LOC108877982
uniprot id: A0A4W6G203
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8187:LOC108875693
gene id: 8187:LOC108875693
uniprot id: A0A4W6C5I8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

8187:borcs8
gene id: 8187:borcs8
uniprot id: A0A4W6DA53
uniprot id: A0A4W6DBA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

8187:lxn
gene id: 8187:lxn
uniprot id: A0A4W6CR91
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

8187:LOC108892900
gene id: 8187:LOC108892900
uniprot id: A0A4W6EI24
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8187:irf5
gene id: 8187:irf5
uniprot id: A0A4W6DFW6
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108877636
gene id: 8187:LOC108877636
uniprot id: A0A4W6D6Z8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:LOC108877826
gene id: 8187:LOC108877826
uniprot id: A0A4W6C4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

8187:cspg4
gene id: 8187:cspg4
uniprot id: A0A4W6CNZ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:ldb1a
gene id: 8187:ldb1a
uniprot id: A0A4W6CFX5
names: Similarity
messages: Belongs to the LDB family.

8187:pnpla7a
gene id: 8187:pnpla7a
uniprot id: A0A4W6C9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108879285
gene id: 8187:LOC108879285
uniprot id: A0A4W6DHL4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8187:ttyh2l
gene id: 8187:ttyh2l
uniprot id: A0A4W6G1J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8187:si:dkey-76k16.5
gene id: 8187:si:dkey-76k16.5
uniprot id: A0A4W6C3I5
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

8187:LOC108898479
gene id: 8187:LOC108898479
uniprot id: A0A4W6E3R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8187:LOC108900322
gene id: 8187:LOC108900322
uniprot id: A0A4W6CI42
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8187:comtd1
gene id: 8187:comtd1
uniprot id: A0A4W6DFE4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

8187:tfr1b
gene id: 8187:tfr1b
uniprot id: A0A4W6BSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

8187:LOC108875029
gene id: 8187:LOC108875029
uniprot id: A0A4W6F644
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8187:LOC108874692
gene id: 8187:LOC108874692
uniprot id: A0A4W6E5X4
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108902116
gene id: 8187:LOC108902116
uniprot id: A0A4W6E9M1
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8187:LOC108878708
gene id: 8187:LOC108878708
uniprot id: A0A4W6G9L5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108896721
gene id: 8187:LOC108896721
uniprot id: A0A4W6D435
names: Similarity
messages: Belongs to the opioid neuropeptide precursor family.

8187:LOC108888778
gene id: 8187:LOC108888778
uniprot id: A0A4W6EPM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8187:yod1
gene id: 8187:yod1
uniprot id: A0A4W6CQC2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Cleaves both polyubiquitin and di-ubiquitin.

8187:mark4b
gene id: 8187:mark4b
uniprot id: A0A4W6D247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8187:LOC108885477
gene id: 8187:LOC108885477
uniprot id: A0A4W6EEF0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

8187:vps4a
gene id: 8187:vps4a
uniprot id: A0A4W6EL61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8187:LOC108882770
gene id: 8187:LOC108882770
uniprot id: A0A4W6CBQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:ogt.1
gene id: 8187:ogt.1
uniprot id: A0A4W6DZQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

8187:vkorc1l1
gene id: 8187:vkorc1l1
uniprot id: A0A4W6EPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:asic2
gene id: 8187:asic2
uniprot id: A0A4W6CMJ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:prdm10
gene id: 8187:prdm10
uniprot id: A0A4W6CER6
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

8187:LOC108889836
gene id: 8187:LOC108889836
uniprot id: A0A4W6F256
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8187:si:ch211-201h21.5
gene id: 8187:si:ch211-201h21.5
uniprot id: A0A4W6DNM8
names: Similarity
messages: Belongs to the IUNH family.

8187:rnf13
gene id: 8187:rnf13
uniprot id: A0A4W6D999
names: Subcellular Location Annotation
messages: Membrane

8187:nfil3
gene id: 8187:nfil3
uniprot id: A0A4W6DKD4
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8187:LOC108898547
gene id: 8187:LOC108898547
uniprot id: A0A4W6C9Q6
uniprot id: A0A4W6CBG0
names: Similarity
messages: Belongs to the OSBP family.

8187:trpm3
gene id: 8187:trpm3
uniprot id: A0A4W6G882
names: Subcellular Location Annotation
messages: Membrane

8187:eno1a
gene id: 8187:eno1a
uniprot id: A0A4W6CC90
uniprot id: A0A4W6CHC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

8187:cpne7
gene id: 8187:cpne7
uniprot id: A0A4W6G1J4
names: Similarity
messages: Belongs to the copine family.

8187:cript
gene id: 8187:cript
uniprot id: A0A4W6EKY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

8187:il15ra
gene id: 8187:il15ra
uniprot id: A0A4W6FAM4
uniprot id: A0A4W6FAM9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:mllt11
gene id: 8187:mllt11
uniprot id: A0A4W6DND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

8187:car15
gene id: 8187:car15
uniprot id: A0A4W6CPY5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8187:tgm8
gene id: 8187:tgm8
uniprot id: A0A4W6ERY4
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8187:adam11
gene id: 8187:adam11
uniprot id: A0A4W6C3L0
uniprot id: A0A4W6C3L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:cep19
gene id: 8187:cep19
uniprot id: A0A4W6CQL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

8187:LOC108896174
gene id: 8187:LOC108896174
uniprot id: A0A4W6FAG6
names: Subcellular Location Annotation
messages: Membrane

8187:sumo2a
gene id: 8187:sumo2a
uniprot id: A0A4W6FRN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8187:LOC108882263
gene id: 8187:LOC108882263
uniprot id: A0A4W6DH18
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

8187:irak4
gene id: 8187:irak4
uniprot id: A0A4W6FJQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

8187:rps25
gene id: 8187:rps25
uniprot id: A0A4W6FZY1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

8187:khdrbs2
gene id: 8187:khdrbs2
uniprot id: A0A4W6G9B2
names: Similarity
messages: Belongs to the KHDRBS family.

8187:ehd2b
gene id: 8187:ehd2b
uniprot id: A0A4W6CJF4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8187:pts
gene id: 8187:pts
uniprot id: A0A4W6E6U7
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

8187:dcbld2
gene id: 8187:dcbld2
uniprot id: A0A4W6D9B6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108891702
gene id: 8187:LOC108891702
uniprot id: A0A4W6G873
names: Subcellular Location Annotation
messages: extracellular space

8187:mapre2
gene id: 8187:mapre2
uniprot id: A0A4W6CBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8187:skp1
gene id: 8187:skp1
uniprot id: A0A4W6DSS5
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

8187:si:ch211-114n24.6
gene id: 8187:si:ch211-114n24.6
uniprot id: A0A4W6EVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8187:fam20cb
gene id: 8187:fam20cb
uniprot id: A0A4W6F763
names: Similarity
messages: Belongs to the FAM20 family.

8187:ficd
gene id: 8187:ficd
uniprot id: A0A4W6GBF7
names: Similarity
messages: Belongs to the fic family.

8187:tada2b
gene id: 8187:tada2b
uniprot id: A0A4W6D9Z3
names: Subcellular Location Annotation
messages: Nucleus

8187:zgc:172121
gene id: 8187:zgc:172121
uniprot id: A0A4W6DMX1
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8187:rpe65a
gene id: 8187:rpe65a
uniprot id: A0A4W6D0Y4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8187:gpr146
gene id: 8187:gpr146
uniprot id: A0A4W6C4J2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108895484
gene id: 8187:LOC108895484
uniprot id: A0A4W6CVX5
names: Similarity
messages: Belongs to the cornifelin family.

8187:chst2b
gene id: 8187:chst2b
uniprot id: A0A4W6D3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8187:ufm1
gene id: 8187:ufm1
uniprot id: A0A4W6FRK3
names: Function
names: Similarity
messages: Belongs to the UFM1 family.
messages: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

8187:pacsin1b
gene id: 8187:pacsin1b
uniprot id: A0A4W6D7B6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell projection
messages: Cytoplasm
messages: Membrane

8187:slc5a8l
gene id: 8187:slc5a8l
uniprot id: A0A4W6CHQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8187:LOC108881623
gene id: 8187:LOC108881623
uniprot id: A0A4W6CQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

8187:tmem182a
gene id: 8187:tmem182a
uniprot id: A0A4W6CSQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

8187:adnpb
gene id: 8187:adnpb
uniprot id: A0A4W6G4C1
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108875081
gene id: 8187:LOC108875081
uniprot id: A0A4W6F341
uniprot id: A0A4W6F4K8
names: Subcellular Location Annotation
messages: Membrane

8187:rps16
gene id: 8187:rps16
uniprot id: A0A4W6C3V4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8187:LOC108900230
gene id: 8187:LOC108900230
uniprot id: A0A4W6EMA7
names: Subcellular Location Annotation
messages: Nucleus

8187:hgh1
gene id: 8187:hgh1
uniprot id: A0A4W6CBV7
names: Similarity
messages: Belongs to the HGH1 family.

8187:mdfi
gene id: 8187:mdfi
uniprot id: A0A4W6DLI5
names: Similarity
messages: Belongs to the MDFI family.

8187:smad9
gene id: 8187:smad9
uniprot id: A0A4W6FPI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108881905
gene id: 8187:LOC108881905
uniprot id: A0A4W6F3X8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8187:lingo2b
gene id: 8187:lingo2b
uniprot id: A0A4W6F8B8
names: Subcellular Location Annotation
messages: Membrane

8187:atp5f1e
gene id: 8187:atp5f1e
uniprot id: A0A4W6BTT9
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

8187:KEG24 p08
gene id: 8187:KEG24_p08
uniprot id: Q3IA71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

8187:pdgfrb
gene id: 8187:pdgfrb
uniprot id: A0A4W6C9G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8187:arsj
gene id: 8187:arsj
uniprot id: A0A4W6DKT2
names: Similarity
messages: Belongs to the sulfatase family.

8187:LOC108902770
gene id: 8187:LOC108902770
uniprot id: A0A4W6DZP2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

8187:LOC108880224
gene id: 8187:LOC108880224
uniprot id: A0A4W6DJ03
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:arid1aa
gene id: 8187:arid1aa
uniprot id: A0A4W6CKL0
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108875793
gene id: 8187:LOC108875793
uniprot id: A0A4W6FRN8
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8187:nck1b
gene id: 8187:nck1b
uniprot id: A0A4W6D8N5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

8187:LOC108885939
gene id: 8187:LOC108885939
uniprot id: A0A4W6FTB7
names: Similarity
messages: Belongs to the S-100 family.

8187:LOC108882217
gene id: 8187:LOC108882217
uniprot id: A0A4W6EJC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8187:ntd5
gene id: 8187:ntd5
uniprot id: A0A4W6D3F3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:LOC108880821
gene id: 8187:LOC108880821
uniprot id: A0A4W6EFZ6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8187:b3galt8
gene id: 8187:b3galt8
uniprot id: A0A4W6G6K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:ankrd13b
gene id: 8187:ankrd13b
uniprot id: A0A4W6CQY5
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8187:wfikkn1
gene id: 8187:wfikkn1
uniprot id: A0A4W6C2B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane
messages: Secreted

8187:pkn2a
gene id: 8187:pkn2a
uniprot id: A0A4W6FHZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

8187:LOC108888865
gene id: 8187:LOC108888865
uniprot id: A0A4W6FE80
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

8187:cacng5a
gene id: 8187:cacng5a
uniprot id: A0A4W6FU83
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

8187:mcur1
gene id: 8187:mcur1
uniprot id: A0A4W6G1C5
names: Similarity
messages: Belongs to the CCDC90 family.

8187:rorca
gene id: 8187:rorca
uniprot id: A0A4W6FUE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:adora2b
gene id: 8187:adora2b
uniprot id: A0A4W6ETP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108895804
gene id: 8187:LOC108895804
uniprot id: A0A4W6CLQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8187:LOC108880832
gene id: 8187:LOC108880832
uniprot id: A0A4W6EJP1
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

8187:LOC108885135
gene id: 8187:LOC108885135
uniprot id: A0A4W6G8Q3
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

8187:nop16
gene id: 8187:nop16
uniprot id: A0A4W6G8W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

8187:kctd3
gene id: 8187:kctd3
uniprot id: A0A4W6FXB3
names: Similarity
messages: Belongs to the KCTD3 family.

8187:pgfb
gene id: 8187:pgfb
uniprot id: A0A4W6F4Z3
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8187:elp6
gene id: 8187:elp6
uniprot id: A0A4W6CHE5
names: Similarity
messages: Belongs to the ELP6 family.

8187:fdxr
gene id: 8187:fdxr
uniprot id: A0A4W6FBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

8187:areg
gene id: 8187:areg
uniprot id: A0A4W6BRT9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108874698
gene id: 8187:LOC108874698
uniprot id: A0A4W6E9F1
names: Subcellular Location Annotation
messages: cytosol

8187:tnnt3a
gene id: 8187:tnnt3a
uniprot id: A0A4W6DMY6
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

8187:rpe
gene id: 8187:rpe
uniprot id: A0A4W6CKJ9
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

8187:ccl20a.3
gene id: 8187:ccl20a.3
uniprot id: A0A4W6E9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8187:dbnlb
gene id: 8187:dbnlb
uniprot id: A0A4W6G5C9
uniprot id: A0A4W6G5D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Early endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

8187:tmem163a
gene id: 8187:tmem163a
uniprot id: A0A4W6GAQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

8187:wnt7aa
gene id: 8187:wnt7aa
uniprot id: A0A4W6D1P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:prune
gene id: 8187:prune
uniprot id: A0A4W6DJS4
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

8187:fgfbp1b
gene id: 8187:fgfbp1b
uniprot id: A0A4W6EMU3
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8187:pard3ab
gene id: 8187:pard3ab
uniprot id: A0A4W6C9E0
uniprot id: A0A4W6C9G4
uniprot id: A0A4W6CG36
uniprot id: A0A4W6CGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

8187:cd40lg
gene id: 8187:cd40lg
uniprot id: A0A4W6ECR2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8187:dr1
gene id: 8187:dr1
uniprot id: A0A4W6CX36
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

8187:anapc11
gene id: 8187:anapc11
uniprot id: A0A4W6DBE9
names: Similarity
messages: Belongs to the RING-box family.

8187:dpp3
gene id: 8187:dpp3
uniprot id: A0A4W6EZY2
uniprot id: A0A4W6F1H5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

8187:LOC108883610
gene id: 8187:LOC108883610
uniprot id: A0A4W6EGE5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:LOC108899332
gene id: 8187:LOC108899332
uniprot id: A0A4W6DMX8
names: Similarity
messages: Belongs to the actin family.

8187:crtc1a
gene id: 8187:crtc1a
uniprot id: A0A4W6F734
uniprot id: A0A4W6F7R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

8187:prrt1
gene id: 8187:prrt1
uniprot id: A0A4W6EPB4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8187:nme7
gene id: 8187:nme7
uniprot id: A0A4W6DNI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: cilium axoneme
messages: lamellipodium
messages: ruffle

8187:rab38c
gene id: 8187:rab38c
uniprot id: A0A4W6EWK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8187:pdk2a
gene id: 8187:pdk2a
uniprot id: A0A4W6E0F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8187:pcsk1
gene id: 8187:pcsk1
uniprot id: A0A4W6CUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

8187:lrrn1
gene id: 8187:lrrn1
uniprot id: A0A4W6G0G2
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108873038
gene id: 8187:LOC108873038
uniprot id: A0A4W6F2E0
names: Subcellular Location Annotation
messages: Nucleus

8187:lrp13
gene id: 8187:lrp13
uniprot id: A0A4W6E778
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:babam1
gene id: 8187:babam1
uniprot id: A0A4W6CS62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

8187:LOC108893798
gene id: 8187:LOC108893798
uniprot id: A0A4W6D465
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

8187:pdcd4b
gene id: 8187:pdcd4b
uniprot id: A0A4W6DCV7
names: Similarity
messages: Belongs to the PDCD4 family.

8187:zeb2b
gene id: 8187:zeb2b
uniprot id: A0A4W6DTQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
messages: Nucleus

8187:kcnmb2
gene id: 8187:kcnmb2
uniprot id: A0A4W6FNW7
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108877237
gene id: 8187:LOC108877237
uniprot id: A0A4W6EE75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8187:rpl29
gene id: 8187:rpl29
uniprot id: A0A4W6DXR9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

8187:sdr42e1
gene id: 8187:sdr42e1
uniprot id: A0A4W6E6M0
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8187:cxcr2
gene id: 8187:cxcr2
uniprot id: A0A4W6GA02
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:zgc:110339
gene id: 8187:zgc:110339
uniprot id: A0A4W6FRP8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:taf13
gene id: 8187:taf13
uniprot id: A0A4W6G3J1
names: Subcellular Location Annotation
messages: Nucleus

8187:ppp1r15b
gene id: 8187:ppp1r15b
uniprot id: A0A4W6FY68
names: Similarity
messages: Belongs to the PPP1R15 family.

