8128:gpt
gene id: 8128:gpt
uniprot id: I3KAH6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8128:timm8a
gene id: 8128:timm8a
uniprot id: A0A669BNP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8128:LOC100701914
gene id: 8128:LOC100701914
uniprot id: I3JGF5
names: Similarity
messages: Belongs to the MAGUK family.

8128:LOC100534530
gene id: 8128:LOC100534530
uniprot id: I3KPG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8128:LOC100692108
gene id: 8128:LOC100692108
uniprot id: I3KGC0
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

8128:shkbp1
gene id: 8128:shkbp1
uniprot id: A0A669ETT3
uniprot id: I3IXT2
names: Similarity
messages: Belongs to the KCTD3 family.

8128:LOC100702093
gene id: 8128:LOC100702093
uniprot id: I3JYU7
names: Subcellular Location Annotation
messages: Membrane

8128:foxn3
gene id: 8128:foxn3
uniprot id: I3IXX6
names: Function
names: Subcellular Location Annotation
messages: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).
messages: Nucleus

8128:LOC100711602
gene id: 8128:LOC100711602
uniprot id: I3K4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

8128:esr1
gene id: 8128:esr1
uniprot id: Q9YH33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer. Can form a heterodimer with ER-beta (By similarity).
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

8128:guk1
gene id: 8128:guk1
uniprot id: A0A669B9P2
uniprot id: I3JSS7
names: Similarity
messages: Belongs to the guanylate kinase family.

8128:rad18
gene id: 8128:rad18
uniprot id: A0A669ELQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

8128:LOC100707652
gene id: 8128:LOC100707652
uniprot id: A0A669D1B5
uniprot id: A0A669F028
names: Subcellular Location Annotation
messages: Membrane

8128:gle1
gene id: 8128:gle1
uniprot id: A0A669DSA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

8128:amigo3
gene id: 8128:amigo3
uniprot id: I3KY24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

8128:ache
gene id: 8128:ache
uniprot id: A0A669DKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

8128:elovl6
gene id: 8128:elovl6
uniprot id: I3IXR5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

8128:lpin1
gene id: 8128:lpin1
uniprot id: I3IVR4
names: Similarity
messages: Belongs to the lipin family.

8128:LOC100706322
gene id: 8128:LOC100706322
uniprot id: A0A669BEW1
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8128:ctu1
gene id: 8128:ctu1
uniprot id: I3JYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

8128:myd88
gene id: 8128:myd88
uniprot id: X2KPT4
names: Function
names: Subcellular Location Annotation
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm

8128:LOC109201860
gene id: 8128:LOC109201860
uniprot id: A0A669DUA0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:rpl30
gene id: 8128:rpl30
uniprot id: I3J3A6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

8128:glb1
gene id: 8128:glb1
uniprot id: A0A669BGM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

8128:LOC102076014
gene id: 8128:LOC102076014
uniprot id: A0A669BNS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:pqlc2l
gene id: 8128:pqlc2l
uniprot id: I3JDN2
names: Subcellular Location Annotation
messages: Membrane

8128:banf1
gene id: 8128:banf1
uniprot id: A0A669CS07
names: Subcellular Location Annotation
messages: Nucleus

8128:tmeff1
gene id: 8128:tmeff1
uniprot id: A0A669CXF0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100708395
gene id: 8128:LOC100708395
uniprot id: A0A669D716
uniprot id: A0A669E8V6
uniprot id: A0A669EE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8128:LOC102081683
gene id: 8128:LOC102081683
uniprot id: A0A669DJX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ppp3r1
gene id: 8128:ppp3r1
uniprot id: A0A669B2I9
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

8128:nob1
gene id: 8128:nob1
uniprot id: A0A669BG61
uniprot id: I3J5N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

8128:lrwd1
gene id: 8128:lrwd1
uniprot id: I3JSP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

8128:LOC109194535
gene id: 8128:LOC109194535
uniprot id: A0A669CYS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

8128:serpine2
gene id: 8128:serpine2
uniprot id: A0A669EQF9
uniprot id: I3JXD9
names: Similarity
messages: Belongs to the serpin family.

8128:LOC102079960
gene id: 8128:LOC102079960
uniprot id: I3J7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8128:LOC102076923
gene id: 8128:LOC102076923
uniprot id: A0A669EQE7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:cplx4
gene id: 8128:cplx4
uniprot id: I3JLE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8128:LOC100693397
gene id: 8128:LOC100693397
uniprot id: A0A669D6B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion

8128:LOC100708648
gene id: 8128:LOC100708648
uniprot id: I3KFS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:cfap45
gene id: 8128:cfap45
uniprot id: I3JD81
names: Similarity
messages: Belongs to the CFAP45 family.

8128:LOC100696639
gene id: 8128:LOC100696639
uniprot id: A0A669EVX4
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100695037
gene id: 8128:LOC100695037
uniprot id: A0A669E5N1
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:ahcyl2
gene id: 8128:ahcyl2
uniprot id: I3KIY4
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

8128:eif5
gene id: 8128:eif5
uniprot id: I3K3D4
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

8128:fabp2
gene id: 8128:fabp2
uniprot id: I3KM58
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:LOC102081410
gene id: 8128:LOC102081410
uniprot id: A0A669AYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8128:trit1
gene id: 8128:trit1
uniprot id: I3KE38
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

8128:terf1
gene id: 8128:terf1
uniprot id: I3KA17
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus

8128:LOC100695498
gene id: 8128:LOC100695498
uniprot id: A0A669F8R8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:lg16h2orf40
gene id: 8128:lg16h2orf40
uniprot id: I3K9S7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

8128:LOC100702465
gene id: 8128:LOC100702465
uniprot id: A0A669EDY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

8128:megf11
gene id: 8128:megf11
uniprot id: A0A669CFB9
uniprot id: A0A669DPS1
uniprot id: A0A669DYT1
uniprot id: A0A669EHZ7
uniprot id: I3KE67
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100708001
gene id: 8128:LOC100708001
uniprot id: I3IYD2
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:sptssa
gene id: 8128:sptssa
uniprot id: A0A669E956
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100695903
gene id: 8128:LOC100695903
uniprot id: I3IY91
names: Similarity
messages: Belongs to the TGF-beta family.

8128:esrra
gene id: 8128:esrra
uniprot id: I3J035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8128:LOC100698318
gene id: 8128:LOC100698318
uniprot id: A0A669EQD2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC109195630
gene id: 8128:LOC109195630
uniprot id: I3KZ77
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:ezr
gene id: 8128:ezr
uniprot id: A0A669AYU2
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8128:LOC100699231
gene id: 8128:LOC100699231
uniprot id: A0A669CX62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:LOC100692215
gene id: 8128:LOC100692215
uniprot id: A0A669BF99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

8128:LOC100707632
gene id: 8128:LOC100707632
uniprot id: I3K1M0
names: Similarity
messages: Belongs to the SAPS family.

8128:LOC100693653
gene id: 8128:LOC100693653
uniprot id: A0A669BCP7
names: Similarity
messages: Belongs to the FHIP family.

8128:LOC100698945
gene id: 8128:LOC100698945
uniprot id: I3KNR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

8128:LOC100704291
gene id: 8128:LOC100704291
uniprot id: A0A669DRJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8128:LOC106097937
gene id: 8128:LOC106097937
uniprot id: A0A669CVU9
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

8128:LOC100710934
gene id: 8128:LOC100710934
uniprot id: A0A669B1N5
uniprot id: A0A669B1T2
uniprot id: A0A669E6E3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:LOC100698911
gene id: 8128:LOC100698911
uniprot id: I3IV39
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

8128:ddx56
gene id: 8128:ddx56
uniprot id: A0A669BGD4
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8128:casp7
gene id: 8128:casp7
uniprot id: A0A669EKX7
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:rhbdl2
gene id: 8128:rhbdl2
uniprot id: I3KHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

8128:LOC100698939
gene id: 8128:LOC100698939
uniprot id: I3K347
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:ano3
gene id: 8128:ano3
uniprot id: I3JNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

8128:agt
gene id: 8128:agt
uniprot id: I3IVP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serpin family.
messages: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis.
messages: Secreted
messages: Stimulates aldosterone release.

8128:LOC100701948
gene id: 8128:LOC100701948
uniprot id: I3JJ89
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

8128:flt4
gene id: 8128:flt4
uniprot id: I3KMT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:b4galnt4
gene id: 8128:b4galnt4
uniprot id: A0A669BGD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

8128:LOC100698564
gene id: 8128:LOC100698564
uniprot id: A0A669DBS8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8128:LOC106096764
gene id: 8128:LOC106096764
uniprot id: A0A669DM61
names: Similarity
messages: Belongs to the HARBI1 family.

8128:LOC100705626
gene id: 8128:LOC100705626
uniprot id: I3IW93
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

8128:LOC100693384
gene id: 8128:LOC100693384
uniprot id: I3JI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum
messages: flagellum axoneme

8128:usp9x
gene id: 8128:usp9x
uniprot id: A0A669C712
uniprot id: A0A669EWD1
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:LOC100697500
gene id: 8128:LOC100697500
uniprot id: I3IX00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:ndufb5
gene id: 8128:ndufb5
uniprot id: I3IZS3
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

8128:LOC100707010
gene id: 8128:LOC100707010
uniprot id: I3K0A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8128:gtf2h1
gene id: 8128:gtf2h1
uniprot id: A0A669B4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

8128:LOC100712516
gene id: 8128:LOC100712516
uniprot id: A0A669C705
uniprot id: I3KU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100693550
gene id: 8128:LOC100693550
uniprot id: I3JIM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

8128:LOC100692431
gene id: 8128:LOC100692431
uniprot id: A0A669EES9
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

8128:igsf8
gene id: 8128:igsf8
uniprot id: I3JC35
names: Subcellular Location Annotation
messages: Membrane

8128:taf8
gene id: 8128:taf8
uniprot id: I3KI87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

8128:LOC100698356
gene id: 8128:LOC100698356
uniprot id: I3KMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100695123
gene id: 8128:LOC100695123
uniprot id: I3JUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

8128:LOC100692305
gene id: 8128:LOC100692305
uniprot id: I3J5T5
names: Similarity
messages: Belongs to the stathmin family.

8128:cdca8
gene id: 8128:cdca8
uniprot id: I3K7K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

8128:pih1d2
gene id: 8128:pih1d2
uniprot id: I3JYM6
names: Similarity
messages: Belongs to the PIH1 family.

8128:ncln
gene id: 8128:ncln
uniprot id: A0A669BUX4
names: Similarity
messages: Belongs to the nicastrin family.

8128:LOC100695783
gene id: 8128:LOC100695783
uniprot id: A0A669EQ59
names: Similarity
messages: Belongs to the NLRP family.

8128:LOC100698401
gene id: 8128:LOC100698401
uniprot id: A0A669CI95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:xkr9
gene id: 8128:xkr9
uniprot id: I3K9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:LOC100696880
gene id: 8128:LOC100696880
uniprot id: I3JCB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:ano5
gene id: 8128:ano5
uniprot id: I3JNH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:tmem145
gene id: 8128:tmem145
uniprot id: A0A669E3Y0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100706122
gene id: 8128:LOC100706122
uniprot id: I3JBB3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100700221
gene id: 8128:LOC100700221
uniprot id: A0A669E9D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:LOC100704335
gene id: 8128:LOC100704335
uniprot id: I3JPJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:foxp2
gene id: 8128:foxp2
uniprot id: V6F808
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100703874
gene id: 8128:LOC100703874
uniprot id: A0A669CL15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

8128:prpf38b
gene id: 8128:prpf38b
uniprot id: A0A669CS11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

8128:LOC100705693
gene id: 8128:LOC100705693
uniprot id: I3JHU7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100710823
gene id: 8128:LOC100710823
uniprot id: I3K7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:psap
gene id: 8128:psap
uniprot id: I3JUC5
names: Function
names: Subcellular Location Annotation
messages: Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
messages: Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
messages: Secreted

8128:cldn14
gene id: 8128:cldn14
uniprot id: A0A669DA69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100693866
gene id: 8128:LOC100693866
uniprot id: I3KSN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8128:lg10h11orf54
gene id: 8128:lg10h11orf54
uniprot id: A0A669CAQ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

8128:id1
gene id: 8128:id1
uniprot id: A0A669E9M2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100691066
gene id: 8128:LOC100691066
uniprot id: A0A669D7T7
uniprot id: A0A669FC26
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8128:LOC100705132
gene id: 8128:LOC100705132
uniprot id: I3KH58
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100694789
gene id: 8128:LOC100694789
uniprot id: A0A669BJS5
uniprot id: A0A669EZA5
uniprot id: I3JKJ5
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8128:tbk1
gene id: 8128:tbk1
uniprot id: A0A669BN94
names: Subcellular Location Annotation
messages: Cytoplasm

8128:prdm8
gene id: 8128:prdm8
uniprot id: I3K952
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100712491
gene id: 8128:LOC100712491
uniprot id: I3J4R0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:vta1
gene id: 8128:vta1
uniprot id: A0A669D7N7
uniprot id: A0A669EX18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

8128:icmt
gene id: 8128:icmt
uniprot id: I3KNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC102077603
gene id: 8128:LOC102077603
uniprot id: A0A669EY31
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704763
gene id: 8128:LOC100704763
uniprot id: I3KZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:mrps12
gene id: 8128:mrps12
uniprot id: I3J0Z0
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

8128:LOC102082670
gene id: 8128:LOC102082670
uniprot id: A0A669CBC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100691565
gene id: 8128:LOC100691565
uniprot id: A0A669DMD8
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8128:LOC100706281
gene id: 8128:LOC100706281
uniprot id: I3KKN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:kif6
gene id: 8128:kif6
uniprot id: I3KU29
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:fmr1
gene id: 8128:fmr1
uniprot id: A0A669EGF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Stress granule
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

8128:LOC100706519
gene id: 8128:LOC100706519
uniprot id: A0A669BIZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:prkaca
gene id: 8128:prkaca
uniprot id: I3KHS3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

8128:plcd1
gene id: 8128:plcd1
uniprot id: A0A669BFI1
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

8128:LOC100691101
gene id: 8128:LOC100691101
uniprot id: I3K335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100710960
gene id: 8128:LOC100710960
uniprot id: A0A669EE97
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8128:LOC102083126
gene id: 8128:LOC102083126
uniprot id: I3IV50
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

8128:prune1
gene id: 8128:prune1
uniprot id: I3IZ22
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

8128:LOC100691407
gene id: 8128:LOC100691407
uniprot id: I3KDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100706341
gene id: 8128:LOC100706341
uniprot id: A0A669BEQ6
names: Similarity
messages: Belongs to the WD repeat EBI family.

8128:pnrc2
gene id: 8128:pnrc2
uniprot id: I3KZ69
names: Subcellular Location Annotation
messages: Nucleus

8128:ccnj
gene id: 8128:ccnj
uniprot id: I3KC38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:gtf2h4
gene id: 8128:gtf2h4
uniprot id: A0A669DR79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

8128:LOC100695259
gene id: 8128:LOC100695259
uniprot id: I3JWE5
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

8128:isca1
gene id: 8128:isca1
uniprot id: A0A669E4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

8128:LOC100706164
gene id: 8128:LOC100706164
uniprot id: I3KNV2
names: Similarity
messages: Belongs to the Bcl-2 family.

8128:LOC100694889
gene id: 8128:LOC100694889
uniprot id: I3K9U1
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

8128:LOC100707222
gene id: 8128:LOC100707222
uniprot id: I3KYE6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100534516
gene id: 8128:LOC100534516
uniprot id: Q6R671
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC102082344
gene id: 8128:LOC102082344
uniprot id: A0A669B0E2
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

8128:LOC100711993
gene id: 8128:LOC100711993
uniprot id: I3KD26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

8128:LOC100693808
gene id: 8128:LOC100693808
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:gata2
gene id: 8128:gata2
uniprot id: I3KS72
names: Subcellular Location Annotation
messages: Nucleus

8128:arpin
gene id: 8128:arpin
uniprot id: I3JXN0
names: Similarity
messages: Belongs to the Arpin family.

8128:LOC100695242
gene id: 8128:LOC100695242
uniprot id: I3KW52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:ndufs2
gene id: 8128:ndufs2
uniprot id: I3KPP7
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

8128:atg4b
gene id: 8128:atg4b
uniprot id: A0A669E9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8128:LOC100710139
gene id: 8128:LOC100710139
uniprot id: I3J2F8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100700025
gene id: 8128:LOC100700025
uniprot id: I3JH83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8128:LOC100693750
gene id: 8128:LOC100693750
uniprot id: A0A669BCE5
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:il17rb
gene id: 8128:il17rb
uniprot id: A0A669F6L0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100701817
gene id: 8128:LOC100701817
uniprot id: I3J6F2
names: Similarity
messages: Belongs to the PP2C family.

8128:tcp1
gene id: 8128:tcp1
uniprot id: I3K6A8
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

8128:eml1
gene id: 8128:eml1
uniprot id: A0A669D4J8
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8128:nup85
gene id: 8128:nup85
uniprot id: A0A669BL51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

8128:mocs3
gene id: 8128:mocs3
uniprot id: A0A669C1D5
uniprot id: I3JMZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

8128:clu
gene id: 8128:clu
uniprot id: I3JE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol

8128:LOC100712464
gene id: 8128:LOC100712464
uniprot id: I3JG73
names: Subcellular Location Annotation
messages: extracellular space

8128:cpped1
gene id: 8128:cpped1
uniprot id: I3KUS8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.

8128:LOC100698303
gene id: 8128:LOC100698303
uniprot id: I3JDJ1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100712575
gene id: 8128:LOC100712575
uniprot id: A0A669D7Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8128:snw1
gene id: 8128:snw1
uniprot id: I3IXQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

8128:psma8
gene id: 8128:psma8
uniprot id: A0A669BSJ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8128:LOC100712552
gene id: 8128:LOC100712552
uniprot id: A0A669BTX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

8128:prkcq
gene id: 8128:prkcq
uniprot id: I3KN71
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8128:runx3
gene id: 8128:runx3
uniprot id: A0A669B1Y1
names: Subcellular Location Annotation
messages: Nucleus

8128:mrpl15
gene id: 8128:mrpl15
uniprot id: I3JFT5
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

8128:LOC109204043
gene id: 8128:LOC109204043
uniprot id: I3ITW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8128:LOC100701346
gene id: 8128:LOC100701346
uniprot id: A0A669B2F3
names: Subcellular Location Annotation
messages: Mitochondrion

8128:ppard
gene id: 8128:ppard
uniprot id: I3K1E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:lhx4
gene id: 8128:lhx4
uniprot id: I3J0L0
names: Subcellular Location Annotation
messages: Nucleus

8128:mlf2
gene id: 8128:mlf2
uniprot id: A0A669BN71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

8128:mif
gene id: 8128:mif
uniprot id: A0A669CK57
names: Similarity
messages: Belongs to the MIF family.

8128:LOC100704006
gene id: 8128:LOC100704006
uniprot id: I3K730
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8128:coq8a
gene id: 8128:coq8a
uniprot id: A0A669BC24
uniprot id: A0A669CNF1
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8128:btf3
gene id: 8128:btf3
uniprot id: A0A669EXN1
names: Similarity
messages: Belongs to the NAC-beta family.

8128:zic3
gene id: 8128:zic3
uniprot id: I3J3G5
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8128:LOC100693120
gene id: 8128:LOC100693120
uniprot id: A0A669EYJ5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:furin
gene id: 8128:furin
uniprot id: I3KB78
names: Similarity
messages: Belongs to the peptidase S8 family.

8128:ergic1
gene id: 8128:ergic1
uniprot id: A0A669CVB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8128:LOC100697860
gene id: 8128:LOC100697860
uniprot id: I3KG45
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100705409
gene id: 8128:LOC100705409
uniprot id: A0A669CB22
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:foxf2
gene id: 8128:foxf2
uniprot id: I3JGT6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100702060
gene id: 8128:LOC100702060
uniprot id: A0A669C9T2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:cyyr1
gene id: 8128:cyyr1
uniprot id: I3K2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYYR1 family.
messages: Membrane

8128:LOC100692650
gene id: 8128:LOC100692650
uniprot id: A0A669BMQ8
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8128:LOC100709042
gene id: 8128:LOC100709042
uniprot id: A0A669BX00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

8128:LOC100702165
gene id: 8128:LOC100702165
uniprot id: I3KGR2
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion

8128:LOC100698323
gene id: 8128:LOC100698323
uniprot id: A0A669BAV6
uniprot id: A0A669BH73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:plk3
gene id: 8128:plk3
uniprot id: I3JUC8
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

8128:LOC100698836
gene id: 8128:LOC100698836
uniprot id: A0A669F8F3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709936
gene id: 8128:LOC100709936
uniprot id: I3JGV0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

8128:LOC100702712
gene id: 8128:LOC100702712
uniprot id: I3JLG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8128:LOC100702742
gene id: 8128:LOC100702742
uniprot id: I3KZW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:aar2
gene id: 8128:aar2
uniprot id: A0A669DBC1
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

8128:LOC100704944
gene id: 8128:LOC100704944
uniprot id: A0A669EIQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

8128:LOC100697787
gene id: 8128:LOC100697787
uniprot id: I3J5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8128:dhx8
gene id: 8128:dhx8
uniprot id: I3KPD5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100691290
gene id: 8128:LOC100691290
uniprot id: I3JM37
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100711584
gene id: 8128:LOC100711584
uniprot id: I3JL52
names: Similarity
messages: Belongs to the myozenin family.

8128:ddx18
gene id: 8128:ddx18
uniprot id: I3JM49
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8128:nuf2
gene id: 8128:nuf2
uniprot id: A0A669DKJ9
names: Similarity
messages: Belongs to the NUF2 family.

8128:LOC100701831
gene id: 8128:LOC100701831
uniprot id: A0A669DXD5
uniprot id: I3KG39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8128:LOC100711895
gene id: 8128:LOC100711895
uniprot id: A0A669DWC8
names: Similarity
messages: Belongs to the p23/wos2 family.

8128:LOC100710449
gene id: 8128:LOC100710449
uniprot id: I3J3L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

8128:LOC102078793
gene id: 8128:LOC102078793
uniprot id: A0A669E677
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8128:LOC100704683
gene id: 8128:LOC100704683
uniprot id: I3J7H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8128:LOC100696919
gene id: 8128:LOC100696919
uniprot id: A0A669EDH0
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8128:LOC100703044
gene id: 8128:LOC100703044
uniprot id: I3KDE4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8128:LOC100705114
gene id: 8128:LOC100705114
uniprot id: I3IVL7
names: Similarity
messages: Belongs to the peptidase C64 family.

8128:LOC100706730
gene id: 8128:LOC100706730
uniprot id: I3JTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8128:LOC100701777
gene id: 8128:LOC100701777
uniprot id: I3IX58
names: Similarity
messages: Belongs to the intermediate filament family.

8128:LOC100694738
gene id: 8128:LOC100694738
uniprot id: I3K7M4
names: Subcellular Location Annotation
messages: Membrane

8128:galnt13
gene id: 8128:galnt13
uniprot id: A0A669CGN5
uniprot id: I3JQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100693336
gene id: 8128:LOC100693336
uniprot id: I3KSW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

8128:rrp8
gene id: 8128:rrp8
uniprot id: I3KJF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Probable methyltransferase required to silence rDNA.
messages: nucleolus

8128:hspd1
gene id: 8128:hspd1
uniprot id: I3K867
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

8128:LOC100711508
gene id: 8128:LOC100711508
uniprot id: A0A669EUJ3
names: Subcellular Location Annotation
messages: cytoskeleton

8128:LOC109203025
gene id: 8128:LOC109203025
uniprot id: A0A669DFM2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100691274
gene id: 8128:LOC100691274
uniprot id: A0A669B478
names: Subcellular Location Annotation
messages: Nucleus

8128:arsb
gene id: 8128:arsb
uniprot id: A0A669BKU0
names: Similarity
messages: Belongs to the sulfatase family.

8128:ildr1
gene id: 8128:ildr1
uniprot id: I3K9M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8128:LOC100707636
gene id: 8128:LOC100707636
uniprot id: I3JGR0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:LOC100708037
gene id: 8128:LOC100708037
uniprot id: A0A669EHJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100705213
gene id: 8128:LOC100705213
uniprot id: I3JRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100704024
gene id: 8128:LOC100704024
uniprot id: I3KFF7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100698131
gene id: 8128:LOC100698131
uniprot id: A0A669BDQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:lpgat1
gene id: 8128:lpgat1
uniprot id: I3JFG7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:mcoln2
gene id: 8128:mcoln2
uniprot id: I3JK73
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8128:eda
gene id: 8128:eda
uniprot id: A0A669DKS2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8128:LOC100710383
gene id: 8128:LOC100710383
uniprot id: A0A669C1J5
uniprot id: I3J1U9
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8128:wasf1
gene id: 8128:wasf1
uniprot id: A0A669CLI9
uniprot id: I3K704
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8128:mnat1
gene id: 8128:mnat1
uniprot id: I3KW45
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

8128:eif4e3
gene id: 8128:eif4e3
uniprot id: I3KWP0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8128:cd81
gene id: 8128:cd81
uniprot id: I3J677
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:bloc1s1
gene id: 8128:bloc1s1
uniprot id: A0A669EH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Mitochondrion intermembrane space

8128:lmod2
gene id: 8128:lmod2
uniprot id: I3K132
names: Subcellular Location Annotation
messages: cytoskeleton

8128:gck
gene id: 8128:gck
uniprot id: A0A669B6D3
names: Similarity
messages: Belongs to the hexokinase family.

8128:KEH09 p05
gene id: 8128:KEH09_p05
uniprot id: D2KP32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

8128:slc35b4
gene id: 8128:slc35b4
uniprot id: A0A669D3J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8128:fzd3
gene id: 8128:fzd3
uniprot id: A0A669B9Q2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC102082805
gene id: 8128:LOC102082805
uniprot id: I3KN46
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100710558
gene id: 8128:LOC100710558
uniprot id: I3KEI2
uniprot id: I3KEI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:dpp3
gene id: 8128:dpp3
uniprot id: I3JPG4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100693977
gene id: 8128:LOC100693977
uniprot id: A0A669AW35
names: Similarity
messages: Belongs to the TPPP family.

8128:LOC100704176
gene id: 8128:LOC100704176
uniprot id: I3KAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

8128:bckdha
gene id: 8128:bckdha
uniprot id: I3J891
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

8128:LOC100708900
gene id: 8128:LOC100708900
uniprot id: A0A669CM67
names: Similarity
messages: Belongs to the peptidase C48 family.

8128:LOC100700298
gene id: 8128:LOC100700298
uniprot id: I3K4S0
names: Similarity
messages: Belongs to the JIP scaffold family.

8128:LOC100701102
gene id: 8128:LOC100701102
uniprot id: I3KNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100702770
gene id: 8128:LOC100702770
uniprot id: A0A669CZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100534419
gene id: 8128:LOC100534419
uniprot id: A7BI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:LOC100702792
gene id: 8128:LOC100702792
uniprot id: A0A669DBU0
uniprot id: A0A669F4J0
uniprot id: I3J9U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8128:chpt1
gene id: 8128:chpt1
uniprot id: I3ITW9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8128:gpr6
gene id: 8128:gpr6
uniprot id: I3KYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100690909
gene id: 8128:LOC100690909
uniprot id: A0A669BQM6
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8128:LOC100699299
gene id: 8128:LOC100699299
uniprot id: A0A669EBK7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100709204
gene id: 8128:LOC100709204
uniprot id: A0A669F2L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:LOC100699266
gene id: 8128:LOC100699266
uniprot id: I3J4Y4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8128:LOC100694196
gene id: 8128:LOC100694196
uniprot id: I3JWD7
names: Similarity
messages: Belongs to the TGF-beta family.

8128:supt6h
gene id: 8128:supt6h
uniprot id: I3JDI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

8128:ap1s3
gene id: 8128:ap1s3
uniprot id: I3KBE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8128:LOC100712014
gene id: 8128:LOC100712014
uniprot id: I3JCD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

8128:alg13
gene id: 8128:alg13
uniprot id: I3JD92
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

8128:pah
gene id: 8128:pah
uniprot id: D4HNR5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8128:fam114a2
gene id: 8128:fam114a2
uniprot id: I3KHX0
names: Similarity
messages: Belongs to the FAM114 family.

8128:LOC100708386
gene id: 8128:LOC100708386
uniprot id: I3J7G7
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:LOC100690407
gene id: 8128:LOC100690407
uniprot id: A0A669BX89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:ca8
gene id: 8128:ca8
uniprot id: I3KIJ6
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

8128:zar1l
gene id: 8128:zar1l
uniprot id: A0A669D0G9
names: Similarity
messages: Belongs to the ZAR1 family.

8128:anxa6
gene id: 8128:anxa6
uniprot id: I3KMK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

8128:taf6
gene id: 8128:taf6
uniprot id: A0A669CHK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8128:LOC100700644
gene id: 8128:LOC100700644
uniprot id: A0A669AW21
names: Similarity
messages: Belongs to the PPDPF family.

8128:mrps10
gene id: 8128:mrps10
uniprot id: A0A669DA60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

8128:LOC100703036
gene id: 8128:LOC100703036
uniprot id: W8G4W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:tm6sf1
gene id: 8128:tm6sf1
uniprot id: I3IUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

8128:cdk2ap1
gene id: 8128:cdk2ap1
uniprot id: A0A669B684
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDK2AP family.
messages: Nucleus

8128:LOC100695832
gene id: 8128:LOC100695832
uniprot id: A0A669E9E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

8128:lg12h12orf49
gene id: 8128:lg12h12orf49
uniprot id: I3JWU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100693944
gene id: 8128:LOC100693944
uniprot id: I3K2A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

8128:LOC100701095
gene id: 8128:LOC100701095
uniprot id: A0A669ESE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:LOC100712328
gene id: 8128:LOC100712328
uniprot id: I3JTY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8128:LOC100707970
gene id: 8128:LOC100707970
uniprot id: A0A669DQG8
uniprot id: A0A669EF20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8128:dhdds
gene id: 8128:dhdds
uniprot id: A0A669EJ01
uniprot id: I3KHI0
names: Similarity
messages: Belongs to the UPP synthase family.

8128:pigv
gene id: 8128:pigv
uniprot id: I3JI45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

8128:xpo5
gene id: 8128:xpo5
uniprot id: I3KQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

8128:cdh7
gene id: 8128:cdh7
uniprot id: A0A669B2P0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8128:LOC100708259
gene id: 8128:LOC100708259
uniprot id: I3JMW3
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8128:pan2
gene id: 8128:pan2
uniprot id: A0A669EX83
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

8128:LOC112841629
gene id: 8128:LOC112841629
uniprot id: I3JBU2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:dhx29
gene id: 8128:dhx29
uniprot id: I3JL17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

8128:LOC100709107
gene id: 8128:LOC100709107
uniprot id: I3JGP8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8128:LOC100698882
gene id: 8128:LOC100698882
uniprot id: A0A669C2Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMN family.
messages: Cajal body
messages: Perikaryon
messages: Z line
messages: gem
messages: neuron projection

8128:cog1
gene id: 8128:cog1
uniprot id: I3JM29
names: Similarity
messages: Belongs to the COG1 family.

8128:ubxn1
gene id: 8128:ubxn1
uniprot id: I3JCR4
names: Subcellular Location Annotation
messages: Cytoplasm

8128:atp4b
gene id: 8128:atp4b
uniprot id: I3J546
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8128:sh2b2
gene id: 8128:sh2b2
uniprot id: I3J7E1
names: Similarity
messages: Belongs to the SH2B adapter family.

8128:LOC100703225
gene id: 8128:LOC100703225
uniprot id: A0A669E7C1
names: Subcellular Location Annotation
messages: centrosome

8128:LOC102077794
gene id: 8128:LOC102077794
uniprot id: A0A669AZF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

8128:pcsk9
gene id: 8128:pcsk9
uniprot id: I3J3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Endosome
messages: Golgi apparatus
messages: Lysosome

8128:bdnf
gene id: 8128:bdnf
uniprot id: I3KXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
messages: Secreted

8128:LOC100712167
gene id: 8128:LOC100712167
uniprot id: I3J8A3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:ccna2
gene id: 8128:ccna2
uniprot id: I3IYJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:LOC100694066
gene id: 8128:LOC100694066
uniprot id: A0A669ESB8
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:gucy1a1
gene id: 8128:gucy1a1
uniprot id: I3KM45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

8128:gth-ri
gene id: 8128:gth-ri
uniprot id: Q9DGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

8128:LOC100700918
gene id: 8128:LOC100700918
uniprot id: I3JS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

8128:ficd
gene id: 8128:ficd
uniprot id: I3K6W5
names: Similarity
messages: Belongs to the fic family.

8128:LOC100691808
gene id: 8128:LOC100691808
uniprot id: A0A669BP91
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8128:LOC100707208
gene id: 8128:LOC100707208
uniprot id: I3JL09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

8128:LOC100699761
gene id: 8128:LOC100699761
uniprot id: A0A669BZ70
names: Similarity
messages: Belongs to the ependymin family.

8128:slc25a28
gene id: 8128:slc25a28
uniprot id: A0A669DXQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:nup133
gene id: 8128:nup133
uniprot id: A0A669E683
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

8128:atpaf2
gene id: 8128:atpaf2
uniprot id: A0A669BUP6
uniprot id: I3KUY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

8128:LOC100701628
gene id: 8128:LOC100701628
uniprot id: A0A669F657
names: Similarity
messages: Belongs to the spectrin family.

8128:polr2f
gene id: 8128:polr2f
uniprot id: A0A669DUC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

8128:LOC100710907
gene id: 8128:LOC100710907
uniprot id: A0A669BBV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100697174
gene id: 8128:LOC100697174
uniprot id: A0A669EQR1
uniprot id: A0A669F2E3
uniprot id: I3IU11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

8128:LOC100708578
gene id: 8128:LOC100708578
uniprot id: I3IY11
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8128:irf2
gene id: 8128:irf2
uniprot id: I3KG09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

8128:polg2
gene id: 8128:polg2
uniprot id: A0A669E0D9
names: Subcellular Location Annotation
messages: Mitochondrion

8128:LOC100704067
gene id: 8128:LOC100704067
uniprot id: I3JPI4
names: Subcellular Location Annotation
messages: cytoskeleton

8128:slc7a14
gene id: 8128:slc7a14
uniprot id: I3IWX6
names: Subcellular Location Annotation
messages: Membrane

8128:atp10d
gene id: 8128:atp10d
uniprot id: I3JZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:LOC100705676
gene id: 8128:LOC100705676
uniprot id: A0A669BUK9
uniprot id: A0A669ET94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8128:cask
gene id: 8128:cask
uniprot id: A0A669CT94
names: Similarity
messages: Belongs to the MAGUK family.

8128:tmem19
gene id: 8128:tmem19
uniprot id: I3KNG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

8128:osgepl1
gene id: 8128:osgepl1
uniprot id: I3KJ85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

8128:LOC100689797
gene id: 8128:LOC100689797
uniprot id: A0A669EKT4
uniprot id: I3KM73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8128:wdr76
gene id: 8128:wdr76
uniprot id: I3J2W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8128:mcm10
gene id: 8128:mcm10
uniprot id: I3K175
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

8128:brox
gene id: 8128:brox
uniprot id: I3IYJ7
names: Similarity
messages: Belongs to the BROX family.

8128:LOC100698283
gene id: 8128:LOC100698283
uniprot id: A0A669C4T1
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

8128:itga2
gene id: 8128:itga2
uniprot id: A0A669CNL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100705310
gene id: 8128:LOC100705310
uniprot id: I3JE28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

8128:rpl18
gene id: 8128:rpl18
uniprot id: P69091
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: Cytoplasm
messages: Rough endoplasmic reticulum
messages: cytosol

8128:LOC100707324
gene id: 8128:LOC100707324
uniprot id: I3IXE9
uniprot id: I3IXF0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8128:ust
gene id: 8128:ust
uniprot id: A0A669BP65
uniprot id: I3K6Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:cdh2
gene id: 8128:cdh2
uniprot id: A0A669E1S6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8128:LOC100693325
gene id: 8128:LOC100693325
uniprot id: A0A669ECK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:rps25
gene id: 8128:rps25
uniprot id: A0A669E4L2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

8128:LOC100698585
gene id: 8128:LOC100698585
uniprot id: A0A669EEP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8128:elp3
gene id: 8128:elp3
uniprot id: A0A669BCC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

8128:LOC100690282
gene id: 8128:LOC100690282
uniprot id: I3K0W3
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100703919
gene id: 8128:LOC100703919
uniprot id: I3J3V3
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100698681
gene id: 8128:LOC100698681
uniprot id: A0A669CA03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

8128:LOC100712109
gene id: 8128:LOC100712109
uniprot id: I3JRE5
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:kiaa1324
gene id: 8128:kiaa1324
uniprot id: A0A669C5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8128:LOC100690466
gene id: 8128:LOC100690466
uniprot id: I3JPV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:LOC100702797
gene id: 8128:LOC100702797
uniprot id: A0A669CK52
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8128:LOC100690289
gene id: 8128:LOC100690289
uniprot id: I3KCG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8128:hdx
gene id: 8128:hdx
uniprot id: I3KMC5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC109194293
gene id: 8128:LOC109194293
uniprot id: I3KPF0
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8128:LOC100707401
gene id: 8128:LOC100707401
uniprot id: A0A669E906
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:aqp9
gene id: 8128:aqp9
uniprot id: I3JEP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:LOC100696843
gene id: 8128:LOC100696843
uniprot id: A0A669CIE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:ppil6
gene id: 8128:ppil6
uniprot id: A0A669CP05
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:LOC100706881
gene id: 8128:LOC100706881
uniprot id: I3K043
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

8128:LOC109194297
gene id: 8128:LOC109194297
uniprot id: A0A669BNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:LOC100700092
gene id: 8128:LOC100700092
uniprot id: A0A669CG28
names: Similarity
messages: Belongs to the requiem/DPF family.

8128:LOC100708525
gene id: 8128:LOC100708525
uniprot id: I3KME3
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

8128:LOC100702144
gene id: 8128:LOC100702144
uniprot id: A0A669CQJ1
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC100709697
gene id: 8128:LOC100709697
uniprot id: I3JUD1
names: Similarity
messages: Belongs to the DENND11 family.

8128:LOC100691280
gene id: 8128:LOC100691280
uniprot id: I3KVL0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:hoxd3
gene id: 8128:hoxd3
uniprot id: I3JPN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:LOC100707505
gene id: 8128:LOC100707505
uniprot id: I3KV10
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8128:LOC100701390
gene id: 8128:LOC100701390
uniprot id: I3K6L1
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

8128:msh6
gene id: 8128:msh6
uniprot id: A0A669CZS1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

8128:slc52a3
gene id: 8128:slc52a3
uniprot id: I3KJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8128:LOC100710775
gene id: 8128:LOC100710775
uniprot id: I3KZV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100695267
gene id: 8128:LOC100695267
uniprot id: A0A669B6V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8128:LOC100705341
gene id: 8128:LOC100705341
uniprot id: A0A669B767
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:hdac10
gene id: 8128:hdac10
uniprot id: I3JQB4
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

8128:LOC100692969
gene id: 8128:LOC100692969
uniprot id: A0A669BUY4
uniprot id: A0A669CVK4
uniprot id: A0A669DKU5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

8128:LOC102083175
gene id: 8128:LOC102083175
uniprot id: I3J1B7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100712331
gene id: 8128:LOC100712331
uniprot id: A0A669EL51
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8128:LOC100704272
gene id: 8128:LOC100704272
uniprot id: A0A669AXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8128:LOC100709627
gene id: 8128:LOC100709627
uniprot id: I3JMD9
names: Subcellular Location Annotation
messages: cytoskeleton

8128:LOC100703683
gene id: 8128:LOC100703683
uniprot id: A0A669BUK6
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100699409
gene id: 8128:LOC100699409
uniprot id: I3KL27
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

8128:ptges2
gene id: 8128:ptges2
uniprot id: I3K8V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

8128:LOC100694444
gene id: 8128:LOC100694444
uniprot id: A0A669F7A8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8128:LOC100701843
gene id: 8128:LOC100701843
uniprot id: I3K6G4
names: Similarity
messages: Belongs to the SLA2 family.

8128:LOC100709447
gene id: 8128:LOC100709447
uniprot id: I3JL75
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

8128:ccser1
gene id: 8128:ccser1
uniprot id: I3KCV3
names: Similarity
messages: Belongs to the CCSER family.

8128:LOC100708533
gene id: 8128:LOC100708533
uniprot id: I3K7G4
names: Similarity
messages: Belongs to the annexin family.

8128:tradd
gene id: 8128:tradd
uniprot id: I3JED3
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

8128:LOC100700167
gene id: 8128:LOC100700167
uniprot id: I3KC99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8128:ccdc126
gene id: 8128:ccdc126
uniprot id: A0A669BS01
names: Subcellular Location Annotation
messages: Secreted

8128:pex5
gene id: 8128:pex5
uniprot id: A0A669DLL8
uniprot id: A0A669F199
uniprot id: I3K5E4
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

8128:fgfrl1
gene id: 8128:fgfrl1
uniprot id: I3IXH5
names: Subcellular Location Annotation
messages: Membrane

8128:tmem214
gene id: 8128:tmem214
uniprot id: I3JDL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:arl4c
gene id: 8128:arl4c
uniprot id: A0A669BQK1
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8128:LOC100698818
gene id: 8128:LOC100698818
uniprot id: A0A669BKK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8128:LOC100695799
gene id: 8128:LOC100695799
uniprot id: I3KNE1
uniprot id: I3KNE2
names: Similarity
messages: Belongs to the serpin family.
messages: Belongs to the serpin family. Ov-serpin subfamily.

8128:LOC100700371
gene id: 8128:LOC100700371
uniprot id: I3JN02
names: Subcellular Location Annotation
messages: Nucleus

8128:xpa
gene id: 8128:xpa
uniprot id: I3KH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

8128:shank2
gene id: 8128:shank2
uniprot id: A0A669DYU7
uniprot id: A0A669DZI1
names: Similarity
messages: Belongs to the MAGUK family.

8128:LOC100691614
gene id: 8128:LOC100691614
uniprot id: A0A669ET14
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100706356
gene id: 8128:LOC100706356
uniprot id: I3K4S2
names: Similarity
messages: Belongs to the GADD45 family.

8128:cacng3
gene id: 8128:cacng3
uniprot id: I3KF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8128:top2a
gene id: 8128:top2a
uniprot id: I3KVE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

8128:LOC100693502
gene id: 8128:LOC100693502
uniprot id: A0A669BQC0
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

8128:fgf6
gene id: 8128:fgf6
uniprot id: A0A669C7A9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:LOC100690432
gene id: 8128:LOC100690432
uniprot id: I3KIT5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100703321
gene id: 8128:LOC100703321
uniprot id: I3K064
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8128:abl2
gene id: 8128:abl2
uniprot id: A0A669D9Q2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:LOC100705178
gene id: 8128:LOC100705178
uniprot id: I3K8Q6
names: Similarity
messages: Belongs to the NifU family.

8128:ctdp1
gene id: 8128:ctdp1
uniprot id: A0A669D1Q4
uniprot id: I3JLE3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

8128:slc39a4
gene id: 8128:slc39a4
uniprot id: I3KUY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

8128:LOC109198965
gene id: 8128:LOC109198965
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:nkx6-3
gene id: 8128:nkx6-3
uniprot id: A0A669CJT3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709246
gene id: 8128:LOC100709246
uniprot id: A0A669BND1
uniprot id: A0A669DV09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

8128:LOC100691326
gene id: 8128:LOC100691326
uniprot id: A0A669AVN6
names: Similarity
messages: Belongs to the PPDPF family.

8128:LOC100691234
gene id: 8128:LOC100691234
uniprot id: A0A669DD04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:fez2
gene id: 8128:fez2
uniprot id: A0A669BUQ6
uniprot id: A0A669EQY6
names: Similarity
messages: Belongs to the zygin family.

8128:imp3
gene id: 8128:imp3
uniprot id: A0A669C9X1
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

8128:yif1b
gene id: 8128:yif1b
uniprot id: I3JBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

8128:gipc2
gene id: 8128:gipc2
uniprot id: I3KPZ0
names: Similarity
messages: Belongs to the GIPC family.

8128:LOC100707138
gene id: 8128:LOC100707138
uniprot id: I3IZ87
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

8128:ate1
gene id: 8128:ate1
uniprot id: I3JVB2
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

8128:LOC100700713
gene id: 8128:LOC100700713
uniprot id: A0A669C956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cytoplasm
messages: Postsynaptic density

8128:LOC100702766
gene id: 8128:LOC100702766
uniprot id: A0A669B7E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:ercc2
gene id: 8128:ercc2
uniprot id: I3JLJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

8128:LOC102079696
gene id: 8128:LOC102079696
uniprot id: I3J7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100707592
gene id: 8128:LOC100707592
uniprot id: A0A669EZA8
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

8128:ezh1
gene id: 8128:ezh1
uniprot id: I3IY40
names: Subcellular Location Annotation
messages: Nucleus

8128:sepsecs
gene id: 8128:sepsecs
uniprot id: A0A669BGV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

8128:srpx
gene id: 8128:srpx
uniprot id: A0A669DWU5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100700987
gene id: 8128:LOC100700987
uniprot id: I3KTP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

8128:LOC100712567
gene id: 8128:LOC100712567
uniprot id: I3J1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8128:LOC100694190
gene id: 8128:LOC100694190
uniprot id: A0A669CXJ7
uniprot id: I3J7G4
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8128:ccdc153
gene id: 8128:ccdc153
uniprot id: I3JG34
names: Similarity
messages: Belongs to the UPF0610 family.

8128:LOC100702381
gene id: 8128:LOC100702381
uniprot id: A0A669DEX5
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:lamc2
gene id: 8128:lamc2
uniprot id: I3IUS3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

8128:LOC100693117
gene id: 8128:LOC100693117
uniprot id: A0A669BKN4
uniprot id: A0A669C0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8128:LOC109197509
gene id: 8128:LOC109197509
uniprot id: I3KI30
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC102078694
gene id: 8128:LOC102078694
uniprot id: A0A669FCR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: Vacuole membrane

8128:senp8
gene id: 8128:senp8
uniprot id: I3KXA8
names: Similarity
messages: Belongs to the peptidase C48 family.

8128:LOC100692475
gene id: 8128:LOC100692475
uniprot id: I3ITX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

8128:tm7sf3
gene id: 8128:tm7sf3
uniprot id: A0A669BLE5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100705874
gene id: 8128:LOC100705874
uniprot id: I3JAT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC106097938
gene id: 8128:LOC106097938
uniprot id: A0A669F583
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8128:ftsj3
gene id: 8128:ftsj3
uniprot id: I3IZN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

8128:penk
gene id: 8128:penk
uniprot id: A0A669F4Q2
names: Similarity
messages: Belongs to the opioid neuropeptide precursor family.

8128:LOC100701299
gene id: 8128:LOC100701299
uniprot id: A0A669CQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

8128:clcn1
gene id: 8128:clcn1
uniprot id: I3K514
names: Subcellular Location Annotation
messages: Membrane

8128:snx8
gene id: 8128:snx8
uniprot id: I3IYH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8128:gldn
gene id: 8128:gldn
uniprot id: I3IUA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:zbtb8os
gene id: 8128:zbtb8os
uniprot id: I3K2Q3
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

8128:LOC100703904
gene id: 8128:LOC100703904
uniprot id: I3IZZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

8128:LOC100705733
gene id: 8128:LOC100705733
uniprot id: A0A669CBU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTC1 family.
messages: Nucleus
messages: telomere

8128:lbh
gene id: 8128:lbh
uniprot id: A0A669DNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100702113
gene id: 8128:LOC100702113
uniprot id: I3JG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

8128:LOC100690958
gene id: 8128:LOC100690958
uniprot id: I3J7E8
uniprot id: I3J7E9
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8128:hmbox1
gene id: 8128:hmbox1
uniprot id: I3IYI8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100699530
gene id: 8128:LOC100699530
uniprot id: A0A669B1M0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC106098018
gene id: 8128:LOC106098018
uniprot id: A0A669FB89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCO1/2 family.
messages: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
messages: Homodimer.
messages: Mitochondrion inner membrane

8128:recql
gene id: 8128:recql
uniprot id: A0A669EVQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

8128:LOC100706349
gene id: 8128:LOC100706349
uniprot id: A0A669BT37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:anp32a
gene id: 8128:anp32a
uniprot id: A0A669BFJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

8128:LOC100699925
gene id: 8128:LOC100699925
uniprot id: I3J618
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

8128:rpl9
gene id: 8128:rpl9
uniprot id: I3JR13
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

8128:LOC100706415
gene id: 8128:LOC100706415
uniprot id: I3JX90
names: Similarity
messages: Belongs to the intermediate filament family.

8128:LOC100695234
gene id: 8128:LOC100695234
uniprot id: I3J1Q4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8128:LOC100693544
gene id: 8128:LOC100693544
uniprot id: I3J0P9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704738
gene id: 8128:LOC100704738
uniprot id: I3JR17
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:sgsm1
gene id: 8128:sgsm1
uniprot id: A0A669C7Z7
uniprot id: A0A669D3A0
names: Similarity
messages: Belongs to the RUTBC family.

8128:LOC100706449
gene id: 8128:LOC100706449
uniprot id: A0A669F7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

8128:myo1b
gene id: 8128:myo1b
uniprot id: I3J9C5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:brpf1
gene id: 8128:brpf1
uniprot id: A0A669F8N4
names: Subcellular Location Annotation
messages: Nucleus

8128:nln
gene id: 8128:nln
uniprot id: A0A669CXA2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

8128:LOC100691068
gene id: 8128:LOC100691068
uniprot id: I3JUI6
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:adhfe1
gene id: 8128:adhfe1
uniprot id: I3IVJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

8128:LOC100690194
gene id: 8128:LOC100690194
uniprot id: A0A669BPD2
names: Similarity
messages: Belongs to the TMEM178 family.

8128:abcc5
gene id: 8128:abcc5
uniprot id: I3K8R5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710114
gene id: 8128:LOC100710114
uniprot id: I3KXL9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100705259
gene id: 8128:LOC100705259
uniprot id: I3JIP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8128:LOC100711960
gene id: 8128:LOC100711960
uniprot id: I3J0M7
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:idi1
gene id: 8128:idi1
uniprot id: A0A669CU46
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

8128:LOC100705953
gene id: 8128:LOC100705953
uniprot id: A0A669ESI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:LOC109204255
gene id: 8128:LOC109204255
uniprot id: A0A669D429
uniprot id: I3ITW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8128:rc3h1
gene id: 8128:rc3h1
uniprot id: I3JUH9
names: Subcellular Location Annotation
messages: P-body

8128:plcd3
gene id: 8128:plcd3
uniprot id: I3IWV2
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

8128:rragc
gene id: 8128:rragc
uniprot id: A0A669ED65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

8128:LOC100697579
gene id: 8128:LOC100697579
uniprot id: I3JEH6
names: Similarity
messages: Belongs to the cystatin family.

8128:chst2
gene id: 8128:chst2
uniprot id: I3KXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:LOC100709160
gene id: 8128:LOC100709160
uniprot id: A0A669C8A6
uniprot id: A0A669D5D0
names: Subcellular Location Annotation
messages: Membrane

8128:ap1s1
gene id: 8128:ap1s1
uniprot id: A0A669BVU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8128:LOC100697735
gene id: 8128:LOC100697735
uniprot id: I3IUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100691998
gene id: 8128:LOC100691998
uniprot id: A0A669CYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:LOC100695261
gene id: 8128:LOC100695261
uniprot id: I3JWG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:LOC100712274
gene id: 8128:LOC100712274
uniprot id: I3JLB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:tsg101
gene id: 8128:tsg101
uniprot id: I3KB16
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

8128:blmh
gene id: 8128:blmh
uniprot id: A0A669EEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

8128:LOC100693885
gene id: 8128:LOC100693885
uniprot id: A0A075FJ48
uniprot id: I3KFQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8128:LOC100700758
gene id: 8128:LOC100700758
uniprot id: A0A669EZZ6
uniprot id: I3KFJ1
names: Similarity
messages: Belongs to the phospholipase D family.

8128:cd82
gene id: 8128:cd82
uniprot id: I3JP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100700821
gene id: 8128:LOC100700821
uniprot id: A0A669B5Z3
names: Subcellular Location Annotation
messages: Membrane

8128:nipal2
gene id: 8128:nipal2
uniprot id: A0A669F4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8128:LOC100711384
gene id: 8128:LOC100711384
uniprot id: I3J514
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100698845
gene id: 8128:LOC100698845
uniprot id: I3J1G1
names: Similarity
messages: Belongs to the RimK family.

8128:LOC100690027
gene id: 8128:LOC100690027
uniprot id: A0A669FBX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8128:ndufs7
gene id: 8128:ndufs7
uniprot id: I3K4B9
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

8128:LOC100692145
gene id: 8128:LOC100692145
uniprot id: A0A669CVT6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100702967
gene id: 8128:LOC100702967
uniprot id: I3KAU6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8128:LOC100703576
gene id: 8128:LOC100703576
uniprot id: A0A669DZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:ramac
gene id: 8128:ramac
uniprot id: A0A669BK11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAM family.
messages: Nucleus

8128:LOC100708619
gene id: 8128:LOC100708619
uniprot id: A0A669CEZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:LOC100693668
gene id: 8128:LOC100693668
uniprot id: I3JYB3
names: Subcellular Location Annotation
messages: Nucleus

8128:sema3e
gene id: 8128:sema3e
uniprot id: I3KCJ0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100702124
gene id: 8128:LOC100702124
uniprot id: I3KJZ7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100708800
gene id: 8128:LOC100708800
uniprot id: A0A669BPP8
uniprot id: A0A669D4P0
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

8128:fgb
gene id: 8128:fgb
uniprot id: I3K9D6
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

8128:LOC100710041
gene id: 8128:LOC100710041
uniprot id: A0A669C472
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

8128:LOC100703499
gene id: 8128:LOC100703499
uniprot id: I3JXZ8
names: Subcellular Location Annotation
messages: Membrane

8128:cdr2
gene id: 8128:cdr2
uniprot id: I3KFQ5
names: Similarity
messages: Belongs to the CDR2 family.

8128:ero1b
gene id: 8128:ero1b
uniprot id: I3KP10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

8128:LOC100692709
gene id: 8128:LOC100692709
uniprot id: I3IYM2
names: Similarity
messages: Belongs to the yippee family.

8128:LOC100703625
gene id: 8128:LOC100703625
uniprot id: I3J8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: dendrite
messages: sarcolemma
messages: synaptosome

8128:igsf11
gene id: 8128:igsf11
uniprot id: I3KIT8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710113
gene id: 8128:LOC100710113
uniprot id: I3KIL5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.

8128:btbd10
gene id: 8128:btbd10
uniprot id: A0A669F4J3
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC106097128
gene id: 8128:LOC106097128
uniprot id: A0A669C870
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:cpq
gene id: 8128:cpq
uniprot id: A0A669DW22
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome

8128:sfrp5
gene id: 8128:sfrp5
uniprot id: I3KPS6
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100697313
gene id: 8128:LOC100697313
uniprot id: I3KL25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:chdh
gene id: 8128:chdh
uniprot id: I3J0B7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

8128:LOC100690964
gene id: 8128:LOC100690964
uniprot id: I3K0C7
names: Similarity
messages: Belongs to the TACO1 family.

8128:LOC100706716
gene id: 8128:LOC100706716
uniprot id: A0A669CUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

8128:dpy19l1
gene id: 8128:dpy19l1
uniprot id: I3JHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

8128:fcho2
gene id: 8128:fcho2
uniprot id: A0A669DXZ7
uniprot id: A0A669EFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

8128:LOC100706669
gene id: 8128:LOC100706669
uniprot id: A0A669CBV1
uniprot id: A0A669F636
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:LOC100695063
gene id: 8128:LOC100695063
uniprot id: I3KBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8128:LOC102076855
gene id: 8128:LOC102076855
uniprot id: I3J5W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8128:pomc
gene id: 8128:pomc
uniprot id: I3KR43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8128:LOC100697118
gene id: 8128:LOC100697118
uniprot id: I3KJ68
names: Subcellular Location Annotation
messages: Membrane

8128:orc5
gene id: 8128:orc5
uniprot id: I3IU31
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100697423
gene id: 8128:LOC100697423
uniprot id: I3KR48
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

8128:LOC100692580
gene id: 8128:LOC100692580
uniprot id: I3JUY5
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

8128:mcm9
gene id: 8128:mcm9
uniprot id: A0A669B0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8128:LOC100698455
gene id: 8128:LOC100698455
uniprot id: I3KJ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8128:LOC100703595
gene id: 8128:LOC100703595
uniprot id: A0A669DFH2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100706200
gene id: 8128:LOC100706200
uniprot id: I3IY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8128:gtf2b
gene id: 8128:gtf2b
uniprot id: I3JWS6
names: Similarity
messages: Belongs to the TFIIB family.

8128:LOC100707350
gene id: 8128:LOC100707350
uniprot id: I3JDB0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8128:dbr1
gene id: 8128:dbr1
uniprot id: I3K8B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

8128:LOC100702966
gene id: 8128:LOC100702966
uniprot id: I3K3X1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:taf2
gene id: 8128:taf2
uniprot id: I3JMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

8128:reep3
gene id: 8128:reep3
uniprot id: A0A669EQL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8128:ganab
gene id: 8128:ganab
uniprot id: A0A669C319
uniprot id: I3JCS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8128:LOC100690303
gene id: 8128:LOC100690303
uniprot id: I3K1Z5
names: Similarity
messages: Belongs to the caprin family.

8128:ikbke
gene id: 8128:ikbke
uniprot id: I3KT33
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100697795
gene id: 8128:LOC100697795
uniprot id: I3K3I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100705720
gene id: 8128:LOC100705720
uniprot id: I3JBV7
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:chd8
gene id: 8128:chd8
uniprot id: I3KEP6
uniprot id: I3KEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. CHD8 subfamily.
messages: Component of some MLL1/MLL complex.
messages: DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. May also act as a transcription activator by participating in efficient U6 RNA polymerase III transcription.
messages: Nucleus

8128:arrdc1
gene id: 8128:arrdc1
uniprot id: I3K5B9
names: Similarity
messages: Belongs to the arrestin family.

8128:scrn2
gene id: 8128:scrn2
uniprot id: I3J5E6
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

8128:LOC102079507
gene id: 8128:LOC102079507
uniprot id: A0A669CD08
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100695043
gene id: 8128:LOC100695043
uniprot id: I3JRM9
uniprot id: I3JRN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100705868
gene id: 8128:LOC100705868
uniprot id: I3J8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:pnn
gene id: 8128:pnn
uniprot id: A0A669CZ01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

8128:LOC100704279
gene id: 8128:LOC100704279
uniprot id: I3KQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8128:ociad1
gene id: 8128:ociad1
uniprot id: I3KNH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

8128:LOC109196021
gene id: 8128:LOC109196021
uniprot id: A0A669EVE9
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

8128:LOC102078936
gene id: 8128:LOC102078936
uniprot id: A0A669DB78
uniprot id: A0A669EUU8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: interphotoreceptor matrix

8128:LOC100709536
gene id: 8128:LOC100709536
uniprot id: I3JZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:LOC100702425
gene id: 8128:LOC100702425
uniprot id: I3JH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:LOC100699532
gene id: 8128:LOC100699532
uniprot id: A0A669DGK5
uniprot id: I3KJT8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100711555
gene id: 8128:LOC100711555
uniprot id: I3JTQ3
names: Subcellular Location Annotation
messages: Membrane

8128:vegfc
gene id: 8128:vegfc
uniprot id: I3KVX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

8128:babam1
gene id: 8128:babam1
uniprot id: I3JV16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

8128:LOC100705343
gene id: 8128:LOC100705343
uniprot id: I3L010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:LOC100711712
gene id: 8128:LOC100711712
uniprot id: A0A669DCU4
uniprot id: I3KAX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100696600
gene id: 8128:LOC100696600
uniprot id: A0A669BC22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

8128:mrps30
gene id: 8128:mrps30
uniprot id: A0A669D771
names: Subcellular Location Annotation
messages: Mitochondrion

8128:LOC100705716
gene id: 8128:LOC100705716
uniprot id: I3K4I3
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:LOC100692761
gene id: 8128:LOC100692761
uniprot id: A0A669D1R1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696811
gene id: 8128:LOC100696811
uniprot id: A0A669BCH6
uniprot id: A0A669E246
uniprot id: A0A669E701
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

8128:LOC100698402
gene id: 8128:LOC100698402
uniprot id: I3JH26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:LOC100692150
gene id: 8128:LOC100692150
uniprot id: A0A669F6L1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8128:tmem106b
gene id: 8128:tmem106b
uniprot id: I3JH96
names: Similarity
messages: Belongs to the TMEM106 family.

8128:snx2
gene id: 8128:snx2
uniprot id: A0A669DBH2
names: Similarity
messages: Belongs to the sorting nexin family.

8128:LOC100701787
gene id: 8128:LOC100701787
uniprot id: A0A669ETU4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:acap2
gene id: 8128:acap2
uniprot id: A0A669DKH3
uniprot id: I3J300
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8128:LOC100701658
gene id: 8128:LOC100701658
uniprot id: I3KJC8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100711168
gene id: 8128:LOC100711168
uniprot id: I3IYI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

8128:lg7h15orf40
gene id: 8128:lg7h15orf40
uniprot id: I3J8M6
names: Similarity
messages: Belongs to the UPF0235 family.

8128:LOC100710671
gene id: 8128:LOC100710671
uniprot id: I3K4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:piwil1
gene id: 8128:piwil1
uniprot id: I3JY33
names: Similarity
messages: Belongs to the argonaute family.

8128:rmi1
gene id: 8128:rmi1
uniprot id: A0A669CIW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

8128:tmem17
gene id: 8128:tmem17
uniprot id: I3JWC7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699275
gene id: 8128:LOC100699275
uniprot id: I3IYR3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:golm1
gene id: 8128:golm1
uniprot id: I3KCK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

8128:hao1
gene id: 8128:hao1
uniprot id: I3J654
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

8128:LOC100708831
gene id: 8128:LOC100708831
uniprot id: A0A669AX01
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100695886
gene id: 8128:LOC100695886
uniprot id: I3JUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8128:LOC100696470
gene id: 8128:LOC100696470
uniprot id: A0A669CHL7
names: Subcellular Location Annotation
messages: Nucleus

8128:pepd
gene id: 8128:pepd
uniprot id: I3J430
names: Similarity
messages: Belongs to the peptidase M24B family.

8128:ntsr1
gene id: 8128:ntsr1
uniprot id: A0A669CIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC102080248
gene id: 8128:LOC102080248
uniprot id: A0A669F677
names: Subcellular Location Annotation
messages: Membrane

8128:metap1d
gene id: 8128:metap1d
uniprot id: I3JW05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

8128:LOC102075787
gene id: 8128:LOC102075787
uniprot id: A0A669DJI1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709367
gene id: 8128:LOC100709367
uniprot id: I3KJS5
names: Subcellular Location Annotation
messages: Membrane

8128:pdcl3
gene id: 8128:pdcl3
uniprot id: A0A669DI36
names: Similarity
messages: Belongs to the phosducin family.

8128:LOC100689726
gene id: 8128:LOC100689726
uniprot id: A0A669CCR9
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

8128:cyp17a2
gene id: 8128:cyp17a2
uniprot id: A7TVD1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:phb
gene id: 8128:phb
uniprot id: I3IX27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

8128:vamp4
gene id: 8128:vamp4
uniprot id: I3J3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8128:LOC100694516
gene id: 8128:LOC100694516
uniprot id: I3JRM6
names: Similarity
messages: Belongs to the copine family.

8128:LOC100706574
gene id: 8128:LOC100706574
uniprot id: I3J4B7
names: Similarity
messages: Belongs to the intermediate filament family.

8128:vill
gene id: 8128:vill
uniprot id: I3JEN1
names: Similarity
messages: Belongs to the villin/gelsolin family.

8128:hoxd9
gene id: 8128:hoxd9
uniprot id: A0A669C5A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:LOC100709153
gene id: 8128:LOC100709153
uniprot id: A0A669D1E0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699487
gene id: 8128:LOC100699487
uniprot id: I3KSG6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699687
gene id: 8128:LOC100699687
uniprot id: A0A669BUY8
names: Similarity
messages: Belongs to the intermediate filament family.

8128:LOC102083311
gene id: 8128:LOC102083311
uniprot id: A0A669E3W2
names: Similarity
messages: Belongs to the TMEM121 family.

8128:LOC100705560
gene id: 8128:LOC100705560
uniprot id: I3JZL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

8128:met
gene id: 8128:met
uniprot id: A0A669F733
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100690009
gene id: 8128:LOC100690009
uniprot id: I3KAR3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:ttc36
gene id: 8128:ttc36
uniprot id: I3JEF5
names: Similarity
messages: Belongs to the TTC36 family.