8187:slc23a4
gene id: 8187:slc23a4
uniprot id: A0A4W6BRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8187:LOC108897067
gene id: 8187:LOC108897067
uniprot id: A0A4W6EBC2
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

8187:dhrs7
gene id: 8187:dhrs7
uniprot id: A0A4W6FKF5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:nrm
gene id: 8187:nrm
uniprot id: A0A4W6E367
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

8187:LOC108898584
gene id: 8187:LOC108898584
uniprot id: A0A4W6EGI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8187:acot8
gene id: 8187:acot8
uniprot id: A0A4W6D489
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8187:LOC108877006
gene id: 8187:LOC108877006
uniprot id: A0A4W6FWI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:ube2m
gene id: 8187:ube2m
uniprot id: A0A4W6FBE1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:LOC108884221
gene id: 8187:LOC108884221
uniprot id: A0A4W6FGL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8187:tsr2
gene id: 8187:tsr2
uniprot id: A0A4W6ENV8
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

8187:tradd
gene id: 8187:tradd
uniprot id: A0A4W6BTU3
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

8187:gata2a
gene id: 8187:gata2a
uniprot id: A0A4W6FBL6
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108880718
gene id: 8187:LOC108880718
uniprot id: A0A4W6BM48
names: Subcellular Location Annotation
messages: extracellular space

8187:LOC108880801
gene id: 8187:LOC108880801
uniprot id: A0A4W6E9U4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane

8187:tmem39b
gene id: 8187:tmem39b
uniprot id: A0A4W6D6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

8187:lrit1a
gene id: 8187:lrit1a
uniprot id: A0A4W6E7Y6
names: Subcellular Location Annotation
messages: Membrane

8187:cltcl1
gene id: 8187:cltcl1
uniprot id: A0A4W6BWK0
uniprot id: A0A4W6C1W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

8187:tagln3b
gene id: 8187:tagln3b
uniprot id: A0A4W6DRJ4
names: Similarity
messages: Belongs to the calponin family.

8187:tlcd2
gene id: 8187:tlcd2
uniprot id: A0A4W6DLK4
names: Subcellular Location Annotation
messages: Membrane

8187:trim55b
gene id: 8187:trim55b
uniprot id: A0A4W6DS85
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

8187:serinc5
gene id: 8187:serinc5
uniprot id: A0A4W6GB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8187:vps28
gene id: 8187:vps28
uniprot id: A0A4W6DVV3
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

8187:tmem45a
gene id: 8187:tmem45a
uniprot id: A0A4W6DZ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

8187:si
gene id: 8187:si
uniprot id: A0A4W6E927
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:blmh
gene id: 8187:blmh
uniprot id: A0A4W6CR32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

8187:foxr1
gene id: 8187:foxr1
uniprot id: A0A4W6BRF5
names: Subcellular Location Annotation
messages: Nucleus

8187:eaf2
gene id: 8187:eaf2
uniprot id: A0A4W6EM16
names: Similarity
messages: Belongs to the EAF family.

8187:LOC108894707
gene id: 8187:LOC108894707
uniprot id: A0A4W6EKX0
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

8187:rpl34
gene id: 8187:rpl34
uniprot id: A0A4W6ECC4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

8187:nt5dc3
gene id: 8187:nt5dc3
uniprot id: A0A4W6F2A8
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

8187:slc25a17
gene id: 8187:slc25a17
uniprot id: A0A4W6C303
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:cryaa
gene id: 8187:cryaa
uniprot id: A0A4W6CS24
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8187:LOC108889618
gene id: 8187:LOC108889618
uniprot id: A0A4W6E325
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

8187:rad21l1
gene id: 8187:rad21l1
uniprot id: A0A4W6E2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8187:sf3b1
gene id: 8187:sf3b1
uniprot id: A0A4W6G8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

8187:LOC108873094
gene id: 8187:LOC108873094
uniprot id: A0A4W6D7L7
names: Similarity
messages: Belongs to the actin family.

8187:slc2a3b
gene id: 8187:slc2a3b
uniprot id: A0A4W6D9K6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8187:borcs7
gene id: 8187:borcs7
uniprot id: A0A4W6DT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS7 family.
messages: Lysosome membrane
messages: Membrane

8187:vps51
gene id: 8187:vps51
uniprot id: A0A4W6F315
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Endosome
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

8187:KEG24 p01
gene id: 8187:KEG24_p01
uniprot id: Q3IA64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

8187:cops9
gene id: 8187:cops9
uniprot id: A0A4W6BQ43
names: Similarity
messages: Belongs to the CSN9 family.

8187:impa1
gene id: 8187:impa1
uniprot id: A0A4W6CN86
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8187:LOC108874859
gene id: 8187:LOC108874859
uniprot id: A0A4W6ECR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

8187:LOC108882397
gene id: 8187:LOC108882397
uniprot id: A0A4W6FFS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8187:sema3bl
gene id: 8187:sema3bl
uniprot id: A0A4W6BXC6
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:tpra1
gene id: 8187:tpra1
uniprot id: A0A4W6C513
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

8187:cdk19
gene id: 8187:cdk19
uniprot id: A0A4W6BTD6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:arsg
gene id: 8187:arsg
uniprot id: A0A4W6DLW3
names: Similarity
messages: Belongs to the sulfatase family.

8187:ptn
gene id: 8187:ptn
uniprot id: A0A4W6C4L7
names: Similarity
messages: Belongs to the pleiotrophin family.

8187:xiap
gene id: 8187:xiap
uniprot id: A0A4W6CEK8
names: Similarity
messages: Belongs to the IAP family.

8187:pcyt1ba
gene id: 8187:pcyt1ba
uniprot id: A0A4W6CK65
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

8187:fgf10a
gene id: 8187:fgf10a
uniprot id: A0A4W6C378
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:zdhhc3b
gene id: 8187:zdhhc3b
uniprot id: A0A4W6E6Y1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8187:ethe1
gene id: 8187:ethe1
uniprot id: A0A4W6BSR1
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8187:vat1l
gene id: 8187:vat1l
uniprot id: A0A4W6G3Z9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8187:LOC108886133
gene id: 8187:LOC108886133
uniprot id: A0A4W6G8X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

8187:fez2a
gene id: 8187:fez2a
uniprot id: A0A4W6CJH9
uniprot id: A0A4W6CJI1
names: Similarity
messages: Belongs to the zygin family.

8187:LOC108898046
gene id: 8187:LOC108898046
uniprot id: A0A4W6CC69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

8187:dnaja
gene id: 8187:dnaja
uniprot id: A0A4W6DCB2
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108890654
gene id: 8187:LOC108890654
uniprot id: A0A4W6DVS0
names: Subcellular Location Annotation
messages: Membrane

8187:zgc:63587
gene id: 8187:zgc:63587
uniprot id: A0A4W6BZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

8187:fli1
gene id: 8187:fli1
uniprot id: A0A4W6CVG6
uniprot id: A0A4W6CVH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:LOC108876928
gene id: 8187:LOC108876928
uniprot id: A0A4W6ECG4
names: Similarity
messages: Belongs to the OSBP family.

8187:ctbp1
gene id: 8187:ctbp1
uniprot id: A0A4W6C9D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8187:kpnb3
gene id: 8187:kpnb3
uniprot id: A0A4W6ES56
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:LOC108877945
gene id: 8187:LOC108877945
uniprot id: A0A4W6ELF0
names: Subcellular Location Annotation
messages: Membrane

8187:dmrt1
gene id: 8187:dmrt1
uniprot id: A0A4W6FJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8187:hdac4
gene id: 8187:hdac4
uniprot id: A0A4W6G9N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8187:mcu
gene id: 8187:mcu
uniprot id: A0A4W6E6B4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

8187:cdc5l
gene id: 8187:cdc5l
uniprot id: A0A4W6BVW1
names: Similarity
messages: Belongs to the CEF1 family.

8187:sh3glb1a
gene id: 8187:sh3glb1a
uniprot id: A0A4W6C850
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Mitochondrion outer membrane

8187:meltf
gene id: 8187:meltf
uniprot id: A0A4W6DPF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.

8187:znf592
gene id: 8187:znf592
uniprot id: A0A4W6CAD2
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

8187:LOC108897722
gene id: 8187:LOC108897722
uniprot id: A0A4W6G2K3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8187:LOC108876287
gene id: 8187:LOC108876287
uniprot id: A0A4W6EYA3
names: Subcellular Location Annotation
messages: Nucleus

8187:dlc
gene id: 8187:dlc
uniprot id: A0A4W6FIK7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8187:bcl2l16
gene id: 8187:bcl2l16
uniprot id: A0A4W6G5L8
names: Similarity
messages: Belongs to the Bcl-2 family.

8187:si:dkey-63b1.1
gene id: 8187:si:dkey-63b1.1
uniprot id: A0A4W6BTJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8187:trhr2
gene id: 8187:trhr2
uniprot id: A0A4W6F3W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

8187:spdl1
gene id: 8187:spdl1
uniprot id: A0A4W6E503
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spindly family.
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex.
messages: kinetochore

8187:trmt1l
gene id: 8187:trmt1l
uniprot id: A0A4W6D3T3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

8187:smad6b
gene id: 8187:smad6b
uniprot id: A0A4W6DNI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108883053
gene id: 8187:LOC108883053
uniprot id: A0A4W6CPT8
names: Similarity
messages: Belongs to the CDI family.

8187:arl6ip4
gene id: 8187:arl6ip4
uniprot id: A0A4W6GBE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

8187:emc7b
gene id: 8187:emc7b
uniprot id: A0A4W6FU10
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

8187:rundc3b
gene id: 8187:rundc3b
uniprot id: A0A4W6BRP0
names: Similarity
messages: Belongs to the RUNDC3 family.

8187:si:ch211-71n6.4
gene id: 8187:si:ch211-71n6.4
uniprot id: A0A4W6CRG7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8187:hadh
gene id: 8187:hadh
uniprot id: A0A4W6CGS9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

8187:LOC108876306
gene id: 8187:LOC108876306
uniprot id: A0A4W6F3X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8187:LOC108895495
gene id: 8187:LOC108895495
uniprot id: A0A4W6C0I9
names: Similarity
messages: Belongs to the SPIN/STSY family.

8187:LOC108899795
gene id: 8187:LOC108899795
uniprot id: A0A4W6EYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8187:slc41a1
gene id: 8187:slc41a1
uniprot id: A0A4W6FIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8187:mtnr1aa
gene id: 8187:mtnr1aa
uniprot id: A0A4W6EVQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8187:tmem54a
gene id: 8187:tmem54a
uniprot id: A0A4W6DR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8187:mao
gene id: 8187:mao
uniprot id: A0A4W6EK59
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8187:lin54
gene id: 8187:lin54
uniprot id: A0A4W6CWP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

8187:gja4
gene id: 8187:gja4
uniprot id: A0A4W6D335
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8187:timm44
gene id: 8187:timm44
uniprot id: A0A4W6FID7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

8187:hoxd11a
gene id: 8187:hoxd11a
uniprot id: A0A4W6EBA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8187:hs3st3b1b
gene id: 8187:hs3st3b1b
uniprot id: A0A4W6E0A3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:LOC108898567
gene id: 8187:LOC108898567
uniprot id: A0A4W6CBR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8187:LOC108890018
gene id: 8187:LOC108890018
uniprot id: A0A4W6EGT6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:mmp15a
gene id: 8187:mmp15a
uniprot id: A0A4W6DBJ5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8187:nol11
gene id: 8187:nol11
uniprot id: A0A4W6FU42
names: Subcellular Location Annotation
messages: nucleolus

8187:gpr61
gene id: 8187:gpr61
uniprot id: A0A4W6CJX4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:rnf170
gene id: 8187:rnf170
uniprot id: A0A4W6DDJ3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108873080
gene id: 8187:LOC108873080
uniprot id: A0A4W6D893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8187:zgc:77880
gene id: 8187:zgc:77880
uniprot id: A0A4W6ESR2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8187:hoxa13b
gene id: 8187:hoxa13b
uniprot id: A0A4W6DJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8187:asrgl1
gene id: 8187:asrgl1
uniprot id: A0A4W6EWZ4
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8187:ndufa7
gene id: 8187:ndufa7
uniprot id: A0A4W6CJC0
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

8187:chrnb3a
gene id: 8187:chrnb3a
uniprot id: A0A4W6E6Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:celf3a
gene id: 8187:celf3a
uniprot id: A0A4W6FCE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

8187:LOC108876139
gene id: 8187:LOC108876139
uniprot id: A0A4W6D0X6
names: Similarity
messages: Belongs to the spectrin family.

8187:myg1
gene id: 8187:myg1
uniprot id: A0A4W6EE79
uniprot id: A0A4W6EGG2
names: Similarity
messages: Belongs to the MYG1 family.

8187:hoxb5a
gene id: 8187:hoxb5a
uniprot id: A0A4W6CAY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8187:lig1
gene id: 8187:lig1
uniprot id: A0A4W6C344
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.

8187:elavl2
gene id: 8187:elavl2
uniprot id: A0A4W6DTN5
names: Similarity
messages: Belongs to the RRM elav family.

8187:pard6a
gene id: 8187:pard6a
uniprot id: A0A4W6FRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

8187:mertka
gene id: 8187:mertka
uniprot id: A0A4W6F605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

8187:galr1b
gene id: 8187:galr1b
uniprot id: A0A4W6CP51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8187:aqp8a.1
gene id: 8187:aqp8a.1
uniprot id: A0A4W6G901
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8187:nr2c1
gene id: 8187:nr2c1
uniprot id: A0A4W6F3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:cul3b
gene id: 8187:cul3b
uniprot id: A0A4W6F5H3
names: Similarity
messages: Belongs to the cullin family.

8187:ric3b
gene id: 8187:ric3b
uniprot id: A0A4W6BWS6
names: Similarity
messages: Belongs to the ric-3 family.

8187:snrpb
gene id: 8187:snrpb
uniprot id: A0A4W6FH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

8187:galnt6
gene id: 8187:galnt6
uniprot id: A0A4W6ERZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8187:npffr2a
gene id: 8187:npffr2a
uniprot id: A0A4W6FGP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8187:nosip
gene id: 8187:nosip
uniprot id: A0A4W6E1D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
messages: Nucleus

8187:LOC108885586
gene id: 8187:LOC108885586
uniprot id: A0A4W6ESP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8187:ino80c
gene id: 8187:ino80c
uniprot id: A0A4W6CK64
names: Subcellular Location Annotation
messages: Nucleus

8187:opn8a
gene id: 8187:opn8a
uniprot id: A0A4W6DDN7
names: Subcellular Location Annotation
messages: Membrane

8187:smarcd1
gene id: 8187:smarcd1
uniprot id: A0A4W6CFG4
names: Similarity
messages: Belongs to the SMARCD family.

8187:lig4
gene id: 8187:lig4
uniprot id: A0A4W6E3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

8187:rad23ab
gene id: 8187:rad23ab
uniprot id: A0A4W6DTP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

8187:LOC108890633
gene id: 8187:LOC108890633
uniprot id: A0A4W6DQ20
names: Similarity
messages: Belongs to the TCAF family.

8187:lpar2b
gene id: 8187:lpar2b
uniprot id: A0A4W6GBD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

8187:araf
gene id: 8187:araf
uniprot id: A0A4W6FQ18
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

8187:LOC108878058
gene id: 8187:LOC108878058
uniprot id: A0A4W6F4E3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:elf1
gene id: 8187:elf1
uniprot id: A0A4W6DD62
uniprot id: A0A4W6DEA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:ilvbl
gene id: 8187:ilvbl
uniprot id: A0A4W6CV24
names: Similarity
messages: Belongs to the TPP enzyme family.

8187:phactr1
gene id: 8187:phactr1
uniprot id: A0A4W6FA02
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

8187:cetn4
gene id: 8187:cetn4
uniprot id: A0A4W6BVZ6
names: Similarity
messages: Belongs to the centrin family.

8187:opa3
gene id: 8187:opa3
uniprot id: A0A4W6CG02
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

8187:lmln
gene id: 8187:lmln
uniprot id: A0A4W6ESA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

8187:LOC108881923
gene id: 8187:LOC108881923
uniprot id: A0A4W6FC38
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

8187:irx5b
gene id: 8187:irx5b
uniprot id: A0A4W6FYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8187:stmn4l
gene id: 8187:stmn4l
uniprot id: A0A4W6CSE1
names: Similarity
messages: Belongs to the stathmin family.

8187:LOC108885900
gene id: 8187:LOC108885900
uniprot id: A0A4W6FN39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8187:coq10b
gene id: 8187:coq10b
uniprot id: A0A4W6CXV6
uniprot id: A0A4W6FGD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8187:LOC108880783
gene id: 8187:LOC108880783
uniprot id: A0A4W6CF27
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8187:tcf25
gene id: 8187:tcf25
uniprot id: A0A4W6C5S0
names: Similarity
messages: Belongs to the TCF25 family.

8187:LOC108881292
gene id: 8187:LOC108881292
uniprot id: A0A4W6FCQ4
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8187:rps6kb1a
gene id: 8187:rps6kb1a
uniprot id: A0A4W6EAZ3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8187:ca4b
gene id: 8187:ca4b
uniprot id: A0A4W6DNN7
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8187:acta1b
gene id: 8187:acta1b
uniprot id: A0A4W6G0X0
names: Similarity
messages: Belongs to the actin family.

8187:cited4b
gene id: 8187:cited4b
uniprot id: A0A4W6DH95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

8187:slc9a8
gene id: 8187:slc9a8
uniprot id: A0A4W6DXP7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

8187:LOC108880480
gene id: 8187:LOC108880480
uniprot id: A0A4W6DWY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8187:acss3
gene id: 8187:acss3
uniprot id: A0A4W6BY44
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8187:LOC108875936
gene id: 8187:LOC108875936
uniprot id: A0A4W6DLM4
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108872409
gene id: 8187:LOC108872409
uniprot id: A0A4W6E9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

8187:vamp1a
gene id: 8187:vamp1a
uniprot id: A0A4W6FLJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8187:dgkaa
gene id: 8187:dgkaa
uniprot id: A0A4W6FFC0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic diacylglycerol kinase family.
messages: Monomer.

8187:LOC108872827
gene id: 8187:LOC108872827
uniprot id: A0A4W6G141
names: Subcellular Location Annotation
messages: Cytoplasm

8187:mcoln3a
gene id: 8187:mcoln3a
uniprot id: A0A4W6BM36
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8187:LOC108884994
gene id: 8187:LOC108884994
uniprot id: A0A4W6FTR2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8187:ccdc85cb
gene id: 8187:ccdc85cb
uniprot id: A0A4W6DAF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

8187:coro1a
gene id: 8187:coro1a
uniprot id: A0A4W6CI88
names: Similarity
messages: Belongs to the WD repeat coronin family.

8187:fgf14
gene id: 8187:fgf14
uniprot id: A0A4W6DF74
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:LOC108896132
gene id: 8187:LOC108896132
uniprot id: A0A4W6FCA9
names: Subcellular Location Annotation
messages: Nucleus

8187:nab2
gene id: 8187:nab2
uniprot id: A0A4W6FVP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

8187:dapk2a
gene id: 8187:dapk2a
uniprot id: A0A4W6CEL6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:fgf19
gene id: 8187:fgf19
uniprot id: A0A4W6EP60
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:ckba
gene id: 8187:ckba
uniprot id: A0A4W6CA66
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8187:LOC108889424
gene id: 8187:LOC108889424
uniprot id: A0A4W6DIG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

8187:ephb2a
gene id: 8187:ephb2a
uniprot id: A0A4W6CUE9
names: Subcellular Location Annotation
messages: Membrane

8187:st8sia6
gene id: 8187:st8sia6
uniprot id: A0A4W6FID0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8187:ptpn11b
gene id: 8187:ptpn11b
uniprot id: A0A4W6C3C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

8187:LOC108888878
gene id: 8187:LOC108888878
uniprot id: A0A4W6FEK1
names: Subcellular Location Annotation
messages: extracellular space

8187:vta1
gene id: 8187:vta1
uniprot id: A0A4W6EP28
uniprot id: A0A4W6EQ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

8187:map2k4a
gene id: 8187:map2k4a
uniprot id: A0A4W6EA05
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:ube2ib
gene id: 8187:ube2ib
uniprot id: A0A4W6FZH9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:coq6
gene id: 8187:coq6
uniprot id: A0A4W6F3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

8187:cdipt
gene id: 8187:cdipt
uniprot id: A0A4W6DDX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

8187:si:cabz01101003.1
gene id: 8187:si:cabz01101003.1
uniprot id: A0A4W6C7N7
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

8187:slc2a11a
gene id: 8187:slc2a11a
uniprot id: A0A4W6D6T8
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8187:chrm3a
gene id: 8187:chrm3a
uniprot id: A0A4W6EDS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8187:LOC108893942
gene id: 8187:LOC108893942
uniprot id: A0A4W6DLL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:atp5mf
gene id: 8187:atp5mf
uniprot id: A0A4W6DCK0
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

8187:ak6
gene id: 8187:ak6
uniprot id: A0A4W6E6J9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

8187:ldb1b
gene id: 8187:ldb1b
uniprot id: A0A4W6CGV3
names: Similarity
messages: Belongs to the LDB family.

8187:rpn1
gene id: 8187:rpn1
uniprot id: A0A4W6FCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8187:znf277
gene id: 8187:znf277
uniprot id: A0A4W6FET9
names: Similarity
messages: Belongs to the ZNF277 family.

8187:arl6
gene id: 8187:arl6
uniprot id: A0A4W6C9H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

8187:rad9a
gene id: 8187:rad9a
uniprot id: A0A4W6DG91
names: Similarity
messages: Belongs to the rad9 family.

8187:cntn5
gene id: 8187:cntn5
uniprot id: A0A4W6CAV0
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108899695
gene id: 8187:LOC108899695
uniprot id: A0A4W6CRK0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8187:ublcp1
gene id: 8187:ublcp1
uniprot id: A0A4W6F0U4
names: Subcellular Location Annotation
messages: Nucleus

8187:cog8
gene id: 8187:cog8
uniprot id: A0A4W6CUD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG8 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane

8187:wnt9a
gene id: 8187:wnt9a
uniprot id: A0A4W6CC99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:mrps16
gene id: 8187:mrps16
uniprot id: A0A4W6G0G5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

8187:ddx21
gene id: 8187:ddx21
uniprot id: A0A4W6G370
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

8187:LOC108872970
gene id: 8187:LOC108872970
uniprot id: A0A4W6G3Y9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:mtm1
gene id: 8187:mtm1
uniprot id: A0A4W6DLE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8187:trmt2a
gene id: 8187:trmt2a
uniprot id: A0A4W6EQ04
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:b9d2
gene id: 8187:b9d2
uniprot id: A0A4W6DW02
names: Subcellular Location Annotation
messages: cilium basal body

8187:lix1l
gene id: 8187:lix1l
uniprot id: A0A4W6E0J6
names: Similarity
messages: Belongs to the LIX1 family.

8187:colgalt2b
gene id: 8187:colgalt2b
uniprot id: A0A4W6FUV8
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8187:si:cabz01090165.1
gene id: 8187:si:cabz01090165.1
uniprot id: A0A4W6D409
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108876744
gene id: 8187:LOC108876744
uniprot id: A0A4W6CX86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

8187:elapor2a
gene id: 8187:elapor2a
uniprot id: A0A4W6DD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8187:pde4a
gene id: 8187:pde4a
uniprot id: A0A4W6BUG3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8187:ddost
gene id: 8187:ddost
uniprot id: A0A4W6BLG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

8187:dhdds
gene id: 8187:dhdds
uniprot id: A0A4W6C435
names: Similarity
messages: Belongs to the UPP synthase family.

8187:rsad2
gene id: 8187:rsad2
uniprot id: A0A3G3NEE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RSAD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:tspan18b
gene id: 8187:tspan18b
uniprot id: A0A4W6CS28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:olfm1b
gene id: 8187:olfm1b
uniprot id: A0A4W6F097
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8187:LOC108883763
gene id: 8187:LOC108883763
uniprot id: A0A4W6FP98
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8187:rftn1a
gene id: 8187:rftn1a
uniprot id: A0A4W6EAC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

8187:LOC108889787
gene id: 8187:LOC108889787
uniprot id: A0A4W6CAJ1
names: Subcellular Location Annotation
messages: Cytoplasm

8187:hoxc8a
gene id: 8187:hoxc8a
uniprot id: A0A4W6FJR9
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108874424
gene id: 8187:LOC108874424
uniprot id: A0A4W6ESW3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:LOC108873753
gene id: 8187:LOC108873753
uniprot id: A0A4W6CP73
uniprot id: A0A4W6CPB0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:arpc2
gene id: 8187:arpc2
uniprot id: A0A4W6F1I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

8187:dcp1b
gene id: 8187:dcp1b
uniprot id: A0A4W6EHR9
names: Similarity
messages: Belongs to the DCP1 family.

8187:gtf2a2
gene id: 8187:gtf2a2
uniprot id: A0A4W6CSE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

8187:LOC108889279
gene id: 8187:LOC108889279
uniprot id: A0A4W6F3Z8
names: Similarity
messages: Belongs to the DNase I family.

8187:slc17a8
gene id: 8187:slc17a8
uniprot id: A0A4W6EA87
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108898018
gene id: 8187:LOC108898018
uniprot id: A0A4W6DJH8
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8187:LOC108874588
gene id: 8187:LOC108874588
uniprot id: A0A4W6EEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8187:LOC108888213
gene id: 8187:LOC108888213
uniprot id: A0A4W6CAR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

8187:ntn2
gene id: 8187:ntn2
uniprot id: A0A4W6BN83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108898948
gene id: 8187:LOC108898948
uniprot id: A0A4W6F278
names: Subcellular Location Annotation
messages: Membrane

8187:map2k5
gene id: 8187:map2k5
uniprot id: A0A4W6BRE7
uniprot id: A0A4W6BTY6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:fabp2
gene id: 8187:fabp2
uniprot id: R4N170
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8187:gna13b
gene id: 8187:gna13b
uniprot id: A0A4W6D4C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

8187:wnt1
gene id: 8187:wnt1
uniprot id: A0A4W6F8N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8187:cfd
gene id: 8187:cfd
uniprot id: A0A4W6C1F9
names: Subcellular Location Annotation
messages: extracellular space

8187:eml1
gene id: 8187:eml1
uniprot id: A0A4W6FED7
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8187:hs2st1a
gene id: 8187:hs2st1a
uniprot id: A0A4W6FJ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:efna3b
gene id: 8187:efna3b
uniprot id: A0A4W6FUJ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108880840
gene id: 8187:LOC108880840
uniprot id: A0A4W6EKM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:cryz
gene id: 8187:cryz
uniprot id: A0A4W6BRU2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8187:sumo3b
gene id: 8187:sumo3b
uniprot id: A0A4W6FL64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8187:celf5a
gene id: 8187:celf5a
uniprot id: A0A4W6C647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

8187:LOC108881966
gene id: 8187:LOC108881966
uniprot id: A0A4W6ES44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:pglyrp2
gene id: 8187:pglyrp2
uniprot id: A0A4W6FP12
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

8187:hoxd3a
gene id: 8187:hoxd3a
uniprot id: A0A4W6EBQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8187:rgma
gene id: 8187:rgma
uniprot id: A0A4W6CNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

8187:LOC108886282
gene id: 8187:LOC108886282
uniprot id: A0A4W6D2I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8187:mrs2
gene id: 8187:mrs2
uniprot id: A0A4W6CDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

8187:psma8
gene id: 8187:psma8
uniprot id: A0A4W6DB51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8187:utp11
gene id: 8187:utp11
uniprot id: A0A4W6C7G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

8187:hopx
gene id: 8187:hopx
uniprot id: A0A4W6CK74
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108901702
gene id: 8187:LOC108901702
uniprot id: A0A4W6C269
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8187:cldn10e
gene id: 8187:cldn10e
uniprot id: A0A4W6DIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8187:prkcda
gene id: 8187:prkcda
uniprot id: A0A4W6EM04
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.
messages: Cytoplasm
messages: Interacts with PDPK1 (via N-terminal region), RAD9A, CDCP1, MUC1 and VASP.
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: perinuclear region

8187:gkap1
gene id: 8187:gkap1
uniprot id: A0A4W6BJ25
names: Similarity
messages: Belongs to the GKAP1 family.

8187:mterf4
gene id: 8187:mterf4
uniprot id: A0A4W6E7I3
names: Similarity
messages: Belongs to the mTERF family.

8187:zgc:101810
gene id: 8187:zgc:101810
uniprot id: A0A4W6DT94
names: Similarity
messages: Belongs to the actin family.

8187:caprin2
gene id: 8187:caprin2
uniprot id: A0A4W6EUA3
uniprot id: A0A4W6EV84
names: Similarity
messages: Belongs to the caprin family.

8187:tmem14ca
gene id: 8187:tmem14ca
uniprot id: A0A4W6D159
names: Similarity
messages: Belongs to the TMEM14 family.

8187:b4galnt1a
gene id: 8187:b4galnt1a
uniprot id: A0A4W6F809
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:agap3
gene id: 8187:agap3
uniprot id: A0A4W6CHU3
names: Similarity
messages: Belongs to the centaurin gamma-like family.

8187:rpn2
gene id: 8187:rpn2
uniprot id: A0A4W6D563
uniprot id: A0A4W6D5G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8187:tgm2l
gene id: 8187:tgm2l
uniprot id: A0A4W6DDY7
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8187:LOC108882962
gene id: 8187:LOC108882962
uniprot id: A0A4W6E9Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

8187:LOC108883426
gene id: 8187:LOC108883426
uniprot id: A0A4W6DB63
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

8187:mmp23ba
gene id: 8187:mmp23ba
uniprot id: A0A4W6BSP8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:pcsk2
gene id: 8187:pcsk2
uniprot id: A0A4W6DHT1
names: Similarity
messages: Belongs to the peptidase S8 family.

8187:eif4ebp3l
gene id: 8187:eif4ebp3l
uniprot id: A0A4W6CEI9
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8187:dync1li1
gene id: 8187:dync1li1
uniprot id: A0A4W6CRM9
uniprot id: A0A4W6CRQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

8187:kif3b
gene id: 8187:kif3b
uniprot id: A0A4W6BXR0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8187:pelo
gene id: 8187:pelo
uniprot id: A0A4W6CQL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.
messages: Cytoplasm

8187:pde4ba
gene id: 8187:pde4ba
uniprot id: A0A4W6D3V7
uniprot id: A0A4W6D3Z0
uniprot id: A0A4W6D3Z6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8187:marveld3
gene id: 8187:marveld3
uniprot id: A0A4W6E9B7
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108893405
gene id: 8187:LOC108893405
uniprot id: A0A4W6EQ19
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8187:bmp3
gene id: 8187:bmp3
uniprot id: A0A4W6EDP8
names: Similarity
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.

8187:isca1
gene id: 8187:isca1
uniprot id: A0A4W6BJ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

8187:elk1
gene id: 8187:elk1
uniprot id: A0A4W6FYN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:slc43a2b
gene id: 8187:slc43a2b
uniprot id: A0A4W6DB07
names: Subcellular Location Annotation
messages: Membrane

8187:emx3
gene id: 8187:emx3
uniprot id: A0A4W6CQ08
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108885003
gene id: 8187:LOC108885003
uniprot id: A0A4W6FTI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:ppm1da
gene id: 8187:ppm1da
uniprot id: A0A4W6CDB9
names: Similarity
messages: Belongs to the PP2C family.

8187:xkr5b
gene id: 8187:xkr5b
uniprot id: A0A4W6G0X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8187:taf6l
gene id: 8187:taf6l
uniprot id: A0A4W6EB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8187:LOC108899128
gene id: 8187:LOC108899128
uniprot id: A0A4W6BUZ5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

8187:LOC108892850
gene id: 8187:LOC108892850
uniprot id: A0A4W6F5R3
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108901386
gene id: 8187:LOC108901386
uniprot id: A0A4W6CYF2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8187:csnk2a2b
gene id: 8187:csnk2a2b
uniprot id: A0A4W6EK54
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108879043
gene id: 8187:LOC108879043
uniprot id: A0A4W6D591
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHAF1A family.
messages: Nucleus

8187:man1a1
gene id: 8187:man1a1
uniprot id: A0A4W6ET65
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8187:LOC108883167
gene id: 8187:LOC108883167
uniprot id: A0A4W6C6B1
names: Similarity
messages: Belongs to the S-100 family.

8187:adamts15a
gene id: 8187:adamts15a
uniprot id: A0A4W6BVA2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:LOC108887181
gene id: 8187:LOC108887181
uniprot id: A0A4W6GB90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:rps19bp1
gene id: 8187:rps19bp1
uniprot id: A0A4W6CX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

8187:slc6a3
gene id: 8187:slc6a3
uniprot id: A0A4W6ELX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8187:ncaph2
gene id: 8187:ncaph2
uniprot id: A0A4W6F5B6
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

8187:tmem38b
gene id: 8187:tmem38b
uniprot id: A0A4W6CG42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

8187:ccne1
gene id: 8187:ccne1
uniprot id: A0A4W6D663
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:LOC108882264
gene id: 8187:LOC108882264
uniprot id: A0A4W6DH43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8187:myorg
gene id: 8187:myorg
uniprot id: A0A4W6CS05
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8187:kpna1
gene id: 8187:kpna1
uniprot id: A0A4W6DJC0
names: Similarity
messages: Belongs to the importin alpha family.