8128:LOC100710535
gene id: 8128:LOC100710535
uniprot id: I3JB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:camkmt
gene id: 8128:camkmt
uniprot id: A0A669F3T6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:pik3c3
gene id: 8128:pik3c3
uniprot id: A0A669DIB6
uniprot id: I3K560
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8128:ids
gene id: 8128:ids
uniprot id: A0A669DGC3
names: Similarity
messages: Belongs to the sulfatase family.

8128:mmaa
gene id: 8128:mmaa
uniprot id: I3JUN4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

8128:LOC100690985
gene id: 8128:LOC100690985
uniprot id: I3KD65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

8128:scube1
gene id: 8128:scube1
uniprot id: I3K1V8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:prmt5
gene id: 8128:prmt5
uniprot id: A0A669EQ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

8128:LOC100690070
gene id: 8128:LOC100690070
uniprot id: A0A669CVD1
names: Similarity
messages: Belongs to the cyclin family.

8128:cacnb2
gene id: 8128:cacnb2
uniprot id: A0A669BN02
uniprot id: A0A669C4P3
uniprot id: A0A669DIL3
uniprot id: I3JFG5
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

8128:LOC100711148
gene id: 8128:LOC100711148
uniprot id: A0A669CPM5
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100695849
gene id: 8128:LOC100695849
uniprot id: I3IZX7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8128:fzd6
gene id: 8128:fzd6
uniprot id: I3IU79
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100711761
gene id: 8128:LOC100711761
uniprot id: I3KIH0
names: Subcellular Location Annotation
messages: Nucleus

8128:nr1i2
gene id: 8128:nr1i2
uniprot id: I3KAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:odc1
gene id: 8128:odc1
uniprot id: I3KU18
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

8128:LOC109203860
gene id: 8128:LOC109203860
uniprot id: I3JPD5
names: Subcellular Location Annotation
messages: Membrane

8128:slc6a20
gene id: 8128:slc6a20
uniprot id: A0A669CBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:kcnj5
gene id: 8128:kcnj5
uniprot id: I3JCW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

8128:LOC100694813
gene id: 8128:LOC100694813
uniprot id: I3KJY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8128:LOC100699163
gene id: 8128:LOC100699163
uniprot id: I3K6I5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100693655
gene id: 8128:LOC100693655
uniprot id: I3JW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

8128:arap2
gene id: 8128:arap2
uniprot id: I3JS02
names: Subcellular Location Annotation
messages: Cytoplasm

8128:sntg1
gene id: 8128:sntg1
uniprot id: I3JSY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

8128:wdr18
gene id: 8128:wdr18
uniprot id: I3JA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Dynein axonemal particle
messages: nucleolus
messages: nucleoplasm

8128:ssx2ip
gene id: 8128:ssx2ip
uniprot id: I3JK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

8128:LOC100705492
gene id: 8128:LOC100705492
uniprot id: I3KU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:tnfrsf1a
gene id: 8128:tnfrsf1a
uniprot id: A0A0B5GPU3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100702008
gene id: 8128:LOC100702008
uniprot id: I3JAU9
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8128:LOC102079417
gene id: 8128:LOC102079417
uniprot id: I3KR61
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100708437
gene id: 8128:LOC100708437
uniprot id: I3J5F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100702434
gene id: 8128:LOC100702434
uniprot id: A0A669CWX8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:creg2
gene id: 8128:creg2
uniprot id: I3K9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

8128:LOC100707770
gene id: 8128:LOC100707770
uniprot id: I3JU54
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

8128:LOC100694913
gene id: 8128:LOC100694913
uniprot id: A0A669D125
uniprot id: A0A669F021
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8128:pus1
gene id: 8128:pus1
uniprot id: I3J7E3
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8128:gpr183
gene id: 8128:gpr183
uniprot id: I3KXE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:etfa
gene id: 8128:etfa
uniprot id: A0A669E2N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

8128:irak1bp1
gene id: 8128:irak1bp1
uniprot id: I3IXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100695684
gene id: 8128:LOC100695684
uniprot id: I3JJT5
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100700322
gene id: 8128:LOC100700322
uniprot id: A0A669EG49
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100704746
gene id: 8128:LOC100704746
uniprot id: A0A669E9U0
uniprot id: I3J534
names: Subcellular Location Annotation
messages: Membrane

8128:ints12
gene id: 8128:ints12
uniprot id: I3KLV8
names: Similarity
messages: Belongs to the Integrator subunit 12 family.

8128:LOC102075686
gene id: 8128:LOC102075686
uniprot id: A0A669BN15
uniprot id: A0A669DD42
names: Subcellular Location Annotation
messages: Nucleus

8128:mpped1
gene id: 8128:mpped1
uniprot id: A0A669E4A6
names: Similarity
messages: Belongs to the UPF0046 family.

8128:LOC109204553
gene id: 8128:LOC109204553
uniprot id: A0A669D5J1
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100698737
gene id: 8128:LOC100698737
uniprot id: A0A669DPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:sumf1
gene id: 8128:sumf1
uniprot id: A0A669CY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

8128:LOC100710487
gene id: 8128:LOC100710487
uniprot id: A0A669AYM9
uniprot id: I3JQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:bpgm
gene id: 8128:bpgm
uniprot id: A0A669B5S7
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8128:timm8b
gene id: 8128:timm8b
uniprot id: A0A669DYK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8128:irx6
gene id: 8128:irx6
uniprot id: A0A669BKI9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100695665
gene id: 8128:LOC100695665
uniprot id: I3KQL4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8128:slc33a1
gene id: 8128:slc33a1
uniprot id: I3JDJ3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100698349
gene id: 8128:LOC100698349
uniprot id: A0A669F420
names: Subcellular Location Annotation
messages: Nucleus

8128:pnpo
gene id: 8128:pnpo
uniprot id: A0A669F7E4
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

8128:nudt6
gene id: 8128:nudt6
uniprot id: A0A669DCI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

8128:tubg1
gene id: 8128:tubg1
uniprot id: I3IY83
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

8128:LOC100699963
gene id: 8128:LOC100699963
uniprot id: A0A669D2Q1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC102077990
gene id: 8128:LOC102077990
uniprot id: I3KDE3
names: Subcellular Location Annotation
messages: Membrane

8128:serpina10
gene id: 8128:serpina10
uniprot id: I3KW84
names: Similarity
messages: Belongs to the serpin family.

8128:cdkl1
gene id: 8128:cdkl1
uniprot id: I3IVH5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100711582
gene id: 8128:LOC100711582
uniprot id: I3KHI4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:tmlhe
gene id: 8128:tmlhe
uniprot id: I3J090
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

8128:seh1l
gene id: 8128:seh1l
uniprot id: A0A669CEZ0
uniprot id: I3JIK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

8128:alg14
gene id: 8128:alg14
uniprot id: I3JTE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

8128:tmem242
gene id: 8128:tmem242
uniprot id: A0A669F2N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

8128:triap1
gene id: 8128:triap1
uniprot id: I3KYQ9
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

8128:ormdl1
gene id: 8128:ormdl1
uniprot id: I3KPD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8128:pdxp
gene id: 8128:pdxp
uniprot id: A0A669B1B3
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

8128:pik3cg
gene id: 8128:pik3cg
uniprot id: A0A669D155
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8128:LOC100695155
gene id: 8128:LOC100695155
uniprot id: I3KFE2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:tmem192
gene id: 8128:tmem192
uniprot id: A0A669DA19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

8128:LOC100703740
gene id: 8128:LOC100703740
uniprot id: I3KR91
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8128:sez6l2
gene id: 8128:sez6l2
uniprot id: I3KCE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102078638
gene id: 8128:LOC102078638
uniprot id: I3JEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

8128:LOC100707314
gene id: 8128:LOC100707314
uniprot id: I3K5D2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100708797
gene id: 8128:LOC100708797
uniprot id: I3JHI1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8128:LOC100696847
gene id: 8128:LOC100696847
uniprot id: I3JVC2
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8128:LOC100692258
gene id: 8128:LOC100692258
uniprot id: A0A669CI66
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8128:arel1
gene id: 8128:arel1
uniprot id: A0A669DA01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:st6galnac5
gene id: 8128:st6galnac5
uniprot id: I3KPS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100699552
gene id: 8128:LOC100699552
uniprot id: I3IWT1
names: Similarity
messages: Belongs to the phospholipase D family.

8128:e2f3
gene id: 8128:e2f3
uniprot id: I3JJ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8128:gabra4
gene id: 8128:gabra4
uniprot id: I3KFH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC102075727
gene id: 8128:LOC102075727
uniprot id: A0A669CSB9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8128:ireb2
gene id: 8128:ireb2
uniprot id: I3K4W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

8128:LOC100699343
gene id: 8128:LOC100699343
uniprot id: I3JH20
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:mvp
gene id: 8128:mvp
uniprot id: A0A669CF57
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100707098
gene id: 8128:LOC100707098
uniprot id: A0A669EMF5
uniprot id: A0A669F1X0
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

8128:meis1
gene id: 8128:meis1
uniprot id: A0A669ENP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8128:LOC102077341
gene id: 8128:LOC102077341
uniprot id: A0A669CJ57
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8128:LOC100706916
gene id: 8128:LOC100706916
uniprot id: A0A669B1U5
names: Similarity
messages: Belongs to the CKAP2 family.

8128:fignl1
gene id: 8128:fignl1
uniprot id: I3KZM4
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:LOC109194170
gene id: 8128:LOC109194170
uniprot id: A0A669E6Y7
uniprot id: I3IY12
uniprot id: I3JUJ9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:pigg
gene id: 8128:pigg
uniprot id: I3KFG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:trhde
gene id: 8128:trhde
uniprot id: A0A669F9I6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100709732
gene id: 8128:LOC100709732
uniprot id: I3KWE6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:pde6d
gene id: 8128:pde6d
uniprot id: A0A669EGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: cilium basal body
messages: cytosol

8128:LOC100711622
gene id: 8128:LOC100711622
uniprot id: A0A669DZ07
uniprot id: I3JRT6
names: Similarity
messages: Belongs to the lipin family.

8128:LOC100704650
gene id: 8128:LOC100704650
uniprot id: A0A669DS93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100692975
gene id: 8128:LOC100692975
uniprot id: A0A669EPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Membrane

8128:ccnl1
gene id: 8128:ccnl1
uniprot id: A0A669B6M0
names: Similarity
names: Subunit
messages: Belongs to the cyclin family.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:LOC100711843
gene id: 8128:LOC100711843
uniprot id: I3K2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

8128:LOC100698479
gene id: 8128:LOC100698479
uniprot id: I3JCH7
names: Similarity
messages: Belongs to the multicopper oxidase family.

8128:tsnax
gene id: 8128:tsnax
uniprot id: I3JV36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

8128:LOC100701604
gene id: 8128:LOC100701604
uniprot id: I3KY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:brk1
gene id: 8128:brk1
uniprot id: A0A669DNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

8128:LOC100706476
gene id: 8128:LOC100706476
uniprot id: I3KR21
names: Subcellular Location Annotation
messages: Nucleus

8128:sgk2
gene id: 8128:sgk2
uniprot id: A0A669D525
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100708132
gene id: 8128:LOC100708132
uniprot id: A0A669D8D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

8128:ntmt1
gene id: 8128:ntmt1
uniprot id: A0A669CQB6
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

8128:sap18
gene id: 8128:sap18
uniprot id: I3K1N3
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

8128:suds3
gene id: 8128:suds3
uniprot id: A0A669EQV7
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC109194741
gene id: 8128:LOC109194741
uniprot id: A0A669EEW0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100692587
gene id: 8128:LOC100692587
uniprot id: I3J5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

8128:LOC100712163
gene id: 8128:LOC100712163
uniprot id: I3JUT4
names: Similarity
messages: Belongs to the cullin family.

8128:il6st
gene id: 8128:il6st
uniprot id: A0A6C0NFW6
uniprot id: I3K0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

8128:LOC100706636
gene id: 8128:LOC100706636
uniprot id: A0A669CMV2
names: Similarity
messages: Belongs to the neuritin family.

8128:LOC100703611
gene id: 8128:LOC100703611
uniprot id: I3J9I4
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8128:LOC102079697
gene id: 8128:LOC102079697
uniprot id: I3L050
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100708712
gene id: 8128:LOC100708712
uniprot id: A0A669B7A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

8128:LOC100696071
gene id: 8128:LOC100696071
uniprot id: I3KTF3
names: Similarity
messages: Belongs to the intermediate filament family.

8128:chst10
gene id: 8128:chst10
uniprot id: I3K2T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100690057
gene id: 8128:LOC100690057
uniprot id: A0A669AXA4
uniprot id: A0A669E426
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8128:LOC100692926
gene id: 8128:LOC100692926
uniprot id: A0A669DZZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:ctso
gene id: 8128:ctso
uniprot id: I3IXW1
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:ptgdsl2
gene id: 8128:ptgdsl2
uniprot id: I7I7M1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:med19
gene id: 8128:med19
uniprot id: A0A669EPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:klc1
gene id: 8128:klc1
uniprot id: A0A669DTP4
uniprot id: A0A669E4M0
uniprot id: I3K3G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8128:bloc1s6
gene id: 8128:bloc1s6
uniprot id: I3K6J9
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

8128:adck2
gene id: 8128:adck2
uniprot id: I3JQE0
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8128:gli3
gene id: 8128:gli3
uniprot id: I3JGE9
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8128:LOC100702538
gene id: 8128:LOC100702538
uniprot id: I3JN81
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8128:LOC100707278
gene id: 8128:LOC100707278
uniprot id: I3JU45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:xrn1
gene id: 8128:xrn1
uniprot id: A0A669BQH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm

8128:LOC100690178
gene id: 8128:LOC100690178
uniprot id: I3KN54
names: Similarity
messages: Belongs to the HARBI1 family.

8128:cryz
gene id: 8128:cryz
uniprot id: I3KIK2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8128:notch1
gene id: 8128:notch1
uniprot id: I3JX40
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

8128:kdelc2
gene id: 8128:kdelc2
uniprot id: I3JY89
names: Similarity
messages: Belongs to the KDELC family.

8128:kcmf1
gene id: 8128:kcmf1
uniprot id: I3JKZ8
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

8128:washc3
gene id: 8128:washc3
uniprot id: I3ITX6
names: Similarity
messages: Belongs to the CCDC53 family.

8128:ptprd
gene id: 8128:ptprd
uniprot id: A0A669F3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
messages: Membrane

8128:LOC100690457
gene id: 8128:LOC100690457
uniprot id: I3K9V5
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100706315
gene id: 8128:LOC100706315
uniprot id: A0A669D5B5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8128:higd2a
gene id: 8128:higd2a
uniprot id: A0A669CY11
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

8128:LOC100690066
gene id: 8128:LOC100690066
uniprot id: I3KM75
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Membrane

8128:tcf7
gene id: 8128:tcf7
uniprot id: A0A669CF41
uniprot id: A0A669DID9
uniprot id: I3KKX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8128:LOC100690570
gene id: 8128:LOC100690570
uniprot id: I3KHL7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8128:slc17a9
gene id: 8128:slc17a9
uniprot id: A0A669EAH3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100711061
gene id: 8128:LOC100711061
uniprot id: I3KIL6
names: Similarity
messages: Belongs to the RRM TRSPAP family.

8128:LOC100700830
gene id: 8128:LOC100700830
uniprot id: I3J983
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707404
gene id: 8128:LOC100707404
uniprot id: A0A669C9D7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100702785
gene id: 8128:LOC100702785
uniprot id: I3J7S2
names: Similarity
messages: Belongs to the FAM168 family.

8128:LOC100707781
gene id: 8128:LOC100707781
uniprot id: A0A669BY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8128:ergic3
gene id: 8128:ergic3
uniprot id: A0A669BN64
uniprot id: I3J9K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8128:LOC100697381
gene id: 8128:LOC100697381
uniprot id: A0A669D0Q3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100534493
gene id: 8128:LOC100534493
uniprot id: I3KSU1
names: Similarity
messages: Belongs to the TGF-beta family.

8128:gsx2
gene id: 8128:gsx2
uniprot id: I3J4J4
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100703334
gene id: 8128:LOC100703334
uniprot id: I3J793
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

8128:LOC100706107
gene id: 8128:LOC100706107
uniprot id: A0A669CDZ1
names: Similarity
messages: Belongs to the RRM elav family.

8128:LOC100534432
gene id: 8128:LOC100534432
uniprot id: Q8UVJ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100706668
gene id: 8128:LOC100706668
uniprot id: I3JE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:gnrh1
gene id: 8128:gnrh1
uniprot id: I3JYC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted

8128:LOC100709892
gene id: 8128:LOC100709892
uniprot id: A0A669CHX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8128:cfap298
gene id: 8128:cfap298
uniprot id: I3JAJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

8128:LOC100710729
gene id: 8128:LOC100710729
uniprot id: I3KG98
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

8128:LOC100689876
gene id: 8128:LOC100689876
uniprot id: I3KJK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:acot8
gene id: 8128:acot8
uniprot id: I3KWL7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:zranb2
gene id: 8128:zranb2
uniprot id: I3J393
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: May interfere with constitutive 5'-splice site selection.
messages: Nucleus

8128:tnfaip3
gene id: 8128:tnfaip3
uniprot id: I3IWW3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100702456
gene id: 8128:LOC100702456
uniprot id: I3K7T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

8128:hras
gene id: 8128:hras
uniprot id: A0A669CHP8
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:LOC100698659
gene id: 8128:LOC100698659
uniprot id: A0A669B066
uniprot id: A0A669CTN7
uniprot id: A0A669F2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8128:LOC100690049
gene id: 8128:LOC100690049
uniprot id: A0A669DHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:kin
gene id: 8128:kin
uniprot id: A0A669CBY6
names: Similarity
messages: Belongs to the KIN17 family.

8128:mrrf
gene id: 8128:mrrf
uniprot id: I3J745
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

8128:slain2
gene id: 8128:slain2
uniprot id: A0A669BJ66
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

8128:LOC106097837
gene id: 8128:LOC106097837
uniprot id: A0A669DCZ7
names: Similarity
messages: Belongs to the cystatin family.

8128:dapk3
gene id: 8128:dapk3
uniprot id: I3KQN8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:nefm
gene id: 8128:nefm
uniprot id: I3J829
names: Similarity
messages: Belongs to the intermediate filament family.

8128:LOC100703237
gene id: 8128:LOC100703237
uniprot id: I3J101
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100695146
gene id: 8128:LOC100695146
uniprot id: A0A669B232
uniprot id: A0A669BFU0
uniprot id: I3JYG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:LOC100706013
gene id: 8128:LOC100706013
uniprot id: I3J3L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium

8128:LOC100696775
gene id: 8128:LOC100696775
uniprot id: A0A669DX72
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8128:tsen34
gene id: 8128:tsen34
uniprot id: I3KKW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

8128:rpgrip1l
gene id: 8128:rpgrip1l
uniprot id: I3KPB9
names: Similarity
messages: Belongs to the RPGRIP1 family.

8128:grb14
gene id: 8128:grb14
uniprot id: A0A669D4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

8128:dio3
gene id: 8128:dio3
uniprot id: Q9I966
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

8128:LOC100704523
gene id: 8128:LOC100704523
uniprot id: A0A669BIU9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

8128:lg12h9orf64
gene id: 8128:lg12h9orf64
uniprot id: I3KCQ0
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

8128:LOC100691229
gene id: 8128:LOC100691229
uniprot id: A0A669C0N4
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

8128:LOC100692180
gene id: 8128:LOC100692180
uniprot id: A0A669B2K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8128:LOC100693960
gene id: 8128:LOC100693960
uniprot id: I3J153
names: Similarity
messages: Belongs to the beta-catenin family.

8128:LOC100704880
gene id: 8128:LOC100704880
uniprot id: I3KQZ7
names: Similarity
messages: Belongs to the CNKSR family.

8128:LOC100702252
gene id: 8128:LOC100702252
uniprot id: I3JU23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

8128:LOC102079346
gene id: 8128:LOC102079346
uniprot id: I3JSN8
names: Subcellular Location Annotation
messages: Membrane

8128:naprt
gene id: 8128:naprt
uniprot id: I3KTS7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

8128:zdhhc23
gene id: 8128:zdhhc23
uniprot id: A0A669D381
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC106098551
gene id: 8128:LOC106098551
uniprot id: I3KGT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

8128:tmem53
gene id: 8128:tmem53
uniprot id: I3JR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

8128:LOC100705677
gene id: 8128:LOC100705677
uniprot id: I3KXH9
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100699909
gene id: 8128:LOC100699909
uniprot id: I3J0R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

8128:LOC100703294
gene id: 8128:LOC100703294
uniprot id: I3JJD0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100708400
gene id: 8128:LOC100708400
uniprot id: A0A669EHY0
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8128:igf1
gene id: 8128:igf1
uniprot id: B0Z6G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8128:LOC100697801
gene id: 8128:LOC100697801
uniprot id: A0A669DWQ6
uniprot id: I3JYN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8128:LOC100693707
gene id: 8128:LOC100693707
uniprot id: I3JRK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:psmd1
gene id: 8128:psmd1
uniprot id: I3J315
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

8128:LOC100690587
gene id: 8128:LOC100690587
uniprot id: I3KPP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:eif4a2
gene id: 8128:eif4a2
uniprot id: A0A669E086
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8128:ung
gene id: 8128:ung
uniprot id: I3K703
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

8128:LOC100697129
gene id: 8128:LOC100697129
uniprot id: I3KT69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100702705
gene id: 8128:LOC100702705
uniprot id: I3JSZ3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:pdrg1
gene id: 8128:pdrg1
uniprot id: A0A669CYQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

8128:dhrs1
gene id: 8128:dhrs1
uniprot id: I3KEM1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC109194552
gene id: 8128:LOC109194552
uniprot id: A0A669DR22
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693211
gene id: 8128:LOC100693211
uniprot id: A0A669E5V0
uniprot id: I3JUF2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:ppm1g
gene id: 8128:ppm1g
uniprot id: I3KK61
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100710305
gene id: 8128:LOC100710305
uniprot id: A0A669E8U6
names: Similarity
messages: Belongs to the BZW family.

8128:grb2
gene id: 8128:grb2
uniprot id: A0A669EQK9
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

8128:LOC100703700
gene id: 8128:LOC100703700
uniprot id: A0A669B5M8
uniprot id: I3IXH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

8128:retreg3
gene id: 8128:retreg3
uniprot id: A0A669B8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100703423
gene id: 8128:LOC100703423
uniprot id: A0A669EGE5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

8128:cpsf2
gene id: 8128:cpsf2
uniprot id: I3JEY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

8128:mc1r
gene id: 8128:mc1r
uniprot id: I3KZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

8128:LOC109196592
gene id: 8128:LOC109196592
uniprot id: A0A669CDX5
names: Subcellular Location Annotation
messages: Nucleus

8128:prss56
gene id: 8128:prss56
uniprot id: I3JUX8
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100693391
gene id: 8128:LOC100693391
uniprot id: I3IUS7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:LOC102082918
gene id: 8128:LOC102082918
uniprot id: I3KZE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100694167
gene id: 8128:LOC100694167
uniprot id: A0A669C239
names: Similarity
messages: Belongs to the epsin family.

8128:gsta
gene id: 8128:gsta
uniprot id: A8WE65
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

8128:slc37a4
gene id: 8128:slc37a4
uniprot id: I3JD84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8128:snx33
gene id: 8128:snx33
uniprot id: I3K4Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8128:LOC100701072
gene id: 8128:LOC100701072
uniprot id: A0A669BTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:tbcd
gene id: 8128:tbcd
uniprot id: A0A669D7U5
names: Similarity
messages: Belongs to the TBCD family.

8128:LOC100702982
gene id: 8128:LOC100702982
uniprot id: A0A669DHH6
uniprot id: A0A669E115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8128:mmp19
gene id: 8128:mmp19
uniprot id: I3KSS1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8128:f13a1
gene id: 8128:f13a1
uniprot id: I3K6U6
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

8128:LOC100705665
gene id: 8128:LOC100705665
uniprot id: I3KH77
names: Subcellular Location Annotation
messages: sarcolemma

8128:slc30a1
gene id: 8128:slc30a1
uniprot id: A0A669D7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8128:LOC100693698
gene id: 8128:LOC100693698
uniprot id: A0A669DUB6
uniprot id: A0A669EP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cytoplasm

8128:dph6
gene id: 8128:dph6
uniprot id: A0A669DL31
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

8128:LOC100702606
gene id: 8128:LOC100702606
uniprot id: I3KCC2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100701022
gene id: 8128:LOC100701022
uniprot id: I3JZ01
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

8128:LOC100694100
gene id: 8128:LOC100694100
uniprot id: I3K602
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: extracellular space

8128:LOC100710995
gene id: 8128:LOC100710995
uniprot id: I3KIX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8128:osbpl10
gene id: 8128:osbpl10
uniprot id: A0A669E7M4
names: Similarity
messages: Belongs to the OSBP family.

8128:LOC100694875
gene id: 8128:LOC100694875
uniprot id: I3IXY2
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8128:LOC109201894
gene id: 8128:LOC109201894
uniprot id: A0A669DFV1
names: Similarity
messages: Belongs to the globin family.

8128:LOC100692541
gene id: 8128:LOC100692541
uniprot id: I3KGP4
names: Subcellular Location Annotation
messages: Membrane

8128:rars2
gene id: 8128:rars2
uniprot id: I3JET9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8128:LOC100698940
gene id: 8128:LOC100698940
uniprot id: I3JPZ5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100712468
gene id: 8128:LOC100712468
uniprot id: I3JP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:LOC100708917
gene id: 8128:LOC100708917
uniprot id: I3JL38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8128:gnptab
gene id: 8128:gnptab
uniprot id: A0A669DCA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

8128:LOC100690686
gene id: 8128:LOC100690686
uniprot id: A0A669BGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8128:LOC100692669
gene id: 8128:LOC100692669
uniprot id: A0A669EJ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:fgf19
gene id: 8128:fgf19
uniprot id: I3KNV1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:ptdss2
gene id: 8128:ptdss2
uniprot id: I3JQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:allc
gene id: 8128:allc
uniprot id: A0A669BKV5
names: Similarity
messages: Belongs to the allantoicase family.

8128:lyrm2
gene id: 8128:lyrm2
uniprot id: A0A669DSJ5
names: Similarity
messages: Belongs to the complex I LYR family.

8128:LOC100694697
gene id: 8128:LOC100694697
uniprot id: I3KNW4
names: Similarity
messages: Belongs to the formin homology family.

8128:clpp
gene id: 8128:clpp
uniprot id: I3JG90
names: Similarity
messages: Belongs to the peptidase S14 family.

8128:LOC100702146
gene id: 8128:LOC100702146
uniprot id: A0A669FBI9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:LOC100707048
gene id: 8128:LOC100707048
uniprot id: A0A669BN11
uniprot id: A0A669ERZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8128:LOC100699176
gene id: 8128:LOC100699176
uniprot id: I3JVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:gata4
gene id: 8128:gata4
uniprot id: A8DS45
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102075670
gene id: 8128:LOC102075670
uniprot id: I3KMM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Vesicle
messages: dendrite

8128:LOC100704044
gene id: 8128:LOC100704044
uniprot id: I3KZP7
names: Subcellular Location Annotation
messages: Membrane

8128:gpr54
gene id: 8128:gpr54
uniprot id: Q6BD04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Expressed in a significantly high percentage (45-60%) of mature GnRH1, GnRH2, and GnRH3 neurons and in immature GnRH3 neurons, which had migrated to the vicinity of their final locations in the brain. Only 5% of immature GnRH1 and GnRH2 neurons have receptor transcripts.
messages: Receptor speculated to be essential for sexual development. May regulate gonadotropin-releasing hormone (GnRH) secretion. The receptor expression could be a 'stop signal' for GnRH1, GnRH2, and GnRH3 neuronal migration, leading to suppression of cell growth and modulation of GnRH secretion, which is important for normal sexual development.

8128:rora
gene id: 8128:rora
uniprot id: A0A669EG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:stxbp3
gene id: 8128:stxbp3
uniprot id: I3JNS7
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8128:LOC100692842
gene id: 8128:LOC100692842
uniprot id: I3JTC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100708212
gene id: 8128:LOC100708212
uniprot id: A0A669DC75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

8128:wnt7b
gene id: 8128:wnt7b
uniprot id: I3JQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:snx30
gene id: 8128:snx30
uniprot id: A0A669EZ59
names: Similarity
messages: Belongs to the sorting nexin family.

8128:sncg
gene id: 8128:sncg
uniprot id: A0A669D7L8
uniprot id: I3JIZ8
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

8128:LOC100711382
gene id: 8128:LOC100711382
uniprot id: I3JEU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8128:psme3
gene id: 8128:psme3
uniprot id: I3KPF7
names: Similarity
messages: Belongs to the PA28 family.

8128:LOC100696541
gene id: 8128:LOC100696541
uniprot id: A0A669CGU3
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8128:LOC100699839
gene id: 8128:LOC100699839
uniprot id: I3IVU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8128:LOC100695248
gene id: 8128:LOC100695248
uniprot id: I3JIE9
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100704294
gene id: 8128:LOC100704294
uniprot id: A0A669F4Z6
uniprot id: I3JLA7
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8128:LOC109194326
gene id: 8128:LOC109194326
uniprot id: I3JTM0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:slc4a4
gene id: 8128:slc4a4
uniprot id: A0A669CB88
uniprot id: I3K9G9
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

8128:lyrm7
gene id: 8128:lyrm7
uniprot id: A0A669CFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
messages: Belongs to the complex I LYR family.
messages: Interacts with UQCRFS1.
messages: Mitochondrion matrix

8128:LOC100696835
gene id: 8128:LOC100696835
uniprot id: I3K0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

8128:kmt2b
gene id: 8128:kmt2b
uniprot id: I3J3L0
names: Subcellular Location Annotation
messages: Nucleus

8128:aga
gene id: 8128:aga
uniprot id: I3IXZ2
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8128:LOC100699797
gene id: 8128:LOC100699797
uniprot id: I3KUJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8128:pdp1
gene id: 8128:pdp1
uniprot id: A0A669DX10
names: Similarity
messages: Belongs to the PP2C family.

8128:enpep
gene id: 8128:enpep
uniprot id: A0A669B7C2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100711421
gene id: 8128:LOC100711421
uniprot id: A0A669EI70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

8128:itm2b
gene id: 8128:itm2b
uniprot id: I3KGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8128:LOC100704482
gene id: 8128:LOC100704482
uniprot id: A0A669BAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8128:LOC100689988
gene id: 8128:LOC100689988
uniprot id: I3JJQ8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:cpne8
gene id: 8128:cpne8
uniprot id: I3JU05
names: Similarity
messages: Belongs to the copine family.

8128:LOC102076859
gene id: 8128:LOC102076859
uniprot id: I3KWW4
names: Similarity
messages: Belongs to the dysbindin family.

8128:pias4
gene id: 8128:pias4
uniprot id: A0A669DLT0
names: Similarity
messages: Belongs to the PIAS family.

8128:bglap
gene id: 8128:bglap
uniprot id: A0A669EWS3
names: Function
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein (By similarity). The carboxylated form binds strongly to apatite and calcium.

8128:LOC100694799
gene id: 8128:LOC100694799
uniprot id: I3KQT8
uniprot id: I3KQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:casc3
gene id: 8128:casc3
uniprot id: I3JS90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

8128:ciao2a
gene id: 8128:ciao2a
uniprot id: A0A669C5K1
names: Similarity
messages: Belongs to the MIP18 family.

8128:isca2
gene id: 8128:isca2
uniprot id: A0A669DXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

8128:LOC100700731
gene id: 8128:LOC100700731
uniprot id: I3K9D4
names: Similarity
messages: Belongs to the peptidase M67C family.

8128:atg4c
gene id: 8128:atg4c
uniprot id: I3JQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8128:LOC100698144
gene id: 8128:LOC100698144
uniprot id: A0A669D433
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100712318
gene id: 8128:LOC100712318
uniprot id: I3IZ94
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100700421
gene id: 8128:LOC100700421
uniprot id: I3JZH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:slc44a5
gene id: 8128:slc44a5
uniprot id: A0A669C290
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8128:LOC100707941
gene id: 8128:LOC100707941
uniprot id: A0A669EQ29
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100692806
gene id: 8128:LOC100692806
uniprot id: I3K3C1
names: Similarity
messages: Belongs to the SEC6 family.

8128:sgcz
gene id: 8128:sgcz
uniprot id: A0A669BD41
uniprot id: I3KGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

8128:sugct
gene id: 8128:sugct
uniprot id: A0A669F4S0
names: Similarity
messages: Belongs to the CoA-transferase III family.

8128:ddx52
gene id: 8128:ddx52
uniprot id: A0A669EAM6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8128:LOC100703707
gene id: 8128:LOC100703707
uniprot id: A0A669BGA2
names: Similarity
messages: Belongs to the FBPase class 1 family.

8128:LOC100705607
gene id: 8128:LOC100705607
uniprot id: A0A669C4H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:alg9
gene id: 8128:alg9
uniprot id: A0A669D1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC102077549
gene id: 8128:LOC102077549
uniprot id: A0A669ER70
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

8128:bysl
gene id: 8128:bysl
uniprot id: I3KRU6
names: Similarity
messages: Belongs to the bystin family.

8128:glyctk
gene id: 8128:glyctk
uniprot id: I3J7Z1
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

8128:LOC100701748
gene id: 8128:LOC100701748
uniprot id: A0A669CUB5
uniprot id: I3J0F2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100698302
gene id: 8128:LOC100698302
uniprot id: I3IX29
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8128:tamm41
gene id: 8128:tamm41
uniprot id: I3KA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

8128:LOC100699198
gene id: 8128:LOC100699198
uniprot id: I3JP04
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
messages: Nucleus
messages: Transcription factor.

8128:LOC102077988
gene id: 8128:LOC102077988
uniprot id: I3JAC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

8128:LOC100694234
gene id: 8128:LOC100694234
uniprot id: A0A669DUE1
names: Similarity
messages: Belongs to the NDRG family.

8128:LOC100694434
gene id: 8128:LOC100694434
uniprot id: A0A669DZJ2
names: Subcellular Location Annotation
messages: Nucleus

8128:dmap1
gene id: 8128:dmap1
uniprot id: I3J010
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100708122
gene id: 8128:LOC100708122
uniprot id: I3KIB1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:mecp2
gene id: 8128:mecp2
uniprot id: A0A669B400
names: Subcellular Location Annotation
messages: Nucleus

8128:naa40
gene id: 8128:naa40
uniprot id: A0A669CS03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

8128:vapa
gene id: 8128:vapa
uniprot id: I3KQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100702638
gene id: 8128:LOC100702638
uniprot id: I3JL07
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:celf4
gene id: 8128:celf4
uniprot id: A0A669B749
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

8128:LOC100703515
gene id: 8128:LOC100703515
uniprot id: A0A669CBG1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8128:msl3
gene id: 8128:msl3
uniprot id: I3K291
names: Subcellular Location Annotation
messages: Nucleus

8128:popdc2
gene id: 8128:popdc2
uniprot id: A0A669F723
names: Similarity
messages: Belongs to the popeye family.

8128:LOC100696252
gene id: 8128:LOC100696252
uniprot id: I3JBQ2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696727
gene id: 8128:LOC100696727
uniprot id: I3KY78
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100694538
gene id: 8128:LOC100694538
uniprot id: I3K8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8128:pus3
gene id: 8128:pus3
uniprot id: I3KH33
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8128:trappc3
gene id: 8128:trappc3
uniprot id: A0A669DR85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

8128:chmp4b
gene id: 8128:chmp4b
uniprot id: I3J0N1
names: Similarity
messages: Belongs to the SNF7 family.

8128:tlcd1
gene id: 8128:tlcd1
uniprot id: I3K622
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696389
gene id: 8128:LOC100696389
uniprot id: I3JSW2
names: Similarity
messages: Belongs to the CRK family.

8128:LOC100692811
gene id: 8128:LOC100692811
uniprot id: A0A669BQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:arrdc2
gene id: 8128:arrdc2
uniprot id: A0A669CVI0
uniprot id: I3K4J5
names: Similarity
messages: Belongs to the arrestin family.

8128:LOC100710181
gene id: 8128:LOC100710181
uniprot id: I3JLS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

8128:plat
gene id: 8128:plat
uniprot id: I3KAA9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:LOC100707936
gene id: 8128:LOC100707936
uniprot id: I3KQG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8128:LOC109203810
gene id: 8128:LOC109203810
uniprot id: A0A669DKM4
names: Subcellular Location Annotation
messages: Membrane

8128:gpat4
gene id: 8128:gpat4
uniprot id: I3K0L0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:LOC102082339
gene id: 8128:LOC102082339
uniprot id: I3KR24
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100704579
gene id: 8128:LOC100704579
uniprot id: I3KUV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:bckdk
gene id: 8128:bckdk
uniprot id: A0A669ESE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8128:LOC100702951
gene id: 8128:LOC100702951
uniprot id: I3JNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8128:LOC109201538
gene id: 8128:LOC109201538
uniprot id: A0A669BAT8
names: Subcellular Location Annotation
messages: extracellular space

8128:lztfl1
gene id: 8128:lztfl1
uniprot id: I3JGE4
uniprot id: I3JGE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

8128:LOC100710292
gene id: 8128:LOC100710292
uniprot id: A0A669BPW0
uniprot id: A0A669ED75
uniprot id: I3K0E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8128:LOC100709126
gene id: 8128:LOC100709126
uniprot id: A0A669CMH8
names: Similarity
messages: Belongs to the dysbindin family.

8128:LOC100695486
gene id: 8128:LOC100695486
uniprot id: I3KXK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100708495
gene id: 8128:LOC100708495
uniprot id: A0A669EWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100699650
gene id: 8128:LOC100699650
uniprot id: A0A669D0R9
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:LOC100696598
gene id: 8128:LOC100696598
uniprot id: I3JTJ7
names: Subcellular Location Annotation
messages: Nucleus

8128:ttc3
gene id: 8128:ttc3
uniprot id: I3KL76
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100700425
gene id: 8128:LOC100700425
uniprot id: I3JWP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

8128:srd5a1
gene id: 8128:srd5a1
uniprot id: A0A669EP75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

8128:LOC100707779
gene id: 8128:LOC100707779
uniprot id: A0A669B945
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8128:mms22l
gene id: 8128:mms22l
uniprot id: I3IU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

8128:sema3d
gene id: 8128:sema3d
uniprot id: I3KCL1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100692088
gene id: 8128:LOC100692088
uniprot id: A0A669BNQ7
uniprot id: A0A669BU08
uniprot id: A0A669CL05
uniprot id: A0A669EC88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

8128:igf2
gene id: 8128:igf2
uniprot id: B0Z6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8128:evc2
gene id: 8128:evc2
uniprot id: A0A669EKE7
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

8128:msrb2
gene id: 8128:msrb2
uniprot id: I3KAM6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

8128:LOC100708574
gene id: 8128:LOC100708574
uniprot id: I3JBU6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100690534
gene id: 8128:LOC100690534
uniprot id: A0A669BYS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:irf4
gene id: 8128:irf4
uniprot id: I3JTB2
names: Subcellular Location Annotation
messages: Nucleus

8128:rev3l
gene id: 8128:rev3l
uniprot id: A0A669E491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

8128:LOC100700962
gene id: 8128:LOC100700962
uniprot id: A0A669D0A1
names: Similarity
messages: Belongs to the cornifelin family.

8128:LOC100702556
gene id: 8128:LOC100702556
uniprot id: I3JGA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:mrpl43
gene id: 8128:mrpl43
uniprot id: A0A669B7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

8128:tspan13
gene id: 8128:tspan13
uniprot id: I3KG25
names: Subcellular Location Annotation
messages: Membrane

8128:chpf2
gene id: 8128:chpf2
uniprot id: I3JG24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8128:LOC100708842
gene id: 8128:LOC100708842
uniprot id: I3J3G4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC106097693
gene id: 8128:LOC106097693
uniprot id: I3JGV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

8128:top3a
gene id: 8128:top3a
uniprot id: I3JP29
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

8128:LOC100709289
gene id: 8128:LOC100709289
uniprot id: A0A669D6Y9
uniprot id: I3KVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:LOC100706618
gene id: 8128:LOC100706618
uniprot id: A0A669DI77
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8128:sema3c
gene id: 8128:sema3c
uniprot id: A0A669DAD8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100696176
gene id: 8128:LOC100696176
uniprot id: A0A669EVU9
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

8128:hepacam2
gene id: 8128:hepacam2
uniprot id: I3JXM9
names: Subcellular Location Annotation
messages: Membrane

8128:lg15h19orf24
gene id: 8128:lg15h19orf24
uniprot id: A0A669DGW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

8128:LOC100709793
gene id: 8128:LOC100709793
uniprot id: I3KFR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Golgi apparatus membrane
messages: Sialate:O-sulfotransferase which catalyzes 8-O-sulfation at the Sia-glycan level using 3'-phosphoadenosine 5'-phosphosulfate (PAPS) as a donor, forming 8-O-sulfated Sia (Sia8S)-glycans.

8128:LOC100700947
gene id: 8128:LOC100700947
uniprot id: I3K0Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:hikeshi
gene id: 8128:hikeshi
uniprot id: I3KYD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

8128:tyms
gene id: 8128:tyms
uniprot id: I3JFM1
names: Similarity
messages: Belongs to the thymidylate synthase family.

8128:xpc
gene id: 8128:xpc
uniprot id: I3IZS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

8128:LOC106096620
gene id: 8128:LOC106096620
uniprot id: A0A669D5A5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100711236
gene id: 8128:LOC100711236
uniprot id: A0A669B1V0
uniprot id: A0A669CRE3
uniprot id: A0A669DQR9
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8128:LOC102080697
gene id: 8128:LOC102080697
uniprot id: A0A669BM79
uniprot id: A0A669D7Y6
names: Similarity
messages: Belongs to the SH3RF family.

8128:LOC100707466
gene id: 8128:LOC100707466
uniprot id: A0A669EC39
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8128:ldlrad3
gene id: 8128:ldlrad3
uniprot id: A0A669CTF2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100707618
gene id: 8128:LOC100707618
uniprot id: A0A669BRY0
names: Subcellular Location Annotation
messages: Membrane

8128:lg18h1orf123
gene id: 8128:lg18h1orf123
uniprot id: A0A669CC61
names: Similarity
messages: Belongs to the UPF0587 family.

8128:syt14
gene id: 8128:syt14
uniprot id: I3JNF4
names: Similarity
messages: Belongs to the synaptotagmin family.

8128:wnk2
gene id: 8128:wnk2
uniprot id: I3KKQ5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8128:LOC100709939
gene id: 8128:LOC100709939
uniprot id: I3KIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:LOC100694372
gene id: 8128:LOC100694372
uniprot id: I3K604
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion

8128:LOC100695572
gene id: 8128:LOC100695572
uniprot id: A0A669E8E1
names: Similarity
messages: Belongs to the SNF7 family.

8128:LOC102077503
gene id: 8128:LOC102077503
uniprot id: A0A669CB24
uniprot id: I3JUN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8128:LOC100706644
gene id: 8128:LOC100706644
uniprot id: A0A669BFR2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100702550
gene id: 8128:LOC100702550
uniprot id: A0A669B5E9
names: Similarity
messages: Belongs to the yippee family.

8128:LOC100708375
gene id: 8128:LOC100708375
uniprot id: A0A669CMP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8128:LOC100696613
gene id: 8128:LOC100696613
uniprot id: I3J6G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8128:polr2b
gene id: 8128:polr2b
uniprot id: I3ITZ5
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

8128:LOC100707813
gene id: 8128:LOC100707813
uniprot id: I3JHD0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8128:LOC100710341
gene id: 8128:LOC100710341
uniprot id: I3J6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8128:LOC100703097
gene id: 8128:LOC100703097
uniprot id: A0A669D5R7
uniprot id: A0A669DLK4
uniprot id: I3K0P3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

8128:fam72a
gene id: 8128:fam72a
uniprot id: I3KT40
names: Similarity
messages: Belongs to the FAM72 family.

8128:cmtr1
gene id: 8128:cmtr1
uniprot id: A0A669BBN8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

8128:cdk5
gene id: 8128:cdk5
uniprot id: I3JSU3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100693895
gene id: 8128:LOC100693895
uniprot id: A0A669ENN9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100710753
gene id: 8128:LOC100710753
uniprot id: A0A669EP07
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:LOC100694707
gene id: 8128:LOC100694707
uniprot id: A0A669E9Y1
uniprot id: I3JAG2
names: Subcellular Location Annotation
messages: extracellular space

8128:lap3
gene id: 8128:lap3
uniprot id: A0A669DWV8
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

8128:LOC100709643
gene id: 8128:LOC100709643
uniprot id: I3JLQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8128:LOC100703239
gene id: 8128:LOC100703239
uniprot id: A0A669BZL7
names: Similarity
messages: Belongs to the asteroid family.

8128:notum
gene id: 8128:notum
uniprot id: A0A669BXV3
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

8128:LOC100708033
gene id: 8128:LOC100708033
uniprot id: I3JBT2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100700436
gene id: 8128:LOC100700436
uniprot id: I3JG10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

8128:LOC100702230
gene id: 8128:LOC100702230
uniprot id: A0A669D326
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:psmb3
gene id: 8128:psmb3
uniprot id: I3J5E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8128:dot1l
gene id: 8128:dot1l
uniprot id: A0A669BJT4
uniprot id: A0A669BMB3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: In contrast to other lysine histone methyltransferases, it does not contain a SET domain, suggesting the existence of another mechanism for methylation of lysine residues of histones.
messages: Nucleus

8128:dnajc22
gene id: 8128:dnajc22
uniprot id: A0A669ERY5
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

8128:LOC100704829
gene id: 8128:LOC100704829
uniprot id: A0A669D3P8
uniprot id: A0A669DN55
uniprot id: A0A669F4A1
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:pif1
gene id: 8128:pif1
uniprot id: I3JWJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

8128:atp6v1h
gene id: 8128:atp6v1h
uniprot id: A0A669BMJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8128:masp2
gene id: 8128:masp2
uniprot id: I3J215
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:med26
gene id: 8128:med26
uniprot id: I3K481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

8128:taf13
gene id: 8128:taf13
uniprot id: I3KYR5
names: Subcellular Location Annotation
messages: Nucleus

8128:tfdp1
gene id: 8128:tfdp1
uniprot id: I3K9P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8128:ppip5k1
gene id: 8128:ppip5k1
uniprot id: A0A669B0V4
uniprot id: A0A669CC44
uniprot id: A0A669DA61
uniprot id: A0A669DFI7
uniprot id: A0A669F8C9
uniprot id: I3JJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

8128:LOC100690808
gene id: 8128:LOC100690808
uniprot id: A0A669BBQ6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:rpl27
gene id: 8128:rpl27
uniprot id: I3JTN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

8128:LOC100700901
gene id: 8128:LOC100700901
uniprot id: I3KK06
names: Subcellular Location Annotation
messages: extracellular space

8128:hnrnph1
gene id: 8128:hnrnph1
uniprot id: I3KMN9
names: Subcellular Location Annotation
messages: nucleoplasm

8128:hoxd11
gene id: 8128:hoxd11
uniprot id: A0A669CA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:klhl21
gene id: 8128:klhl21
uniprot id: A0A669DHF2
names: Subcellular Location Annotation
messages: spindle

8128:LOC100700177
gene id: 8128:LOC100700177
uniprot id: I3IXG1
names: Subcellular Location Annotation
messages: sarcolemma

8128:rab39b
gene id: 8128:rab39b
uniprot id: I3JIX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8128:amacr
gene id: 8128:amacr
uniprot id: I3JL51
names: Similarity
messages: Belongs to the CoA-transferase III family.

8128:LOC100696143
gene id: 8128:LOC100696143
uniprot id: A0A669DVQ9
uniprot id: I3J4B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

8128:LOC100694446
gene id: 8128:LOC100694446
uniprot id: I3KE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

8128:smc5
gene id: 8128:smc5
uniprot id: I3K1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

8128:LOC100709700
gene id: 8128:LOC100709700
uniprot id: I3J4S8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100694992
gene id: 8128:LOC100694992
uniprot id: A0A669B6I9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8128:atxn10
gene id: 8128:atxn10
uniprot id: I3KIV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
messages: perinuclear region

8128:LOC100690876
gene id: 8128:LOC100690876
uniprot id: A0A669EIT2
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:fam214a
gene id: 8128:fam214a
uniprot id: A0A669BA13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

8128:lhx9
gene id: 8128:lhx9
uniprot id: I3K9H4
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100701705
gene id: 8128:LOC100701705
uniprot id: I3K025
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

8128:LOC109199604
gene id: 8128:LOC109199604
uniprot id: A0A669EP23
names: Subcellular Location Annotation
messages: Membrane

8128:myo1c
gene id: 8128:myo1c
uniprot id: I3JXQ0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:otx1
gene id: 8128:otx1
uniprot id: I3JXW4
names: Subcellular Location Annotation
messages: Nucleus

8128:nfasc
gene id: 8128:nfasc
uniprot id: A0A669ETK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

8128:nhej1
gene id: 8128:nhej1
uniprot id: I3K2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

8128:LOC100706512
gene id: 8128:LOC100706512
uniprot id: A0A669D5W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:fut7
gene id: 8128:fut7
uniprot id: I3KX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8128:LOC100699836
gene id: 8128:LOC100699836
uniprot id: I3JAP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8128:dio1
gene id: 8128:dio1
uniprot id: O42449
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iodothyronine deiodinase family.
messages: Endoplasmic reticulum membrane
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine).

8128:LOC100708164
gene id: 8128:LOC100708164
uniprot id: I3JEH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

8128:ddx1
gene id: 8128:ddx1
uniprot id: I3IVL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

8128:mrpl44
gene id: 8128:mrpl44
uniprot id: I3JDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

8128:fat1
gene id: 8128:fat1
uniprot id: A0A669DSQ2
uniprot id: I3JV89
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:tgs1
gene id: 8128:tgs1
uniprot id: I3JGK0
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

8128:cfap36
gene id: 8128:cfap36
uniprot id: I3IX84
uniprot id: I3IX85
names: Similarity
messages: Belongs to the CFAP36 family.

8128:LOC100696748
gene id: 8128:LOC100696748
uniprot id: A0A669D2M6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:sucnr1
gene id: 8128:sucnr1
uniprot id: I3J6K6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:nf2
gene id: 8128:nf2
uniprot id: I3JWV9
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8128:smad7
gene id: 8128:smad7
uniprot id: I3JLL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100692598
gene id: 8128:LOC100692598
uniprot id: I3K1C7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100694845
gene id: 8128:LOC100694845
uniprot id: I3KBY6
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100705727
gene id: 8128:LOC100705727
uniprot id: A0A669D684
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:clcn5
gene id: 8128:clcn5
uniprot id: A0A669BLH8
uniprot id: A0A669EXX0
uniprot id: I3JIN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:cln5
gene id: 8128:cln5
uniprot id: I3JI21
names: Similarity
messages: Belongs to the CLN5 family.

8128:adra1b
gene id: 8128:adra1b
uniprot id: A0A669CJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

8128:hsd17b3
gene id: 8128:hsd17b3
uniprot id: I3KD67
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100694365
gene id: 8128:LOC100694365
uniprot id: A0A669B0P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8128:piwil2
gene id: 8128:piwil2
uniprot id: I3JYQ7
names: Similarity
messages: Belongs to the argonaute family.

8128:cfap300
gene id: 8128:cfap300
uniprot id: I3J292
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

8128:polg
gene id: 8128:polg
uniprot id: A0A669D6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-A family.
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

8128:mpdu1
gene id: 8128:mpdu1
uniprot id: I3IVW7
names: Subcellular Location Annotation
messages: Membrane

8128:colgalt1
gene id: 8128:colgalt1
uniprot id: I3J0H9
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8128:park7
gene id: 8128:park7
uniprot id: A0A669CR78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

8128:LOC100695822
gene id: 8128:LOC100695822
uniprot id: I3IYT6
names: Similarity
messages: Belongs to the centrin family.

8128:gstz1
gene id: 8128:gstz1
uniprot id: A0A669DZR8
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

8128:LOC100707430
gene id: 8128:LOC100707430
uniprot id: A0A669BSX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

8128:sf3b3
gene id: 8128:sf3b3
uniprot id: I3JYZ8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100689957
gene id: 8128:LOC100689957
uniprot id: A0A669DDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

8128:kpna4
gene id: 8128:kpna4
uniprot id: I3J6S5
names: Similarity
messages: Belongs to the importin alpha family.

8128:LOC100694211
gene id: 8128:LOC100694211
uniprot id: I3JZ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8128:tmem178a
gene id: 8128:tmem178a
uniprot id: I3KV19
names: Similarity
messages: Belongs to the TMEM178 family.

8128:tmem167b
gene id: 8128:tmem167b
uniprot id: A0A669BE92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100702570
gene id: 8128:LOC100702570
uniprot id: I3KN98
names: Similarity
messages: Belongs to the DNase I family.

8128:LOC100709837
gene id: 8128:LOC100709837
uniprot id: I3K0D9
names: Similarity
messages: Belongs to the RUNDC3 family.

8128:dcp2
gene id: 8128:dcp2
uniprot id: A0A669BXG0
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

8128:LOC100690967
gene id: 8128:LOC100690967
uniprot id: A0A669B0E0
names: Similarity
messages: Belongs to the dynein intermediate chain family.

8128:slc8a3
gene id: 8128:slc8a3
uniprot id: A0A669EY91
uniprot id: I3KU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8128:slc25a36
gene id: 8128:slc25a36
uniprot id: I3KBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100693561
gene id: 8128:LOC100693561
uniprot id: I3KJM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100711310
gene id: 8128:LOC100711310
uniprot id: I3KHI2
names: Subcellular Location Annotation
messages: Membrane

8128:nr1h3
gene id: 8128:nr1h3
uniprot id: I3JEQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:LOC100695615
gene id: 8128:LOC100695615
uniprot id: I3J4A2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
messages: Nucleus
messages: Transcription factor.

8128:trpt1
gene id: 8128:trpt1
uniprot id: I3JCW7
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

8128:hgs
gene id: 8128:hgs
uniprot id: I3J0V8
names: Subcellular Location Annotation
messages: Early endosome membrane

8128:LOC100694843
gene id: 8128:LOC100694843
uniprot id: I3KYD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100691933
gene id: 8128:LOC100691933
uniprot id: A0A669C2S2
names: Similarity
messages: Belongs to the MHC class I family.

8128:rabggtb
gene id: 8128:rabggtb
uniprot id: A0A669AZC3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

8128:pkn2
gene id: 8128:pkn2
uniprot id: A0A669BFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

8128:adcy7
gene id: 8128:adcy7
uniprot id: A0A669BGH4
uniprot id: I3J3Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8128:mettl15
gene id: 8128:mettl15
uniprot id: I3J4E1
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

8128:cyld
gene id: 8128:cyld
uniprot id: A0A669BE33
uniprot id: A0A669DVL8
uniprot id: I3J3W1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

8128:fam234a
gene id: 8128:fam234a
uniprot id: I3KVG4
names: Similarity
messages: Belongs to the FAM234 family.

8128:gins1
gene id: 8128:gins1
uniprot id: A0A669BHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

8128:LOC100701336
gene id: 8128:LOC100701336
uniprot id: I3KTS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100697618
gene id: 8128:LOC100697618
uniprot id: I3JD99
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:eloa
gene id: 8128:eloa
uniprot id: I3KMM9
names: Subcellular Location Annotation
messages: Nucleus

8128:naca
gene id: 8128:naca
uniprot id: Q8AWF2
names: Function
names: Similarity
messages: Belongs to the NAC-alpha family.
messages: May promote appropriate targeting of ribosome-nascent polypeptide complexes.

8128:pfdn1
gene id: 8128:pfdn1
uniprot id: I3KMU0
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

8128:LOC100693258
gene id: 8128:LOC100693258
uniprot id: A0A669BHK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100708625
gene id: 8128:LOC100708625
uniprot id: A0A669E484
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

8128:sigmar1
gene id: 8128:sigmar1
uniprot id: A0A669CFH4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle

8128:LOC100700804
gene id: 8128:LOC100700804
uniprot id: I3IXG5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8128:LOC109201343
gene id: 8128:LOC109201343
uniprot id: A0A669BS28
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100705480
gene id: 8128:LOC100705480
uniprot id: I3KXX2
names: Subcellular Location Annotation
messages: Nucleus

8128:thrb
gene id: 8128:thrb
uniprot id: A0A669CGQ3
uniprot id: S5SY58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:ngrn
gene id: 8128:ngrn
uniprot id: I3J2R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

8128:LOC100690837
gene id: 8128:LOC100690837
uniprot id: I3K546
names: Similarity
messages: Belongs to the thioredoxin family.

8128:neu3e
gene id: 8128:neu3e
uniprot id: I3KNS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8128:LOC100692367
gene id: 8128:LOC100692367
uniprot id: I3J1U2
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8128:LOC102076176
gene id: 8128:LOC102076176
uniprot id: A0A669D131
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707774
gene id: 8128:LOC100707774
uniprot id: I3KV16
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8128:LOC100697339
gene id: 8128:LOC100697339
uniprot id: A0A669E7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8128:LOC100699123
gene id: 8128:LOC100699123
uniprot id: A0A669EF02
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100705618
gene id: 8128:LOC100705618
uniprot id: A0A669DYL2
uniprot id: A0A669ESU2
names: Subcellular Location Annotation
messages: Membrane

8128:lg22h1orf43
gene id: 8128:lg22h1orf43
uniprot id: I3KUQ1
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

8128:dcaf10
gene id: 8128:dcaf10
uniprot id: I3IVB3
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

8128:dync1li2
gene id: 8128:dync1li2
uniprot id: A0A669EBV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

8128:LOC100702158
gene id: 8128:LOC100702158
uniprot id: I3J058
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8128:gadd45b
gene id: 8128:gadd45b
uniprot id: I3JK22
names: Similarity
messages: Belongs to the GADD45 family.

8128:LOC100701851
gene id: 8128:LOC100701851
uniprot id: A0A669EE93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

8128:LOC102076498
gene id: 8128:LOC102076498
uniprot id: I3JDV5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8128:foxl2
gene id: 8128:foxl2
uniprot id: Q6JA05
names: Subcellular Location Annotation
messages: Nucleus

8128:cldn18
gene id: 8128:cldn18
uniprot id: I3KT07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:etnppl
gene id: 8128:etnppl
uniprot id: A0A669BC09
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

8128:aff4
gene id: 8128:aff4
uniprot id: I3JP24
names: Similarity
messages: Belongs to the AF4 family.

8128:exoc4
gene id: 8128:exoc4
uniprot id: A0A669F3T3
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

8128:aff3
gene id: 8128:aff3
uniprot id: I3K9J5
names: Similarity
messages: Belongs to the AF4 family.

8128:LOC100695964
gene id: 8128:LOC100695964
uniprot id: A0A669EGT9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8128:nt5c3a
gene id: 8128:nt5c3a
uniprot id: A0A669AY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8128:LOC100698635
gene id: 8128:LOC100698635
uniprot id: I3J2K5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100711784
gene id: 8128:LOC100711784
uniprot id: I3KKF5
names: Similarity
messages: Belongs to the CDR2 family.

8128:paip2
gene id: 8128:paip2
uniprot id: A0A669EX85
names: Similarity
messages: Belongs to the PAIP2 family.

8128:fyn
gene id: 8128:fyn
uniprot id: A0A669B9Z0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:LOC109204054
gene id: 8128:LOC109204054
uniprot id: A0A669C0Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:mcoln3
gene id: 8128:mcoln3
uniprot id: I3JQN6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8128:cdc42
gene id: 8128:cdc42
uniprot id: A0A669E3B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8128:LOC100708397
gene id: 8128:LOC100708397
uniprot id: A0A669AYT7
uniprot id: I3JRT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8128:LOC109202971
gene id: 8128:LOC109202971
uniprot id: A0A669DD40
names: Similarity
messages: Belongs to the helicase family.

8128:LOC100699505
gene id: 8128:LOC100699505
uniprot id: A0A669EBD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

8128:LOC100697794
gene id: 8128:LOC100697794
uniprot id: I3KP74
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8128:map3k5
gene id: 8128:map3k5
uniprot id: A0A669B1F5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8128:LOC100711637
gene id: 8128:LOC100711637
uniprot id: A0A669DM07
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8128:LOC109196662
gene id: 8128:LOC109196662
uniprot id: A0A669ET05
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100705058
gene id: 8128:LOC100705058
uniprot id: A0A669DWR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

8128:rnd3
gene id: 8128:rnd3
uniprot id: A0A669B225
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

8128:LOC100700034
gene id: 8128:LOC100700034
uniprot id: I3JKE3
names: Similarity
messages: Belongs to the DNase II family.

8128:tmem205
gene id: 8128:tmem205
uniprot id: I3JMN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

8128:LOC100706692
gene id: 8128:LOC100706692
uniprot id: A0A669EKN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100698775
gene id: 8128:LOC100698775
uniprot id: A0A669EQB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

8128:LOC106098924
gene id: 8128:LOC106098924
uniprot id: A0A669D632
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:LOC100693503
gene id: 8128:LOC100693503
uniprot id: A0A669AX82
names: Similarity
messages: Belongs to the MAGUK family.

8128:LOC100693591
gene id: 8128:LOC100693591
uniprot id: I3J2H2
names: Subcellular Location Annotation
messages: Membrane
messages: extracellular matrix

8128:LOC100703983
gene id: 8128:LOC100703983
uniprot id: A0A669EAA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8128:olfm3
gene id: 8128:olfm3
uniprot id: I3JB53
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8128:ubald2
gene id: 8128:ubald2
uniprot id: A0A669FAK8
names: Similarity
messages: Belongs to the UBALD family.

8128:LOC102080261
gene id: 8128:LOC102080261
uniprot id: I3KD31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

8128:LOC100694055
gene id: 8128:LOC100694055
uniprot id: I3JXU1
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8128:kcnk13
gene id: 8128:kcnk13
uniprot id: I3IXX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:etfdh
gene id: 8128:etfdh
uniprot id: A0A669BNY9
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

8128:dpys
gene id: 8128:dpys
uniprot id: A0A669DRM8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

8128:LOC109201907
gene id: 8128:LOC109201907
uniprot id: A0A669DXY9
names: Similarity
messages: Belongs to the globin family.

8128:LOC102082288
gene id: 8128:LOC102082288
uniprot id: A0A669DF40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8128:LOC102079134
gene id: 8128:LOC102079134
uniprot id: I3KMX9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100708611
gene id: 8128:LOC100708611
uniprot id: I3KAG0
names: Similarity
messages: Belongs to the RBR family.

8128:mrps27
gene id: 8128:mrps27
uniprot id: I3KDI3
names: Subcellular Location Annotation
messages: Mitochondrion

8128:LOC102077296
gene id: 8128:LOC102077296
uniprot id: A0A669CI76
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:tcta
gene id: 8128:tcta
uniprot id: A0A669CMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: Membrane

8128:dtna
gene id: 8128:dtna
uniprot id: A0A669B393
uniprot id: A0A669E3T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

8128:LOC100704050
gene id: 8128:LOC100704050
uniprot id: A0A669EI78
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8128:LOC100712082
gene id: 8128:LOC100712082
uniprot id: I3K223
names: Subcellular Location Annotation
messages: Membrane

8128:rag2
gene id: 8128:rag2
uniprot id: I3KXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

8128:anapc16
gene id: 8128:anapc16
uniprot id: A0A669B135
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

8128:LOC109203641
gene id: 8128:LOC109203641
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:sf3b6
gene id: 8128:sf3b6
uniprot id: A0A669F9C8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC112841620
gene id: 8128:LOC112841620
uniprot id: I3JAN5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

8128:fam126a
gene id: 8128:fam126a
uniprot id: I3J0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8128:LOC100711149
gene id: 8128:LOC100711149
uniprot id: A0A669CIL0
names: Similarity
messages: Belongs to the beta-catenin family.

8128:adgrb2
gene id: 8128:adgrb2
uniprot id: A0A669D6C3
uniprot id: A0A669F8P8
names: Subcellular Location Annotation
messages: Membrane

8128:mad1l1
gene id: 8128:mad1l1
uniprot id: I3IUB8
names: Similarity
messages: Belongs to the MAD1 family.

8128:ppif
gene id: 8128:ppif
uniprot id: I3KQB9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:cct2
gene id: 8128:cct2
uniprot id: I3Y505
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8128:mapre1
gene id: 8128:mapre1
uniprot id: I3KC33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8128:LOC100692879
gene id: 8128:LOC100692879
uniprot id: I3KYQ6
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8128:LOC100699981
gene id: 8128:LOC100699981
uniprot id: A0A669CHK7
uniprot id: I3KVU6
uniprot id: I3KVU7
names: Subcellular Location Annotation
messages: Membrane

8128:ansn
gene id: 8128:ansn
uniprot id: Q3LHN4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

8128:rnaseh1
gene id: 8128:rnaseh1
uniprot id: I3KQZ3
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

8128:LOC100698247
gene id: 8128:LOC100698247
uniprot id: I3KQZ1
names: Similarity
messages: Belongs to the GORASP family.