8187:snx5
gene id: 8187:snx5
uniprot id: A0A4W6C0P9
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

8187:slc30a9
gene id: 8187:slc30a9
uniprot id: A0A4W6FIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

8187:prkar1b
gene id: 8187:prkar1b
uniprot id: A0A4W6BZ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8187:hnf1a
gene id: 8187:hnf1a
uniprot id: A0A4W6F3Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

8187:LOC108888911
gene id: 8187:LOC108888911
uniprot id: A0A4W6DFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8187:slc10a2
gene id: 8187:slc10a2
uniprot id: A0A4W6EIU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

8187:hoxa1a
gene id: 8187:hoxa1a
uniprot id: A0A4W6EBW6
names: Subcellular Location Annotation
messages: Nucleus

8187:cdc42se2
gene id: 8187:cdc42se2
uniprot id: A0A4W6FUW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

8187:tamm41
gene id: 8187:tamm41
uniprot id: A0A4W6EZU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

8187:uxt
gene id: 8187:uxt
uniprot id: A0A4W6FXQ0
names: Similarity
messages: Belongs to the UXT family.

8187:psmb11a
gene id: 8187:psmb11a
uniprot id: A0A4W6CST5
names: Subcellular Location Annotation
messages: Nucleus

8187:myoz2b
gene id: 8187:myoz2b
uniprot id: A0A4W6C3G6
names: Similarity
messages: Belongs to the myozenin family.

8187:meis2a
gene id: 8187:meis2a
uniprot id: A0A4W6EM34
uniprot id: A0A4W6ENU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8187:LOC108884281
gene id: 8187:LOC108884281
uniprot id: A0A4W6BP06
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8187:LOC108902975
gene id: 8187:LOC108902975
uniprot id: A0A4W6BZX0
names: Similarity
messages: Belongs to the globin family.

8187:abracl
gene id: 8187:abracl
uniprot id: A0A4W6FSR4
names: Similarity
messages: Belongs to the costars family.

8187:tspan4b
gene id: 8187:tspan4b
uniprot id: A0A4W6DYA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:LOC108893081
gene id: 8187:LOC108893081
uniprot id: A0A4W6EI20
uniprot id: A0A4W6EKG6
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

8187:tubd1
gene id: 8187:tubd1
uniprot id: A0A4W6CS43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

8187:orc1
gene id: 8187:orc1
uniprot id: A0A4W6D035
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

8187:LOC108888194
gene id: 8187:LOC108888194
uniprot id: A0A4W6C2E2
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

8187:calcr
gene id: 8187:calcr
uniprot id: A0A4W6ET89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

8187:ntm
gene id: 8187:ntm
uniprot id: A0A4W6DST0
uniprot id: A0A4W6DVQ5
names: Subcellular Location Annotation
messages: Membrane

8187:calcrlb
gene id: 8187:calcrlb
uniprot id: A0A4W6D8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

8187:serinc1
gene id: 8187:serinc1
uniprot id: A0A4W6DQK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8187:ss18
gene id: 8187:ss18
uniprot id: A0A4W6DB85
uniprot id: A0A4W6DC09
names: Similarity
messages: Belongs to the SS18 family.

8187:gorasp2
gene id: 8187:gorasp2
uniprot id: A0A4W6FUH2
names: Similarity
messages: Belongs to the GORASP family.

8187:slc35a2
gene id: 8187:slc35a2
uniprot id: A0A4W6FYL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108894316
gene id: 8187:LOC108894316
uniprot id: A0A4W6CD40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:kcnk3b
gene id: 8187:kcnk3b
uniprot id: A0A4W6DKS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8187:LOC108880115
gene id: 8187:LOC108880115
uniprot id: A0A4W6F8A4
names: Similarity
messages: Belongs to the EEIG family.

8187:elk4
gene id: 8187:elk4
uniprot id: A0A4W6FHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:ppm1na
gene id: 8187:ppm1na
uniprot id: A0A4W6EU33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8187:LOC108883064
gene id: 8187:LOC108883064
uniprot id: A0A4W6CT39
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8187:serpinh2
gene id: 8187:serpinh2
uniprot id: A0A4W6EBG5
names: Similarity
messages: Belongs to the serpin family.

8187:si:dkey-6i22.5
gene id: 8187:si:dkey-6i22.5
uniprot id: A0A4W6EKX0
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

8187:rbbp4
gene id: 8187:rbbp4
uniprot id: A0A4W6FS11
names: Subcellular Location Annotation
messages: Nucleus

8187:fbxo45
gene id: 8187:fbxo45
uniprot id: A0A4W6C834
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

8187:hs3st1l2
gene id: 8187:hs3st1l2
uniprot id: A0A4W6FLT5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:snx21
gene id: 8187:snx21
uniprot id: A0A4W6G4A1
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

8187:zdhhc21
gene id: 8187:zdhhc21
uniprot id: A0A4W6ED01
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8187:hoxc11a
gene id: 8187:hoxc11a
uniprot id: A0A4W6FLH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8187:cpdp
gene id: 8187:cpdp
uniprot id: A0A4W6FNW0
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

8187:cdh15
gene id: 8187:cdh15
uniprot id: A0A4W6CIX8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8187:LOC108888707
gene id: 8187:LOC108888707
uniprot id: A0A4W6DKV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum
messages: flagellum axoneme

8187:LOC108902129
gene id: 8187:LOC108902129
uniprot id: A0A4W6E0J0
names: Subcellular Location Annotation
messages: extracellular space

8187:znf711
gene id: 8187:znf711
uniprot id: A0A4W6E1G0
names: Subcellular Location Annotation
messages: Nucleus

8187:pigg
gene id: 8187:pigg
uniprot id: A0A4W6FSN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:smu1b
gene id: 8187:smu1b
uniprot id: A0A4W6C1A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

8187:arsa
gene id: 8187:arsa
uniprot id: A0A4W6DMZ3
names: Similarity
messages: Belongs to the sulfatase family.

8187:gmfg
gene id: 8187:gmfg
uniprot id: A0A4W6G5G1
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

8187:ddc
gene id: 8187:ddc
uniprot id: A0A4W6EGL9
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8187:cemip
gene id: 8187:cemip
uniprot id: A0A4W6D615
names: Similarity
messages: Belongs to the CEMIP family.

8187:xkr6a
gene id: 8187:xkr6a
uniprot id: A0A4W6FGR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8187:st6gal1
gene id: 8187:st6gal1
uniprot id: A0A4W6F8R7
uniprot id: A0A4W6F9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8187:LOC108896747
gene id: 8187:LOC108896747
uniprot id: A0A4W6D2I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

8187:slc51a
gene id: 8187:slc51a
uniprot id: A0A4W6CFS2
names: Subcellular Location Annotation
messages: Membrane

8187:mlf2
gene id: 8187:mlf2
uniprot id: A0A4W6CIL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

8187:cfap157
gene id: 8187:cfap157
uniprot id: A0A4W6CRB7
names: Similarity
messages: Belongs to the CFAP157 family.

8187:cdk5rap1
gene id: 8187:cdk5rap1
uniprot id: A0A4W6D5Q5
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

8187:cplx2a
gene id: 8187:cplx2a
uniprot id: A0A4W6D2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8187:LOC108888092
gene id: 8187:LOC108888092
uniprot id: A0A4W6D7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:adam22
gene id: 8187:adam22
uniprot id: A0A4W6BV18
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108886219
gene id: 8187:LOC108886219
uniprot id: A0A4W6C5C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:LOC108877753
gene id: 8187:LOC108877753
uniprot id: A0A4W6EYE6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

8187:psmc5
gene id: 8187:psmc5
uniprot id: A0A4W6E7A5
names: Similarity
messages: Belongs to the AAA ATPase family.

8187:trappc5
gene id: 8187:trappc5
uniprot id: A0A4W6FNL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

8187:trmt112
gene id: 8187:trmt112
uniprot id: A0A4W6EY04
names: Similarity
messages: Belongs to the TRM112 family.

8187:LOC108873569
gene id: 8187:LOC108873569
uniprot id: A0A4W6CCU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

8187:LOC108895237
gene id: 8187:LOC108895237
uniprot id: A0A4W6E398
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8187:dlx1a
gene id: 8187:dlx1a
uniprot id: A0A4W6FWB3
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108881525
gene id: 8187:LOC108881525
uniprot id: A0A4W6G651
uniprot id: A0A4W6G669
uniprot id: A0A4W6G7J1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:rpl4
gene id: 8187:rpl4
uniprot id: A0A4W6DN29
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

8187:aadacl4
gene id: 8187:aadacl4
uniprot id: A0A4W6EB79
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8187:LOC108875964
gene id: 8187:LOC108875964
uniprot id: A0A4W6BR45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8187:ggt1b
gene id: 8187:ggt1b
uniprot id: A0A4W6CKV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8187:rbm17
gene id: 8187:rbm17
uniprot id: A0A4W6FBI3
uniprot id: A0A4W6FBJ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

8187:slc2a11b
gene id: 8187:slc2a11b
uniprot id: A0A4W6GB88
uniprot id: A0A4W6GC65
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8187:LOC108875932
gene id: 8187:LOC108875932
uniprot id: A0A4W6FXG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8187:pgr
gene id: 8187:pgr
uniprot id: A0A4W6CFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:mtx2
gene id: 8187:mtx2
uniprot id: A0A4W6BNP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

8187:mmp14b
gene id: 8187:mmp14b
uniprot id: A0A4W6CPN4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8187:LOC108886452
gene id: 8187:LOC108886452
uniprot id: A0A4W6G083
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: dendrite
messages: sarcolemma
messages: synaptosome

8187:tmem200a
gene id: 8187:tmem200a
uniprot id: A0A4W6EUA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

8187:LOC108899637
gene id: 8187:LOC108899637
uniprot id: A0A4W6BU85
uniprot id: A0A4W6BUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

8187:exoc3
gene id: 8187:exoc3
uniprot id: A0A4W6DU34
names: Similarity
messages: Belongs to the SEC6 family.

8187:dnase2
gene id: 8187:dnase2
uniprot id: A0A4W6BMR7
names: Similarity
messages: Belongs to the DNase II family.

8187:pex2
gene id: 8187:pex2
uniprot id: A0A4W6FSI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

8187:yeats2
gene id: 8187:yeats2
uniprot id: A0A4W6E7N4
uniprot id: A0A4W6E8Z5
names: Subcellular Location Annotation
messages: Nucleus

8187:ebag9
gene id: 8187:ebag9
uniprot id: A0A4W6EAJ4
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

8187:si:dkey-247m21.3
gene id: 8187:si:dkey-247m21.3
uniprot id: A0A4W6BR05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

8187:gtf2f2b
gene id: 8187:gtf2f2b
uniprot id: A0A4W6FGS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

8187:smdt1b
gene id: 8187:smdt1b
uniprot id: A0A4W6FXQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8187:ptch2
gene id: 8187:ptch2
uniprot id: A0A4W6E2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

8187:tymp
gene id: 8187:tymp
uniprot id: A0A4W6D046
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Homodimer.

8187:LOC108901609
gene id: 8187:LOC108901609
uniprot id: A0A4W6CKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:tmem230b
gene id: 8187:tmem230b
uniprot id: A0A4W6G0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

8187:LOC108902169
gene id: 8187:LOC108902169
uniprot id: A0A4W6ECW2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8187:dgkb
gene id: 8187:dgkb
uniprot id: A0A4W6CNN3
uniprot id: A0A4W6CNR8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8187:LOC108876314
gene id: 8187:LOC108876314
uniprot id: A0A4W6F1P4
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

8187:zgc:153039
gene id: 8187:zgc:153039
uniprot id: A0A4W6BTX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8187:LOC108893542
gene id: 8187:LOC108893542
uniprot id: A0A4W6CVZ8
names: Subcellular Location Annotation
messages: Membrane

8187:pbx4
gene id: 8187:pbx4
uniprot id: A0A4W6FQE7
uniprot id: A0A4W6FR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8187:LOC108893913
gene id: 8187:LOC108893913
uniprot id: A0A4W6BV84
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8187:ddx6
gene id: 8187:ddx6
uniprot id: A0A4W6CBF8
names: Similarity
messages: Belongs to the DEAD box helicase family.

8187:psmd1
gene id: 8187:psmd1
uniprot id: A0A4W6DG94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

8187:mettl14
gene id: 8187:mettl14
uniprot id: A0A4W6BRU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MT-A70-like family.
messages: Heterodimer; heterodimerizes with mettl3 to form an antiparallel heterodimer that constitutes an active methyltransferase.
messages: Nucleus
messages: The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with mettl3, mettl14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing.

8187:LOC108902826
gene id: 8187:LOC108902826
uniprot id: A0A4W6G1C9
names: Similarity
messages: Belongs to the peptidase M14 family.

8187:gna11b
gene id: 8187:gna11b
uniprot id: A0A4W6DZS8
uniprot id: A0A4W6E231
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8187:cenpn
gene id: 8187:cenpn
uniprot id: A0A4W6C2N6
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

8187:LOC108886885
gene id: 8187:LOC108886885
uniprot id: A0A4W6DFW2
names: Subcellular Location Annotation
messages: extracellular space

8187:LOC108883660
gene id: 8187:LOC108883660
uniprot id: A0A4W6F516
names: Similarity
messages: Belongs to the peptidase C15 family.

8187:btg3
gene id: 8187:btg3
uniprot id: A0A4W6E6X9
names: Similarity
messages: Belongs to the BTG family.

8187:sesn1
gene id: 8187:sesn1
uniprot id: A0A4W6CFC8
uniprot id: A0A4W6CJA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

8187:ptgis
gene id: 8187:ptgis
uniprot id: A0A4W6D6S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8187:si:dkey-174m14.3
gene id: 8187:si:dkey-174m14.3
uniprot id: A0A4W6EG15
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108899720
gene id: 8187:LOC108899720
uniprot id: A0A4W6DER2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

8187:LOC108896499
gene id: 8187:LOC108896499
uniprot id: A0A4W6BV22
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

8187:LOC108878667
gene id: 8187:LOC108878667
uniprot id: A0A4W6G5E6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8187:ciao2a
gene id: 8187:ciao2a
uniprot id: A0A4W6FFK4
names: Similarity
messages: Belongs to the MIP18 family.

8187:kcnb2b
gene id: 8187:kcnb2b
uniprot id: A0A4W6E0E5
names: Subcellular Location Annotation
messages: Membrane
messages: Perikaryon
messages: dendrite

8187:bves
gene id: 8187:bves
uniprot id: A0A4W6EJW8
names: Similarity
messages: Belongs to the popeye family.

8187:rbm22
gene id: 8187:rbm22
uniprot id: A0A4W6C4S6
names: Similarity
messages: Belongs to the SLT11 family.

8187:nkain5
gene id: 8187:nkain5
uniprot id: A0A4W6E2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

8187:slc1a7a
gene id: 8187:slc1a7a
uniprot id: A0A4W6FQJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8187:dynll2a
gene id: 8187:dynll2a
uniprot id: A0A4W6DMB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8187:sox4a
gene id: 8187:sox4a
uniprot id: A0A4W6FJR5
names: Subcellular Location Annotation
messages: Nucleus

8187:stat3
gene id: 8187:stat3
uniprot id: A0A4W6CSA4
uniprot id: A0A4W6CSR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108886871
gene id: 8187:LOC108886871
uniprot id: A0A4W6DJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

8187:stk40
gene id: 8187:stk40
uniprot id: A0A4W6C141
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

8187:slc16a13
gene id: 8187:slc16a13
uniprot id: A0A4W6D319
names: Subcellular Location Annotation
messages: Membrane

8187:myo1eb
gene id: 8187:myo1eb
uniprot id: A0A4W6DIZ8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8187:LOC108883417
gene id: 8187:LOC108883417
uniprot id: A0A4W6D7V0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-97 and Arg-100) that bind to malonylated and succinylated substrates and define the specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

8187:pik3r1
gene id: 8187:pik3r1
uniprot id: A0A4W6CSG9
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

8187:nsun6
gene id: 8187:nsun6
uniprot id: A0A4W6FKF7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:gpsm1b
gene id: 8187:gpsm1b
uniprot id: A0A4W6CK46
names: Similarity
messages: Belongs to the GPSM family.