8128:LOC100690617
gene id: 8128:LOC100690617
uniprot id: I3L032
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:cpne2
gene id: 8128:cpne2
uniprot id: I3JYW0
names: Similarity
messages: Belongs to the copine family.

8128:sart1
gene id: 8128:sart1
uniprot id: I3KZN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

8128:LOC100697817
gene id: 8128:LOC100697817
uniprot id: A0A669EWS7
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

8128:LOC102080391
gene id: 8128:LOC102080391
uniprot id: A0A669BM86
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.

8128:LOC100709409
gene id: 8128:LOC100709409
uniprot id: I3KSW9
uniprot id: I3KSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8128:agap3
gene id: 8128:agap3
uniprot id: A0A669EAU9
names: Similarity
messages: Belongs to the centaurin gamma-like family.

8128:LOC100704795
gene id: 8128:LOC100704795
uniprot id: I3JP45
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8128:mis18a
gene id: 8128:mis18a
uniprot id: A0A669CD33
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

8128:LOC100712573
gene id: 8128:LOC100712573
uniprot id: A0A0E3M3Y5
uniprot id: A0A669FAX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

8128:zhx2
gene id: 8128:zhx2
uniprot id: I3JJZ8
uniprot id: I3JJZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8128:scg3
gene id: 8128:scg3
uniprot id: I3IUC4
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

8128:brcc3
gene id: 8128:brcc3
uniprot id: I3KZ08
names: Similarity
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.

8128:LOC100694928
gene id: 8128:LOC100694928
uniprot id: A0A669AYB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

8128:LOC100704945
gene id: 8128:LOC100704945
uniprot id: I3IVW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8128:vipas39
gene id: 8128:vipas39
uniprot id: I3KS64
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Late endosome

8128:rnf157
gene id: 8128:rnf157
uniprot id: A0A669E060
uniprot id: A0A669EUX1
uniprot id: I3KVL2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

8128:LOC100708768
gene id: 8128:LOC100708768
uniprot id: A0A669D636
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100705658
gene id: 8128:LOC100705658
uniprot id: A0A669AVA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:ublcp1
gene id: 8128:ublcp1
uniprot id: I3JPP7
names: Subcellular Location Annotation
messages: Nucleus

8128:wdr35
gene id: 8128:wdr35
uniprot id: I3KU12
uniprot id: I3KU14
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

8128:ghrh
gene id: 8128:ghrh
uniprot id: I3KWM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8128:ndufs5
gene id: 8128:ndufs5
uniprot id: A0A669BUV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

8128:pi4k2b
gene id: 8128:pi4k2b
uniprot id: I3J6C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

8128:LOC100698191
gene id: 8128:LOC100698191
uniprot id: A0A669C5V3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100702455
gene id: 8128:LOC100702455
uniprot id: A0A669CQC1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8128:LOC109201904
gene id: 8128:LOC109201904
uniprot id: A0A669DXY9
names: Similarity
messages: Belongs to the globin family.

8128:LOC100699786
gene id: 8128:LOC100699786
uniprot id: I3JLS6
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:calhm1
gene id: 8128:calhm1
uniprot id: A0A669CJ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

8128:pcyt2
gene id: 8128:pcyt2
uniprot id: A0A669BDF0
names: Similarity
messages: Belongs to the cytidylyltransferase family.

8128:LOC100702641
gene id: 8128:LOC100702641
uniprot id: I3J854
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8128:LOC100694231
gene id: 8128:LOC100694231
uniprot id: A0A669ECW2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC109200246
gene id: 8128:LOC109200246
uniprot id: I3IU67
names: Similarity
messages: Belongs to the asteroid family.

8128:LOC100705942
gene id: 8128:LOC100705942
uniprot id: A0A669F994
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100692739
gene id: 8128:LOC100692739
uniprot id: I3KF40
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:mnd1
gene id: 8128:mnd1
uniprot id: A0A669BC57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

8128:slc26a6
gene id: 8128:slc26a6
uniprot id: I3IZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8128:LOC100702940
gene id: 8128:LOC100702940
uniprot id: I3KFB7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: extracellular space

8128:LOC100698414
gene id: 8128:LOC100698414
uniprot id: A0A669BXN9
uniprot id: I3KGV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8128:ccdc93
gene id: 8128:ccdc93
uniprot id: I3KLI1
names: Similarity
messages: Belongs to the CCDC93 family.

8128:LOC100703046
gene id: 8128:LOC100703046
uniprot id: I3KJG5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8128:LOC100710068
gene id: 8128:LOC100710068
uniprot id: I3JGV9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8128:LOC100689908
gene id: 8128:LOC100689908
uniprot id: I3J221
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:blm
gene id: 8128:blm
uniprot id: A0A669C3Z0
uniprot id: I3KDC9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

8128:LOC100692161
gene id: 8128:LOC100692161
uniprot id: A0A669BSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: Secreted

8128:loxl3
gene id: 8128:loxl3
uniprot id: A0A669BNP6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8128:LOC100694186
gene id: 8128:LOC100694186
uniprot id: I3K821
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:apoc2
gene id: 8128:apoc2
uniprot id: I7J7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C2 family.
messages: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
messages: Secreted

8128:psmg2
gene id: 8128:psmg2
uniprot id: I3J3E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

8128:pgp
gene id: 8128:pgp
uniprot id: I3KUW7
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

8128:LOC100700270
gene id: 8128:LOC100700270
uniprot id: I3KWT0
names: Similarity
messages: Belongs to the Bcl-2 family.

8128:otop1
gene id: 8128:otop1
uniprot id: I3KX21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

8128:LOC100694761
gene id: 8128:LOC100694761
uniprot id: F8TJX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8128:LOC100696694
gene id: 8128:LOC100696694
uniprot id: I3KC04
names: Similarity
messages: Belongs to the PROTOR family.

8128:dvl2
gene id: 8128:dvl2
uniprot id: A0A669EQF0
names: Similarity
messages: Belongs to the DSH family.

8128:LOC100703297
gene id: 8128:LOC100703297
uniprot id: I3J6Z2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709157
gene id: 8128:LOC100709157
uniprot id: I3J027
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:hscb
gene id: 8128:hscb
uniprot id: I3JWY0
names: Similarity
messages: Belongs to the HscB family.

8128:LOC100711526
gene id: 8128:LOC100711526
uniprot id: I3IWK4
names: Similarity
messages: Belongs to the peptidase S1C family.

8128:ccdc25
gene id: 8128:ccdc25
uniprot id: A0A669CNA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

8128:LOC100703315
gene id: 8128:LOC100703315
uniprot id: I3KDE9
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8128:LOC100708305
gene id: 8128:LOC100708305
uniprot id: A0A669DWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:LOC100697562
gene id: 8128:LOC100697562
uniprot id: I3J8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8128:LOC100706089
gene id: 8128:LOC100706089
uniprot id: I3KZQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:LOC100698346
gene id: 8128:LOC100698346
uniprot id: A0A669CSD6
uniprot id: A0A669E351
uniprot id: I3JQR1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8128:rem1
gene id: 8128:rem1
uniprot id: I3IVT9
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8128:LOC100692909
gene id: 8128:LOC100692909
uniprot id: A0A669CJT8
uniprot id: A0A669F1X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8128:LOC100702604
gene id: 8128:LOC100702604
uniprot id: I3K5F1
names: Similarity
messages: Belongs to the cholesterol 7-desaturase family.

8128:LOC100709357
gene id: 8128:LOC100709357
uniprot id: A0A669CSL3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690431
gene id: 8128:LOC100690431
uniprot id: A0A669BD49
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC100695571
gene id: 8128:LOC100695571
uniprot id: A0A669DV03
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:tmem199
gene id: 8128:tmem199
uniprot id: A0A669E864
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:nmt1
gene id: 8128:nmt1
uniprot id: A0A669B1Y4
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

8128:LOC100693976
gene id: 8128:LOC100693976
uniprot id: A0A669CA13
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a role in the process of neurogenesis.

8128:tmem39b
gene id: 8128:tmem39b
uniprot id: I3K2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

8128:prkg2
gene id: 8128:prkg2
uniprot id: I3K956
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8128:myo5b
gene id: 8128:myo5b
uniprot id: A0A669EVL9
uniprot id: I3K8N1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100698622
gene id: 8128:LOC100698622
uniprot id: I3J561
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

8128:supt20h
gene id: 8128:supt20h
uniprot id: I3K412
names: Similarity
messages: Belongs to the SPT20 family.

8128:LOC100711601
gene id: 8128:LOC100711601
uniprot id: A0A669DUY6
names: Similarity
messages: Belongs to the cornifelin family.

8128:LOC100690386
gene id: 8128:LOC100690386
uniprot id: I3KZD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC109204576
gene id: 8128:LOC109204576
uniprot id: A0A669E139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8128:LOC100708764
gene id: 8128:LOC100708764
uniprot id: I3KTX3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100694329
gene id: 8128:LOC100694329
uniprot id: A0A669CIJ5
names: Subcellular Location Annotation
messages: Membrane

8128:orc3
gene id: 8128:orc3
uniprot id: I3J6R2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

8128:LOC100692397
gene id: 8128:LOC100692397
uniprot id: A0A669CFW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:henmt1
gene id: 8128:henmt1
uniprot id: I3JNS4
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

8128:pou1f1
gene id: 8128:pou1f1
uniprot id: I3J944
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8128:itpk1
gene id: 8128:itpk1
uniprot id: A0A669DM01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ITPK1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.
messages: Monomer.

8128:ube2g1
gene id: 8128:ube2g1
uniprot id: I3KLT5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:rad54l
gene id: 8128:rad54l
uniprot id: I3JLA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Interacts (via N-terminus) with spn-A/Rad51.
messages: Involved in mitotic DNA repair and meiotic recombination. Functions in the recombinational DNA repair pathway. Essential for interhomolog gene conversion (GC), but may have a less important role in intersister GC than spn-A/Rad51. In the presence of DNA, spn-A/Rad51 enhances the ATPase activity of okr/Rad54.

8128:LOC100711673
gene id: 8128:LOC100711673
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:gucy1a2
gene id: 8128:gucy1a2
uniprot id: I3JBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

8128:patj
gene id: 8128:patj
uniprot id: I3JAB9
names: Subcellular Location Annotation
messages: tight junction

8128:nrp2
gene id: 8128:nrp2
uniprot id: A0A669EMI6
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:myog
gene id: 8128:myog
uniprot id: D2XRC2
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8128:dnmbp
gene id: 8128:dnmbp
uniprot id: A0A669CJX2
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

8128:crat
gene id: 8128:crat
uniprot id: I3JY04
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8128:LOC100710302
gene id: 8128:LOC100710302
uniprot id: I3L056
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:hdac5
gene id: 8128:hdac5
uniprot id: I3JGK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8128:ndufs4
gene id: 8128:ndufs4
uniprot id: A0A669CQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

8128:phf8
gene id: 8128:phf8
uniprot id: I3K1X4
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8128:LOC100705398
gene id: 8128:LOC100705398
uniprot id: A0A669EBC3
names: Similarity
messages: Belongs to the peptidase M14 family.

8128:slc16a10
gene id: 8128:slc16a10
uniprot id: I3JZN1
names: Subcellular Location Annotation
messages: Membrane

8128:lcmt1
gene id: 8128:lcmt1
uniprot id: I3KUV4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

8128:melk
gene id: 8128:melk
uniprot id: A0A669DVI0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

8128:hibch
gene id: 8128:hibch
uniprot id: I3JJI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

8128:myorg
gene id: 8128:myorg
uniprot id: I3KTQ0
uniprot id: I3KTQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Belongs to the nicastrin family.

8128:fam193b
gene id: 8128:fam193b
uniprot id: I3KMS6
names: Similarity
messages: Belongs to the FAM193 family.

8128:LOC100704256
gene id: 8128:LOC100704256
uniprot id: I3KCZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:LOC100695734
gene id: 8128:LOC100695734
uniprot id: I3JNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8128:cmpk1
gene id: 8128:cmpk1
uniprot id: A0A669ET28
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

8128:LOC100701614
gene id: 8128:LOC100701614
uniprot id: A0A669AVQ8
uniprot id: I3J282
names: Subcellular Location Annotation
messages: extracellular space

8128:ell2
gene id: 8128:ell2
uniprot id: A0A669C0A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8128:sulf1
gene id: 8128:sulf1
uniprot id: A0A669CPV1
uniprot id: A0A669E1K5
uniprot id: A0A669EEA6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:LOC100707370
gene id: 8128:LOC100707370
uniprot id: I3K7A8
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

8128:LOC100693747
gene id: 8128:LOC100693747
uniprot id: A0A669EDM6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

8128:pax3
gene id: 8128:pax3
uniprot id: I3KBC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:cks1b
gene id: 8128:cks1b
uniprot id: I3KUN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

8128:rgs9
gene id: 8128:rgs9
uniprot id: I3JMI2
names: Subcellular Location Annotation
messages: Membrane

8128:serpine1
gene id: 8128:serpine1
uniprot id: I3JIL1
names: Similarity
messages: Belongs to the serpin family.

8128:LOC100695726
gene id: 8128:LOC100695726
uniprot id: I3IVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8128:LOC100704949
gene id: 8128:LOC100704949
uniprot id: A0A669CW90
uniprot id: I3JRV7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

8128:fnip1
gene id: 8128:fnip1
uniprot id: A0A669DB14
uniprot id: I3KKU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

8128:LOC100698187
gene id: 8128:LOC100698187
uniprot id: A0A669CVV0
uniprot id: A0A669DC81
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100701140
gene id: 8128:LOC100701140
uniprot id: A0A669B530
names: Similarity
messages: Belongs to the syntaxin family.

8128:LOC100705489
gene id: 8128:LOC100705489
uniprot id: A0A669B8F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:arpc1a
gene id: 8128:arpc1a
uniprot id: A0A669C5T8
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

8128:LOC100695265
gene id: 8128:LOC100695265
uniprot id: A0A669F0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8128:nfib
gene id: 8128:nfib
uniprot id: A0A669DDG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

8128:LOC100695310
gene id: 8128:LOC100695310
uniprot id: I3JRN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC109204161
gene id: 8128:LOC109204161
uniprot id: I3JZX0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

8128:LOC100706564
gene id: 8128:LOC100706564
uniprot id: I3K788
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8128:pmvk
gene id: 8128:pmvk
uniprot id: I3IYT1
names: Subcellular Location Annotation
messages: cytosol

8128:tbl3
gene id: 8128:tbl3
uniprot id: I3J206
names: Subcellular Location Annotation
messages: nucleolus

8128:LOC100699154
gene id: 8128:LOC100699154
uniprot id: A0A669B745
uniprot id: A0A669B9A4
uniprot id: A0A669EU10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nectin family.
messages: Membrane

8128:fat3
gene id: 8128:fat3
uniprot id: A0A669BJQ3
uniprot id: A0A669E3E4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ap1b1
gene id: 8128:ap1b1
uniprot id: A0A669C5R2
uniprot id: A0A669C6S1
uniprot id: A0A669D8H7
uniprot id: A0A669DRW5
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8128:naa25
gene id: 8128:naa25
uniprot id: A0A669DX79
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

8128:LOC100709596
gene id: 8128:LOC100709596
uniprot id: A0A669CIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8128:LOC100697593
gene id: 8128:LOC100697593
uniprot id: A0A669CAK3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100705061
gene id: 8128:LOC100705061
uniprot id: A0A669DF82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

8128:LOC100699564
gene id: 8128:LOC100699564
uniprot id: A0A669AWI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100712419
gene id: 8128:LOC100712419
uniprot id: A0A669DCB9
names: Subcellular Location Annotation
messages: Membrane

8128:pet117
gene id: 8128:pet117
uniprot id: A0A669EWA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

8128:LOC100705567
gene id: 8128:LOC100705567
uniprot id: I3K5K8
uniprot id: I3K5K9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8128:arrdc3
gene id: 8128:arrdc3
uniprot id: A0A669C1N4
names: Similarity
messages: Belongs to the arrestin family.

8128:clul1
gene id: 8128:clul1
uniprot id: I3JFL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

8128:agbl5
gene id: 8128:agbl5
uniprot id: A0A669C8I9
uniprot id: I3IXK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

8128:slu7
gene id: 8128:slu7
uniprot id: I3K5A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

8128:uros
gene id: 8128:uros
uniprot id: A0A669AYF8
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

8128:LOC100692670
gene id: 8128:LOC100692670
uniprot id: I3JR87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

8128:mboat7
gene id: 8128:mboat7
uniprot id: I3K4K3
names: Subcellular Location Annotation
messages: Membrane

8128:zar1
gene id: 8128:zar1
uniprot id: I3J4P9
names: Similarity
messages: Belongs to the ZAR1 family.

8128:LOC100706654
gene id: 8128:LOC100706654
uniprot id: A0A669F2G3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102079808
gene id: 8128:LOC102079808
uniprot id: A0A669B3H5
names: Similarity
messages: Belongs to the cornifelin family.

8128:LOC100709663
gene id: 8128:LOC100709663
uniprot id: A0A669CUR1
names: Subcellular Location Annotation
messages: Nucleus

8128:trim45
gene id: 8128:trim45
uniprot id: A0A669CXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

8128:LOC100698842
gene id: 8128:LOC100698842
uniprot id: I3KT86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8128:LOC100704832
gene id: 8128:LOC100704832
uniprot id: I3JM16
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709311
gene id: 8128:LOC100709311
uniprot id: A0A669BJZ5
uniprot id: A0A669CQ82
uniprot id: A0A669DW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

8128:ltbp3
gene id: 8128:ltbp3
uniprot id: I3JCP8
uniprot id: I3JCP9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:usp49
gene id: 8128:usp49
uniprot id: I3KRU8
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:LOC100690724
gene id: 8128:LOC100690724
uniprot id: I3JEZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:LOC100696786
gene id: 8128:LOC100696786
uniprot id: A0A669DVG2
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

8128:LOC100707121
gene id: 8128:LOC100707121
uniprot id: A0A669B6A3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:srp68
gene id: 8128:srp68
uniprot id: A0A669CT78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

8128:LOC100690502
gene id: 8128:LOC100690502
uniprot id: A0A669CBJ7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100703924
gene id: 8128:LOC100703924
uniprot id: A0A023ZXY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

8128:ak5
gene id: 8128:ak5
uniprot id: I3KPS9
names: Similarity
messages: Belongs to the adenylate kinase family.

8128:nudt1
gene id: 8128:nudt1
uniprot id: A0A669D9F9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

8128:LOC100694290
gene id: 8128:LOC100694290
uniprot id: A0A669B6S0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8128:LOC100691030
gene id: 8128:LOC100691030
uniprot id: A0A669CLA2
names: Similarity
messages: Belongs to the RELT family.

8128:lox
gene id: 8128:lox
uniprot id: I3K8A2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8128:LOC100689746
gene id: 8128:LOC100689746
uniprot id: I3K0V0
names: Similarity
messages: Belongs to the PROTOR family.

8128:LOC100700876
gene id: 8128:LOC100700876
uniprot id: I3KUP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8128:LOC100702938
gene id: 8128:LOC100702938
uniprot id: I3JLI3
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8128:p2ry4
gene id: 8128:p2ry4
uniprot id: I3KXQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100709989
gene id: 8128:LOC100709989
uniprot id: I3KHG7
names: Subcellular Location Annotation
messages: Cytoplasm

8128:ddx3x
gene id: 8128:ddx3x
uniprot id: A0A669CLE5
uniprot id: A0A669F192
uniprot id: I3KH65
uniprot id: I3KH66
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:wdr44
gene id: 8128:wdr44
uniprot id: I3JCN2
names: Subcellular Location Annotation
messages: trans-Golgi network

8128:LOC100691455
gene id: 8128:LOC100691455
uniprot id: A0A669C6W5
names: Subcellular Location Annotation
messages: Synapse

8128:LOC100704478
gene id: 8128:LOC100704478
uniprot id: I3JAR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8128:cdc42ep5
gene id: 8128:cdc42ep5
uniprot id: A0A669BW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8128:LOC109204497
gene id: 8128:LOC109204497
uniprot id: I3KYL6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:pdgfrb
gene id: 8128:pdgfrb
uniprot id: I3K5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Interacts with homodimeric PDGFB and PDGFD, and with heterodimers formed by PDGFA and PDGFB.
messages: Lysosome lumen
messages: Membrane
messages: Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
messages: Vesicle

8128:LOC100704453
gene id: 8128:LOC100704453
uniprot id: A0A669B252
uniprot id: A0A669CFI3
uniprot id: A0A669EUQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

8128:LOC100698042
gene id: 8128:LOC100698042
uniprot id: I3JJ67
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100702646
gene id: 8128:LOC100702646
uniprot id: I3KH46
names: Similarity
messages: Belongs to the ZC3H12 family.

8128:LOC100691170
gene id: 8128:LOC100691170
uniprot id: A0A669F5G4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8128:ppara
gene id: 8128:ppara
uniprot id: A0A669E8P6
uniprot id: W6A350
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:LOC100700156
gene id: 8128:LOC100700156
uniprot id: A0A669ELL5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

8128:LOC100707429
gene id: 8128:LOC100707429
uniprot id: I3KCQ2
names: Similarity
messages: Belongs to the SAPS family.

8128:LOC100693496
gene id: 8128:LOC100693496
uniprot id: I3K0L2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699578
gene id: 8128:LOC100699578
uniprot id: A0A669D0E1
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8128:LOC100708699
gene id: 8128:LOC100708699
uniprot id: A0A669C7K7
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

8128:LOC100700585
gene id: 8128:LOC100700585
uniprot id: A0A669B8B6
names: Similarity
messages: Belongs to the arrestin family.

8128:LOC100703221
gene id: 8128:LOC100703221
uniprot id: I3J305
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cnnm2
gene id: 8128:cnnm2
uniprot id: A0A669DB68
uniprot id: I3KRG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

8128:LOC100692540
gene id: 8128:LOC100692540
uniprot id: I3K4V5
names: Similarity
messages: Belongs to the sorting nexin family.

8128:mst1
gene id: 8128:mst1
uniprot id: I3J849
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:pgr
gene id: 8128:pgr
uniprot id: A0A669C0L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:LOC100707496
gene id: 8128:LOC100707496
uniprot id: A0A669BAC8
uniprot id: A0A669EAP4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:snrpb
gene id: 8128:snrpb
uniprot id: A0A669EPA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

8128:lrig3
gene id: 8128:lrig3
uniprot id: A0A669CGF3
uniprot id: A0A669E2Y5
names: Subcellular Location Annotation
messages: Membrane

8128:eif4enif1
gene id: 8128:eif4enif1
uniprot id: A0A669ETC2
names: Subcellular Location Annotation
messages: Cytoplasm

8128:mrps14
gene id: 8128:mrps14
uniprot id: I3JUB8
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

8128:slc26a11
gene id: 8128:slc26a11
uniprot id: A0A669E9T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8128:LOC100691663
gene id: 8128:LOC100691663
uniprot id: I3JIH8
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:ak3
gene id: 8128:ak3
uniprot id: A0A669CV18
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

8128:gclc
gene id: 8128:gclc
uniprot id: I3JTI9
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

8128:tmem14a
gene id: 8128:tmem14a
uniprot id: I3JTF8
names: Similarity
messages: Belongs to the TMEM14 family.

8128:fam126b
gene id: 8128:fam126b
uniprot id: A0A669BYB6
uniprot id: A0A669C839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8128:LOC100696456
gene id: 8128:LOC100696456
uniprot id: I3KQ48
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC102080669
gene id: 8128:LOC102080669
uniprot id: I3KRX7
names: Similarity
messages: Belongs to the EPS8 family.

8128:LOC100699358
gene id: 8128:LOC100699358
uniprot id: I3JXD1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8128:plin2
gene id: 8128:plin2
uniprot id: W0NU89
names: Similarity
messages: Belongs to the perilipin family.

8128:LOC100691118
gene id: 8128:LOC100691118
uniprot id: I3JFC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

8128:fh
gene id: 8128:fh
uniprot id: I3KYC9
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

8128:LOC100697026
gene id: 8128:LOC100697026
uniprot id: A0A669AV75
names: Similarity
messages: Belongs to the AccD/PCCB family.

8128:rab4a
gene id: 8128:rab4a
uniprot id: I3KK77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

8128:LOC100702877
gene id: 8128:LOC100702877
uniprot id: I3JVT6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

8128:LOC100534568
gene id: 8128:LOC100534568
uniprot id: B9UN12
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8128:fmnl3
gene id: 8128:fmnl3
uniprot id: I3K2J1
names: Similarity
messages: Belongs to the formin homology family.

8128:pcsk2
gene id: 8128:pcsk2
uniprot id: I3IUZ6
names: Similarity
messages: Belongs to the peptidase S8 family.

8128:LOC100708728
gene id: 8128:LOC100708728
uniprot id: A0A669BED9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:grpel1
gene id: 8128:grpel1
uniprot id: A0A669DFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

8128:rfx3
gene id: 8128:rfx3
uniprot id: I3K946
names: Subcellular Location Annotation
messages: Nucleus

8128:il-8
gene id: 8128:il-8
uniprot id: A0A669EVS8
uniprot id: C7FF37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8128:LOC100692823
gene id: 8128:LOC100692823
uniprot id: A0A0E3JI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

8128:specc1l
gene id: 8128:specc1l
uniprot id: I3KG22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

8128:LOC100697225
gene id: 8128:LOC100697225
uniprot id: I3K4P3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:sept6
gene id: 8128:sept6
uniprot id: A0A669CWC0
uniprot id: I3J2S5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:LOC100693683
gene id: 8128:LOC100693683
uniprot id: A0A669CDD6
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

8128:comp
gene id: 8128:comp
uniprot id: I3K468
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:bsx
gene id: 8128:bsx
uniprot id: A0A669ESL3
names: Subcellular Location Annotation
messages: Nucleus

8128:nr1h4
gene id: 8128:nr1h4
uniprot id: A0A669EZ98
uniprot id: I3KBI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:LOC100700192
gene id: 8128:LOC100700192
uniprot id: A0A669EHF4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100701077
gene id: 8128:LOC100701077
uniprot id: I3KGI0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC102078595
gene id: 8128:LOC102078595
uniprot id: A0A669B254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:pld3
gene id: 8128:pld3
uniprot id: A0A669BTF2
names: Similarity
messages: Belongs to the phospholipase D family.

8128:LOC100711713
gene id: 8128:LOC100711713
uniprot id: I3KVA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8128:dohh
gene id: 8128:dohh
uniprot id: I3JLF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

8128:LOC100709590
gene id: 8128:LOC100709590
uniprot id: A0A669E4Y7
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100707754
gene id: 8128:LOC100707754
uniprot id: A0A669BNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:LOC100703311
gene id: 8128:LOC100703311
uniprot id: A0A669F5U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:pfdn6
gene id: 8128:pfdn6
uniprot id: A0A669CD01
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

8128:LOC100698519
gene id: 8128:LOC100698519
uniprot id: A0A669DSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:ddit3
gene id: 8128:ddit3
uniprot id: A0A669D239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

8128:ugcg
gene id: 8128:ugcg
uniprot id: A0A669D3I9
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

8128:LOC100690323
gene id: 8128:LOC100690323
uniprot id: I3K6A6
names: Similarity
messages: Belongs to the BTG family.

8128:LOC100694590
gene id: 8128:LOC100694590
uniprot id: A0A669AZ27
uniprot id: A0A669BK97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:tdo2
gene id: 8128:tdo2
uniprot id: I3IXW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100708428
gene id: 8128:LOC100708428
uniprot id: A0A669F4T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

8128:hnrnpk
gene id: 8128:hnrnpk
uniprot id: I3KCP3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm

8128:LOC100709849
gene id: 8128:LOC100709849
uniprot id: I3JYC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:itprip
gene id: 8128:itprip
uniprot id: I3KY31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

8128:LOC100707435
gene id: 8128:LOC100707435
uniprot id: I3IXS0
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:LOC100696646
gene id: 8128:LOC100696646
uniprot id: I3K6Q3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:ncdn
gene id: 8128:ncdn
uniprot id: I3K7Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

8128:LOC100707934
gene id: 8128:LOC100707934
uniprot id: A0A669CLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:mst1r
gene id: 8128:mst1r
uniprot id: I3KWR1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:mfsd5
gene id: 8128:mfsd5
uniprot id: A0A669CQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

8128:fam131a
gene id: 8128:fam131a
uniprot id: I3JXI1
names: Similarity
messages: Belongs to the FAM131 family.

8128:LOC109204384
gene id: 8128:LOC109204384
uniprot id: A0A669CAU2
names: Subcellular Location Annotation
messages: Cytoplasm

8128:hagh
gene id: 8128:hagh
uniprot id: I3KKQ9
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8128:LOC100690947
gene id: 8128:LOC100690947
uniprot id: I3J4T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

8128:ano4
gene id: 8128:ano4
uniprot id: I3K1K3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100699145
gene id: 8128:LOC100699145
uniprot id: I3KQA0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:rbm8a
gene id: 8128:rbm8a
uniprot id: A0A669FAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

8128:LOC100710803
gene id: 8128:LOC100710803
uniprot id: A0A669BA07
names: Similarity
messages: Belongs to the acylphosphatase family.

8128:mrpl17
gene id: 8128:mrpl17
uniprot id: I3JZT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

8128:LOC100697346
gene id: 8128:LOC100697346
uniprot id: A0A669BIH4
names: Subcellular Location Annotation
messages: Membrane

8128:anapc10
gene id: 8128:anapc10
uniprot id: I3K0T8
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

8128:LOC100693659
gene id: 8128:LOC100693659
uniprot id: I3JV45
names: Similarity
messages: Belongs to the EEIG family.

8128:LOC100693585
gene id: 8128:LOC100693585
uniprot id: A0A669E7Q6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8128:LOC100707085
gene id: 8128:LOC100707085
uniprot id: I3JEG6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:LOC100711981
gene id: 8128:LOC100711981
uniprot id: I3KVA5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100691448
gene id: 8128:LOC100691448
uniprot id: I3J3P0
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

8128:LOC100692412
gene id: 8128:LOC100692412
uniprot id: I3K279
names: Subcellular Location Annotation
messages: cytoskeleton

8128:LOC100707250
gene id: 8128:LOC100707250
uniprot id: I3JHL5
names: Similarity
messages: Belongs to the RBR family.

8128:isyna1
gene id: 8128:isyna1
uniprot id: I3IXX3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

8128:LOC100708195
gene id: 8128:LOC100708195
uniprot id: I3KXT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:sfxn2
gene id: 8128:sfxn2
uniprot id: I3KFL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

8128:nphs1
gene id: 8128:nphs1
uniprot id: I3J3Q6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100695331
gene id: 8128:LOC100695331
uniprot id: A0A669CZN3
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

8128:LOC100692957
gene id: 8128:LOC100692957
uniprot id: A0A669BX45
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696554
gene id: 8128:LOC100696554
uniprot id: A0A669EKR2
names: Similarity
messages: Belongs to the MAGUK family.

8128:gprc5a
gene id: 8128:gprc5a
uniprot id: I3JNP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100694078
gene id: 8128:LOC100694078
uniprot id: I3KPT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule

8128:LOC100710519
gene id: 8128:LOC100710519
uniprot id: I3K9Y3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100707308
gene id: 8128:LOC100707308
uniprot id: I3K413
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100705329
gene id: 8128:LOC100705329
uniprot id: A0A669EC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8128:b4galt3
gene id: 8128:b4galt3
uniprot id: I3K3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8128:LOC100699567
gene id: 8128:LOC100699567
uniprot id: I3KBV3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

8128:LOC100700418
gene id: 8128:LOC100700418
uniprot id: A0A669ENU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

8128:LOC100696228
gene id: 8128:LOC100696228
uniprot id: A0A669E2G8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:kdm3b
gene id: 8128:kdm3b
uniprot id: A0A669BEC8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

8128:LOC100701087
gene id: 8128:LOC100701087
uniprot id: I3KC89
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8128:LOC102079182
gene id: 8128:LOC102079182
uniprot id: A0A669C0W7
names: Subcellular Location Annotation
messages: Membrane

8128:mcu
gene id: 8128:mcu
uniprot id: A0A669E527
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

8128:il1rap
gene id: 8128:il1rap
uniprot id: I3IXZ6
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8128:ankrd13b
gene id: 8128:ankrd13b
uniprot id: A0A669C759
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8128:ins
gene id: 8128:ins
uniprot id: I3IUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

8128:rpf1
gene id: 8128:rpf1
uniprot id: I3JKC7
names: Subcellular Location Annotation
messages: nucleolus

8128:vamp7
gene id: 8128:vamp7
uniprot id: I3KM87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8128:hyls1
gene id: 8128:hyls1
uniprot id: I3IU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

8128:ttc4
gene id: 8128:ttc4
uniprot id: A0A669BDR7
names: Similarity
messages: Belongs to the TTC4 family.

8128:LOC100712230
gene id: 8128:LOC100712230
uniprot id: A0A669EUD1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8128:actr8
gene id: 8128:actr8
uniprot id: I3J0B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

8128:atg5
gene id: 8128:atg5
uniprot id: A0A669BCM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

8128:LOC100690308
gene id: 8128:LOC100690308
uniprot id: A0A669C1A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:camsap1
gene id: 8128:camsap1
uniprot id: A0A669D572
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8128:yipf6
gene id: 8128:yipf6
uniprot id: A0A669F6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:slc13a3
gene id: 8128:slc13a3
uniprot id: A0A669C018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8128:vgll4
gene id: 8128:vgll4
uniprot id: I3KA85
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8128:tmem38a
gene id: 8128:tmem38a
uniprot id: I3K478
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

8128:LOC100696908
gene id: 8128:LOC100696908
uniprot id: A0A669CGJ6
names: Subcellular Location Annotation
messages: Nucleus

8128:slc29a4
gene id: 8128:slc29a4
uniprot id: I3JP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

8128:uhrf2
gene id: 8128:uhrf2
uniprot id: I3K980
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

8128:ndufb6
gene id: 8128:ndufb6
uniprot id: I3KLX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8128:lg23h19orf70
gene id: 8128:lg23h19orf70
uniprot id: A0A669CWS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100697206
gene id: 8128:LOC100697206
uniprot id: I3J4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8128:LOC100695287
gene id: 8128:LOC100695287
uniprot id: Q9I9I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8128:znf703
gene id: 8128:znf703
uniprot id: A0A669CZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8128:LOC100712186
gene id: 8128:LOC100712186
uniprot id: I3J3E8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8128:LOC100707177
gene id: 8128:LOC100707177
uniprot id: I3J724
names: Similarity
messages: Belongs to the intermediate filament family.

8128:LOC100693123
gene id: 8128:LOC100693123
uniprot id: A0A669ELX2
names: Similarity
messages: Belongs to the peptidase C15 family.

8128:LOC100710420
gene id: 8128:LOC100710420
uniprot id: I3JHY9
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8128:LOC100699913
gene id: 8128:LOC100699913
uniprot id: I3IVA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:LOC100691027
gene id: 8128:LOC100691027
uniprot id: I3KRL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100692056
gene id: 8128:LOC100692056
uniprot id: I3K218
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

8128:pld4
gene id: 8128:pld4
uniprot id: A0A669CM65
names: Similarity
messages: Belongs to the phospholipase D family.

8128:LOC100700083
gene id: 8128:LOC100700083
uniprot id: B6E947
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:tmem86a
gene id: 8128:tmem86a
uniprot id: A0A669DV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

8128:LOC100710332
gene id: 8128:LOC100710332
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:ppm1b
gene id: 8128:ppm1b
uniprot id: I3IX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8128:LOC100691161
gene id: 8128:LOC100691161
uniprot id: I3JH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8128:tyk2
gene id: 8128:tyk2
uniprot id: A0A669CVA8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

8128:acer2
gene id: 8128:acer2
uniprot id: I3KAY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:acat1
gene id: 8128:acat1
uniprot id: A0A669CA51
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8128:LOC102077860
gene id: 8128:LOC102077860
uniprot id: I3K494
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:ghitm
gene id: 8128:ghitm
uniprot id: A0A669EUD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8128:lgsn
gene id: 8128:lgsn
uniprot id: I3IUB1
names: Similarity
messages: Belongs to the glutamine synthetase family.

8128:LOC100690576
gene id: 8128:LOC100690576
uniprot id: A0A669EF39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
messages: cytoskeleton

8128:LOC100704436
gene id: 8128:LOC100704436
uniprot id: I3KZN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:gfap
gene id: 8128:gfap
uniprot id: A0A669DXK6
names: Similarity
messages: Belongs to the intermediate filament family.

8128:jak1
gene id: 8128:jak1
uniprot id: A0A669BI32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

8128:pde1b
gene id: 8128:pde1b
uniprot id: I3JCG8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100698550
gene id: 8128:LOC100698550
uniprot id: A0A669F7W1
names: Subcellular Location Annotation
messages: Nucleus

8128:gba
gene id: 8128:gba
uniprot id: A0A669DVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

8128:srpx2
gene id: 8128:srpx2
uniprot id: A0A669BXU5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:adssl1
gene id: 8128:adssl1
uniprot id: I3K2F0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8128:ssr3
gene id: 8128:ssr3
uniprot id: I3JDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

8128:LOC100692852
gene id: 8128:LOC100692852
uniprot id: I3KXC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:hspa14
gene id: 8128:hspa14
uniprot id: I3K9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

8128:pex10
gene id: 8128:pex10
uniprot id: I3KNB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

8128:LOC100695758
gene id: 8128:LOC100695758
uniprot id: A0A669ETZ1
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:polr2h
gene id: 8128:polr2h
uniprot id: A0A669DF46
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

8128:frk
gene id: 8128:frk
uniprot id: I3JZI4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:mrpl19
gene id: 8128:mrpl19
uniprot id: I3KBQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

8128:spi1
gene id: 8128:spi1
uniprot id: I3J491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC100691077
gene id: 8128:LOC100691077
uniprot id: I3IYW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:exoc7
gene id: 8128:exoc7
uniprot id: A0A669E569
uniprot id: I3KNS9
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

8128:sdr16c5
gene id: 8128:sdr16c5
uniprot id: A0A669B714
uniprot id: I3JGG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:rab32
gene id: 8128:rab32
uniprot id: I3K6W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8128:LOC100710349
gene id: 8128:LOC100710349
uniprot id: I3JGB6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8128:LOC100701911
gene id: 8128:LOC100701911
uniprot id: I3JTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100702300
gene id: 8128:LOC100702300
uniprot id: A0A669DW72
names: Subcellular Location Annotation
messages: Membrane

8128:jag1
gene id: 8128:jag1
uniprot id: I3JUT0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8128:LOC100710343
gene id: 8128:LOC100710343
uniprot id: A0A669B2J3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:pank4
gene id: 8128:pank4
uniprot id: I3IVW2
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

8128:LOC100696048
gene id: 8128:LOC100696048
uniprot id: I3JW89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

8128:LOC109201892
gene id: 8128:LOC109201892
uniprot id: A0A669EA63
names: Similarity
messages: Belongs to the globin family.

8128:rflnb
gene id: 8128:rflnb
uniprot id: A0A669AY68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8128:LOC100709332
gene id: 8128:LOC100709332
uniprot id: I3J2E3
uniprot id: I3J2E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

8128:ap4s1
gene id: 8128:ap4s1
uniprot id: A0A669CB92
uniprot id: I3J0I2
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

8128:chd4
gene id: 8128:chd4
uniprot id: I3K597
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8128:LOC102078816
gene id: 8128:LOC102078816
uniprot id: I3JIM9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100711757
gene id: 8128:LOC100711757
uniprot id: I3JLB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

8128:LOC100709416
gene id: 8128:LOC100709416
uniprot id: I3JMY8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100697498
gene id: 8128:LOC100697498
uniprot id: I3KGP0
names: Similarity
messages: Belongs to the PPase family.

8128:LOC100697094
gene id: 8128:LOC100697094
uniprot id: I3K7W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8128:trmt61a
gene id: 8128:trmt61a
uniprot id: A0A669DQS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

8128:LOC102083298
gene id: 8128:LOC102083298
uniprot id: I3K5S1
names: Similarity
messages: Belongs to the apolipoprotein L family.

8128:LOC100698894
gene id: 8128:LOC100698894
uniprot id: A0A669BBR7
uniprot id: A0A669C5D6
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8128:LOC100710178
gene id: 8128:LOC100710178
uniprot id: A0A669AXR3
uniprot id: A0A669BQH0
uniprot id: A0A669E8U9
uniprot id: A0A669ER78
uniprot id: I3KE27
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:thrap3
gene id: 8128:thrap3
uniprot id: I3K7V8
uniprot id: I3K7V9
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

8128:med6
gene id: 8128:med6
uniprot id: A0A669F1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:stard13
gene id: 8128:stard13
uniprot id: A0A669E6T7
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100700965
gene id: 8128:LOC100700965
uniprot id: A0A669AVB0
names: Similarity
messages: Belongs to the DSH family.

8128:LOC100712211
gene id: 8128:LOC100712211
uniprot id: I3JD10
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100695795
gene id: 8128:LOC100695795
uniprot id: I3KUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

8128:ubp1
gene id: 8128:ubp1
uniprot id: I3J208
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

8128:nt5c2
gene id: 8128:nt5c2
uniprot id: I3KRG2
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

8128:dpcd
gene id: 8128:dpcd
uniprot id: I3KRE9
names: Similarity
messages: Belongs to the DPCD family.

8128:LOC100704054
gene id: 8128:LOC100704054
uniprot id: A0A669DNN1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:ikbkb
gene id: 8128:ikbkb
uniprot id: I3KAB1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:qsox1
gene id: 8128:qsox1
uniprot id: I3J0L8
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

8128:smpdl3b
gene id: 8128:smpdl3b
uniprot id: I3KH04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

8128:oxct1
gene id: 8128:oxct1
uniprot id: A0A669CZI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

8128:ankzf1
gene id: 8128:ankzf1
uniprot id: I3JR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

8128:dynlt1
gene id: 8128:dynlt1
uniprot id: I3K6L2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8128:swi5
gene id: 8128:swi5
uniprot id: A0A669BTQ7
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

8128:LOC109194519
gene id: 8128:LOC109194519
uniprot id: A0A669C5L9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:fto
gene id: 8128:fto
uniprot id: A0A669D0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

8128:olfm2
gene id: 8128:olfm2
uniprot id: A0A669ERK4
uniprot id: I3IUH3
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8128:orai1
gene id: 8128:orai1
uniprot id: A0A669BBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8128:LOC100692380
gene id: 8128:LOC100692380
uniprot id: I3KEC8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100691072
gene id: 8128:LOC100691072
uniprot id: I3JD52
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

8128:LOC100695880
gene id: 8128:LOC100695880
uniprot id: I3IU91
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100701020
gene id: 8128:LOC100701020
uniprot id: A0A669E0R0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:mtmr7
gene id: 8128:mtmr7
uniprot id: A0A669EN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8128:zc3h14
gene id: 8128:zc3h14
uniprot id: I3KDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

8128:sec22c
gene id: 8128:sec22c
uniprot id: A0A669D3V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

8128:LOC100704607
gene id: 8128:LOC100704607
uniprot id: I3K034
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:LOC100698410
gene id: 8128:LOC100698410
uniprot id: A0A669BE49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

8128:mars2
gene id: 8128:mars2
uniprot id: A0A669EYR4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8128:cldn1
gene id: 8128:cldn1
uniprot id: A0A669AY50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100701884
gene id: 8128:LOC100701884
uniprot id: A0A669D8Z7
uniprot id: A0A669EC05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:ppp1r21
gene id: 8128:ppp1r21
uniprot id: I3JU35
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8128:LOC100702483
gene id: 8128:LOC100702483
uniprot id: I3KKG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:grk6
gene id: 8128:grk6
uniprot id: A0A669CP56
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8128:LOC100700067
gene id: 8128:LOC100700067
uniprot id: A0A669AVX0
names: Subcellular Location Annotation
messages: Membrane

8128:pth1r
gene id: 8128:pth1r
uniprot id: I3JSP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8128:LOC100708232
gene id: 8128:LOC100708232
uniprot id: A0A669DJV9
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100711672
gene id: 8128:LOC100711672
uniprot id: A0A669BXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8128:hs3st5
gene id: 8128:hs3st5
uniprot id: I3JZI9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC102079812
gene id: 8128:LOC102079812
uniprot id: A0A669C5E6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:ankrd34a
gene id: 8128:ankrd34a
uniprot id: I3KYR0
names: Similarity
messages: Belongs to the ANKRD34 family.

8128:LOC100698390
gene id: 8128:LOC100698390
uniprot id: I3K189
uniprot id: I3K190
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

8128:vasp
gene id: 8128:vasp
uniprot id: A0A669ECZ1
uniprot id: I3JD55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

8128:cstf1
gene id: 8128:cstf1
uniprot id: I3J5B2
names: Subcellular Location Annotation
messages: Nucleus

8128:capn3
gene id: 8128:capn3
uniprot id: I3IV72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.

8128:tp53i11
gene id: 8128:tp53i11
uniprot id: I3JP49
names: Subcellular Location Annotation
messages: Membrane

8128:sumf2
gene id: 8128:sumf2
uniprot id: A0A669D1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

8128:LOC100690935
gene id: 8128:LOC100690935
uniprot id: A0A669CAW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8128:sec63
gene id: 8128:sec63
uniprot id: A0A669BUM6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100700355
gene id: 8128:LOC100700355
uniprot id: I3JSG3
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8128:LOC100696907
gene id: 8128:LOC100696907
uniprot id: I3KQ86
names: Subcellular Location Annotation
messages: Membrane

8128:LOC109197411
gene id: 8128:LOC109197411
uniprot id: A0A669CFV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100691730
gene id: 8128:LOC100691730
uniprot id: A0A669EF87
uniprot id: I3J9P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8128:LOC102079774
gene id: 8128:LOC102079774
uniprot id: A0A669C5Q5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

8128:mrpl22
gene id: 8128:mrpl22
uniprot id: I3KHV8
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

8128:LOC100704168
gene id: 8128:LOC100704168
uniprot id: A0A669F4B0
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8128:iqsec3
gene id: 8128:iqsec3
uniprot id: A0A669D6Z7
names: Similarity
messages: Belongs to the BRAG family.

8128:LOC100691465
gene id: 8128:LOC100691465
uniprot id: I3KSB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNTX/VTX toxin family.
messages: Secreted

8128:plk2
gene id: 8128:plk2
uniprot id: I3KCZ2
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

8128:LOC100702846
gene id: 8128:LOC100702846
uniprot id: A0A669CYS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8128:rheb
gene id: 8128:rheb
uniprot id: A0A669BI50
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:LOC100693905
gene id: 8128:LOC100693905
uniprot id: A0A669ESF0
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

8128:iapp
gene id: 8128:iapp
uniprot id: A0A669CPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
messages: Secreted

8128:LOC100710479
gene id: 8128:LOC100710479
uniprot id: I3KHS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

8128:syne3
gene id: 8128:syne3
uniprot id: I3JR94
names: Similarity
messages: Belongs to the nesprin family.

8128:rara
gene id: 8128:rara
uniprot id: I3KVD6
uniprot id: I3KVD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8128:arx
gene id: 8128:arx
uniprot id: A0A669EE40
names: Subcellular Location Annotation
messages: Nucleus

8128:tvp23a
gene id: 8128:tvp23a
uniprot id: I3KBC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

8128:LOC100705495
gene id: 8128:LOC100705495
uniprot id: A0A669CJC2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100705418
gene id: 8128:LOC100705418
uniprot id: A0A669C9P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100709470
gene id: 8128:LOC100709470
uniprot id: I3KMR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100708447
gene id: 8128:LOC100708447
uniprot id: I3JGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

8128:g6pc
gene id: 8128:g6pc
uniprot id: I3KPG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8128:LOC100696550
gene id: 8128:LOC100696550
uniprot id: I3J1T5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:wwox
gene id: 8128:wwox
uniprot id: A0A669DQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Golgi apparatus
messages: Lysosome
messages: Mitochondrion

8128:LOC100698360
gene id: 8128:LOC100698360
uniprot id: I3KPJ9
names: Similarity
messages: Belongs to the pleurocidin family.

8128:mttp
gene id: 8128:mttp
uniprot id: I3KAW4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100691194
gene id: 8128:LOC100691194
uniprot id: A0A669F4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8128:KEH09 p01
gene id: 8128:KEH09_p01
uniprot id: D2KP36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC102082028
gene id: 8128:LOC102082028
uniprot id: I3JTF1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100696391
gene id: 8128:LOC100696391
uniprot id: A0A669E3S5
names: Similarity
messages: Belongs to the RUTBC family.

8128:paqr8
gene id: 8128:paqr8
uniprot id: I3KYM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8128:LOC100703084
gene id: 8128:LOC100703084
uniprot id: A0A669CRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

8128:ythdc1
gene id: 8128:ythdc1
uniprot id: I3K475
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

8128:psme2
gene id: 8128:psme2
uniprot id: I3JHK6
names: Similarity
messages: Belongs to the PA28 family.

8128:LOC100707119
gene id: 8128:LOC100707119
uniprot id: I3KNE8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100703179
gene id: 8128:LOC100703179
uniprot id: I3J859
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8128:gsr
gene id: 8128:gsr
uniprot id: I3J289
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

8128:LOC100703351
gene id: 8128:LOC100703351
uniprot id: I3J8N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8128:six3
gene id: 8128:six3
uniprot id: I3IX46
names: Subcellular Location Annotation
messages: Nucleus

8128:gpr4
gene id: 8128:gpr4
uniprot id: A0A669ET06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100711404
gene id: 8128:LOC100711404
uniprot id: A0A669D183
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

8128:slc2a5
gene id: 8128:slc2a5
uniprot id: A0A669F0E0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8128:LOC100705146
gene id: 8128:LOC100705146
uniprot id: A0A669B450
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

8128:LOC102079422
gene id: 8128:LOC102079422
uniprot id: I3JXR0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:g2e3
gene id: 8128:g2e3
uniprot id: I3J0C6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100705376
gene id: 8128:LOC100705376
uniprot id: I3J3B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8128:foxi2
gene id: 8128:foxi2
uniprot id: I3KG76
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100710321
gene id: 8128:LOC100710321
uniprot id: I3JR54
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100696340
gene id: 8128:LOC100696340
uniprot id: A0A669FB63
names: Similarity
messages: Belongs to the nucleobindin family.

8128:lin9
gene id: 8128:lin9
uniprot id: I3K758
names: Similarity
messages: Belongs to the lin-9 family.

8128:kdr
gene id: 8128:kdr
uniprot id: I3J4B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100698562
gene id: 8128:LOC100698562
uniprot id: I3J0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:ndufs3
gene id: 8128:ndufs3
uniprot id: I3JIT2
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

8128:LOC100694427
gene id: 8128:LOC100694427
uniprot id: A0A669DZ50
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:mrpl32
gene id: 8128:mrpl32
uniprot id: A0A669AVT1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

8128:LOC102077594
gene id: 8128:LOC102077594
uniprot id: A0A669B7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:fzd8
gene id: 8128:fzd8
uniprot id: I3KXV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8128:polr2k
gene id: 8128:polr2k
uniprot id: A0A669F840
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

8128:LOC100691671
gene id: 8128:LOC100691671
uniprot id: I3J4B3
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8128:appl2
gene id: 8128:appl2
uniprot id: I3JQ85
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

8128:LOC100704783
gene id: 8128:LOC100704783
uniprot id: I3J6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

8128:LOC100705836
gene id: 8128:LOC100705836
uniprot id: I3IWJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

8128:LOC100707943
gene id: 8128:LOC100707943
uniprot id: A0A669EM83
uniprot id: I3KBS2
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8128:LOC100690390
gene id: 8128:LOC100690390
uniprot id: I3JHB0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:tnfrsf21
gene id: 8128:tnfrsf21
uniprot id: I3JGZ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100690442
gene id: 8128:LOC100690442
uniprot id: I3K5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8128:htr1a
gene id: 8128:htr1a
uniprot id: I3KYV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:ncor2
gene id: 8128:ncor2
uniprot id: I3JY88
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

8128:ppp2r5d
gene id: 8128:ppp2r5d
uniprot id: I3JJB6
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8128:LOC100704596
gene id: 8128:LOC100704596
uniprot id: I3KH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

8128:nudt2
gene id: 8128:nudt2
uniprot id: I3KX39
names: Similarity
messages: Belongs to the Nudix hydrolase family.

8128:LOC100697822
gene id: 8128:LOC100697822
uniprot id: I3IVR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

8128:gabrb3
gene id: 8128:gabrb3
uniprot id: I3KTA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:nup205
gene id: 8128:nup205
uniprot id: I3JVV0
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

8128:nr0b1
gene id: 8128:nr0b1
uniprot id: Q8AY13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8128:pcnx2
gene id: 8128:pcnx2
uniprot id: I3IWN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

8128:LOC100706082
gene id: 8128:LOC100706082
uniprot id: I3KVZ9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8128:LOC100694690
gene id: 8128:LOC100694690
uniprot id: I3KD73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:LOC102079122
gene id: 8128:LOC102079122
uniprot id: A0A669E8V0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8128:lg22h18orf21
gene id: 8128:lg22h18orf21
uniprot id: A0A669AZZ2
names: Similarity
messages: Belongs to the UPF0711 family.

8128:LOC100701870
gene id: 8128:LOC100701870
uniprot id: I3KF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8128:LOC100694062
gene id: 8128:LOC100694062
uniprot id: A0A669BTV6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102077656
gene id: 8128:LOC102077656
uniprot id: I3KZJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

8128:LOC100697106
gene id: 8128:LOC100697106
uniprot id: I3KVV2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8128:ppia
gene id: 8128:ppia
uniprot id: I3K035
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:LOC100696817
gene id: 8128:LOC100696817
uniprot id: I3JAM0
names: Similarity
messages: Belongs to the perilipin family.

8128:ccnd1
gene id: 8128:ccnd1
uniprot id: A0A669DBR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:LOC100695499
gene id: 8128:LOC100695499
uniprot id: I3JAH0
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100712280
gene id: 8128:LOC100712280
uniprot id: A0A669CLZ2
uniprot id: I3KBX9
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8128:LOC102083261
gene id: 8128:LOC102083261
uniprot id: I3J6G3
names: Similarity
messages: Belongs to the HEBP family.

8128:prdm4
gene id: 8128:prdm4
uniprot id: I3KIX3
names: Subcellular Location Annotation
messages: Nucleus

8128:fgf20b
gene id: 8128:fgf20b
uniprot id: H2E8V7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:hsd17b10
gene id: 8128:hsd17b10
uniprot id: A0A669B5T4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:ets1
gene id: 8128:ets1
uniprot id: A0A669BP67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:mpp3
gene id: 8128:mpp3
uniprot id: A0A669BSJ4
uniprot id: A0A669CA61
uniprot id: I3IWR2
names: Similarity
messages: Belongs to the MAGUK family.

8128:raly
gene id: 8128:raly
uniprot id: I3J9M1
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

8128:LOC100693678
gene id: 8128:LOC100693678
uniprot id: A0A669CAP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8128:LOC100707642
gene id: 8128:LOC100707642
uniprot id: A0A669EQ56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:got1
gene id: 8128:got1
uniprot id: A0A669C4C3
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

8128:LOC100706613
gene id: 8128:LOC100706613
uniprot id: I3IXV9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696844
gene id: 8128:LOC100696844
uniprot id: I3JWJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100692674
gene id: 8128:LOC100692674
uniprot id: I3KVG2
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8128:fam19a5
gene id: 8128:fam19a5
uniprot id: A0A669EYK0
names: Similarity
messages: Belongs to the TAFA family.

8128:gk5
gene id: 8128:gk5
uniprot id: A0A669DCY2
names: Similarity
messages: Belongs to the FGGY kinase family.

8128:LOC100703099
gene id: 8128:LOC100703099
uniprot id: I3KAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100702316
gene id: 8128:LOC100702316
uniprot id: A0A669CG38
uniprot id: A0A669CHQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8128:LOC102078622
gene id: 8128:LOC102078622
uniprot id: A0A669BUQ7
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100691636
gene id: 8128:LOC100691636
uniprot id: I3KRC0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100699015
gene id: 8128:LOC100699015
uniprot id: I3IZ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

8128:fyttd1
gene id: 8128:fyttd1
uniprot id: I3JX78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle
messages: nucleoplasm

8128:foxn4
gene id: 8128:foxn4
uniprot id: I3K785
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100690330
gene id: 8128:LOC100690330
uniprot id: I3K166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:nek7
gene id: 8128:nek7
uniprot id: A0A669DW94
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:znf598
gene id: 8128:znf598
uniprot id: I3KF11
names: Similarity
messages: Belongs to the ZNF598/HEL2 family.

8128:LOC100694804
gene id: 8128:LOC100694804
uniprot id: A0A669BFH7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC102079772
gene id: 8128:LOC102079772
uniprot id: A0A669ECR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

8128:LOC100695806
gene id: 8128:LOC100695806
uniprot id: A0A669E264
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:bbs10
gene id: 8128:bbs10
uniprot id: I3KCZ4
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

8128:LOC109201897
gene id: 8128:LOC109201897
uniprot id: A0A669C646
names: Similarity
messages: Belongs to the globin family.

8128:LOC100693756
gene id: 8128:LOC100693756
uniprot id: A0A669BMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8128:nfil3
gene id: 8128:nfil3
uniprot id: I3KZR3
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8128:acadsb
gene id: 8128:acadsb
uniprot id: A0A669FCE4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8128:ccnc
gene id: 8128:ccnc
uniprot id: A0A669E6H2
names: Similarity
messages: Belongs to the cyclin family.

8128:LOC100710470
gene id: 8128:LOC100710470
uniprot id: A0A669E7D5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100702332
gene id: 8128:LOC100702332
uniprot id: A0A669CRM4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100698817
gene id: 8128:LOC100698817
uniprot id: A0A669CUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:LOC100708531
gene id: 8128:LOC100708531
uniprot id: I3JPF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8128:LOC100699905
gene id: 8128:LOC100699905
uniprot id: A0A669D885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8128:LOC100708334
gene id: 8128:LOC100708334
uniprot id: I3JTJ1
names: Similarity
messages: Belongs to the FAM83 family.

8128:fam120a
gene id: 8128:fam120a
uniprot id: I3J5B5
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

8128:LOC100693661
gene id: 8128:LOC100693661
uniprot id: I3KXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:rnaseh2b
gene id: 8128:rnaseh2b
uniprot id: I3JHR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

8128:hyou1
gene id: 8128:hyou1
uniprot id: A0A669BHA9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:LOC100696990
gene id: 8128:LOC100696990
uniprot id: A0A669E628
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:ypel1
gene id: 8128:ypel1
uniprot id: I3K9E6
names: Similarity
messages: Belongs to the yippee family.

8128:LOC100698873
gene id: 8128:LOC100698873
uniprot id: A0A669CIB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8128:LOC102077017
gene id: 8128:LOC102077017
uniprot id: I3J0Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

8128:LOC100691504
gene id: 8128:LOC100691504
uniprot id: I3KL05
names: Similarity
messages: Belongs to the peptidase A1 family.

8128:snupn
gene id: 8128:snupn
uniprot id: I3K4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

8128:sdhaf1
gene id: 8128:sdhaf1
uniprot id: A0A669BU17
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

8128:pkp4
gene id: 8128:pkp4
uniprot id: A0A669CC84
uniprot id: A0A669DRH1
names: Similarity
messages: Belongs to the beta-catenin family.

8128:LOC100703489
gene id: 8128:LOC100703489
uniprot id: A0A669DLG7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:tbc1d31
gene id: 8128:tbc1d31
uniprot id: A0A669EN09
names: Function
names: Subcellular Location Annotation
messages: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
messages: centriolar satellite
messages: cilium basal body

8128:LOC100699665
gene id: 8128:LOC100699665
uniprot id: I3KQS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8128:LOC100698754
gene id: 8128:LOC100698754
uniprot id: A0A669C233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8128:LOC102082825
gene id: 8128:LOC102082825
uniprot id: I3K5A3
names: Similarity
messages: Belongs to the Niban family.

8128:gpr119
gene id: 8128:gpr119
uniprot id: I3K6B0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:tmem39a
gene id: 8128:tmem39a
uniprot id: I3J5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

8128:mvd
gene id: 8128:mvd
uniprot id: A0A669CV21
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

8128:LOC100705273
gene id: 8128:LOC100705273
uniprot id: A0A669ESY9
names: Similarity
messages: Belongs to the MDFI family.

8128:glra2
gene id: 8128:glra2
uniprot id: I3KGF2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8128:napepld
gene id: 8128:napepld
uniprot id: I3K0U8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPE-PLD family.
messages: Binds 2 zinc divalent cations per subunit.
messages: Homodimer. Bile acids promote the assembly of inactive monomers into an active dimer and enable catalysis.
messages: Nucleus envelope

8128:LOC100699370
gene id: 8128:LOC100699370
uniprot id: I3JDU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100693456
gene id: 8128:LOC100693456
uniprot id: A0A669B5L1
names: Similarity
messages: Belongs to the TTC39 family.

8128:lrp12
gene id: 8128:lrp12
uniprot id: A0A669EQG3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC109202854
gene id: 8128:LOC109202854
uniprot id: A0A669CU47
names: Similarity
messages: Belongs to the asteroid family.

8128:ddx47
gene id: 8128:ddx47
uniprot id: A0A669CGF6
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

8128:ebna1bp2
gene id: 8128:ebna1bp2
uniprot id: A0A669E9N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: Required for the processing of the 27S pre-rRNA.
messages: nucleolus

8128:cnksr1
gene id: 8128:cnksr1
uniprot id: I3J6C5
names: Similarity
messages: Belongs to the CNKSR family.

8128:LOC100690084
gene id: 8128:LOC100690084
uniprot id: A0A669BPY4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100701136
gene id: 8128:LOC100701136
uniprot id: I3K9J1
names: Similarity
messages: Belongs to the IFI44 family.

8128:sfrp2
gene id: 8128:sfrp2
uniprot id: I3JVD2
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100701826
gene id: 8128:LOC100701826
uniprot id: I3KZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:tmem59l
gene id: 8128:tmem59l
uniprot id: A0A669EX24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:coq6
gene id: 8128:coq6
uniprot id: I3KWA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

8128:LOC100706941
gene id: 8128:LOC100706941
uniprot id: I3KHJ4
names: Subcellular Location Annotation
messages: Membrane

8128:suz12
gene id: 8128:suz12
uniprot id: I3KNV3
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

8128:akirin1
gene id: 8128:akirin1
uniprot id: A0A669CDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8128:slbp
gene id: 8128:slbp
uniprot id: A0A669DYW5
names: Similarity
messages: Belongs to the SLBP family.

8128:tbxa2r
gene id: 8128:tbxa2r
uniprot id: A0A669DTT4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100694765
gene id: 8128:LOC100694765
uniprot id: I3IYQ8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:sec16a
gene id: 8128:sec16a
uniprot id: A0A669E3S7
uniprot id: I3JKN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

8128:trnt1
gene id: 8128:trnt1
uniprot id: I3KWP8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

8128:tbp
gene id: 8128:tbp
uniprot id: A0A669F7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

8128:LOC100705706
gene id: 8128:LOC100705706
uniprot id: I3K3Z9
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:LOC100704979
gene id: 8128:LOC100704979
uniprot id: I3JGI1
names: Similarity
messages: Belongs to the S-100 family.

8128:LOC100699493
gene id: 8128:LOC100699493
uniprot id: A0A669E9P1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

8128:LOC100700431
gene id: 8128:LOC100700431
uniprot id: A0A669EH34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

8128:LOC100702095
gene id: 8128:LOC100702095
uniprot id: A0A669DYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100706717
gene id: 8128:LOC100706717
uniprot id: A0A669E7P6
names: Subcellular Location Annotation
messages: Membrane

8128:rif1
gene id: 8128:rif1
uniprot id: A0A669B4W5
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

8128:LOC100699319
gene id: 8128:LOC100699319
uniprot id: I3J1C6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:abi1
gene id: 8128:abi1
uniprot id: A0A669B498
uniprot id: A0A669BJZ6
uniprot id: A0A669E8W8
uniprot id: I3JGS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8128:lipt2
gene id: 8128:lipt2
uniprot id: A0A669ERR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Mitochondrion

8128:nbn
gene id: 8128:nbn
uniprot id: I3JG26
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

8128:LOC100703630
gene id: 8128:LOC100703630
uniprot id: I3KFF3
names: Subcellular Location Annotation
messages: Membrane

8128:lg17h8orf82
gene id: 8128:lg17h8orf82
uniprot id: I3KTS8
names: Similarity
messages: Belongs to the UPF0598 family.