8187:mfsd14bb
gene id: 8187:mfsd14bb
uniprot id: A0A4W6DZL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8187:rps27l
gene id: 8187:rps27l
uniprot id: A0A4W6DDF9
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8187:npy8br
gene id: 8187:npy8br
uniprot id: A0A4W6F838
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:spopla
gene id: 8187:spopla
uniprot id: A0A4W6DGD0
names: Similarity
messages: Belongs to the Tdpoz family.

8187:golt1bb
gene id: 8187:golt1bb
uniprot id: A0A4W6F6Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

8187:imp3
gene id: 8187:imp3
uniprot id: A0A4W6FLF2
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

8187:si:ch211-213o11.11
gene id: 8187:si:ch211-213o11.11
uniprot id: A0A4W6D5D9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:LOC108878374
gene id: 8187:LOC108878374
uniprot id: A0A4W6FJF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

8187:il12bb
gene id: 8187:il12bb
uniprot id: A0A4W6F1I8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

8187:septin12
gene id: 8187:septin12
uniprot id: A0A4W6DY49
uniprot id: A0A4W6DYR9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8187:gpc2
gene id: 8187:gpc2
uniprot id: A0A4W6FBY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8187:fgf17
gene id: 8187:fgf17
uniprot id: A0A4W6G421
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8187:nsmce2
gene id: 8187:nsmce2
uniprot id: A0A4W6EH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

8187:pigw
gene id: 8187:pigw
uniprot id: A0A4W6ER46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

8187:LOC108891786
gene id: 8187:LOC108891786
uniprot id: A0A4W6FZG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8187:LOC108902971
gene id: 8187:LOC108902971
uniprot id: A0A4W6C206
names: Similarity
messages: Belongs to the globin family.

8187:LOC108894431
gene id: 8187:LOC108894431
uniprot id: A0A4W6FEW9
names: Similarity
messages: Belongs to the glutamine synthetase family.

8187:LOC108895879
gene id: 8187:LOC108895879
uniprot id: A0A4W6C110
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:cs
gene id: 8187:cs
uniprot id: F8SLH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

8187:atp8a2
gene id: 8187:atp8a2
uniprot id: A0A4W6DLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8187:nxph2a
gene id: 8187:nxph2a
uniprot id: A0A4W6DGB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8187:nlgn4xa
gene id: 8187:nlgn4xa
uniprot id: A0A4W6EE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8187:LOC108893852
gene id: 8187:LOC108893852
uniprot id: A0A4W6F9F6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:anapc10
gene id: 8187:anapc10
uniprot id: A0A4W6BUA6
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

8187:pdia4
gene id: 8187:pdia4
uniprot id: A0A4W6F942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8187:pde5ab
gene id: 8187:pde5ab
uniprot id: A0A4W6DK64
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8187:si:ch211-286o17.1
gene id: 8187:si:ch211-286o17.1
uniprot id: A0A4W6D533
names: Subcellular Location Annotation
messages: Membrane

8187:dlx6a
gene id: 8187:dlx6a
uniprot id: A0A4W6EJ56
names: Subcellular Location Annotation
messages: Nucleus

8187:ca5a
gene id: 8187:ca5a
uniprot id: A0A4W6EIC0
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8187:tmem177
gene id: 8187:tmem177
uniprot id: A0A4W6GBS9
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

8187:polr3k
gene id: 8187:polr3k
uniprot id: A0A4W6BXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

8187:LOC108902771
gene id: 8187:LOC108902771
uniprot id: A0A4W6C0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

8187:calb2a
gene id: 8187:calb2a
uniprot id: A0A4W6DWJ2
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

8187:tshz3b
gene id: 8187:tshz3b
uniprot id: A0A4W6D792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8187:slc25a34
gene id: 8187:slc25a34
uniprot id: A0A4W6ERA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:hoxb13a
gene id: 8187:hoxb13a
uniprot id: A0A4W6C2M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8187:pax5
gene id: 8187:pax5
uniprot id: A0A4W6BK98
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108897141
gene id: 8187:LOC108897141
uniprot id: A0A4W6E1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

8187:LOC108873843
gene id: 8187:LOC108873843
uniprot id: A0A4W6F240
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

8187:LOC108902303
gene id: 8187:LOC108902303
uniprot id: A0A4W6EHE5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8187:LOC108898142
gene id: 8187:LOC108898142
uniprot id: A0A4W6DYI7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

8187:aldoab
gene id: 8187:aldoab
uniprot id: A0A4W6G6D1
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

f2
gene id: 8187:il17a/f2
uniprot id: A0A4W6CRY3
names: Similarity
messages: Belongs to the IL-17 family.

8187:LOC108881189
gene id: 8187:LOC108881189
uniprot id: A0A4W6CE48
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108884397
gene id: 8187:LOC108884397
uniprot id: A0A4W6EV39
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

8187:rflna
gene id: 8187:rflna
uniprot id: A0A4W6FK80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8187:ovca2
gene id: 8187:ovca2
uniprot id: A0A4W6FN38
names: Similarity
messages: Belongs to the LovG family.

8187:LOC108902128
gene id: 8187:LOC108902128
uniprot id: A0A4W6E176
names: Subcellular Location Annotation
messages: extracellular space

8187:ccl25a
gene id: 8187:ccl25a
uniprot id: A0A4W6ECM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8187:mccc2
gene id: 8187:mccc2
uniprot id: A0A4W6EVG5
names: Similarity
messages: Belongs to the AccD/PCCB family.

8187:katnal1
gene id: 8187:katnal1
uniprot id: A0A4W6DAQ2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

8187:LOC108889245
gene id: 8187:LOC108889245
uniprot id: A0A4W6EP59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8187:gnb5b
gene id: 8187:gnb5b
uniprot id: A0A4W6FI31
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8187:sod1
gene id: 8187:sod1
uniprot id: A0A4W6FVB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

8187:LOC108876695
gene id: 8187:LOC108876695
uniprot id: A0A4W6CXS2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8187:slc5a3b
gene id: 8187:slc5a3b
uniprot id: A0A4W6CIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8187:foxo3b
gene id: 8187:foxo3b
uniprot id: A0A4W6CJ67
names: Subcellular Location Annotation
messages: Nucleus

8187:snf8
gene id: 8187:snf8
uniprot id: A0A4W6E1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

8187:tmem38a
gene id: 8187:tmem38a
uniprot id: A0A4W6CH86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

8187:rpl5a
gene id: 8187:rpl5a
uniprot id: A0A4W6FF17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

8187:abl1
gene id: 8187:abl1
uniprot id: A0A4W6CJD3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8187:LOC108880449
gene id: 8187:LOC108880449
uniprot id: A0A4W6FE09
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8187:gusb
gene id: 8187:gusb
uniprot id: A0A4W6EPK6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homotetramer.
messages: Inhibited by L-aspartic acid.
messages: Lysosome
messages: Plays an important role in the degradation of dermatan and keratan sulfates.

8187:ngb
gene id: 8187:ngb
uniprot id: A0A4W6F1Y7
names: Similarity
messages: Belongs to the globin family.

8187:hcrt
gene id: 8187:hcrt
uniprot id: A0A4W6CTP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

8187:rell2
gene id: 8187:rell2
uniprot id: A0A4W6E1X8
names: Similarity
messages: Belongs to the RELT family.

8187:ftsj3
gene id: 8187:ftsj3
uniprot id: A0A4W6FC86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

8187:sap130a
gene id: 8187:sap130a
uniprot id: A0A4W6DGN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

8187:khdc4
gene id: 8187:khdc4
uniprot id: A0A4W6FNR5
names: Similarity
messages: Belongs to the KHDC4 family.

8187:tmem63c
gene id: 8187:tmem63c
uniprot id: A0A4W6F4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

8187:rps12
gene id: 8187:rps12
uniprot id: A0A4W6E443
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

8187:slc25a55a
gene id: 8187:slc25a55a
uniprot id: A0A4W6CJ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:sin3b
gene id: 8187:sin3b
uniprot id: A0A4W6FSQ4
names: Subcellular Location Annotation
messages: Nucleus

8187:trim32
gene id: 8187:trim32
uniprot id: A0A4W6CLM6
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8187:eloal
gene id: 8187:eloal
uniprot id: A0A4W6DY40
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108885884
gene id: 8187:LOC108885884
uniprot id: A0A4W6CXH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8187:LOC108888552
gene id: 8187:LOC108888552
uniprot id: A0A4W6FLR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

8187:mettl6
gene id: 8187:mettl6
uniprot id: A0A4W6BMF2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

8187:si:ch211-136a13.1
gene id: 8187:si:ch211-136a13.1
uniprot id: A0A4W6D2C1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108902698
gene id: 8187:LOC108902698
uniprot id: A0A4W6FZZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8187:hpdl
gene id: 8187:hpdl
uniprot id: A0A4W6F745
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

8187:snx17
gene id: 8187:snx17
uniprot id: A0A4W6E3B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8187:LOC108897293
gene id: 8187:LOC108897293
uniprot id: A0A4W6CPI0
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

8187:LOC108888303
gene id: 8187:LOC108888303
uniprot id: A0A4W6CG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

8187:ccr9a
gene id: 8187:ccr9a
uniprot id: A0A4W6CLG0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:LOC108884886
gene id: 8187:LOC108884886
uniprot id: A0A4W6CH28
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8187:zgc:112294
gene id: 8187:zgc:112294
uniprot id: A0A4W6EB69
names: Subcellular Location Annotation
messages: Membrane

8187:hpn
gene id: 8187:hpn
uniprot id: A0A4W6EEL3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8187:LOC108875665
gene id: 8187:LOC108875665
uniprot id: A0A4W6F480
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8187:prr5a
gene id: 8187:prr5a
uniprot id: A0A4W6DXW1
names: Similarity
messages: Belongs to the PROTOR family.

8187:cops5
gene id: 8187:cops5
uniprot id: A0A4W6DSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

8187:rragd
gene id: 8187:rragd
uniprot id: A0A4W6BTF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

8187:sh3gl1b
gene id: 8187:sh3gl1b
uniprot id: A0A4W6FVA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8187:kcnn1a
gene id: 8187:kcnn1a
uniprot id: A0A4W6FCR7
names: Subcellular Location Annotation
messages: Membrane

8187:usp39
gene id: 8187:usp39
uniprot id: A0A4W6GCI9
names: Subcellular Location Annotation
messages: Nucleus

8187:tmem106ba
gene id: 8187:tmem106ba
uniprot id: A0A4W6CRH5
names: Similarity
messages: Belongs to the TMEM106 family.

8187:shrprbck1r
gene id: 8187:shrprbck1r
uniprot id: A0A4W6F989
names: Similarity
messages: Belongs to the RBR family.

8187:tspan4a
gene id: 8187:tspan4a
uniprot id: A0A4W6EQR1
uniprot id: A0A4W6EQS0
uniprot id: A0A4W6ERM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8187:pdss2
gene id: 8187:pdss2
uniprot id: A0A4W6FCE0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8187:rogdi
gene id: 8187:rogdi
uniprot id: A0A4W6D3Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Presynapse
messages: Vesicle
messages: synaptic vesicle

8187:LOC108889595
gene id: 8187:LOC108889595
uniprot id: A0A4W6CE02
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome

8187:nampt1
gene id: 8187:nampt1
uniprot id: A0A4W6D5V6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

8187:coro1cb
gene id: 8187:coro1cb
uniprot id: A0A4W6CPZ9
names: Similarity
messages: Belongs to the WD repeat coronin family.

8187:atp8b1
gene id: 8187:atp8b1
uniprot id: A0A4W6CSM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8187:LOC108897206
gene id: 8187:LOC108897206
uniprot id: A0A4W6FBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

8187:fis1
gene id: 8187:fis1
uniprot id: A0A4W6CNT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

8187:sec24a
gene id: 8187:sec24a
uniprot id: A0A4W6DTB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8187:LOC108900104
gene id: 8187:LOC108900104
uniprot id: A0A4W6CXC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8187:si:ch211-255i20.3
gene id: 8187:si:ch211-255i20.3
uniprot id: A0A4W6EEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108876679
gene id: 8187:LOC108876679
uniprot id: A0A4W6D298
names: Subcellular Location Annotation
messages: Membrane

8187:bri3
gene id: 8187:bri3
uniprot id: A0A4W6DUS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

8187:cacna2d3a
gene id: 8187:cacna2d3a
uniprot id: A0A4W6F0K8
uniprot id: A0A4W6F1R4
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

8187:chrm5a
gene id: 8187:chrm5a
uniprot id: A0A4W6EVB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8187:LOC108890244
gene id: 8187:LOC108890244
uniprot id: A0A4W6CRK1
names: Subcellular Location Annotation
messages: extracellular space

8187:thrb
gene id: 8187:thrb
uniprot id: A0A4W6C6I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8187:npffr1l2
gene id: 8187:npffr1l2
uniprot id: A0A4W6ELB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8187:LOC108884995
gene id: 8187:LOC108884995
uniprot id: A0A4W6FSR0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8187:trappc2l
gene id: 8187:trappc2l
uniprot id: A0A4W6CIT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

8187:aldoca
gene id: 8187:aldoca
uniprot id: A0A4W6DM73
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

8187:pparg
gene id: 8187:pparg
uniprot id: A0A4W6F2X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8187:ankrd13a
gene id: 8187:ankrd13a
uniprot id: A0A4W6GCA9
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8187:LOC108876174
gene id: 8187:LOC108876174
uniprot id: A0A4W6CVX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:LOC108893651
gene id: 8187:LOC108893651
uniprot id: A0A4W6FNQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8187:sdc2
gene id: 8187:sdc2
uniprot id: A0A4W6DQ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8187:tmed6
gene id: 8187:tmed6
uniprot id: A0A4W6ED89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:LOC108874933
gene id: 8187:LOC108874933
uniprot id: A0A4W6DY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8187:LOC108893962
gene id: 8187:LOC108893962
uniprot id: A0A4W6FW14
names: Similarity
messages: Belongs to the CNKSR family.

8187:LOC108883856
gene id: 8187:LOC108883856
uniprot id: A0A4W6C2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8187:si:ch211-264f5.6
gene id: 8187:si:ch211-264f5.6
uniprot id: A0A4W6CJP1
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108883132
gene id: 8187:LOC108883132
uniprot id: A0A4W6G137
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8187:gdpgp1
gene id: 8187:gdpgp1
uniprot id: A0A4W6EH37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

8187:csrnp3
gene id: 8187:csrnp3
uniprot id: A0A4W6FIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8187:LOC108898915
gene id: 8187:LOC108898915
uniprot id: A0A4W6DSD7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8187:lmod2b
gene id: 8187:lmod2b
uniprot id: A0A4W6BNI3
names: Subcellular Location Annotation
messages: cytoskeleton

8187:mdm4
gene id: 8187:mdm4
uniprot id: A0A4W6DL51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Nucleus

8187:olfml2bb
gene id: 8187:olfml2bb
uniprot id: A0A4W6E8L2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:mapk1
gene id: 8187:mapk1
uniprot id: A0A4W6FKA8
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8187:slc5a2
gene id: 8187:slc5a2
uniprot id: A0A4W6DL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8187:LOC108885058
gene id: 8187:LOC108885058
uniprot id: A0A4W6G5G6
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108902551
gene id: 8187:LOC108902551
uniprot id: A0A4W6D0I7
uniprot id: A0A4W6D0K5
names: Similarity
messages: Belongs to the RCAN family.

8187:ing4
gene id: 8187:ing4
uniprot id: A0A4W6DCA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8187:eef1da
gene id: 8187:eef1da
uniprot id: A0A4W6BT81
uniprot id: A0A4W6BT86
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

8187:LOC108873508
gene id: 8187:LOC108873508
uniprot id: A0A4W6EII2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8187:pals1b
gene id: 8187:pals1b
uniprot id: A0A4W6EHS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

8187:tent5aa
gene id: 8187:tent5aa
uniprot id: A0A4W6E9V9
names: Similarity
messages: Belongs to the TENT family.

8187:psmb2
gene id: 8187:psmb2
uniprot id: A0A4W6F912
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8187:cldn29
gene id: 8187:cldn29
uniprot id: A0A4W6FQN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:copg2
gene id: 8187:copg2
uniprot id: A0A4W6BVE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

8187:cfdp1
gene id: 8187:cfdp1
uniprot id: A0A4W6FT73
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

8187:basp1
gene id: 8187:basp1
uniprot id: A0A4W6CCZ9
names: Similarity
messages: Belongs to the BASP1 family.

8187:lft1
gene id: 8187:lft1
uniprot id: A0A4W6CB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8187:tmem106bb
gene id: 8187:tmem106bb
uniprot id: A0A4W6CEK6
names: Similarity
messages: Belongs to the TMEM106 family.