8128:LOC100707081
gene id: 8128:LOC100707081
uniprot id: I3KU56
names: Similarity
messages: Belongs to the DeSI family.

8128:tmem206
gene id: 8128:tmem206
uniprot id: I3IV95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

8128:wnt9a
gene id: 8128:wnt9a
uniprot id: A0A669BVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:LOC100691285
gene id: 8128:LOC100691285
uniprot id: I3KQ97
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

8128:vti1b
gene id: 8128:vti1b
uniprot id: I3KUB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

8128:LOC100710579
gene id: 8128:LOC100710579
uniprot id: A0A669C2R6
uniprot id: A0A669DJ08
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8128:LOC100705528
gene id: 8128:LOC100705528
uniprot id: A0A669F5T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

8128:creg1
gene id: 8128:creg1
uniprot id: A0A669EQS3
uniprot id: I3JR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Chromosome
messages: Secreted

8128:LOC100705065
gene id: 8128:LOC100705065
uniprot id: I3JB75
names: Similarity
messages: Belongs to the splicing factor SR family.

8128:yeats4
gene id: 8128:yeats4
uniprot id: I3K0U5
names: Subcellular Location Annotation
messages: Nucleus

8128:galnt17
gene id: 8128:galnt17
uniprot id: I3JEU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:gpr161
gene id: 8128:gpr161
uniprot id: I3K9Z7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100534480
gene id: 8128:LOC100534480
uniprot id: I3KCJ8
names: Subcellular Location Annotation
messages: Nucleus

8128:tmem233
gene id: 8128:tmem233
uniprot id: A0A669CE34
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8128:toe1
gene id: 8128:toe1
uniprot id: A0A669BXB5
names: Similarity
messages: Belongs to the CAF1 family.

8128:grina
gene id: 8128:grina
uniprot id: I3J2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8128:LOC100711031
gene id: 8128:LOC100711031
uniprot id: A0A669EF67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8128:hsp90b1
gene id: 8128:hsp90b1
uniprot id: A0A669BCF4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8128:LOC100708116
gene id: 8128:LOC100708116
uniprot id: I3J6Y0
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:ddx4
gene id: 8128:ddx4
uniprot id: Q8QHL6
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:cfap299
gene id: 8128:cfap299
uniprot id: A0A669DIC2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

8128:LOC100707815
gene id: 8128:LOC100707815
uniprot id: A0A669CJ29
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:LOC100690639
gene id: 8128:LOC100690639
uniprot id: I3JNH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

8128:LOC100695819
gene id: 8128:LOC100695819
uniprot id: A0A669ESH6
names: Subcellular Location Annotation
messages: Membrane

8128:kansl2
gene id: 8128:kansl2
uniprot id: I3KI70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

8128:mrpl30
gene id: 8128:mrpl30
uniprot id: A0A669B374
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

8128:pign
gene id: 8128:pign
uniprot id: I3KAT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

8128:kcnk5
gene id: 8128:kcnk5
uniprot id: I3KU36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:bud23
gene id: 8128:bud23
uniprot id: I3J7E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100700137
gene id: 8128:LOC100700137
uniprot id: A0A669EUQ9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100691835
gene id: 8128:LOC100691835
uniprot id: I3KAV8
names: Subcellular Location Annotation
messages: Secreted

8128:stk11ip
gene id: 8128:stk11ip
uniprot id: I3K6P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

8128:LOC100703436
gene id: 8128:LOC100703436
uniprot id: A0A669E8F3
uniprot id: I3KDE0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

8128:LOC100699921
gene id: 8128:LOC100699921
uniprot id: A0A669BNC8
names: Similarity
messages: Belongs to the complex I LYR family.

8128:sec61a1
gene id: 8128:sec61a1
uniprot id: A0A669EGQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The SEC61 channel-forming translocon complex consists of channel-forming core components SEC61A1, SEC61B and SEC61G and different auxiliary components such as SEC62 and SEC63 (By similarity). The SEC61 channel associates with the multi-pass translocon (MPT) complex.

8128:kcnh4
gene id: 8128:kcnh4
uniprot id: I3IXS4
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8128:rrp12
gene id: 8128:rrp12
uniprot id: I3JSX8
names: Similarity
messages: Belongs to the RRP12 family.

8128:LOC109202892
gene id: 8128:LOC109202892
uniprot id: A0A669ET21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8128:LOC100703370
gene id: 8128:LOC100703370
uniprot id: A0A669CDB3
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:unc5c
gene id: 8128:unc5c
uniprot id: A0A669DEM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8128:ddx51
gene id: 8128:ddx51
uniprot id: I3IZK1
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8128:snta1
gene id: 8128:snta1
uniprot id: I3JI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

8128:LOC102080564
gene id: 8128:LOC102080564
uniprot id: A0A669E183
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8128:eif3l
gene id: 8128:eif3l
uniprot id: A0A669EEW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8128:cuedc2
gene id: 8128:cuedc2
uniprot id: I3KQ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

8128:comt
gene id: 8128:comt
uniprot id: I3KWR6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

8128:fshb
gene id: 8128:fshb
uniprot id: Q7T2Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8128:LOC100701052
gene id: 8128:LOC100701052
uniprot id: I3IUN0
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

8128:LOC100701802
gene id: 8128:LOC100701802
uniprot id: I3KCA8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:treh
gene id: 8128:treh
uniprot id: I3JEG0
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

8128:kpna6
gene id: 8128:kpna6
uniprot id: I3JLH4
names: Similarity
messages: Belongs to the importin alpha family.

8128:LOC100707074
gene id: 8128:LOC100707074
uniprot id: A0A669ET61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8128:dync1h1
gene id: 8128:dync1h1
uniprot id: I3JBA9
uniprot id: I3JBB0
names: Similarity
messages: Belongs to the dynein heavy chain family.

8128:LOC100708834
gene id: 8128:LOC100708834
uniprot id: I3KJM5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100700216
gene id: 8128:LOC100700216
uniprot id: I3KQB1
names: Similarity
messages: Belongs to the PPase family.

8128:LOC100697282
gene id: 8128:LOC100697282
uniprot id: A0A669BKW8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710605
gene id: 8128:LOC100710605
uniprot id: A0A669CCQ6
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

8128:selenoo
gene id: 8128:selenoo
uniprot id: I3JW73
names: Similarity
messages: Belongs to the SELO family.

8128:LOC100691116
gene id: 8128:LOC100691116
uniprot id: A0A669BDX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100704278
gene id: 8128:LOC100704278
uniprot id: I3JTA8
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC102076824
gene id: 8128:LOC102076824
uniprot id: A0A669BYR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100711822
gene id: 8128:LOC100711822
uniprot id: I3JF18
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:pkp2
gene id: 8128:pkp2
uniprot id: A0A669ENL3
names: Similarity
messages: Belongs to the beta-catenin family.

8128:LOC100692868
gene id: 8128:LOC100692868
uniprot id: A0A669BFG4
uniprot id: A0A669DRK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100697028
gene id: 8128:LOC100697028
uniprot id: I3J8N1
names: Similarity
messages: Belongs to the serpin family.

8128:LOC100712203
gene id: 8128:LOC100712203
uniprot id: I3KZT0
names: Subcellular Location Annotation
messages: Cytoplasm

8128:noc2l
gene id: 8128:noc2l
uniprot id: I3J2B3
names: Similarity
messages: Belongs to the NOC2 family.

8128:LOC100701285
gene id: 8128:LOC100701285
uniprot id: A0A669AV24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100711454
gene id: 8128:LOC100711454
uniprot id: I3JT09
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC100534415
gene id: 8128:LOC100534415
uniprot id: A0A669D429
uniprot id: I3ITW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8128:LOC100712029
gene id: 8128:LOC100712029
uniprot id: I3K592
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:LOC100690406
gene id: 8128:LOC100690406
uniprot id: I3KYV7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:psmb8
gene id: 8128:psmb8
uniprot id: I3KVV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8128:LOC100706889
gene id: 8128:LOC100706889
uniprot id: A0A669C6T9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

8128:hyi
gene id: 8128:hyi
uniprot id: I3JJX4
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

8128:prmt7
gene id: 8128:prmt7
uniprot id: A0A669ELB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

8128:sar1a
gene id: 8128:sar1a
uniprot id: A0A669B6U9
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

8128:ncoa1
gene id: 8128:ncoa1
uniprot id: I3KF92
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

8128:LOC100710250
gene id: 8128:LOC100710250
uniprot id: A0A669DMM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100707493
gene id: 8128:LOC100707493
uniprot id: A0A669CU13
uniprot id: A0A669E3Q9
uniprot id: A0A669F6F6
uniprot id: A0A669F9Q0
uniprot id: I3K1G4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

8128:scrn3
gene id: 8128:scrn3
uniprot id: I3JPS9
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

8128:LOC100704989
gene id: 8128:LOC100704989
uniprot id: I3KQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100700872
gene id: 8128:LOC100700872
uniprot id: I3JMM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8128:mapk6
gene id: 8128:mapk6
uniprot id: I3IUE3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

8128:plpp1
gene id: 8128:plpp1
uniprot id: I3JL34
uniprot id: I3JL35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:LOC100709284
gene id: 8128:LOC100709284
uniprot id: A0A669EDU4
uniprot id: I3JIB7
uniprot id: I3JIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100708987
gene id: 8128:LOC100708987
uniprot id: I3K7D2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8128:pdia6
gene id: 8128:pdia6
uniprot id: A0A669EYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

8128:gdpd1
gene id: 8128:gdpd1
uniprot id: A0A669EWV2
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8128:chmp1b
gene id: 8128:chmp1b
uniprot id: A0A669BVW9
names: Similarity
messages: Belongs to the SNF7 family.

8128:LOC100534423
gene id: 8128:LOC100534423
uniprot id: I3J4C5
names: Subcellular Location Annotation
messages: Nucleus

8128:mrap2
gene id: 8128:mrap2
uniprot id: A0A669DIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:yipf5
gene id: 8128:yipf5
uniprot id: A0A669BM65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

8128:LOC100700220
gene id: 8128:LOC100700220
uniprot id: I3K6P4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC109196270
gene id: 8128:LOC109196270
uniprot id: A0A669DDM4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:zcchc8
gene id: 8128:zcchc8
uniprot id: I3K6E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

8128:LOC100692393
gene id: 8128:LOC100692393
uniprot id: I3IUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8128:tecpr1
gene id: 8128:tecpr1
uniprot id: I3KV08
names: Similarity
messages: Belongs to the TECPR1 family.

8128:hs2st1
gene id: 8128:hs2st1
uniprot id: I3JWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:cux1
gene id: 8128:cux1
uniprot id: I3J7D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100701835
gene id: 8128:LOC100701835
uniprot id: I3K3V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

8128:LOC100703725
gene id: 8128:LOC100703725
uniprot id: I3J881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:eva1c
gene id: 8128:eva1c
uniprot id: I3JAJ4
names: Similarity
messages: Belongs to the EVA1 family.

8128:syt1
gene id: 8128:syt1
uniprot id: I3ITR5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

8128:hoxb3
gene id: 8128:hoxb3
uniprot id: A0A669EQP1
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100691236
gene id: 8128:LOC100691236
uniprot id: Q4VPV2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

8128:igf2bp2
gene id: 8128:igf2bp2
uniprot id: I3JR61
names: Similarity
messages: Belongs to the RRM IMP/VICKZ family.

8128:prrc1
gene id: 8128:prrc1
uniprot id: I3JZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

8128:crybb1
gene id: 8128:crybb1
uniprot id: I3JZQ5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:ddx49
gene id: 8128:ddx49
uniprot id: I3K4H6
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:LOC100703644
gene id: 8128:LOC100703644
uniprot id: I3K9Q3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8128:mrpl35
gene id: 8128:mrpl35
uniprot id: I3KW67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

8128:phox2b
gene id: 8128:phox2b
uniprot id: I3IYN7
names: Subcellular Location Annotation
messages: Nucleus

8128:eci1
gene id: 8128:eci1
uniprot id: A0A669EVV5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8128:nck2
gene id: 8128:nck2
uniprot id: I3K9S8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

8128:LOC100705800
gene id: 8128:LOC100705800
uniprot id: I3J8R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8128:LOC102081663
gene id: 8128:LOC102081663
uniprot id: I3JEE2
names: Similarity
messages: Belongs to the RIPOR family.

8128:LOC100694102
gene id: 8128:LOC100694102
uniprot id: I3KN40
names: Similarity
messages: Belongs to the FAM53 family.

8128:LOC100704166
gene id: 8128:LOC100704166
uniprot id: I3J887
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100700685
gene id: 8128:LOC100700685
uniprot id: A0A669AZX5
uniprot id: I3JGM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

8128:LOC100702337
gene id: 8128:LOC100702337
uniprot id: I3KCN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8128:hmx2
gene id: 8128:hmx2
uniprot id: I3IVN6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100712427
gene id: 8128:LOC100712427
uniprot id: I3K906
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8128:LOC100698045
gene id: 8128:LOC100698045
uniprot id: A0A669B634
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

8128:LOC100710738
gene id: 8128:LOC100710738
uniprot id: I3J140
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100702108
gene id: 8128:LOC100702108
uniprot id: A0A669DZ84
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:itga6
gene id: 8128:itga6
uniprot id: A0A669CI67
uniprot id: I3JQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100690677
gene id: 8128:LOC100690677
uniprot id: A0A669CGB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8128:LOC102077312
gene id: 8128:LOC102077312
uniprot id: I3KH75
names: Similarity
messages: Belongs to the NSG family.

8128:LOC100697642
gene id: 8128:LOC100697642
uniprot id: I3JDH3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8128:LOC100708249
gene id: 8128:LOC100708249
uniprot id: A0A669DUR4
names: Similarity
messages: Belongs to the FAM20 family.

8128:mturn
gene id: 8128:mturn
uniprot id: A0A669BNY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

8128:ppp1r14c
gene id: 8128:ppp1r14c
uniprot id: I3IVJ1
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8128:oxt
gene id: 8128:oxt
uniprot id: I3KDH7
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

8128:LOC100697091
gene id: 8128:LOC100697091
uniprot id: A0A669C684
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8128:rbpj
gene id: 8128:rbpj
uniprot id: A0A669EM66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

8128:nr0b2
gene id: 8128:nr0b2
uniprot id: Q8AUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8128:il10
gene id: 8128:il10
uniprot id: A0A190A823
uniprot id: I3KT29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

8128:LOC100711575
gene id: 8128:LOC100711575
uniprot id: A0A669E9E6
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:sox14
gene id: 8128:sox14
uniprot id: A4GU08
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704827
gene id: 8128:LOC100704827
uniprot id: I3J5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8128:parp1
gene id: 8128:parp1
uniprot id: I3K764
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

8128:taldo1
gene id: 8128:taldo1
uniprot id: I3JEL2
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

8128:aspm
gene id: 8128:aspm
uniprot id: A0A669EJV1
uniprot id: A0A669EUL8
names: Subcellular Location Annotation
messages: Nucleus

8128:rpl10a
gene id: 8128:rpl10a
uniprot id: A0A669CP58
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

8128:LOC100693903
gene id: 8128:LOC100693903
uniprot id: A0A669EQS7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC109200094
gene id: 8128:LOC109200094
uniprot id: A0A669E0U1
names: Similarity
messages: Belongs to the HARBI1 family.

8128:LOC100707873
gene id: 8128:LOC100707873
uniprot id: A0A669C8E0
uniprot id: I3KEA2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

8128:LOC100534494
gene id: 8128:LOC100534494
uniprot id: I3KQC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

8128:pus7
gene id: 8128:pus7
uniprot id: A0A669CAB0
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

8128:tbx20
gene id: 8128:tbx20
uniprot id: I3JHH5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC100708222
gene id: 8128:LOC100708222
uniprot id: I3JZD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC109194230
gene id: 8128:LOC109194230
uniprot id: A0A669CUU4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:LOC100693193
gene id: 8128:LOC100693193
uniprot id: I3KK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

8128:fdps
gene id: 8128:fdps
uniprot id: I3JGK5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8128:eya2
gene id: 8128:eya2
uniprot id: I3JIC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

8128:dut
gene id: 8128:dut
uniprot id: I3K6Q1
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

8128:LOC100690652
gene id: 8128:LOC100690652
uniprot id: A0A669C4B0
uniprot id: A0A669DMP0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

8128:LOC100709693
gene id: 8128:LOC100709693
uniprot id: A0A669B4T3
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8128:LOC100707664
gene id: 8128:LOC100707664
uniprot id: A0A669BFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Early endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

8128:med10
gene id: 8128:med10
uniprot id: I3JLM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8128:mtmr2
gene id: 8128:mtmr2
uniprot id: A0A669E2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8128:LOC100695529
gene id: 8128:LOC100695529
uniprot id: A0A669DAY8
uniprot id: I3J141
names: Similarity
messages: Belongs to the pellino family.

8128:LOC100695530
gene id: 8128:LOC100695530
uniprot id: I3KJ31
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

8128:snap25
gene id: 8128:snap25
uniprot id: I3IYC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

8128:LOC100691259
gene id: 8128:LOC100691259
uniprot id: I3KAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8128:egflam
gene id: 8128:egflam
uniprot id: A0A669BAG2
uniprot id: A0A669DG55
uniprot id: I3KCH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100692645
gene id: 8128:LOC100692645
uniprot id: I3JSN9
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

8128:LOC100700292
gene id: 8128:LOC100700292
uniprot id: A0A669F5Q7
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

8128:LOC100705144
gene id: 8128:LOC100705144
uniprot id: I3K057
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

8128:LOC100701180
gene id: 8128:LOC100701180
uniprot id: A0A669EJT0
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100697401
gene id: 8128:LOC100697401
uniprot id: A0A669F486
names: Similarity
messages: Belongs to the lipin family.

8128:sppl2b
gene id: 8128:sppl2b
uniprot id: A0A669CVL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

8128:cacybp
gene id: 8128:cacybp
uniprot id: I3JUC0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

8128:LOC100697055
gene id: 8128:LOC100697055
uniprot id: A0A669DC60
uniprot id: A0A669DP57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

8128:galnt9
gene id: 8128:galnt9
uniprot id: I3JYN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:txnl4b
gene id: 8128:txnl4b
uniprot id: I3J4X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

8128:phox2a
gene id: 8128:phox2a
uniprot id: A0A669EQY5
names: Subcellular Location Annotation
messages: Nucleus

8128:Mb
gene id: 8128:Mb
uniprot id: B9A9D4
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

8128:LOC100709097
gene id: 8128:LOC100709097
uniprot id: A0A669EQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8128:hps5
gene id: 8128:hps5
uniprot id: I3KES8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

8128:lrp5
gene id: 8128:lrp5
uniprot id: A0A669C726
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:gli2
gene id: 8128:gli2
uniprot id: I3J9T9
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8128:LOC100704314
gene id: 8128:LOC100704314
uniprot id: A0A669CUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8128:itih2
gene id: 8128:itih2
uniprot id: A0A669C0R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

8128:rfc1
gene id: 8128:rfc1
uniprot id: I3JR06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

8128:LOC100707972
gene id: 8128:LOC100707972
uniprot id: A0A669F794
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

8128:LOC100710713
gene id: 8128:LOC100710713
uniprot id: I3JSE6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC102076968
gene id: 8128:LOC102076968
uniprot id: A0A669CWB1
names: Similarity
messages: Belongs to the FAM83 family.

8128:LOC100694824
gene id: 8128:LOC100694824
uniprot id: I3KC66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100702341
gene id: 8128:LOC100702341
uniprot id: I3KTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:LOC100534577
gene id: 8128:LOC100534577
uniprot id: I3K5D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:tmem41a
gene id: 8128:tmem41a
uniprot id: A0A669C9M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

8128:polr3c
gene id: 8128:polr3c
uniprot id: I3JGN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

8128:crebl2
gene id: 8128:crebl2
uniprot id: I3JKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

8128:gpbp1l1
gene id: 8128:gpbp1l1
uniprot id: I3KQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

8128:LOC100704500
gene id: 8128:LOC100704500
uniprot id: I3JBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

8128:cnksr2
gene id: 8128:cnksr2
uniprot id: I3JH52
names: Similarity
messages: Belongs to the CNKSR family.

8128:gtf2a2
gene id: 8128:gtf2a2
uniprot id: A0A669D1S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

8128:gphb5
gene id: 8128:gphb5
uniprot id: I3IZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8128:cog6
gene id: 8128:cog6
uniprot id: I3JE67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

8128:tspan6
gene id: 8128:tspan6
uniprot id: I3J346
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:rpl14
gene id: 8128:rpl14
uniprot id: A0A669C805
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

8128:lrrc4
gene id: 8128:lrrc4
uniprot id: I3KYS0
names: Subcellular Location Annotation
messages: Membrane

8128:hapln4
gene id: 8128:hapln4
uniprot id: I3J2L6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100704388
gene id: 8128:LOC100704388
uniprot id: A0A669CVI7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8128:LOC100700287
gene id: 8128:LOC100700287
uniprot id: I3KNT1
names: Similarity
messages: Belongs to the heme oxygenase family.

8128:LOC100712032
gene id: 8128:LOC100712032
uniprot id: I3KQ63
uniprot id: I3KQ64
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100534455
gene id: 8128:LOC100534455
uniprot id: I3KP17
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

8128:apc2
gene id: 8128:apc2
uniprot id: A0A669B847
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

8128:fgf22
gene id: 8128:fgf22
uniprot id: I3J2B6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:dyrk2
gene id: 8128:dyrk2
uniprot id: A0A669CGW2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8128:LOC100701765
gene id: 8128:LOC100701765
uniprot id: A0A669CH53
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

8128:oplah
gene id: 8128:oplah
uniprot id: I3KAG3
names: Similarity
messages: Belongs to the oxoprolinase family.

8128:smad6
gene id: 8128:smad6
uniprot id: A0A669BL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100709221
gene id: 8128:LOC100709221
uniprot id: A0A669BC75
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

8128:LOC100705846
gene id: 8128:LOC100705846
uniprot id: A0A669C5X5
names: Similarity
messages: Belongs to the CD36 family.

8128:LOC100700332
gene id: 8128:LOC100700332
uniprot id: A0A669BMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

8128:zfyve28
gene id: 8128:zfyve28
uniprot id: I3KW64
names: Similarity
messages: Belongs to the lst-2 family.

8128:polr2m
gene id: 8128:polr2m
uniprot id: I3JEM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

8128:trmt112
gene id: 8128:trmt112
uniprot id: I3JD29
names: Similarity
messages: Belongs to the TRM112 family.

8128:LOC100691440
gene id: 8128:LOC100691440
uniprot id: I3IXY7
names: Subcellular Location Annotation
messages: Nucleus

8128:fam135b
gene id: 8128:fam135b
uniprot id: I3JL96
names: Similarity
messages: Belongs to the FAM135 family.

8128:LOC100694356
gene id: 8128:LOC100694356
uniprot id: I3K851
names: Subcellular Location Annotation
messages: Membrane

8128:aars2
gene id: 8128:aars2
uniprot id: I3JK62
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

8128:LOC100707978
gene id: 8128:LOC100707978
uniprot id: A0A669CB21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8128:esyt2
gene id: 8128:esyt2
uniprot id: I3JFA9
uniprot id: I3JFB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100702394
gene id: 8128:LOC100702394
uniprot id: I3KM97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8128:ddx24
gene id: 8128:ddx24
uniprot id: A0A669EV01
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8128:LOC100711262
gene id: 8128:LOC100711262
uniprot id: A0A669DGW1
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

8128:tma16
gene id: 8128:tma16
uniprot id: I3JUW2
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

8128:mppe1
gene id: 8128:mppe1
uniprot id: A0A669B930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

8128:ing3
gene id: 8128:ing3
uniprot id: I3JKX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8128:LOC100695336
gene id: 8128:LOC100695336
uniprot id: A0A669D9U9
uniprot id: I3J4H3
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

8128:LOC100705257
gene id: 8128:LOC100705257
uniprot id: A0A669DVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:sgk1
gene id: 8128:sgk1
uniprot id: A0A669DD16
uniprot id: I3IVD3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:sar1b
gene id: 8128:sar1b
uniprot id: A0A669DI10
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

8128:LOC100693886
gene id: 8128:LOC100693886
uniprot id: A0A669D595
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8128:LOC100702979
gene id: 8128:LOC100702979
uniprot id: I3JPL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8128:LOC100702414
gene id: 8128:LOC100702414
uniprot id: I3JTH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8128:pigx
gene id: 8128:pigx
uniprot id: I3J3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.

8128:ccdc124
gene id: 8128:ccdc124
uniprot id: I3K409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC124 family.
messages: Midbody

8128:LOC100691191
gene id: 8128:LOC100691191
uniprot id: I3J5V0
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8128:hnrnpa1
gene id: 8128:hnrnpa1
uniprot id: I3K2T0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100708767
gene id: 8128:LOC100708767
uniprot id: I3KII4
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100703480
gene id: 8128:LOC100703480
uniprot id: I3J9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8128:LOC102081358
gene id: 8128:LOC102081358
uniprot id: I3JTH4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

8128:edem1
gene id: 8128:edem1
uniprot id: A0A669EPC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8128:LOC100697444
gene id: 8128:LOC100697444
uniprot id: A0A669BHD2
names: Similarity
messages: Belongs to the JIP scaffold family.

8128:rmnd1
gene id: 8128:rmnd1
uniprot id: I3IW81
names: Similarity
messages: Belongs to the RMD1/sif2 family.

8128:mgme1
gene id: 8128:mgme1
uniprot id: I3JUQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGME1 family.
messages: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair.
messages: Mitochondrion

8128:insig1
gene id: 8128:insig1
uniprot id: I3JF34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

8128:thbs1
gene id: 8128:thbs1
uniprot id: C5HIF3
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:znf622
gene id: 8128:znf622
uniprot id: I3K3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

8128:LOC102080041
gene id: 8128:LOC102080041
uniprot id: A0A669CMC8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC102078965
gene id: 8128:LOC102078965
uniprot id: A0A669E757
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:stac
gene id: 8128:stac
uniprot id: I3J6L3
uniprot id: I3J6L4
names: Subcellular Location Annotation
messages: sarcolemma

8128:LOC100709775
gene id: 8128:LOC100709775
uniprot id: I3J7Y2
names: Subcellular Location Annotation
messages: P-body

8128:LOC100689881
gene id: 8128:LOC100689881
uniprot id: I3KF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

8128:LOC100693041
gene id: 8128:LOC100693041
uniprot id: I3JS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

8128:negr1
gene id: 8128:negr1
uniprot id: I3J398
uniprot id: I3J399
names: Subcellular Location Annotation
messages: Membrane

8128:ndufv3
gene id: 8128:ndufv3
uniprot id: A0A669E4G7
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

8128:LOC100711209
gene id: 8128:LOC100711209
uniprot id: A0A669BRW0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

8128:LOC100711410
gene id: 8128:LOC100711410
uniprot id: I3KHX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:txndc5
gene id: 8128:txndc5
uniprot id: I3KB19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8128:cntnap2
gene id: 8128:cntnap2
uniprot id: I3KAN1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

8128:LOC100695091
gene id: 8128:LOC100695091
uniprot id: I3JV83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

8128:LOC102075649
gene id: 8128:LOC102075649
uniprot id: A0A669F3R4
names: Similarity
messages: Belongs to the arrestin family.

8128:atp6v1f
gene id: 8128:atp6v1f
uniprot id: A0A669EGV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8128:LOC100702162
gene id: 8128:LOC100702162
uniprot id: I3K1G5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane

8128:arl5b
gene id: 8128:arl5b
uniprot id: A0A669DGF1
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8128:itga1
gene id: 8128:itga1
uniprot id: A0A669F7F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC102081412
gene id: 8128:LOC102081412
uniprot id: A0A669CIX5
uniprot id: A0A669DB42
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100701093
gene id: 8128:LOC100701093
uniprot id: A0A669CEZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100709798
gene id: 8128:LOC100709798
uniprot id: I3JGT0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

8128:cct3
gene id: 8128:cct3
uniprot id: I3KDS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8128:arl3
gene id: 8128:arl3
uniprot id: I3KFL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8128:LOC100694990
gene id: 8128:LOC100694990
uniprot id: A0A669EAA5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100691684
gene id: 8128:LOC100691684
uniprot id: A0A669CM24
uniprot id: I3IZ49
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8128:LOC100705941
gene id: 8128:LOC100705941
uniprot id: I3JYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100707964
gene id: 8128:LOC100707964
uniprot id: I3J3X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:LOC100689964
gene id: 8128:LOC100689964
uniprot id: A0A669C7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

8128:LOC109196823
gene id: 8128:LOC109196823
uniprot id: A0A669B0S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

8128:LOC102080433
gene id: 8128:LOC102080433
uniprot id: I3KRR8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100692530
gene id: 8128:LOC100692530
uniprot id: A0A669D773
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8128:LOC100705545
gene id: 8128:LOC100705545
uniprot id: I3IZ82
names: Similarity
messages: Belongs to the S-100 family.

8128:tbcc
gene id: 8128:tbcc
uniprot id: I3KY93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCC family.
messages: Cytoplasm
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.

8128:fam168a
gene id: 8128:fam168a
uniprot id: I3JBX2
names: Similarity
messages: Belongs to the FAM168 family.

8128:nxph2
gene id: 8128:nxph2
uniprot id: I3J9P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8128:LOC100703341
gene id: 8128:LOC100703341
uniprot id: A0A669CYE4
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8128:LOC100703788
gene id: 8128:LOC100703788
uniprot id: I3K1R3
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8128:LOC100699221
gene id: 8128:LOC100699221
uniprot id: A0A669B2E7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

8128:myh9
gene id: 8128:myh9
uniprot id: I3JMZ2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100710763
gene id: 8128:LOC100710763
uniprot id: I3JX43
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8128:LOC100690829
gene id: 8128:LOC100690829
uniprot id: I3KML9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8128:fbl
gene id: 8128:fbl
uniprot id: I3JMN4
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

8128:pik3ip1
gene id: 8128:pik3ip1
uniprot id: A0A669ENK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100711213
gene id: 8128:LOC100711213
uniprot id: I3K4L0
names: Similarity
messages: Belongs to the BicD family.

8128:LOC100712477
gene id: 8128:LOC100712477
uniprot id: I3K7K5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102083100
gene id: 8128:LOC102083100
uniprot id: A0A669CNK5
uniprot id: A0A669F6J9
names: Subcellular Location Annotation
messages: extracellular space

8128:neu3b
gene id: 8128:neu3b
uniprot id: A0A024FS75
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8128:LOC100708656
gene id: 8128:LOC100708656
uniprot id: A0A669CI72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

8128:manbal
gene id: 8128:manbal
uniprot id: A0A669E2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

8128:mre11
gene id: 8128:mre11
uniprot id: I3JFJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

8128:LOC100709027
gene id: 8128:LOC100709027
uniprot id: A0A669AXB3
names: Similarity
messages: Belongs to the TPPP family.

8128:LOC100690263
gene id: 8128:LOC100690263
uniprot id: I3KRU5
names: Function
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

8128:sostdc1
gene id: 8128:sostdc1
uniprot id: I3JHG1
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:elac1
gene id: 8128:elac1
uniprot id: I3KCY9
names: Subunit
messages: Homodimer.

8128:plppr3
gene id: 8128:plppr3
uniprot id: I3JA54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:LOC100690410
gene id: 8128:LOC100690410
uniprot id: I3JN86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

8128:LOC100697502
gene id: 8128:LOC100697502
uniprot id: I3IW57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:LOC100690266
gene id: 8128:LOC100690266
uniprot id: A0A669EQ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:capzb
gene id: 8128:capzb
uniprot id: A0A669DIZ3
uniprot id: A0A669E3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

8128:LOC100692416
gene id: 8128:LOC100692416
uniprot id: A0A669CRX2
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

8128:ints14
gene id: 8128:ints14
uniprot id: I3KE50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

8128:LOC100704914
gene id: 8128:LOC100704914
uniprot id: A0A669CSM7
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:tasp1
gene id: 8128:tasp1
uniprot id: A0A669D6G8
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8128:LOC100704692
gene id: 8128:LOC100704692
uniprot id: A0A669BMN3
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8128:LOC100697439
gene id: 8128:LOC100697439
uniprot id: I3JC29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:brca1
gene id: 8128:brca1
uniprot id: I3KHG1
names: Subcellular Location Annotation
messages: Chromosome

8128:perp
gene id: 8128:perp
uniprot id: A0A669B414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8128:LOC100710423
gene id: 8128:LOC100710423
uniprot id: A0A669EEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

8128:LOC100707994
gene id: 8128:LOC100707994
uniprot id: I3K7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8128:LOC100701380
gene id: 8128:LOC100701380
uniprot id: I3KFP0
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8128:LOC100700681
gene id: 8128:LOC100700681
uniprot id: A0A669EQF8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100696606
gene id: 8128:LOC100696606
uniprot id: I3KWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100711586
gene id: 8128:LOC100711586
uniprot id: A0A669BK16
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:eri1
gene id: 8128:eri1
uniprot id: I3KN10
names: Subcellular Location Annotation
messages: Cytoplasm

8128:lg7h11orf49
gene id: 8128:lg7h11orf49
uniprot id: A0A669E1Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: cytoskeleton

8128:LOC100691877
gene id: 8128:LOC100691877
uniprot id: I3KTA0
names: Similarity
messages: Belongs to the copine family.

8128:soat1
gene id: 8128:soat1
uniprot id: A0A669CTW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100705688
gene id: 8128:LOC100705688
uniprot id: I3K2A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8128:LOC100702686
gene id: 8128:LOC100702686
uniprot id: I3IVI0
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

8128:mlec
gene id: 8128:mlec
uniprot id: I3JZ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC109202788
gene id: 8128:LOC109202788
uniprot id: I3KXR4
names: Subunit
messages: Interacts with ATP6V0C.

8128:LOC100709904
gene id: 8128:LOC100709904
uniprot id: A0A669BGM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

8128:LOC100712102
gene id: 8128:LOC100712102
uniprot id: I3JXF1
names: Similarity
messages: Belongs to the serpin family.

8128:LOC100696753
gene id: 8128:LOC100696753
uniprot id: I3KXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100706113
gene id: 8128:LOC100706113
uniprot id: I3J6X7
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

8128:LOC100699206
gene id: 8128:LOC100699206
uniprot id: A0A669F6X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

8128:LOC100698516
gene id: 8128:LOC100698516
uniprot id: A0A669C098
uniprot id: A0A669C9Z5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8128:naa10
gene id: 8128:naa10
uniprot id: I3K1U9
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

8128:tyrp1
gene id: 8128:tyrp1
uniprot id: I3JL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8128:pgap3
gene id: 8128:pgap3
uniprot id: A0A669DPA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Membrane

8128:stk32a
gene id: 8128:stk32a
uniprot id: I3JNX4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100702173
gene id: 8128:LOC100702173
uniprot id: I3JPS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

8128:xkr6
gene id: 8128:xkr6
uniprot id: I3KDW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:LOC100705722
gene id: 8128:LOC100705722
uniprot id: A0A669C2X9
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

8128:vps26c
gene id: 8128:vps26c
uniprot id: I3KL78
names: Similarity
messages: Belongs to the VPS26 family.

8128:LOC100696772
gene id: 8128:LOC100696772
uniprot id: A0A669C4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8128:KEH09 p13
gene id: 8128:KEH09_p13
uniprot id: D2KP24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:tdrd5
gene id: 8128:tdrd5
uniprot id: I3K9I6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:smoc2
gene id: 8128:smoc2
uniprot id: I3JVI1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:tmcc3
gene id: 8128:tmcc3
uniprot id: A0A669B5Y1
uniprot id: I3KN08
names: Similarity
messages: Belongs to the TEX28 family.

8128:LOC100702382
gene id: 8128:LOC100702382
uniprot id: I3JIK0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8128:LOC100704800
gene id: 8128:LOC100704800
uniprot id: A0A669CTT9
names: Subcellular Location Annotation
messages: Membrane

8128:fev
gene id: 8128:fev
uniprot id: A0A669DFY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC100690035
gene id: 8128:LOC100690035
uniprot id: I3K1Y8
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:slc35a1
gene id: 8128:slc35a1
uniprot id: A0A669CKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:map3k10
gene id: 8128:map3k10
uniprot id: I3J711
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

8128:tacc1
gene id: 8128:tacc1
uniprot id: I3K7P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

8128:rev1
gene id: 8128:rev1
uniprot id: I3K9J6
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

8128:pex19
gene id: 8128:pex19
uniprot id: I3KDB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

8128:LOC100702614
gene id: 8128:LOC100702614
uniprot id: A0A669EMX8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100712110
gene id: 8128:LOC100712110
uniprot id: I3KZI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100695648
gene id: 8128:LOC100695648
uniprot id: A0A669EFK9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:nsg2
gene id: 8128:nsg2
uniprot id: A0A669DHQ1
names: Similarity
messages: Belongs to the NSG family.

8128:LOC100710680
gene id: 8128:LOC100710680
uniprot id: I3KII2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8128:ighmbp2
gene id: 8128:ighmbp2
uniprot id: I3KEG9
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

8128:cmpk2
gene id: 8128:cmpk2
uniprot id: I3J6W2
names: Similarity
messages: Belongs to the thymidylate kinase family.

8128:crh
gene id: 8128:crh
uniprot id: I3KX79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

8128:LOC100701444
gene id: 8128:LOC100701444
uniprot id: A0A669F687
names: Similarity
messages: Belongs to the HARBI1 family.

8128:nek3
gene id: 8128:nek3
uniprot id: A0A669CKH6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100700603
gene id: 8128:LOC100700603
uniprot id: I3KYT8
names: Subcellular Location Annotation
messages: Membrane

8128:mtfr2
gene id: 8128:mtfr2
uniprot id: I3IVH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

8128:LOC100691436
gene id: 8128:LOC100691436
uniprot id: A0A669FBD9
names: Subcellular Location Annotation
messages: Nucleus

8128:khdrbs2
gene id: 8128:khdrbs2
uniprot id: I3JTQ7
names: Similarity
messages: Belongs to the KHDRBS family.

8128:LOC100709933
gene id: 8128:LOC100709933
uniprot id: I3KJW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

8128:LOC100698415
gene id: 8128:LOC100698415
uniprot id: A0A669B2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

8128:LOC100705895
gene id: 8128:LOC100705895
uniprot id: I3JXE3
names: Similarity
messages: Belongs to the peptidase S28 family.

8128:LOC100701603
gene id: 8128:LOC100701603
uniprot id: A0A669AUZ1
uniprot id: I3JTD4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-97 and Arg-100) that bind to malonylated and succinylated substrates and define the specificity.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-99 and Arg-102) that bind to malonylated and succinylated substrates and define the specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

8128:e2f2
gene id: 8128:e2f2
uniprot id: A0A669B4F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8128:ankrd13d
gene id: 8128:ankrd13d
uniprot id: A0A669F895
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8128:grik4
gene id: 8128:grik4
uniprot id: A0A669AWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:elf2
gene id: 8128:elf2
uniprot id: I3J5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:kcnh8
gene id: 8128:kcnh8
uniprot id: A0A669DDK0
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8128:LOC100692035
gene id: 8128:LOC100692035
uniprot id: I3J5T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8128:LOC100711363
gene id: 8128:LOC100711363
uniprot id: A0A669EF85
uniprot id: I3IW54
names: Similarity
messages: Belongs to the SOGA family.

8128:LOC100701389
gene id: 8128:LOC100701389
uniprot id: A0A669DVJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:svopl
gene id: 8128:svopl
uniprot id: A0A669CBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8128:LOC100706148
gene id: 8128:LOC100706148
uniprot id: I3JQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

8128:cdc73
gene id: 8128:cdc73
uniprot id: A0A669DMW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

8128:LOC100708339
gene id: 8128:LOC100708339
uniprot id: A0A669DQX6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:wdfy2
gene id: 8128:wdfy2
uniprot id: A0A669D3P2
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8128:LOC100712311
gene id: 8128:LOC100712311
uniprot id: A0A669F304
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100689789
gene id: 8128:LOC100689789
uniprot id: I3KB86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8128:cul9
gene id: 8128:cul9
uniprot id: A0A669CRV8
uniprot id: I3JJB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

8128:LOC100710636
gene id: 8128:LOC100710636
uniprot id: I3J898
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:pfdn4
gene id: 8128:pfdn4
uniprot id: I3KIB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

8128:mark2
gene id: 8128:mark2
uniprot id: I3K7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

8128:sphkap
gene id: 8128:sphkap
uniprot id: A0A669DA42
names: Similarity
messages: Belongs to the AKAP110 family.

8128:LOC100691083
gene id: 8128:LOC100691083
uniprot id: A0A669EFA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

8128:tspan33
gene id: 8128:tspan33
uniprot id: A0A669C430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:rprd1a
gene id: 8128:rprd1a
uniprot id: I3J270
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

8128:timm21
gene id: 8128:timm21
uniprot id: I3KA90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

8128:LOC106096464
gene id: 8128:LOC106096464
uniprot id: A0A669BYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:map3k21
gene id: 8128:map3k21
uniprot id: I3IWQ9
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

8128:adprhl2
gene id: 8128:adprhl2
uniprot id: A0A669D9W7
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

8128:LOC100705111
gene id: 8128:LOC100705111
uniprot id: I3J3A4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100705715
gene id: 8128:LOC100705715
uniprot id: I3KEC4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100694302
gene id: 8128:LOC100694302
uniprot id: A0A669DF56
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:fam171a1
gene id: 8128:fam171a1
uniprot id: A0A669DAL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8128:traf3
gene id: 8128:traf3
uniprot id: I3K142
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8128:LOC100708007
gene id: 8128:LOC100708007
uniprot id: I3JAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8128:LOC106096996
gene id: 8128:LOC106096996
uniprot id: A0A669B869
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8128:adam22
gene id: 8128:adam22
uniprot id: A0A669BYW4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100694299
gene id: 8128:LOC100694299
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:itfg1
gene id: 8128:itfg1
uniprot id: I3J501
names: Similarity
messages: Belongs to the TIP family.

8128:LOC100707762
gene id: 8128:LOC100707762
uniprot id: A0A669DYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

8128:cenpm
gene id: 8128:cenpm
uniprot id: I3KNL5
names: Subcellular Location Annotation
messages: Nucleus

8128:psma5
gene id: 8128:psma5
uniprot id: I3KT68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8128:LOC100708036
gene id: 8128:LOC100708036
uniprot id: A0A669BK54
uniprot id: I3JTM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:LOC100695500
gene id: 8128:LOC100695500
uniprot id: A0A669BNU0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8128:adamts1
gene id: 8128:adamts1
uniprot id: I3K2F8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:spr
gene id: 8128:spr
uniprot id: I3K460
names: Similarity
messages: Belongs to the sepiapterin reductase family.

8128:armc9
gene id: 8128:armc9
uniprot id: A0A669B6I8
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cilium basal body

8128:LOC100703799
gene id: 8128:LOC100703799
uniprot id: A0A669EST5
names: Similarity
messages: Belongs to the taxilin family.

8128:gng7
gene id: 8128:gng7
uniprot id: I3KSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:polr3h
gene id: 8128:polr3h
uniprot id: I3JP22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

8128:naaladl1
gene id: 8128:naaladl1
uniprot id: I3KJV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

8128:dazap2
gene id: 8128:dazap2
uniprot id: A0A669CTR8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: nuclear body

8128:LOC100704480
gene id: 8128:LOC100704480
uniprot id: I3JV72
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102081481
gene id: 8128:LOC102081481
uniprot id: I3J7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

8128:patl2
gene id: 8128:patl2
uniprot id: I3K055
names: Similarity
messages: Belongs to the PAT1 family.

8128:LOC100694688
gene id: 8128:LOC100694688
uniprot id: A0A669BM04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100534462
gene id: 8128:LOC100534462
uniprot id: I3JA95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:LOC100709969
gene id: 8128:LOC100709969
uniprot id: I3JUD3
names: Subcellular Location Annotation
messages: cytoskeleton

8128:LOC100695412
gene id: 8128:LOC100695412
uniprot id: A0A669DJN2
uniprot id: A0A669E1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nectin family.
messages: Membrane

8128:paxbp1
gene id: 8128:paxbp1
uniprot id: I3JAY6
names: Similarity
messages: Belongs to the GCF family.

8128:LOC100696824
gene id: 8128:LOC100696824
uniprot id: A0A669CR11
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100695394
gene id: 8128:LOC100695394
uniprot id: I3KMW0
uniprot id: I3KMW3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8128:inppl1
gene id: 8128:inppl1
uniprot id: I3KIZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium

8128:coq2
gene id: 8128:coq2
uniprot id: A0A669B4G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

8128:LOC100708325
gene id: 8128:LOC100708325
uniprot id: I3KB72
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

8128:hdac9
gene id: 8128:hdac9
uniprot id: I3J443
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus

8128:LOC100704239
gene id: 8128:LOC100704239
uniprot id: I3IVV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8128:LOC100707255
gene id: 8128:LOC100707255
uniprot id: I3K432
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8128:LOC100702704
gene id: 8128:LOC100702704
uniprot id: A0A669D3Y8
names: Similarity
messages: Belongs to the globin family.

8128:otp
gene id: 8128:otp
uniprot id: I3KEB3
names: Subcellular Location Annotation
messages: Nucleus

8128:ndufb9
gene id: 8128:ndufb9
uniprot id: I3JJS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8128:LOC100707713
gene id: 8128:LOC100707713
uniprot id: I3K879
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

8128:LOC100691806
gene id: 8128:LOC100691806
uniprot id: A0A669DJX6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

8128:slc35f2
gene id: 8128:slc35f2
uniprot id: I3JSZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

8128:LOC100697380
gene id: 8128:LOC100697380
uniprot id: A0A669DA33
uniprot id: I3J6C0
names: Similarity
messages: Belongs to the BtpA family.

8128:LOC100689713
gene id: 8128:LOC100689713
uniprot id: A0A669BMW1
uniprot id: I3KKP2
names: Subcellular Location Annotation
messages: cytoskeleton

8128:uba2
gene id: 8128:uba2
uniprot id: A0A669F2G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

8128:LOC100702148
gene id: 8128:LOC100702148
uniprot id: I3JTE8
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:mrpl4
gene id: 8128:mrpl4
uniprot id: A0A669B5X1
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

8128:LOC100696095
gene id: 8128:LOC100696095
uniprot id: A0A669BEN7
names: Similarity
messages: Belongs to the FRAS1 family.

8128:LOC100695763
gene id: 8128:LOC100695763
uniprot id: I3JAI4
names: Subcellular Location Annotation
messages: extracellular space

8128:nol11
gene id: 8128:nol11
uniprot id: I3JH07
names: Subcellular Location Annotation
messages: nucleolus

8128:LOC100693402
gene id: 8128:LOC100693402
uniprot id: A0A669B612
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8128:LOC100698871
gene id: 8128:LOC100698871
uniprot id: I3KHK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8128:chaf1b
gene id: 8128:chaf1b
uniprot id: I3KG81
names: Subcellular Location Annotation
messages: Nucleus

8128:usp48
gene id: 8128:usp48
uniprot id: I3JQ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

8128:LOC100690681
gene id: 8128:LOC100690681
uniprot id: A0A669C900
uniprot id: A0A669D450
names: Similarity
messages: Belongs to the FAM83 family.

8128:zdhhc6
gene id: 8128:zdhhc6
uniprot id: I3KH45
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100703704
gene id: 8128:LOC100703704
uniprot id: A0A669CBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

8128:LOC100696070
gene id: 8128:LOC100696070
uniprot id: I3KS63
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:gchfr
gene id: 8128:gchfr
uniprot id: A0A669AZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

8128:LOC100696983
gene id: 8128:LOC100696983
uniprot id: A0A669C2Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8128:pltp
gene id: 8128:pltp
uniprot id: A0A669DK25
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

8128:clptm1
gene id: 8128:clptm1
uniprot id: A0A669DKX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

8128:LOC100699860
gene id: 8128:LOC100699860
uniprot id: I3K968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

8128:eif4h
gene id: 8128:eif4h
uniprot id: A0A669B3J1
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

8128:sec24d
gene id: 8128:sec24d
uniprot id: I3JL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8128:bmp3
gene id: 8128:bmp3
uniprot id: I3K955
names: Similarity
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.

8128:LOC100700288
gene id: 8128:LOC100700288
uniprot id: I3J6B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:etv6
gene id: 8128:etv6
uniprot id: A0A669BTE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC100707455
gene id: 8128:LOC100707455
uniprot id: I3KD76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8128:dpy19l4
gene id: 8128:dpy19l4
uniprot id: I3K8G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

8128:ctsz
gene id: 8128:ctsz
uniprot id: A0A669DE61
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:ccnk
gene id: 8128:ccnk
uniprot id: A0A669DLA0
names: Similarity
names: Subunit
messages: Belongs to the cyclin family.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8128:cpsf4
gene id: 8128:cpsf4
uniprot id: A0A669BZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

8128:rfc2
gene id: 8128:rfc2
uniprot id: A0A669AWQ2
names: Similarity
messages: Belongs to the activator 1 small subunits family.

8128:LOC100711814
gene id: 8128:LOC100711814
uniprot id: I3KYN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

8128:gtdc1
gene id: 8128:gtdc1
uniprot id: I3JEM3
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

8128:hsd11b2
gene id: 8128:hsd11b2
uniprot id: Q7ZZV0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100700722
gene id: 8128:LOC100700722
uniprot id: A0A669BV10
uniprot id: A0A669EY87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100706733
gene id: 8128:LOC100706733
uniprot id: A0A669BL75
names: Subcellular Location Annotation
messages: Membrane

8128:cast
gene id: 8128:cast
uniprot id: A0A669BSY3
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I27 (calpastatin) family.
messages: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.

8128:LOC100703974
gene id: 8128:LOC100703974
uniprot id: A0A2Z2H0W6
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:bet1
gene id: 8128:bet1
uniprot id: A0A669C7X1
names: Subcellular Location Annotation
messages: Membrane

8128:fam76b
gene id: 8128:fam76b
uniprot id: I3J9A6
names: Similarity
messages: Belongs to the FAM76 family.

8128:gstcd
gene id: 8128:gstcd
uniprot id: I3KLV6
names: Similarity
messages: Belongs to the GSTCD family.

8128:npr1
gene id: 8128:npr1
uniprot id: A0A669ETA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8128:LOC100702922
gene id: 8128:LOC100702922
uniprot id: I3KW26
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8128:htt
gene id: 8128:htt
uniprot id: A0A669C4G5
uniprot id: A0A669EYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

8128:etv4
gene id: 8128:etv4
uniprot id: I3KPD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC109198966
gene id: 8128:LOC109198966
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:gpn2
gene id: 8128:gpn2
uniprot id: A0A669CID4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

8128:hadhb
gene id: 8128:hadhb
uniprot id: I3JDU8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8128:esf1
gene id: 8128:esf1
uniprot id: I3JI94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

8128:LOC100710555
gene id: 8128:LOC100710555
uniprot id: A0A669ELG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100705426
gene id: 8128:LOC100705426
uniprot id: A0A669CQP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100699599
gene id: 8128:LOC100699599
uniprot id: A0A669CR21
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

8128:taf1b
gene id: 8128:taf1b
uniprot id: I3KRD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

8128:serpini1
gene id: 8128:serpini1
uniprot id: A0A669EZW1
names: Similarity
messages: Belongs to the serpin family.

8128:pdhb
gene id: 8128:pdhb
uniprot id: I3IV89
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

8128:rft1
gene id: 8128:rft1
uniprot id: I3KS75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

8128:LOC100702473
gene id: 8128:LOC100702473
uniprot id: I3K6P1
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC100691479
gene id: 8128:LOC100691479
uniprot id: A0A669EFP0
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100695628
gene id: 8128:LOC100695628
uniprot id: A0A669D3F2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100698804
gene id: 8128:LOC100698804
uniprot id: I3KMP7
names: Subcellular Location Annotation
messages: Membrane

8128:tmem9b
gene id: 8128:tmem9b
uniprot id: A0A669CEZ7
names: Similarity
messages: Belongs to the TMEM9 family.

8128:LOC100705620
gene id: 8128:LOC100705620
uniprot id: I3JX58
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:vps37b
gene id: 8128:vps37b
uniprot id: I3KGG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8128:myo16
gene id: 8128:myo16
uniprot id: A0A669AW69
uniprot id: A0A669EBU8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100691799
gene id: 8128:LOC100691799
uniprot id: I3JLI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins.
messages: Nucleus

8128:cutc
gene id: 8128:cutc
uniprot id: I3JST0
names: Similarity
messages: Belongs to the CutC family.

8128:fscn1
gene id: 8128:fscn1
uniprot id: A0A669EKR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8128:abcg4
gene id: 8128:abcg4
uniprot id: D0Q1I2
uniprot id: I3JD06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8128:mcm4
gene id: 8128:mcm4
uniprot id: I3JSZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

8128:LOC100711745
gene id: 8128:LOC100711745
uniprot id: A0A669B8C8
uniprot id: A0A669F1B0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

8128:LOC100698922
gene id: 8128:LOC100698922
uniprot id: I3J201
names: Subcellular Location Annotation
messages: Membrane

8128:ebp
gene id: 8128:ebp
uniprot id: I3K2X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:nmd3
gene id: 8128:nmd3
uniprot id: I3J6U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100707106
gene id: 8128:LOC100707106
uniprot id: I3JD04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

8128:LOC100701639
gene id: 8128:LOC100701639
uniprot id: A0A669C787
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100698985
gene id: 8128:LOC100698985
uniprot id: A0A669AWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:cdh15
gene id: 8128:cdh15
uniprot id: I3J4K2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8128:ndufab1
gene id: 8128:ndufab1
uniprot id: I3KF61
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

8128:dus3l
gene id: 8128:dus3l
uniprot id: I3KUX3
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

8128:LOC102082324
gene id: 8128:LOC102082324
uniprot id: A0A669DR32
uniprot id: A0A669E8N4
uniprot id: I3K3T0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100703931
gene id: 8128:LOC100703931
uniprot id: A0A669EZQ7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:snf8
gene id: 8128:snf8
uniprot id: I3KP81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

8128:cmtm8
gene id: 8128:cmtm8
uniprot id: A0A669C6I9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707615
gene id: 8128:LOC100707615
uniprot id: I3J3S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC109195088
gene id: 8128:LOC109195088
uniprot id: A0A669AWN4
names: Similarity
messages: Belongs to the cornifelin family.

8128:LOC100705841
gene id: 8128:LOC100705841
uniprot id: I3IW16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

8128:LOC100707142
gene id: 8128:LOC100707142
uniprot id: I3J4B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

8128:mtfmt
gene id: 8128:mtfmt
uniprot id: I3KBC2
names: Similarity
messages: Belongs to the Fmt family.

8128:LOC100702544
gene id: 8128:LOC100702544
uniprot id: I3IW66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

8128:galnt16
gene id: 8128:galnt16
uniprot id: I3IV52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100712401
gene id: 8128:LOC100712401
uniprot id: A0A669BTW8
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8128:LOC100704125
gene id: 8128:LOC100704125
uniprot id: I3KUU9
names: Similarity
messages: Belongs to the globin family.

8128:LOC100711978
gene id: 8128:LOC100711978
uniprot id: A0A669C3Z2
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

8128:LOC100698829
gene id: 8128:LOC100698829
uniprot id: I3KS86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100700925
gene id: 8128:LOC100700925
uniprot id: A0A669CJS8
uniprot id: A0A669F1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:snrpd2
gene id: 8128:snrpd2
uniprot id: A0A669D448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

8128:LOC100534558
gene id: 8128:LOC100534558
uniprot id: Q1KL30
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8128:LOC100707667
gene id: 8128:LOC100707667
uniprot id: A0A669E258
names: Subcellular Location Annotation
messages: Membrane

8128:dhodh
gene id: 8128:dhodh
uniprot id: A0A669BQU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

8128:LOC100690458
gene id: 8128:LOC100690458
uniprot id: I3JD32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

8128:LOC100692331
gene id: 8128:LOC100692331
uniprot id: A0A669C6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8128:clrn2
gene id: 8128:clrn2
uniprot id: A0A669B5Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

8128:LOC100700725
gene id: 8128:LOC100700725
uniprot id: A0A669ERC6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:foxn2
gene id: 8128:foxn2
uniprot id: I3JU38
names: Subcellular Location Annotation
messages: Nucleus

8128:sf3a2
gene id: 8128:sf3a2
uniprot id: A0A669BZK8
names: Similarity
messages: Belongs to the SF3A2 family.

8128:slco2b1
gene id: 8128:slco2b1
uniprot id: I3J8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8128:LOC100705048
gene id: 8128:LOC100705048
uniprot id: A0A669CBE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:cth
gene id: 8128:cth
uniprot id: A0A669EUB1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

8128:LOC100700542
gene id: 8128:LOC100700542
uniprot id: A0A669DFC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:nkx6-1
gene id: 8128:nkx6-1
uniprot id: A0A669B100
names: Subcellular Location Annotation
messages: Nucleus

8128:rbm46
gene id: 8128:rbm46
uniprot id: A0A669BLE6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:neurod2
gene id: 8128:neurod2
uniprot id: I3KYN7
names: Subcellular Location Annotation
messages: Nucleus

8128:nup50
gene id: 8128:nup50
uniprot id: I3JKQ1
names: Subcellular Location Annotation
messages: nuclear pore complex

8128:gpr83
gene id: 8128:gpr83
uniprot id: A0A669C666
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:tmem30a
gene id: 8128:tmem30a
uniprot id: I3KR50
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8128:wdr83os
gene id: 8128:wdr83os
uniprot id: A0A669B3K4
names: Similarity
messages: Belongs to the Asterix family.

8128:cav2
gene id: 8128:cav2
uniprot id: A0A669BX71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8128:LOC100702599
gene id: 8128:LOC100702599
uniprot id: I3JXL4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100690943
gene id: 8128:LOC100690943
uniprot id: I3KW20
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC109198419
gene id: 8128:LOC109198419
uniprot id: A0A669D1D9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709465
gene id: 8128:LOC100709465
uniprot id: I3J6P6
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8128:arv1
gene id: 8128:arv1
uniprot id: I3KPL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

8128:gpr156
gene id: 8128:gpr156
uniprot id: A0A669E417
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100692885
gene id: 8128:LOC100692885
uniprot id: I3K8T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100696615
gene id: 8128:LOC100696615
uniprot id: I3JCA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100691566
gene id: 8128:LOC100691566
uniprot id: A0A669BY85
uniprot id: A0A669DQ65
names: Similarity
messages: Belongs to the CCDC149 family.

8128:LOC100690053
gene id: 8128:LOC100690053
uniprot id: I3KIN3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102080408
gene id: 8128:LOC102080408
uniprot id: A0A669DB11
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:ube2b
gene id: 8128:ube2b
uniprot id: A0A669CEE7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:LOC100710359
gene id: 8128:LOC100710359
uniprot id: I3KGL2
names: Similarity
messages: Belongs to the ARS2 family.

8128:LOC100701682
gene id: 8128:LOC100701682
uniprot id: I3JLB8
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

8128:adam10
gene id: 8128:adam10
uniprot id: A0A669EAS2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:gsx1
gene id: 8128:gsx1
uniprot id: I3JC99
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC106098416
gene id: 8128:LOC106098416
uniprot id: A0A669E908
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

8128:serpinf1
gene id: 8128:serpinf1
uniprot id: A0A669B2H8
names: Similarity
messages: Belongs to the serpin family.

8128:myod1
gene id: 8128:myod1
uniprot id: D2XRC0
uniprot id: I3JXI0
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8128:LOC100701059
gene id: 8128:LOC100701059
uniprot id: I3L037
names: Subcellular Location Annotation
messages: Nucleus

8128:ccdc172
gene id: 8128:ccdc172
uniprot id: I3IZB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC172 family.
messages: Cytoplasm

8128:rxfp1
gene id: 8128:rxfp1
uniprot id: A0A669DZI6
uniprot id: I3IY71
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:sema4g
gene id: 8128:sema4g
uniprot id: A0A669EIA3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100698898
gene id: 8128:LOC100698898
uniprot id: I3KEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8128:LOC100693776
gene id: 8128:LOC100693776
uniprot id: I3IZG0
names: Similarity
messages: Belongs to the NipSnap family.

8128:LOC100708044
gene id: 8128:LOC100708044
uniprot id: I3KF83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:LOC102079871
gene id: 8128:LOC102079871
uniprot id: I3JKI1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100700693
gene id: 8128:LOC100700693
uniprot id: A0A669C3T9
uniprot id: I3J4Q8
names: Subcellular Location Annotation
messages: Membrane

8128:timp2
gene id: 8128:timp2
uniprot id: A0A669B1D1
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8128:LOC102083013
gene id: 8128:LOC102083013
uniprot id: A0A669C0I3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100711902
gene id: 8128:LOC100711902
uniprot id: A0A669DZM9
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100692133
gene id: 8128:LOC100692133
uniprot id: I3KJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

8128:mtfp1
gene id: 8128:mtfp1
uniprot id: A0A669EW46
names: Similarity
messages: Belongs to the MTFP1 family.

8128:LOC100697082
gene id: 8128:LOC100697082
uniprot id: I3JET7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:mapk4
gene id: 8128:mapk4
uniprot id: I3KCX4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

8128:LOC100696971
gene id: 8128:LOC100696971
uniprot id: A0A669DU61
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:rpl3l
gene id: 8128:rpl3l
uniprot id: A0A669BL80
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

8128:csk
gene id: 8128:csk
uniprot id: A0A669BCE7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:LOC109204958
gene id: 8128:LOC109204958
uniprot id: A0A669CW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:ppt1
gene id: 8128:ppt1
uniprot id: I3K7T1
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

8128:mterf3
gene id: 8128:mterf3
uniprot id: I3J2V2
names: Similarity
messages: Belongs to the mTERF family.

8128:thada
gene id: 8128:thada
uniprot id: A0A669F536
names: Function
names: Similarity
messages: Belongs to the THADA family.
messages: Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.

8128:spg7
gene id: 8128:spg7
uniprot id: A0A669D9A6
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8128:LOC100696750
gene id: 8128:LOC100696750
uniprot id: A0A669EE94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8128:LOC102082214
gene id: 8128:LOC102082214
uniprot id: A0A669EDA1
names: Similarity
messages: Belongs to the IUNH family.

8128:mocs2
gene id: 8128:mocs2
uniprot id: I3K3S6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).
messages: cytosol

8128:LOC109201539
gene id: 8128:LOC109201539
uniprot id: A0A669EGA0
names: Subcellular Location Annotation
messages: extracellular space

8128:psma3
gene id: 8128:psma3
uniprot id: A0A669C590
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8128:gipc1
gene id: 8128:gipc1
uniprot id: I3J0R3
names: Similarity
messages: Belongs to the GIPC family.

8128:LOC100697255
gene id: 8128:LOC100697255
uniprot id: I3JVL5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

8128:LOC100703479
gene id: 8128:LOC100703479
uniprot id: I3KFF4
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:krtcap2
gene id: 8128:krtcap2
uniprot id: A0A669DNT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

8128:LOC100701210
gene id: 8128:LOC100701210
uniprot id: A0A669BJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

8128:LOC100692041
gene id: 8128:LOC100692041
uniprot id: A0A669EHE8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8128:rbpms2
gene id: 8128:rbpms2
uniprot id: A0A669EYP6
uniprot id: I3JEH9
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC102082411
gene id: 8128:LOC102082411
uniprot id: I3JNS2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:rsad2
gene id: 8128:rsad2
uniprot id: I3J6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RSAD2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100691762
gene id: 8128:LOC100691762
uniprot id: I3K0F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: Secreted

8128:LOC100710697
gene id: 8128:LOC100710697
uniprot id: I3J3S7
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

8128:LOC100705593
gene id: 8128:LOC100705593
uniprot id: A0A669D0N2
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8128:LOC109204647
gene id: 8128:LOC109204647
uniprot id: A0A669F9Q9
names: Subcellular Location Annotation
messages: extracellular space

8128:ermp1
gene id: 8128:ermp1
uniprot id: A0A669AXW6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710958
gene id: 8128:LOC100710958
uniprot id: I3KXG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC102077314
gene id: 8128:LOC102077314
uniprot id: I3KKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:wnk4
gene id: 8128:wnk4
uniprot id: I3JM89
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8128:LOC100705502
gene id: 8128:LOC100705502
uniprot id: I3J655
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:mrpl47
gene id: 8128:mrpl47
uniprot id: A0A669EPL0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

8128:gjd4
gene id: 8128:gjd4
uniprot id: A0A669BHL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:inpp5d
gene id: 8128:inpp5d
uniprot id: I3KT73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

8128:tecr
gene id: 8128:tecr
uniprot id: A0A669EPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100709553
gene id: 8128:LOC100709553
uniprot id: A0A669C1H6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100696204
gene id: 8128:LOC100696204
uniprot id: A0A669DG99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8128:LOC100693638
gene id: 8128:LOC100693638
uniprot id: I3KW38
names: Similarity
messages: Belongs to the peptidase S1C family.

8128:LOC100702768
gene id: 8128:LOC100702768
uniprot id: I3JZX5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100705962
gene id: 8128:LOC100705962
uniprot id: I3JIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8128:LOC100691827
gene id: 8128:LOC100691827
uniprot id: A0A669CTS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

8128:LOC100712479
gene id: 8128:LOC100712479
uniprot id: A0A669C707
names: Similarity
messages: Belongs to the serpin family.

8128:fam120b
gene id: 8128:fam120b
uniprot id: A0A669EUK9
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

8128:LOC100703495
gene id: 8128:LOC100703495
uniprot id: I3IVI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100706121
gene id: 8128:LOC100706121
uniprot id: I3JH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8128:LOC100704302
gene id: 8128:LOC100704302
uniprot id: I3JKB3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8128:tsta3
gene id: 8128:tsta3
uniprot id: I3JYA0
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

8128:tada1
gene id: 8128:tada1
uniprot id: I3KQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

8128:mrpl12
gene id: 8128:mrpl12
uniprot id: A0A669DVD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

8128:LOC100709152
gene id: 8128:LOC100709152
uniprot id: A0A669BHI3
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

8128:LOC100707234
gene id: 8128:LOC100707234
uniprot id: I3JBU3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100703810
gene id: 8128:LOC100703810
uniprot id: A0A669FBE5
uniprot id: I3JQP9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

8128:LOC100690818
gene id: 8128:LOC100690818
uniprot id: A0A669DSK4
names: Similarity
messages: Belongs to the cystatin family.

8128:snapc3
gene id: 8128:snapc3
uniprot id: I3KLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

8128:psmd9
gene id: 8128:psmd9
uniprot id: I3K6A9
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

8128:LOC100708468
gene id: 8128:LOC100708468
uniprot id: I3JBM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC100695514
gene id: 8128:LOC100695514
uniprot id: I3K839
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:prc1
gene id: 8128:prc1
uniprot id: A0A669DLD5
names: Similarity
messages: Belongs to the MAP65/ASE1 family.

8128:LOC100697685
gene id: 8128:LOC100697685
uniprot id: I3JY25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8128:steap4
gene id: 8128:steap4
uniprot id: I3JF62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8128:ttyh3
gene id: 8128:ttyh3
uniprot id: I3IYG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8128:LOC100702885
gene id: 8128:LOC100702885
uniprot id: I3JE12
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8128:LOC100692123
gene id: 8128:LOC100692123
uniprot id: I3JU84
names: Similarity
messages: Belongs to the angiomotin family.

8128:fam192a
gene id: 8128:fam192a
uniprot id: I3JYX9
names: Subcellular Location Annotation
messages: Nucleus

8128:pcnp
gene id: 8128:pcnp
uniprot id: A0A669EK94
uniprot id: I3J5V2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

8128:lg5h6orf89
gene id: 8128:lg5h6orf89
uniprot id: I3IVM6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8128:fbln1
gene id: 8128:fbln1
uniprot id: A0A669DRT4
uniprot id: A0A669EUS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:kctd10
gene id: 8128:kctd10
uniprot id: A0A669DCS9
names: Similarity
messages: Belongs to the BACURD family.

8128:LOC100697197
gene id: 8128:LOC100697197
uniprot id: A0A669CJA2
uniprot id: A0A669CVG4
uniprot id: A0A669D709
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100534398
gene id: 8128:LOC100534398
uniprot id: A0A669B0L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

8128:LOC100695535
gene id: 8128:LOC100695535
uniprot id: A0A669F7H6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

8128:LOC100711913
gene id: 8128:LOC100711913
uniprot id: I3IY69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8128:syk
gene id: 8128:syk
uniprot id: I3JZ29
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

8128:cacnb1
gene id: 8128:cacnb1
uniprot id: A0A669E1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

8128:LOC100700366
gene id: 8128:LOC100700366
uniprot id: A0A669DY20
uniprot id: A0A669F8J1
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

8128:usp3
gene id: 8128:usp3
uniprot id: I3KDW9
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:fam32a
gene id: 8128:fam32a
uniprot id: I3J1Z8
names: Similarity
messages: Belongs to the FAM32 family.

8128:pigf
gene id: 8128:pigf
uniprot id: I3KFY6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:rnf20
gene id: 8128:rnf20
uniprot id: I3JB88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

8128:jmjd1c
gene id: 8128:jmjd1c
uniprot id: A0A669E5C4
uniprot id: I3JJS9
names: Subcellular Location Annotation
messages: Nucleus

8128:dusp12
gene id: 8128:dusp12
uniprot id: I3KID5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8128:LOC100696915
gene id: 8128:LOC100696915
uniprot id: A0A669EPY1
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

8128:LOC100708540
gene id: 8128:LOC100708540
uniprot id: A0A669DFP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8128:mon1a
gene id: 8128:mon1a
uniprot id: I3KWR2
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

8128:LOC100704234
gene id: 8128:LOC100704234
uniprot id: A0A669CW96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8128:nat16
gene id: 8128:nat16
uniprot id: I3J7Q8
names: Function
names: Miscellaneous
names: Tissue Specificity
messages: Enzyme responsible for the N-acetyl-histidine (NAH) synthesis, which is a major constituent of brain and lens of ectothermic vertebrates.
messages: Expressed exclusively in the brain and lens.
messages: Strong histidine N-acetyltransferase activity has been detected in ectothermic vertebrates and not in endothermic birds and mammals.

8128:acss2
gene id: 8128:acss2
uniprot id: A0A669EMV0
uniprot id: I3KC26
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8128:tent5b
gene id: 8128:tent5b
uniprot id: A0A669FAB6
names: Similarity
messages: Belongs to the TENT family.

8128:LOC100707650
gene id: 8128:LOC100707650
uniprot id: I3KQL3
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

8128:nrg4
gene id: 8128:nrg4
uniprot id: I3KDM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100693654
gene id: 8128:LOC100693654
uniprot id: A0A669C2T2
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

8128:LOC100707806
gene id: 8128:LOC100707806
uniprot id: I3K0B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:cct8
gene id: 8128:cct8
uniprot id: I3JB44
uniprot id: I3JB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

8128:rab9a
gene id: 8128:rab9a
uniprot id: I3KXY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

8128:LOC100695575
gene id: 8128:LOC100695575
uniprot id: A0A669EZ10
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100708383
gene id: 8128:LOC100708383
uniprot id: A0A669B670
names: Similarity
messages: Belongs to the FXYD family.

8128:LOC100709395
gene id: 8128:LOC100709395
uniprot id: A0A669DSB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

8128:pnmt
gene id: 8128:pnmt
uniprot id: I3KH70
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

8128:LOC102081637
gene id: 8128:LOC102081637
uniprot id: A0A669BDC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100690223
gene id: 8128:LOC100690223
uniprot id: A0A669BU78
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:nxn
gene id: 8128:nxn
uniprot id: I3K5Z6
names: Similarity
messages: Belongs to the nucleoredoxin family.

8128:cops5
gene id: 8128:cops5
uniprot id: I3K9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

8128:LOC100695135
gene id: 8128:LOC100695135
uniprot id: I3JPI1
names: Similarity
messages: Belongs to the arrestin family.

8128:LOC100698984
gene id: 8128:LOC100698984
uniprot id: A0A669B105
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:tcea1
gene id: 8128:tcea1
uniprot id: A0A669B444
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

8128:gnl2
gene id: 8128:gnl2
uniprot id: I3KHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

8128:LOC100702297
gene id: 8128:LOC100702297
uniprot id: A0A669EJQ7
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

8128:fan1
gene id: 8128:fan1
uniprot id: I3JNQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

8128:neu4
gene id: 8128:neu4
uniprot id: A0A0F7RPT3
uniprot id: I3J7B7
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8128:LOC109203870
gene id: 8128:LOC109203870
uniprot id: A0A669DE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:LOC100696589
gene id: 8128:LOC100696589
uniprot id: I3JGL5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8128:maml1
gene id: 8128:maml1
uniprot id: I3J9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

8128:LOC102076799
gene id: 8128:LOC102076799
uniprot id: A0A669C8S4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100712451
gene id: 8128:LOC100712451
uniprot id: I3IYA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

8128:LOC100689790
gene id: 8128:LOC100689790
uniprot id: I3K0B4
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8128:abracl
gene id: 8128:abracl
uniprot id: I3JE33
names: Similarity
messages: Belongs to the costars family.

8128:LOC100703519
gene id: 8128:LOC100703519
uniprot id: A0A669EJX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8128:LOC100704008
gene id: 8128:LOC100704008
uniprot id: A0A669F7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

8128:LOC109194850
gene id: 8128:LOC109194850
uniprot id: I3KTE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

8128:rnasek
gene id: 8128:rnasek
uniprot id: A0A669BVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

8128:LOC100694258
gene id: 8128:LOC100694258
uniprot id: I3ITR4
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

8128:kcnk6
gene id: 8128:kcnk6
uniprot id: I3JLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:LOC102081897
gene id: 8128:LOC102081897
uniprot id: A0A669ELM0
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8128:dusp7
gene id: 8128:dusp7
uniprot id: A0A669DBC5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8128:cyp11b
gene id: 8128:cyp11b
uniprot id: A0A669D5X1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100705071
gene id: 8128:LOC100705071
uniprot id: I3KQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

8128:hoxb1
gene id: 8128:hoxb1
uniprot id: I3KP89
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100706106
gene id: 8128:LOC100706106
uniprot id: I3KWZ1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8128:atm
gene id: 8128:atm
uniprot id: I3JDG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus

8128:LOC100703058
gene id: 8128:LOC100703058
uniprot id: A0A669BH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100697903
gene id: 8128:LOC100697903
uniprot id: I3KER0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:eif4a3
gene id: 8128:eif4a3
uniprot id: A0A669BXT2
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:LOC100709641
gene id: 8128:LOC100709641
uniprot id: I3K4X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100700280
gene id: 8128:LOC100700280
uniprot id: I3KCS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8128:ruvbl1
gene id: 8128:ruvbl1
uniprot id: I3KS74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

8128:LOC100707015
gene id: 8128:LOC100707015
uniprot id: A0A669EG10
uniprot id: I3KMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

8128:LOC100710376
gene id: 8128:LOC100710376
uniprot id: A0A669BJC7
uniprot id: I3KIM0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:man2c1
gene id: 8128:man2c1
uniprot id: I3KDZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

8128:ctnnb1
gene id: 8128:ctnnb1
uniprot id: I3JJR7
names: Similarity
messages: Belongs to the beta-catenin family.

8128:LOC100698852
gene id: 8128:LOC100698852
uniprot id: I3KCZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

8128:LOC100692379
gene id: 8128:LOC100692379
uniprot id: A0A669EJV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8128:LOC102083181
gene id: 8128:LOC102083181
uniprot id: A0A669BL65
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8128:hars
gene id: 8128:hars
uniprot id: A0A669C0W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

8128:LOC100702698
gene id: 8128:LOC100702698
uniprot id: I3K3W9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100710726
gene id: 8128:LOC100710726
uniprot id: I3KKK3
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8128:mtmr11
gene id: 8128:mtmr11
uniprot id: I3JPM1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8128:rpl37
gene id: 8128:rpl37
uniprot id: I3JKS5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

8128:slc19a2
gene id: 8128:slc19a2
uniprot id: I3J738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

8128:six2
gene id: 8128:six2
uniprot id: I3IX50
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100700835
gene id: 8128:LOC100700835
uniprot id: A0A669EG14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:tcf7l2
gene id: 8128:tcf7l2
uniprot id: A0A669CW51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8128:LOC100703503
gene id: 8128:LOC100703503
uniprot id: A0A669BA88
uniprot id: A0A669EFD7
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8128:LOC100697358
gene id: 8128:LOC100697358
uniprot id: I3JHY8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

8128:smg6
gene id: 8128:smg6
uniprot id: I3JDU9
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini.
messages: Plays a role in nonsense-mediated mRNA decay.
messages: The PINc domain confers endonuclease activity and is expected to bind the catalytic metal ion.
messages: cytosol
messages: nucleolus
messages: telomere

8128:ppib
gene id: 8128:ppib
uniprot id: A0A669CTB8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:nagk
gene id: 8128:nagk
uniprot id: A0A669BLQ0
uniprot id: A0A669CY83
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

8128:dedd2
gene id: 8128:dedd2
uniprot id: A0A669B1K3
names: Subcellular Location Annotation
messages: nucleolus

8128:ndufa5
gene id: 8128:ndufa5
uniprot id: I3K9P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8128:oxa1l
gene id: 8128:oxa1l
uniprot id: I3JS94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

8128:LOC100710156
gene id: 8128:LOC100710156
uniprot id: A0A669BIC5
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:atp5po
gene id: 8128:atp5po
uniprot id: I3K590
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

8128:wdpcp
gene id: 8128:wdpcp
uniprot id: I3IYB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

8128:tmem161a
gene id: 8128:tmem161a
uniprot id: A0A669BAK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

8128:LOC109204437
gene id: 8128:LOC109204437
uniprot id: A0A669D599
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8128:sh3bp5
gene id: 8128:sh3bp5
uniprot id: A0A669CRY3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8128:tmed2
gene id: 8128:tmed2
uniprot id: A0A669CKU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8128:LOC100694809
gene id: 8128:LOC100694809
uniprot id: A0A669EWS6
names: Similarity
messages: Belongs to the MAGUK family.

8128:LOC100706079
gene id: 8128:LOC100706079
uniprot id: A0A669EFP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8128:pgls
gene id: 8128:pgls
uniprot id: I3J0J1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

8128:LOC100699994
gene id: 8128:LOC100699994
uniprot id: I3K1F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: cilium basal body

8128:rbl1
gene id: 8128:rbl1
uniprot id: I3JCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

8128:use1
gene id: 8128:use1
uniprot id: I3J097
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100695939
gene id: 8128:LOC100695939
uniprot id: I3JCV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8128:arglu1
gene id: 8128:arglu1
uniprot id: A0A669BQ12
names: Similarity
messages: Belongs to the UPF0430 family.

8128:LOC100692318
gene id: 8128:LOC100692318
uniprot id: A0A669B0W9
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100696975
gene id: 8128:LOC100696975
uniprot id: A0A669DV41
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8128:LOC100696293
gene id: 8128:LOC100696293
uniprot id: A0A669EVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100692771
gene id: 8128:LOC100692771
uniprot id: I3KZG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:tom1l2
gene id: 8128:tom1l2
uniprot id: A0A669E253
uniprot id: A0A669EBZ8
uniprot id: I3J1Z1
names: Similarity
messages: Belongs to the TOM1 family.

8128:ca6
gene id: 8128:ca6
uniprot id: A0A669AWX8
names: Caution
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:oprd1
gene id: 8128:oprd1
uniprot id: A0A669BYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:cep70
gene id: 8128:cep70
uniprot id: A0A669CC70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

8128:LOC100694023
gene id: 8128:LOC100694023
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:rnmt
gene id: 8128:rnmt
uniprot id: I3KDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

8128:LOC100690508
gene id: 8128:LOC100690508
uniprot id: A0A669CIC1
names: Similarity
messages: Belongs to the FAM131 family.

8128:ackr4
gene id: 8128:ackr4
uniprot id: I3KXB5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100699521
gene id: 8128:LOC100699521
uniprot id: I3KX63
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:LOC100703774
gene id: 8128:LOC100703774
uniprot id: A0A669DQ39
uniprot id: I3KUU5
names: Similarity
messages: Belongs to the globin family.

8128:LOC100696513
gene id: 8128:LOC100696513
uniprot id: A0A669FAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8128:LOC100702227
gene id: 8128:LOC100702227
uniprot id: A0A669F381
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:rab38
gene id: 8128:rab38
uniprot id: I3JC47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8128:LOC109194292
gene id: 8128:LOC109194292
uniprot id: I3JSH3
names: Caution
names: Cofactor
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100700669
gene id: 8128:LOC100700669
uniprot id: A0A669AZE9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:nudt15
gene id: 8128:nudt15
uniprot id: A0A669CZM6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

8128:nkd2
gene id: 8128:nkd2
uniprot id: A0A669C5H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

8128:LOC100710159
gene id: 8128:LOC100710159
uniprot id: I3J0C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:pus10
gene id: 8128:pus10
uniprot id: I3ITV4
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

8128:LOC100703296
gene id: 8128:LOC100703296
uniprot id: A0A669DXQ8
names: Similarity
messages: Belongs to the NXPE family.

8128:pih1d1
gene id: 8128:pih1d1
uniprot id: I3JH54
names: Similarity
messages: Belongs to the PIH1 family.

8128:LOC100691901
gene id: 8128:LOC100691901
uniprot id: A0A669E134
names: Similarity
messages: Belongs to the SUA5 family.

8128:ercc1
gene id: 8128:ercc1
uniprot id: I3J8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

8128:LOC100707529
gene id: 8128:LOC100707529
uniprot id: A0A669F9G6
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8128:LOC100706370
gene id: 8128:LOC100706370
uniprot id: A0A669CS94
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100704766
gene id: 8128:LOC100704766
uniprot id: I3K1S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:ildr2
gene id: 8128:ildr2
uniprot id: A0A669D847
uniprot id: I3K9M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8128:galnt15
gene id: 8128:galnt15
uniprot id: I3J9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100702079
gene id: 8128:LOC100702079
uniprot id: I3JE66
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8128:LOC109201604
gene id: 8128:LOC109201604
uniprot id: A0A669EBK8
names: Subcellular Location Annotation
messages: Cytoplasm

8128:poc5
gene id: 8128:poc5
uniprot id: I3KGR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

8128:pfkfb3
gene id: 8128:pfkfb3
uniprot id: A0A669E380
uniprot id: I3K1B8
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8128:LOC100690455
gene id: 8128:LOC100690455
uniprot id: A0A669BNZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

8128:sdf4
gene id: 8128:sdf4
uniprot id: I3KIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

8128:LOC100697446
gene id: 8128:LOC100697446
uniprot id: I3K6S4
names: Subcellular Location Annotation
messages: Nucleus

8128:slc1a4
gene id: 8128:slc1a4
uniprot id: A0A669EK30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8128:LOC100690615
gene id: 8128:LOC100690615
uniprot id: I3J5X3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100702583
gene id: 8128:LOC100702583
uniprot id: I3IVH3
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8128:parn
gene id: 8128:parn
uniprot id: I3IUA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm

8128:LOC100698638
gene id: 8128:LOC100698638
uniprot id: I3JW63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100709445
gene id: 8128:LOC100709445
uniprot id: A0A669D2I6
names: Similarity
messages: Belongs to the intercrine alpha (chemokine CxC) family.

8128:LOC100693377
gene id: 8128:LOC100693377
uniprot id: I3JQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm

8128:LOC100691573
gene id: 8128:LOC100691573
uniprot id: A0A669C9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8128:LOC100693372
gene id: 8128:LOC100693372
uniprot id: I3JJU0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8128:LOC100711811
gene id: 8128:LOC100711811
uniprot id: A0A669D0P6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100690129
gene id: 8128:LOC100690129
uniprot id: A0A669EVI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:crb2
gene id: 8128:crb2
uniprot id: I3KWI2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:senp6
gene id: 8128:senp6
uniprot id: I3KR54
names: Similarity
messages: Belongs to the peptidase C48 family.

8128:LOC100696563
gene id: 8128:LOC100696563
uniprot id: A0A669CCG3
names: Similarity
messages: Belongs to the PPP1R15 family.

8128:slc24a2
gene id: 8128:slc24a2
uniprot id: I3JQ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8128:LOC100706178
gene id: 8128:LOC100706178
uniprot id: I3IX63
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:unc93b1
gene id: 8128:unc93b1
uniprot id: A0A669CXW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

8128:LOC100692791
gene id: 8128:LOC100692791
uniprot id: I3JNK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:acaa2
gene id: 8128:acaa2
uniprot id: A0A669CUR8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8128:LOC100711486
gene id: 8128:LOC100711486
uniprot id: A0A669CRC4
names: Similarity
messages: Belongs to the LEM family.

8128:nr5a1
gene id: 8128:nr5a1
uniprot id: F6M7Z5
uniprot id: Q7ZT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

8128:clstn2
gene id: 8128:clstn2
uniprot id: A0A669C917
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

8128:gng10
gene id: 8128:gng10
uniprot id: I3JL47
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100699081
gene id: 8128:LOC100699081
uniprot id: I3JUX4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100697273
gene id: 8128:LOC100697273
uniprot id: A0A669DBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100700847
gene id: 8128:LOC100700847
uniprot id: A0A669DYS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100708184
gene id: 8128:LOC100708184
uniprot id: I3JKM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC102080309
gene id: 8128:LOC102080309
uniprot id: I3JIN4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:fam129a
gene id: 8128:fam129a
uniprot id: I3JLW7
names: Similarity
messages: Belongs to the Niban family.

8128:LOC100695752
gene id: 8128:LOC100695752
uniprot id: A0A669ENL8
names: Similarity
messages: Belongs to the TGF-beta family.

8128:pnpla6
gene id: 8128:pnpla6
uniprot id: A0A669ELB4
uniprot id: A0A669FBF8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:nkd1
gene id: 8128:nkd1
uniprot id: A0A669D2B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

8128:LOC102077979
gene id: 8128:LOC102077979
uniprot id: A0A669DJW3
names: Subcellular Location Annotation
messages: Membrane

8128:cpox
gene id: 8128:cpox
uniprot id: I3IZW5
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

8128:slc25a48
gene id: 8128:slc25a48
uniprot id: I3J951
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC102080895
gene id: 8128:LOC102080895
uniprot id: I3JKM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8128:LOC100709386
gene id: 8128:LOC100709386
uniprot id: I3JRW1
names: Similarity
messages: Belongs to the SNF7 family.

8128:LOC100690242
gene id: 8128:LOC100690242
uniprot id: A0A669BW09
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8128:gng4
gene id: 8128:gng4
uniprot id: I3J022
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:stk17a
gene id: 8128:stk17a
uniprot id: I3KD45
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC102080776
gene id: 8128:LOC102080776
uniprot id: A0A669DG37
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:mrpl53
gene id: 8128:mrpl53
uniprot id: I3J358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

8128:LOC100695640
gene id: 8128:LOC100695640
uniprot id: I3KYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

8128:amotl2
gene id: 8128:amotl2
uniprot id: I3KT59
names: Similarity
messages: Belongs to the angiomotin family.

8128:ndfip2
gene id: 8128:ndfip2
uniprot id: I3K270
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100706625
gene id: 8128:LOC100706625
uniprot id: A0A669BH10
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8128:LOC100692912
gene id: 8128:LOC100692912
uniprot id: A0A669D7H8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100701996
gene id: 8128:LOC100701996
uniprot id: I3J752
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:ppil2
gene id: 8128:ppil2
uniprot id: I3K9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

8128:ppp4r2
gene id: 8128:ppp4r2
uniprot id: A0A669EXQ7
names: Similarity
messages: Belongs to the PPP4R2 family.

8128:sbds
gene id: 8128:sbds
uniprot id: I3JEV5
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

8128:ddx28
gene id: 8128:ddx28
uniprot id: I3KXQ6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8128:hsd17b1
gene id: 8128:hsd17b1
uniprot id: Q49RB1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC109195020
gene id: 8128:LOC109195020
uniprot id: A0A669E292
names: Similarity
messages: Belongs to the peptidase S1B family.

8128:LOC100705337
gene id: 8128:LOC100705337
uniprot id: I3JL61
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100696284
gene id: 8128:LOC100696284
uniprot id: A0A669F5A0
names: Similarity
messages: Belongs to the S-100 family.

8128:LOC100711429
gene id: 8128:LOC100711429
uniprot id: I3KP96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8128:dus4l
gene id: 8128:dus4l
uniprot id: I3JBP1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

8128:gins4
gene id: 8128:gins4
uniprot id: I3JWY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

8128:rab3c
gene id: 8128:rab3c
uniprot id: A0A669C1P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

8128:uchl1
gene id: 8128:uchl1
uniprot id: Q8AV65
names: Similarity
messages: Belongs to the peptidase C12 family.

8128:LOC100709579
gene id: 8128:LOC100709579
uniprot id: I3KSE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

8128:LOC100710956
gene id: 8128:LOC100710956
uniprot id: A0A669C5T0
names: Similarity
messages: Belongs to the DNase II family.

8128:ltbp1
gene id: 8128:ltbp1
uniprot id: I3JZ27
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:chrm5
gene id: 8128:chrm5
uniprot id: B7SU46
uniprot id: I3L017
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8128:LOC100700789
gene id: 8128:LOC100700789
uniprot id: I3JTB1
names: Subcellular Location Annotation
messages: Nucleus

8128:insm1
gene id: 8128:insm1
uniprot id: I3KZL3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100693267
gene id: 8128:LOC100693267
uniprot id: A0A669CJW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:usp50
gene id: 8128:usp50
uniprot id: I3IUE7
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:LOC100701809
gene id: 8128:LOC100701809
uniprot id: A0A669BJ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8128:LOC100706951
gene id: 8128:LOC100706951
uniprot id: A0A669C880
uniprot id: A0A669DQP2
names: Similarity
messages: Belongs to the LDB family.

8128:tfip11
gene id: 8128:tfip11
uniprot id: I3K7S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
messages: Nucleus

8128:LOC100708012
gene id: 8128:LOC100708012
uniprot id: A0A669BW10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

8128:LOC106098437
gene id: 8128:LOC106098437
uniprot id: A0A669B9C8
names: Similarity
messages: Belongs to the SEC6 family.

8128:tubgcp6
gene id: 8128:tubgcp6
uniprot id: A0A669EII3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

8128:eef1akmt1
gene id: 8128:eef1akmt1
uniprot id: I3KF88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

8128:LOC100699230
gene id: 8128:LOC100699230
uniprot id: I3KBP0
names: Subcellular Location Annotation
messages: Membrane

8128:dnajc24
gene id: 8128:dnajc24
uniprot id: A0A669DJ95
names: Similarity
messages: Belongs to the DPH4 family.

8128:slc6a2
gene id: 8128:slc6a2
uniprot id: A0A669E5J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100700045
gene id: 8128:LOC100700045
uniprot id: I3KEX1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8128:cdk1
gene id: 8128:cdk1
uniprot id: I3JRM7
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:mmp28
gene id: 8128:mmp28
uniprot id: A0A669E806
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8128:LOC100696927
gene id: 8128:LOC100696927
uniprot id: I3KH15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:trove2
gene id: 8128:trove2
uniprot id: I3KQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

8128:mfsd10
gene id: 8128:mfsd10
uniprot id: I3KJR2
names: Subcellular Location Annotation
messages: Membrane

8128:csgalnact2
gene id: 8128:csgalnact2
uniprot id: I3JVS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8128:chrnd
gene id: 8128:chrnd
uniprot id: A0A669DMI1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:b9d2
gene id: 8128:b9d2
uniprot id: I3KX96
names: Subcellular Location Annotation
messages: cilium basal body

8128:LOC100698210
gene id: 8128:LOC100698210
uniprot id: A0A669C8R5
names: Similarity
messages: Belongs to the cyclin family.

8128:LOC100710608
gene id: 8128:LOC100710608
uniprot id: I3KBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:wnt6
gene id: 8128:wnt6
uniprot id: I3J9F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:sin3a
gene id: 8128:sin3a
uniprot id: I3K4X6
names: Subcellular Location Annotation
messages: Nucleus

8128:ino80d
gene id: 8128:ino80d
uniprot id: I3JPF6
names: Subcellular Location Annotation
messages: Nucleus

8128:rpl21
gene id: 8128:rpl21
uniprot id: I3K9H1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

8128:tbce
gene id: 8128:tbce
uniprot id: A0A669DCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

8128:lg14h19orf54
gene id: 8128:lg14h19orf54
uniprot id: I3J799
names: Similarity
messages: Belongs to the ACTMAP family.

8128:mgat1
gene id: 8128:mgat1
uniprot id: I3J1Q3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

8128:islr2
gene id: 8128:islr2
uniprot id: I3KYS6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC102077266
gene id: 8128:LOC102077266
uniprot id: A0A669BJ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8128:LOC100694183
gene id: 8128:LOC100694183
uniprot id: A0A669F500
names: Similarity
messages: Belongs to the actin family.

8128:LOC100695744
gene id: 8128:LOC100695744
uniprot id: I3KYL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:eif3j
gene id: 8128:eif3j
uniprot id: I3JG77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8128:LOC100701512
gene id: 8128:LOC100701512
uniprot id: A0A669CJF7
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8128:LOC100695466
gene id: 8128:LOC100695466
uniprot id: A0A669B3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

8128:ccs
gene id: 8128:ccs
uniprot id: A0A669DIP2
names: Similarity
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

8128:LOC100709384
gene id: 8128:LOC100709384
uniprot id: I3JTP4
names: Similarity
messages: Belongs to the TTC39 family.

8128:LOC100694986
gene id: 8128:LOC100694986
uniprot id: I3JEK1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

8128:vsx2
gene id: 8128:vsx2
uniprot id: I3K204
names: Subcellular Location Annotation
messages: Nucleus

8128:senp7
gene id: 8128:senp7
uniprot id: A0A669CE83
names: Similarity
messages: Belongs to the peptidase C48 family.

8128:LOC100712040
gene id: 8128:LOC100712040
uniprot id: I3K8D8
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8128:LOC100705161
gene id: 8128:LOC100705161
uniprot id: I3JHT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8128:anapc13
gene id: 8128:anapc13
uniprot id: A0A669BX13
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

8128:pyroxd1
gene id: 8128:pyroxd1
uniprot id: I3JU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

8128:ca12
gene id: 8128:ca12
uniprot id: I3KDY3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8128:LOC100694115
gene id: 8128:LOC100694115
uniprot id: A0A669BKP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:gart
gene id: 8128:gart
uniprot id: I3J0F6
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

8128:eno2
gene id: 8128:eno2
uniprot id: A0A669DUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

8128:LOC100706673
gene id: 8128:LOC100706673
uniprot id: I3JKZ3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm

8128:LOC100691502
gene id: 8128:LOC100691502
uniprot id: A0A669E6L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

8128:gys1
gene id: 8128:gys1
uniprot id: A0A669BG48
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

8128:LOC100698771
gene id: 8128:LOC100698771
uniprot id: I3JL55
names: Similarity
messages: Belongs to the CD36 family.

8128:nme6
gene id: 8128:nme6
uniprot id: A0A669E7S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8128:LOC100692578
gene id: 8128:LOC100692578
uniprot id: I3JW74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

8128:dpt
gene id: 8128:dpt
uniprot id: I3KT85
names: Similarity
messages: Belongs to the dermatopontin family.

8128:LOC100708067
gene id: 8128:LOC100708067
uniprot id: I3IYD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

8128:LOC100708293
gene id: 8128:LOC100708293
uniprot id: I3JXM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8128:dgke
gene id: 8128:dgke
uniprot id: A0A669DRP7
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8128:foxb2
gene id: 8128:foxb2
uniprot id: I3KYU6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100692841
gene id: 8128:LOC100692841
uniprot id: A0A669DVX1
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8128:LOC109198557
gene id: 8128:LOC109198557
uniprot id: A0A669C6I7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:LOC100704330
gene id: 8128:LOC100704330
uniprot id: A0A669B0T6
uniprot id: A0A669EXX6
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

8128:LOC100693392
gene id: 8128:LOC100693392
uniprot id: A0A669F7A1
uniprot id: I3JW87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8128:ncapd2
gene id: 8128:ncapd2
uniprot id: I3K540
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

8128:samd4a
gene id: 8128:samd4a
uniprot id: A0A669F6R0
uniprot id: I3JJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

8128:LOC100692441
gene id: 8128:LOC100692441
uniprot id: I3K864
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

8128:zdhhc9
gene id: 8128:zdhhc9
uniprot id: A0A669BZS8
uniprot id: A0A669C0M2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100710783
gene id: 8128:LOC100710783
uniprot id: A0A669DZL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

8128:LOC100698762
gene id: 8128:LOC100698762
uniprot id: I3KNL7
names: Similarity
messages: Belongs to the type II (or gamma) interferon family.

8128:cwc15
gene id: 8128:cwc15
uniprot id: A0A669DUK0
names: Similarity
messages: Belongs to the CWC15 family.

8128:nupr1
gene id: 8128:nupr1
uniprot id: A0A669C5N5
names: Similarity
messages: Belongs to the NUPR family.

8128:c5
gene id: 8128:c5
uniprot id: I3IW28
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100712060
gene id: 8128:LOC100712060
uniprot id: I3JTY5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100697594
gene id: 8128:LOC100697594
uniprot id: A0A669B4Q0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8128:LOC100701678
gene id: 8128:LOC100701678
uniprot id: I3IUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8128:xk
gene id: 8128:xk
uniprot id: A0A669DQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:slc39a9
gene id: 8128:slc39a9
uniprot id: I3KUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

8128:LOC100702285
gene id: 8128:LOC100702285
uniprot id: I3J0K8
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100697001
gene id: 8128:LOC100697001
uniprot id: A0A669B4P6
names: Similarity
messages: Belongs to the ATG8 family.

8128:dlx2
gene id: 8128:dlx2
uniprot id: A0A669EET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8128:LOC112841654
gene id: 8128:LOC112841654
uniprot id: A0A669BT73
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100709259
gene id: 8128:LOC100709259
uniprot id: I3JCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8128:LOC100701643
gene id: 8128:LOC100701643
uniprot id: I3JAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8128:sec31a
gene id: 8128:sec31a
uniprot id: A0A669CV96
uniprot id: A0A669D9V8
uniprot id: I3KE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

8128:LOC100706927
gene id: 8128:LOC100706927
uniprot id: I3K7E8
uniprot id: I3K7E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8128:sema6b
gene id: 8128:sema6b
uniprot id: A0A669DEI5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:tcp11l2
gene id: 8128:tcp11l2
uniprot id: I3JZU1
names: Similarity
messages: Belongs to the TCP11 family.

8128:LOC100705552
gene id: 8128:LOC100705552
uniprot id: I3JV88
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100698478
gene id: 8128:LOC100698478
uniprot id: I3K9C7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707130
gene id: 8128:LOC100707130
uniprot id: I3JI11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

8128:LOC100692172
gene id: 8128:LOC100692172
uniprot id: A0A669EHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

8128:trrap
gene id: 8128:trrap
uniprot id: A0A669EVQ1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

8128:LOC100710512
gene id: 8128:LOC100710512
uniprot id: I3KC34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

8128:LOC106098461
gene id: 8128:LOC106098461
uniprot id: A0A669DJS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC102078792
gene id: 8128:LOC102078792
uniprot id: I3JQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

8128:LOC100701739
gene id: 8128:LOC100701739
uniprot id: A0A669E7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

8128:polm
gene id: 8128:polm
uniprot id: A0A669BFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ).
messages: Nucleus

8128:rho
gene id: 8128:rho
uniprot id: I3KKS5
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

8128:rps20
gene id: 8128:rps20
uniprot id: A0A669BHU5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

8128:tmed10
gene id: 8128:tmed10
uniprot id: I3KDK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:atat1
gene id: 8128:atat1
uniprot id: A0A669BEV1
uniprot id: A0A669BQC7
uniprot id: A0A669CNB1
uniprot id: I3K0H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. May be involved in neuron development.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

8128:LOC100534562
gene id: 8128:LOC100534562
uniprot id: A0A669B7T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8128:plpp5
gene id: 8128:plpp5
uniprot id: A0A669BR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:LOC100694830
gene id: 8128:LOC100694830
uniprot id: I3JUJ5
names: Subcellular Location Annotation
messages: Membrane

8128:gpsm1
gene id: 8128:gpsm1
uniprot id: A0A669CVP5
uniprot id: I3KCM0
names: Similarity
messages: Belongs to the GPSM family.

8128:LOC100705428
gene id: 8128:LOC100705428
uniprot id: A0A669BWT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8128:stambpl1
gene id: 8128:stambpl1
uniprot id: I3KSI1
names: Similarity
messages: Belongs to the peptidase M67C family.

8128:LOC100710600
gene id: 8128:LOC100710600
uniprot id: A0A669E6R6
uniprot id: I3JM51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

8128:znf330
gene id: 8128:znf330
uniprot id: I3KLG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

8128:meox2
gene id: 8128:meox2
uniprot id: A0A669DRV0
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100695963
gene id: 8128:LOC100695963
uniprot id: I3J777
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100698458
gene id: 8128:LOC100698458
uniprot id: I3JGP9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:htr2b
gene id: 8128:htr2b
uniprot id: A0A669C8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

8128:leprotl1
gene id: 8128:leprotl1
uniprot id: I3IYX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

8128:bcorl1
gene id: 8128:bcorl1
uniprot id: I3J351
names: Similarity
messages: Belongs to the BCOR family.

8128:matk
gene id: 8128:matk
uniprot id: A0A669EYC7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:sigirr
gene id: 8128:sigirr
uniprot id: I3JNG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

8128:taf1
gene id: 8128:taf1
uniprot id: A0A669E2T9
uniprot id: I3J984
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

8128:LOC100695474
gene id: 8128:LOC100695474
uniprot id: I3K8J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

8128:LOC100697103
gene id: 8128:LOC100697103
uniprot id: A0A669ERN4
uniprot id: I3J9C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8128:LOC100701596
gene id: 8128:LOC100701596
uniprot id: I3KCX3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100701341
gene id: 8128:LOC100701341
uniprot id: I3JH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8128:LOC100694656
gene id: 8128:LOC100694656
uniprot id: A0A669E661
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:LOC100702950
gene id: 8128:LOC100702950
uniprot id: A0A669BKE0
uniprot id: A0A669CUA5
uniprot id: A0A669EPG1
uniprot id: A0A669EUF3
names: Subcellular Location Annotation
messages: Membrane

8128:vcp
gene id: 8128:vcp
uniprot id: I3K7U2
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:LOC100696891
gene id: 8128:LOC100696891
uniprot id: I3JAI1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709852
gene id: 8128:LOC100709852
uniprot id: I3J1Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8128:antxr2
gene id: 8128:antxr2
uniprot id: A0A669BMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8128:LOC100690321
gene id: 8128:LOC100690321
uniprot id: I3KIP0
names: Similarity
messages: Belongs to the BRINP family.

8128:acsf3
gene id: 8128:acsf3
uniprot id: A0A669DUD1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8128:rcan1
gene id: 8128:rcan1
uniprot id: A0A669B0G0
names: Similarity
messages: Belongs to the RCAN family.

8128:ndufa10
gene id: 8128:ndufa10
uniprot id: I3JVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

8128:nop10
gene id: 8128:nop10
uniprot id: A0A669CQ45
names: Similarity
messages: Belongs to the NOP10 family.

8128:spata18
gene id: 8128:spata18
uniprot id: I3J4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

8128:sh3pxd2a
gene id: 8128:sh3pxd2a
uniprot id: I3IV77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm

8128:LOC100708275
gene id: 8128:LOC100708275
uniprot id: I3KGT5
names: Similarity
messages: Belongs to the peptidase S51 family.

8128:laptm4b
gene id: 8128:laptm4b
uniprot id: I3KHV9
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

8128:LOC100690952
gene id: 8128:LOC100690952
uniprot id: A0A669E2F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8128:LOC100690541
gene id: 8128:LOC100690541
uniprot id: I3JNE8
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

8128:htr7
gene id: 8128:htr7
uniprot id: I3KEF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100691931
gene id: 8128:LOC100691931
uniprot id: A0A669E560
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100709859
gene id: 8128:LOC100709859
uniprot id: I3KSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:tm7sf2
gene id: 8128:tm7sf2
uniprot id: A0A669BEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

8128:cadm2
gene id: 8128:cadm2
uniprot id: A0A669F6G7
uniprot id: I3JAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nectin family.
messages: Membrane

8128:LOC100708196
gene id: 8128:LOC100708196
uniprot id: A0A669DRC1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

8128:srf
gene id: 8128:srf
uniprot id: I3JV84
uniprot id: I3JV85
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709964
gene id: 8128:LOC100709964
uniprot id: A0A669C4C8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:LOC100690103
gene id: 8128:LOC100690103
uniprot id: I3KT23
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Homotetramer.

8128:rack1
gene id: 8128:rack1
uniprot id: O42249
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
messages: Cytoplasm
messages: Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Required for VANGL2 membrane localization, inhibits Wnt signaling and regulates cellular polarization and oriented cell division during gastrulation (By similarity).

8128:LOC100707727
gene id: 8128:LOC100707727
uniprot id: A0A669C1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100693984
gene id: 8128:LOC100693984
uniprot id: A0A669CQN0
uniprot id: A0A669FAP8
names: Similarity
messages: Belongs to the peptidase C14A family.

8128:LOC100703490
gene id: 8128:LOC100703490
uniprot id: I3J314
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8128:riox1
gene id: 8128:riox1
uniprot id: A0A669B6X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

8128:LOC100695052
gene id: 8128:LOC100695052
uniprot id: A0A669EBY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

8128:dimt1
gene id: 8128:dimt1
uniprot id: A0A669EDK5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

8128:extl2
gene id: 8128:extl2
uniprot id: I3JUJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8128:eif1ax
gene id: 8128:eif1ax
uniprot id: A0A669ESL0
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.

8128:LOC100706253
gene id: 8128:LOC100706253
uniprot id: I3KGR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8128:thumpd3
gene id: 8128:thumpd3
uniprot id: I3KRZ7
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8128:mocos
gene id: 8128:mocos
uniprot id: A0A669CKF7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

8128:cmbl
gene id: 8128:cmbl
uniprot id: I3KAA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

8128:med28
gene id: 8128:med28
uniprot id: A0A669ENN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

8128:hnf1b
gene id: 8128:hnf1b
uniprot id: A0A669BVT1
uniprot id: A0A669E3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

8128:LOC100706096
gene id: 8128:LOC100706096
uniprot id: I3IWX9
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

8128:tpp1
gene id: 8128:tpp1
uniprot id: I3KW36
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100691860
gene id: 8128:LOC100691860
uniprot id: A0A669CXH2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8128:chrnb2
gene id: 8128:chrnb2
uniprot id: I3J3E4
uniprot id: I3JGD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100691481
gene id: 8128:LOC100691481
uniprot id: A0A669BB12
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8128:numb
gene id: 8128:numb
uniprot id: A0A669B4W7
uniprot id: I3IV49
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

8128:sema3a
gene id: 8128:sema3a
uniprot id: A0A669AWV4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ctsk
gene id: 8128:ctsk
uniprot id: A0A669CX17
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC100693082
gene id: 8128:LOC100693082
uniprot id: I3J615
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8128:copa
gene id: 8128:copa
uniprot id: I3KDA2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

8128:tmem150a
gene id: 8128:tmem150a
uniprot id: I3JYU8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100694874
gene id: 8128:LOC100694874
uniprot id: I3JKM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8128:LOC100692795
gene id: 8128:LOC100692795
uniprot id: A0A669ELZ5
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

8128:LOC100711088
gene id: 8128:LOC100711088
uniprot id: A0A669CE26
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:tmem98
gene id: 8128:tmem98
uniprot id: A0A669F8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

8128:coq9
gene id: 8128:coq9
uniprot id: I3JXY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

8128:ephb4
gene id: 8128:ephb4
uniprot id: A0A669B3T7
names: Subcellular Location Annotation
messages: Membrane

8128:cnrip1
gene id: 8128:cnrip1
uniprot id: I3IY43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

8128:LOC100692334
gene id: 8128:LOC100692334
uniprot id: A0A669BBX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

8128:tmprss5
gene id: 8128:tmprss5
uniprot id: A0A669BAK3
uniprot id: A0A669BT58
uniprot id: I3JYM8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:LOC106098085
gene id: 8128:LOC106098085
uniprot id: A0A669B540
uniprot id: I3IYT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

8128:fzd4
gene id: 8128:fzd4
uniprot id: I3JC44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8128:alox5
gene id: 8128:alox5
uniprot id: A0A669CRL1
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:usp33
gene id: 8128:usp33
uniprot id: A0A669DVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

8128:hddc2
gene id: 8128:hddc2
uniprot id: I3IW59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

8128:LOC100690880
gene id: 8128:LOC100690880
uniprot id: S4UUV5
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100700791
gene id: 8128:LOC100700791
uniprot id: A0A669DR92
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

8128:inpp1
gene id: 8128:inpp1
uniprot id: I3KT02
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8128:LOC100706094
gene id: 8128:LOC100706094
uniprot id: I3K5M1
names: Subcellular Location Annotation
messages: Membrane

8128:tmem9
gene id: 8128:tmem9
uniprot id: I3K287
names: Similarity
messages: Belongs to the TMEM9 family.

8128:LOC100710883
gene id: 8128:LOC100710883
uniprot id: A0A669CC39
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8128:LOC100699992
gene id: 8128:LOC100699992
uniprot id: I3K639
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

8128:LOC102079510
gene id: 8128:LOC102079510
uniprot id: I3KJB8
names: Subcellular Location Annotation
messages: Membrane

8128:rfx2
gene id: 8128:rfx2
uniprot id: A0A669BY59
uniprot id: I3JUT5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100695800
gene id: 8128:LOC100695800
uniprot id: I3JGE8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100710568
gene id: 8128:LOC100710568
uniprot id: A0A669CBW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Membrane

8128:LOC100692362
gene id: 8128:LOC100692362
uniprot id: I3JID1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

8128:LOC100690208
gene id: 8128:LOC100690208
uniprot id: A0A669F7X3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100698694
gene id: 8128:LOC100698694
uniprot id: I3KGQ8
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100698070
gene id: 8128:LOC100698070
uniprot id: I3KHE7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8128:LOC100706225
gene id: 8128:LOC100706225
uniprot id: A0A669DIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

8128:LOC100690878
gene id: 8128:LOC100690878
uniprot id: I3KI83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8128:LOC100706139
gene id: 8128:LOC100706139
uniprot id: I3J7B2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC109202501
gene id: 8128:LOC109202501
uniprot id: A0A669DZJ3
names: Subcellular Location Annotation
messages: Nucleus

8128:arhgef9
gene id: 8128:arhgef9
uniprot id: A0A669CRF4
uniprot id: I3KLV7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

8128:LOC100711618
gene id: 8128:LOC100711618
uniprot id: I3K977
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8128:LOC100704899
gene id: 8128:LOC100704899
uniprot id: A0A669CYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

8128:LOC100708444
gene id: 8128:LOC100708444
uniprot id: A0A669B010
names: Similarity
messages: Belongs to the SEC6 family.

8128:LOC100534433
gene id: 8128:LOC100534433
uniprot id: I3K7V7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8128:ino80
gene id: 8128:ino80
uniprot id: I3IWI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

8128:tmem168
gene id: 8128:tmem168
uniprot id: I3KJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane
messages: Nucleus membrane

8128:LOC100699852
gene id: 8128:LOC100699852
uniprot id: I3JP60
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100705007
gene id: 8128:LOC100705007
uniprot id: I3IWQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8128:uncx
gene id: 8128:uncx
uniprot id: A0A669D9S9
names: Subcellular Location Annotation
messages: Nucleus

8128:eef2kmt
gene id: 8128:eef2kmt
uniprot id: I3JSQ2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

8128:dapk2
gene id: 8128:dapk2
uniprot id: A0A669BJW0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:tpm1
gene id: 8128:tpm1
uniprot id: A0A669BV14
uniprot id: A0A669EPI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8128:c8b
gene id: 8128:c8b
uniprot id: H2EP76
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100690032
gene id: 8128:LOC100690032
uniprot id: I3J8D1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100701737
gene id: 8128:LOC100701737
uniprot id: I3K254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

8128:rab3ip
gene id: 8128:rab3ip
uniprot id: A0A669B1E6
uniprot id: A0A669BE58
uniprot id: I3KNG7
names: Similarity
messages: Belongs to the SEC2 family.

8128:LOC100690575
gene id: 8128:LOC100690575
uniprot id: A0A669CWZ4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100711599
gene id: 8128:LOC100711599
uniprot id: A0A669E641
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:spo11
gene id: 8128:spo11
uniprot id: I3KKI6
names: Similarity
messages: Belongs to the TOP6A family.

8128:LOC100706767
gene id: 8128:LOC100706767
uniprot id: I3JIY9
uniprot id: I3JIZ0
names: Similarity
messages: Belongs to the FAM131 family.

8128:LOC100705427
gene id: 8128:LOC100705427
uniprot id: I3JA87
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8128:LOC100699693
gene id: 8128:LOC100699693
uniprot id: A0A669DE62
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

8128:LOC100693741
gene id: 8128:LOC100693741
uniprot id: A0A669DEX8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709943
gene id: 8128:LOC100709943
uniprot id: A0A669FBK3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:LOC100534484
gene id: 8128:LOC100534484
uniprot id: I3IWW5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8128:LOC100695592
gene id: 8128:LOC100695592
uniprot id: A0A669C4W3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

8128:lg12h9orf78
gene id: 8128:lg12h9orf78
uniprot id: A0A669BF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TLS1 family.
messages: Nucleus

8128:LOC100690134
gene id: 8128:LOC100690134
uniprot id: I3KZ76
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:ncor1
gene id: 8128:ncor1
uniprot id: I3K4U8
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

8128:cplane2
gene id: 8128:cplane2
uniprot id: A0A669ER79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

8128:LOC100707837
gene id: 8128:LOC100707837
uniprot id: I3JJ26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100689844
gene id: 8128:LOC100689844
uniprot id: A0A669BJD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

8128:tdp2
gene id: 8128:tdp2
uniprot id: I3J2Z9
names: Subcellular Location Annotation
messages: PML body

8128:nadk2
gene id: 8128:nadk2
uniprot id: I3JZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

8128:camk1d
gene id: 8128:camk1d
uniprot id: A0A669B0Y2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100706047
gene id: 8128:LOC100706047
uniprot id: A0A669ENI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:esrrg
gene id: 8128:esrrg
uniprot id: I3KKJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8128:ubr1
gene id: 8128:ubr1
uniprot id: I3KW88
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

8128:amdhd1
gene id: 8128:amdhd1
uniprot id: A0A669AVQ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

8128:LOC100534567
gene id: 8128:LOC100534567
uniprot id: B7SU44
uniprot id: I3KBW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8128:rin2
gene id: 8128:rin2
uniprot id: A0A669B512
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

8128:pla2g12a
gene id: 8128:pla2g12a
uniprot id: I3KLR2
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100711003
gene id: 8128:LOC100711003
uniprot id: A0A669DH35
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:LOC100690783
gene id: 8128:LOC100690783
uniprot id: A0A669DVN8
uniprot id: A0A669EUA3
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

8128:LOC100707598
gene id: 8128:LOC100707598
uniprot id: I3J224
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100690378
gene id: 8128:LOC100690378
uniprot id: A0A669DJN1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100712188
gene id: 8128:LOC100712188
uniprot id: I3J8A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

8128:LOC109196579
gene id: 8128:LOC109196579
uniprot id: A0A669BX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:actr5
gene id: 8128:actr5
uniprot id: I3J0R2
names: Similarity
messages: Belongs to the actin family.

8128:mras
gene id: 8128:mras
uniprot id: I3J9R0
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:ncapg
gene id: 8128:ncapg
uniprot id: I3JR78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

8128:LOC100698542
gene id: 8128:LOC100698542
uniprot id: I3K7L5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8128:LOC100700643
gene id: 8128:LOC100700643
uniprot id: I3JYC5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC109200453
gene id: 8128:LOC109200453
uniprot id: A0A669B4U4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

8128:LOC100691005
gene id: 8128:LOC100691005
uniprot id: I3JC53
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

8128:LOC100711225
gene id: 8128:LOC100711225
uniprot id: I3JKE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

8128:LOC100697881
gene id: 8128:LOC100697881
uniprot id: A0A669B0A4
uniprot id: A0A669D2J8
names: Subcellular Location Annotation
messages: ruffle membrane

8128:tmem161b
gene id: 8128:tmem161b
uniprot id: A0A669F4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

8128:LOC106097720
gene id: 8128:LOC106097720
uniprot id: A0A669BNR8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100711208
gene id: 8128:LOC100711208
uniprot id: I3K2G4
names: Similarity
messages: Belongs to the peptidase M24 family.

8128:LOC100693177
gene id: 8128:LOC100693177
uniprot id: I3JHU4
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8128:LOC100699683
gene id: 8128:LOC100699683
uniprot id: A0A669CCS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8128:LOC102083227
gene id: 8128:LOC102083227
uniprot id: I3JBM7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100703628
gene id: 8128:LOC100703628
uniprot id: I3KIU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

8128:LOC100695618
gene id: 8128:LOC100695618
uniprot id: I3IYZ9
names: Similarity
messages: Belongs to the ependymin family.

8128:gal3st3
gene id: 8128:gal3st3
uniprot id: I3K5J3
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8128:LOC100707058
gene id: 8128:LOC100707058
uniprot id: I3KV01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100701309
gene id: 8128:LOC100701309
uniprot id: I3JLV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8128:LOC100693618
gene id: 8128:LOC100693618
uniprot id: I3J624
names: Subcellular Location Annotation
messages: Cytoplasm

8128:camk2n2
gene id: 8128:camk2n2
uniprot id: I3JUX3
names: Similarity
messages: Belongs to the CAMK2N family.

8128:LOC100711741
gene id: 8128:LOC100711741
uniprot id: I3J2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8128:LOC100711647
gene id: 8128:LOC100711647
uniprot id: A0A669E5D9
uniprot id: I3J876
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:rhbdl1
gene id: 8128:rhbdl1
uniprot id: I3KVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

8128:dgkb
gene id: 8128:dgkb
uniprot id: A0A669BB72
uniprot id: I3JHD4
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8128:cpb1
gene id: 8128:cpb1
uniprot id: I3JEU4
names: Similarity
messages: Belongs to the peptidase M14 family.

8128:rpl7a
gene id: 8128:rpl7a
uniprot id: A0A669BQF4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

8128:rad23a
gene id: 8128:rad23a
uniprot id: I3JHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

8128:prdm13
gene id: 8128:prdm13
uniprot id: I3IU48
names: Subcellular Location Annotation
messages: Nucleus

8128:tmem115
gene id: 8128:tmem115
uniprot id: A0A669D8C0
names: Subcellular Location Annotation
messages: Membrane

8128:neto2
gene id: 8128:neto2
uniprot id: I3J4Z6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:pih1d3
gene id: 8128:pih1d3
uniprot id: I3KCZ9
names: Similarity
messages: Belongs to the PIH1 family.

8128:LOC100689836
gene id: 8128:LOC100689836
uniprot id: I3J3G0
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:nat9
gene id: 8128:nat9
uniprot id: I3JMK6
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

8128:LOC100707385
gene id: 8128:LOC100707385
uniprot id: I3KQK0
names: Similarity
messages: Belongs to the BRINP family.

8128:mrps16
gene id: 8128:mrps16
uniprot id: I3KA09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

8128:eya1
gene id: 8128:eya1
uniprot id: A0A669F9Y1
uniprot id: I3K9Z5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

8128:becn1
gene id: 8128:becn1
uniprot id: I3KHG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beclin family.
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: autophagosome
messages: trans-Golgi network membrane

8128:LOC100711830
gene id: 8128:LOC100711830
uniprot id: I3J7N1
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:LOC100705374
gene id: 8128:LOC100705374
uniprot id: I3JK69
names: Similarity
messages: Belongs to the CD99 family.

8128:LOC102081136
gene id: 8128:LOC102081136
uniprot id: A0A669FB62
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100712136
gene id: 8128:LOC100712136
uniprot id: A0A669CPQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:glrx
gene id: 8128:glrx
uniprot id: A0A669DPR4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

8128:il17re
gene id: 8128:il17re
uniprot id: A0A669E9Q7
names: Subcellular Location Annotation
messages: Membrane

8128:shpk
gene id: 8128:shpk
uniprot id: I3K4S5
names: Similarity
messages: Belongs to the FGGY kinase family.

8128:pfdn2
gene id: 8128:pfdn2
uniprot id: A0A669ER69
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

8128:LOC100699672
gene id: 8128:LOC100699672
uniprot id: A0A669C7P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8128:tp53bp2
gene id: 8128:tp53bp2
uniprot id: I3KQ41
uniprot id: I3KQ42
names: Subcellular Location Annotation
messages: Nucleus

8128:granulin
gene id: 8128:granulin
uniprot id: C7E2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8128:smarcad1
gene id: 8128:smarcad1
uniprot id: I3KCW1
names: Subcellular Location Annotation
messages: Chromosome

8128:cmtm4
gene id: 8128:cmtm4
uniprot id: A0A669DAR1
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707472
gene id: 8128:LOC100707472
uniprot id: I3KLC9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8128:LOC100697574
gene id: 8128:LOC100697574
uniprot id: I3KVR7
names: Subcellular Location Annotation
messages: Membrane

8128:cdipt
gene id: 8128:cdipt
uniprot id: I3JSH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

8128:LOC100705848
gene id: 8128:LOC100705848
uniprot id: I3JBX5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100698051
gene id: 8128:LOC100698051
uniprot id: I3J5X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8128:LOC100711347
gene id: 8128:LOC100711347
uniprot id: I3IZZ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:setd3
gene id: 8128:setd3
uniprot id: I3JYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

8128:rsrp1
gene id: 8128:rsrp1
uniprot id: I3JN98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSRP family.
messages: Nucleus
messages: Probably acts as a spliceosomal factor that contributes to spliceosome assembly and regulates the isoform switching of proteins such as PARP6.

8128:LOC100690806
gene id: 8128:LOC100690806
uniprot id: I3KRV5
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

8128:ciapin1
gene id: 8128:ciapin1
uniprot id: A0A669EE21
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

8128:LOC100695905
gene id: 8128:LOC100695905
uniprot id: A0A669CXA7
names: Similarity
messages: Belongs to the PACS family.

8128:LOC100691763
gene id: 8128:LOC100691763
uniprot id: I3J5T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8128:tmem47
gene id: 8128:tmem47
uniprot id: I3IZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8128:dbx1
gene id: 8128:dbx1
uniprot id: I3JJG6
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709287
gene id: 8128:LOC100709287
uniprot id: I3KL70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8128:LOC100696371
gene id: 8128:LOC100696371
uniprot id: I3KH53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8128:LOC100696710
gene id: 8128:LOC100696710
uniprot id: I3J1H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

8128:LOC100711975
gene id: 8128:LOC100711975
uniprot id: I3JVS6
names: Subcellular Location Annotation
messages: Membrane

8128:cops8
gene id: 8128:cops8
uniprot id: I3JLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

8128:LOC102077512
gene id: 8128:LOC102077512
uniprot id: A0A669ERT6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:edil3
gene id: 8128:edil3
uniprot id: A0A669DKA2
uniprot id: A0A669ESL5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100693807
gene id: 8128:LOC100693807
uniprot id: I3KAK5
names: Similarity
messages: Belongs to the peptidase M17 family.

8128:LOC100703257
gene id: 8128:LOC100703257
uniprot id: I3JPF4
names: Similarity
messages: Belongs to the filamin family.

8128:LOC100711030
gene id: 8128:LOC100711030
uniprot id: A0A669DXC5
names: Similarity
messages: Belongs to the TAFA family.

8128:LOC102079196
gene id: 8128:LOC102079196
uniprot id: I3KIC3
names: Similarity
messages: Belongs to the Niban family.

8128:LOC100704063
gene id: 8128:LOC100704063
uniprot id: I3JPT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8128:dync2li1
gene id: 8128:dync2li1
uniprot id: I3IX02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

8128:LOC100709513
gene id: 8128:LOC100709513
uniprot id: I3J4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC102079944
gene id: 8128:LOC102079944
uniprot id: A0A669B388
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

8128:LOC100690518
gene id: 8128:LOC100690518
uniprot id: I3KJ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:mrpl20
gene id: 8128:mrpl20
uniprot id: I3KRS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

8128:LOC100703120
gene id: 8128:LOC100703120
uniprot id: A0A669EX82
names: Subcellular Location Annotation
messages: Membrane

8128:tatdn1
gene id: 8128:tatdn1
uniprot id: A0A669EJY8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8128:b3gnt9
gene id: 8128:b3gnt9
uniprot id: I3JVB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:vps41
gene id: 8128:vps41
uniprot id: A0A669BQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

8128:LOC100699984
gene id: 8128:LOC100699984
uniprot id: I3KLC6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

8128:LOC100699330
gene id: 8128:LOC100699330
uniprot id: A0A669DR25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:LOC100705478
gene id: 8128:LOC100705478
uniprot id: I3JU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

8128:prkaa1
gene id: 8128:prkaa1
uniprot id: A0A0M4G4N9
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

8128:LOC102082801
gene id: 8128:LOC102082801
uniprot id: A0A669EI67
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

8128:LOC100711230
gene id: 8128:LOC100711230
uniprot id: A0A669CZW6
names: Subcellular Location Annotation
messages: ruffle membrane

8128:LOC100710589
gene id: 8128:LOC100710589
uniprot id: A0A669CS42
names: Similarity
messages: Belongs to the YOS1 family.

8128:cdpf1
gene id: 8128:cdpf1
uniprot id: A0A669D4F6
names: Similarity
messages: Belongs to the CDPF1 family.

8128:opn1sw
gene id: 8128:opn1sw
uniprot id: F8TJW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8128:pknox1
gene id: 8128:pknox1
uniprot id: I3KLH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

8128:stn1
gene id: 8128:stn1
uniprot id: I3JQS4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

8128:calcb
gene id: 8128:calcb
uniprot id: A0A669BUL3
uniprot id: I3KEK3
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

8128:ppp2ca
gene id: 8128:ppp2ca
uniprot id: I3KKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8128:LOC100702196
gene id: 8128:LOC100702196
uniprot id: A0A669CSG5
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:rtn1
gene id: 8128:rtn1
uniprot id: A0A669ECE7
uniprot id: I3KW57
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100695566
gene id: 8128:LOC100695566
uniprot id: I3K2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8128:LOC100703709
gene id: 8128:LOC100703709
uniprot id: A0A669DP12
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8128:mccc2
gene id: 8128:mccc2
uniprot id: A0A669BL41
names: Similarity
messages: Belongs to the AccD/PCCB family.

8128:LOC100705570
gene id: 8128:LOC100705570
uniprot id: I3JTC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

8128:LOC100690268
gene id: 8128:LOC100690268
uniprot id: A0A669C9S2
uniprot id: I3KHY6
names: Similarity
messages: Belongs to the MAGUK family.

8128:LOC102077535
gene id: 8128:LOC102077535
uniprot id: A0A669AW33
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100692992
gene id: 8128:LOC100692992
uniprot id: I3IYV1
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8128:tysnd1
gene id: 8128:tysnd1
uniprot id: I3KQA8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

8128:LOC100697344
gene id: 8128:LOC100697344
uniprot id: I3K3F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8128:LOC100696561
gene id: 8128:LOC100696561
uniprot id: I3J6Z8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

8128:LOC100712554
gene id: 8128:LOC100712554
uniprot id: I3KN04
names: Subcellular Location Annotation
messages: cytoskeleton

8128:psmf1
gene id: 8128:psmf1
uniprot id: I3JCK5
names: Similarity
messages: Belongs to the proteasome inhibitor PI31 family.

8128:slc30a9
gene id: 8128:slc30a9
uniprot id: I3J295
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

8128:LOC100694900
gene id: 8128:LOC100694900
uniprot id: I3J926
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

8128:LOC100697719
gene id: 8128:LOC100697719
uniprot id: A0A669ERD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100709787
gene id: 8128:LOC100709787
uniprot id: I3JR49
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:gatm
gene id: 8128:gatm
uniprot id: I3IUG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development.
messages: Homodimer.
messages: Mitochondrion inner membrane

8128:rrp7a
gene id: 8128:rrp7a
uniprot id: I3JNS3
names: Similarity
messages: Belongs to the RRP7 family.

8128:LOC100697173
gene id: 8128:LOC100697173
uniprot id: I3KQ87
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100706898
gene id: 8128:LOC100706898
uniprot id: I3K5N5
names: Subcellular Location Annotation
messages: Membrane

8128:rasgrp1
gene id: 8128:rasgrp1
uniprot id: A0A669D3X8
names: Similarity
messages: Belongs to the RASGRP family.

8128:scube3
gene id: 8128:scube3
uniprot id: I3KJY2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:rpl15
gene id: 8128:rpl15
uniprot id: I3JVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: Cytoplasm

8128:LOC100700608
gene id: 8128:LOC100700608
uniprot id: I3JWV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

8128:upp2
gene id: 8128:upp2
uniprot id: I3JQW6
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

8128:glce
gene id: 8128:glce
uniprot id: I3K685
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

8128:nudc
gene id: 8128:nudc
uniprot id: A0A669DZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

8128:csta
gene id: 8128:csta
uniprot id: I3JEH7
names: Similarity
messages: Belongs to the cystatin family.