8187:LOC108892133
gene id: 8187:LOC108892133
uniprot id: A0A4W6DSJ5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:chac2
gene id: 8187:chac2
uniprot id: A0A4W6FF94
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

8187:saraf
gene id: 8187:saraf
uniprot id: A0A4W6F6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8187:higd2a
gene id: 8187:higd2a
uniprot id: A0A4W6DBG6
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

8187:fgf1a
gene id: 8187:fgf1a
uniprot id: A0A4W6E6H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

8187:wls
gene id: 8187:wls
uniprot id: A0A4W6FDN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

8187:cpeb4b
gene id: 8187:cpeb4b
uniprot id: A0A4W6EZ14
uniprot id: A0A4W6EZQ2
names: Similarity
messages: Belongs to the RRM CPEB family.

8187:LOC108883592
gene id: 8187:LOC108883592
uniprot id: A0A4W6E948
names: Subcellular Location Annotation
messages: Membrane

8187:tmem59l
gene id: 8187:tmem59l
uniprot id: A0A4W6FS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

8187:mgat2
gene id: 8187:mgat2
uniprot id: A0A4W6F2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

8187:ptges3l
gene id: 8187:ptges3l
uniprot id: A0A4W6DJM1
names: Similarity
messages: Belongs to the p23/wos2 family.

8187:qtrt1
gene id: 8187:qtrt1
uniprot id: A0A4W6FYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane

8187:LOC108887885
gene id: 8187:LOC108887885
uniprot id: A0A4W6BUY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:stac3
gene id: 8187:stac3
uniprot id: A0A4W6BSL3
names: Subcellular Location Annotation
messages: sarcolemma

8187:LOC108875476
gene id: 8187:LOC108875476
uniprot id: A0A4W6FAI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8187:immp2l
gene id: 8187:immp2l
uniprot id: A0A4W6FDV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

8187:usp4
gene id: 8187:usp4
uniprot id: A0A4W6F399
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:dyrk1ab
gene id: 8187:dyrk1ab
uniprot id: A0A4W6FG04
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8187:mcm7
gene id: 8187:mcm7
uniprot id: A0A4W6FBW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

8187:LOC108892923
gene id: 8187:LOC108892923
uniprot id: A0A4W6EW18
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

8187:dmc1
gene id: 8187:dmc1
uniprot id: A0A4W6BKG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. DMC1 subfamily.
messages: May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
messages: Nucleus

8187:grhpra
gene id: 8187:grhpra
uniprot id: A0A4W6C672
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8187:pck1
gene id: 8187:pck1
uniprot id: A0A4W6EXU3
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

8187:kdr
gene id: 8187:kdr
uniprot id: A0A4W6CK86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8187:thumpd3
gene id: 8187:thumpd3
uniprot id: A0A4W6G0Q0
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8187:epor
gene id: 8187:epor
uniprot id: A0A4W6EAY5
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.

8187:prmt5
gene id: 8187:prmt5
uniprot id: A0A4W6CT50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

8187:lrig1
gene id: 8187:lrig1
uniprot id: A0A4W6FDW0
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108884694
gene id: 8187:LOC108884694
uniprot id: A0A4W6DBU2
uniprot id: A0A4W6DDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

8187:LOC108889222
gene id: 8187:LOC108889222
uniprot id: A0A4W6G539
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8187:LOC108890492
gene id: 8187:LOC108890492
uniprot id: A0A4W6EEU8
names: Similarity
messages: Belongs to the cyclin family.

8187:fermt3b
gene id: 8187:fermt3b
uniprot id: A0A4W6F0A8
names: Similarity
messages: Belongs to the kindlin family.

8187:LOC108887353
gene id: 8187:LOC108887353
uniprot id: A0A4W6DGL3
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108889657
gene id: 8187:LOC108889657
uniprot id: A0A4W6D054
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

8187:LOC108876175
gene id: 8187:LOC108876175
uniprot id: A0A4W6CVC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8187:npy4r
gene id: 8187:npy4r
uniprot id: A0A4W6DWL9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:ppm1lb
gene id: 8187:ppm1lb
uniprot id: A0A4W6BVF1
names: Similarity
messages: Belongs to the PP2C family.

8187:LOC108893234
gene id: 8187:LOC108893234
uniprot id: A0A4W6CVZ1
names: Subcellular Location Annotation
messages: Membrane

8187:esama
gene id: 8187:esama
uniprot id: A0A4W6DWA1
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108891199
gene id: 8187:LOC108891199
uniprot id: A0A4W6GAS3
names: Subcellular Location Annotation
messages: Nucleus

8187:hoxc12a
gene id: 8187:hoxc12a
uniprot id: A0A4W6FLG4
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108881285
gene id: 8187:LOC108881285
uniprot id: A0A4W6F8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Photoreceptor outer segment membrane

8187:asf1ba
gene id: 8187:asf1ba
uniprot id: A0A4W6FZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

8187:eva1a
gene id: 8187:eva1a
uniprot id: A0A4W6G206
names: Similarity
messages: Belongs to the EVA1 family.

8187:chmp5a
gene id: 8187:chmp5a
uniprot id: A0A4W6F4C6
names: Similarity
messages: Belongs to the SNF7 family.

8187:LOC108872939
gene id: 8187:LOC108872939
uniprot id: A0A4W6C0V4
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

8187:gabbr1a
gene id: 8187:gabbr1a
uniprot id: A0A4W6BV40
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:LOC108876604
gene id: 8187:LOC108876604
uniprot id: A0A4W6DSS4
names: Similarity
messages: Belongs to the nanos family.

8187:LOC108874151
gene id: 8187:LOC108874151
uniprot id: A0A4W6F087
names: Subcellular Location Annotation
messages: Cytoplasm

8187:rdh1
gene id: 8187:rdh1
uniprot id: A0A4W6FJR8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8187:mrpl2
gene id: 8187:mrpl2
uniprot id: A0A4W6C761
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

8187:LOC108900464
gene id: 8187:LOC108900464
uniprot id: A0A4W6E840
names: Similarity
messages: Belongs to the OSBP family.

8187:zgc:92313
gene id: 8187:zgc:92313
uniprot id: A0A4W6G664
names: Subcellular Location Annotation
messages: extracellular space

8187:cmklr1
gene id: 8187:cmklr1
uniprot id: A0A4W6G9W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8187:cct8
gene id: 8187:cct8
uniprot id: A0A4W6D9F8
uniprot id: A0A4W6DA67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

8187:irx6a
gene id: 8187:irx6a
uniprot id: A0A4W6EFA2
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108884290
gene id: 8187:LOC108884290
uniprot id: A0A4W6BRM4
names: Subcellular Location Annotation
messages: Inflammasome
messages: cytosol

8187:spi1a
gene id: 8187:spi1a
uniprot id: A0A4W6D8H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:tlx2
gene id: 8187:tlx2
uniprot id: A0A4W6BVT7
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108882140
gene id: 8187:LOC108882140
uniprot id: A0A4W6DM98
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

8187:kif7
gene id: 8187:kif7
uniprot id: A0A4W6C795
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8187:smpx
gene id: 8187:smpx
uniprot id: A0A4W6BRH0
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

8187:ddah1
gene id: 8187:ddah1
uniprot id: A0A4W6FNR0
uniprot id: A0A4W6FP59
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

8187:LOC108891705
gene id: 8187:LOC108891705
uniprot id: A0A4W6G4Y4
names: Subcellular Location Annotation
messages: Membrane

8187:c5ar1
gene id: 8187:c5ar1
uniprot id: A0A4W6G2G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8187:mustn1a
gene id: 8187:mustn1a
uniprot id: A0A4W6EIN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

8187:rps10
gene id: 8187:rps10
uniprot id: A0A4W6D8H2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

8187:sfrp5
gene id: 8187:sfrp5
uniprot id: A0A4W6CC09
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:kynu
gene id: 8187:kynu
uniprot id: A0A4W6ETL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108893179
gene id: 8187:LOC108893179
uniprot id: A0A4W6EIT3
names: Subcellular Location Annotation
messages: Membrane

8187:kcnab2a
gene id: 8187:kcnab2a
uniprot id: A0A4W6FMA9
uniprot id: A0A4W6FPI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

8187:pax6b
gene id: 8187:pax6b
uniprot id: A0A4W6CFF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8187:grpel1
gene id: 8187:grpel1
uniprot id: A0A4W6DFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

8187:mri1
gene id: 8187:mri1
uniprot id: A0A4W6CI56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

8187:cebp1
gene id: 8187:cebp1
uniprot id: A0A4W6C6J2
names: Similarity
messages: Belongs to the bZIP family. C/EBP subfamily.

8187:dusp1
gene id: 8187:dusp1
uniprot id: A0A4W6DFT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8187:cdpf1
gene id: 8187:cdpf1
uniprot id: A0A4W6FLH0
names: Similarity
messages: Belongs to the CDPF1 family.

8187:dipk1aa
gene id: 8187:dipk1aa
uniprot id: A0A4W6FDG6
names: Similarity
messages: Belongs to the DIPK family.

8187:crygmx
gene id: 8187:crygmx
uniprot id: A0A4W6BVK0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:LOC108903056
gene id: 8187:LOC108903056
uniprot id: A0A4W6CVD3
uniprot id: A0A4W6EP69
names: Similarity
messages: Belongs to the CDV3 family.

8187:gper1
gene id: 8187:gper1
uniprot id: A0A4W6BXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:mmp15b
gene id: 8187:mmp15b
uniprot id: A0A4W6FZC9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8187:LOC108876096
gene id: 8187:LOC108876096
uniprot id: A0A4W6DRP9
names: Subcellular Location Annotation
messages: Mitochondrion

8187:pfdn2
gene id: 8187:pfdn2
uniprot id: A0A4W6DTA4
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

8187:LOC108888505
gene id: 8187:LOC108888505
uniprot id: A0A4W6F343
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

8187:egfra
gene id: 8187:egfra
uniprot id: A0A4W6C3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8187:LOC108883731
gene id: 8187:LOC108883731
uniprot id: A0A4W6FIQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

8187:onecutl
gene id: 8187:onecutl
uniprot id: A0A4W6C6Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8187:gnrhr4
gene id: 8187:gnrhr4
uniprot id: A0A4W6CKF4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:LOC108885897
gene id: 8187:LOC108885897
uniprot id: A0A4W6FPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

8187:zgc:109889
gene id: 8187:zgc:109889
uniprot id: A0A4W6CGA6
uniprot id: A0A4W6CJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8187:clgn
gene id: 8187:clgn
uniprot id: A0A4W6DFA2
names: Similarity
messages: Belongs to the calreticulin family.

8187:mbtps2
gene id: 8187:mbtps2
uniprot id: A0A4W6BQQ1
names: Similarity
messages: Belongs to the peptidase M50A family.

8187:plcd4b
gene id: 8187:plcd4b
uniprot id: A0A4W6FEX0
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

8187:mfsd8l1
gene id: 8187:mfsd8l1
uniprot id: A0A4W6D8J1
names: Subcellular Location Annotation
messages: Membrane

8187:rdh8a
gene id: 8187:rdh8a
uniprot id: A0A4W6FY06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

8187:eif3jb
gene id: 8187:eif3jb
uniprot id: A0A4W6F1I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8187:efnb3b
gene id: 8187:efnb3b
uniprot id: A0A4W6E8M7
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:clptm1
gene id: 8187:clptm1
uniprot id: A0A4W6CMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

8187:gal
gene id: 8187:gal
uniprot id: A0A4W6FRD1
uniprot id: A0A4W6FT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

8187:grnb
gene id: 8187:grnb
uniprot id: A0A4W6E7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8187:itpka
gene id: 8187:itpka
uniprot id: A0A4W6FER2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8187:saa
gene id: 8187:saa
uniprot id: A0A4W6D066
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

8187:clcn7
gene id: 8187:clcn7
uniprot id: A0A4W6CA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

8187:klhl3
gene id: 8187:klhl3
uniprot id: A0A4W6FZS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KLHL3 family.
messages: cytoskeleton
messages: cytosol

8187:cfl1
gene id: 8187:cfl1
uniprot id: A0A4W6EYY4
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8187:dgat1b
gene id: 8187:dgat1b
uniprot id: A0A4W6CMT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

8187:LOC108894190
gene id: 8187:LOC108894190
uniprot id: A0A4W6FVI4
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

8187:nmur3
gene id: 8187:nmur3
uniprot id: A0A4W6DKQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

8187:LOC108883430
gene id: 8187:LOC108883430
uniprot id: A0A4W6DAJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8187:pou4f3
gene id: 8187:pou4f3
uniprot id: A0A4W6EY14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8187:ccnb1
gene id: 8187:ccnb1
uniprot id: A0A4W6FDW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8187:pcsk7
gene id: 8187:pcsk7
uniprot id: A0A4W6DSR2
names: Similarity
messages: Belongs to the peptidase S8 family.

8187:tcf7l2
gene id: 8187:tcf7l2
uniprot id: A0A4W6BYL2
uniprot id: A0A4W6C1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8187:adra1aa
gene id: 8187:adra1aa
uniprot id: A0A4W6G0F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:tcp11l2
gene id: 8187:tcp11l2
uniprot id: A0A4W6E462
names: Similarity
messages: Belongs to the TCP11 family.

8187:LOC108887834
gene id: 8187:LOC108887834
uniprot id: A0A4W6ERN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8187:zgc:110158
gene id: 8187:zgc:110158
uniprot id: A0A4W6E532
names: Subcellular Location Annotation
messages: Nucleus

8187:rpl37a
gene id: 8187:rpl37a
uniprot id: A0A4W6C5B9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

8187:LOC108877981
gene id: 8187:LOC108877981
uniprot id: A0A4W6G1R9
names: Similarity
messages: Belongs to the VPS26 family.

8187:pptc7a
gene id: 8187:pptc7a
uniprot id: A0A4W6G7U9
names: Similarity
messages: Belongs to the PP2C family.

8187:antkmt
gene id: 8187:antkmt
uniprot id: A0A4W6ETW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

8187:vsig10l
gene id: 8187:vsig10l
uniprot id: A0A4W6C0H2
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108890208
gene id: 8187:LOC108890208
uniprot id: A0A4W6FTQ9
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8187:lmbr1l
gene id: 8187:lmbr1l
uniprot id: A0A4W6FA44
names: Similarity
messages: Belongs to the LIMR family.

8187:akt1
gene id: 8187:akt1
uniprot id: A0A4W6DTD9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8187:u2af2a
gene id: 8187:u2af2a
uniprot id: A0A4W6D851
uniprot id: A0A4W6D8F0
uniprot id: A0A4W6D8R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

8187:nr1h3
gene id: 8187:nr1h3
uniprot id: A0A4W6EML4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8187:atxn1a
gene id: 8187:atxn1a
uniprot id: A0A4W6DWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

8187:zranb1b
gene id: 8187:zranb1b
uniprot id: A0A4W6DKU4
names: Similarity
messages: Belongs to the peptidase C64 family.

8187:peli3
gene id: 8187:peli3
uniprot id: A0A4W6DJV6
names: Similarity
messages: Belongs to the pellino family.

8187:mst1rb
gene id: 8187:mst1rb
uniprot id: A0A4W6EPZ4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:wdpcp
gene id: 8187:wdpcp
uniprot id: A0A4W6DU82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

8187:wapla
gene id: 8187:wapla
uniprot id: A0A4W6EPB0
names: Similarity
messages: Belongs to the WAPL family.

8187:LOC108897494
gene id: 8187:LOC108897494
uniprot id: A0A4W6DGY0
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8187:gda
gene id: 8187:gda
uniprot id: A0A4W6G8V1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

8187:clpp
gene id: 8187:clpp
uniprot id: A0A4W6E0X6
names: Similarity
messages: Belongs to the peptidase S14 family.

8187:lg16 lg22h10orf53
gene id: 8187:lg16_lg22h10orf53
uniprot id: A0A4W6E9V1
names: Similarity
messages: Belongs to the UPF0728 family.

8187:cnpy2
gene id: 8187:cnpy2
uniprot id: A0A4W6FV28
names: Similarity
messages: Belongs to the canopy family.

8187:bet1
gene id: 8187:bet1
uniprot id: A0A4W6END6
names: Subcellular Location Annotation
messages: Membrane

8187:tshz3a
gene id: 8187:tshz3a
uniprot id: A0A4W6EW81
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

8187:lrp12
gene id: 8187:lrp12
uniprot id: A0A4W6DVX6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:plaua
gene id: 8187:plaua
uniprot id: A0A4W6DVC9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8187:rnf121
gene id: 8187:rnf121
uniprot id: A0A4W6FV77
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108883793
gene id: 8187:LOC108883793
uniprot id: A0A4W6FNP4
names: Similarity
messages: Belongs to the BRINP family.

8187:LOC108893889
gene id: 8187:LOC108893889
uniprot id: A0A4W6FHC1
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108898754
gene id: 8187:LOC108898754
uniprot id: A0A4W6DHT2
names: Similarity
messages: Belongs to the ZC3H12 family.

8187:LOC108897551
gene id: 8187:LOC108897551
uniprot id: A0A4W6F757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

8187:LOC108888595
gene id: 8187:LOC108888595
uniprot id: A0A4W6DUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8187:laptm4b
gene id: 8187:laptm4b
uniprot id: A0A4W6DW72
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

8187:nup210
gene id: 8187:nup210
uniprot id: A0A4W6EM41
names: Similarity
messages: Belongs to the NUP210 family.

8187:spata18
gene id: 8187:spata18
uniprot id: A0A4W6EEC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

8187:pycr3
gene id: 8187:pycr3
uniprot id: A0A4W6FBN7
uniprot id: A0A4W6FCK5
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8187:med9
gene id: 8187:med9
uniprot id: A0A4W6G7P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8187:ets1
gene id: 8187:ets1
uniprot id: A0A4W6CVL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:cspg4ba
gene id: 8187:cspg4ba
uniprot id: A0A4W6BK22
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:gabrr3a
gene id: 8187:gabrr3a
uniprot id: A0A4W6CWL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:tor2a
gene id: 8187:tor2a
uniprot id: A0A4W6CRH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

8187:rab27a
gene id: 8187:rab27a
uniprot id: A0A4W6BXF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8187:tp73
gene id: 8187:tp73
uniprot id: A0A4W6G5W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

8187:bace2
gene id: 8187:bace2
uniprot id: A0A4W6CSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Endosome
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

8187:acp1
gene id: 8187:acp1
uniprot id: A0A4W6DBK5
uniprot id: A0A4W6DBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

8187:dus4l
gene id: 8187:dus4l
uniprot id: A0A4W6D2Q5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

8187:esamb
gene id: 8187:esamb
uniprot id: A0A4W6FN81
names: Subcellular Location Annotation
messages: Membrane

8187:loxa
gene id: 8187:loxa
uniprot id: A0A4W6C8D1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8187:rfx3
gene id: 8187:rfx3
uniprot id: A0A4W6CN79
names: Subcellular Location Annotation
messages: Nucleus

8187:grik2
gene id: 8187:grik2
uniprot id: A0A4W6ELV0
uniprot id: A0A4W6ELZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8187:entpd4
gene id: 8187:entpd4
uniprot id: A0A4W6G8U7
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8187:trak1a
gene id: 8187:trak1a
uniprot id: A0A4W6EDU8
uniprot id: A0A4W6EF03
uniprot id: A0A4W6EF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

8187:sostdc1a
gene id: 8187:sostdc1a
uniprot id: A0A4W6CJ60
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:smx5
gene id: 8187:smx5
uniprot id: A0A4W6DKR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

8187:LOC108878770
gene id: 8187:LOC108878770
uniprot id: A0A4W6GAV9
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8187:arr3a
gene id: 8187:arr3a
uniprot id: A0A4W6EY69
names: Similarity
messages: Belongs to the arrestin family.

8187:LOC108885384
gene id: 8187:LOC108885384
uniprot id: A0A4W6D4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

8187:itfg1
gene id: 8187:itfg1
uniprot id: A0A4W6G1A1
names: Similarity
messages: Belongs to the TIP family.

8187:lhfpl4a
gene id: 8187:lhfpl4a
uniprot id: A0A4W6D9S8
names: Subcellular Location Annotation
messages: Membrane

8187:gpc4
gene id: 8187:gpc4
uniprot id: A0A4W6FRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8187:akr1a1b
gene id: 8187:akr1a1b
uniprot id: A0A4W6F0W6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8187:pdgfrl
gene id: 8187:pdgfrl
uniprot id: A0A4W6BUW4
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

8187:LOC108881904
gene id: 8187:LOC108881904
uniprot id: A0A4W6F0E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8187:sntg1
gene id: 8187:sntg1
uniprot id: A0A4W6CAH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

8187:LOC108876063
gene id: 8187:LOC108876063
uniprot id: A0A4W6E0J2
uniprot id: A0A4W6E370
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8187:septin2
gene id: 8187:septin2
uniprot id: A0A4W6FH79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

8187:rpa2
gene id: 8187:rpa2
uniprot id: A0A4W6DH70
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

8187:zmp:0000001167
gene id: 8187:zmp:0000001167
uniprot id: A0A4W6DYL9
uniprot id: A0A4W6DYM1
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

8187:LOC108901179
gene id: 8187:LOC108901179
uniprot id: A0A4W6DN09
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8187:zgc:101559
gene id: 8187:zgc:101559
uniprot id: A0A4W6DAC5
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8187:tomm5
gene id: 8187:tomm5
uniprot id: A0A4W6C762
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

8187:smim7
gene id: 8187:smim7
uniprot id: A0A4W6CHF6
names: Similarity
messages: Belongs to the SMIM7 family.

8187:cdkn2aipnl
gene id: 8187:cdkn2aipnl
uniprot id: A0A4W6DS60
names: Similarity
messages: Belongs to the CARF family.

8187:inka1b
gene id: 8187:inka1b
uniprot id: A0A4W6CZF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8187:eif4e1c
gene id: 8187:eif4e1c
uniprot id: A0A4W6C5E1
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8187:clrn2
gene id: 8187:clrn2
uniprot id: A0A4W6EMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

8187:senp8
gene id: 8187:senp8
uniprot id: A0A4W6F518
names: Similarity
messages: Belongs to the peptidase C48 family.

8187:hsd3b7
gene id: 8187:hsd3b7
uniprot id: A0A4W6CJ26
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8187:LOC108881619
gene id: 8187:LOC108881619
uniprot id: A0A4W6CQ57
names: Similarity
messages: Belongs to the EEIG family.

8187:arl8
gene id: 8187:arl8
uniprot id: A0A4W6FHN9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8187:cltrn
gene id: 8187:cltrn
uniprot id: A0A4W6E2L1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:proca
gene id: 8187:proca
uniprot id: A0A4W6CLJ3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8187:LOC108901717
gene id: 8187:LOC108901717
uniprot id: A0A4W6BV31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8187:zfp36l2
gene id: 8187:zfp36l2
uniprot id: A0A4W6FYK9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8187:tbcc
gene id: 8187:tbcc
uniprot id: A0A4W6DZD9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

8187:crata
gene id: 8187:crata
uniprot id: A0A4W6F6I4
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8187:fah
gene id: 8187:fah
uniprot id: A0A4W6D2S8
names: Similarity
messages: Belongs to the FAH family.

8187:LOC108880002
gene id: 8187:LOC108880002
uniprot id: A0A4W6CT81
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

8187:nkx6.1
gene id: 8187:nkx6.1
uniprot id: A0A4W6ELZ1
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108878948
gene id: 8187:LOC108878948
uniprot id: A0A4W6E1R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

8187:keap1b
gene id: 8187:keap1b
uniprot id: A0A4W6FU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

8187:tm9sf2
gene id: 8187:tm9sf2
uniprot id: A0A4W6BWY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8187:tex10
gene id: 8187:tex10
uniprot id: A0A4W6CE74
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

8187:atp6v1ab
gene id: 8187:atp6v1ab
uniprot id: A0A4W6DLX3
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

8187:svopa
gene id: 8187:svopa
uniprot id: A0A4W6GAM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8187:LOC108880818
gene id: 8187:LOC108880818
uniprot id: A0A4W6EXJ2
names: Similarity
messages: Belongs to the FAM83 family.

8187:tada1
gene id: 8187:tada1
uniprot id: A0A4W6BXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

8187:ogfod1
gene id: 8187:ogfod1
uniprot id: A0A4W6BY52
names: Similarity
messages: Belongs to the TPA1 family.

8187:adgra2
gene id: 8187:adgra2
uniprot id: A0A4W6G5X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

8187:nrxn2a
gene id: 8187:nrxn2a
uniprot id: A0A4W6D463
uniprot id: A0A4W6D4A4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:eif4a2
gene id: 8187:eif4a2
uniprot id: A0A4W6FMX3
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8187:KEG24 p04
gene id: 8187:KEG24_p04
uniprot id: Q3IA67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

8187:acadvl
gene id: 8187:acadvl
uniprot id: A0A4W6EFI6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8187:ca8
gene id: 8187:ca8
uniprot id: A0A4W6CPB7
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

8187:gal3st4
gene id: 8187:gal3st4
uniprot id: A0A4W6EFL6
uniprot id: A0A4W6EGQ1
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8187:tasp1
gene id: 8187:tasp1
uniprot id: A0A4W6BW43
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8187:clrn1
gene id: 8187:clrn1
uniprot id: A0A4W6BVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

8187:sardh
gene id: 8187:sardh
uniprot id: A0A4W6C8M0
names: Similarity
messages: Belongs to the GcvT family.

8187:popdc2
gene id: 8187:popdc2
uniprot id: A0A4W6EZB6
names: Similarity
messages: Belongs to the popeye family.

8187:wdfy2
gene id: 8187:wdfy2
uniprot id: A0A4W6EK45
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8187:gcnt7
gene id: 8187:gcnt7
uniprot id: A0A4W6EAS9
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8187:LOC108889066
gene id: 8187:LOC108889066
uniprot id: A0A4W6CWW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

8187:arf1
gene id: 8187:arf1
uniprot id: A0A4W6CFD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8187:chrna10a
gene id: 8187:chrna10a
uniprot id: A0A4W6DTF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:adam8a
gene id: 8187:adam8a
uniprot id: A0A4W6DSQ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:rpl38
gene id: 8187:rpl38
uniprot id: A0A4W6E048
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

8187:eya1
gene id: 8187:eya1
uniprot id: A0A4W6E2C6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

8187:tatdn3
gene id: 8187:tatdn3
uniprot id: A0A4W6F9I8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8187:LOC108883656
gene id: 8187:LOC108883656
uniprot id: A0A4W6F4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Part of the 60S ribosomal subunit.

8187:ezh2
gene id: 8187:ezh2
uniprot id: A0A4W6FT64
names: Subcellular Location Annotation
messages: Nucleus

8187:LOC108890255
gene id: 8187:LOC108890255
uniprot id: A0A4W6CRF8
names: Subcellular Location Annotation
messages: extracellular space

8187:LOC108886710
gene id: 8187:LOC108886710
uniprot id: A0A4W6FHN3
names: Similarity
messages: Belongs to the DeSI family.

8187:elovl8b
gene id: 8187:elovl8b
uniprot id: A0A4W6EWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

8187:admb
gene id: 8187:admb
uniprot id: A0A4W6FZJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

8187:LOC108889280
gene id: 8187:LOC108889280
uniprot id: A0A4W6F2C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

8187:timm22
gene id: 8187:timm22
uniprot id: A0A4W6ETS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

8187:axin2
gene id: 8187:axin2
uniprot id: A0A4W6DQE6
names: Subcellular Location Annotation
messages: Cytoplasm

8187:LOC108901349
gene id: 8187:LOC108901349
uniprot id: A0A4W6D1Q7
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

8187:tom1l2
gene id: 8187:tom1l2
uniprot id: A0A4W6GAA0
uniprot id: A0A4W6GBU0
names: Similarity
messages: Belongs to the TOM1 family.

8187:LOC108881284
gene id: 8187:LOC108881284
uniprot id: A0A4W6FBE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

8187:LOC108883643
gene id: 8187:LOC108883643
uniprot id: A0A4W6F3W6
names: Similarity
messages: Belongs to the DSH family.

8187:serpine3
gene id: 8187:serpine3
uniprot id: A0A4W6EHP1
names: Similarity
messages: Belongs to the serpin family.

8187:LOC108873991
gene id: 8187:LOC108873991
uniprot id: A0A4W6CIG4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

8187:LOC108883826
gene id: 8187:LOC108883826
uniprot id: A0A4W6BU86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

8187:LOC108880291
gene id: 8187:LOC108880291
uniprot id: A0A4W6C3E9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

8187:LOC108890733
gene id: 8187:LOC108890733
uniprot id: A0A4W6CG38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8187:zgc:158803
gene id: 8187:zgc:158803
uniprot id: A0A4W6FW54
uniprot id: A0A4W6FWV3
names: Similarity
messages: Belongs to the Luc7 family.

8187:bnip1b
gene id: 8187:bnip1b
uniprot id: A0A4W6F653
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108881903
gene id: 8187:LOC108881903
uniprot id: A0A4W6F0G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8187:nlgn3a
gene id: 8187:nlgn3a
uniprot id: A0A4W6DUP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8187:mych
gene id: 8187:mych
uniprot id: A0A4W6FH61
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

8187:LOC108879471
gene id: 8187:LOC108879471
uniprot id: A0A4W6DR00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8187:pard6b
gene id: 8187:pard6b
uniprot id: A0A4W6G296
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

8187:supt16h
gene id: 8187:supt16h
uniprot id: A0A4W6CGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

8187:mgat1a
gene id: 8187:mgat1a
uniprot id: A0A4W6BYD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

8187:farsb
gene id: 8187:farsb
uniprot id: A0A4W6C7E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

8187:alg5
gene id: 8187:alg5
uniprot id: A0A4W6FQF7
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

8187:gucy2d
gene id: 8187:gucy2d
uniprot id: A0A4W6BRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8187:apmap
gene id: 8187:apmap
uniprot id: A0A4W6F226
names: Similarity
messages: Belongs to the strictosidine synthase family.

8187:LOC108886947
gene id: 8187:LOC108886947
uniprot id: A0A4W6FM73
names: Subcellular Location Annotation
messages: Membrane

8187:irgq2
gene id: 8187:irgq2
uniprot id: A0A4W6BSN6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8187:LOC108896748
gene id: 8187:LOC108896748
uniprot id: A0A4W6D223
names: Similarity
messages: Belongs to the FAM110 family.

8187:mcm3
gene id: 8187:mcm3
uniprot id: A0A4W6CJI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

8187:inpp5kb
gene id: 8187:inpp5kb
uniprot id: A0A4W6DB30
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

8187:marco
gene id: 8187:marco
uniprot id: A0A4W6E0N9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:igfbp5a
gene id: 8187:igfbp5a
uniprot id: A0A4W6F3Y4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8187:phpt1
gene id: 8187:phpt1
uniprot id: A0A4W6FFF0
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

8187:stard3nl
gene id: 8187:stard3nl
uniprot id: A0A4W6BN14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Membrane

8187:cnot3a
gene id: 8187:cnot3a
uniprot id: A0A4W6FGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

8187:scarb1
gene id: 8187:scarb1
uniprot id: A0A4W6F1D3
uniprot id: A0A4W6F304
names: Similarity
messages: Belongs to the CD36 family.

8187:atp11a
gene id: 8187:atp11a
uniprot id: A0A4W6ELX3
uniprot id: A0A4W6EPD8
uniprot id: A0A4W6EQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8187:gabpa
gene id: 8187:gabpa
uniprot id: A0A4W6FEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8187:nipsnap1
gene id: 8187:nipsnap1
uniprot id: A0A4W6ECT5
names: Similarity
messages: Belongs to the NipSnap family.

8187:mms22l
gene id: 8187:mms22l
uniprot id: A0A4W6E1Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

8187:decr2
gene id: 8187:decr2
uniprot id: A0A4W6G0T0
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
messages: Monomer, dimer and oligomer.

8187:pgp
gene id: 8187:pgp
uniprot id: A0A4W6GAT0
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

8187:lsamp
gene id: 8187:lsamp
uniprot id: A0A4W6C337
names: Subcellular Location Annotation
messages: Membrane

8187:hspa4b
gene id: 8187:hspa4b
uniprot id: A0A4W6E3G9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8187:LOC108892527
gene id: 8187:LOC108892527
uniprot id: A0A4W6ETW3
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

8187:kcnj12b
gene id: 8187:kcnj12b
uniprot id: A0A4W6BRA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

8187:metap1d
gene id: 8187:metap1d
uniprot id: A0A4W6EV40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

8187:snx11
gene id: 8187:snx11
uniprot id: A0A4W6E1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8187:arhgef7b
gene id: 8187:arhgef7b
uniprot id: A0A4W6ESJ6
names: Subcellular Location Annotation
messages: lamellipodium

8187:adam12b
gene id: 8187:adam12b
uniprot id: A0A4W6DJ10
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:smtla
gene id: 8187:smtla
uniprot id: A0A4W6CW89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

8187:zgc:101540
gene id: 8187:zgc:101540
uniprot id: A0A4W6CZL7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8187:sult2st3
gene id: 8187:sult2st3
uniprot id: A0A4W6EAV6
uniprot id: A0A4W6EF25
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:LOC108890585
gene id: 8187:LOC108890585
uniprot id: A0A4W6FJV2
uniprot id: A0A4W6FLU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8187:LOC108892519
gene id: 8187:LOC108892519
uniprot id: A0A4W6DGL6
names: Similarity
messages: Belongs to the phospholipase D family.