8128:LOC100706516
gene id: 8128:LOC100706516
uniprot id: A0A669EST8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8128:prrx1
gene id: 8128:prrx1
uniprot id: I3JLZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:LOC100711295
gene id: 8128:LOC100711295
uniprot id: A0A669BG49
uniprot id: A0A669F152
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:tmem8b
gene id: 8128:tmem8b
uniprot id: I3KJX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

8128:LOC100697215
gene id: 8128:LOC100697215
uniprot id: A0A669DEN0
names: Similarity
messages: Belongs to the arrestin family.

8128:heatr5a
gene id: 8128:heatr5a
uniprot id: I3J0L1
uniprot id: I3J0L2
names: Similarity
messages: Belongs to the HEATR5 family.

8128:tmem35a
gene id: 8128:tmem35a
uniprot id: A0A669DAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

8128:p2ry8
gene id: 8128:p2ry8
uniprot id: I3JIB4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:tdrd7
gene id: 8128:tdrd7
uniprot id: A0A669DAQ8
uniprot id: I3KVE2
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100690413
gene id: 8128:LOC100690413
uniprot id: I3J9N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus
messages: telomere

8128:LOC100708948
gene id: 8128:LOC100708948
uniprot id: A0A669F350
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:sept5
gene id: 8128:sept5
uniprot id: A0A669DGK0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:LOC109194311
gene id: 8128:LOC109194311
uniprot id: I3KPR1
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

8128:ptk7
gene id: 8128:ptk7
uniprot id: I3JV77
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons.
messages: Cell membrane
messages: Interacts with plexA; component of a receptor complex that mediates the repulsive signaling in response to Semaphorin ligands.
messages: Membrane

8128:cdk5r1
gene id: 8128:cdk5r1
uniprot id: I3KPC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

8128:arl2bp
gene id: 8128:arl2bp
uniprot id: I3JVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
messages: centrosome
messages: cilium basal body

8128:LOC100695523
gene id: 8128:LOC100695523
uniprot id: I3JWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:phf5a
gene id: 8128:phf5a
uniprot id: A0A669D3P6
names: Similarity
messages: Belongs to the PHF5 family.

8128:jam2
gene id: 8128:jam2
uniprot id: A0A669B7T7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693079
gene id: 8128:LOC100693079
uniprot id: A0A669DRR5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:LOC100692232
gene id: 8128:LOC100692232
uniprot id: A0A669FAK5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690211
gene id: 8128:LOC100690211
uniprot id: I3KQ81
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8128:LOC100712275
gene id: 8128:LOC100712275
uniprot id: A0A669BTR1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100700721
gene id: 8128:LOC100700721
uniprot id: A0A669DXD8
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100692610
gene id: 8128:LOC100692610
uniprot id: I3IYI5
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

8128:LOC109200188
gene id: 8128:LOC109200188
uniprot id: A0A669ETL1
names: Similarity
messages: Belongs to the HARBI1 family.

8128:aste1
gene id: 8128:aste1
uniprot id: I3J106
names: Similarity
messages: Belongs to the asteroid family.

8128:LOC102081219
gene id: 8128:LOC102081219
uniprot id: I3JDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

8128:cyhr1
gene id: 8128:cyhr1
uniprot id: I3J200
names: Similarity
messages: Belongs to the ZFTRAF1 family.

8128:LOC100709091
gene id: 8128:LOC100709091
uniprot id: A0A669DAF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:LOC102083201
gene id: 8128:LOC102083201
uniprot id: I3JQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8128:LOC100694214
gene id: 8128:LOC100694214
uniprot id: I3J2H9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100707988
gene id: 8128:LOC100707988
uniprot id: A0A669EA80
uniprot id: I3KBL4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:clp1
gene id: 8128:clp1
uniprot id: I3JC09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

8128:hoxb9
gene id: 8128:hoxb9
uniprot id: I3JFZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:vps33b
gene id: 8128:vps33b
uniprot id: I3JIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8128:LOC102081650
gene id: 8128:LOC102081650
uniprot id: I3KJS8
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100691542
gene id: 8128:LOC100691542
uniprot id: A0A669CK88
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8128:LOC100707634
gene id: 8128:LOC100707634
uniprot id: A0A669D7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8128:shmt1
gene id: 8128:shmt1
uniprot id: A0A669F0I3
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

8128:LOC100709917
gene id: 8128:LOC100709917
uniprot id: I3KJN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

8128:rhpn2
gene id: 8128:rhpn2
uniprot id: A0A669DJ65
names: Similarity
messages: Belongs to the RHPN family.

8128:hsd17b12
gene id: 8128:hsd17b12
uniprot id: I3KET1
uniprot id: Q49RB0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC112841638
gene id: 8128:LOC112841638
uniprot id: I3KGZ3
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8128:LOC100690921
gene id: 8128:LOC100690921
uniprot id: I3K360
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100705318
gene id: 8128:LOC100705318
uniprot id: A0A669DDF2
names: Subcellular Location Annotation
messages: Cytoplasm

8128:upf3a
gene id: 8128:upf3a
uniprot id: I3JIA9
names: Similarity
messages: Belongs to the RENT3 family.

8128:dnm2
gene id: 8128:dnm2
uniprot id: A0A669F928
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8128:LOC100711257
gene id: 8128:LOC100711257
uniprot id: A0A669BXX5
uniprot id: A0A669E8E6
uniprot id: I3KTZ5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100694195
gene id: 8128:LOC100694195
uniprot id: A0A669DC51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

8128:ptgir
gene id: 8128:ptgir
uniprot id: I3JF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100709240
gene id: 8128:LOC100709240
uniprot id: A0A669F6I6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690424
gene id: 8128:LOC100690424
uniprot id: A0A669D6P3
uniprot id: I3JVZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:triqk
gene id: 8128:triqk
uniprot id: A0A669CYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:ift57
gene id: 8128:ift57
uniprot id: I3K385
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

8128:LOC100705513
gene id: 8128:LOC100705513
uniprot id: I3JGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100693040
gene id: 8128:LOC100693040
uniprot id: A0A669C2P3
uniprot id: I3JMY6
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8128:LOC100703715
gene id: 8128:LOC100703715
uniprot id: A0A669CS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100704578
gene id: 8128:LOC100704578
uniprot id: I3KVZ5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8128:u2af2
gene id: 8128:u2af2
uniprot id: A0A669E5U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

8128:LOC100699117
gene id: 8128:LOC100699117
uniprot id: I3JYG0
names: Subcellular Location Annotation
messages: Membrane

8128:nagpa
gene id: 8128:nagpa
uniprot id: I3IZ42
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:eif4ebp2
gene id: 8128:eif4ebp2
uniprot id: I3KQB4
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8128:gss
gene id: 8128:gss
uniprot id: A0A669CFS7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

8128:dolk
gene id: 8128:dolk
uniprot id: I3JKC1
names: Similarity
messages: Belongs to the polyprenol kinase family.

8128:ndufs1
gene id: 8128:ndufs1
uniprot id: I3JPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

8128:lbr
gene id: 8128:lbr
uniprot id: I3JZS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus inner membrane

8128:LOC100698717
gene id: 8128:LOC100698717
uniprot id: I3JTJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

8128:LOC100702854
gene id: 8128:LOC100702854
uniprot id: I3KRY7
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:ptprb
gene id: 8128:ptprb
uniprot id: A0A669DBD1
uniprot id: I3KPG2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

8128:LOC102082099
gene id: 8128:LOC102082099
uniprot id: A0A669BF50
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693506
gene id: 8128:LOC100693506
uniprot id: A0A669CIR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8128:LOC109194559
gene id: 8128:LOC109194559
uniprot id: A0A669ETE4
names: Function
names: Similarity
names: Subunit
messages: Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
messages: Belongs to the fucolectin family.
messages: Homotrimer.

8128:bcas2
gene id: 8128:bcas2
uniprot id: I3JRW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

8128:LOC100707304
gene id: 8128:LOC100707304
uniprot id: I3JJ09
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100695221
gene id: 8128:LOC100695221
uniprot id: A0A669F9X7
names: Function
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein (By similarity). The carboxylated form binds strongly to apatite and calcium.

8128:dennd6a
gene id: 8128:dennd6a
uniprot id: I3J9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

8128:ube4b
gene id: 8128:ube4b
uniprot id: I3J264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

8128:LOC100696524
gene id: 8128:LOC100696524
uniprot id: A0A669DG48
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

8128:LOC100695840
gene id: 8128:LOC100695840
uniprot id: I3KNF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100695167
gene id: 8128:LOC100695167
uniprot id: I3KMF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:KEH09 p04
gene id: 8128:KEH09_p04
uniprot id: D2KP33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

8128:LOC100708913
gene id: 8128:LOC100708913
uniprot id: I3KJD5
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8128:b3gat2
gene id: 8128:b3gat2
uniprot id: A0A669AXB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:gdf3
gene id: 8128:gdf3
uniprot id: I3KKA7
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC100699569
gene id: 8128:LOC100699569
uniprot id: A0A669CN94
uniprot id: I3JFK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.

8128:LOC100690937
gene id: 8128:LOC100690937
uniprot id: A0A669BAQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8128:LOC100691361
gene id: 8128:LOC100691361
uniprot id: A0A669ESD9
uniprot id: I3KMN5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ttc26
gene id: 8128:ttc26
uniprot id: I3KPB5
names: Similarity
messages: Belongs to the IFT56 family.

8128:psmc5
gene id: 8128:psmc5
uniprot id: A0A669ELL2
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:LOC100689723
gene id: 8128:LOC100689723
uniprot id: I3K5K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8128:LOC100712429
gene id: 8128:LOC100712429
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:LOC106098467
gene id: 8128:LOC106098467
uniprot id: A0A669D6W8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC109197513
gene id: 8128:LOC109197513
uniprot id: A0A669C8F3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100691082
gene id: 8128:LOC100691082
uniprot id: A0A669EBM3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8128:LOC100690753
gene id: 8128:LOC100690753
uniprot id: I3KQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:LOC100700842
gene id: 8128:LOC100700842
uniprot id: A0A669DD41
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:dyrk1a
gene id: 8128:dyrk1a
uniprot id: A0A669DJK8
uniprot id: A0A669F8G8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8128:LOC100691685
gene id: 8128:LOC100691685
uniprot id: I3KKU2
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF168 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

8128:hvcn1
gene id: 8128:hvcn1
uniprot id: I3K0G4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

8128:LOC100704199
gene id: 8128:LOC100704199
uniprot id: I3L005
names: Subcellular Location Annotation
messages: Membrane

8128:pard3
gene id: 8128:pard3
uniprot id: I3J6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

8128:LOC100708378
gene id: 8128:LOC100708378
uniprot id: I3KQK6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100701281
gene id: 8128:LOC100701281
uniprot id: I3KD85
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100703901
gene id: 8128:LOC100703901
uniprot id: A0A669E5N6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100697286
gene id: 8128:LOC100697286
uniprot id: A0A669DY51
uniprot id: A0A669EWG5
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

8128:ssbp2
gene id: 8128:ssbp2
uniprot id: A0A669EVQ2
names: Subcellular Location Annotation
messages: Nucleus

8128:rexo4
gene id: 8128:rexo4
uniprot id: I3KVW1
names: Similarity
messages: Belongs to the REXO4 family.

8128:asic4
gene id: 8128:asic4
uniprot id: A0A669F561
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Cell membrane
messages: Membrane

8128:dars
gene id: 8128:dars
uniprot id: I3J9K3
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

8128:LOC109196048
gene id: 8128:LOC109196048
uniprot id: I3KZY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

8128:LOC100704992
gene id: 8128:LOC100704992
uniprot id: I3KBH9
names: Similarity
messages: Belongs to the TAFA family.

8128:cwf19l1
gene id: 8128:cwf19l1
uniprot id: A0A669BAZ6
names: Similarity
messages: Belongs to the CWF19 family.

8128:LOC100705190
gene id: 8128:LOC100705190
uniprot id: A0A669F7Y2
names: Similarity
messages: Belongs to the ANKRD34 family.

8128:LOC106097998
gene id: 8128:LOC106097998
uniprot id: A0A669DWI5
names: Similarity
messages: Belongs to the Bcl-2 family.

8128:adcy2
gene id: 8128:adcy2
uniprot id: A0A669D0K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8128:cpsf6
gene id: 8128:cpsf6
uniprot id: I3K0U0
uniprot id: I3K0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

8128:ano8
gene id: 8128:ano8
uniprot id: I3JV24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:rfx1
gene id: 8128:rfx1
uniprot id: A0A669B865
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100703583
gene id: 8128:LOC100703583
uniprot id: A0A669CBB8
uniprot id: I3JWL7
names: Similarity
messages: Belongs to the uridine kinase family.

8128:LOC100712094
gene id: 8128:LOC100712094
uniprot id: I3KAM8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:slc30a4
gene id: 8128:slc30a4
uniprot id: I3K6K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8128:LOC100698355
gene id: 8128:LOC100698355
uniprot id: A0A669E177
names: Similarity
messages: Belongs to the SPIN/STSY family.

8128:LOC102075590
gene id: 8128:LOC102075590
uniprot id: I3L031
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:st3gal4
gene id: 8128:st3gal4
uniprot id: A0A669BV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:lg3h20orf27
gene id: 8128:lg3h20orf27
uniprot id: A0A669BHW5
names: Similarity
messages: Belongs to the ADISSP family.

8128:adck5
gene id: 8128:adck5
uniprot id: I3JLE0
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8128:vwc2
gene id: 8128:vwc2
uniprot id: I3JVZ7
names: Subcellular Location Annotation
messages: Synapse

8128:gsdme
gene id: 8128:gsdme
uniprot id: I3J4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

8128:slc12a3
gene id: 8128:slc12a3
uniprot id: I3JX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:LOC100700508
gene id: 8128:LOC100700508
uniprot id: I3K838
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:atp7a
gene id: 8128:atp7a
uniprot id: F5C7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

8128:zc3hc1
gene id: 8128:zc3hc1
uniprot id: I3K0L3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100707418
gene id: 8128:LOC100707418
uniprot id: A0A669CYQ2
uniprot id: A0A669E2B0
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

8128:LOC100706920
gene id: 8128:LOC100706920
uniprot id: A0A669C8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8128:mogs
gene id: 8128:mogs
uniprot id: I3KLY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

8128:atp5f1d
gene id: 8128:atp5f1d
uniprot id: A0A669DIH2
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

8128:LOC100710529
gene id: 8128:LOC100710529
uniprot id: A0A669CXG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

8128:npepl1
gene id: 8128:npepl1
uniprot id: A0A669DZ18
names: Similarity
messages: Belongs to the peptidase M17 family.

8128:LOC100690566
gene id: 8128:LOC100690566
uniprot id: A0A669BA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

8128:LOC100702924
gene id: 8128:LOC100702924
uniprot id: A0A669BZQ2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:pprc1
gene id: 8128:pprc1
uniprot id: I3JSV2
names: Subcellular Location Annotation
messages: Nucleus

8128:rpl13
gene id: 8128:rpl13
uniprot id: I3JF29
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

8128:LOC100701527
gene id: 8128:LOC100701527
uniprot id: I3J385
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:dgat2
gene id: 8128:dgat2
uniprot id: I3JZG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:pam
gene id: 8128:pam
uniprot id: A0A669CS46
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 2 Cu(2+) ions per subunit.
messages: Binds one Zn(2+) ion per subunit.
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Membrane
messages: secretory vesicle membrane

8128:ppp1r1a
gene id: 8128:ppp1r1a
uniprot id: A0A669BV25
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

8128:LOC100702817
gene id: 8128:LOC100702817
uniprot id: I3JRI8
names: Similarity
messages: Belongs to the intermediate filament family.

8128:sirt2
gene id: 8128:sirt2
uniprot id: I3KII7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

8128:LOC100697564
gene id: 8128:LOC100697564
uniprot id: I3KVV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8128:mrto4
gene id: 8128:mrto4
uniprot id: I3KA58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

8128:LOC100701694
gene id: 8128:LOC100701694
uniprot id: I3KUQ3
names: Similarity
messages: Belongs to the TGF-beta family.

8128:sybu
gene id: 8128:sybu
uniprot id: I3ITX7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100691388
gene id: 8128:LOC100691388
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100700131
gene id: 8128:LOC100700131
uniprot id: I3JJE5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100705775
gene id: 8128:LOC100705775
uniprot id: A0A669EMX6
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100693249
gene id: 8128:LOC100693249
uniprot id: A0A669FA52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC109204650
gene id: 8128:LOC109204650
uniprot id: A0A669CY97
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:LOC100701534
gene id: 8128:LOC100701534
uniprot id: A0A669D6H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100709410
gene id: 8128:LOC100709410
uniprot id: I3JCS8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

8128:miga2
gene id: 8128:miga2
uniprot id: I3JK98
names: Similarity
messages: Belongs to the mitoguardin family.

8128:fam3a
gene id: 8128:fam3a
uniprot id: I3K1W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8128:ppic
gene id: 8128:ppic
uniprot id: I3K8C7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:susd6
gene id: 8128:susd6
uniprot id: I3JEG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:sfxn5
gene id: 8128:sfxn5
uniprot id: I3K2X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

8128:LOC100692622
gene id: 8128:LOC100692622
uniprot id: I3JCB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8128:tollip
gene id: 8128:tollip
uniprot id: A0A669CGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

8128:LOC100700549
gene id: 8128:LOC100700549
uniprot id: A0A669FAH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:tmcc2
gene id: 8128:tmcc2
uniprot id: I3KRV1
names: Similarity
messages: Belongs to the TEX28 family.

8128:LOC100712317
gene id: 8128:LOC100712317
uniprot id: I3KKH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100706059
gene id: 8128:LOC100706059
uniprot id: A0A669FAV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8128:slc13a4
gene id: 8128:slc13a4
uniprot id: A0A669DHG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8128:apmap
gene id: 8128:apmap
uniprot id: I3JJA2
names: Similarity
messages: Belongs to the strictosidine synthase family.

8128:tm2d3
gene id: 8128:tm2d3
uniprot id: A0A669AVI5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC102077300
gene id: 8128:LOC102077300
uniprot id: A0A669AVU7
uniprot id: A0A669BGZ3
uniprot id: A0A669D9T2
names: Subcellular Location Annotation
messages: Membrane

8128:lpar3
gene id: 8128:lpar3
uniprot id: A0A669BE22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100703194
gene id: 8128:LOC100703194
uniprot id: I3KQM9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8128:dusp1
gene id: 8128:dusp1
uniprot id: A0A669E212
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8128:cmtm3
gene id: 8128:cmtm3
uniprot id: A0A669EA84
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690324
gene id: 8128:LOC100690324
uniprot id: A0A669FBJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

8128:LOC100706477
gene id: 8128:LOC100706477
uniprot id: A0A669E418
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:tap1
gene id: 8128:tap1
uniprot id: I3JPU7
names: Subcellular Location Annotation
messages: Membrane

8128:hmgcll1
gene id: 8128:hmgcll1
uniprot id: A0A669CLH3
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

8128:stard5
gene id: 8128:stard5
uniprot id: I3KCU7
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

8128:asic2
gene id: 8128:asic2
uniprot id: A0A669DWU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100693182
gene id: 8128:LOC100693182
uniprot id: I3J1V0
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8128:akap9
gene id: 8128:akap9
uniprot id: A0A669C522
uniprot id: A0A669CVR8
names: Subcellular Location Annotation
messages: centrosome

8128:LOC100700011
gene id: 8128:LOC100700011
uniprot id: I3KQV2
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100711079
gene id: 8128:LOC100711079
uniprot id: I3JAS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

8128:LOC100706976
gene id: 8128:LOC100706976
uniprot id: A0A669DHR3
names: Similarity
messages: Belongs to the RAMP family.

8128:mpc2
gene id: 8128:mpc2
uniprot id: A0A669B158
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8128:creld2
gene id: 8128:creld2
uniprot id: A0A669DW93
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100700932
gene id: 8128:LOC100700932
uniprot id: A0A669C820
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

8128:LOC100704908
gene id: 8128:LOC100704908
uniprot id: I3K3Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

8128:kpnb1
gene id: 8128:kpnb1
uniprot id: A0A669AZK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

8128:LOC100705835
gene id: 8128:LOC100705835
uniprot id: I3KSR1
names: Subcellular Location Annotation
messages: Membrane

8128:dusp4
gene id: 8128:dusp4
uniprot id: A0A669EPA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8128:LOC100708925
gene id: 8128:LOC100708925
uniprot id: A0A669ET18
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100698412
gene id: 8128:LOC100698412
uniprot id: I3KP30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100700539
gene id: 8128:LOC100700539
uniprot id: I3K4A1
names: Similarity
messages: Belongs to the SPIN/STSY family.

8128:bbs2
gene id: 8128:bbs2
uniprot id: A0A669CDQ9
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

8128:tmem136
gene id: 8128:tmem136
uniprot id: A0A669DVK8
names: Subcellular Location Annotation
messages: Membrane

8128:btaf1
gene id: 8128:btaf1
uniprot id: I3KC32
names: Subcellular Location Annotation
messages: Nucleus

8128:armt1
gene id: 8128:armt1
uniprot id: I3K6Q9
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

8128:cluap1
gene id: 8128:cluap1
uniprot id: A0A669BIW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

8128:suox
gene id: 8128:suox
uniprot id: I3KSS0
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.
messages: Mitochondrion intermembrane space

8128:sod1
gene id: 8128:sod1
uniprot id: A0A669EY15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

8128:LOC100534441
gene id: 8128:LOC100534441
uniprot id: B7SU42
uniprot id: I3KY06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8128:LOC100693612
gene id: 8128:LOC100693612
uniprot id: I3JGK2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100700294
gene id: 8128:LOC100700294
uniprot id: I3KHF6
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8128:LOC100709687
gene id: 8128:LOC100709687
uniprot id: A0A669DG95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

8128:elp5
gene id: 8128:elp5
uniprot id: I3KRW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

8128:idh3b
gene id: 8128:idh3b
uniprot id: A0A669BN46
uniprot id: A0A669C898
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

8128:letmd1
gene id: 8128:letmd1
uniprot id: I3KIW6
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100710173
gene id: 8128:LOC100710173
uniprot id: A0A669DCC5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:LOC100699274
gene id: 8128:LOC100699274
uniprot id: A0A669AZ93
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:LOC100699393
gene id: 8128:LOC100699393
uniprot id: I3J7U4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100689752
gene id: 8128:LOC100689752
uniprot id: I3KMZ8
names: Similarity
messages: Belongs to the centrin family.

8128:LOC100712218
gene id: 8128:LOC100712218
uniprot id: I3KUS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8128:entpd4
gene id: 8128:entpd4
uniprot id: I3K115
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8128:LOC100693708
gene id: 8128:LOC100693708
uniprot id: A0A669BF09
uniprot id: I3KIM6
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8128:LOC100706802
gene id: 8128:LOC100706802
uniprot id: I3KE52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8128:nkx3-2
gene id: 8128:nkx3-2
uniprot id: A0A669CKW2
names: Subcellular Location Annotation
messages: Nucleus

8128:sult1a4
gene id: 8128:sult1a4
uniprot id: I3K017
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC100706043
gene id: 8128:LOC100706043
uniprot id: A0A669FCD5
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:pdk4
gene id: 8128:pdk4
uniprot id: A0A669AXU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8128:gsg1
gene id: 8128:gsg1
uniprot id: A0A669BW35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8128:ppp1r16b
gene id: 8128:ppp1r16b
uniprot id: A0A669E6F4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:stx18
gene id: 8128:stx18
uniprot id: I3KTK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

8128:LOC100708666
gene id: 8128:LOC100708666
uniprot id: A0A669AY15
uniprot id: A0A669BTZ2
uniprot id: A0A669BWS5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100696448
gene id: 8128:LOC100696448
uniprot id: I3J5U3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102079351
gene id: 8128:LOC102079351
uniprot id: A0A669CCQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8128:tmem267
gene id: 8128:tmem267
uniprot id: A0A669DNG8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709163
gene id: 8128:LOC100709163
uniprot id: I3KMM3
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Membrane

8128:LOC100693652
gene id: 8128:LOC100693652
uniprot id: I3KMJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8128:atp6v1e1
gene id: 8128:atp6v1e1
uniprot id: A0A669F2E2
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

8128:tmod1
gene id: 8128:tmod1
uniprot id: A0A669AWL6
uniprot id: I3KH22
names: Subcellular Location Annotation
messages: cytoskeleton

8128:tph1
gene id: 8128:tph1
uniprot id: I3JNE1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8128:LOC100696227
gene id: 8128:LOC100696227
uniprot id: I3J8K6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710426
gene id: 8128:LOC100710426
uniprot id: A0A669F5K1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC102075719
gene id: 8128:LOC102075719
uniprot id: A0A669D3R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8128:ngdn
gene id: 8128:ngdn
uniprot id: I3JMW6
names: Subcellular Location Annotation
messages: nucleolus

8128:LOC100703776
gene id: 8128:LOC100703776
uniprot id: A0A669BSX9
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8128:nsfl1c
gene id: 8128:nsfl1c
uniprot id: I3IZL4
names: Subcellular Location Annotation
messages: Golgi stack

8128:LOC102078258
gene id: 8128:LOC102078258
uniprot id: A0A669EGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8128:urad
gene id: 8128:urad
uniprot id: I3K9H9
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

8128:LOC100696172
gene id: 8128:LOC100696172
uniprot id: A0A669EKX1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100703777
gene id: 8128:LOC100703777
uniprot id: A0A669BN08
uniprot id: A0A669CN70
names: Subcellular Location Annotation
messages: Membrane

8128:LOC102079948
gene id: 8128:LOC102079948
uniprot id: A0A669CUA2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100696184
gene id: 8128:LOC100696184
uniprot id: A0A669EV99
uniprot id: I3JPQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

8128:LOC100702220
gene id: 8128:LOC100702220
uniprot id: A0A669CDJ6
names: Subcellular Location Annotation
messages: ruffle membrane

8128:churc1
gene id: 8128:churc1
uniprot id: I3JFN0
names: Similarity
messages: Belongs to the Churchill family.

8128:LOC100696716
gene id: 8128:LOC100696716
uniprot id: A0A669EFA4
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

8128:LOC100693443
gene id: 8128:LOC100693443
uniprot id: I3K3B3
names: Similarity
messages: Belongs to the AHA1 family.

8128:rbx1
gene id: 8128:rbx1
uniprot id: I3JP46
names: Similarity
messages: Belongs to the RING-box family.

8128:LOC100690950
gene id: 8128:LOC100690950
uniprot id: I3KDT8
names: Similarity
messages: Belongs to the SLA2 family.

8128:gpat3
gene id: 8128:gpat3
uniprot id: I3K3Q8
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:LOC100703720
gene id: 8128:LOC100703720
uniprot id: I3KGC9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693236
gene id: 8128:LOC100693236
uniprot id: I3JU15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

8128:ssr1
gene id: 8128:ssr1
uniprot id: A0A669BBF9
uniprot id: I3KI17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

8128:LOC100690911
gene id: 8128:LOC100690911
uniprot id: I3J3N4
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC100709014
gene id: 8128:LOC100709014
uniprot id: I3JIP7
names: Subcellular Location Annotation
messages: Nucleus

8128:fam199x
gene id: 8128:fam199x
uniprot id: A0A669C7L7
names: Similarity
messages: Belongs to the FAM199 family.

8128:LOC100708912
gene id: 8128:LOC100708912
uniprot id: I3K5H9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC109194179
gene id: 8128:LOC109194179
uniprot id: I3K3J8
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

8128:ints9
gene id: 8128:ints9
uniprot id: A0A669BBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

8128:esco2
gene id: 8128:esco2
uniprot id: I3J867
names: Subcellular Location Annotation
messages: Nucleus

8128:kcnc4
gene id: 8128:kcnc4
uniprot id: I3J2R8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100710044
gene id: 8128:LOC100710044
uniprot id: A0A669CBN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

8128:eif3b
gene id: 8128:eif3b
uniprot id: I3J5H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

8128:rexo2
gene id: 8128:rexo2
uniprot id: A0A669DDC5
names: Similarity
messages: Belongs to the oligoribonuclease family.

8128:LOC100690594
gene id: 8128:LOC100690594
uniprot id: A0A669CZ90
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

8128:exoc3
gene id: 8128:exoc3
uniprot id: A0A669ERC5
names: Similarity
messages: Belongs to the SEC6 family.

8128:LOC100703394
gene id: 8128:LOC100703394
uniprot id: I3JWY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:hexdc
gene id: 8128:hexdc
uniprot id: A0A669DAL5
uniprot id: A0A669F2R8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

8128:LOC100691200
gene id: 8128:LOC100691200
uniprot id: I3K5F4
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8128:fbxo25
gene id: 8128:fbxo25
uniprot id: I3K740
uniprot id: I3K741
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100707982
gene id: 8128:LOC100707982
uniprot id: I3JQ73
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:snx6
gene id: 8128:snx6
uniprot id: I3JYE0
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

8128:oaf
gene id: 8128:oaf
uniprot id: A0A669C377
names: Similarity
messages: Belongs to the OAF family.

8128:stam2
gene id: 8128:stam2
uniprot id: A0A669DI81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

8128:ddx59
gene id: 8128:ddx59
uniprot id: I3K3T9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

8128:LOC102080283
gene id: 8128:LOC102080283
uniprot id: A0A669DU16
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8128:dlx1
gene id: 8128:dlx1
uniprot id: I3JQ22
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102076967
gene id: 8128:LOC102076967
uniprot id: I3KG59
names: Similarity
messages: Belongs to the arrestin family.

8128:LOC102083160
gene id: 8128:LOC102083160
uniprot id: I3JJZ3
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:cckar
gene id: 8128:cckar
uniprot id: I3JS24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100701419
gene id: 8128:LOC100701419
uniprot id: I3JMP2
names: Subcellular Location Annotation
messages: Membrane

8128:cnot8
gene id: 8128:cnot8
uniprot id: A0A669B0D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8128:LOC102079550
gene id: 8128:LOC102079550
uniprot id: A0A669BA41
names: Similarity
messages: Belongs to the peptidase S1B family.

8128:LOC102079252
gene id: 8128:LOC102079252
uniprot id: I3JRE9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100705613
gene id: 8128:LOC100705613
uniprot id: I3KFF1
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:med1
gene id: 8128:med1
uniprot id: A0A669BV18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8128:arsj
gene id: 8128:arsj
uniprot id: I3JDD5
names: Similarity
messages: Belongs to the sulfatase family.

8128:LOC100704978
gene id: 8128:LOC100704978
uniprot id: I3JCE2
names: Similarity
messages: Belongs to the WD repeat coronin family.

8128:rabggta
gene id: 8128:rabggta
uniprot id: I3J432
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

8128:LOC100706132
gene id: 8128:LOC100706132
uniprot id: I3JL92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:phgdh
gene id: 8128:phgdh
uniprot id: A0A669FAZ8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8128:pomgnt1
gene id: 8128:pomgnt1
uniprot id: I3JM09
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

8128:LOC100712257
gene id: 8128:LOC100712257
uniprot id: I3J406
names: Similarity
messages: Belongs to the OSBP family.

8128:pdss2
gene id: 8128:pdss2
uniprot id: I3KTY7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8128:LOC100704814
gene id: 8128:LOC100704814
uniprot id: I3KW51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100703749
gene id: 8128:LOC100703749
uniprot id: I3KMD4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8128:psmd2
gene id: 8128:psmd2
uniprot id: I3JXE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

8128:LOC100692589
gene id: 8128:LOC100692589
uniprot id: A0A669CJM5
names: Subcellular Location Annotation
messages: Secreted

8128:map1lc3a
gene id: 8128:map1lc3a
uniprot id: A0A669E0Y3
names: Similarity
messages: Belongs to the ATG8 family.

8128:LOC100700374
gene id: 8128:LOC100700374
uniprot id: A0A669B127
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8128:fam102b
gene id: 8128:fam102b
uniprot id: A0A669C110
names: Similarity
messages: Belongs to the EEIG family.

8128:hhat
gene id: 8128:hhat
uniprot id: I3IXG3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100701165
gene id: 8128:LOC100701165
uniprot id: A0A669CMA1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100711398
gene id: 8128:LOC100711398
uniprot id: I3J7B8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

8128:LOC100706997
gene id: 8128:LOC100706997
uniprot id: A0A669CRG5
uniprot id: I3KHA9
uniprot id: I3KHB0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

8128:gmpr
gene id: 8128:gmpr
uniprot id: A0A669CQY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

8128:alg8
gene id: 8128:alg8
uniprot id: I3JKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC106098215
gene id: 8128:LOC106098215
uniprot id: A0A669DYJ4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8128:srrt
gene id: 8128:srrt
uniprot id: I3J900
names: Similarity
messages: Belongs to the ARS2 family.

8128:pop5
gene id: 8128:pop5
uniprot id: I3JYW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

8128:LOC102080373
gene id: 8128:LOC102080373
uniprot id: A0A669BWL5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:agtrap
gene id: 8128:agtrap
uniprot id: A0A669EZR1
names: Subcellular Location Annotation
messages: Membrane

8128:tmem177
gene id: 8128:tmem177
uniprot id: I3J9Q8
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

8128:bves
gene id: 8128:bves
uniprot id: A0A669EGS3
names: Similarity
messages: Belongs to the popeye family.

8128:acap1
gene id: 8128:acap1
uniprot id: A0A669F0G5
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8128:eif3h
gene id: 8128:eif3h
uniprot id: I3JJM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8128:ptpn14
gene id: 8128:ptpn14
uniprot id: A0A669B1A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

8128:LOC100691298
gene id: 8128:LOC100691298
uniprot id: I3K5C4
names: Similarity
messages: Belongs to the FAM53 family.

8128:capn9
gene id: 8128:capn9
uniprot id: A0A669C4Q8
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:LOC100698083
gene id: 8128:LOC100698083
uniprot id: A0A669B481
uniprot id: A0A669BNG1
uniprot id: A0A669E3P4
uniprot id: I3JJZ1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

8128:LOC100702988
gene id: 8128:LOC100702988
uniprot id: I3J9J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8128:LOC109195824
gene id: 8128:LOC109195824
uniprot id: A0A669CZB2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100707199
gene id: 8128:LOC100707199
uniprot id: I3K4B1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

8128:jph2
gene id: 8128:jph2
uniprot id: I3KI59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8128:LOC100699061
gene id: 8128:LOC100699061
uniprot id: I3KAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:ubap2l
gene id: 8128:ubap2l
uniprot id: A0A669BJ84
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100694569
gene id: 8128:LOC100694569
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100692710
gene id: 8128:LOC100692710
uniprot id: A0A669F5M3
names: Subcellular Location Annotation
messages: Nucleus

8128:chpf
gene id: 8128:chpf
uniprot id: A0A669AYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8128:LOC100703512
gene id: 8128:LOC100703512
uniprot id: A0A669DXG6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:ankh
gene id: 8128:ankh
uniprot id: A0A669EZG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

8128:ranbp10
gene id: 8128:ranbp10
uniprot id: A0A669DM06
names: Similarity
messages: Belongs to the RANBP9/10 family.

8128:LOC100696337
gene id: 8128:LOC100696337
uniprot id: A0A669E085
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8128:mrpl52
gene id: 8128:mrpl52
uniprot id: I3KNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

8128:LOC102075498
gene id: 8128:LOC102075498
uniprot id: A0A669CJP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100710540
gene id: 8128:LOC100710540
uniprot id: A0A669EU67
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100698259
gene id: 8128:LOC100698259
uniprot id: I3JHC7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100695190
gene id: 8128:LOC100695190
uniprot id: I3KKV7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:st14
gene id: 8128:st14
uniprot id: I3J8E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:surf6
gene id: 8128:surf6
uniprot id: I3JZC0
names: Similarity
messages: Belongs to the SURF6 family.

8128:snx10
gene id: 8128:snx10
uniprot id: A0A669DKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8128:wnt1
gene id: 8128:wnt1
uniprot id: A0A669C859
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:hbs1l
gene id: 8128:hbs1l
uniprot id: A0A669EGN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm

8128:LOC100709063
gene id: 8128:LOC100709063
uniprot id: I3KME5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690984
gene id: 8128:LOC100690984
uniprot id: I3K5Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8128:gosr1
gene id: 8128:gosr1
uniprot id: A0A669BLG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

8128:LOC100690550
gene id: 8128:LOC100690550
uniprot id: I3K0W4
names: Subcellular Location Annotation
messages: Cytoplasm

8128:kif3b
gene id: 8128:kif3b
uniprot id: I3IVI3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:eaf1
gene id: 8128:eaf1
uniprot id: I3JHZ1
names: Similarity
messages: Belongs to the EAF family.

8128:LOC100703074
gene id: 8128:LOC100703074
uniprot id: A0A669F506
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8128:smc2
gene id: 8128:smc2
uniprot id: A0A669BTB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

8128:LOC100705914
gene id: 8128:LOC100705914
uniprot id: I3KK84
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

8128:LOC100697104
gene id: 8128:LOC100697104
uniprot id: I3J7N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

8128:gdpd2
gene id: 8128:gdpd2
uniprot id: I3J3P9
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8128:mmp15
gene id: 8128:mmp15
uniprot id: I3J563
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8128:LOC100698696
gene id: 8128:LOC100698696
uniprot id: A0A669CEI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

8128:LOC100711955
gene id: 8128:LOC100711955
uniprot id: I3J4N8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100704464
gene id: 8128:LOC100704464
uniprot id: A0A482G0X0
names: Similarity
messages: Belongs to the pleurocidin family.

8128:fign
gene id: 8128:fign
uniprot id: A0A669EYT7
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:gjc2
gene id: 8128:gjc2
uniprot id: I3JSR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100701625
gene id: 8128:LOC100701625
uniprot id: A0A669BXI5
names: Similarity
messages: Belongs to the TGF-beta family.

8128:fgg
gene id: 8128:fgg
uniprot id: I3JVB3
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

8128:LOC100689998
gene id: 8128:LOC100689998
uniprot id: A0A669D991
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100705258
gene id: 8128:LOC100705258
uniprot id: I3KBI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:LOC100694047
gene id: 8128:LOC100694047
uniprot id: A0A669EXR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8128:mrps11
gene id: 8128:mrps11
uniprot id: A0A669CGG0
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

8128:opa3
gene id: 8128:opa3
uniprot id: I3J863
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

8128:tp73
gene id: 8128:tp73
uniprot id: A0A669D526
uniprot id: A0A669DDD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

8128:LOC106096880
gene id: 8128:LOC106096880
uniprot id: A0A669D350
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100694118
gene id: 8128:LOC100694118
uniprot id: A0A669F556
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100710942
gene id: 8128:LOC100710942
uniprot id: F8TJW7
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

8128:LOC100707481
gene id: 8128:LOC100707481
uniprot id: I3KJP9
uniprot id: I3KJQ0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100692341
gene id: 8128:LOC100692341
uniprot id: I3JLK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8128:LOC100710013
gene id: 8128:LOC100710013
uniprot id: I3KI29
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:evx1
gene id: 8128:evx1
uniprot id: A0A669E2P1
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100708685
gene id: 8128:LOC100708685
uniprot id: I3KZ13
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

8128:LOC109198956
gene id: 8128:LOC109198956
uniprot id: A0A669DWU0
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:LOC100691127
gene id: 8128:LOC100691127
uniprot id: A0A669CDV0
names: Similarity
messages: Belongs to the MHC class I family.

8128:LOC102076492
gene id: 8128:LOC102076492
uniprot id: I3KZU5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100700023
gene id: 8128:LOC100700023
uniprot id: I3KHF4
names: Similarity
messages: Belongs to the heme oxygenase family.

8128:LOC100698253
gene id: 8128:LOC100698253
uniprot id: A0A669DQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8128:LOC100706207
gene id: 8128:LOC100706207
uniprot id: I3IZQ6
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100709239
gene id: 8128:LOC100709239
uniprot id: I3J388
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

8128:LOC100706230
gene id: 8128:LOC100706230
uniprot id: A0A669CLN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8128:LOC100702368
gene id: 8128:LOC100702368
uniprot id: A0A669C5A7
uniprot id: A0A669D0B8
uniprot id: I3JL02
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100692316
gene id: 8128:LOC100692316
uniprot id: I3JW22
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100699029
gene id: 8128:LOC100699029
uniprot id: I3JAM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:LOC100694377
gene id: 8128:LOC100694377
uniprot id: A0A669CQ87
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8128:itgb1
gene id: 8128:itgb1
uniprot id: A0A669BIJ9
uniprot id: A0A669EIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

8128:atp1b2
gene id: 8128:atp1b2
uniprot id: I3J8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8128:vps36
gene id: 8128:vps36
uniprot id: I3JAW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

8128:LOC100701041
gene id: 8128:LOC100701041
uniprot id: A0A669CY78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8128:LOC100696367
gene id: 8128:LOC100696367
uniprot id: I3JRQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8128:prkcb
gene id: 8128:prkcb
uniprot id: A0A669CYC2
uniprot id: A0A669D1G9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

8128:thbs3
gene id: 8128:thbs3
uniprot id: A0A669B7Y3
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:nsun2
gene id: 8128:nsun2
uniprot id: I3JLN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

8128:LOC100712049
gene id: 8128:LOC100712049
uniprot id: I3KKF8
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8128:LOC100704238
gene id: 8128:LOC100704238
uniprot id: A0A669CW66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8128:LOC100702776
gene id: 8128:LOC100702776
uniprot id: I3JBC8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

8128:vasn
gene id: 8128:vasn
uniprot id: A0A669CRU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ralyl
gene id: 8128:ralyl
uniprot id: I3JGN9
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

8128:ppm1e
gene id: 8128:ppm1e
uniprot id: I3KL85
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100704190
gene id: 8128:LOC100704190
uniprot id: I3J3Z7
names: Subcellular Location Annotation
messages: Secreted

8128:LOC100701785
gene id: 8128:LOC100701785
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:LOC100700351
gene id: 8128:LOC100700351
uniprot id: I3KTB9
names: Similarity
messages: Belongs to the CAMK2N family.

8128:LOC100707394
gene id: 8128:LOC100707394
uniprot id: I3JGH5
names: Similarity
messages: Belongs to the GAB family.

8128:LOC102079941
gene id: 8128:LOC102079941
uniprot id: I3K0T7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:plcd4
gene id: 8128:plcd4
uniprot id: I3JJJ7
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

8128:relt
gene id: 8128:relt
uniprot id: I3JBW0
names: Similarity
messages: Belongs to the RELT family.

8128:rbm17
gene id: 8128:rbm17
uniprot id: I3K1B1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

8128:pdha1
gene id: 8128:pdha1
uniprot id: I3JNA4
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

8128:sf3b5
gene id: 8128:sf3b5
uniprot id: I3KY34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

8128:bloc1s3
gene id: 8128:bloc1s3
uniprot id: I3JBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S3 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).
messages: Cytoplasm

8128:xkrx
gene id: 8128:xkrx
uniprot id: I3J370
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8128:cmklr1
gene id: 8128:cmklr1
uniprot id: I3KYJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:LOC109202793
gene id: 8128:LOC109202793
uniprot id: A0A669E2Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100697952
gene id: 8128:LOC100697952
uniprot id: I3JD65
names: Similarity
messages: Belongs to the sorting nexin family.

8128:LOC100702893
gene id: 8128:LOC100702893
uniprot id: A0A669BFZ9
uniprot id: A0A669EGY3
uniprot id: I3J1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

8128:nsmce2
gene id: 8128:nsmce2
uniprot id: I3JJP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

8128:asah1
gene id: 8128:asah1
uniprot id: A0A669F2S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid ceramidase family.
messages: Lysosome

8128:LOC100690856
gene id: 8128:LOC100690856
uniprot id: I3JFB7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:nsmce4a
gene id: 8128:nsmce4a
uniprot id: I3JUF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

8128:LOC100708651
gene id: 8128:LOC100708651
uniprot id: I3JJ34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

8128:gpm6b
gene id: 8128:gpm6b
uniprot id: I3KGF7
uniprot id: I3KGF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8128:LOC100699133
gene id: 8128:LOC100699133
uniprot id: I3J7X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:cntn5
gene id: 8128:cntn5
uniprot id: A0A669EI98
uniprot id: I3JEE0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100691075
gene id: 8128:LOC100691075
uniprot id: I3J0Z1
names: Similarity
messages: Belongs to the fructosamine kinase family.

8128:kif3c
gene id: 8128:kif3c
uniprot id: I3JDP9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100693373
gene id: 8128:LOC100693373
uniprot id: A0A669CDS8
names: Similarity
messages: Belongs to the FAM219 family.

8128:agps
gene id: 8128:agps
uniprot id: A0A669DCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

8128:LOC100692860
gene id: 8128:LOC100692860
uniprot id: A0A669C494
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

8128:LOC100706405
gene id: 8128:LOC100706405
uniprot id: I3JKZ2
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8128:LOC102081783
gene id: 8128:LOC102081783
uniprot id: A0A669DY95
names: Subcellular Location Annotation
messages: Membrane

8128:LOC106097319
gene id: 8128:LOC106097319
uniprot id: A0A669F2C6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8128:LOC100692292
gene id: 8128:LOC100692292
uniprot id: I3KDZ9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:ddx31
gene id: 8128:ddx31
uniprot id: I3IWA7
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8128:mfap2
gene id: 8128:mfap2
uniprot id: I3KRR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

8128:LOC100690280
gene id: 8128:LOC100690280
uniprot id: A0A669EZ12
names: Similarity
messages: Belongs to the JAKMIP family.

8128:foxe1
gene id: 8128:foxe1
uniprot id: I3KXM6
names: Subcellular Location Annotation
messages: Nucleus

8128:atp5if1
gene id: 8128:atp5if1
uniprot id: I3KUI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

8128:LOC109203572
gene id: 8128:LOC109203572
uniprot id: A0A669DCZ7
names: Similarity
messages: Belongs to the cystatin family.

8128:agtr1
gene id: 8128:agtr1
uniprot id: A0A669DYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

8128:LOC100706360
gene id: 8128:LOC100706360
uniprot id: I3IWZ3
names: Similarity
messages: Belongs to the YY transcription factor family.

8128:slc46a1
gene id: 8128:slc46a1
uniprot id: I3JN52
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100702352
gene id: 8128:LOC100702352
uniprot id: A0A669C753
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8128:lin54
gene id: 8128:lin54
uniprot id: I3KE32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

8128:pim3
gene id: 8128:pim3
uniprot id: A0A669CR41
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8128:lg13h10orf53
gene id: 8128:lg13h10orf53
uniprot id: I3KQ80
names: Similarity
messages: Belongs to the UPF0728 family.

8128:LOC100708879
gene id: 8128:LOC100708879
uniprot id: A0A669B5U1
uniprot id: I3JMW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

8128:galnt3
gene id: 8128:galnt3
uniprot id: A0A669F423
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC109204746
gene id: 8128:LOC109204746
uniprot id: A0A669CIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:LOC100693062
gene id: 8128:LOC100693062
uniprot id: I3IY02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8128:LOC100706142
gene id: 8128:LOC100706142
uniprot id: I3KKS4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8128:evc
gene id: 8128:evc
uniprot id: I3KTJ9
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

8128:dusp27
gene id: 8128:dusp27
uniprot id: I3J6V0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8128:LOC100696948
gene id: 8128:LOC100696948
uniprot id: A0A669B6M4
uniprot id: A0A669EFK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

8128:LOC100695337
gene id: 8128:LOC100695337
uniprot id: I3KAP3
names: Subcellular Location Annotation
messages: cytoskeleton

8128:LOC100692827
gene id: 8128:LOC100692827
uniprot id: A0A669B1I4
uniprot id: I3KHV1
uniprot id: I3KHV2
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100693488
gene id: 8128:LOC100693488
uniprot id: I3JSQ9
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

8128:ptges
gene id: 8128:ptges
uniprot id: I3JZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

8128:kcnj6
gene id: 8128:kcnj6
uniprot id: I3KL73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

8128:msto1
gene id: 8128:msto1
uniprot id: I3K832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

8128:aass
gene id: 8128:aass
uniprot id: A0A669B2C6
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

8128:LOC102075668
gene id: 8128:LOC102075668
uniprot id: A0A669C7K3
uniprot id: I3J631
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8128:LOC100708189
gene id: 8128:LOC100708189
uniprot id: A0A669E7N5
names: Similarity
messages: Belongs to the PDCD4 family.

8128:LOC100712370
gene id: 8128:LOC100712370
uniprot id: A0A669BTY0
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8128:usp44
gene id: 8128:usp44
uniprot id: A0A669E8G0
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:ddx20
gene id: 8128:ddx20
uniprot id: I3K3H0
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:pgs1
gene id: 8128:pgs1
uniprot id: A0A669BYS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

8128:LOC102078110
gene id: 8128:LOC102078110
uniprot id: A0A669CQ37
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

8128:chmp7
gene id: 8128:chmp7
uniprot id: I3JYA5
names: Similarity
messages: Belongs to the SNF7 family.

8128:LOC100696313
gene id: 8128:LOC100696313
uniprot id: I3JEN7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100698653
gene id: 8128:LOC100698653
uniprot id: A0A669CEF4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100704884
gene id: 8128:LOC100704884
uniprot id: A0A669BNT0
names: Similarity
messages: Belongs to the p23/wos2 family.

8128:adamts16
gene id: 8128:adamts16
uniprot id: I3JJD5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:dll4
gene id: 8128:dll4
uniprot id: A0A669CTD2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8128:LOC100691693
gene id: 8128:LOC100691693
uniprot id: A0A669BJV1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8128:LOC100694260
gene id: 8128:LOC100694260
uniprot id: I3KLS9
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:smarcd1
gene id: 8128:smarcd1
uniprot id: A0A669CBK8
names: Similarity
messages: Belongs to the SMARCD family.

8128:LOC100694155
gene id: 8128:LOC100694155
uniprot id: I3J630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8128:LOC100711395
gene id: 8128:LOC100711395
uniprot id: I3KFV7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8128:LOC100712389
gene id: 8128:LOC100712389
uniprot id: A0A669EYR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

8128:vgll3
gene id: 8128:vgll3
uniprot id: I3J933
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

8128:LOC100702360
gene id: 8128:LOC100702360
uniprot id: I3JB06
names: Similarity
messages: Belongs to the multicopper oxidase family.

8128:LOC100696073
gene id: 8128:LOC100696073
uniprot id: I3IZM3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

8128:LOC100696595
gene id: 8128:LOC100696595
uniprot id: A0A669BH50
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:usp30
gene id: 8128:usp30
uniprot id: A0A669EQQ6
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:bmp2
gene id: 8128:bmp2
uniprot id: I3IX73
names: Similarity
messages: Belongs to the TGF-beta family.

8128:kxd1
gene id: 8128:kxd1
uniprot id: I3KBY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

8128:LOC100698262
gene id: 8128:LOC100698262
uniprot id: I3KKI7
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

8128:LOC100696007
gene id: 8128:LOC100696007
uniprot id: A0A669F3N5
uniprot id: I3JPZ0
names: Subcellular Location Annotation
messages: cytoskeleton

8128:cpn1
gene id: 8128:cpn1
uniprot id: A0A669EWQ9
names: Similarity
messages: Belongs to the peptidase M14 family.

8128:slc25a35
gene id: 8128:slc25a35
uniprot id: I3J8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:kif16b
gene id: 8128:kif16b
uniprot id: A0A669B1D7
uniprot id: I3JI77
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:LOC100697573
gene id: 8128:LOC100697573
uniprot id: I3IV05
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:lpl
gene id: 8128:lpl
uniprot id: E9K173
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

8128:LOC100709824
gene id: 8128:LOC100709824
uniprot id: A0A669BKG1
names: Similarity
messages: Belongs to the actin family.

8128:LOC100690969
gene id: 8128:LOC100690969
uniprot id: A0A669B553
uniprot id: A0A669C4P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8128:kdm6a
gene id: 8128:kdm6a
uniprot id: A0A669D6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

8128:LOC106096483
gene id: 8128:LOC106096483
uniprot id: I3IZ81
names: Similarity
messages: Belongs to the S-100 family.

8128:LOC100704249
gene id: 8128:LOC100704249
uniprot id: I3KYU9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100708898
gene id: 8128:LOC100708898
uniprot id: A0A669D483
names: Similarity
messages: Belongs to the globin family.

8128:atad2b
gene id: 8128:atad2b
uniprot id: I3IXC6
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:LOC100692353
gene id: 8128:LOC100692353
uniprot id: I3IV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

8128:cpeb2
gene id: 8128:cpeb2
uniprot id: A0A669BBT3
uniprot id: I3J4V3
names: Similarity
messages: Belongs to the RRM CPEB family.

8128:LOC100693282
gene id: 8128:LOC100693282
uniprot id: I3JZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

8128:LOC100699025
gene id: 8128:LOC100699025
uniprot id: A0A669AZN2
uniprot id: I3KBN5
names: Similarity
messages: Belongs to the DNase I family.

8128:LOC100690951
gene id: 8128:LOC100690951
uniprot id: I3KJF6
names: Subcellular Location Annotation
messages: lamellipodium
messages: sarcomere

8128:LOC100705019
gene id: 8128:LOC100705019
uniprot id: I3JV81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100701549
gene id: 8128:LOC100701549
uniprot id: I3JYU2
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:LOC102080582
gene id: 8128:LOC102080582
uniprot id: I3JG63
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

8128:nsun6
gene id: 8128:nsun6
uniprot id: I3JFG3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8128:LOC100692284
gene id: 8128:LOC100692284
uniprot id: I3K109
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

8128:lmod1
gene id: 8128:lmod1
uniprot id: A0A669D7G3
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

8128:LOC100699640
gene id: 8128:LOC100699640
uniprot id: I3JVI7
names: Similarity
messages: Belongs to the dapper family.

8128:LOC100692040
gene id: 8128:LOC100692040
uniprot id: I3IZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

8128:LOC100696814
gene id: 8128:LOC100696814
uniprot id: A0A669E7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

8128:LOC100698601
gene id: 8128:LOC100698601
uniprot id: A0A669BJF5
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC106098186
gene id: 8128:LOC106098186
uniprot id: I3JD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:dmc1
gene id: 8128:dmc1
uniprot id: Q50LF6
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

8128:LOC100694717
gene id: 8128:LOC100694717
uniprot id: I3KE80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8128:LOC100707345
gene id: 8128:LOC100707345
uniprot id: I3JA66
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:eif3i
gene id: 8128:eif3i
uniprot id: A0A669CEE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8128:smpd2
gene id: 8128:smpd2
uniprot id: I3KBL2
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

8128:LOC100696616
gene id: 8128:LOC100696616
uniprot id: I3KXI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

8128:LOC102078750
gene id: 8128:LOC102078750
uniprot id: A0A669DDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

8128:epcam
gene id: 8128:epcam
uniprot id: A0A669D2W1
uniprot id: A0A669DKU9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100710669
gene id: 8128:LOC100710669
uniprot id: I3JPK6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:immp1l
gene id: 8128:immp1l
uniprot id: A0A669C395
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

8128:lrrfip2
gene id: 8128:lrrfip2
uniprot id: A0A669B5F4
uniprot id: A0A669B5Z9
uniprot id: A0A669CW20
uniprot id: I3JVJ2
names: Similarity
messages: Belongs to the LRRFIP family.

8128:LOC100710494
gene id: 8128:LOC100710494
uniprot id: I3JXA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8128:dusp8
gene id: 8128:dusp8
uniprot id: A0A669EDR9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8128:mapk1
gene id: 8128:mapk1
uniprot id: A0A669F2G2
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8128:sptlc2
gene id: 8128:sptlc2
uniprot id: I3IXN5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8128:LOC100702547
gene id: 8128:LOC100702547
uniprot id: I3J8L3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:six1
gene id: 8128:six1
uniprot id: I3KW47
names: Subcellular Location Annotation
messages: Nucleus

8128:plcg1
gene id: 8128:plcg1
uniprot id: I3KLJ3
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

8128:LOC100694218
gene id: 8128:LOC100694218
uniprot id: A0A669EJ63
uniprot id: A0A669F0S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100695225
gene id: 8128:LOC100695225
uniprot id: I3KNX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

8128:ap1m1
gene id: 8128:ap1m1
uniprot id: I3KQJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

8128:LOC102082138
gene id: 8128:LOC102082138
uniprot id: I3J7L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8128:LOC100702798
gene id: 8128:LOC100702798
uniprot id: A0A669EBH1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100707183
gene id: 8128:LOC100707183
uniprot id: A0A669EC18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100691757
gene id: 8128:LOC100691757
uniprot id: I3KEU8
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

8128:esam
gene id: 8128:esam
uniprot id: A0A669BSA8
names: Subcellular Location Annotation
messages: Membrane

8128:marcks
gene id: 8128:marcks
uniprot id: A0A669BAX8
names: Similarity
messages: Belongs to the MARCKS family.

8128:LOC100710917
gene id: 8128:LOC100710917
uniprot id: I3JSY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8128:LOC100705047
gene id: 8128:LOC100705047
uniprot id: I3KWL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:pdss1
gene id: 8128:pdss1
uniprot id: I3JGT4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8128:adam19
gene id: 8128:adam19
uniprot id: I3KMD0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100703377
gene id: 8128:LOC100703377
uniprot id: A0A669CRV2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709804
gene id: 8128:LOC100709804
uniprot id: A0A669EQN2
names: Similarity
messages: Belongs to the S-100 family.

8128:LOC100711823
gene id: 8128:LOC100711823
uniprot id: I3JTQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8128:LOC100703537
gene id: 8128:LOC100703537
uniprot id: A0A669C4V7
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:neil3
gene id: 8128:neil3
uniprot id: I3IXZ7
names: Similarity
messages: Belongs to the FPG family.

8128:gatc
gene id: 8128:gatc
uniprot id: A0A669BU14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8128:LOC100698089
gene id: 8128:LOC100698089
uniprot id: A0A669EKV9
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100693802
gene id: 8128:LOC100693802
uniprot id: A0A669BH75
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:hexa
gene id: 8128:hexa
uniprot id: A0A669B675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

8128:usp20
gene id: 8128:usp20
uniprot id: A0A669DN48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

8128:uxs1
gene id: 8128:uxs1
uniprot id: A0A669BP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

8128:dlgap2
gene id: 8128:dlgap2
uniprot id: A0A669DTC6
names: Similarity
messages: Belongs to the SAPAP family.

8128:LOC100706129
gene id: 8128:LOC100706129
uniprot id: I3IVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

8128:def8
gene id: 8128:def8
uniprot id: A0A669CT83
uniprot id: A0A669E9D9
names: Similarity
messages: Belongs to the DEF8 family.

8128:LOC100695260
gene id: 8128:LOC100695260
uniprot id: I3JW61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100691175
gene id: 8128:LOC100691175
uniprot id: I3IYJ6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:LOC100706924
gene id: 8128:LOC100706924
uniprot id: A0A669CVD6
uniprot id: I3JBQ1
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

8128:dctn2
gene id: 8128:dctn2
uniprot id: A0A669E4P1
names: Similarity
messages: Belongs to the dynactin subunit 2 family.

8128:sgsm3
gene id: 8128:sgsm3
uniprot id: I3J148
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

8128:LOC100700388
gene id: 8128:LOC100700388
uniprot id: I3KQ18
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:LOC100710770
gene id: 8128:LOC100710770
uniprot id: I3K2P3
names: Similarity
messages: Belongs to the KHDRBS family.

8128:LOC100693567
gene id: 8128:LOC100693567
uniprot id: A0A669BCK5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100534508
gene id: 8128:LOC100534508
uniprot id: I3J321
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:anapc15
gene id: 8128:anapc15
uniprot id: I3KJ06
names: Similarity
messages: Belongs to the APC15 family.

8128:pycr3
gene id: 8128:pycr3
uniprot id: I3JY98
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8128:LOC100711633
gene id: 8128:LOC100711633
uniprot id: I3KK07
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC109194843
gene id: 8128:LOC109194843
uniprot id: A0A669DMG5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8128:LOC100701898
gene id: 8128:LOC100701898
uniprot id: A0A669B2Z3
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

8128:tsr3
gene id: 8128:tsr3
uniprot id: I3KVK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100691977
gene id: 8128:LOC100691977
uniprot id: A0A669B921
uniprot id: A0A669D5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

8128:crtc1
gene id: 8128:crtc1
uniprot id: I3K462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100691584
gene id: 8128:LOC100691584
uniprot id: I3J5D4
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100695320
gene id: 8128:LOC100695320
uniprot id: I3ITR2
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

8128:rspo2
gene id: 8128:rspo2
uniprot id: I3ITW6
names: Similarity
messages: Belongs to the R-spondin family.

8128:plpp3
gene id: 8128:plpp3
uniprot id: A0A669AZF0
uniprot id: I3J3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:cep162
gene id: 8128:cep162
uniprot id: I3KI94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

8128:LOC100692160
gene id: 8128:LOC100692160
uniprot id: A0A669CGV2
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8128:vps25
gene id: 8128:vps25
uniprot id: A0A669EDX0
names: Similarity
messages: Belongs to the VPS25 family.

8128:gnrh2
gene id: 8128:gnrh2
uniprot id: Q76FQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.

8128:fgf13
gene id: 8128:fgf13
uniprot id: A0A669B1U6
uniprot id: A0A669ES33
uniprot id: A0A669F1F2
uniprot id: I3J3G9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:btk
gene id: 8128:btk
uniprot id: I3J2L1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:atp5md
gene id: 8128:atp5md
uniprot id: A0A669C9F3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

8128:LOC100696335
gene id: 8128:LOC100696335
uniprot id: A0A669E5Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8128:bmp8a
gene id: 8128:bmp8a
uniprot id: I3JBN6
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC106097921
gene id: 8128:LOC106097921
uniprot id: I3K1G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:vsig10
gene id: 8128:vsig10
uniprot id: I3JWP4
names: Subcellular Location Annotation
messages: Membrane

8128:eif5a
gene id: 8128:eif5a
uniprot id: A0A669BNN0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

8128:mcm8
gene id: 8128:mcm8
uniprot id: I3IYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8128:LOC100693919
gene id: 8128:LOC100693919
uniprot id: I3IUU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8128:cdx4
gene id: 8128:cdx4
uniprot id: A0A669B8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

8128:cltb
gene id: 8128:cltb
uniprot id: A0A669BS30
uniprot id: A0A669C2Q8
uniprot id: A0A669CV51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

8128:LOC100692495
gene id: 8128:LOC100692495
uniprot id: I3KPC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

8128:lmod3
gene id: 8128:lmod3
uniprot id: A0A669BM64
names: Subcellular Location Annotation
messages: cytoskeleton

8128:vkorc1l1
gene id: 8128:vkorc1l1
uniprot id: I3K4N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:slc5a5
gene id: 8128:slc5a5
uniprot id: I3K417
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8128:fgf16
gene id: 8128:fgf16
uniprot id: H2E8V5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:LOC100710271
gene id: 8128:LOC100710271
uniprot id: I3KTQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8128:LOC100697998
gene id: 8128:LOC100697998
uniprot id: I3IUD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8128:LOC100702930
gene id: 8128:LOC100702930
uniprot id: A0A669EKG9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

8128:pgm2l1
gene id: 8128:pgm2l1
uniprot id: A0A669CUP7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8128:znf532
gene id: 8128:znf532
uniprot id: I3JLF0
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

8128:aldh1l2
gene id: 8128:aldh1l2
uniprot id: I3K1V3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

8128:LOC100706964
gene id: 8128:LOC100706964
uniprot id: I3JGH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8128:kdelr3
gene id: 8128:kdelr3
uniprot id: A0A669B962
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100704824
gene id: 8128:LOC100704824
uniprot id: I3KEQ2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

8128:fam207a
gene id: 8128:fam207a
uniprot id: A0A669F229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

8128:LOC100690425
gene id: 8128:LOC100690425
uniprot id: A0A669E8R0
uniprot id: I3J043
names: Similarity
messages: Belongs to the OSBP family.

8128:LOC100691947
gene id: 8128:LOC100691947
uniprot id: A0A669BI95
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8128:LOC100690141
gene id: 8128:LOC100690141
uniprot id: A0A669ELT3
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8128:LOC100704030
gene id: 8128:LOC100704030
uniprot id: A0A669EL00
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.