8187:tle5
gene id: 8187:tle5
uniprot id: A0A4W6G5A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8187:olfml2a
gene id: 8187:olfml2a
uniprot id: A0A4W6G4V6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108888953
gene id: 8187:LOC108888953
uniprot id: A0A4W6CLY2
names: Subcellular Location Annotation
messages: Membrane

8187:rhcga
gene id: 8187:rhcga
uniprot id: A0A4W6C767
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8187:gnb3a
gene id: 8187:gnb3a
uniprot id: A0A4W6CEC2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8187:gtf2a1
gene id: 8187:gtf2a1
uniprot id: A0A4W6CAL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

8187:LOC108900389
gene id: 8187:LOC108900389
uniprot id: A0A4W6FRB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8187:bcl2l1
gene id: 8187:bcl2l1
uniprot id: A0A4W6BQD5
names: Similarity
messages: Belongs to the Bcl-2 family.

8187:rhbdl3
gene id: 8187:rhbdl3
uniprot id: A0A4W6FSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

8187:pvalb8
gene id: 8187:pvalb8
uniprot id: A0A4W6DX16
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8187:mrasa
gene id: 8187:mrasa
uniprot id: A0A4W6GA89
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8187:LOC108884661
gene id: 8187:LOC108884661
uniprot id: A0A4W6FYY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:si:ch211-145o7.3
gene id: 8187:si:ch211-145o7.3
uniprot id: A0A4W6EXU1
names: Subcellular Location Annotation
messages: Nucleus

8187:msrb2
gene id: 8187:msrb2
uniprot id: A0A4W6FP19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

8187:kcnj2a
gene id: 8187:kcnj2a
uniprot id: A0A4W6FVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

8187:sts
gene id: 8187:sts
uniprot id: A0A4W6EE22
names: Similarity
messages: Belongs to the sulfatase family.

8187:nr0b2a
gene id: 8187:nr0b2a
uniprot id: A0A4W6CJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8187:adgrb3
gene id: 8187:adgrb3
uniprot id: A0A4W6EHS4
names: Subcellular Location Annotation
messages: Membrane

8187:slc17a6b
gene id: 8187:slc17a6b
uniprot id: A0A4W6F0R1
names: Subcellular Location Annotation
messages: Membrane

8187:grm3
gene id: 8187:grm3
uniprot id: A0A4W6DEJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

8187:LOC108897679
gene id: 8187:LOC108897679
uniprot id: A0A4W6G7E0
names: Subcellular Location Annotation
messages: Nucleus

8187:cdk5
gene id: 8187:cdk5
uniprot id: A0A4W6CFK2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8187:LOC108878691
gene id: 8187:LOC108878691
uniprot id: A0A4W6BLQ8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8187:ccnyl1
gene id: 8187:ccnyl1
uniprot id: A0A4W6DJ92
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8187:kif4
gene id: 8187:kif4
uniprot id: A0A4W6F2E3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8187:LOC108902462
gene id: 8187:LOC108902462
uniprot id: A0A4W6F4C9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8187:si:dkey-106n21.1
gene id: 8187:si:dkey-106n21.1
uniprot id: A0A4W6C1K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8187:LOC108901962
gene id: 8187:LOC108901962
uniprot id: A0A4W6D0M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium axoneme
messages: kinetochore
messages: spindle

8187:si:dkey-148a17.6
gene id: 8187:si:dkey-148a17.6
uniprot id: A0A4W6FUD4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8187:abcb10
gene id: 8187:abcb10
uniprot id: A0A4W6G0Z1
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108883586
gene id: 8187:LOC108883586
uniprot id: A0A4W6EBW5
names: Similarity
messages: Belongs to the SPIN/STSY family.

8187:LOC108875876
gene id: 8187:LOC108875876
uniprot id: A0A4W6FY91
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8187:tubgcp4
gene id: 8187:tubgcp4
uniprot id: A0A4W6C8M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

8187:grpr
gene id: 8187:grpr
uniprot id: A0A4W6CK03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8187:LOC108893349
gene id: 8187:LOC108893349
uniprot id: A0A4W6CBK0
names: Similarity
messages: Belongs to the spectrin family.

8187:rspo2
gene id: 8187:rspo2
uniprot id: A0A4W6EAW2
names: Similarity
messages: Belongs to the R-spondin family.

8187:msrab
gene id: 8187:msrab
uniprot id: A0A4W6EQE0
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

8187:LOC108880419
gene id: 8187:LOC108880419
uniprot id: A0A4W6EZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8187:puf60a
gene id: 8187:puf60a
uniprot id: A0A4W6CL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

8187:hdc
gene id: 8187:hdc
uniprot id: A0A4W6CER3
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8187:tmem8b
gene id: 8187:tmem8b
uniprot id: A0A4W6EWF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

8187:rngtt
gene id: 8187:rngtt
uniprot id: A0A4W6EJC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

8187:sec24d
gene id: 8187:sec24d
uniprot id: A0A4W6EBR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8187:LOC108894930
gene id: 8187:LOC108894930
uniprot id: A0A4W6BWU4
uniprot id: A0A4W6C4C3
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

8187:paqr3a
gene id: 8187:paqr3a
uniprot id: A0A4W6CNT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8187:LOC108876274
gene id: 8187:LOC108876274
uniprot id: A0A4W6F059
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8187:LOC108894289
gene id: 8187:LOC108894289
uniprot id: A0A4W6CC37
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

8187:hpxb
gene id: 8187:hpxb
uniprot id: A0A4W6C1K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

8187:LOC108901470
gene id: 8187:LOC108901470
uniprot id: A0A4W6BN97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

8187:metap1
gene id: 8187:metap1
uniprot id: A0A4W6F9K4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

8187:LOC108873726
gene id: 8187:LOC108873726
uniprot id: A0A4W6FD88
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8187:hmgcl
gene id: 8187:hmgcl
uniprot id: A0A4W6DRA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

8187:pou3f1
gene id: 8187:pou3f1
uniprot id: A0A4W6C7F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8187:LOC108884216
gene id: 8187:LOC108884216
uniprot id: A0A4W6F702
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8187:LOC108899847
gene id: 8187:LOC108899847
uniprot id: A0A4W6E128
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:mfsd3
gene id: 8187:mfsd3
uniprot id: A0A4W6FX50
names: Subcellular Location Annotation
messages: Membrane

8187:anxa14
gene id: 8187:anxa14
uniprot id: A0A4W6EUX3
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8187:paqr6
gene id: 8187:paqr6
uniprot id: A0A4W6BMU4
uniprot id: A0A4W6BV94
uniprot id: A0A4W6BV99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8187:efna5b
gene id: 8187:efna5b
uniprot id: A0A4W6CIN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:ptpn6
gene id: 8187:ptpn6
uniprot id: A0A4W6CTY2
uniprot id: A0A4W6CUG7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.

8187:top2a
gene id: 8187:top2a
uniprot id: A0A4W6DEG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

8187:ca4a
gene id: 8187:ca4a
uniprot id: A0A4W6ES14
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8187:usp5
gene id: 8187:usp5
uniprot id: A0A4W6CDN1
names: Similarity
messages: Belongs to the peptidase C19 family.

8187:usp10
gene id: 8187:usp10
uniprot id: A0A4W6EF36
uniprot id: A0A4W6EF41
names: Similarity
messages: Belongs to the peptidase C19 family.

8187:kras
gene id: 8187:kras
uniprot id: A0A4W6ECC5
uniprot id: A0A4W6ECD5
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8187:hamp
gene id: 8187:hamp
uniprot id: G3FZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8187:hmox2b
gene id: 8187:hmox2b
uniprot id: A0A4W6BPF2
names: Similarity
messages: Belongs to the heme oxygenase family.

8187:tmem218
gene id: 8187:tmem218
uniprot id: A0A4W6DVP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

8187:LOC108899011
gene id: 8187:LOC108899011
uniprot id: A0A4W6DS89
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8187:usp49
gene id: 8187:usp49
uniprot id: A0A4W6EI98
names: Similarity
messages: Belongs to the peptidase C19 family.

8187:LOC108894047
gene id: 8187:LOC108894047
uniprot id: A0A4W6FWZ4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

8187:LOC108886734
gene id: 8187:LOC108886734
uniprot id: A0A4W6FQA4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8187:LOC108896269
gene id: 8187:LOC108896269
uniprot id: A0A4W6EYF5
names: Subcellular Location Annotation
messages: Membrane

8187:zdhhc6
gene id: 8187:zdhhc6
uniprot id: A0A4W6BTT1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8187:gpr158a
gene id: 8187:gpr158a
uniprot id: A0A4W6DUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8187:gprin3b
gene id: 8187:gprin3b
uniprot id: A0A4W6BQT1
names: Function
messages: May be involved in neurite outgrowth.

8187:LOC108890629
gene id: 8187:LOC108890629
uniprot id: A0A4W6G1K8
names: Similarity
messages: Belongs to the cytochrome b5 family.

8187:tbxta
gene id: 8187:tbxta
uniprot id: A0A4W6CHY8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8187:rps13
gene id: 8187:rps13
uniprot id: A0A4W6FX64
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

8187:ppp2r5ca
gene id: 8187:ppp2r5ca
uniprot id: A0A4W6F3V4
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8187:ccdc126
gene id: 8187:ccdc126
uniprot id: A0A4W6ECH6
names: Subcellular Location Annotation
messages: Secreted

8187:LOC108880019
gene id: 8187:LOC108880019
uniprot id: Q6ITU9
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8187:rbp5
gene id: 8187:rbp5
uniprot id: A0A4W6CU64
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8187:LOC108900851
gene id: 8187:LOC108900851
uniprot id: A0A4W6CSC8
names: Similarity
messages: Belongs to the SH2B adapter family.

8187:LOC108875625
gene id: 8187:LOC108875625
uniprot id: A0A4W6D854
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8187:pex5
gene id: 8187:pex5
uniprot id: A0A4W6CEG7
uniprot id: A0A4W6CEH2
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

8187:bmp10
gene id: 8187:bmp10
uniprot id: A0A4W6E5V4
names: Similarity
messages: Belongs to the TGF-beta family.

8187:lhfpl2a
gene id: 8187:lhfpl2a
uniprot id: A0A4W6CYY6
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108879782
gene id: 8187:LOC108879782
uniprot id: A0A4W6DTN7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8187:nkx3-2
gene id: 8187:nkx3-2
uniprot id: A0A4W6FLZ3
names: Subcellular Location Annotation
messages: Nucleus

8187:cldn15a
gene id: 8187:cldn15a
uniprot id: A0A4W6CNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8187:spaw
gene id: 8187:spaw
uniprot id: A0A4W6GBB0
names: Similarity
messages: Belongs to the TGF-beta family.

8187:foxk2a
gene id: 8187:foxk2a
uniprot id: A0A4W6EX34
names: Subcellular Location Annotation
messages: Nucleus

8187:ndufa1
gene id: 8187:ndufa1
uniprot id: A0A4W6FSW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

8187:LOC108886934
gene id: 8187:LOC108886934
uniprot id: A0A4W6FKV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

8187:kdelr2b
gene id: 8187:kdelr2b
uniprot id: A0A4W6EWJ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:abcd4
gene id: 8187:abcd4
uniprot id: A0A4W6D0A3
names: Subcellular Location Annotation
messages: Membrane

8187:LOC108884123
gene id: 8187:LOC108884123
uniprot id: A0A4W6C4R1
names: Subcellular Location Annotation
messages: Membrane

8187:st6galnac5a
gene id: 8187:st6galnac5a
uniprot id: A0A4W6FUP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8187:psenen
gene id: 8187:psenen
uniprot id: A0A4W6CYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

8187:grhprb
gene id: 8187:grhprb
uniprot id: A0A4W6BMK5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8187:rabggtb
gene id: 8187:rabggtb
uniprot id: A0A4W6FUW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

8187:alpl
gene id: 8187:alpl
uniprot id: A0A4W6DJ59
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

8187:LOC108892574
gene id: 8187:LOC108892574
uniprot id: A0A4W6EUL0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8187:LOC108896320
gene id: 8187:LOC108896320
uniprot id: A0A4W6DFB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8187:LOC108872855
gene id: 8187:LOC108872855
uniprot id: A0A4W6BRZ6
names: Similarity
messages: Belongs to the cytochrome P450 family.

8187:LOC108902607
gene id: 8187:LOC108902607
uniprot id: A0A4W6C380
uniprot id: A0A4W6CAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

8187:zgc:172282
gene id: 8187:zgc:172282
uniprot id: A0A4W6D2H5
names: Subcellular Location Annotation
messages: Membrane

8187:xpnpep2
gene id: 8187:xpnpep2
uniprot id: A0A4W6FUT1
names: Similarity
messages: Belongs to the peptidase M24B family.

8187:LOC108893687
gene id: 8187:LOC108893687
uniprot id: A0A4W6CNX9
names: Similarity
messages: Belongs to the GDNFR family.

8187:ccdc93
gene id: 8187:ccdc93
uniprot id: A0A4W6E1K8
names: Similarity
messages: Belongs to the CCDC93 family.

8187:tpi1b
gene id: 8187:tpi1b
uniprot id: A0A4W6CGV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8187:pex13
gene id: 8187:pex13
uniprot id: A0A4W6BYG0
names: Similarity
messages: Belongs to the peroxin-13 family.

8187:panx2
gene id: 8187:panx2
uniprot id: A0A4W6EWW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8187:rpl35
gene id: 8187:rpl35
uniprot id: A0A4W6G4J9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

8187:spsb3a
gene id: 8187:spsb3a
uniprot id: A0A4W6BLL3
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

8187:LOC108888074
gene id: 8187:LOC108888074
uniprot id: A0A4W6D5R6
names: Subcellular Location Annotation
messages: Membrane

8187:pik3cb
gene id: 8187:pik3cb
uniprot id: A0A4W6C836
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8187:ube3d
gene id: 8187:ube3d
uniprot id: A0A4W6E4H7
uniprot id: A0A4W6E6N9
uniprot id: A0A4W6E731
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

8187:hspb9
gene id: 8187:hspb9
uniprot id: A0A4W6DVU9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8187:gprc5ba
gene id: 8187:gprc5ba
uniprot id: A0A4W6BZS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8187:ykt6
gene id: 8187:ykt6
uniprot id: A0A4W6BMR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

8187:flvcr1
gene id: 8187:flvcr1
uniprot id: A0A4W6F8L0
names: Subcellular Location Annotation
messages: Membrane

8187:efna1a
gene id: 8187:efna1a
uniprot id: A0A4W6FC10
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8187:cdc42
gene id: 8187:cdc42
uniprot id: A0A4W6FG31
uniprot id: A0A4W6FIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8187:LOC108896504
gene id: 8187:LOC108896504
uniprot id: A0A4W6C1S3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

8187:LOC108892256
gene id: 8187:LOC108892256
uniprot id: A0A4W6DI80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

8187:pmepa1
gene id: 8187:pmepa1
uniprot id: A0A4W6ESE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8187:esrrgb
gene id: 8187:esrrgb
uniprot id: A0A4W6CYJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8187:cenph
gene id: 8187:cenph
uniprot id: A0A4W6GBX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

8187:jak2a
gene id: 8187:jak2a
uniprot id: A0A4W6C5M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

8187:pemt
gene id: 8187:pemt
uniprot id: A0A4W6EC08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

8187:LOC108890619
gene id: 8187:LOC108890619
uniprot id: A0A4W6CXG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8187:tiparp
gene id: 8187:tiparp
uniprot id: A0A4W6CNY7
names: Similarity
messages: Belongs to the ARTD/PARP family.

8187:kitlga
gene id: 8187:kitlga
uniprot id: A0A4W6BW99
uniprot id: A0A4W6C3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

8187:ddx59
gene id: 8187:ddx59
uniprot id: A0A4W6D724
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

8187:LOC108882288
gene id: 8187:LOC108882288
uniprot id: A0A4W6DSC4
names: Similarity
messages: Belongs to the peptidase C2 family.

8187:eif2b5
gene id: 8187:eif2b5
uniprot id: A0A4W6CFM4
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

8187:LOC108897571
gene id: 8187:LOC108897571
uniprot id: A0A4W6G4M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8187:tafa3a
gene id: 8187:tafa3a
uniprot id: A0A4W6EH49
names: Similarity
messages: Belongs to the TAFA family.

8187:insrb
gene id: 8187:insrb
uniprot id: A0A4W6FP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

8187:trim3b
gene id: 8187:trim3b
uniprot id: A0A4W6FU50
names: Similarity
messages: Belongs to the TRIM/RBCC family.