8128:LOC100702908
gene id: 8128:LOC100702908
uniprot id: A0A669C2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
messages: Membrane

8128:LOC100702701
gene id: 8128:LOC100702701
uniprot id: I3K1N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100691973
gene id: 8128:LOC100691973
uniprot id: I3J2F9
names: Subcellular Location Annotation
messages: extracellular space

8128:gla
gene id: 8128:gla
uniprot id: I3J2M7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

8128:LOC100693476
gene id: 8128:LOC100693476
uniprot id: A0A669B5K7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:txnrd2
gene id: 8128:txnrd2
uniprot id: I3KFL9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

8128:LOC100696877
gene id: 8128:LOC100696877
uniprot id: I3KYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100702189
gene id: 8128:LOC100702189
uniprot id: I3J6E8
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100696427
gene id: 8128:LOC100696427
uniprot id: I3KC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

8128:gdf6
gene id: 8128:gdf6
uniprot id: A0A669CPY5
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC100697652
gene id: 8128:LOC100697652
uniprot id: I3KUG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100711568
gene id: 8128:LOC100711568
uniprot id: A0A669CQS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

8128:LOC100692894
gene id: 8128:LOC100692894
uniprot id: A0A669BJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8128:timm22
gene id: 8128:timm22
uniprot id: I3K4W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100706975
gene id: 8128:LOC100706975
uniprot id: A0A669BZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8128:slc39a8
gene id: 8128:slc39a8
uniprot id: I3KU46
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100691516
gene id: 8128:LOC100691516
uniprot id: A0A669F3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8128:LOC100696572
gene id: 8128:LOC100696572
uniprot id: A0A669CYQ4
names: Subcellular Location Annotation
messages: Membrane

8128:prpf3
gene id: 8128:prpf3
uniprot id: A0A669BQI2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

8128:LOC100712494
gene id: 8128:LOC100712494
uniprot id: A0A669BUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

8128:LOC109204655
gene id: 8128:LOC109204655
uniprot id: A0A669ELM7
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100707512
gene id: 8128:LOC100707512
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:LOC100696147
gene id: 8128:LOC100696147
uniprot id: I3JHW2
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

8128:LOC100701953
gene id: 8128:LOC100701953
uniprot id: I3KEZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8128:LOC100691107
gene id: 8128:LOC100691107
uniprot id: I3JZ62
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8128:cdo1
gene id: 8128:cdo1
uniprot id: I3KAR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

8128:calcrl
gene id: 8128:calcrl
uniprot id: I3JAC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8128:LOC109195683
gene id: 8128:LOC109195683
uniprot id: A0A669BXN1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC102079339
gene id: 8128:LOC102079339
uniprot id: A0A669E777
uniprot id: I3KGK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8128:dcaf11
gene id: 8128:dcaf11
uniprot id: I3JMX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

8128:LOC100702161
gene id: 8128:LOC100702161
uniprot id: I3IXJ2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:slc29a3
gene id: 8128:slc29a3
uniprot id: I3JUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

8128:dnal4
gene id: 8128:dnal4
uniprot id: A0A669CMQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8128:LOC100700986
gene id: 8128:LOC100700986
uniprot id: A0A669EZR7
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:LOC100696783
gene id: 8128:LOC100696783
uniprot id: I3K1F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8128:LOC100712172
gene id: 8128:LOC100712172
uniprot id: I3J2A5
names: Subcellular Location Annotation
messages: extracellular space

8128:rpl35
gene id: 8128:rpl35
uniprot id: A0A669DZ54
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

8128:tpd52
gene id: 8128:tpd52
uniprot id: A0A669BD57
uniprot id: I3J348
names: Similarity
messages: Belongs to the TPD52 family.

8128:sema5a
gene id: 8128:sema5a
uniprot id: A0A669BCS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:bgn
gene id: 8128:bgn
uniprot id: I3K3A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

8128:nipsnap1
gene id: 8128:nipsnap1
uniprot id: I3JWT9
names: Similarity
messages: Belongs to the NipSnap family.

8128:orc1
gene id: 8128:orc1
uniprot id: I3JLT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

8128:LOC100694080
gene id: 8128:LOC100694080
uniprot id: I3JFI9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:dld
gene id: 8128:dld
uniprot id: I3JXE5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

8128:LOC100693964
gene id: 8128:LOC100693964
uniprot id: I3J9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

8128:mrps9
gene id: 8128:mrps9
uniprot id: I3K727
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8128:LOC100699857
gene id: 8128:LOC100699857
uniprot id: A0A669C5R8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100694851
gene id: 8128:LOC100694851
uniprot id: A0A669B1T1
uniprot id: A0A669C4D6
names: Similarity
messages: Belongs to the villin/gelsolin family.

8128:LOC100704804
gene id: 8128:LOC100704804
uniprot id: A0A669C840
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC102078972
gene id: 8128:LOC102078972
uniprot id: I3J584
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:zdhhc4
gene id: 8128:zdhhc4
uniprot id: I3KUW6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:inka2
gene id: 8128:inka2
uniprot id: A0A669CTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8128:snx19
gene id: 8128:snx19
uniprot id: I3KBS3
names: Similarity
messages: Belongs to the sorting nexin family.

8128:bmt2
gene id: 8128:bmt2
uniprot id: I3JQL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

8128:ddit4l
gene id: 8128:ddit4l
uniprot id: I3K750
names: Similarity
messages: Belongs to the DDIT4 family.

8128:lhx1
gene id: 8128:lhx1
uniprot id: I3JW83
names: Subcellular Location Annotation
messages: Nucleus

8128:cyr61
gene id: 8128:cyr61
uniprot id: I3JQK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:galns
gene id: 8128:galns
uniprot id: A0A669E870
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Homodimer.
messages: Lysosome

8128:LOC100709494
gene id: 8128:LOC100709494
uniprot id: I3KRN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

8128:clmp
gene id: 8128:clmp
uniprot id: I3JD13
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100703546
gene id: 8128:LOC100703546
uniprot id: A0A669CJJ0
uniprot id: A0A669CWH6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:tes
gene id: 8128:tes
uniprot id: A0A669BW87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

8128:LOC100693665
gene id: 8128:LOC100693665
uniprot id: A0A669D2J5
uniprot id: I3J5Y6
names: Similarity
messages: Belongs to the OSBP family.

8128:fam198a
gene id: 8128:fam198a
uniprot id: A0A669AV16
names: Similarity
messages: Belongs to the GASK family.

8128:LOC100709493
gene id: 8128:LOC100709493
uniprot id: I3JUL7
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:LOC100693926
gene id: 8128:LOC100693926
uniprot id: A0A669DKH4
names: Similarity
messages: Belongs to the COX20 family.

8128:LOC100690929
gene id: 8128:LOC100690929
uniprot id: I3KGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8128:LOC100696665
gene id: 8128:LOC100696665
uniprot id: A0A669CFJ2
uniprot id: I3J9C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8128:mknk2
gene id: 8128:mknk2
uniprot id: I3JUY9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:gtf2h3
gene id: 8128:gtf2h3
uniprot id: I3K6A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

8128:LOC100698905
gene id: 8128:LOC100698905
uniprot id: A0A669DZ45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

8128:mrpl46
gene id: 8128:mrpl46
uniprot id: A0A669FC70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

8128:twf2
gene id: 8128:twf2
uniprot id: A0A669AX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

8128:LOC100707403
gene id: 8128:LOC100707403
uniprot id: I3J7Y8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8128:mterf1
gene id: 8128:mterf1
uniprot id: I3KUX1
names: Similarity
messages: Belongs to the mTERF family.

8128:plod2
gene id: 8128:plod2
uniprot id: A0A669CKA2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

8128:nppc
gene id: 8128:nppc
uniprot id: A0A669E8F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8128:LOC100708706
gene id: 8128:LOC100708706
uniprot id: A0A669DHM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

8128:LOC100705328
gene id: 8128:LOC100705328
uniprot id: A0A669ES37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100699983
gene id: 8128:LOC100699983
uniprot id: I3KJR8
names: Similarity
messages: Belongs to the TAFA family.

8128:xrcc3
gene id: 8128:xrcc3
uniprot id: I3IUM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Cytoplasm
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
messages: Nucleus

8128:LOC100702127
gene id: 8128:LOC100702127
uniprot id: I3JVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8128:ythdf1
gene id: 8128:ythdf1
uniprot id: A0A669C2W3
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

8128:LOC100696446
gene id: 8128:LOC100696446
uniprot id: I3JUX9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

8128:LOC100691356
gene id: 8128:LOC100691356
uniprot id: A0A669B645
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

8128:LOC100696536
gene id: 8128:LOC100696536
uniprot id: I3KNI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:ptpn12
gene id: 8128:ptpn12
uniprot id: I3K0Y8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.

8128:LOC100690310
gene id: 8128:LOC100690310
uniprot id: I3JF86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8128:LOC100700345
gene id: 8128:LOC100700345
uniprot id: I3J520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

8128:adam11
gene id: 8128:adam11
uniprot id: A0A669EG79
uniprot id: I3KHD3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:rab11fip3
gene id: 8128:rab11fip3
uniprot id: I3KVP9
uniprot id: I3KVQ1
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

8128:rps12
gene id: 8128:rps12
uniprot id: O13019
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

8128:LOC109202395
gene id: 8128:LOC109202395
uniprot id: A0A669B354
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8128:b3gnt3
gene id: 8128:b3gnt3
uniprot id: I3K445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100697320
gene id: 8128:LOC100697320
uniprot id: I3J1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:LOC100708361
gene id: 8128:LOC100708361
uniprot id: I3KH21
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100699616
gene id: 8128:LOC100699616
uniprot id: I3JH21
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:lmnb2
gene id: 8128:lmnb2
uniprot id: I3JLL0
names: Similarity
messages: Belongs to the intermediate filament family.

8128:LOC100693032
gene id: 8128:LOC100693032
uniprot id: I3KF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100694585
gene id: 8128:LOC100694585
uniprot id: A0A669CC94
names: Similarity
messages: Belongs to the apolipoprotein L family.

8128:LOC100705673
gene id: 8128:LOC100705673
uniprot id: I3JLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8128:LOC100700200
gene id: 8128:LOC100700200
uniprot id: I3J7V1
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100691852
gene id: 8128:LOC100691852
uniprot id: A0A669CVQ2
names: Function
names: Similarity
messages: Belongs to the CMP-Neu5Ac hydroxylase family.
messages: Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.

8128:atp13a1
gene id: 8128:atp13a1
uniprot id: I3J0F7
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

8128:slc25a26
gene id: 8128:slc25a26
uniprot id: I3KX04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:LOC100708462
gene id: 8128:LOC100708462
uniprot id: I3KBS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell projection
messages: Cytoplasm
messages: Membrane

8128:kcnk12
gene id: 8128:kcnk12
uniprot id: I3JU49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:cmtm7
gene id: 8128:cmtm7
uniprot id: I3J0U9
names: Subcellular Location Annotation
messages: Membrane

8128:kctd3
gene id: 8128:kctd3
uniprot id: I3KKI4
names: Similarity
messages: Belongs to the KCTD3 family.

8128:LOC109201896
gene id: 8128:LOC109201896
uniprot id: A0A669CWC7
names: Similarity
messages: Belongs to the globin family.

8128:ppil4
gene id: 8128:ppil4
uniprot id: I3JZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:LOC102079959
gene id: 8128:LOC102079959
uniprot id: A0A669DN51
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8128:sgf29
gene id: 8128:sgf29
uniprot id: I3JSD9
names: Subcellular Location Annotation
messages: Nucleus

8128:snrpe
gene id: 8128:snrpe
uniprot id: A0A669EMR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

8128:LOC100708473
gene id: 8128:LOC100708473
uniprot id: I3KG53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

8128:slain1
gene id: 8128:slain1
uniprot id: A0A669F141
uniprot id: I3JHZ0
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

8128:LOC100697912
gene id: 8128:LOC100697912
uniprot id: I3KBJ5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8128:rnf114
gene id: 8128:rnf114
uniprot id: I3KLI0
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.
messages: Nucleus

8128:kcnc1
gene id: 8128:kcnc1
uniprot id: A0A669BWF1
uniprot id: A0A669DEA8
names: Subcellular Location Annotation
messages: Membrane

8128:actl6a
gene id: 8128:actl6a
uniprot id: A0A669CTP7
names: Similarity
messages: Belongs to the actin family.

8128:hacl1
gene id: 8128:hacl1
uniprot id: A0A669D2V1
names: Similarity
messages: Belongs to the TPP enzyme family.

8128:rbp4
gene id: 8128:rbp4
uniprot id: I3KHT1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:tlx3
gene id: 8128:tlx3
uniprot id: A0A669EZE1
names: Subcellular Location Annotation
messages: Nucleus

8128:ccnf
gene id: 8128:ccnf
uniprot id: I3JCF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus
messages: centriole
messages: perinuclear region

8128:nprl2
gene id: 8128:nprl2
uniprot id: I3J807
names: Similarity
messages: Belongs to the NPR2 family.

8128:LOC102077686
gene id: 8128:LOC102077686
uniprot id: A0A669DBV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:gsdf
gene id: 8128:gsdf
uniprot id: E9RGV7
names: Similarity
messages: Belongs to the TGF-beta family.

8128:uroc1
gene id: 8128:uroc1
uniprot id: I3KS62
names: Similarity
messages: Belongs to the urocanase family.

8128:crhbp
gene id: 8128:crhbp
uniprot id: I3KE96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

8128:LOC100696682
gene id: 8128:LOC100696682
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:thbs1b
gene id: 8128:thbs1b
uniprot id: C5HIF2
uniprot id: I3K260
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:coq5
gene id: 8128:coq5
uniprot id: I3JWK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

8128:LOC100705521
gene id: 8128:LOC100705521
uniprot id: I3K0X0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8128:LOC100691791
gene id: 8128:LOC100691791
uniprot id: A0A669CBW4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:lactb2
gene id: 8128:lactb2
uniprot id: I3KCD2
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

8128:foxo3
gene id: 8128:foxo3
uniprot id: I3K6H3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100711773
gene id: 8128:LOC100711773
uniprot id: I3JY55
names: Similarity
messages: Belongs to the BRINP family.

8128:dnaaf4
gene id: 8128:dnaaf4
uniprot id: I3K4E1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

8128:LOC100701229
gene id: 8128:LOC100701229
uniprot id: I3JR77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:susd2
gene id: 8128:susd2
uniprot id: A0A669CNE4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:pola2
gene id: 8128:pola2
uniprot id: I3JCK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

8128:dnpep
gene id: 8128:dnpep
uniprot id: A0A669DTT1
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

8128:LOC100699840
gene id: 8128:LOC100699840
uniprot id: A0A669CTP5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8128:mpv17l2
gene id: 8128:mpv17l2
uniprot id: I3K4G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8128:wrnip1
gene id: 8128:wrnip1
uniprot id: I3JTA9
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

8128:LOC100703596
gene id: 8128:LOC100703596
uniprot id: I3IVR0
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

8128:LOC102080585
gene id: 8128:LOC102080585
uniprot id: I3JT34
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:pde5a
gene id: 8128:pde5a
uniprot id: A0A669BK72
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:tacr2
gene id: 8128:tacr2
uniprot id: I3KK33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100706789
gene id: 8128:LOC100706789
uniprot id: A0A669DCU3
names: Similarity
messages: Belongs to the FAM20 family.

8128:LOC100694776
gene id: 8128:LOC100694776
uniprot id: I3JAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:LOC100691053
gene id: 8128:LOC100691053
uniprot id: I3IWS8
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

8128:tctex1d2
gene id: 8128:tctex1d2
uniprot id: A0A669DQT5
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8128:LOC100694732
gene id: 8128:LOC100694732
uniprot id: A0A669F009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8128:LOC102075629
gene id: 8128:LOC102075629
uniprot id: I3J9I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

8128:LOC102076024
gene id: 8128:LOC102076024
uniprot id: I3K9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8128:ivd
gene id: 8128:ivd
uniprot id: A0A669CVG8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8128:LOC100690577
gene id: 8128:LOC100690577
uniprot id: I3KPX7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100691320
gene id: 8128:LOC100691320
uniprot id: I3IWU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8128:kif1bp
gene id: 8128:kif1bp
uniprot id: I3JDF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

8128:ptger3
gene id: 8128:ptger3
uniprot id: A0A669EF83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:gdf9
gene id: 8128:gdf9
uniprot id: I3K542
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC100708930
gene id: 8128:LOC100708930
uniprot id: A0A669CTE5
names: Similarity
messages: Belongs to the centaurin gamma-like family.

8128:polb
gene id: 8128:polb
uniprot id: A0A669EXG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

8128:LOC100691608
gene id: 8128:LOC100691608
uniprot id: I3KRW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:rnf13
gene id: 8128:rnf13
uniprot id: A0A669D2L7
names: Subcellular Location Annotation
messages: Membrane

8128:uba5
gene id: 8128:uba5
uniprot id: A0A669CLC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Golgi apparatus

8128:ptgfr
gene id: 8128:ptgfr
uniprot id: I3J144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:pcsk7
gene id: 8128:pcsk7
uniprot id: A0A669EB91
names: Similarity
messages: Belongs to the peptidase S8 family.

8128:sh3rf1
gene id: 8128:sh3rf1
uniprot id: I3J4S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

8128:LOC100710620
gene id: 8128:LOC100710620
uniprot id: I3JIE1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

8128:cdc42ep4
gene id: 8128:cdc42ep4
uniprot id: I3KY92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8128:LOC100696266
gene id: 8128:LOC100696266
uniprot id: A0A669BXC5
names: Subcellular Location Annotation
messages: Nucleus

8128:magoh
gene id: 8128:magoh
uniprot id: I3KSV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

8128:LOC100697790
gene id: 8128:LOC100697790
uniprot id: I3KRI5
uniprot id: I3KRI6
names: Similarity
messages: Belongs to the CEP170 family.

8128:nfe2
gene id: 8128:nfe2
uniprot id: A0A669B8Z4
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8128:arap1
gene id: 8128:arap1
uniprot id: I3KIW8
uniprot id: I3KIW9
uniprot id: I3KIX0
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC106096557
gene id: 8128:LOC106096557
uniprot id: A0A669CH32
names: Subcellular Location Annotation
messages: Nucleus

8128:kdm2a
gene id: 8128:kdm2a
uniprot id: A0A669D5G1
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8128:tnmd
gene id: 8128:tnmd
uniprot id: A0A669DST4
names: Similarity
messages: Belongs to the chondromodulin-1 family.

8128:itga11
gene id: 8128:itga11
uniprot id: I3JE40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100709286
gene id: 8128:LOC100709286
uniprot id: I3JIR0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:kcnk3
gene id: 8128:kcnk3
uniprot id: I3JF97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:glud1
gene id: 8128:glud1
uniprot id: I3JJ04
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

8128:atp23
gene id: 8128:atp23
uniprot id: I3JUG0
names: Similarity
messages: Belongs to the peptidase M76 family.

8128:LOC100705087
gene id: 8128:LOC100705087
uniprot id: A0A669E7E8
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC102080671
gene id: 8128:LOC102080671
uniprot id: A0A669DAX2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100696620
gene id: 8128:LOC100696620
uniprot id: I3JMR7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC100703095
gene id: 8128:LOC100703095
uniprot id: I3J4C8
names: Similarity
messages: Belongs to the exportin family.

8128:LOC100690586
gene id: 8128:LOC100690586
uniprot id: A0A669B5H8
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

8128:atp1b3
gene id: 8128:atp1b3
uniprot id: A0A669BGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8128:LOC100710567
gene id: 8128:LOC100710567
uniprot id: A0A669B1F9
names: Similarity
messages: Belongs to the heme oxygenase family.

8128:LOC100708876
gene id: 8128:LOC100708876
uniprot id: I3JTG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

8128:cbfb
gene id: 8128:cbfb
uniprot id: A0A669BEM5
uniprot id: A0A669CDX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

8128:gns
gene id: 8128:gns
uniprot id: I3KN68
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:nfe2l1
gene id: 8128:nfe2l1
uniprot id: A0A669D3P3
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8128:LOC100712278
gene id: 8128:LOC100712278
uniprot id: A0A669DJX7
uniprot id: I3J2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC100694454
gene id: 8128:LOC100694454
uniprot id: I3J7I7
names: Similarity
messages: Belongs to the HEBP family.

8128:LOC100693646
gene id: 8128:LOC100693646
uniprot id: I3K815
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100700589
gene id: 8128:LOC100700589
uniprot id: I3KKD8
names: Similarity
messages: Belongs to the GCF family.

8128:LOC100705437
gene id: 8128:LOC100705437
uniprot id: A0A669E6W7
uniprot id: I3JAR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8128:LOC100693924
gene id: 8128:LOC100693924
uniprot id: I3JV48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:slc48a1
gene id: 8128:slc48a1
uniprot id: A0A669EZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

8128:LOC100706784
gene id: 8128:LOC100706784
uniprot id: I3K1D7
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:LOC100692151
gene id: 8128:LOC100692151
uniprot id: I3JU06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8128:LOC100699208
gene id: 8128:LOC100699208
uniprot id: I3JQE2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100699346
gene id: 8128:LOC100699346
uniprot id: I3J4L6
names: Subcellular Location Annotation
messages: Nucleus

8128:oxr1
gene id: 8128:oxr1
uniprot id: A0A669BK17
uniprot id: A0A669EPX0
names: Similarity
messages: Belongs to the OXR1 family.

8128:LOC100691587
gene id: 8128:LOC100691587
uniprot id: I3JJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100693140
gene id: 8128:LOC100693140
uniprot id: A0A669DIU7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:blcap
gene id: 8128:blcap
uniprot id: A0A669CMF9
names: Similarity
messages: Belongs to the BLCAP family.

8128:cldn15
gene id: 8128:cldn15
uniprot id: I3JS66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:sap130
gene id: 8128:sap130
uniprot id: I3KT60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

8128:tmem59
gene id: 8128:tmem59
uniprot id: I3KQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100711058
gene id: 8128:LOC100711058
uniprot id: A0A669E0P1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:txnl4a
gene id: 8128:txnl4a
uniprot id: A0A669BPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

8128:tubgcp2
gene id: 8128:tubgcp2
uniprot id: A0A669AZ23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

8128:LOC100702891
gene id: 8128:LOC100702891
uniprot id: I3J6J6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8128:hdac2
gene id: 8128:hdac2
uniprot id: I3JZJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

8128:tut4
gene id: 8128:tut4
uniprot id: I3KTP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

8128:ercc5
gene id: 8128:ercc5
uniprot id: I3J4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

8128:LOC100691451
gene id: 8128:LOC100691451
uniprot id: A0A669F0G7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8128:phax
gene id: 8128:phax
uniprot id: I3KZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

8128:gnb1
gene id: 8128:gnb1
uniprot id: A0A669ESQ8
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8128:LOC100695282
gene id: 8128:LOC100695282
uniprot id: I3KS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8128:LOC100711322
gene id: 8128:LOC100711322
uniprot id: A0A669B9D7
names: Similarity
messages: Belongs to the myozenin family.

8128:ptprk
gene id: 8128:ptprk
uniprot id: A0A669CL27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

8128:barx1
gene id: 8128:barx1
uniprot id: A0A669BIE9
names: Subcellular Location Annotation
messages: Nucleus

8128:sbf1
gene id: 8128:sbf1
uniprot id: A0A669AX59
uniprot id: A0A669BUN0
uniprot id: A0A669EKZ1
uniprot id: I3K1M8
uniprot id: I3K1M9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8128:tada3
gene id: 8128:tada3
uniprot id: I3KWW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

8128:cldn20
gene id: 8128:cldn20
uniprot id: A0A669DU30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100700261
gene id: 8128:LOC100700261
uniprot id: I3K486
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100690812
gene id: 8128:LOC100690812
uniprot id: I3J0Y1
uniprot id: I3J0Y2
names: Similarity
messages: Belongs to the epsin family.

8128:LOC100708442
gene id: 8128:LOC100708442
uniprot id: I3JYF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8128:LOC100693293
gene id: 8128:LOC100693293
uniprot id: A0A669AZ64
names: Subcellular Location Annotation
messages: Membrane

8128:fsip1
gene id: 8128:fsip1
uniprot id: I3K256
names: Similarity
messages: Belongs to the FSIP1 family.

8128:pllp
gene id: 8128:pllp
uniprot id: I3JVH6
names: Subcellular Location Annotation
messages: Membrane

8128:ppcs
gene id: 8128:ppcs
uniprot id: I3J7V0
names: Similarity
messages: Belongs to the PPC synthetase family.

8128:LOC100705420
gene id: 8128:LOC100705420
uniprot id: I3K7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8128:magi2
gene id: 8128:magi2
uniprot id: A0A669BFL7
uniprot id: A0A669FAI8
uniprot id: I3IU21
names: Subcellular Location Annotation
messages: Membrane

8128:folh1b
gene id: 8128:folh1b
uniprot id: I3JC87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

8128:mb21d2
gene id: 8128:mb21d2
uniprot id: I3IY24
names: Similarity
messages: Belongs to the mab-21 family.

8128:nol10
gene id: 8128:nol10
uniprot id: I3KU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

8128:LOC100710273
gene id: 8128:LOC100710273
uniprot id: I3KDP1
names: Subcellular Location Annotation
messages: Membrane

8128:steap3
gene id: 8128:steap3
uniprot id: A0A669BY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8128:LOC100690838
gene id: 8128:LOC100690838
uniprot id: A0A669AZW8
uniprot id: A0A669B3L9
uniprot id: A0A669BK33
uniprot id: A0A669CIV5
uniprot id: A0A669D9K1
uniprot id: A0A669ETN5
uniprot id: I3KNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

8128:LOC100700435
gene id: 8128:LOC100700435
uniprot id: I3KI68
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8128:LOC100712078
gene id: 8128:LOC100712078
uniprot id: I3K493
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC109201890
gene id: 8128:LOC109201890
uniprot id: A0A669DGW0
names: Similarity
messages: Belongs to the Bcl-2 family.

8128:ovca2
gene id: 8128:ovca2
uniprot id: I3JDV9
names: Similarity
messages: Belongs to the LovG family.

8128:tctn1
gene id: 8128:tctn1
uniprot id: I3K0G0
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

8128:LOC100691753
gene id: 8128:LOC100691753
uniprot id: I3JNC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

8128:LOC100705541
gene id: 8128:LOC100705541
uniprot id: I3IWR3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100699906
gene id: 8128:LOC100699906
uniprot id: I3KSA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8128:LOC100693900
gene id: 8128:LOC100693900
uniprot id: A0A669D6C0
uniprot id: A0A669F264
names: Subcellular Location Annotation
messages: Cytoplasm

8128:cnksr3
gene id: 8128:cnksr3
uniprot id: I3JMY7
names: Similarity
messages: Belongs to the CNKSR family.

8128:LOC100711919
gene id: 8128:LOC100711919
uniprot id: A0A669EC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:chst12
gene id: 8128:chst12
uniprot id: I3J5H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:ptpn21
gene id: 8128:ptpn21
uniprot id: A0A669DLL6
uniprot id: I3IYU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

8128:ppp2r5b
gene id: 8128:ppp2r5b
uniprot id: A0A669ECH1
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8128:fam171a2
gene id: 8128:fam171a2
uniprot id: I3KNZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8128:LOC106098620
gene id: 8128:LOC106098620
uniprot id: A0A669BP33
names: Similarity
messages: Belongs to the cornifelin family.

8128:mmgt1
gene id: 8128:mmgt1
uniprot id: A0A669DEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

8128:slc4a11
gene id: 8128:slc4a11
uniprot id: A0A669B761
uniprot id: A0A669BUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

8128:ufd1
gene id: 8128:ufd1
uniprot id: I3KAF4
names: Similarity
messages: Belongs to the UFD1 family.

8128:LOC100698057
gene id: 8128:LOC100698057
uniprot id: I3KCD6
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

8128:LOC100697993
gene id: 8128:LOC100697993
uniprot id: I3J9F5
names: Similarity
messages: Belongs to the ependymin family.

8128:atp6v1a
gene id: 8128:atp6v1a
uniprot id: A0A669EGJ4
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

8128:bet1l
gene id: 8128:bet1l
uniprot id: A0A669EHF2
names: Subcellular Location Annotation
messages: Membrane

8128:daxx
gene id: 8128:daxx
uniprot id: I3JNW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

8128:dnm3
gene id: 8128:dnm3
uniprot id: A0A669D5U0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8128:vopp1
gene id: 8128:vopp1
uniprot id: I3KD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8128:fam83h
gene id: 8128:fam83h
uniprot id: I3J2N7
names: Similarity
messages: Belongs to the FAM83 family.

8128:LOC100709580
gene id: 8128:LOC100709580
uniprot id: I3KYC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:tmem218
gene id: 8128:tmem218
uniprot id: A0A669CVJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

8128:KEH09 p10
gene id: 8128:KEH09_p10
uniprot id: D2KP27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100698988
gene id: 8128:LOC100698988
uniprot id: A0A669EJB8
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100704433
gene id: 8128:LOC100704433
uniprot id: I3J8P7
names: Subcellular Location Annotation
messages: Nucleus

8128:ptk2b
gene id: 8128:ptk2b
uniprot id: I3KDQ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

8128:LOC100703516
gene id: 8128:LOC100703516
uniprot id: A0A669EC11
names: Similarity
messages: Belongs to the globin family.

8128:LOC100703170
gene id: 8128:LOC100703170
uniprot id: I3KCY0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8128:nr4a2
gene id: 8128:nr4a2
uniprot id: A0A669E453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8128:neu3a
gene id: 8128:neu3a
uniprot id: I3JCG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8128:LOC100699947
gene id: 8128:LOC100699947
uniprot id: I3KQA9
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

8128:LOC100699861
gene id: 8128:LOC100699861
uniprot id: I3KTM4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC106098593
gene id: 8128:LOC106098593
uniprot id: A0A669C3G9
names: Function
names: Similarity
names: Subunit
messages: Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
messages: Belongs to the fucolectin family.
messages: Homotrimer.

8128:LOC100705181
gene id: 8128:LOC100705181
uniprot id: I3KKL0
uniprot id: I3KKL1
names: Similarity
messages: Belongs to the lipin family.

8128:rogdi
gene id: 8128:rogdi
uniprot id: A0A669DMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Presynapse
messages: Vesicle
messages: synaptic vesicle

8128:pick1
gene id: 8128:pick1
uniprot id: A0A669DEM6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
messages: cytoskeleton
messages: perinuclear region
messages: synaptosome

8128:ptpra
gene id: 8128:ptpra
uniprot id: I3KX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC100712075
gene id: 8128:LOC100712075
uniprot id: A0A669CKV8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

8128:ap5m1
gene id: 8128:ap5m1
uniprot id: I3KWA2
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

8128:LOC100707558
gene id: 8128:LOC100707558
uniprot id: I3JFH5
names: Similarity
messages: Belongs to the FXYD family.

8128:zfpm2
gene id: 8128:zfpm2
uniprot id: I3IUA5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100690465
gene id: 8128:LOC100690465
uniprot id: I3JC37
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690703
gene id: 8128:LOC100690703
uniprot id: I3IYX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:elac2
gene id: 8128:elac2
uniprot id: A0A669BVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Z family.
messages: mitochondrion nucleoid

8128:LOC100704147
gene id: 8128:LOC100704147
uniprot id: A0A669D0U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100697878
gene id: 8128:LOC100697878
uniprot id: I3KNM0
names: Similarity
messages: Belongs to the Luc7 family.

8128:LOC100705583
gene id: 8128:LOC100705583
uniprot id: I3K7C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8128:LOC109204964
gene id: 8128:LOC109204964
uniprot id: A0A669BSA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC106098523
gene id: 8128:LOC106098523
uniprot id: I3KVL0
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:ndp
gene id: 8128:ndp
uniprot id: A0A669DVU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100701790
gene id: 8128:LOC100701790
uniprot id: A0A669DTF5
names: Subcellular Location Annotation
messages: Nucleus

8128:tmem256
gene id: 8128:tmem256
uniprot id: I3KQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

8128:LOC100712390
gene id: 8128:LOC100712390
uniprot id: A0A669B963
uniprot id: A0A669E3X3
names: Subcellular Location Annotation
messages: Membrane

8128:adam8
gene id: 8128:adam8
uniprot id: I3JT75
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100692461
gene id: 8128:LOC100692461
uniprot id: I3KXC9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100700019
gene id: 8128:LOC100700019
uniprot id: I3JB54
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8128:LOC100696049
gene id: 8128:LOC100696049
uniprot id: I3JWH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:eloc
gene id: 8128:eloc
uniprot id: A0A669CWR5
names: Similarity
messages: Belongs to the SKP1 family.

8128:LOC100703897
gene id: 8128:LOC100703897
uniprot id: A0A669AZC9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:LOC100693228
gene id: 8128:LOC100693228
uniprot id: I3K298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

8128:LOC100710166
gene id: 8128:LOC100710166
uniprot id: I3JDA0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:ribc1
gene id: 8128:ribc1
uniprot id: I3K216
names: Similarity
messages: Belongs to the RIB43A family.

8128:LOC100694731
gene id: 8128:LOC100694731
uniprot id: A0A669CI39
names: Subcellular Location Annotation
messages: Membrane

8128:mrpl14
gene id: 8128:mrpl14
uniprot id: A0A669CE03
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

8128:LOC100707262
gene id: 8128:LOC100707262
uniprot id: A0A669EKJ8
uniprot id: A0A669ELT9
uniprot id: I3KFT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:abcg8
gene id: 8128:abcg8
uniprot id: I3IX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8128:LOC100694095
gene id: 8128:LOC100694095
uniprot id: A0A669EFS4
names: Caution
names: Similarity
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100695807
gene id: 8128:LOC100695807
uniprot id: A0A669CLK0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:prdx5
gene id: 8128:prdx5
uniprot id: I3J024
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

8128:syn2
gene id: 8128:syn2
uniprot id: A0A669BWJ1
names: Similarity
messages: Belongs to the synapsin family.

8128:LOC100710281
gene id: 8128:LOC100710281
uniprot id: I3J016
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8128:stip1
gene id: 8128:stip1
uniprot id: A0A669BKD9
names: Subcellular Location Annotation
messages: Cytoplasm

8128:pold3
gene id: 8128:pold3
uniprot id: I3KCU2
names: Subcellular Location Annotation
messages: Nucleus

8128:grin3b
gene id: 8128:grin3b
uniprot id: I3JA48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:LOC100704187
gene id: 8128:LOC100704187
uniprot id: A0A669C9Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8128:map3k13
gene id: 8128:map3k13
uniprot id: I3JRC8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8128:best3
gene id: 8128:best3
uniprot id: I3KNP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

8128:chac1
gene id: 8128:chac1
uniprot id: A0A669B1P0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

8128:metap1
gene id: 8128:metap1
uniprot id: I3KTT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

8128:LOC100701060
gene id: 8128:LOC100701060
uniprot id: I3IV93
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

8128:cep19
gene id: 8128:cep19
uniprot id: I3J3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

8128:LOC102079319
gene id: 8128:LOC102079319
uniprot id: A0A669BFB5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:mrpl51
gene id: 8128:mrpl51
uniprot id: A0A669AV83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.
messages: Mitochondrion

8128:LOC100704722
gene id: 8128:LOC100704722
uniprot id: I3JIL9
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100705055
gene id: 8128:LOC100705055
uniprot id: I3KZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

8128:bloc1s5
gene id: 8128:bloc1s5
uniprot id: I3KB14
names: Similarity
messages: Belongs to the BLOC1S5 family.

8128:LOC100707937
gene id: 8128:LOC100707937
uniprot id: A0A669B0M6
names: Similarity
messages: Belongs to the CNKSR family.

8128:LOC100694673
gene id: 8128:LOC100694673
uniprot id: A0A669B490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

8128:LOC100697561
gene id: 8128:LOC100697561
uniprot id: A0A669CPL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

8128:tlx1
gene id: 8128:tlx1
uniprot id: I3K621
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100705944
gene id: 8128:LOC100705944
uniprot id: I3KR15
names: Subcellular Location Annotation
messages: Nucleus

8128:laptm4a
gene id: 8128:laptm4a
uniprot id: I3JFR1
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

8128:ptcd2
gene id: 8128:ptcd2
uniprot id: I3JZ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

8128:LOC100694458
gene id: 8128:LOC100694458
uniprot id: A0A669DNV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

8128:LOC102077264
gene id: 8128:LOC102077264
uniprot id: I3KG63
names: Similarity
messages: Belongs to the arrestin family.

8128:LOC100694605
gene id: 8128:LOC100694605
uniprot id: I3KNZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

8128:LOC100690403
gene id: 8128:LOC100690403
uniprot id: I3J4R9
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

8128:LOC100703160
gene id: 8128:LOC100703160
uniprot id: I3J1Y2
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100700532
gene id: 8128:LOC100700532
uniprot id: I3KZ99
names: Subcellular Location Annotation
messages: Membrane

8128:cops4
gene id: 8128:cops4
uniprot id: I3KE36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

8128:LOC100701289
gene id: 8128:LOC100701289
uniprot id: A0A669DZB9
uniprot id: I3KP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8128:pygl
gene id: 8128:pygl
uniprot id: A0A669ERP4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

8128:hcn4
gene id: 8128:hcn4
uniprot id: A0A669DTP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8128:LOC100710678
gene id: 8128:LOC100710678
uniprot id: A0A669EEU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

8128:LOC100711711
gene id: 8128:LOC100711711
uniprot id: I3KU41
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC100696294
gene id: 8128:LOC100696294
uniprot id: A0A669DZZ0
uniprot id: I3JK32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8128:LOC102078098
gene id: 8128:LOC102078098
uniprot id: A0A669AXD1
uniprot id: A0A669DWR7
names: Subcellular Location Annotation
messages: Membrane

8128:lclat1
gene id: 8128:lclat1
uniprot id: I3IYM7
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8128:vps29
gene id: 8128:vps29
uniprot id: I3K3D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

8128:raf1
gene id: 8128:raf1
uniprot id: I3KKK9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

8128:pitx1
gene id: 8128:pitx1
uniprot id: A0A669EN61
uniprot id: A0A669EV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8128:tvp23b
gene id: 8128:tvp23b
uniprot id: I3KNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

8128:LOC100701617
gene id: 8128:LOC100701617
uniprot id: A0A669EJI1
names: Similarity
messages: Belongs to the EEIG family.

8128:stx19
gene id: 8128:stx19
uniprot id: I3J9A8
names: Similarity
messages: Belongs to the syntaxin family.

8128:LOC100699202
gene id: 8128:LOC100699202
uniprot id: I3KCL4
names: Subcellular Location Annotation
messages: extracellular space

8128:phlda2
gene id: 8128:phlda2
uniprot id: I3KX98
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100711567
gene id: 8128:LOC100711567
uniprot id: A0A669BFY6
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

8128:sema3b
gene id: 8128:sema3b
uniprot id: I3J052
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100702900
gene id: 8128:LOC100702900
uniprot id: I3JNU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:LOC100697678
gene id: 8128:LOC100697678
uniprot id: A0A669BS50
uniprot id: I3J1U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

8128:tfec
gene id: 8128:tfec
uniprot id: A0A669BJL6
uniprot id: A0A669CLN7
uniprot id: A0A669DLY2
uniprot id: I3KJ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8128:nab1
gene id: 8128:nab1
uniprot id: I3K2N3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

8128:LOC112841684
gene id: 8128:LOC112841684
uniprot id: A0A669EAU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

8128:LOC100705237
gene id: 8128:LOC100705237
uniprot id: A0A669DWN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

8128:LOC100702954
gene id: 8128:LOC100702954
uniprot id: I3KVY5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100709459
gene id: 8128:LOC100709459
uniprot id: I3KYF9
names: Similarity
messages: Belongs to the IER family.

8128:LOC100700462
gene id: 8128:LOC100700462
uniprot id: A0A669EQ53
names: Similarity
messages: Belongs to the GADD45 family.

8128:LOC106097165
gene id: 8128:LOC106097165
uniprot id: I3JIL7
names: Similarity
messages: Belongs to the HARBI1 family.

8128:LOC100694009
gene id: 8128:LOC100694009
uniprot id: I3KC54
names: Subcellular Location Annotation
messages: Nucleus

8128:stam
gene id: 8128:stam
uniprot id: I3JRR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

8128:LOC100705449
gene id: 8128:LOC100705449
uniprot id: I3KTH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

8128:LOC100700978
gene id: 8128:LOC100700978
uniprot id: A0A669CYA3
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:sgpl1
gene id: 8128:sgpl1
uniprot id: A0A669BDM4
uniprot id: I3JVT8
names: Similarity
messages: Belongs to the group II decarboxylase family.

8128:LOC100702522
gene id: 8128:LOC100702522
uniprot id: A0A669DST0
names: Similarity
messages: Belongs to the SUI1 family.

8128:LOC100702827
gene id: 8128:LOC100702827
uniprot id: I3JLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:ddit4
gene id: 8128:ddit4
uniprot id: A0A669DL06
names: Similarity
messages: Belongs to the DDIT4 family.

8128:gldc
gene id: 8128:gldc
uniprot id: A0A669F0I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

8128:tmc7
gene id: 8128:tmc7
uniprot id: I3KRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8128:LOC100695482
gene id: 8128:LOC100695482
uniprot id: A0A669DC57
names: Similarity
messages: Belongs to the actin family.

8128:nr0b1b
gene id: 8128:nr0b1b
uniprot id: Q1A7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8128:LOC100699141
gene id: 8128:LOC100699141
uniprot id: A0A669CQP1
uniprot id: I3IZQ7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8128:LOC100692049
gene id: 8128:LOC100692049
uniprot id: I3JG67
names: Subcellular Location Annotation
messages: Secreted

8128:lrfn5
gene id: 8128:lrfn5
uniprot id: A0A669B5A9
names: Subcellular Location Annotation
messages: Membrane

8128:galt
gene id: 8128:galt
uniprot id: A0A669B7I3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

8128:lck
gene id: 8128:lck
uniprot id: I3JN72
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:LOC100711837
gene id: 8128:LOC100711837
uniprot id: I3J4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

8128:LOC100703610
gene id: 8128:LOC100703610
uniprot id: A0A669BYX2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:snrnp200
gene id: 8128:snrnp200
uniprot id: I3JX75
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

8128:LOC100706678
gene id: 8128:LOC100706678
uniprot id: I3J6A6
names: Subcellular Location Annotation
messages: Nucleus

8128:osbpl9
gene id: 8128:osbpl9
uniprot id: A0A669BCS2
uniprot id: I3J0T7
names: Similarity
messages: Belongs to the OSBP family.

8128:ptpa
gene id: 8128:ptpa
uniprot id: I3K429
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:LOC100693568
gene id: 8128:LOC100693568
uniprot id: I3KID9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

8128:ric8b
gene id: 8128:ric8b
uniprot id: I3KBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

8128:LOC102076140
gene id: 8128:LOC102076140
uniprot id: A0A669C1R3
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

8128:dcn
gene id: 8128:dcn
uniprot id: Q9DE03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

8128:LOC100706970
gene id: 8128:LOC100706970
uniprot id: I3J3F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100696392
gene id: 8128:LOC100696392
uniprot id: A0A669CVX3
uniprot id: A0A669CZA3
uniprot id: A0A669F2F7
uniprot id: I3KB89
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC102079602
gene id: 8128:LOC102079602
uniprot id: I3KR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

8128:scfd1
gene id: 8128:scfd1
uniprot id: I3J0D3
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8128:p3h2
gene id: 8128:p3h2
uniprot id: I3IZV6
names: Similarity
messages: Belongs to the leprecan family.

8128:LOC102080234
gene id: 8128:LOC102080234
uniprot id: A0A669ED27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

8128:tmem106c
gene id: 8128:tmem106c
uniprot id: I3JRF7
names: Similarity
messages: Belongs to the TMEM106 family.

8128:paqr5
gene id: 8128:paqr5
uniprot id: I3K686
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8128:ube3d
gene id: 8128:ube3d
uniprot id: I3ITZ6
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

8128:LOC100699048
gene id: 8128:LOC100699048
uniprot id: A0A669F766
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

8128:LOC100704616
gene id: 8128:LOC100704616
uniprot id: A0A669E593
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8128:qars
gene id: 8128:qars
uniprot id: A0A669EGU5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8128:LOC102076382
gene id: 8128:LOC102076382
uniprot id: A0A669DHI8
names: Subcellular Location Annotation
messages: Membrane

8128:sirt5
gene id: 8128:sirt5
uniprot id: I3JGQ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-94 and Arg-97) that bind to malonylated and succinylated substrates and define the specificity.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

8128:tenm3
gene id: 8128:tenm3
uniprot id: A0A669BMJ8
uniprot id: A0A669BWT4
uniprot id: A0A669C1P2
uniprot id: A0A669C3H6
uniprot id: A0A669C4M1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:pitx2
gene id: 8128:pitx2
uniprot id: A0A669BKW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8128:LOC100690370
gene id: 8128:LOC100690370
uniprot id: I3J8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8128:LOC102076161
gene id: 8128:LOC102076161
uniprot id: A0A669DB47
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8128:aida
gene id: 8128:aida
uniprot id: I3JF58
names: Similarity
messages: Belongs to the AIDA family.

8128:LOC100695616
gene id: 8128:LOC100695616
uniprot id: I3KR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8128:luc7l
gene id: 8128:luc7l
uniprot id: A0A669BJD2
names: Similarity
messages: Belongs to the Luc7 family.

8128:LOC100700957
gene id: 8128:LOC100700957
uniprot id: I3JZK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:gpr180
gene id: 8128:gpr180
uniprot id: I3KDR3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699606
gene id: 8128:LOC100699606
uniprot id: I3K830
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8128:LOC100701062
gene id: 8128:LOC100701062
uniprot id: I3KVW2
names: Similarity
messages: Belongs to the HARBI1 family.

8128:slc17a6
gene id: 8128:slc17a6
uniprot id: I3JNI1
names: Subcellular Location Annotation
messages: Membrane

8128:pdia3
gene id: 8128:pdia3
uniprot id: A0A669EDL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8128:pln
gene id: 8128:pln
uniprot id: A0A669CP11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

8128:LOC100701200
gene id: 8128:LOC100701200
uniprot id: I3JCS0
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8128:eaf2
gene id: 8128:eaf2
uniprot id: A0A669C6R4
names: Similarity
messages: Belongs to the EAF family.

8128:emx2
gene id: 8128:emx2
uniprot id: I3JVV9
names: Subcellular Location Annotation
messages: Nucleus

8128:adrb1
gene id: 8128:adrb1
uniprot id: I3KXX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:tbx5
gene id: 8128:tbx5
uniprot id: A0A669BXN2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8128:sned1
gene id: 8128:sned1
uniprot id: I3KT47
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100707194
gene id: 8128:LOC100707194
uniprot id: A0A669BMF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:gys2
gene id: 8128:gys2
uniprot id: A0A669DB87
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

8128:LOC100690391
gene id: 8128:LOC100690391
uniprot id: A0A669C073
uniprot id: A0A669CLL9
uniprot id: I3JH44
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100703562
gene id: 8128:LOC100703562
uniprot id: I3KTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:gale
gene id: 8128:gale
uniprot id: A0A669EJ18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

8128:LOC100694608
gene id: 8128:LOC100694608
uniprot id: I3KQI6
names: Similarity
messages: Belongs to the TGF-beta family.

8128:LOC100691514
gene id: 8128:LOC100691514
uniprot id: I3JJ46
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100707272
gene id: 8128:LOC100707272
uniprot id: I3JJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8128:LOC100703448
gene id: 8128:LOC100703448
uniprot id: A0A669EV55
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709873
gene id: 8128:LOC100709873
uniprot id: I3J8W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8128:gem
gene id: 8128:gem
uniprot id: I3JFJ9
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

8128:slc41a2
gene id: 8128:slc41a2
uniprot id: I3K1U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8128:fam57a
gene id: 8128:fam57a
uniprot id: A0A669DQI3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709587
gene id: 8128:LOC100709587
uniprot id: I3KSN7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:pcyox1
gene id: 8128:pcyox1
uniprot id: I3J6N4
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

8128:nbl1
gene id: 8128:nbl1
uniprot id: A0A669C3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

8128:prpf18
gene id: 8128:prpf18
uniprot id: A0A669EIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

8128:LOC100700551
gene id: 8128:LOC100700551
uniprot id: I3JLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:ube2r2
gene id: 8128:ube2r2
uniprot id: I3KX40
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:KEH09 p12
gene id: 8128:KEH09_p12
uniprot id: D2KP25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100690728
gene id: 8128:LOC100690728
uniprot id: A0A669AVF5
uniprot id: A0A669BNV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

8128:LOC100705499
gene id: 8128:LOC100705499
uniprot id: I3JQE8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8128:maneal
gene id: 8128:maneal
uniprot id: A0A669DWE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:corin
gene id: 8128:corin
uniprot id: I3JDB7
uniprot id: I3JDB8
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:slc1a5
gene id: 8128:slc1a5
uniprot id: I3JFC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8128:nop16
gene id: 8128:nop16
uniprot id: A0A669DWR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

8128:LOC100708943
gene id: 8128:LOC100708943
uniprot id: A0A669E1M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8128:ap3b1
gene id: 8128:ap3b1
uniprot id: I3KEB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

8128:LOC100707214
gene id: 8128:LOC100707214
uniprot id: I3KRC8
names: Similarity
messages: Belongs to the beta-catenin family.

8128:LOC100704951
gene id: 8128:LOC100704951
uniprot id: I3J9Z4
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:gpatch11
gene id: 8128:gpatch11
uniprot id: I3JUY4
names: Similarity
messages: Belongs to the GPATCH11 family.

8128:LOC100690200
gene id: 8128:LOC100690200
uniprot id: I3K5R4
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8128:scmh1
gene id: 8128:scmh1
uniprot id: A0A669B7D5
uniprot id: A0A669DL35
uniprot id: I3KGY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

8128:hoxb8
gene id: 8128:hoxb8
uniprot id: A0A669E785
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100710946
gene id: 8128:LOC100710946
uniprot id: A0A669DKK5
names: Similarity
messages: Belongs to the folate receptor family.

8128:xdh
gene id: 8128:xdh
uniprot id: I3JR46
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

8128:LOC100709940
gene id: 8128:LOC100709940
uniprot id: A0A669B439
names: Similarity
messages: Belongs to the pellino family.

8128:trap1
gene id: 8128:trap1
uniprot id: A0A669CR91
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8128:sema6d
gene id: 8128:sema6d
uniprot id: A0A669DJ73
uniprot id: A0A669DZW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100711838
gene id: 8128:LOC100711838
uniprot id: A0A669DT70
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8128:LOC100709328
gene id: 8128:LOC100709328
uniprot id: A0A669BTW3
names: Similarity
messages: Belongs to the stathmin family.

8128:LOC100702682
gene id: 8128:LOC100702682
uniprot id: I3J2Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8128:exosc9
gene id: 8128:exosc9
uniprot id: I3J5Z1
names: Subcellular Location Annotation
messages: Cytoplasm

8128:abl1
gene id: 8128:abl1
uniprot id: A0A669EGR6
uniprot id: I3K9B9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8128:kcnk10
gene id: 8128:kcnk10
uniprot id: I3IYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:LOC100710552
gene id: 8128:LOC100710552
uniprot id: I3JGN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8128:myh11
gene id: 8128:myh11
uniprot id: A0A669CGZ8
uniprot id: A0A669F0N3
uniprot id: I3KRL2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100699674
gene id: 8128:LOC100699674
uniprot id: A0A669CFJ4
uniprot id: A0A669CIS0
uniprot id: A0A669CTT8
uniprot id: A0A669EUY5
uniprot id: I3JW26
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:htr2a
gene id: 8128:htr2a
uniprot id: I3KGY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: axon
messages: caveola
messages: dendrite

8128:LOC100705826
gene id: 8128:LOC100705826
uniprot id: I3KZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:LOC100693416
gene id: 8128:LOC100693416
uniprot id: A0A669BKI3
names: Subcellular Location Annotation
messages: Membrane

8128:ccnh
gene id: 8128:ccnh
uniprot id: I3KG28
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

8128:ccni
gene id: 8128:ccni
uniprot id: I3K4C0
names: Function
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

8128:cacfd1
gene id: 8128:cacfd1
uniprot id: A0A669CZW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

8128:LOC100534499
gene id: 8128:LOC100534499
uniprot id: A0A669CQU7
uniprot id: I3KVP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

8128:fgf10
gene id: 8128:fgf10
uniprot id: A0A669BY34
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:LOC100710826
gene id: 8128:LOC100710826
uniprot id: I3J278
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100701839
gene id: 8128:LOC100701839
uniprot id: I3J6R3
names: Similarity
messages: Belongs to the copine family.

8128:LOC100692351
gene id: 8128:LOC100692351
uniprot id: A0A669F712
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8128:LOC100702630
gene id: 8128:LOC100702630
uniprot id: A0A669AV07
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

8128:banp
gene id: 8128:banp
uniprot id: I3KBN7
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

8128:gins3
gene id: 8128:gins3
uniprot id: I3JXP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

8128:LOC100707506
gene id: 8128:LOC100707506
uniprot id: I3KKD2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8128:LOC102082779
gene id: 8128:LOC102082779
uniprot id: A0A669CZU0
names: Subcellular Location Annotation
messages: Membrane

8128:slc25a13
gene id: 8128:slc25a13
uniprot id: A0A669DN11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:gtpbp3
gene id: 8128:gtpbp3
uniprot id: I3JV23
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

8128:wdr48
gene id: 8128:wdr48
uniprot id: A0A669EIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Late endosome

8128:LOC100699612
gene id: 8128:LOC100699612
uniprot id: A0A669ET39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

8128:LOC100697825
gene id: 8128:LOC100697825
uniprot id: I3J545
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8128:LOC100694895
gene id: 8128:LOC100694895
uniprot id: I3KWJ3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:capn15
gene id: 8128:capn15
uniprot id: I3KVT0
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:alx1
gene id: 8128:alx1
uniprot id: I3J7J7
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102078760
gene id: 8128:LOC102078760
uniprot id: A0A669BEU5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:atrn
gene id: 8128:atrn
uniprot id: I3K2Z8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100692766
gene id: 8128:LOC100692766
uniprot id: A0A669EJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8128:LOC100695024
gene id: 8128:LOC100695024
uniprot id: A0A669CGK0
names: Similarity
messages: Belongs to the cystatin family.

8128:LOC100705883
gene id: 8128:LOC100705883
uniprot id: A0A669DHX0
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC102083041
gene id: 8128:LOC102083041
uniprot id: I3KQ05
names: Similarity
messages: Belongs to the cornifelin family.

8128:LOC102082809
gene id: 8128:LOC102082809
uniprot id: A0A669AZU9
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8128:LOC100694059
gene id: 8128:LOC100694059
uniprot id: A0A669DNE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

8128:LOC100712456
gene id: 8128:LOC100712456
uniprot id: A0A669BTE8
uniprot id: I3J8B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sodium-independent sulfate anion transporter. Can transport other anions including bicarbonate, thiosulfate and oxalate.

8128:LOC100697375
gene id: 8128:LOC100697375
uniprot id: I3J7N4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100692377
gene id: 8128:LOC100692377
uniprot id: I3J4C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:LOC100712236
gene id: 8128:LOC100712236
uniprot id: I3KLT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

8128:LOC100690091
gene id: 8128:LOC100690091
uniprot id: I3J196
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:nmb
gene id: 8128:nmb
uniprot id: I3J2T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

8128:LOC100700960
gene id: 8128:LOC100700960
uniprot id: I3J4R3
names: Subcellular Location Annotation
messages: Nucleus

8128:tmem183a
gene id: 8128:tmem183a
uniprot id: I3KT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

8128:LOC100696463
gene id: 8128:LOC100696463
uniprot id: A0A669ESS7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8128:LOC100702412
gene id: 8128:LOC100702412
uniprot id: I3JT46
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8128:dmrta1
gene id: 8128:dmrta1
uniprot id: Q9DGN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

8128:LOC100703474
gene id: 8128:LOC100703474
uniprot id: A0A669CL55
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100694966
gene id: 8128:LOC100694966
uniprot id: I3JAG6
names: Subcellular Location Annotation
messages: extracellular space

8128:luc7l3
gene id: 8128:luc7l3
uniprot id: I3J191
names: Similarity
messages: Belongs to the Luc7 family.

8128:LOC100692195
gene id: 8128:LOC100692195
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:st18
gene id: 8128:st18
uniprot id: I3JSX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

8128:chrnb1
gene id: 8128:chrnb1
uniprot id: I3KQ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:LOC100698730
gene id: 8128:LOC100698730
uniprot id: A0A669E8G1
names: Similarity
messages: Belongs to the sulfatase family.

8128:tbca
gene id: 8128:tbca
uniprot id: I3KEB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

8128:LOC100702221
gene id: 8128:LOC100702221
uniprot id: I3K9J9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100703109
gene id: 8128:LOC100703109
uniprot id: I3KDC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC102081934
gene id: 8128:LOC102081934
uniprot id: A0A669BY68
names: Similarity
messages: Belongs to the FAM83 family.

8128:mtmr4
gene id: 8128:mtmr4
uniprot id: A0A669EE29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

8128:LOC102078515
gene id: 8128:LOC102078515
uniprot id: I3K281
names: Similarity
messages: Belongs to the NLRP family.

8128:wisp2
gene id: 8128:wisp2
uniprot id: I3KI41
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:bbs5
gene id: 8128:bbs5
uniprot id: I3JQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

8128:pxmp4
gene id: 8128:pxmp4
uniprot id: A0A669ERQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

8128:LOC102080023
gene id: 8128:LOC102080023
uniprot id: A0A669EWH4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:ddah2
gene id: 8128:ddah2
uniprot id: A0A669CNT4
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

8128:LOC100699653
gene id: 8128:LOC100699653
uniprot id: A0A669BKL6
names: Subcellular Location Annotation
messages: Membrane

8128:clcn7
gene id: 8128:clcn7
uniprot id: I3KF32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

8128:LOC100534483
gene id: 8128:LOC100534483
uniprot id: C9EIT1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8128:gpd1
gene id: 8128:gpd1
uniprot id: A0A669DZV3
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

8128:LOC100701007
gene id: 8128:LOC100701007
uniprot id: A0A669EJG7
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8128:slc50a1
gene id: 8128:slc50a1
uniprot id: I3JGG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Golgi apparatus membrane
messages: Membrane

8128:yipf4
gene id: 8128:yipf4
uniprot id: A0A669C4D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:gria1
gene id: 8128:gria1
uniprot id: A0A669CG07
uniprot id: I3KM55
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:rps11
gene id: 8128:rps11
uniprot id: A0A669EN20
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8128:porcn
gene id: 8128:porcn
uniprot id: A0A669BAE0
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100694437
gene id: 8128:LOC100694437
uniprot id: A0A669F2A1
names: Similarity
messages: Belongs to the NifU family.

8128:LOC100696580
gene id: 8128:LOC100696580
uniprot id: I3JJD1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:cpm
gene id: 8128:cpm
uniprot id: I3JUI8
names: Similarity
messages: Belongs to the peptidase M14 family.

8128:LOC100703333
gene id: 8128:LOC100703333
uniprot id: A0A669EYG6
names: Subcellular Location Annotation
messages: Nucleus

8128:fam189b
gene id: 8128:fam189b
uniprot id: I3JGK4
names: Similarity
messages: Belongs to the ENTREP family.

8128:LOC100706333
gene id: 8128:LOC100706333
uniprot id: A0A669DJ54
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100697904
gene id: 8128:LOC100697904
uniprot id: C6G3Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

8128:grid2
gene id: 8128:grid2
uniprot id: A0A669CT55
uniprot id: A0A669DN97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:mfsd1
gene id: 8128:mfsd1
uniprot id: A0A669AWS6
uniprot id: A0A669DSF4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704231
gene id: 8128:LOC100704231
uniprot id: A0A669AZ32
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8128:LOC100700247
gene id: 8128:LOC100700247
uniprot id: A0A669BEX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8128:mfsd4a
gene id: 8128:mfsd4a
uniprot id: I3KJN6
names: Subcellular Location Annotation
messages: Membrane

8128:panx3
gene id: 8128:panx3
uniprot id: I3KFG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8128:cmc2
gene id: 8128:cmc2
uniprot id: A0A669B9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

8128:eya4
gene id: 8128:eya4
uniprot id: A0A669EI72
uniprot id: A0A669EUR1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

8128:LOC100706212
gene id: 8128:LOC100706212
uniprot id: I3J4I0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:opa1
gene id: 8128:opa1
uniprot id: A0A669C3B3
uniprot id: A0A669CUR0
uniprot id: I3J341
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

8128:ss18l1
gene id: 8128:ss18l1
uniprot id: I3KKF4
names: Similarity
messages: Belongs to the SS18 family.

8128:ovol1
gene id: 8128:ovol1
uniprot id: I3ITV6
names: Subcellular Location Annotation
messages: Nucleus

8128:adamts13
gene id: 8128:adamts13
uniprot id: I3JXZ9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:LOC100698466
gene id: 8128:LOC100698466
uniprot id: A0A669BCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

8128:rbm15
gene id: 8128:rbm15
uniprot id: I3J2T0
names: Similarity
messages: Belongs to the RRM Spen family.

8128:hoxc11
gene id: 8128:hoxc11
uniprot id: I3K2R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:nubpl
gene id: 8128:nubpl
uniprot id: I3J036
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

8128:mcm5
gene id: 8128:mcm5
uniprot id: I3JNC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

8128:LOC100534440
gene id: 8128:LOC100534440
uniprot id: B7SU43
uniprot id: I3KY33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8128:dmrt2
gene id: 8128:dmrt2
uniprot id: Q6YHU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8128:me1
gene id: 8128:me1
uniprot id: A0A669BAC9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

8128:LOC100693725
gene id: 8128:LOC100693725
uniprot id: I3KRP1
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8128:hoxc6
gene id: 8128:hoxc6
uniprot id: I3K2S2
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC102078091
gene id: 8128:LOC102078091
uniprot id: I3K774
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100699090
gene id: 8128:LOC100699090
uniprot id: A0A669CMJ4
uniprot id: I3JFU5
names: Subcellular Location Annotation
messages: Nucleus

8128:coro2a
gene id: 8128:coro2a
uniprot id: I3KLM7
names: Similarity
messages: Belongs to the WD repeat coronin family.

8128:LOC100701313
gene id: 8128:LOC100701313
uniprot id: I3IVT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8128:LOC100694685
gene id: 8128:LOC100694685
uniprot id: A0A669CGX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

8128:LOC100708787
gene id: 8128:LOC100708787
uniprot id: A0A669BVP0
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

8128:LOC100704022
gene id: 8128:LOC100704022
uniprot id: A0A669BG79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8128:lhx2
gene id: 8128:lhx2
uniprot id: A0A669BLA9
names: Subcellular Location Annotation
messages: Nucleus

8128:wdfy1
gene id: 8128:wdfy1
uniprot id: I3KBF6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8128:hprt1
gene id: 8128:hprt1
uniprot id: A0A669C6A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

8128:esr2
gene id: 8128:esr2
uniprot id: A0A669EL49
uniprot id: Q1KPU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8128:psme4
gene id: 8128:psme4
uniprot id: A0A669BP70
uniprot id: A0A669EJQ3
names: Similarity
messages: Belongs to the BLM10 family.

8128:LOC100702201
gene id: 8128:LOC100702201
uniprot id: A0A669BV07
uniprot id: A0A669C7H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:LOC100690997
gene id: 8128:LOC100690997
uniprot id: I3JLG6
names: Subcellular Location Annotation
messages: Nucleus

8128:gmds
gene id: 8128:gmds
uniprot id: A0A669CEY9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

8128:LOC100711588
gene id: 8128:LOC100711588
uniprot id: A0A669F711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8128:slc7a9
gene id: 8128:slc7a9
uniprot id: I3J2E8
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100690111
gene id: 8128:LOC100690111
uniprot id: I3K357
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

8128:rplp1
gene id: 8128:rplp1
uniprot id: I3J3T8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

8128:LOC102078781
gene id: 8128:LOC102078781
uniprot id: A0A669EX61
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100705747
gene id: 8128:LOC100705747
uniprot id: A0A669BFH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:anxa4
gene id: 8128:anxa4
uniprot id: I3J673
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:LOC102080070
gene id: 8128:LOC102080070
uniprot id: A0A669BFL4
names: Similarity
messages: Belongs to the dapper family.

8128:dusp5
gene id: 8128:dusp5
uniprot id: I3KHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8128:LOC100699976
gene id: 8128:LOC100699976
uniprot id: A0A669CDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:olfml2a
gene id: 8128:olfml2a
uniprot id: I3KWH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cldn5
gene id: 8128:cldn5
uniprot id: I3KX91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100693419
gene id: 8128:LOC100693419
uniprot id: I3KYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC102083061
gene id: 8128:LOC102083061
uniprot id: I3J6R7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8128:LOC100696505
gene id: 8128:LOC100696505
uniprot id: A0A669BES1
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100705156
gene id: 8128:LOC100705156
uniprot id: A0A669D320
names: Similarity
messages: Belongs to the SNF7 family.

8128:LOC109203811
gene id: 8128:LOC109203811
uniprot id: A0A669DS91
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707393
gene id: 8128:LOC100707393
uniprot id: A0A669BQT0
names: Similarity
messages: Belongs to the DeSI family.

8128:LOC100698515
gene id: 8128:LOC100698515
uniprot id: I3K945
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8128:wtap
gene id: 8128:wtap
uniprot id: I3K6C7
names: Similarity
messages: Belongs to the fl(2)d family.

8128:LOC100690250
gene id: 8128:LOC100690250
uniprot id: I3KJ34
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:cdc37
gene id: 8128:cdc37
uniprot id: A0A669DZ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

8128:LOC100705387
gene id: 8128:LOC100705387
uniprot id: A0A669CL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

8128:LOC100694981
gene id: 8128:LOC100694981
uniprot id: I3JIB6
names: Similarity
messages: Belongs to the NLRP family.

8128:LOC100706367
gene id: 8128:LOC100706367
uniprot id: A0A669F7B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8128:scn3b
gene id: 8128:scn3b
uniprot id: I3JFX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

8128:LOC100693479
gene id: 8128:LOC100693479
uniprot id: I3KYU0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:arvcf
gene id: 8128:arvcf
uniprot id: A0A669BRY3
uniprot id: A0A669CLM4
uniprot id: A0A669E5B1
uniprot id: A0A669EH60
names: Similarity
messages: Belongs to the beta-catenin family.

8128:smo
gene id: 8128:smo
uniprot id: I3K0M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium

8128:avpr1a
gene id: 8128:avpr1a
uniprot id: A0A669DUG4
uniprot id: I3JQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8128:LOC102080962
gene id: 8128:LOC102080962
uniprot id: I3JBD4
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8128:LOC100693723
gene id: 8128:LOC100693723
uniprot id: I3JWE7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8128:ttc9
gene id: 8128:ttc9
uniprot id: A0A669B091
names: Similarity
messages: Belongs to the TTC9 family.

8128:pgk1
gene id: 8128:pgk1
uniprot id: I3KL67
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

8128:LOC100693395
gene id: 8128:LOC100693395
uniprot id: I3J082
names: Subcellular Location Annotation
messages: Nucleus

8128:stoml2
gene id: 8128:stoml2
uniprot id: I3K5R5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8128:LOC100711345
gene id: 8128:LOC100711345
uniprot id: A0A669DBK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

8128:slc25a14
gene id: 8128:slc25a14
uniprot id: A0A669E5X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8128:wisp3
gene id: 8128:wisp3
uniprot id: I3JZK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:cav1
gene id: 8128:cav1
uniprot id: A0A669EXM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8128:LOC100708563
gene id: 8128:LOC100708563
uniprot id: A0A669EG52
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

8128:spdef
gene id: 8128:spdef
uniprot id: I3KBS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8128:derl2
gene id: 8128:derl2
uniprot id: I3K0D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:gna12
gene id: 8128:gna12
uniprot id: I3J5G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

8128:LOC100694595
gene id: 8128:LOC100694595
uniprot id: A0A669ETY9
uniprot id: I3JXX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8128:hoxc9
gene id: 8128:hoxc9
uniprot id: I3K2S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:sbno1
gene id: 8128:sbno1
uniprot id: I3KDW6
names: Similarity
messages: Belongs to the SBNO family.

8128:smarcd2
gene id: 8128:smarcd2
uniprot id: I3KHZ3
names: Similarity
messages: Belongs to the SMARCD family.

8128:LOC100707679
gene id: 8128:LOC100707679
uniprot id: I3KE57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8128:LOC100692191
gene id: 8128:LOC100692191
uniprot id: I3JEB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8128:bcl9l
gene id: 8128:bcl9l
uniprot id: I3JEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

8128:LOC100697530
gene id: 8128:LOC100697530
uniprot id: I3JYN4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cdk20
gene id: 8128:cdk20
uniprot id: I3KB59
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

8128:znrd1
gene id: 8128:znrd1
uniprot id: A0A669CLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

8128:asah2
gene id: 8128:asah2
uniprot id: I3KSG0
names: Similarity
messages: Belongs to the neutral ceramidase family.

8128:LOC100697389
gene id: 8128:LOC100697389
uniprot id: I3KJ73
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

8128:LOC100694918
gene id: 8128:LOC100694918
uniprot id: A0A669C425
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100690214
gene id: 8128:LOC100690214
uniprot id: I3KLJ7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:LOC100698523
gene id: 8128:LOC100698523
uniprot id: A0A669B3I3
uniprot id: A0A669D4V3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

8128:gja10
gene id: 8128:gja10
uniprot id: I3IZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:LOC100702014
gene id: 8128:LOC100702014
uniprot id: I3J8G4
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

8128:bmpr2
gene id: 8128:bmpr2
uniprot id: A0A669C656
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

8128:LOC100709519
gene id: 8128:LOC100709519
uniprot id: I3J8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8128:LOC100699062
gene id: 8128:LOC100699062
uniprot id: I3KE10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8128:LOC100691633
gene id: 8128:LOC100691633
uniprot id: I3KN35
names: Similarity
messages: Belongs to the SUA5 family.

8128:abcg1
gene id: 8128:abcg1
uniprot id: I3KKT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8128:pi4k2a
gene id: 8128:pi4k2a
uniprot id: I3KME4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

8128:LOC100699310
gene id: 8128:LOC100699310
uniprot id: A0A669BH84
uniprot id: I3K6R3
names: Subcellular Location Annotation
messages: Membrane

8128:hcrt
gene id: 8128:hcrt
uniprot id: C7T453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

8128:csrnp3
gene id: 8128:csrnp3
uniprot id: A0A669BD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8128:LOC100693017
gene id: 8128:LOC100693017
uniprot id: A0A669BY52
names: Similarity
messages: Belongs to the TGF-beta family.

8128:pmm1
gene id: 8128:pmm1
uniprot id: A0A669CWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

8128:LOC112841648
gene id: 8128:LOC112841648
uniprot id: A0A669BMK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8128:LOC100707405
gene id: 8128:LOC100707405
uniprot id: A0A669D9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like Alba family.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: nucleolus

8128:LOC100707465
gene id: 8128:LOC100707465
uniprot id: I3J8M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8128:LOC100689757
gene id: 8128:LOC100689757
uniprot id: A0A024FSQ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8128:LOC102077690
gene id: 8128:LOC102077690
uniprot id: A0A669B9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:b3gat3
gene id: 8128:b3gat3
uniprot id: A0A669C5V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC102080384
gene id: 8128:LOC102080384
uniprot id: A0A669C8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8128:tmem175
gene id: 8128:tmem175
uniprot id: A0A669C0Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

8128:tpi
gene id: 8128:tpi
uniprot id: A0A669AZJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8128:fermt2
gene id: 8128:fermt2
uniprot id: A0A669AZW4
uniprot id: A0A669F6Y3
names: Similarity
messages: Belongs to the kindlin family.

8128:sncb
gene id: 8128:sncb
uniprot id: I3KMH5
names: Similarity
messages: Belongs to the synuclein family.

8128:LOC100695750
gene id: 8128:LOC100695750
uniprot id: A0A669BE29
uniprot id: A0A669D884
names: Similarity
messages: Belongs to the beta-catenin family.

8128:mettl6
gene id: 8128:mettl6
uniprot id: A0A669B029
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

8128:cdk5rap1
gene id: 8128:cdk5rap1
uniprot id: I3KWM5
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

8128:nono
gene id: 8128:nono
uniprot id: I3KXF6
names: Subcellular Location Annotation
messages: Nucleus speckle

8128:LOC100696738
gene id: 8128:LOC100696738
uniprot id: A0A669B5I4
names: Similarity
messages: Belongs to the DDIT4 family.

8128:LOC100712084
gene id: 8128:LOC100712084
uniprot id: I3KRR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

8128:rbm22
gene id: 8128:rbm22
uniprot id: I3K5L6
names: Similarity
messages: Belongs to the SLT11 family.

8128:spty2d1
gene id: 8128:spty2d1
uniprot id: I3KAY2
names: Similarity
messages: Belongs to the SPT2 family.

8128:kcnh5
gene id: 8128:kcnh5
uniprot id: A0A669CGA4
names: Subcellular Location Annotation
messages: Membrane

8128:tor2a
gene id: 8128:tor2a
uniprot id: I3K8P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

8128:LOC100704529
gene id: 8128:LOC100704529
uniprot id: A0A669DD39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

8128:ogt
gene id: 8128:ogt
uniprot id: I3KN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

8128:fbln5
gene id: 8128:fbln5
uniprot id: I3KU95
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:agtpbp1
gene id: 8128:agtpbp1
uniprot id: I3KCM2
uniprot id: I3KCM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

8128:LOC100708190
gene id: 8128:LOC100708190
uniprot id: I3J4L9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.

8128:mindy4
gene id: 8128:mindy4
uniprot id: I3IZY2
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

8128:LOC100698647
gene id: 8128:LOC100698647
uniprot id: I3KVJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:cndp2
gene id: 8128:cndp2
uniprot id: Q3LFW5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

8128:LOC100701740
gene id: 8128:LOC100701740
uniprot id: I3J8F9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:boc
gene id: 8128:boc
uniprot id: I3K9C3
names: Subcellular Location Annotation
messages: Membrane

8128:abcd3
gene id: 8128:abcd3
uniprot id: I3JTF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

8128:LOC100693399
gene id: 8128:LOC100693399
uniprot id: A0A669BLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8128:ppm1k
gene id: 8128:ppm1k
uniprot id: I3KLK7
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100704040
gene id: 8128:LOC100704040
uniprot id: A0A669ERS7
names: Similarity
messages: Belongs to the globin family.

8128:scamp1
gene id: 8128:scamp1
uniprot id: I3KED7
uniprot id: I3KED8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8128:LOC102080805
gene id: 8128:LOC102080805
uniprot id: A0A669CFI9
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

8128:LOC100706731
gene id: 8128:LOC100706731
uniprot id: A0A669ERF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8128:tmeff2
gene id: 8128:tmeff2
uniprot id: I3JA61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100710581
gene id: 8128:LOC100710581
uniprot id: A0A669F8U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8128:puf60
gene id: 8128:puf60
uniprot id: I3JG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

8128:cspg4
gene id: 8128:cspg4
uniprot id: A0A669AVZ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100690473
gene id: 8128:LOC100690473
uniprot id: A0A481NV19
uniprot id: A0A669E5E1
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

8128:LOC100693121
gene id: 8128:LOC100693121
uniprot id: I3JW79
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8128:cc2d1b
gene id: 8128:cc2d1b
uniprot id: I3KQ15
names: Similarity
messages: Belongs to the CC2D1 family.

8128:LOC100707894
gene id: 8128:LOC100707894
uniprot id: A0A669F1D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

8128:LOC109198951
gene id: 8128:LOC109198951
uniprot id: A0A669BH49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8128:LOC100708708
gene id: 8128:LOC100708708
uniprot id: A0A669DW39
names: Similarity
messages: Belongs to the BZW family.

8128:zdhhc1
gene id: 8128:zdhhc1
uniprot id: A0A669EAP0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:mks1
gene id: 8128:mks1
uniprot id: I3KLC4
names: Subcellular Location Annotation
messages: cilium basal body

8128:LOC100699837
gene id: 8128:LOC100699837
uniprot id: I3JWB9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100702338
gene id: 8128:LOC100702338
uniprot id: I3KCB3
names: Similarity
messages: Belongs to the PP2C family.

8128:pkn1
gene id: 8128:pkn1
uniprot id: A0A669DXV1
uniprot id: A0A669FA14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

8128:LOC100704461
gene id: 8128:LOC100704461
uniprot id: I3KDI9
names: Similarity
messages: Belongs to the IUNH family.

8128:vat1l
gene id: 8128:vat1l
uniprot id: A0A669BW59
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8128:sgcb
gene id: 8128:sgcb
uniprot id: I3J4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Cross-link to form 2 major subcomplexes: one consisting of SGCB, SGCD and SGCG and the other consisting of SGCB and SGCD. The association between SGCB and SGCG is particularly strong while SGCA is loosely associated with the other sarcoglycans.
messages: cytoskeleton
messages: sarcolemma

8128:LOC100693469
gene id: 8128:LOC100693469
uniprot id: I3KK62
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC100703653
gene id: 8128:LOC100703653
uniprot id: I3JHD9
names: Subcellular Location Annotation
messages: Membrane

8128:capza2
gene id: 8128:capza2
uniprot id: A0A669C8N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8128:LOC100703879
gene id: 8128:LOC100703879
uniprot id: A0A669CIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8128:LOC100700668
gene id: 8128:LOC100700668
uniprot id: I3J728
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8128:plpp2
gene id: 8128:plpp2
uniprot id: I3IXV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8128:LOC100695940
gene id: 8128:LOC100695940
uniprot id: A0A669EYD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8128:LOC100704324
gene id: 8128:LOC100704324
uniprot id: I3IXN2
names: Similarity
messages: Belongs to the isthmin family.

8128:rps4x
gene id: 8128:rps4x
uniprot id: A0A669E0E4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

8128:dph5
gene id: 8128:dph5
uniprot id: I3JLQ4
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

8128:chst3
gene id: 8128:chst3
uniprot id: I3KGJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:psmc1
gene id: 8128:psmc1
uniprot id: I3IXY1
names: Similarity
messages: Belongs to the AAA ATPase family.

8128:LOC100710764
gene id: 8128:LOC100710764
uniprot id: I3J4W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8128:LOC109194221
gene id: 8128:LOC109194221
uniprot id: A0A669EHW4
names: Function
names: Similarity
names: Subunit
messages: Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.
messages: Belongs to the fucolectin family.
messages: Homotrimer.

8128:LOC100690520
gene id: 8128:LOC100690520
uniprot id: I3JFX6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8128:nol6
gene id: 8128:nol6
uniprot id: I3KG46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
messages: nucleolus

8128:LOC100691958
gene id: 8128:LOC100691958
uniprot id: I3JUB5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

8128:st3gal3
gene id: 8128:st3gal3
uniprot id: A0A669C5M1
uniprot id: A0A669D407
uniprot id: A0A669E1Y8
uniprot id: A0A669EQ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC106096484
gene id: 8128:LOC106096484
uniprot id: I3JRP3
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:noc3l
gene id: 8128:noc3l
uniprot id: A0A669F5I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

8128:LOC100692768
gene id: 8128:LOC100692768
uniprot id: A0A669CAV0
names: Subcellular Location Annotation
messages: Synapse

8128:rb1
gene id: 8128:rb1
uniprot id: I3J945
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

8128:fitm2
gene id: 8128:fitm2
uniprot id: I3KI53
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:LOC100697109
gene id: 8128:LOC100697109
uniprot id: A0A669EU62
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

8128:LOC100694886
gene id: 8128:LOC100694886
uniprot id: A0A669CXZ9
uniprot id: A0A669EHD2
uniprot id: A0A669EHZ6
uniprot id: I3JI29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

8128:LOC100689976
gene id: 8128:LOC100689976
uniprot id: A0A669FBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

8128:LOC100703626
gene id: 8128:LOC100703626
uniprot id: I3KQJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8128:map1lc3c
gene id: 8128:map1lc3c
uniprot id: I3JI36
names: Similarity
messages: Belongs to the ATG8 family.

8128:LOC100694417
gene id: 8128:LOC100694417
uniprot id: A0A669CZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

8128:LOC100697873
gene id: 8128:LOC100697873
uniprot id: A0A669CQZ4
uniprot id: I3JGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8128:sprn
gene id: 8128:sprn
uniprot id: I3L067
names: Similarity
messages: Belongs to the SPRN family.

8128:LOC100690051
gene id: 8128:LOC100690051
uniprot id: I3JJ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:LOC100709681
gene id: 8128:LOC100709681
uniprot id: I3JCU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

8128:LOC100697792
gene id: 8128:LOC100697792
uniprot id: A0A669AYE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

8128:LOC100700376
gene id: 8128:LOC100700376
uniprot id: A0A669CX23
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: nucleolus

8128:LOC100710389
gene id: 8128:LOC100710389
uniprot id: I3IYM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8128:LOC100700808
gene id: 8128:LOC100700808
uniprot id: A0A669BKY8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8128:slc45a3
gene id: 8128:slc45a3
uniprot id: I3JVM9
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100707215
gene id: 8128:LOC100707215
uniprot id: A0A669CYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100699060
gene id: 8128:LOC100699060
uniprot id: I3J3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:dusp26
gene id: 8128:dusp26
uniprot id: A0A669C6M4
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8128:LOC100692615
gene id: 8128:LOC100692615
uniprot id: I3K8T1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8128:LOC100700272
gene id: 8128:LOC100700272
uniprot id: A0A669CDS0
names: Subcellular Location Annotation
messages: Membrane

8128:serpinh1
gene id: 8128:serpinh1
uniprot id: I3JCG6
names: Similarity
messages: Belongs to the serpin family.

8128:fam160b1
gene id: 8128:fam160b1
uniprot id: I3JV87
names: Similarity
messages: Belongs to the FHIP family.

8128:LOC100702960
gene id: 8128:LOC100702960
uniprot id: I3JV69
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100697226
gene id: 8128:LOC100697226
uniprot id: A0A669DRS6
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

8128:LOC109195544
gene id: 8128:LOC109195544
uniprot id: A0A669E2J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8128:bcdin3d
gene id: 8128:bcdin3d
uniprot id: I3JIH4
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8128:tspan31
gene id: 8128:tspan31
uniprot id: I3KI97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:LOC100693232
gene id: 8128:LOC100693232
uniprot id: A0A669CJZ9
uniprot id: A0A669CN65
uniprot id: A0A669FCC7
names: Similarity
messages: Belongs to the SH3BGR family.

8128:LOC100709359
gene id: 8128:LOC100709359
uniprot id: I3JMB3
names: Similarity
messages: Belongs to the Rab GDI family.

8128:LOC100694413
gene id: 8128:LOC100694413
uniprot id: I3JXQ9
names: Similarity
messages: Belongs to the gonadal family.

8128:chrd
gene id: 8128:chrd
uniprot id: I3JXJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chordin family.
messages: Secreted

8128:egfr
gene id: 8128:egfr
uniprot id: A0A669AZ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8128:LOC100701956
gene id: 8128:LOC100701956
uniprot id: A0A669BA51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8128:LOC100700473
gene id: 8128:LOC100700473
uniprot id: A0A669CPX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8128:LOC100697780
gene id: 8128:LOC100697780
uniprot id: A0A669CAW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8128:mrps17
gene id: 8128:mrps17
uniprot id: A0A669BZI6
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8128:greb1l
gene id: 8128:greb1l
uniprot id: A0A669CRC9
uniprot id: I3JSI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

8128:LOC100690385
gene id: 8128:LOC100690385
uniprot id: I3KNP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8128:LOC100706083
gene id: 8128:LOC100706083
uniprot id: I3KPN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

8128:LOC100691670
gene id: 8128:LOC100691670
uniprot id: I3K415
names: Similarity
messages: Belongs to the actin family.

8128:ccm2
gene id: 8128:ccm2
uniprot id: I3KDX1
names: Similarity
messages: Belongs to the CCM2 family.

8128:harbi1
gene id: 8128:harbi1
uniprot id: I3KDF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

8128:LOC100696711
gene id: 8128:LOC100696711
uniprot id: A0A669BSX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100702439
gene id: 8128:LOC100702439
uniprot id: I3IXS8
names: Similarity
messages: Belongs to the IFI44 family.

8128:galnt2
gene id: 8128:galnt2
uniprot id: I3KK93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100699155
gene id: 8128:LOC100699155
uniprot id: I3IW09
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8128:LOC100706723
gene id: 8128:LOC100706723
uniprot id: I3IY14
names: Similarity
messages: Belongs to the serpin family.

8128:sucla2
gene id: 8128:sucla2
uniprot id: A0A669EGA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

8128:LOC100689983
gene id: 8128:LOC100689983
uniprot id: I3KZF5
names: Similarity
messages: Belongs to the BTG family.

8128:bmpr1b
gene id: 8128:bmpr1b
uniprot id: A0A669EGD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8128:LOC109196543
gene id: 8128:LOC109196543
uniprot id: A0A669DGI6
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709408
gene id: 8128:LOC100709408
uniprot id: A0A669EUL7
names: Similarity
messages: Belongs to the RRM Spen family.

8128:cyp1b1
gene id: 8128:cyp1b1
uniprot id: A0A669CWV0
uniprot id: F8TAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8128:LOC100704831
gene id: 8128:LOC100704831
uniprot id: I3KXW2
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100703711
gene id: 8128:LOC100703711
uniprot id: I3KDE2
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

8128:LOC102082933
gene id: 8128:LOC102082933
uniprot id: I3JNF8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100696848
gene id: 8128:LOC100696848
uniprot id: A0A669CZK4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100703020
gene id: 8128:LOC100703020
uniprot id: I3KTD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8128:LOC100689943
gene id: 8128:LOC100689943
uniprot id: I3KGW5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

8128:mettl1
gene id: 8128:mettl1
uniprot id: I3KSR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

8128:rnf34
gene id: 8128:rnf34
uniprot id: I3JXL7
uniprot id: I3JXL8
names: Subcellular Location Annotation
messages: Cell membrane

8128:ccndbp1
gene id: 8128:ccndbp1
uniprot id: A0A669C4M5
names: Similarity
messages: Belongs to the CCNDBP1 family.

8128:LOC100707734
gene id: 8128:LOC100707734
uniprot id: I3J8N5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8128:gng5
gene id: 8128:gng5
uniprot id: A0A669DQP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8128:taf4
gene id: 8128:taf4
uniprot id: A0A669ENR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8128:pgpep1
gene id: 8128:pgpep1
uniprot id: A0A669D0I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

8128:fabp1
gene id: 8128:fabp1
uniprot id: I3KDH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

8128:LOC100698783
gene id: 8128:LOC100698783
uniprot id: A0A669CL29
names: Similarity
messages: Belongs to the TGF-beta family.

8128:malrd1
gene id: 8128:malrd1
uniprot id: A0A669EL41
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:cdc45
gene id: 8128:cdc45
uniprot id: I3KAH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

8128:fdxr
gene id: 8128:fdxr
uniprot id: I3KUA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

8128:traf4
gene id: 8128:traf4
uniprot id: A0A4D6GPZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8128:taf11
gene id: 8128:taf11
uniprot id: I3KJX7
names: Similarity
messages: Belongs to the TAF11 family.

8128:lig4
gene id: 8128:lig4
uniprot id: I3K1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

8128:LOC100697270
gene id: 8128:LOC100697270
uniprot id: I3KHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100690319
gene id: 8128:LOC100690319
uniprot id: I3JJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:LOC100690564
gene id: 8128:LOC100690564
uniprot id: A0A669BI94
names: Similarity
messages: Belongs to the beta-catenin family.

8128:LOC100708570
gene id: 8128:LOC100708570
uniprot id: I3J023
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100696675
gene id: 8128:LOC100696675
uniprot id: I3JUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:LOC100707523
gene id: 8128:LOC100707523
uniprot id: A0A669CGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8128:LOC100690147
gene id: 8128:LOC100690147
uniprot id: A0A669CRF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

8128:LOC102080227
gene id: 8128:LOC102080227
uniprot id: A0A669B1J1
uniprot id: A0A669BRK7
names: Similarity
messages: Belongs to the CCSER family.

8128:ephb3
gene id: 8128:ephb3
uniprot id: I3K3N4
names: Subcellular Location Annotation
messages: Membrane

8128:lmln
gene id: 8128:lmln
uniprot id: I3KGT0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

8128:LOC100701936
gene id: 8128:LOC100701936
uniprot id: I3JB33
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:polr1e
gene id: 8128:polr1e
uniprot id: I3JQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

8128:loxhd1
gene id: 8128:loxhd1
uniprot id: I3JKU1
uniprot id: I3KDI6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:ndufb7
gene id: 8128:ndufb7
uniprot id: A0A669BHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

8128:p2ry2
gene id: 8128:p2ry2
uniprot id: A0A669DX53
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:adora2a
gene id: 8128:adora2a
uniprot id: A0A669BE31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8128:adra2a
gene id: 8128:adra2a
uniprot id: I3KZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100707594
gene id: 8128:LOC100707594
uniprot id: I3JW48
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

8128:anxa1
gene id: 8128:anxa1
uniprot id: I3JXB6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8128:LOC102081895
gene id: 8128:LOC102081895
uniprot id: I3KYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8128:LOC100707235
gene id: 8128:LOC100707235
uniprot id: I3KXQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8128:LOC100711263
gene id: 8128:LOC100711263
uniprot id: I3JFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:cnot9
gene id: 8128:cnot9
uniprot id: I3KJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

8128:LOC100697316
gene id: 8128:LOC100697316
uniprot id: A0A669E4V0
names: Similarity
messages: Belongs to the cystatin family.

8128:LOC100708288
gene id: 8128:LOC100708288
uniprot id: I3KGB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8128:hgd
gene id: 8128:hgd
uniprot id: A0A669E934
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

8128:upf2
gene id: 8128:upf2
uniprot id: I3KNH3
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100693547
gene id: 8128:LOC100693547
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:usp5
gene id: 8128:usp5
uniprot id: I3K5G9
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:ppp1r12a
gene id: 8128:ppp1r12a
uniprot id: A0A669C720
uniprot id: A0A669CET0
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

8128:snx17
gene id: 8128:snx17
uniprot id: I3KDS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8128:acy1
gene id: 8128:acy1
uniprot id: I3KAN0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm

8128:LOC100692560
gene id: 8128:LOC100692560
uniprot id: A0A669B9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

8128:LOC100690581
gene id: 8128:LOC100690581
uniprot id: I3JFB3
names: Subcellular Location Annotation
messages: Membrane

8128:ldhd
gene id: 8128:ldhd
uniprot id: A0A669BV53
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

8128:LOC100711270
gene id: 8128:LOC100711270
uniprot id: I3J173
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100703572
gene id: 8128:LOC100703572
uniprot id: I3KP21
names: Similarity
messages: Belongs to the MIF family.

8128:vps72
gene id: 8128:vps72
uniprot id: I3J3N5
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

8128:sdad1
gene id: 8128:sdad1
uniprot id: I3JL89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

8128:LOC100694382
gene id: 8128:LOC100694382
uniprot id: I3KPE7
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8128:adamts18
gene id: 8128:adamts18
uniprot id: I3J506
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8128:usp10
gene id: 8128:usp10
uniprot id: A0A669DJ10
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:LOC100691978
gene id: 8128:LOC100691978
uniprot id: A0A669B6C0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8128:siah1
gene id: 8128:siah1
uniprot id: A0A669CSE2
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

8128:LOC100692553
gene id: 8128:LOC100692553
uniprot id: I3KUG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

8128:LOC100700226
gene id: 8128:LOC100700226
uniprot id: I3JYS7
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100693545
gene id: 8128:LOC100693545
uniprot id: I3JFH9
names: Subcellular Location Annotation
messages: extracellular space

8128:zgpat
gene id: 8128:zgpat
uniprot id: I3JSC3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100706931
gene id: 8128:LOC100706931
uniprot id: I3KGP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8128:LOC100705573
gene id: 8128:LOC100705573
uniprot id: A0A669BJ82
names: Similarity
messages: Belongs to the sorting nexin family.

8128:LOC100711010
gene id: 8128:LOC100711010
uniprot id: I3KBF2
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8128:dhx58
gene id: 8128:dhx58
uniprot id: A0A669DVA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

8128:LOC100702754
gene id: 8128:LOC100702754
uniprot id: A0A669DXF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8128:LOC100702624
gene id: 8128:LOC100702624
uniprot id: A0A669E1Q0
names: Subcellular Location Annotation
messages: Membrane

8128:was
gene id: 8128:was
uniprot id: A0A669CQM5
names: Subcellular Location Annotation
messages: Nucleus

8128:tmem200a
gene id: 8128:tmem200a
uniprot id: I3IWA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

8128:LOC100694598
gene id: 8128:LOC100694598
uniprot id: A0A669D8Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8128:LOC100704477
gene id: 8128:LOC100704477
uniprot id: I3J525
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

8128:LOC100689993
gene id: 8128:LOC100689993
uniprot id: I3K5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

8128:kras
gene id: 8128:kras
uniprot id: I3KBN2
uniprot id: I3KBN3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:nt5dc1
gene id: 8128:nt5dc1
uniprot id: A0A669BL17
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

8128:naxe
gene id: 8128:naxe
uniprot id: I3K891
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted

8128:LOC102080969
gene id: 8128:LOC102080969
uniprot id: I3JIP5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:psmb7
gene id: 8128:psmb7
uniprot id: A0A669DHT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8128:dars2
gene id: 8128:dars2
uniprot id: I3KIK8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

8128:LOC100712528
gene id: 8128:LOC100712528
uniprot id: I3KD37
names: Similarity
messages: Belongs to the intermediate filament family.

8128:LOC100700877
gene id: 8128:LOC100700877
uniprot id: I3JBB9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8128:LOC100692119
gene id: 8128:LOC100692119
uniprot id: I3J5G4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

8128:dgkq
gene id: 8128:dgkq
uniprot id: I3J9C8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8128:LOC102078106
gene id: 8128:LOC102078106
uniprot id: A0A669D2Y5
names: Similarity
messages: Belongs to the mab-21 family.

8128:tnfrsf14
gene id: 8128:tnfrsf14
uniprot id: A0A0B5GTK7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100697126
gene id: 8128:LOC100697126
uniprot id: A0A669F4X8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100693008
gene id: 8128:LOC100693008
uniprot id: A0A669AZA4
uniprot id: A0A669F8R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

8128:LOC109194425
gene id: 8128:LOC109194425
uniprot id: I3KC98
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC102077949
gene id: 8128:LOC102077949
uniprot id: A0A669CA20
uniprot id: A0A669DVQ8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100696486
gene id: 8128:LOC100696486
uniprot id: I3K6D0
names: Similarity
messages: Belongs to the SKI family.

8128:kcnk2
gene id: 8128:kcnk2
uniprot id: I3K7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8128:exoc8
gene id: 8128:exoc8
uniprot id: I3KPK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

8128:LOC100690729
gene id: 8128:LOC100690729
uniprot id: I3JJV3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC100696271
gene id: 8128:LOC100696271
uniprot id: A0A669EGF5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8128:LOC100708026
gene id: 8128:LOC100708026
uniprot id: I3KXD4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:plxna1
gene id: 8128:plxna1
uniprot id: I3KTJ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC100699490
gene id: 8128:LOC100699490
uniprot id: I3KZY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

8128:fgf23
gene id: 8128:fgf23
uniprot id: I3ITT1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8128:LOC100704109
gene id: 8128:LOC100704109
uniprot id: A0A669CR79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

8128:gpatch1
gene id: 8128:gpatch1
uniprot id: I3J5K8
names: Similarity
messages: Belongs to the GPATCH1 family.

8128:pdgfd
gene id: 8128:pdgfd
uniprot id: A0A669CKV5
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100694011
gene id: 8128:LOC100694011
uniprot id: I3JXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8128:LOC100701934
gene id: 8128:LOC100701934
uniprot id: I3JEP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8128:b4galnt1
gene id: 8128:b4galnt1
uniprot id: A0A669F9R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

8128:usp32
gene id: 8128:usp32
uniprot id: A0A669F3S9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100699359
gene id: 8128:LOC100699359
uniprot id: A0A669B3P5
uniprot id: I3J316
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

8128:LOC100691094
gene id: 8128:LOC100691094
uniprot id: A0A669F306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

8128:madd
gene id: 8128:madd
uniprot id: A0A669E4L5
uniprot id: A0A669EVA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MADD family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8128:LOC106097520
gene id: 8128:LOC106097520
uniprot id: I3JI17
names: Similarity
messages: Belongs to the HEBP family.

8128:LOC100699442
gene id: 8128:LOC100699442
uniprot id: A0A669F208
names: Subcellular Location Annotation
messages: Membrane

8128:tacr3b
gene id: 8128:tacr3b
uniprot id: A0A075QUD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:LOC100700110
gene id: 8128:LOC100700110
uniprot id: A0A669CSR8
names: Similarity
messages: Belongs to the TAFA family.

8128:LOC100698509
gene id: 8128:LOC100698509
uniprot id: A0A669EW76
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100704624
gene id: 8128:LOC100704624
uniprot id: I3JDT8
uniprot id: I3JDT9
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8128:gpr157
gene id: 8128:gpr157
uniprot id: I3J2G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 5 family.
messages: Membrane

8128:pttg1
gene id: 8128:pttg1
uniprot id: I3J2T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

8128:slco5a1
gene id: 8128:slco5a1
uniprot id: I3K9V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8128:ppp2r5a
gene id: 8128:ppp2r5a
uniprot id: A0A669BMZ8
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8128:hbp1
gene id: 8128:hbp1
uniprot id: I3JPC3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

8128:LOC100694653
gene id: 8128:LOC100694653
uniprot id: A0A0E3M0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

8128:zdhhc12
gene id: 8128:zdhhc12
uniprot id: A0A669F6T0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8128:LOC106097781
gene id: 8128:LOC106097781
uniprot id: I3JXI2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:LOC100706041
gene id: 8128:LOC100706041
uniprot id: I3J1S7
names: Subcellular Location Annotation
messages: Membrane

8128:cog4
gene id: 8128:cog4
uniprot id: I3JEC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

8128:tat
gene id: 8128:tat
uniprot id: A0A669C3I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

8128:lancl2
gene id: 8128:lancl2
uniprot id: A0A669CM37
names: Similarity
messages: Belongs to the LanC-like protein family.

8128:LOC100699999
gene id: 8128:LOC100699999
uniprot id: A0A669CWP3
uniprot id: I3KWU5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8128:LOC100710659
gene id: 8128:LOC100710659
uniprot id: A0A669DDE5
names: Similarity
messages: Belongs to the cystatin family.

8128:LOC109203481
gene id: 8128:LOC109203481
uniprot id: A0A669F8D3
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100705124
gene id: 8128:LOC100705124
uniprot id: A0A669B5D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

8128:LOC100704269
gene id: 8128:LOC100704269
uniprot id: I3KHA7
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8128:eef2k
gene id: 8128:eef2k
uniprot id: A0A669CAB2
uniprot id: A0A669DWT5
uniprot id: A0A669EKG3
uniprot id: I3KFN5
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

8128:psmd12
gene id: 8128:psmd12
uniprot id: I3JH38
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

8128:ndrg4
gene id: 8128:ndrg4
uniprot id: A0A669C7E0
uniprot id: I3JXP2
names: Similarity
messages: Belongs to the NDRG family.

8128:LOC100696308
gene id: 8128:LOC100696308
uniprot id: A0A669CTW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

8128:LOC102080562
gene id: 8128:LOC102080562
uniprot id: A0A669DLD0
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100712454
gene id: 8128:LOC100712454
uniprot id: I3J3F9
names: Subcellular Location Annotation
messages: Nucleus

8128:hcrtr2
gene id: 8128:hcrtr2
uniprot id: I3JTL6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100690163
gene id: 8128:LOC100690163
uniprot id: I3KVC9
names: Similarity
messages: Belongs to the MAGUK family.

8128:pold2
gene id: 8128:pold2
uniprot id: I3JXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

8128:prickle1
gene id: 8128:prickle1
uniprot id: I3JQ05
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8128:LOC100704073
gene id: 8128:LOC100704073
uniprot id: A0A669BZE9
uniprot id: I3J461
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

8128:chst1
gene id: 8128:chst1
uniprot id: I3KXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8128:sap30l
gene id: 8128:sap30l
uniprot id: I3K696
names: Similarity
messages: Belongs to the SAP30 family.

8128:LOC100706999
gene id: 8128:LOC100706999
uniprot id: A0A669B9L6
uniprot id: I3IZI4
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8128:pde3b
gene id: 8128:pde3b
uniprot id: I3JFT7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100691939
gene id: 8128:LOC100691939
uniprot id: I3J4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8128:sdhc
gene id: 8128:sdhc
uniprot id: A0A669BB67
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

8128:neurl2
gene id: 8128:neurl2
uniprot id: A0A669CB11
uniprot id: A0A669EGH6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC100704236
gene id: 8128:LOC100704236
uniprot id: I3JE52
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100710151
gene id: 8128:LOC100710151
uniprot id: A0A669EDI5
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

8128:psmd13
gene id: 8128:psmd13
uniprot id: I3KER8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

8128:LOC100692673
gene id: 8128:LOC100692673
uniprot id: I3JMC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8128:caskin2
gene id: 8128:caskin2
uniprot id: I3KTW6
names: Subcellular Location Annotation
messages: Cytoplasm

8128:apoa4a
gene id: 8128:apoa4a
uniprot id: I3K841
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8128:LOC100707011
gene id: 8128:LOC100707011
uniprot id: I3JU43
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:LOC109194151
gene id: 8128:LOC109194151
uniprot id: A0A669BXF8
names: Similarity
messages: Belongs to the cullin family.

8128:LOC100705260
gene id: 8128:LOC100705260
uniprot id: I3KNC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

8128:taf7l
gene id: 8128:taf7l
uniprot id: I3J3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

8128:LOC100705611
gene id: 8128:LOC100705611
uniprot id: A0A669B5F8
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

8128:rps27a
gene id: 8128:rps27a
uniprot id: I3KGK5
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

8128:LOC100691074
gene id: 8128:LOC100691074
uniprot id: A0A669C5S5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100704409
gene id: 8128:LOC100704409
uniprot id: A0A669C3M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:tfap2c
gene id: 8128:tfap2c
uniprot id: I3JIA8
names: Similarity
messages: Belongs to the AP-2 family.

8128:slc35b2
gene id: 8128:slc35b2
uniprot id: A0A669FAV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8128:LOC100691505
gene id: 8128:LOC100691505
uniprot id: I3KIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

8128:LOC100534434
gene id: 8128:LOC100534434
uniprot id: A0A669FBS5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8128:trim62
gene id: 8128:trim62
uniprot id: I3J8E3
names: Subcellular Location Annotation
messages: Cytoplasm

8128:LOC102081675
gene id: 8128:LOC102081675
uniprot id: A0A669CKR7
names: Function
messages: May be involved in neurite outgrowth.

8128:LOC100711684
gene id: 8128:LOC100711684
uniprot id: A0A669B6H4
uniprot id: I3JQZ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:LOC100712199
gene id: 8128:LOC100712199
uniprot id: A0A669EA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:nptx1
gene id: 8128:nptx1
uniprot id: A0A669CFB1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100695900
gene id: 8128:LOC100695900
uniprot id: I3J570
names: Similarity
messages: Belongs to the RRM elav family.

8128:LOC100704838
gene id: 8128:LOC100704838
uniprot id: A0A669DJA2
uniprot id: I3K434
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8128:LOC100710839
gene id: 8128:LOC100710839
uniprot id: A0A669F5H5
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

8128:ube2k
gene id: 8128:ube2k
uniprot id: I3JR41
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8128:LOC100711569
gene id: 8128:LOC100711569
uniprot id: A0A669DFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8128:LOC100690161
gene id: 8128:LOC100690161
uniprot id: I3KU67
names: Similarity
messages: Belongs to the JIP scaffold family.

8128:LOC100693441
gene id: 8128:LOC100693441
uniprot id: A0A669BX03
uniprot id: A0A669CQB4
uniprot id: A0A669CUG3
uniprot id: A0A669F5Y7
uniprot id: I3JVW2
names: Subcellular Location Annotation
messages: cytoskeleton

8128:nxpe3
gene id: 8128:nxpe3
uniprot id: I3K9Y4
names: Similarity
messages: Belongs to the NXPE family.

8128:LOC100707807
gene id: 8128:LOC100707807
uniprot id: I3JU83
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

8128:mapk8ip2
gene id: 8128:mapk8ip2
uniprot id: A0A669CCB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

8128:ncaph
gene id: 8128:ncaph
uniprot id: I3KGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

8128:LOC102082963
gene id: 8128:LOC102082963
uniprot id: A0A669DMA8
names: Similarity
messages: Belongs to the NXPE family.

8128:LOC100697937
gene id: 8128:LOC100697937
uniprot id: I3JPJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

8128:ctsh
gene id: 8128:ctsh
uniprot id: A0A669EHD4
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:camsap2
gene id: 8128:camsap2
uniprot id: I3K3U5
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8128:LOC100706624
gene id: 8128:LOC100706624
uniprot id: I3K4S3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:tnpo1
gene id: 8128:tnpo1
uniprot id: A0A669D5D7
names: Subcellular Location Annotation
messages: Cytoplasm

8128:thyn1
gene id: 8128:thyn1
uniprot id: I3JYR7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8128:LOC100691738
gene id: 8128:LOC100691738
uniprot id: I3JHD7
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

8128:srp9
gene id: 8128:srp9
uniprot id: A0A669F103
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

8128:LOC100711948
gene id: 8128:LOC100711948
uniprot id: A0A669DKI6
names: Similarity
messages: Belongs to the actin family.

8128:LOC100699899
gene id: 8128:LOC100699899
uniprot id: I3K4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8128:tmc8
gene id: 8128:tmc8
uniprot id: I3KRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8128:LOC100699273
gene id: 8128:LOC100699273
uniprot id: I3IU30
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100712047
gene id: 8128:LOC100712047
uniprot id: A0A669BFE6
uniprot id: I3IWU2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8128:LOC100692497
gene id: 8128:LOC100692497
uniprot id: A0A669CZ87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:klhl3
gene id: 8128:klhl3
uniprot id: A0A669AW87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KLHL3 family.
messages: cytoskeleton
messages: cytosol

8128:LOC100695541
gene id: 8128:LOC100695541
uniprot id: A0A669BWP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

8128:LOC100693003
gene id: 8128:LOC100693003
uniprot id: I3JFF4
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100695295
gene id: 8128:LOC100695295
uniprot id: I3J1F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:hdac6
gene id: 8128:hdac6
uniprot id: I3IWS1
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

8128:LOC100704599
gene id: 8128:LOC100704599
uniprot id: A0A669EGQ0
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

8128:minar1
gene id: 8128:minar1
uniprot id: A0A669BE11
names: Similarity
messages: Belongs to the MINAR family.

8128:LOC100699350
gene id: 8128:LOC100699350
uniprot id: A0A669DNZ3
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC109204179
gene id: 8128:LOC109204179
uniprot id: A0A669DL86
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:draxin
gene id: 8128:draxin
uniprot id: I3IVY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.
messages: Secreted

8128:rnf10
gene id: 8128:rnf10
uniprot id: A0A669E8Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

8128:LOC100711499
gene id: 8128:LOC100711499
uniprot id: I3JY48
names: Similarity
messages: Belongs to the BRINP family.

8128:sf3b1
gene id: 8128:sf3b1
uniprot id: I3K862
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

8128:LOC100698856
gene id: 8128:LOC100698856
uniprot id: A0A669BWP5
uniprot id: A0A669CH39
uniprot id: A0A669ER05
uniprot id: A0A669FA77
uniprot id: I3KCI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

8128:pde8a
gene id: 8128:pde8a
uniprot id: I3IUG8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8128:LOC100705554
gene id: 8128:LOC100705554
uniprot id: A0A669DBD5
names: Subcellular Location Annotation
messages: Membrane

8128:grhl3
gene id: 8128:grhl3
uniprot id: I3J6D4
names: Subcellular Location Annotation
messages: Nucleus

8128:frg1
gene id: 8128:frg1
uniprot id: I3JV86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

8128:apex2
gene id: 8128:apex2
uniprot id: I3KJI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

8128:LOC100691526
gene id: 8128:LOC100691526
uniprot id: I3IWP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8128:fbxl5
gene id: 8128:fbxl5
uniprot id: I3J4U0
names: Subcellular Location Annotation
messages: perinuclear region

8128:LOC100696275
gene id: 8128:LOC100696275
uniprot id: A0A669EB55
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

8128:LOC100700541
gene id: 8128:LOC100700541
uniprot id: I3IXF4
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100703119
gene id: 8128:LOC100703119
uniprot id: I3IXB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8128:rad51
gene id: 8128:rad51
uniprot id: Q50LF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

8128:fam163a
gene id: 8128:fam163a
uniprot id: I3K9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8128:LOC100698715
gene id: 8128:LOC100698715
uniprot id: I3JWL1
names: Similarity
messages: Belongs to the GADD45 family.

8128:LOC100704193
gene id: 8128:LOC100704193
uniprot id: I3KDI2
names: Similarity
messages: Belongs to the IUNH family.

8128:lrrc8a
gene id: 8128:lrrc8a
uniprot id: I3JKB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8128:LOC100704882
gene id: 8128:LOC100704882
uniprot id: A0A669B8B4
uniprot id: I3JQU0
names: Similarity
messages: Belongs to the WAL family.

8128:LOC100700916
gene id: 8128:LOC100700916
uniprot id: I3J7W7
names: Similarity
messages: Belongs to the SKI family.

8128:LOC109196647
gene id: 8128:LOC109196647
uniprot id: I3JXP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8128:ptgdsl1
gene id: 8128:ptgdsl1
uniprot id: I3JC83
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8128:LOC100695852
gene id: 8128:LOC100695852
uniprot id: A0A669BFS5
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

8128:LOC102080448
gene id: 8128:LOC102080448
uniprot id: A0A669EU93
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8128:LOC100690079
gene id: 8128:LOC100690079
uniprot id: I3J5W1
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

8128:LOC100692296
gene id: 8128:LOC100692296
uniprot id: A0A669ECX7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:lrit1
gene id: 8128:lrit1
uniprot id: I3KGH9
names: Subcellular Location Annotation
messages: Membrane

8128:grk7
gene id: 8128:grk7
uniprot id: I3JWW1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8128:LOC100693006
gene id: 8128:LOC100693006
uniprot id: I3KX66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8128:ptpn11
gene id: 8128:ptpn11
uniprot id: I3KDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

8128:ubr3
gene id: 8128:ubr3
uniprot id: I3JQ82
uniprot id: I3JQ83
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

8128:bbox1
gene id: 8128:bbox1
uniprot id: I3JET2
names: Function
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.

8128:cdca5
gene id: 8128:cdca5
uniprot id: I3K7P4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8128:LOC100706119
gene id: 8128:LOC100706119
uniprot id: I3KBF1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:wars
gene id: 8128:wars
uniprot id: A0A669BRQ2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8128:LOC100706002
gene id: 8128:LOC100706002
uniprot id: A0A669FAW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8128:uchl3
gene id: 8128:uchl3
uniprot id: A0A669DP76
names: Similarity
messages: Belongs to the peptidase C12 family.

8128:cdca7l
gene id: 8128:cdca7l
uniprot id: I3JXT6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:slc35f3
gene id: 8128:slc35f3
uniprot id: A0A669D128
uniprot id: A0A669DQM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

8128:LOC100694793
gene id: 8128:LOC100694793
uniprot id: I3KY04
names: Similarity
messages: Belongs to the mTERF family.

8128:ampd1
gene id: 8128:ampd1
uniprot id: I3JS50
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

8128:LOC100709059
gene id: 8128:LOC100709059
uniprot id: A0A669FC63
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8128:pappa2
gene id: 8128:pappa2
uniprot id: I3KIP7
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100700742
gene id: 8128:LOC100700742
uniprot id: I3KYH9
names: Subcellular Location Annotation
messages: Membrane

8128:tie1
gene id: 8128:tie1
uniprot id: A0A669EDC0
uniprot id: A0A669ENI6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8128:cenpl
gene id: 8128:cenpl
uniprot id: I3K2A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

8128:ugt8
gene id: 8128:ugt8
uniprot id: A0A669E1K9
uniprot id: I3KB76
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

8128:LOC100707392
gene id: 8128:LOC100707392
uniprot id: A0A669BQK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

8128:LOC100695086
gene id: 8128:LOC100695086
uniprot id: A0A669B7K3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100700751
gene id: 8128:LOC100700751
uniprot id: A0A669B9Z2
uniprot id: A0A669BA21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

8128:LOC100704504
gene id: 8128:LOC100704504
uniprot id: I3IY31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

8128:grhpr
gene id: 8128:grhpr
uniprot id: I3JQS5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8128:impact
gene id: 8128:impact
uniprot id: I3J417
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

8128:slc19a1
gene id: 8128:slc19a1
uniprot id: I3IX33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

8128:aifm1
gene id: 8128:aifm1
uniprot id: I3K501
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

8128:gapdhs
gene id: 8128:gapdhs
uniprot id: G3LHF4
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

8128:hhex
gene id: 8128:hhex
uniprot id: I3JJU3
names: Subcellular Location Annotation
messages: Nucleus

8128:tns3
gene id: 8128:tns3
uniprot id: I3JTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

8128:tekt4
gene id: 8128:tekt4
uniprot id: I3KMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8128:LOC100701291
gene id: 8128:LOC100701291
uniprot id: I3IXP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

8128:LOC100707786
gene id: 8128:LOC100707786
uniprot id: I3KZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8128:mfsd14a
gene id: 8128:mfsd14a
uniprot id: A0A669DUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8128:LOC100702909
gene id: 8128:LOC100702909
uniprot id: A0A669D7Y4
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8128:stpg1
gene id: 8128:stpg1
uniprot id: I3K7V1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100706088
gene id: 8128:LOC100706088
uniprot id: A0A669AY67
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100701647
gene id: 8128:LOC100701647
uniprot id: A0A669C5I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

8128:rad52
gene id: 8128:rad52
uniprot id: I3KC09
names: Similarity
messages: Belongs to the RAD52 family.

8128:LOC100711007
gene id: 8128:LOC100711007
uniprot id: I3K5C9
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

8128:LOC100695703
gene id: 8128:LOC100695703
uniprot id: I3JK95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

8128:atp11c
gene id: 8128:atp11c
uniprot id: A0A669BHK2
uniprot id: A0A669E1U5
uniprot id: A0A669F0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8128:mrps25
gene id: 8128:mrps25
uniprot id: I3KKU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

8128:dclk2
gene id: 8128:dclk2
uniprot id: A0A669AX13
uniprot id: I3JUS4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8128:LOC100694563
gene id: 8128:LOC100694563
uniprot id: A0A669C2Y3
names: Similarity
messages: Belongs to the PP2C family.

8128:LOC100706831
gene id: 8128:LOC100706831
uniprot id: A0A669D258
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

8128:hoxc4
gene id: 8128:hoxc4
uniprot id: I3K2S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8128:LOC100694244
gene id: 8128:LOC100694244
uniprot id: A0A669C7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8128:LOC100710910
gene id: 8128:LOC100710910
uniprot id: A0A669AZA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8128:cystm1
gene id: 8128:cystm1
uniprot id: A0A669BQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

8128:LOC100702543
gene id: 8128:LOC100702543
uniprot id: I3JQ47
names: Subcellular Location Annotation
messages: Membrane

8128:tex10
gene id: 8128:tex10
uniprot id: I3JFH1
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

8128:LOC100703462
gene id: 8128:LOC100703462
uniprot id: A0A669BD99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

8128:LOC100692376
gene id: 8128:LOC100692376
uniprot id: I3K031
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8128:LOC100711782
gene id: 8128:LOC100711782
uniprot id: I3IWT4
names: Similarity
messages: Belongs to the FHIP family.

8128:fundc1
gene id: 8128:fundc1
uniprot id: I3KHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

8128:kitlg
gene id: 8128:kitlg
uniprot id: I3J7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

8128:LOC100700253
gene id: 8128:LOC100700253
uniprot id: A0A669DKL4
names: Similarity
messages: Belongs to the TAFA family.

8128:fat2
gene id: 8128:fat2
uniprot id: A0A669EXV3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:kcnj2
gene id: 8128:kcnj2
uniprot id: I3KZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

8128:LOC100692869
gene id: 8128:LOC100692869
uniprot id: I3JTA0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8128:LOC100697979
gene id: 8128:LOC100697979
uniprot id: I3JWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8128:LOC100695864
gene id: 8128:LOC100695864
uniprot id: I3JSV4
names: Similarity
messages: Belongs to the peptidase C19 family.

8128:tgfb1i1
gene id: 8128:tgfb1i1
uniprot id: A0A669E5I7
uniprot id: I3K059
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
messages: Nucleus matrix
messages: The LD (leucine and aspartate-rich) motif 3 mediates interaction with GIT1 and functions as a nuclear export signal.
messages: cytoskeleton
messages: focal adhesion

8128:pex12
gene id: 8128:pex12
uniprot id: I3JGM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.
messages: Membrane
messages: Peroxisome membrane

8128:LOC100703912
gene id: 8128:LOC100703912
uniprot id: A0A669CMX6
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8128:itga8
gene id: 8128:itga8
uniprot id: I3J4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8128:LOC100708615
gene id: 8128:LOC100708615
uniprot id: I3JCB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8128:tmcc1
gene id: 8128:tmcc1
uniprot id: A0A669CVM5
uniprot id: A0A669EZC3
uniprot id: A0A669F5F3
uniprot id: I3KKT5
names: Similarity
messages: Belongs to the TEX28 family.

8128:LOC100694359
gene id: 8128:LOC100694359
uniprot id: A0A669ERR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

8128:cdk7
gene id: 8128:cdk7
uniprot id: I3K805
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

8128:LOC100697276
gene id: 8128:LOC100697276
uniprot id: A0A669D414
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

8128:cnih2
gene id: 8128:cnih2
uniprot id: I3J009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8128:kiaa2013
gene id: 8128:kiaa2013
uniprot id: I3KNG1
names: Subcellular Location Annotation
messages: Membrane

8128:hrh1
gene id: 8128:hrh1
uniprot id: I3KX93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8128:LOC100700667
gene id: 8128:LOC100700667
uniprot id: I3KAC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8128:ndufa13
gene id: 8128:ndufa13
uniprot id: I3JV91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

8128:LOC100702291
gene id: 8128:LOC100702291
uniprot id: I3ITT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

8128:LOC100699736
gene id: 8128:LOC100699736
uniprot id: A0A669B2C3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8128:LOC102083135
gene id: 8128:LOC102083135
uniprot id: I3KYX4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8128:LOC100696396
gene id: 8128:LOC100696396
uniprot id: I3JVP9
names: Subcellular Location Annotation
messages: Nucleus

8128:ufl1
gene id: 8128:ufl1
uniprot id: I3JZG7
names: Similarity
messages: Belongs to the UFL1 family.

8128:bop1
gene id: 8128:bop1
uniprot id: A0A669ERK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

8128:LOC100692626
gene id: 8128:LOC100692626
uniprot id: I3IV56
names: Similarity
messages: Belongs to the R-spondin family.

8128:LOC100708554
gene id: 8128:LOC100708554
uniprot id: A0A669BY67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.
messages: Cytoplasm

8128:cd79b
gene id: 8128:cd79b
uniprot id: I3JM38
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8128:phkg1
gene id: 8128:phkg1
uniprot id: A0A669BPZ9
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

8128:prdm12
gene id: 8128:prdm12
uniprot id: I3J405
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

8128:LOC100709564
gene id: 8128:LOC100709564
uniprot id: A0A669DWK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8128:LOC100709067
gene id: 8128:LOC100709067
uniprot id: I3JC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

8128:LOC100699256
gene id: 8128:LOC100699256
uniprot id: A0A669BNM2
uniprot id: A0A669EZB3
uniprot id: I3KJT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8128:LOC100705212
gene id: 8128:LOC100705212
uniprot id: A0A669C014
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

8128:LOC100694127
gene id: 8128:LOC100694127
uniprot id: A0A669EKB9
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8128:khsrp
gene id: 8128:khsrp
uniprot id: I3J1F5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC109201903
gene id: 8128:LOC109201903
uniprot id: A0A669DXY9
names: Similarity
messages: Belongs to the globin family.

8128:LOC100707990
gene id: 8128:LOC100707990
uniprot id: I3JBG0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8128:ndufaf1
gene id: 8128:ndufaf1
uniprot id: I3KU85
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

8128:LOC100698021
gene id: 8128:LOC100698021
uniprot id: I3J4W0
names: Subcellular Location Annotation
messages: extracellular space

8128:LOC100711905
gene id: 8128:LOC100711905
uniprot id: I3KYM1
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

8128:rbck1
gene id: 8128:rbck1
uniprot id: I3JI92
names: Similarity
messages: Belongs to the RBR family.

8128:dis3l2
gene id: 8128:dis3l2
uniprot id: A0A669EYN0
uniprot id: I3KQX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

8128:parvg
gene id: 8128:parvg
uniprot id: I3JQA9
names: Similarity
messages: Belongs to the parvin family.

8128:edc4
gene id: 8128:edc4
uniprot id: I3JYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

8128:LOC100702625
gene id: 8128:LOC100702625
uniprot id: A0A669E463
names: Subcellular Location Annotation
messages: Membrane

8128:mbtps1
gene id: 8128:mbtps1
uniprot id: A0A669BKZ2
names: Similarity
messages: Belongs to the peptidase S8 family.

8128:vps28
gene id: 8128:vps28
uniprot id: A0A669CRL8
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

8128:LOC106097004
gene id: 8128:LOC106097004
uniprot id: I3J379
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:pex1
gene id: 8128:pex1
uniprot id: I3J1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: cytosol

8128:LOC100703030
gene id: 8128:LOC100703030
uniprot id: A0A669E9Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

8128:nsa2
gene id: 8128:nsa2
uniprot id: A0A669B0F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

8128:wisp1
gene id: 8128:wisp1
uniprot id: I3J188
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8128:drc1
gene id: 8128:drc1
uniprot id: A0A669DW09
uniprot id: I3K6F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC1 family.
messages: cilium axoneme
messages: flagellum axoneme

8128:tmem132e
gene id: 8128:tmem132e
uniprot id: I3K6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8128:pik3r1
gene id: 8128:pik3r1
uniprot id: A0A669ESG1
uniprot id: A0A669EZC8
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

8128:LOC102078242
gene id: 8128:LOC102078242
uniprot id: A0A669DHZ1
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse

8128:LOC100702028
gene id: 8128:LOC100702028
uniprot id: A0A669FBL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8128:LOC100711626
gene id: 8128:LOC100711626
uniprot id: A0A669AX74
uniprot id: A0A669AZ12
uniprot id: I3KV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

8128:prdm15
gene id: 8128:prdm15
uniprot id: I3JZJ5
names: Subcellular Location Annotation
messages: Nucleus

8128:LOC100699379
gene id: 8128:LOC100699379
uniprot id: A0A669C8T4
uniprot id: A0A669E6T6
uniprot id: I3KT94
names: Similarity
messages: Belongs to the IUNH family.

8128:LOC100696153
gene id: 8128:LOC100696153
uniprot id: A0A669EJQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8128:LOC100696649
gene id: 8128:LOC100696649
uniprot id: I3JMH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

8128:LOC100694836
gene id: 8128:LOC100694836
uniprot id: P62796
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-6 (H4K5ac), Lys-9 (H4K8ac), Lys-13 (H4K12ac) and Lys-17 (H4K16ac) occurs in coding regions of the genome but not in heterochromatin.
messages: Belongs to the histone H4 family.
messages: Butyrylation of histones marks active promoters and competes with histone acetylation.
messages: Chromosome
messages: Citrullination at Arg-4 (H4R3ci) by PADI4 impairs methylation.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Glutarylation at Lys-92 (H4K91glu) destabilizes nucleosomes by promoting dissociation of the H2A-H2B dimers from nucleosomes.
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated, dimethylated or trimethylated at Lys-21 (H4K20me1, H4K20me2, H4K20me3). Monomethylation is performed by KMT5A/SET8. Trimethylation is performed by KMT5B and KMT5C and induces gene silencing. Monomethylated at Lys-13 (H4K12me1) by N6AMT1; H4K12me1 modification is present at the promoters of numerous genes encoding cell cycle regulators.
messages: Monomethylation and asymmetric dimethylation at Arg-4 (H4R3me1 and H4R3me2a, respectively) by PRMT1 favors acetylation at Lys-9 (H4K8ac) and Lys-13 (H4K12ac). Demethylation is performed by JMJD6. Symmetric dimethylation on Arg-4 (H4R3me2s) by the PRDM1/PRMT5 complex may play a crucial role in the germ-cell lineage (By similarity).
messages: Nucleus
messages: Phosphorylated by pak2 at Ser-48 (H4S47ph). This phosphorylation increases the association of H3.3-H4 with the histone chaperone HIRA, thus promoting nucleosome assembly of H3.3-H4 and inhibiting nucleosome assembly of H3.1-H4 (By similarity).
messages: Sumoylated, which is associated with transcriptional repression.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins. Monoubiquitinated at Lys-92 of histone H4 (H4K91ub1) in response to DNA damage. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 Lys-21 methylation (H4K20me) (By similarity).
messages: Ufmylated; monofmylated by UFL1 at Lys-32 (H4K31Ufm1) in response to DNA damage.

8128:LOC100703406
gene id: 8128:LOC100703406
uniprot id: I3JXR1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:kdm4a
gene id: 8128:kdm4a
uniprot id: A0A669EZ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

8128:engase
gene id: 8128:engase
uniprot id: I3JG51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

8128:LOC100691206
gene id: 8128:LOC100691206
uniprot id: I3KUU2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:kif11
gene id: 8128:kif11
uniprot id: I3KEB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
messages: spindle pole

8128:ca7
gene id: 8128:ca7
uniprot id: I3J4Q6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8128:LOC102078041
gene id: 8128:LOC102078041
uniprot id: I3KYA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

8128:hpn
gene id: 8128:hpn
uniprot id: I3JJX2
names: Subcellular Location Annotation
messages: extracellular space

8128:myo1e
gene id: 8128:myo1e
uniprot id: A0A669BI99
uniprot id: I3JES6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8128:LOC100692310
gene id: 8128:LOC100692310
uniprot id: A0A669EYP0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8128:LOC100711989
gene id: 8128:LOC100711989
uniprot id: I3J3Z0
names: Similarity
messages: Belongs to the peptidase C1 family.

8128:LOC100703929
gene id: 8128:LOC100703929
uniprot id: I3JDY5
names: Subcellular Location Annotation
messages: Membrane

8128:tmem163
gene id: 8128:tmem163
uniprot id: I3K1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

8128:LOC100703873
gene id: 8128:LOC100703873
uniprot id: A0A669D6J1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

8128:tbpl1
gene id: 8128:tbpl1
uniprot id: I3IVC7
names: Similarity
messages: Belongs to the TBP family.

8128:kri1
gene id: 8128:kri1
uniprot id: I3JNA1
names: Similarity
messages: Belongs to the KRI1 family.

8128:LOC100696514
gene id: 8128:LOC100696514
uniprot id: A0A669F8J7
uniprot id: I3IWZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

8128:LOC100694535
gene id: 8128:LOC100694535
uniprot id: A0A669BUY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8128:LOC100695765
gene id: 8128:LOC100695765
uniprot id: I3JQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8128:LOC100701297
gene id: 8128:LOC100701297
uniprot id: A0A669C565
names: Subcellular Location Annotation
messages: Nucleus

8128:taf6l
gene id: 8128:taf6l
uniprot id: A0A669CRG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8128:LOC100699754
gene id: 8128:LOC100699754
uniprot id: A0A669BXL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8128:col4a3bp
gene id: 8128:col4a3bp
uniprot id: A0A669EQM7
uniprot id: I3KGS5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

8128:LOC100711736
gene id: 8128:LOC100711736
uniprot id: A0A669DTE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Oligomer.

8128:LOC100695816
gene id: 8128:LOC100695816
uniprot id: A0A669EIK7
names: Similarity
messages: Belongs to the cytochrome P450 family.

8128:LOC102082086
gene id: 8128:LOC102082086
uniprot id: A0A669B6L7
names: Similarity
messages: Belongs to the ARTD/PARP family.

8128:LOC100693354
gene id: 8128:LOC100693354
uniprot id: A0A669B126
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8128:slc7a6os
gene id: 8128:slc7a6os
uniprot id: I3J552
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

8128:LOC100698352
gene id: 8128:LOC100698352
uniprot id: A0A669C9I8
names: Similarity
messages: Belongs to the DEAD box helicase family.

8128:LOC100700052
gene id: 8128:LOC100700052
uniprot id: I3JLS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

8128:shroom2
gene id: 8128:shroom2
uniprot id: I3J536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

8128:LOC100705785
gene id: 8128:LOC100705785
uniprot id: A0A669CIM6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

8128:LOC100706474
gene id: 8128:LOC100706474
uniprot id: I3KM71
names: Subcellular Location Annotation
messages: Nucleus

8128:bcl7b
gene id: 8128:bcl7b
uniprot id: A0A669B7B9
uniprot id: I3JE77
names: Similarity
messages: Belongs to the BCL7 family.

8128:LOC100696241
gene id: 8128:LOC100696241
uniprot id: A0A669CPN9
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8128:mtnr1a
gene id: 8128:mtnr1a
uniprot id: I3JV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8128:LOC100711480
gene id: 8128:LOC100711480
uniprot id: I3KMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8128:taf10
gene id: 8128:taf10
uniprot id: I3J126
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

8128:LOC100702317
gene id: 8128:LOC100702317
uniprot id: A0A669CSY5
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100711201
gene id: 8128:LOC100711201
uniprot id: A0A669E4W4
names: Subcellular Location Annotation
messages: Membrane

8128:nox4
gene id: 8128:nox4
uniprot id: A0A669CZQ9
uniprot id: A0A669EG85
names: Subcellular Location Annotation
messages: Membrane

8128:LOC100709916
gene id: 8128:LOC100709916
uniprot id: A0A669BWE6
names: Similarity
messages: Belongs to the peptidase C2 family.

8128:LOC100693371
gene id: 8128:LOC100693371
uniprot id: A0A669BJQ6
uniprot id: I3KUH4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus