8090:LOC101164849
gene id: 8090:LOC101164849
uniprot id: A0A3B3HU38
names: Similarity
messages: Belongs to the FAM53 family.

8090:slc41a2
gene id: 8090:slc41a2
uniprot id: H2M8Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8090:LOC101175367
gene id: 8090:LOC101175367
uniprot id: A0A3B3IED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8090:LOC101164886
gene id: 8090:LOC101164886
uniprot id: H2LMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

8090:sdhaf2
gene id: 8090:sdhaf2
uniprot id: A0A3P9KTJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

8090:mrpl51
gene id: 8090:mrpl51
uniprot id: A0A3B3ID77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.
messages: Mitochondrion

8090:pde4d
gene id: 8090:pde4d
uniprot id: A0A3B3HW19
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8090:LOC101167273
gene id: 8090:LOC101167273
uniprot id: A0A3B3I196
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8090:LOC101173217
gene id: 8090:LOC101173217
uniprot id: A0A3B3HLN4
uniprot id: A0A3P9IU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

8090:LOC100125537
gene id: 8090:LOC100125537
uniprot id: H2LX36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:gmpr
gene id: 8090:gmpr
uniprot id: A0A3P9I1F3
uniprot id: H2MCQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

8090:LOC101167683
gene id: 8090:LOC101167683
uniprot id: A0A3B3HW49
names: Similarity
messages: Belongs to the TPPP family.

8090:ptpe
gene id: 8090:ptpe
uniprot id: Q76K57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

8090:LOC101174084
gene id: 8090:LOC101174084
uniprot id: A0A3P9KJW9
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101161480
gene id: 8090:LOC101161480
uniprot id: H2LFB8
names: Subcellular Location Annotation
messages: Membrane

8090:sars
gene id: 8090:sars
uniprot id: H2L7V1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

8090:LOC100125516
gene id: 8090:LOC100125516
uniprot id: A0A3B3II40
uniprot id: A0A3P9HVG3
uniprot id: H2MKN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8090:spen
gene id: 8090:spen
uniprot id: H2MW31
names: Similarity
messages: Belongs to the RRM Spen family.

8090:rsad1
gene id: 8090:rsad1
uniprot id: H2LSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

8090:LOC105357992
gene id: 8090:LOC105357992
uniprot id: A0A3B3HQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101170545
gene id: 8090:LOC101170545
uniprot id: H2MHJ1
names: Similarity
messages: Belongs to the ZC3H12 family.

8090:scfd2
gene id: 8090:scfd2
uniprot id: H2L494
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8090:abcd3
gene id: 8090:abcd3
uniprot id: H2LGA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

8090:LOC101167058
gene id: 8090:LOC101167058
uniprot id: A0A3P9IYK4
uniprot id: H2L9Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:atp23
gene id: 8090:atp23
uniprot id: H2LZ30
names: Similarity
messages: Belongs to the peptidase M76 family.

8090:six3
gene id: 8090:six3
uniprot id: A0A3P9JLL4
uniprot id: B0R222
uniprot id: O73916
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Interacts with GMNN.
messages: Nucleus
messages: Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes. During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon. Acts as a direct upstream activator of SHH expression in the rostral diencephalon ventral midline and that in turn SHH maintains its expression. In addition, Six3 activity is required for the formation of the telencephalon. During postnatal stages of brain development is necessary for ependymal cell maturation by promoting the maturation of radial glia into ependymal cells through regulation of neuroblast proliferation and migration. Acts on the proliferation and differentiation of neural progenitor cells through activating transcription of CCND1 and CCND2. During early lens formation plays a role in lens induction and specification by activating directly PAX6 in the presumptive lens ectoderm. In turn PAX6 activates SIX3 resulting in activation of PDGFRA and CCND1 promoting cell proliferation. Also is required for the neuroretina development by directly suppressing WNT8B expression in the anterior neural plate territory. Its action during retina development and lens morphogenesis is AES and TLE4-dependent manner. Furthermore, during eye development regulates several genes expression. Before and during early lens development represses the CRYGF promoter by binding a SIX repressor element. Directly activates RHO transcription, or cooperates with CRX or NRL. Six3 functions also in the formation of the proximodistal axis of the optic cup, and promotes the formation of optic vesicles-like structures. During pituitary development, acts in parallel or alternatively with HESX1 to control cell proliferation through Wnt/beta-catenin pathway. Plays a role in eye development by suppressing WNT…

8090:cdc42ep4
gene id: 8090:cdc42ep4
uniprot id: H2M621
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8090:LOC101163294
gene id: 8090:LOC101163294
uniprot id: H2MUV0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8090:zic1
gene id: 8090:zic1
uniprot id: Q7T1Q7
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8090:dusp1
gene id: 8090:dusp1
uniprot id: H2LQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8090:LOC101162386
gene id: 8090:LOC101162386
uniprot id: H2LQZ2
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101155685
gene id: 8090:LOC101155685
uniprot id: A0A3P9M6X1
uniprot id: H2LMD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

8090:LOC101162995
gene id: 8090:LOC101162995
uniprot id: A0A3B3HI46
names: Similarity
messages: Belongs to the BRINP family.

8090:shcbp1
gene id: 8090:shcbp1
uniprot id: H2MVR0
names: Subcellular Location Annotation
messages: spindle

8090:nus1
gene id: 8090:nus1
uniprot id: H2MKV9
names: Similarity
messages: Belongs to the UPP synthase family.

8090:elf4
gene id: 8090:elf4
uniprot id: A0A3B3HJJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:surf4
gene id: 8090:surf4
uniprot id: A0A3B3IGM1
uniprot id: A0A3P9ML75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101161532
gene id: 8090:LOC101161532
uniprot id: A0A3P9MNP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101156766
gene id: 8090:LOC101156766
uniprot id: H2LJ38
names: Similarity
messages: Belongs to the NDRG family.

8090:irf6
gene id: 8090:irf6
uniprot id: H2L4D8
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC105355967
gene id: 8090:LOC105355967
uniprot id: A0A3B3HKY9
names: Subcellular Location Annotation
messages: Membrane

8090:emc6
gene id: 8090:emc6
uniprot id: A0A3P9L8U6
uniprot id: H2M7D1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:wnt6
gene id: 8090:wnt6
uniprot id: H2MVL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8090:tada3
gene id: 8090:tada3
uniprot id: H2MDZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

8090:ggt1a
gene id: 8090:ggt1a
uniprot id: F1C7I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8090:gpr155
gene id: 8090:gpr155
uniprot id: H2MSZ8
names: Subcellular Location Annotation
messages: Membrane

8090:mapk8ip2
gene id: 8090:mapk8ip2
uniprot id: A0A3B3HVJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JIP scaffold family.
messages: Cytoplasm

8090:slc16a3
gene id: 8090:slc16a3
uniprot id: A0A3B3HPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8090:nr1h4
gene id: 8090:nr1h4
uniprot id: H2M6M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8090:LOC101163152
gene id: 8090:LOC101163152
uniprot id: A0A3B3HBS2
names: Similarity
messages: Belongs to the NDRG family.

8090:map3k8
gene id: 8090:map3k8
uniprot id: A0A3B3ILX9
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8090:LOC101173729
gene id: 8090:LOC101173729
uniprot id: H2LJX8
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101162428
gene id: 8090:LOC101162428
uniprot id: G5ELX4
names: Subcellular Location Annotation
messages: Membrane

8090:nek8
gene id: 8090:nek8
uniprot id: H2LHT3
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

8090:cog7
gene id: 8090:cog7
uniprot id: H2LS47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:slc35a1
gene id: 8090:slc35a1
uniprot id: Q8AXU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8090:ldlrad4
gene id: 8090:ldlrad4
uniprot id: A0A3B3HAD7
uniprot id: A0A3P9J9K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8090:c17h7orf25
gene id: 8090:c17h7orf25
uniprot id: H2LVZ8
names: Similarity
messages: Belongs to the UPF0415 family.

8090:LOC101169500
gene id: 8090:LOC101169500
uniprot id: A0A3B3HHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8090:ppp1r9a
gene id: 8090:ppp1r9a
uniprot id: H2LHT1
names: Subcellular Location Annotation
messages: cytoskeleton

8090:LOC101169460
gene id: 8090:LOC101169460
uniprot id: A0A3B3HT89
names: Similarity
messages: Belongs to the CKAP2 family.

8090:cmtm8
gene id: 8090:cmtm8
uniprot id: A0A3B3I109
names: Subcellular Location Annotation
messages: Membrane

8090:pqlc1
gene id: 8090:pqlc1
uniprot id: A0A3B3I6M0
uniprot id: A0A3B3IC47
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101161551
gene id: 8090:LOC101161551
uniprot id: H2M5M5
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8090:LOC101162517
gene id: 8090:LOC101162517
uniprot id: H2LAM7
names: Similarity
messages: Belongs to the BicD family.

8090:bbs5
gene id: 8090:bbs5
uniprot id: H2MRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

8090:LOC100415783
gene id: 8090:LOC100415783
uniprot id: A0A3P9LPA5
uniprot id: Q76B52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8090:med30
gene id: 8090:med30
uniprot id: A0A3B3H907
uniprot id: A0A3P9I8A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8090:LOC101171737
gene id: 8090:LOC101171737
uniprot id: A0A3P9M8S4
uniprot id: H2LYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8090:gpcpd1
gene id: 8090:gpcpd1
uniprot id: A0A3B3HVN8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8090:ndufa6
gene id: 8090:ndufa6
uniprot id: H2MII2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8090:mief1
gene id: 8090:mief1
uniprot id: A0A3B3ICS9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8090:LOC101156324
gene id: 8090:LOC101156324
uniprot id: H2L7V7
names: Subcellular Location Annotation
messages: Membrane

8090:eif2s2
gene id: 8090:eif2s2
uniprot id: H2LEP1
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

8090:inpp5d
gene id: 8090:inpp5d
uniprot id: H2MLD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

8090:hirip3
gene id: 8090:hirip3
uniprot id: H2M6E3
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101168632
gene id: 8090:LOC101168632
uniprot id: A0A3P9MR12
uniprot id: H2LCK4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:ppih
gene id: 8090:ppih
uniprot id: A0A3B3HUQ3
uniprot id: A0A3P9J2X4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8090:papolg
gene id: 8090:papolg
uniprot id: H2L7Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

8090:LOC101158859
gene id: 8090:LOC101158859
uniprot id: H2MD74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

8090:lrp10
gene id: 8090:lrp10
uniprot id: A0A3B3I000
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:mc6ast4
gene id: 8090:mc6ast4
uniprot id: A0A3P9LLS6
uniprot id: Q14TH5
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:c4h19orf70
gene id: 8090:c4h19orf70
uniprot id: A0A3B3H5A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

8090:plbd1
gene id: 8090:plbd1
uniprot id: H2MGZ5
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

8090:nek6
gene id: 8090:nek6
uniprot id: A0A3P9LVT9
uniprot id: H2MD44
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:LOC101170297
gene id: 8090:LOC101170297
uniprot id: H2MBG3
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8090:pik3cb
gene id: 8090:pik3cb
uniprot id: A0A3B3HRG4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8090:nup62
gene id: 8090:nup62
uniprot id: H2MSM1
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

8090:gpr137c
gene id: 8090:gpr137c
uniprot id: H2LG18
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8090:ptcd3
gene id: 8090:ptcd3
uniprot id: H2LY10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

8090:gnrh1
gene id: 8090:gnrh1
uniprot id: Q9DGC8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the GnRH family.
messages: Expressed in the cell bodies of a cluster of neurons in the preoptic region.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.
messages: Teleost species possess three paralogous GnRHs: mdGnRH and cGnRH-II have been identified in tetrapods; sGnRH has no tetrapod ortholog and is thought to be a duplication of cGnRH-II.

8090:LOC101162798
gene id: 8090:LOC101162798
uniprot id: A0A3B3IDS1
names: Similarity
messages: Belongs to the MARCKS family.

8090:abcb3
gene id: 8090:abcb3
uniprot id: Q8UUM0
names: Subcellular Location Annotation
messages: Membrane

8090:mcm7
gene id: 8090:mcm7
uniprot id: H2L4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

8090:rhbg
gene id: 8090:rhbg
uniprot id: Q69D47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cytoplasmic vesicle membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill (By similarity).

8090:rps12
gene id: 8090:rps12
uniprot id: A0A3P9IPC0
uniprot id: H2MPF0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

8090:LOC101169291
gene id: 8090:LOC101169291
uniprot id: H2LTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

8090:LOC101161061
gene id: 8090:LOC101161061
uniprot id: H2MKC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC105357250
gene id: 8090:LOC105357250
uniprot id: A0A3B3HAE2
names: Subcellular Location Annotation
messages: Membrane

8090:nsdhl
gene id: 8090:nsdhl
uniprot id: H2LPN0
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8090:LOC101157526
gene id: 8090:LOC101157526
uniprot id: H2LR84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

8090:LOC100049501
gene id: 8090:LOC100049501
uniprot id: A0A3B3HRQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

8090:itga3
gene id: 8090:itga3
uniprot id: A0A3B3IMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8090:LOC101167930
gene id: 8090:LOC101167930
uniprot id: A0A3B3HDF2
uniprot id: A0A3P9M5W1
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101155710
gene id: 8090:LOC101155710
uniprot id: A0A3P9KXA0
uniprot id: H2MBS7
names: Similarity
messages: Belongs to the DCK/DGK family.

8090:ehd2
gene id: 8090:ehd2
uniprot id: A0A3P9HB06
uniprot id: H2LA80
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8090:LOC101168468
gene id: 8090:LOC101168468
uniprot id: H2L7P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

8090:tmem86a
gene id: 8090:tmem86a
uniprot id: H2MW18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

8090:pmel
gene id: 8090:pmel
uniprot id: H2MJF8
names: Similarity
messages: Belongs to the PMEL/NMB family.

8090:LOC101169697
gene id: 8090:LOC101169697
uniprot id: A0A3B3HGN3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101173458
gene id: 8090:LOC101173458
uniprot id: H2LZY4
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8090:psma5
gene id: 8090:psma5
uniprot id: A0A3P9HLY4
uniprot id: H2MMN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8090:flt1
gene id: 8090:flt1
uniprot id: H2LXU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:uba1
gene id: 8090:uba1
uniprot id: H2LXD0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

8090:gsx1
gene id: 8090:gsx1
uniprot id: O93290
names: Subcellular Location Annotation
messages: Nucleus

8090:srpx2
gene id: 8090:srpx2
uniprot id: H2L706
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:hck
gene id: 8090:hck
uniprot id: A0A3B3IGN4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8090:ints10
gene id: 8090:ints10
uniprot id: A0A3B3HLL8
uniprot id: A0A3B3I7N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

8090:pelo
gene id: 8090:pelo
uniprot id: A0A3B3IH31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.
messages: Cytoplasm

8090:LOC101167681
gene id: 8090:LOC101167681
uniprot id: A0A3P9IXA8
names: Similarity
messages: Belongs to the syntaxin family.

8090:LOC101167978
gene id: 8090:LOC101167978
uniprot id: H2L781
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

8090:LOC101157515
gene id: 8090:LOC101157515
uniprot id: H2MDV3
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

8090:fgf6
gene id: 8090:fgf6
uniprot id: A0A3P9IS55
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8090:ccnf
gene id: 8090:ccnf
uniprot id: H2LVX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.
messages: Nucleus
messages: centriole
messages: perinuclear region

8090:LOC101169283
gene id: 8090:LOC101169283
uniprot id: H2MMM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101169368
gene id: 8090:LOC101169368
uniprot id: H2M389
names: Similarity
messages: Belongs to the ARTD/PARP family.

8090:kdm3b
gene id: 8090:kdm3b
uniprot id: A0A3B3HFL7
uniprot id: H2LLD0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

8090:tmem255a
gene id: 8090:tmem255a
uniprot id: A0A3B3HU98
uniprot id: A0A3P9HW54
uniprot id: A0A3P9HWD8
uniprot id: H2L655
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

8090:cmc4
gene id: 8090:cmc4
uniprot id: A0A3B3IP40
uniprot id: A0A3P9JJD1
names: Similarity
messages: Belongs to the CMC4 family.

8090:LOC101157518
gene id: 8090:LOC101157518
uniprot id: H2LNC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

8090:c1h6orf120
gene id: 8090:c1h6orf120
uniprot id: H2L340
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

8090:ncln
gene id: 8090:ncln
uniprot id: A0A3P9KSE5
uniprot id: H2MSV6
names: Similarity
messages: Belongs to the nicastrin family.

8090:adk
gene id: 8090:adk
uniprot id: A0A3B3IB70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

8090:isg12(1)
gene id: 8090:isg12(1)
uniprot id: Q6IEB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

8090:LOC101164400
gene id: 8090:LOC101164400
uniprot id: A0A3B3HPQ9
uniprot id: A0A3P9MAB2
uniprot id: H2MF83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8090:suox
gene id: 8090:suox
uniprot id: A0A3B3H494
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.
messages: Mitochondrion intermembrane space

8090:kif2a
gene id: 8090:kif2a
uniprot id: A0A3B3HI65
uniprot id: A0A3P9M3X5
uniprot id: A0A3P9M485
uniprot id: H2LZF0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:LOC101170375
gene id: 8090:LOC101170375
uniprot id: A0A3B3HHL9
names: Similarity
messages: Belongs to the TGF-beta family.

8090:wdr83os
gene id: 8090:wdr83os
uniprot id: A0A3B3I3J5
uniprot id: A0A3P9KDQ4
names: Similarity
messages: Belongs to the Asterix family.

8090:LOC101164612
gene id: 8090:LOC101164612
uniprot id: H2MC59
names: Similarity
messages: Belongs to the sorting nexin family.

8090:LOC101174433
gene id: 8090:LOC101174433
uniprot id: A0A3B3H6L5
uniprot id: H2LLZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8090:LOC101172075
gene id: 8090:LOC101172075
uniprot id: H2LWK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8090:ncbp2
gene id: 8090:ncbp2
uniprot id: A0A3P9KBU8
uniprot id: H2M6J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

8090:LOC101168854
gene id: 8090:LOC101168854
uniprot id: A0A3B3HKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum
messages: flagellum axoneme

8090:LOC101157174
gene id: 8090:LOC101157174
uniprot id: H2LZT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:casp8
gene id: 8090:casp8
uniprot id: Q56VC9
names: Similarity
messages: Belongs to the peptidase C14A family.

8090:LOC101157692
gene id: 8090:LOC101157692
uniprot id: H2M1L0
names: Similarity
messages: Belongs to the PP2C family.

8090:ftsj3
gene id: 8090:ftsj3
uniprot id: H2LN08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

8090:LOC101155336
gene id: 8090:LOC101155336
uniprot id: H2L4I7
names: Subcellular Location Annotation
messages: Membrane

8090:cnmd
gene id: 8090:cnmd
uniprot id: A4ZWB5
names: Similarity
messages: Belongs to the chondromodulin-1 family.

8090:LOC101165325
gene id: 8090:LOC101165325
uniprot id: A0A3B3HLR6
uniprot id: A0A3B3HV57
uniprot id: H2M0R1
names: Similarity
messages: Belongs to the MAP7 family.

8090:chmp2b
gene id: 8090:chmp2b
uniprot id: A0A3P9LPY4
uniprot id: H2MME5
names: Similarity
messages: Belongs to the SNF7 family.

8090:LOC101161969
gene id: 8090:LOC101161969
uniprot id: A0A3B3I0Q3
uniprot id: A0A3P9HIV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8090:fam114a1
gene id: 8090:fam114a1
uniprot id: H2LLB5
names: Similarity
messages: Belongs to the FAM114 family.

8090:egfr
gene id: 8090:egfr
uniprot id: H2MTN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8090:slc25a36
gene id: 8090:slc25a36
uniprot id: A0A3P9J9W4
uniprot id: H2MLJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:LOC101155013
gene id: 8090:LOC101155013
uniprot id: H2L6K2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8090:ccnc
gene id: 8090:ccnc
uniprot id: A0A3B3HNI4
uniprot id: A0A3P9JS69
names: Similarity
messages: Belongs to the cyclin family.

8090:map1lc3c
gene id: 8090:map1lc3c
uniprot id: H2N0H4
names: Similarity
messages: Belongs to the ATG8 family.

8090:LOC101165775
gene id: 8090:LOC101165775
uniprot id: H2MUQ8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8090:slc1a2
gene id: 8090:slc1a2
uniprot id: A0A3B3HHH0
uniprot id: H2M9C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8090:serpind1
gene id: 8090:serpind1
uniprot id: H2LA83
names: Similarity
messages: Belongs to the serpin family.

8090:lsm4
gene id: 8090:lsm4
uniprot id: H2LWP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

8090:LOC101167495
gene id: 8090:LOC101167495
uniprot id: H2LDM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

8090:lhcgr
gene id: 8090:lhcgr
uniprot id: D4QE77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

8090:LOC101172166
gene id: 8090:LOC101172166
uniprot id: A0A3P9LFU2
uniprot id: H2LUP8
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8090:rab32
gene id: 8090:rab32
uniprot id: H2MGM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8090:cenpi
gene id: 8090:cenpi
uniprot id: H2L7I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

8090:tm7sf2
gene id: 8090:tm7sf2
uniprot id: A0A3B3HDU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

8090:vps35l
gene id: 8090:vps35l
uniprot id: H2N1D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

8090:znf598
gene id: 8090:znf598
uniprot id: H2MCS1
names: Similarity
messages: Belongs to the ZNF598/HEL2 family.

8090:rsl24d1
gene id: 8090:rsl24d1
uniprot id: H2LL67
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

8090:LOC101161896
gene id: 8090:LOC101161896
uniprot id: A0A3B3H2K5
uniprot id: A0A3P9I9I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8090:LOC101164413
gene id: 8090:LOC101164413
uniprot id: A0A3B3IHR7
uniprot id: A0A3P9KA80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8090:cap2
gene id: 8090:cap2
uniprot id: A0A3B3HIL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

8090:c3-1
gene id: 8090:c3-1
uniprot id: Q9IBH1
names: Subcellular Location Annotation
messages: Secreted

8090:LOC101160342
gene id: 8090:LOC101160342
uniprot id: A0A3P9HLC0
uniprot id: H2LT37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8090:LOC101163512
gene id: 8090:LOC101163512
uniprot id: H2L5F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8090:c24h12orf57
gene id: 8090:c24h12orf57
uniprot id: A0A3P9JAT8
uniprot id: H2M6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

8090:LOC100125518
gene id: 8090:LOC100125518
uniprot id: H2M746
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

8090:LOC101161999
gene id: 8090:LOC101161999
uniprot id: H2M8Z7
names: Subcellular Location Annotation
messages: Membrane

8090:mtf2
gene id: 8090:mtf2
uniprot id: H2LKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

8090:LOC101160424
gene id: 8090:LOC101160424
uniprot id: H2MAS0
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101157000
gene id: 8090:LOC101157000
uniprot id: H2L7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

8090:LOC101158934
gene id: 8090:LOC101158934
uniprot id: A0A3B3H544
uniprot id: A0A3B3I2S8
uniprot id: A0A3P9HRQ0
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8090:tonsl
gene id: 8090:tonsl
uniprot id: H2MIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tonsoku family.
messages: Chromosome

8090:wisp1
gene id: 8090:wisp1
uniprot id: H2LEJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:pex7
gene id: 8090:pex7
uniprot id: H2LZP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

8090:nop2
gene id: 8090:nop2
uniprot id: H2M9L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

8090:aars
gene id: 8090:aars
uniprot id: H2ME04
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

8090:LOC101160739
gene id: 8090:LOC101160739
uniprot id: H2LFK3
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

8090:nanos3
gene id: 8090:nanos3
uniprot id: A0A3P9K737
uniprot id: A7XBY3
names: Similarity
messages: Belongs to the nanos family.

8090:ak5
gene id: 8090:ak5
uniprot id: H2LDW5
names: Similarity
messages: Belongs to the adenylate kinase family.

8090:LOC101161427
gene id: 8090:LOC101161427
uniprot id: A0A3B3HU72
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

8090:mllt11
gene id: 8090:mllt11
uniprot id: A0A3B3I2V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

8090:LOC101166640
gene id: 8090:LOC101166640
uniprot id: H2M3I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

8090:LOC101173533
gene id: 8090:LOC101173533
uniprot id: H2LFL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:LOC101157658
gene id: 8090:LOC101157658
uniprot id: A0A3B3HBZ7
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101170232
gene id: 8090:LOC101170232
uniprot id: A0A3B3HIS8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8090:umps
gene id: 8090:umps
uniprot id: H2N1Z7
names: Similarity
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

8090:LOC101173349
gene id: 8090:LOC101173349
uniprot id: A0A3B3HKF4
uniprot id: A0A3P9I9T9
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8090:prdm2
gene id: 8090:prdm2
uniprot id: H2LG85
names: Subcellular Location Annotation
messages: Nucleus

8090:ndufs2
gene id: 8090:ndufs2
uniprot id: A0A3P9HZT4
uniprot id: H2M6U2
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

8090:LOC101174784
gene id: 8090:LOC101174784
uniprot id: A0A3B3I2H8
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101165591
gene id: 8090:LOC101165591
uniprot id: A0A3B3IHZ8
uniprot id: A0A3P9H9G1
uniprot id: A0A3P9LSZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8090:rce1
gene id: 8090:rce1
uniprot id: A0A3B3HLD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:kcns2
gene id: 8090:kcns2
uniprot id: A0A3P9LKI4
uniprot id: H2LC60
names: Subcellular Location Annotation
messages: Membrane

8090:lnpk
gene id: 8090:lnpk
uniprot id: H2MT40
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

8090:med20
gene id: 8090:med20
uniprot id: H2L3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8090:yeats2
gene id: 8090:yeats2
uniprot id: A0A3B3IP02
names: Subcellular Location Annotation
messages: Nucleus

8090:selenoo
gene id: 8090:selenoo
uniprot id: H2MNV7
names: Similarity
messages: Belongs to the SELO family.

8090:LOC101156763
gene id: 8090:LOC101156763
uniprot id: H2LHQ8
names: Similarity
messages: Belongs to the phospholipase D family.

8090:ccdc58
gene id: 8090:ccdc58
uniprot id: A0A3B3HTU7
names: Similarity
messages: Belongs to the MIX23 family.

8090:LOC101163577
gene id: 8090:LOC101163577
uniprot id: H2M0C4
names: Similarity
messages: Belongs to the FAM20 family.

8090:LOC101156223
gene id: 8090:LOC101156223
uniprot id: A0A3B3I6L2
names: Subcellular Location Annotation
messages: Membrane

8090:smoc2
gene id: 8090:smoc2
uniprot id: A0A3B3H774
uniprot id: A0A3P9IIJ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:fdps
gene id: 8090:fdps
uniprot id: H2M2F2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8090:ca14
gene id: 8090:ca14
uniprot id: H2M392
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

8090:LOC101155299
gene id: 8090:LOC101155299
uniprot id: A0A3P9H9F9
uniprot id: H2M3Y1
names: Similarity
messages: Belongs to the uridine kinase family.

8090:ppm1a
gene id: 8090:ppm1a
uniprot id: A0A3B3HVK2
uniprot id: H2MM16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8090:mrpl19
gene id: 8090:mrpl19
uniprot id: H2MCN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

8090:LOC101162842
gene id: 8090:LOC101162842
uniprot id: A0A3B3IDM4
names: Subcellular Location Annotation
messages: Membrane

8090:eif3k
gene id: 8090:eif3k
uniprot id: A0A3P9LF36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

8090:LOC101157894
gene id: 8090:LOC101157894
uniprot id: A0A3B3HNA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. FIT1 subfamily.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the formation of lipid droplets (LDs), which are storage organelles at the center of lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol.
messages: Membrane

8090:tph2
gene id: 8090:tph2
uniprot id: H2L3G1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8090:LOC101166465
gene id: 8090:LOC101166465
uniprot id: H2MC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

8090:p2ry1
gene id: 8090:p2ry1
uniprot id: H2LMX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101171932
gene id: 8090:LOC101171932
uniprot id: H2M6E9
names: Similarity
messages: Belongs to the folate receptor family.

8090:LOC101173950
gene id: 8090:LOC101173950
uniprot id: A0A3P9I5Z1
uniprot id: H2L9Y4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101165729
gene id: 8090:LOC101165729
uniprot id: H2LAG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:acaa2
gene id: 8090:acaa2
uniprot id: A0A3P9K8S4
uniprot id: H2LBC5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

8090:pou2f1
gene id: 8090:pou2f1
uniprot id: A0A3B3IA89
uniprot id: H2MBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

8090:uba5
gene id: 8090:uba5
uniprot id: A0A3B3IMU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Golgi apparatus

8090:LOC101174249
gene id: 8090:LOC101174249
uniprot id: A0A3B3H272
uniprot id: A0A3P9KR78
names: Similarity
messages: Belongs to the BZW family.

8090:nelfe
gene id: 8090:nelfe
uniprot id: H2L983
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

8090:dhrs7
gene id: 8090:dhrs7
uniprot id: H2MM26
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:amh
gene id: 8090:amh
uniprot id: Q1XHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8090:LOC101165857
gene id: 8090:LOC101165857
uniprot id: A0A3B3H754
uniprot id: H2MD06
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8090:bloc1s6
gene id: 8090:bloc1s6
uniprot id: H2LAZ9
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

8090:lingo1
gene id: 8090:lingo1
uniprot id: A0A3P9JEJ1
names: Subcellular Location Annotation
messages: Membrane

8090:slc35b2
gene id: 8090:slc35b2
uniprot id: A0A3B3HRR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

8090:LOC101163742
gene id: 8090:LOC101163742
uniprot id: A0A3B3HPB9
uniprot id: A0A3B3IMI2
uniprot id: A0A3P9JXT6
uniprot id: A0A3P9LLF2
uniprot id: A0A3P9LLG7
uniprot id: H2LRX7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

8090:coq8a
gene id: 8090:coq8a
uniprot id: A0A3B3IE97
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8090:LOC101158278
gene id: 8090:LOC101158278
uniprot id: H2M8A5
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

8090:hsf1
gene id: 8090:hsf1
uniprot id: A0A3B3I7F6
uniprot id: A0A3B3IMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

8090:mst1r
gene id: 8090:mst1r
uniprot id: A0A3B3HT99
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101165557
gene id: 8090:LOC101165557
uniprot id: A0A3B3I4A1
names: Similarity
messages: Belongs to the GW182 family.

8090:LOC101166169
gene id: 8090:LOC101166169
uniprot id: H2LC40
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

8090:elac2
gene id: 8090:elac2
uniprot id: H2L621
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Z family.
messages: mitochondrion nucleoid

8090:xpo6
gene id: 8090:xpo6
uniprot id: A0A3B3H2N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

8090:fam173a
gene id: 8090:fam173a
uniprot id: A0A3B3ICX1
uniprot id: A0A3P9KXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

8090:LOC105354916
gene id: 8090:LOC105354916
uniprot id: A0A3B3I7Q8
names: Similarity
messages: Belongs to the UPF0461 family.

8090:vdr
gene id: 8090:vdr
uniprot id: B2CCA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8090:klc2
gene id: 8090:klc2
uniprot id: H2LVS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8090:LOC101160945
gene id: 8090:LOC101160945
uniprot id: H2MLB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8090:gapdh
gene id: 8090:gapdh
uniprot id: A0A3P9LTM2
uniprot id: H2M9V7
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

8090:olgc6
gene id: 8090:olgc6
uniprot id: O42129
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8090:thnsl1
gene id: 8090:thnsl1
uniprot id: H2MCR1
names: Similarity
messages: Belongs to the threonine synthase family.

8090:LOC101164740
gene id: 8090:LOC101164740
uniprot id: H2LU89
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:LOC101158730
gene id: 8090:LOC101158730
uniprot id: A0A3B3HBE4
uniprot id: A0A3B3IFM2
names: Similarity
messages: Belongs to the MAGUK family.

8090:cog6
gene id: 8090:cog6
uniprot id: H2LD60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

8090:kcnb2
gene id: 8090:kcnb2
uniprot id: H2LVC0
names: Subcellular Location Annotation
messages: Membrane
messages: Perikaryon
messages: dendrite

8090:urod
gene id: 8090:urod
uniprot id: H2MBG4
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

8090:LOC101157971
gene id: 8090:LOC101157971
uniprot id: A0A3B3HP52
uniprot id: A0A3P9H429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8090:dbx1
gene id: 8090:dbx1
uniprot id: A0A3B3IAG2
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101160014
gene id: 8090:LOC101160014
uniprot id: H2LTT5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8090:LOC101170557
gene id: 8090:LOC101170557
uniprot id: A0A3B3I8M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8090:ivd
gene id: 8090:ivd
uniprot id: H2ML13
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8090:prdm14
gene id: 8090:prdm14
uniprot id: H2LVN9
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101164596
gene id: 8090:LOC101164596
uniprot id: A0A3B3HA12
uniprot id: A0A3B3HB32
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

8090:map3k9
gene id: 8090:map3k9
uniprot id: H2M0D0
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

8090:trim2
gene id: 8090:trim2
uniprot id: H2LWS3
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8090:LOC101167596
gene id: 8090:LOC101167596
uniprot id: A0A3B3HIC0
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101157770
gene id: 8090:LOC101157770
uniprot id: H2LBH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:tmem258
gene id: 8090:tmem258
uniprot id: A0A3B3HYE8
uniprot id: A0A3P9KHB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8090:aldh9a1
gene id: 8090:aldh9a1
uniprot id: Q19A30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Constitutively expressed in all organs tested: brain, eye, gill, GI, heart, liver, kidney, muscle, skin, testis and ovary.
messages: Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency.
messages: Homotetramer.
messages: cytosol

8090:LOC101165489
gene id: 8090:LOC101165489
uniprot id: H2LPP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8090:LOC101160555
gene id: 8090:LOC101160555
uniprot id: H2LY94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8090:gsc
gene id: 8090:gsc
uniprot id: A0A3B3HKR8
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101166704
gene id: 8090:LOC101166704
uniprot id: H2MB62
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

8090:LOC101156386
gene id: 8090:LOC101156386
uniprot id: H2LDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

8090:echs1
gene id: 8090:echs1
uniprot id: A0A3P9LM63
uniprot id: H2LZD1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8090:LOC101167707
gene id: 8090:LOC101167707
uniprot id: H2L764
names: Similarity
messages: Belongs to the intermediate filament family.

8090:LOC101159080
gene id: 8090:LOC101159080
uniprot id: H2MVR8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:snx17
gene id: 8090:snx17
uniprot id: A0A3B3HBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8090:LOC101167890
gene id: 8090:LOC101167890
uniprot id: H2LE97
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101168224
gene id: 8090:LOC101168224
uniprot id: A0A3B3HWG7
uniprot id: A0A3B3ID82
names: Similarity
messages: Belongs to the peptidase S9A family.

8090:syt1
gene id: 8090:syt1
uniprot id: H2MP01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

8090:cdk5rap1
gene id: 8090:cdk5rap1
uniprot id: H2M7J1
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

8090:pdp1
gene id: 8090:pdp1
uniprot id: H2LYA8
names: Similarity
messages: Belongs to the PP2C family.

8090:cyp11a
gene id: 8090:cyp11a
uniprot id: B3IWI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

8090:LOC101159423
gene id: 8090:LOC101159423
uniprot id: H2MCZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC101167108
gene id: 8090:LOC101167108
uniprot id: H2LYF8
names: Similarity
messages: Belongs to the neuritin family.

8090:odr4
gene id: 8090:odr4
uniprot id: H2MEZ3
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

8090:psmb1
gene id: 8090:psmb1
uniprot id: A0A3P9IQU2
uniprot id: H2M528
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8090:LOC101169439
gene id: 8090:LOC101169439
uniprot id: H2L438
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:LOC101174429
gene id: 8090:LOC101174429
uniprot id: H2M607
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

8090:a-sdf1a
gene id: 8090:a-sdf1a
uniprot id: B3KYI4
names: Similarity
messages: Belongs to the intercrine alpha (chemokine CxC) family.

8090:LOC101159349
gene id: 8090:LOC101159349
uniprot id: H2LD25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

8090:tysnd1
gene id: 8090:tysnd1
uniprot id: H2LR26
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

8090:st3gal2
gene id: 8090:st3gal2
uniprot id: Q5ND65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:cwf19l1
gene id: 8090:cwf19l1
uniprot id: H2MS92
names: Similarity
messages: Belongs to the CWF19 family.

8090:setd7
gene id: 8090:setd7
uniprot id: H2M4L5
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8090:sh2b3
gene id: 8090:sh2b3
uniprot id: H2LES0
names: Similarity
messages: Belongs to the SH2B adapter family.

8090:LOC100302438
gene id: 8090:LOC100302438
uniprot id: C5HIF5
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:oat
gene id: 8090:oat
uniprot id: A0A3P9K9K3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

8090:cacnb2
gene id: 8090:cacnb2
uniprot id: A0A3B3HQ17
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

8090:armc9
gene id: 8090:armc9
uniprot id: A0A3B3H7H9
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cilium basal body

8090:anp32b
gene id: 8090:anp32b
uniprot id: H2LS25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

8090:grm5
gene id: 8090:grm5
uniprot id: A0A3B3IBI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8090:LOC101170717
gene id: 8090:LOC101170717
uniprot id: A0A3B3HQF4
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8090:LOC101174485
gene id: 8090:LOC101174485
uniprot id: H2M4Z7
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8090:riok1
gene id: 8090:riok1
uniprot id: H2LW37
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

8090:nup93
gene id: 8090:nup93
uniprot id: A0A3P9M6N4
uniprot id: H2MLE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

8090:pomk
gene id: 8090:pomk
uniprot id: A0A3B3HNC6
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

8090:LOC101171430
gene id: 8090:LOC101171430
uniprot id: H2LZF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus
messages: telomere

8090:LOC101160113
gene id: 8090:LOC101160113
uniprot id: A0A3B3HLH6
names: Subcellular Location Annotation
messages: cytoskeleton

8090:LOC101159348
gene id: 8090:LOC101159348
uniprot id: A0A3B3HCS6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

8090:LOC101163727
gene id: 8090:LOC101163727
uniprot id: H2LHR2
uniprot id: H2LHR4
names: Subcellular Location Annotation
messages: extracellular space

8090:nfkb2
gene id: 8090:nfkb2
uniprot id: H2LCN6
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101174333
gene id: 8090:LOC101174333
uniprot id: H2N2G9
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

8090:yme1l1
gene id: 8090:yme1l1
uniprot id: H2MBY0
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

8090:LOC101155143
gene id: 8090:LOC101155143
uniprot id: A0A3B3I108
names: Subcellular Location Annotation
messages: Membrane
messages: Perikaryon
messages: dendrite

8090:brk1
gene id: 8090:brk1
uniprot id: A0A3P9LJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

8090:lypla2
gene id: 8090:lypla2
uniprot id: H2LTE2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

8090:plekha8
gene id: 8090:plekha8
uniprot id: A0A3B3ILZ5
names: Subcellular Location Annotation
messages: trans-Golgi network membrane

8090:LOC101167832
gene id: 8090:LOC101167832
uniprot id: H2MNF4
names: Similarity
messages: Belongs to the sulfatase family.

8090:snf8
gene id: 8090:snf8
uniprot id: A0A3P9IIB6
uniprot id: H2MAL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

8090:LOC101165997
gene id: 8090:LOC101165997
uniprot id: H2LWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

8090:pllp
gene id: 8090:pllp
uniprot id: A0A3B3H4E7
names: Subcellular Location Annotation
messages: Membrane

8090:c9h12orf43
gene id: 8090:c9h12orf43
uniprot id: H2MIH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

8090:LOC101160554
gene id: 8090:LOC101160554
uniprot id: A0A3B3HGR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101159230
gene id: 8090:LOC101159230
uniprot id: A0A3B3H6Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

8090:LOC101156841
gene id: 8090:LOC101156841
uniprot id: A0A3B3HKQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

8090:LOC101163254
gene id: 8090:LOC101163254
uniprot id: H2LZK2
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.

8090:LOC101161729
gene id: 8090:LOC101161729
uniprot id: A0A3P9KRJ6
uniprot id: H2MA76
names: Similarity
messages: Belongs to the Rho GDI family.

8090:LOC101172355
gene id: 8090:LOC101172355
uniprot id: H2LEM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

8090:LOC101161391
gene id: 8090:LOC101161391
uniprot id: A0A3P9HE73
uniprot id: H2LUB1
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101161023
gene id: 8090:LOC101161023
uniprot id: H2MNH5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:tram1
gene id: 8090:tram1
uniprot id: A0A3P9I5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

8090:ccdc181
gene id: 8090:ccdc181
uniprot id: H2LLY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton

8090:LOC105353973
gene id: 8090:LOC105353973
uniprot id: H2MCK3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8090:mrpl13
gene id: 8090:mrpl13
uniprot id: H2LIL9
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

8090:nt5dc2
gene id: 8090:nt5dc2
uniprot id: H2MG38
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

8090:LOC101171082
gene id: 8090:LOC101171082
uniprot id: A0A3B3ILE7
uniprot id: A0A3P9J806
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:LOC101170613
gene id: 8090:LOC101170613
uniprot id: A0A3B3HJU8
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

8090:txndc5
gene id: 8090:txndc5
uniprot id: H2LQ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8090:ifih1
gene id: 8090:ifih1
uniprot id: H2MQX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

8090:zc3h12d
gene id: 8090:zc3h12d
uniprot id: H2MKC8
names: Similarity
messages: Belongs to the ZC3H12 family.

8090:mcu
gene id: 8090:mcu
uniprot id: A0A3P9MFN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

8090:LOC101162537
gene id: 8090:LOC101162537
uniprot id: A0A3P9HF54
uniprot id: H2M044
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

8090:LOC101162453
gene id: 8090:LOC101162453
uniprot id: H2LY31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

8090:hgfac
gene id: 8090:hgfac
uniprot id: H2LNH0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8090:zdhhc13
gene id: 8090:zdhhc13
uniprot id: H2L574
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:LOC101174549
gene id: 8090:LOC101174549
uniprot id: H2MJ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

8090:mat2b
gene id: 8090:mat2b
uniprot id: H2MEL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

8090:nat9
gene id: 8090:nat9
uniprot id: A0A3B3IHF5
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

8090:LOC101165421
gene id: 8090:LOC101165421
uniprot id: A0A3B3HZ37
uniprot id: A0A3P9IM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8090:ccnb3
gene id: 8090:ccnb3
uniprot id: A0A3B3H8P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8090:LOC101161208
gene id: 8090:LOC101161208
uniprot id: H2MCE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8090:LOC101165021
gene id: 8090:LOC101165021
uniprot id: H2M421
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:golt1a
gene id: 8090:golt1a
uniprot id: A0A3B3IF16
uniprot id: A0A3P9LRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

8090:dolk
gene id: 8090:dolk
uniprot id: A0A3B3IDV5
names: Similarity
messages: Belongs to the polyprenol kinase family.

8090:rab4a
gene id: 8090:rab4a
uniprot id: A0A3B3IIC4
uniprot id: A0A3P9LQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

8090:LOC101174244
gene id: 8090:LOC101174244
uniprot id: A0A3P9L2T2
uniprot id: H2L7H3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8090:KEF90 p02
gene id: 8090:KEF90_p02
uniprot id: Q8HLW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

8090:LOC101160266
gene id: 8090:LOC101160266
uniprot id: H2MIE3
names: Subcellular Location Annotation
messages: Membrane

8090:nsg2
gene id: 8090:nsg2
uniprot id: A0A3B3H8S2
names: Similarity
messages: Belongs to the NSG family.

8090:LOC101169974
gene id: 8090:LOC101169974
uniprot id: H2M051
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8090:LOC101156116
gene id: 8090:LOC101156116
uniprot id: H2M279
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101175113
gene id: 8090:LOC101175113
uniprot id: A0A3B3H3D3
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8090:LOC101166139
gene id: 8090:LOC101166139
uniprot id: A0A3B3IGE8
uniprot id: A0A3P9JUH6
names: Similarity
messages: Belongs to the FAM219 family.

8090:LOC101170803
gene id: 8090:LOC101170803
uniprot id: H2MAS4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101159054
gene id: 8090:LOC101159054
uniprot id: H2MIV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

8090:hspa5
gene id: 8090:hspa5
uniprot id: A0A3P9MLW1
uniprot id: G5ELX5
uniprot id: H2LRF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

8090:tsr2
gene id: 8090:tsr2
uniprot id: A0A3B3IHG3
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

8090:LOC101156309
gene id: 8090:LOC101156309
uniprot id: A0A3B3HGM6
uniprot id: A0A3P9ILF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

8090:LOC101160952
gene id: 8090:LOC101160952
uniprot id: A0A3B3HS63
uniprot id: A0A3P9IHW6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8090:crat
gene id: 8090:crat
uniprot id: H2ME99
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8090:zdhhc22
gene id: 8090:zdhhc22
uniprot id: H2MNL7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:LOC101162136
gene id: 8090:LOC101162136
uniprot id: A0A3B3HCB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

8090:fshb
gene id: 8090:fshb
uniprot id: A0A3P9JWD7
uniprot id: F8WKS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8090:LOC101158446
gene id: 8090:LOC101158446
uniprot id: A0A3B3H3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:kif26b
gene id: 8090:kif26b
uniprot id: H2M6Q9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:LOC101160696
gene id: 8090:LOC101160696
uniprot id: A0A3B3HIJ0
names: Similarity
messages: Belongs to the FAM124 family.

8090:ggnbp2
gene id: 8090:ggnbp2
uniprot id: H2M6X0
names: Function
messages: May be involved in spermatogenesis.

8090:trmu
gene id: 8090:trmu
uniprot id: H2MXP7
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

8090:cryaa
gene id: 8090:cryaa
uniprot id: A0A3P9KXC7
uniprot id: H2N2D4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8090:neto2
gene id: 8090:neto2
uniprot id: A0A3B3I456
uniprot id: A0A3P9I357
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:galnt18
gene id: 8090:galnt18
uniprot id: H2LSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101158210
gene id: 8090:LOC101158210
uniprot id: A0A3B3I041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8090:gsta4
gene id: 8090:gsta4
uniprot id: H2M151
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

8090:LOC101159916
gene id: 8090:LOC101159916
uniprot id: H2LJP5
names: Subcellular Location Annotation
messages: Membrane

8090:efna1
gene id: 8090:efna1
uniprot id: H2M1M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101161045
gene id: 8090:LOC101161045
uniprot id: H2MBK4
names: Subcellular Location Annotation
messages: Nucleus

8090:itprip
gene id: 8090:itprip
uniprot id: H2LP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

8090:LOC101167975
gene id: 8090:LOC101167975
uniprot id: A0A3P9HMI5
uniprot id: B6F103
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:ap3s1
gene id: 8090:ap3s1
uniprot id: A0A3P9K3Q2
uniprot id: H2LE72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

8090:LOC101170368
gene id: 8090:LOC101170368
uniprot id: A0A3B3I0V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

8090:LOC101167868
gene id: 8090:LOC101167868
uniprot id: A0A3B3HJB0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:ttc3
gene id: 8090:ttc3
uniprot id: A0A3B3I8G2
names: Subcellular Location Annotation
messages: Cytoplasm

8090:tas1r3
gene id: 8090:tas1r3
uniprot id: Q2MHK2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101167225
gene id: 8090:LOC101167225
uniprot id: H2LVT6
names: Subcellular Location Annotation
messages: Membrane

8090:plrg1
gene id: 8090:plrg1
uniprot id: H2LWD5
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

8090:kat7
gene id: 8090:kat7
uniprot id: A0A3B3I2R3
uniprot id: A0A3P9LIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8090:igf2bp3
gene id: 8090:igf2bp3
uniprot id: H2LIU6
names: Similarity
messages: Belongs to the RRM IMP/VICKZ family.

8090:rorb
gene id: 8090:rorb
uniprot id: A0A3B3H2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8090:LOC101173824
gene id: 8090:LOC101173824
uniprot id: H2MLJ8
names: Similarity
messages: Belongs to the YY transcription factor family.

8090:purb
gene id: 8090:purb
uniprot id: H2L5F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

8090:snx25
gene id: 8090:snx25
uniprot id: H2LYG9
names: Similarity
messages: Belongs to the sorting nexin family.

8090:LOC110013316
gene id: 8090:LOC110013316
uniprot id: A0A3B3HQI4
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:ube2k
gene id: 8090:ube2k
uniprot id: A0A3B3I6K1
uniprot id: A0A3P9IUJ2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:LOC101168736
gene id: 8090:LOC101168736
uniprot id: H2MIP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:prkd2
gene id: 8090:prkd2
uniprot id: A0A3B3H6M1
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

8090:LOC101166992
gene id: 8090:LOC101166992
uniprot id: A0A3B3HY33
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

8090:sfrp1
gene id: 8090:sfrp1
uniprot id: A0A3P9MKK9
uniprot id: Q6GZK1
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101169590
gene id: 8090:LOC101169590
uniprot id: A0A3B3IHS8
names: Subcellular Location Annotation
messages: Membrane

8090:ccdc107
gene id: 8090:ccdc107
uniprot id: A0A3B3HQN5
names: Similarity
messages: Belongs to the ric-3 family.

8090:LOC105354400
gene id: 8090:LOC105354400
uniprot id: H2LY56
names: Similarity
messages: Belongs to the FAM83 family.

8090:LOC101165434
gene id: 8090:LOC101165434
uniprot id: H2MV95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8090:LOC101174853
gene id: 8090:LOC101174853
uniprot id: H2MIU2
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101161926
gene id: 8090:LOC101161926
uniprot id: H2LFH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8090:LOC101160587
gene id: 8090:LOC101160587
uniprot id: H2LK64
names: Similarity
messages: Belongs to the DIPK family.

8090:mterf3
gene id: 8090:mterf3
uniprot id: H2MBH7
names: Similarity
messages: Belongs to the mTERF family.

8090:LOC100533498
gene id: 8090:LOC100533498
uniprot id: A0A3P9LNU3
uniprot id: E3WET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8090:LOC101166934
gene id: 8090:LOC101166934
uniprot id: H2LJH5
names: Subcellular Location Annotation
messages: Membrane

8090:sirt3
gene id: 8090:sirt3
uniprot id: A0A3B3IP03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.

8090:sept10
gene id: 8090:sept10
uniprot id: A0A3P9IUW2
uniprot id: H2MMI9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

8090:LOC101172208
gene id: 8090:LOC101172208
uniprot id: A0A3B3H3X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:vti1a
gene id: 8090:vti1a
uniprot id: A0A3B3H6F6
uniprot id: A0A3B3ICC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

8090:slc35e3
gene id: 8090:slc35e3
uniprot id: A0A3P9HBJ5
uniprot id: H2MRW6
names: Subcellular Location Annotation
messages: Membrane

8090:ercc5
gene id: 8090:ercc5
uniprot id: H2LJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

8090:ssr1
gene id: 8090:ssr1
uniprot id: A0A3P9M5T6
uniprot id: A0A3P9M5Z4
uniprot id: H2LDF6
uniprot id: H2LDF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

8090:LOC101157618
gene id: 8090:LOC101157618
uniprot id: H2MM85
names: Subcellular Location Annotation
messages: Membrane

8090:cpt2
gene id: 8090:cpt2
uniprot id: H2MEX2
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8090:bcap29
gene id: 8090:bcap29
uniprot id: H2LWC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

8090:adamts18
gene id: 8090:adamts18
uniprot id: A0A3B3HUE1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8090:glis3
gene id: 8090:glis3
uniprot id: C6KXM3
uniprot id: C6KXM4
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8090:nkap
gene id: 8090:nkap
uniprot id: H2L633
names: Similarity
messages: Belongs to the NKAP family.

8090:LOC101173412
gene id: 8090:LOC101173412
uniprot id: A0A3P9HC50
uniprot id: H2M2C2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8090:atad1
gene id: 8090:atad1
uniprot id: A0A3B3IAR4
uniprot id: A0A3P9J4H8
names: Similarity
messages: Belongs to the AAA ATPase family.

8090:dlx6
gene id: 8090:dlx6
uniprot id: A0A3P9K2H4
uniprot id: H2LI86
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101158047
gene id: 8090:LOC101158047
uniprot id: H2LGB5
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:prkx
gene id: 8090:prkx
uniprot id: H2N2A0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:olgpcpr-gamma
gene id: 8090:olgpcpr-gamma
uniprot id: Q76B51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8090:dcc
gene id: 8090:dcc
uniprot id: A0A3B3H6B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

8090:LOC101166261
gene id: 8090:LOC101166261
uniprot id: H2LTQ5
names: Subcellular Location Annotation
messages: Membrane

8090:suds3
gene id: 8090:suds3
uniprot id: A0A3B3I6F6
uniprot id: A0A3P9JN15
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101175390
gene id: 8090:LOC101175390
uniprot id: H2MPQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

8090:shtn1
gene id: 8090:shtn1
uniprot id: A0A3B3IIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: Perikaryon
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8090:LOC101174920
gene id: 8090:LOC101174920
uniprot id: A0A3B3HZR7
names: Similarity
messages: Belongs to the BACURD family.

8090:dbndd1
gene id: 8090:dbndd1
uniprot id: A0A3B3H627
uniprot id: A0A3P9H6W0
names: Similarity
messages: Belongs to the dysbindin family.

8090:LOC101167323
gene id: 8090:LOC101167323
uniprot id: A0A3B3H6U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8090:gnrh-r3
gene id: 8090:gnrh-r3
uniprot id: Q76L93
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101171355
gene id: 8090:LOC101171355
uniprot id: A0A3P9JRK4
uniprot id: H2LE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

8090:mcts1
gene id: 8090:mcts1
uniprot id: A0A3B3ICU6
uniprot id: A0A3P9K3D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

8090:grk6
gene id: 8090:grk6
uniprot id: H2MVW1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8090:flvcr1
gene id: 8090:flvcr1
uniprot id: H2N1U0
names: Subcellular Location Annotation
messages: Membrane

8090:sf3a2
gene id: 8090:sf3a2
uniprot id: H2MKF1
names: Similarity
messages: Belongs to the SF3A2 family.

8090:LOC101168516
gene id: 8090:LOC101168516
uniprot id: A0A3P9GZP7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC101174118
gene id: 8090:LOC101174118
uniprot id: H2MIL9
names: Similarity
messages: Belongs to the GADD45 family.

8090:LOC101164629
gene id: 8090:LOC101164629
uniprot id: H2L313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:vdac1
gene id: 8090:vdac1
uniprot id: H2L5X9
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

8090:LOC101156837
gene id: 8090:LOC101156837
uniprot id: H2LGG3
uniprot id: H2LGG6
names: Subcellular Location Annotation
messages: Membrane

8090:serpina10
gene id: 8090:serpina10
uniprot id: H2MMV6
names: Similarity
messages: Belongs to the serpin family.

8090:bud13
gene id: 8090:bud13
uniprot id: H2LM73
names: Similarity
messages: Belongs to the CWC26 family.

8090:nipal2
gene id: 8090:nipal2
uniprot id: H2LC76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8090:ptpra
gene id: 8090:ptpra
uniprot id: Q76K58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

8090:LOC100301613
gene id: 8090:LOC100301613
uniprot id: C1K2Z4
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC105355131
gene id: 8090:LOC105355131
uniprot id: A0A3B3H5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

8090:top2b
gene id: 8090:top2b
uniprot id: A0A3B3HYR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

8090:LOC101172034
gene id: 8090:LOC101172034
uniprot id: H2MPW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

8090:LOC101164468
gene id: 8090:LOC101164468
uniprot id: A0A3B3IF42
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101156647
gene id: 8090:LOC101156647
uniprot id: H2MLN5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

8090:nipsnap2
gene id: 8090:nipsnap2
uniprot id: A0A3B3H7G9
names: Similarity
messages: Belongs to the NipSnap family.

8090:ccdc47
gene id: 8090:ccdc47
uniprot id: A0A3B3HSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC47 family.
messages: Rough endoplasmic reticulum membrane

8090:cd34
gene id: 8090:cd34
uniprot id: H2LTX5
names: Subcellular Location Annotation
messages: Membrane

8090:mc6ast2
gene id: 8090:mc6ast2
uniprot id: A0A3P9K1P2
uniprot id: H2L3H2
uniprot id: Q14TH7
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101172385
gene id: 8090:LOC101172385
uniprot id: H2MZR4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

8090:st6gal2
gene id: 8090:st6gal2
uniprot id: Q5K027
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Golgi stack membrane
messages: Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.

8090:LOC101175202
gene id: 8090:LOC101175202
uniprot id: A0A3P9MQI6
uniprot id: H2M9P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8090:LOC101173701
gene id: 8090:LOC101173701
uniprot id: A0A3B3IK86
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

8090:ogg1
gene id: 8090:ogg1
uniprot id: H2M4W6
names: Similarity
messages: Belongs to the type-1 OGG1 family.

8090:mrpl40
gene id: 8090:mrpl40
uniprot id: A0A3B3IFD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

8090:pxn
gene id: 8090:pxn
uniprot id: A0A3B3IH25
uniprot id: H2LZB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cytoskeleton
messages: focal adhesion

8090:foxb2
gene id: 8090:foxb2
uniprot id: C1K2Y3
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101157167
gene id: 8090:LOC101157167
uniprot id: A0A3P9JEG0
uniprot id: H2MI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8090:LOC101174720
gene id: 8090:LOC101174720
uniprot id: H2MVE0
names: Similarity
messages: Belongs to the serpin family.

8090:gdpd2
gene id: 8090:gdpd2
uniprot id: H2L909
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8090:eftud2
gene id: 8090:eftud2
uniprot id: H2LD77
names: Subcellular Location Annotation
messages: Nucleus

8090:cstf2
gene id: 8090:cstf2
uniprot id: H2L796
uniprot id: H2L798
names: Subcellular Location Annotation
messages: Nucleus

8090:gapvd1
gene id: 8090:gapvd1
uniprot id: A0A3B3I4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAPVD1 family.
messages: Membrane

8090:LOC101165635
gene id: 8090:LOC101165635
uniprot id: A0A3B3I7I0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8090:LOC101162684
gene id: 8090:LOC101162684
uniprot id: H2LNB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

8090:slit1
gene id: 8090:slit1
uniprot id: H2LV14
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101170587
gene id: 8090:LOC101170587
uniprot id: H2LU65
names: Similarity
messages: Belongs to the peptidase M24 family.

8090:LOC101166547
gene id: 8090:LOC101166547
uniprot id: H2MPQ7
names: Similarity
messages: Belongs to the intermediate filament family.

8090:dio2
gene id: 8090:dio2
uniprot id: B3Y056
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

8090:mrpl46
gene id: 8090:mrpl46
uniprot id: H2MI13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

8090:pck2
gene id: 8090:pck2
uniprot id: A0A3P9K5K6
uniprot id: H2LPA9
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

8090:stk11ip
gene id: 8090:stk11ip
uniprot id: H2LA60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

8090:LOC101160439
gene id: 8090:LOC101160439
uniprot id: A0A3B3IAL3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8090:LOC101175058
gene id: 8090:LOC101175058
uniprot id: H2MWU8
names: Similarity
messages: Belongs to the MAGUK family.

8090:nob1
gene id: 8090:nob1
uniprot id: H2MX98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

8090:exosc2
gene id: 8090:exosc2
uniprot id: H2LTB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

8090:rasgrp2
gene id: 8090:rasgrp2
uniprot id: A0A3B3IBF3
names: Similarity
messages: Belongs to the RASGRP family.

8090:ddah1
gene id: 8090:ddah1
uniprot id: H2M4Q8
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

8090:rtraf
gene id: 8090:rtraf
uniprot id: H2LFQ4
names: Similarity
messages: Belongs to the RTRAF family.

8090:LOC101166962
gene id: 8090:LOC101166962
uniprot id: A0A3B3HJL9
uniprot id: A0A3P9KZR2
names: Similarity
messages: Belongs to the TAFA family.

8090:LOC101163104
gene id: 8090:LOC101163104
uniprot id: A0A3P9MJL9
uniprot id: H2L914
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:nitr20
gene id: 8090:nitr20
uniprot id: B3TZA8
names: Subcellular Location Annotation
messages: Membrane

8090:tmco3
gene id: 8090:tmco3
uniprot id: H2LIU7
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101165095
gene id: 8090:LOC101165095
uniprot id: H2MGQ9
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

8090:dcaf13
gene id: 8090:dcaf13
uniprot id: H2LAM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

8090:LOC101175674
gene id: 8090:LOC101175674
uniprot id: A0A3B3HW56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

8090:atp2b2
gene id: 8090:atp2b2
uniprot id: A0A3B3H4H1
uniprot id: A0A3B3HR57
uniprot id: A0A3B3IF53
uniprot id: H2LIQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:npy
gene id: 8090:npy
uniprot id: A7UDN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

8090:LOC101173585
gene id: 8090:LOC101173585
uniprot id: A0A3B3H5I7
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101171318
gene id: 8090:LOC101171318
uniprot id: A0A3B3IFT7
names: Similarity
messages: Belongs to the lipin family.

8090:mmyhl1
gene id: 8090:mmyhl1
uniprot id: A0A3P9L7J0
uniprot id: C4TIP2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8090:LOC101167684
gene id: 8090:LOC101167684
uniprot id: H2L2X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

8090:LOC101168675
gene id: 8090:LOC101168675
uniprot id: A0A3P9I5H1
uniprot id: H2L385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:srp19
gene id: 8090:srp19
uniprot id: A0A3B3IFP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

8090:LOC101165658
gene id: 8090:LOC101165658
uniprot id: H2LJ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8090:tmem121
gene id: 8090:tmem121
uniprot id: A0A3P9MFC0
uniprot id: H2M804
names: Similarity
messages: Belongs to the TMEM121 family.

8090:alg6
gene id: 8090:alg6
uniprot id: H2M3G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:bola1
gene id: 8090:bola1
uniprot id: H2MNU3
names: Similarity
messages: Belongs to the BolA/IbaG family.

8090:nt5c2
gene id: 8090:nt5c2
uniprot id: A0A3P9K3H4
uniprot id: H2MCG8
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

8090:LOC101168959
gene id: 8090:LOC101168959
uniprot id: A0A3B3HTE3
uniprot id: A0A3P9HYS7
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8090:ndufv2
gene id: 8090:ndufv2
uniprot id: H2LG76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

8090:LOC101172193
gene id: 8090:LOC101172193
uniprot id: A0A3B3I0J2
uniprot id: H2LSH0
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

8090:ube2s
gene id: 8090:ube2s
uniprot id: A0A3P9HXH8
uniprot id: H2M728
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:ndp
gene id: 8090:ndp
uniprot id: A0A3B3HM19
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101155570
gene id: 8090:LOC101155570
uniprot id: A0A3B3H826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

8090:LOC101158812
gene id: 8090:LOC101158812
uniprot id: H2MB30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

8090:capn7
gene id: 8090:capn7
uniprot id: A0A3B3I139
names: Similarity
messages: Belongs to the peptidase C2 family.

8090:smc1b
gene id: 8090:smc1b
uniprot id: Q765Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

8090:LOC101172156
gene id: 8090:LOC101172156
uniprot id: H2L584
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:wars2
gene id: 8090:wars2
uniprot id: A0A3B3H9G4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8090:tmed6
gene id: 8090:tmed6
uniprot id: H2MDY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:gnas
gene id: 8090:gnas
uniprot id: A0A3P9MGI6
uniprot id: H2LF32
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

8090:LOC101164480
gene id: 8090:LOC101164480
uniprot id: A0A3B3H3T3
uniprot id: A0A3B3HXT0
uniprot id: A0A3B3I7T2
uniprot id: A0A3P9H1G8
uniprot id: A0A3P9H1U8
uniprot id: A0A3P9KD36
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8090:atp10a
gene id: 8090:atp10a
uniprot id: H2MM49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8090:rpa1
gene id: 8090:rpa1
uniprot id: H2LJD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

8090:LOC101163426
gene id: 8090:LOC101163426
uniprot id: A0A3B3IBE0
uniprot id: A0A3P9LAP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8090:LOC101175374
gene id: 8090:LOC101175374
uniprot id: A0A3P9MF16
uniprot id: H2L744
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101174591
gene id: 8090:LOC101174591
uniprot id: H2MJG3
names: Similarity
messages: Belongs to the SEC6 family.

8090:ugcg
gene id: 8090:ugcg
uniprot id: A0A3B3HQH9
uniprot id: A0A3P9MJS4
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

8090:vip
gene id: 8090:vip
uniprot id: A0A3P9JP72
uniprot id: A0A8D5FPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8090:slc25a14
gene id: 8090:slc25a14
uniprot id: H2ML10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:bcl7b
gene id: 8090:bcl7b
uniprot id: A0A3P9MB42
uniprot id: H2M7K8
names: Similarity
messages: Belongs to the BCL7 family.

8090:LOC101158318
gene id: 8090:LOC101158318
uniprot id: A0A3B3HZR2
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

8090:LOC101160235
gene id: 8090:LOC101160235
uniprot id: H2LDK9
names: Similarity
messages: Belongs to the IFRD family.

8090:atg101
gene id: 8090:atg101
uniprot id: A0A3B3HDD2
uniprot id: A0A3P9JS99
names: Similarity
messages: Belongs to the ATG101 family.

8090:polr3c
gene id: 8090:polr3c
uniprot id: H2M2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

8090:LOC105353609
gene id: 8090:LOC105353609
uniprot id: A0A3B3IM84
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:fen1
gene id: 8090:fen1
uniprot id: A0A3B3HYK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Mitochondrion
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

8090:LOC101168136
gene id: 8090:LOC101168136
uniprot id: H2MFQ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8090:mdhb
gene id: 8090:mdhb
uniprot id: A0A3P9L8T0
uniprot id: Q801E7
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

8090:slc2a11b
gene id: 8090:slc2a11b
uniprot id: H2LVH2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8090:LOC101173147
gene id: 8090:LOC101173147
uniprot id: H2MI50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8090:plac8l1
gene id: 8090:plac8l1
uniprot id: A0A3B3HCQ0
uniprot id: A0A3P9H658
names: Similarity
messages: Belongs to the cornifelin family.

8090:LOC101159837
gene id: 8090:LOC101159837
uniprot id: H2M7N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8090:LOC101167491
gene id: 8090:LOC101167491
uniprot id: A0A3B3H4F2
uniprot id: A0A3B3HHK6
uniprot id: A0A3B3HNC0
uniprot id: A0A3B3IPE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101168740
gene id: 8090:LOC101168740
uniprot id: H2M0X6
names: Subcellular Location Annotation
messages: Nucleus

8090:ccdc149
gene id: 8090:ccdc149
uniprot id: H2LJ92
names: Similarity
messages: Belongs to the CCDC149 family.

8090:LOC101168603
gene id: 8090:LOC101168603
uniprot id: H2L4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

8090:LOC101168654
gene id: 8090:LOC101168654
uniprot id: A0A3B3HJ64
uniprot id: A0A3P9MD65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8090:tead1
gene id: 8090:tead1
uniprot id: A0A3P9M3Q9
uniprot id: H2LTA8
names: Subcellular Location Annotation
messages: Nucleus

8090:pcnx4
gene id: 8090:pcnx4
uniprot id: H2MM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

8090:LOC101161334
gene id: 8090:LOC101161334
uniprot id: A0A3B3I2E4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8090:LOC101155107
gene id: 8090:LOC101155107
uniprot id: H2LGM1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101175513
gene id: 8090:LOC101175513
uniprot id: H2LQE6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8090:slain1
gene id: 8090:slain1
uniprot id: H2M7I2
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

8090:exosc1
gene id: 8090:exosc1
uniprot id: H2M7S4
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101173059
gene id: 8090:LOC101173059
uniprot id: H2LFG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

8090:LOC101168134
gene id: 8090:LOC101168134
uniprot id: H2LJ26
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

8090:rpl18
gene id: 8090:rpl18
uniprot id: A0A3B3IKB7
uniprot id: A0A3P9KFT3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

8090:immt
gene id: 8090:immt
uniprot id: H2N296
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

8090:LOC101157382
gene id: 8090:LOC101157382
uniprot id: H2L6T9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:naa10
gene id: 8090:naa10
uniprot id: A0A3P9IQE5
uniprot id: H2LS04
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

8090:LOC101171656
gene id: 8090:LOC101171656
uniprot id: H2L7I5
names: Subcellular Location Annotation
messages: cytoskeleton

8090:chmp1b
gene id: 8090:chmp1b
uniprot id: A0A3P9HBC2
names: Similarity
messages: Belongs to the SNF7 family.

8090:LOC101170577
gene id: 8090:LOC101170577
uniprot id: A0A3B3HW12
uniprot id: A0A3P9LVT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

8090:fgb
gene id: 8090:fgb
uniprot id: H2LB33
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

8090:zc3hc1
gene id: 8090:zc3hc1
uniprot id: H2MHF2
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC105355770
gene id: 8090:LOC105355770
uniprot id: A0A3B3H4H2
names: Subcellular Location Annotation
messages: Membrane

8090:hceb
gene id: 8090:hceb
uniprot id: P31581
names: Cofactor
names: Developmental Stage
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In medaka the hatching enzyme system is composed of two distinct proteases, the high choriolytic enzyme (HCE), of which there are two isoforms, and the low choriolytic enzyme (LCE).
messages: Participates in the breakdown of the egg envelope, which is derived from the egg extracellular matrix, at the time of hatching. Thus allowing the newly hatched fish to swim free. HCE binds tightly to the egg envelope while it exerts the choriolytic swelling action.
messages: Production of the protein starts in day 2 to day 3 embryos and increases thereafter until hatching.
messages: Zymogen granule

8090:LOC101162715
gene id: 8090:LOC101162715
uniprot id: H2LU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8090:st8sia6
gene id: 8090:st8sia6
uniprot id: A2BCP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:evc2
gene id: 8090:evc2
uniprot id: H2MQ97
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

8090:atg2a
gene id: 8090:atg2a
uniprot id: H2LAR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

8090:lipg
gene id: 8090:lipg
uniprot id: H2L8Y7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:osbpl9
gene id: 8090:osbpl9
uniprot id: A0A3B3HS53
uniprot id: H2MS00
names: Similarity
messages: Belongs to the OSBP family.

8090:LOC101166180
gene id: 8090:LOC101166180
uniprot id: H2MQD1
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

8090:LOC101157251
gene id: 8090:LOC101157251
uniprot id: H2LER4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC105355883
gene id: 8090:LOC105355883
uniprot id: H2LJ71
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:poc5
gene id: 8090:poc5
uniprot id: H2M065
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

8090:phc1
gene id: 8090:phc1
uniprot id: A0A3B3IHX7
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101156319
gene id: 8090:LOC101156319
uniprot id: H2LRQ0
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101163412
gene id: 8090:LOC101163412
uniprot id: H2LAC1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8090:ndufs5
gene id: 8090:ndufs5
uniprot id: A0A3B3H4G2
uniprot id: A0A3P9M683
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

8090:ccdc43
gene id: 8090:ccdc43
uniprot id: H2LH43
names: Similarity
messages: Belongs to the CCDC43 family.

8090:LOC101156472
gene id: 8090:LOC101156472
uniprot id: A0A3P9J0S2
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8090:LOC101157737
gene id: 8090:LOC101157737
uniprot id: A0A3P9MBC0
uniprot id: H2LXF6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8090:nip7
gene id: 8090:nip7
uniprot id: A0A3B3II55
uniprot id: A0A3P9GXT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

8090:otop1
gene id: 8090:otop1
uniprot id: H2LWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

8090:LOC101165730
gene id: 8090:LOC101165730
uniprot id: H2MCJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8090:hspa13
gene id: 8090:hspa13
uniprot id: A0A3B3IB59
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8090:ndufb3
gene id: 8090:ndufb3
uniprot id: H2M754
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

8090:LOC101160002
gene id: 8090:LOC101160002
uniprot id: A0A3P9MEY2
uniprot id: H2LFD6
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC101162235
gene id: 8090:LOC101162235
uniprot id: A0A3P9J3K4
uniprot id: H2LTU7
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8090:tpm3
gene id: 8090:tpm3
uniprot id: A0A3P9HQJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8090:LOC101157482
gene id: 8090:LOC101157482
uniprot id: H2LJB2
names: Subcellular Location Annotation
messages: Cytoplasm

8090:aifm1
gene id: 8090:aifm1
uniprot id: A0A3B3IP15
uniprot id: H2M0Z1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

8090:creg1
gene id: 8090:creg1
uniprot id: H2L6F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

8090:LOC101164922
gene id: 8090:LOC101164922
uniprot id: H2MLU6
names: Similarity
messages: Belongs to the peptidase C1 family.

8090:LOC101174147
gene id: 8090:LOC101174147
uniprot id: H2MM34
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

8090:rag2
gene id: 8090:rag2
uniprot id: H2M925
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

8090:iapp
gene id: 8090:iapp
uniprot id: H2LXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
messages: Secreted

8090:tsnare1
gene id: 8090:tsnare1
uniprot id: A0A3B3HMV9
names: Similarity
messages: Belongs to the syntaxin family.

8090:LOC101161232
gene id: 8090:LOC101161232
uniprot id: H2LSV4
names: Similarity
messages: Belongs to the profilin family.

8090:LOC101168409
gene id: 8090:LOC101168409
uniprot id: H2MFB2
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

8090:LOC101155189
gene id: 8090:LOC101155189
uniprot id: H2L4F2
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

8090:LOC101165161
gene id: 8090:LOC101165161
uniprot id: A0A3B3HJB3
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

8090:selenoi
gene id: 8090:selenoi
uniprot id: A0A3P9JEV6
uniprot id: H2M3U0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8090:hspb8
gene id: 8090:hspb8
uniprot id: A0A3B3HJ66
uniprot id: A0A3P9KK80
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8090:tpra1
gene id: 8090:tpra1
uniprot id: H2MQ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

8090:LOC101171653
gene id: 8090:LOC101171653
uniprot id: H2LZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

8090:boc
gene id: 8090:boc
uniprot id: H2LZ28
names: Subcellular Location Annotation
messages: Membrane

8090:eda
gene id: 8090:eda
uniprot id: A0A3P9M075
uniprot id: H2LQ48
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8090:adck2
gene id: 8090:adck2
uniprot id: H2LBG5
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

8090:cdh24
gene id: 8090:cdh24
uniprot id: H2MAE7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8090:aadac
gene id: 8090:aadac
uniprot id: H2LN66
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8090:nop14
gene id: 8090:nop14
uniprot id: H2LM63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

8090:aatf
gene id: 8090:aatf
uniprot id: H2MET1
names: Similarity
messages: Belongs to the AATF family.

8090:LOC101167637
gene id: 8090:LOC101167637
uniprot id: H2MLP7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8090:LOC101159986
gene id: 8090:LOC101159986
uniprot id: A0A3P9H852
uniprot id: H2MI77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8090:LOC101163578
gene id: 8090:LOC101163578
uniprot id: A0A3P9K5Y1
uniprot id: H2ML41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8090:LOC101160795
gene id: 8090:LOC101160795
uniprot id: H2N2S6
names: Similarity
messages: Belongs to the FBPase class 1 family.

8090:LOC101170867
gene id: 8090:LOC101170867
uniprot id: A0A3B3HWJ7
names: Subcellular Location Annotation
messages: Membrane

8090:parpbp
gene id: 8090:parpbp
uniprot id: A0A3B3HC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

8090:LOC101160347
gene id: 8090:LOC101160347
uniprot id: H2LK51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

8090:LOC101166116
gene id: 8090:LOC101166116
uniprot id: A0A3B3I201
names: Similarity
messages: Belongs to the CARF family.

8090:cdc20
gene id: 8090:cdc20
uniprot id: B6ZIW2
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

8090:mmyhemb1
gene id: 8090:mmyhemb1
uniprot id: C4TIP1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8090:gnl2
gene id: 8090:gnl2
uniprot id: H2MI81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

8090:trnt1
gene id: 8090:trnt1
uniprot id: H2LDE0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

8090:slc25a35
gene id: 8090:slc25a35
uniprot id: A0A3P9HKX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:LOC101157253
gene id: 8090:LOC101157253
uniprot id: A0A3P9MPF0
uniprot id: H2LGP1
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101158653
gene id: 8090:LOC101158653
uniprot id: A0A3B3H9U2
uniprot id: A0A3P9LCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

8090:slc31a2
gene id: 8090:slc31a2
uniprot id: A0A3P9K697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8090:LOC101164721
gene id: 8090:LOC101164721
uniprot id: H2L7I1
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8090:ess2
gene id: 8090:ess2
uniprot id: A0A3P9H6P8
uniprot id: H2LWN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

8090:ing5
gene id: 8090:ing5
uniprot id: H2L7U8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8090:wtap
gene id: 8090:wtap
uniprot id: H2MDF2
names: Similarity
messages: Belongs to the fl(2)d family.

8090:eif2b1
gene id: 8090:eif2b1
uniprot id: H2L439
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

8090:alg12
gene id: 8090:alg12
uniprot id: H2M7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC105356428
gene id: 8090:LOC105356428
uniprot id: A0A3B3HHV4
names: Similarity
messages: Belongs to the peptidase C19 family.

8090:ndufaf4
gene id: 8090:ndufaf4
uniprot id: H2MUN9
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

8090:tmem255b
gene id: 8090:tmem255b
uniprot id: H2LIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

8090:zfyve27
gene id: 8090:zfyve27
uniprot id: A0A3B3I4Z4
uniprot id: H2M7I5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

8090:hprt1
gene id: 8090:hprt1
uniprot id: A0A3B3HF46
uniprot id: A0A3P9HZJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

8090:coll
gene id: 8090:coll
uniprot id: Q4AED4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:LOC101174287
gene id: 8090:LOC101174287
uniprot id: A0A3P9MCN2
uniprot id: H2MA42
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8090:LOC101159753
gene id: 8090:LOC101159753
uniprot id: H2MTS1
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8090:LOC101171851
gene id: 8090:LOC101171851
uniprot id: A0A3P9LGL6
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:gal3st1
gene id: 8090:gal3st1
uniprot id: H2LUX3
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8090:LOC101167292
gene id: 8090:LOC101167292
uniprot id: A0A3B3INA2
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

8090:foxj1
gene id: 8090:foxj1
uniprot id: C1K2Z8
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101158483
gene id: 8090:LOC101158483
uniprot id: A0A3P9I282
uniprot id: H2M635
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

8090:pno1
gene id: 8090:pno1
uniprot id: Q6VBQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNO1 family.
messages: Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
messages: nucleolus

8090:LOC101165435
gene id: 8090:LOC101165435
uniprot id: H2MQ45
names: Subcellular Location Annotation
messages: cytoskeleton

8090:hgd
gene id: 8090:hgd
uniprot id: A0A3B3IKU7
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

8090:LOC101163035
gene id: 8090:LOC101163035
uniprot id: H2M4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

8090:LOC105357076
gene id: 8090:LOC105357076
uniprot id: A0A3B3HYK8
uniprot id: A0A3P9LD16
names: Subcellular Location Annotation
messages: Membrane

8090:cers6
gene id: 8090:cers6
uniprot id: H2MRE2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8090:gtf2ird1
gene id: 8090:gtf2ird1
uniprot id: A0A3B3HKN3
uniprot id: H2MKG9
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101156727
gene id: 8090:LOC101156727
uniprot id: A0A3P9IIQ7
uniprot id: H2MBT7
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8090:LOC101173896
gene id: 8090:LOC101173896
uniprot id: A0A3P9IHW2
uniprot id: H2LE63
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8090:sost
gene id: 8090:sost
uniprot id: A0A3B3H969
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101169574
gene id: 8090:LOC101169574
uniprot id: H2MVE3
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101171587
gene id: 8090:LOC101171587
uniprot id: A0A3P9LV54
uniprot id: H2M7F8
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

8090:hce
gene id: 8090:hce
uniprot id: P31580
names: Cofactor
names: Developmental Stage
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In medaka the hatching enzyme system is composed of two distinct proteases, the high choriolytic enzyme (HCE), of which there are two isoforms, and the low choriolytic enzyme (LCE).
messages: Participates in the breakdown of the egg envelope, which is derived from the egg extracellular matrix, at the time of hatching. Thus allowing the newly hatched fish to swim free. HCE binds tightly to the egg envelope while it exerts the choriolytic swelling action.
messages: Production of the protein starts in day 2 to day 3 embryos and increases thereafter until hatching.
messages: Zymogen granule

8090:cdk8
gene id: 8090:cdk8
uniprot id: A0A3P9HZH4
uniprot id: H2LYC9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:rpl6
gene id: 8090:rpl6
uniprot id: A0A3P9JG86
uniprot id: H2LB58
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

8090:LOC101155572
gene id: 8090:LOC101155572
uniprot id: H2MYY9
names: Subcellular Location Annotation
messages: Membrane

8090:tiparp
gene id: 8090:tiparp
uniprot id: A0A3B3I0L9
names: Similarity
messages: Belongs to the ARTD/PARP family.

8090:kcnk2
gene id: 8090:kcnk2
uniprot id: H2MSD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8090:phox2b
gene id: 8090:phox2b
uniprot id: H2N0H6
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101169100
gene id: 8090:LOC101169100
uniprot id: H2M6G5
names: Similarity
messages: Belongs to the GCF family.

8090:LOC101170198
gene id: 8090:LOC101170198
uniprot id: A0A3B3H5A7
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

8090:LOC101173575
gene id: 8090:LOC101173575
uniprot id: H2LHB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

8090:LOC101172768
gene id: 8090:LOC101172768
uniprot id: A0A3B3HX58
uniprot id: A0A3B3I2A7
names: Subcellular Location Annotation
messages: Membrane

8090:b3gat1
gene id: 8090:b3gat1
uniprot id: Q5CB01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:dhx58
gene id: 8090:dhx58
uniprot id: A0A3B3H6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

8090:LOC101164189
gene id: 8090:LOC101164189
uniprot id: H2MFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:LOC101163243
gene id: 8090:LOC101163243
uniprot id: H2LLG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

8090:LOC101160340
gene id: 8090:LOC101160340
uniprot id: H2ML85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101171668
gene id: 8090:LOC101171668
uniprot id: H2LJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

8090:tdrd5
gene id: 8090:tdrd5
uniprot id: A0A3B3HSQ2
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101173583
gene id: 8090:LOC101173583
uniprot id: H2LAK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC101155792
gene id: 8090:LOC101155792
uniprot id: H2LGI5
names: Subcellular Location Annotation
messages: Membrane

8090:mrpl52
gene id: 8090:mrpl52
uniprot id: A0A3B3I2I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

8090:tubgcp2
gene id: 8090:tubgcp2
uniprot id: H2MBC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

8090:skap1
gene id: 8090:skap1
uniprot id: A0A3B3ID96
names: Similarity
messages: Belongs to the SKAP family.

8090:ctnnbip1
gene id: 8090:ctnnbip1
uniprot id: A0A3P9H7H6
names: Similarity
messages: Belongs to the CTNNBIP1 family.

8090:LOC101157638
gene id: 8090:LOC101157638
uniprot id: H2LT47
names: Subcellular Location Annotation
messages: Membrane

8090:tsen54
gene id: 8090:tsen54
uniprot id: A0A3B3H9E4
names: Similarity
messages: Belongs to the SEN54 family.

8090:LOC101160779
gene id: 8090:LOC101160779
uniprot id: H2MNG6
names: Similarity
messages: Belongs to the opioid neuropeptide precursor family.

8090:stx2
gene id: 8090:stx2
uniprot id: A0A3B3HK02
names: Similarity
messages: Belongs to the syntaxin family.

8090:LOC101173499
gene id: 8090:LOC101173499
uniprot id: H2LSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8090:cap1
gene id: 8090:cap1
uniprot id: H2M199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

8090:hs3st5
gene id: 8090:hs3st5
uniprot id: A0A3B3II87
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:LOC101175691
gene id: 8090:LOC101175691
uniprot id: H2M2C3
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101166830
gene id: 8090:LOC101166830
uniprot id: A0A3B3IDA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

8090:metap2
gene id: 8090:metap2
uniprot id: H2MQ25
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

8090:wdr18
gene id: 8090:wdr18
uniprot id: A0A3P9J3K7
uniprot id: H2L323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Dynein axonemal particle
messages: nucleolus
messages: nucleoplasm

8090:foxc1
gene id: 8090:foxc1
uniprot id: C1K2Y4
names: Subcellular Location Annotation
messages: Nucleus

8090:dmc1
gene id: 8090:dmc1
uniprot id: A0A3P9KC00
uniprot id: B5T1R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. DMC1 subfamily.
messages: May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
messages: Nucleus

8090:LOC101159064
gene id: 8090:LOC101159064
uniprot id: A0A3P9HMI5
uniprot id: B6F103
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101173791
gene id: 8090:LOC101173791
uniprot id: H2L8Z7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:atp2a1
gene id: 8090:atp2a1
uniprot id: A0A3P9KS76
uniprot id: H2M9M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8090:LOC100125495
gene id: 8090:LOC100125495
uniprot id: H2LR17
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8090:LOC101156356
gene id: 8090:LOC101156356
uniprot id: A0A3B3HZE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

8090:tmem45a
gene id: 8090:tmem45a
uniprot id: H2MNA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

8090:pusl1
gene id: 8090:pusl1
uniprot id: A0A3B3III4
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8090:LOC101165331
gene id: 8090:LOC101165331
uniprot id: H2LSA4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:rpl37
gene id: 8090:rpl37
uniprot id: A0A3B3IKU3
uniprot id: A0A3P9JDI9
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

8090:LOC101171113
gene id: 8090:LOC101171113
uniprot id: H2M8T7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

8090:LOC105354711
gene id: 8090:LOC105354711
uniprot id: A0A3B3HU74
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101173980
gene id: 8090:LOC101173980
uniprot id: H2MA56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8090:greb1l
gene id: 8090:greb1l
uniprot id: A0A3B3HPN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

8090:LOC101158124
gene id: 8090:LOC101158124
uniprot id: H2LZX9
names: Similarity
messages: Belongs to the peptidase S28 family.

8090:LOC101155674
gene id: 8090:LOC101155674
uniprot id: H2LRU1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.

8090:tmtops2
gene id: 8090:tmtops2
uniprot id: R9R6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8090:chmp6
gene id: 8090:chmp6
uniprot id: H2N2I5
names: Similarity
messages: Belongs to the SNF7 family.

8090:LOC101164669
gene id: 8090:LOC101164669
uniprot id: A0A3B3I5T7
uniprot id: A0A3P9I366
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:rnaseh2b
gene id: 8090:rnaseh2b
uniprot id: H2M8M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

8090:med4
gene id: 8090:med4
uniprot id: A0A3P9J3A6
uniprot id: H2MGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8090:LOC101170934
gene id: 8090:LOC101170934
uniprot id: H2MSN0
names: Similarity
messages: Belongs to the arrestin family.

8090:LOC101166949
gene id: 8090:LOC101166949
uniprot id: H2MB99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101162030
gene id: 8090:LOC101162030
uniprot id: A0A3B3IMH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8090:gpkow
gene id: 8090:gpkow
uniprot id: H2MHI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus
messages: RNA-binding protein involved in pre-mRNA splicing.

8090:qrsl1
gene id: 8090:qrsl1
uniprot id: H2MU45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

8090:LOC101157905
gene id: 8090:LOC101157905
uniprot id: H2MKJ7
names: Similarity
messages: Belongs to the ARTD/PARP family.

8090:LOC101169591
gene id: 8090:LOC101169591
uniprot id: A0A3B3I8K6
uniprot id: H2MWA8
names: Similarity
messages: Belongs to the DNase I family.

8090:stk38l
gene id: 8090:stk38l
uniprot id: A0A3P9LRU6
uniprot id: H2M0S3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:LOC101162878
gene id: 8090:LOC101162878
uniprot id: A0A3B3HIN8
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8090:polr2e
gene id: 8090:polr2e
uniprot id: A0A3P9I779
uniprot id: H2MKJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

8090:neu1
gene id: 8090:neu1
uniprot id: H2L9M4
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8090:LOC101158158
gene id: 8090:LOC101158158
uniprot id: A0A3B3HG99
names: Similarity
messages: Belongs to the TENT family.

8090:ndst2
gene id: 8090:ndst2
uniprot id: A0A3B3H7W9
uniprot id: A0A3B3H8N5
uniprot id: A0A3B3HYT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

8090:LOC105354539
gene id: 8090:LOC105354539
uniprot id: A0A3B3IEP2
names: Subcellular Location Annotation
messages: Membrane

8090:slc24a3
gene id: 8090:slc24a3
uniprot id: A0A3P9HUF8
uniprot id: H2LAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8090:LOC101161650
gene id: 8090:LOC101161650
uniprot id: H2LND4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

8090:LOC101163918
gene id: 8090:LOC101163918
uniprot id: H2MG68
names: Similarity
messages: Belongs to the glutamine synthetase family.

8090:lactb2
gene id: 8090:lactb2
uniprot id: H2LML6
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

8090:LOC101168837
gene id: 8090:LOC101168837
uniprot id: A0A3P9K4I6
uniprot id: H2MYP6
names: Subcellular Location Annotation
messages: Membrane

8090:cdh18
gene id: 8090:cdh18
uniprot id: H2MFA8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8090:eri1
gene id: 8090:eri1
uniprot id: A0A3B3HI41
names: Subcellular Location Annotation
messages: Cytoplasm

8090:mlst8
gene id: 8090:mlst8
uniprot id: A0A3P9K8W0
uniprot id: H2LD78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of TORC1 complex. Part of the TORC2 complex.
messages: Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.

8090:LOC101168119
gene id: 8090:LOC101168119
uniprot id: H2LT78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8090:hibadh
gene id: 8090:hibadh
uniprot id: A0A3P9IJU4
uniprot id: H2LTU1
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

8090:ankrd34c
gene id: 8090:ankrd34c
uniprot id: H2LVW3
names: Similarity
messages: Belongs to the ANKRD34 family.

8090:porcn
gene id: 8090:porcn
uniprot id: A0A3B3HYJ1
names: Subcellular Location Annotation
messages: Membrane

8090:rpl13
gene id: 8090:rpl13
uniprot id: A0A3B3I5L0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

8090:ctu2
gene id: 8090:ctu2
uniprot id: A0A3B3H7C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

8090:LOC101165637
gene id: 8090:LOC101165637
uniprot id: H2MFW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101166239
gene id: 8090:LOC101166239
uniprot id: A0A3B3I369
uniprot id: A0A3P9LRU7
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

8090:tatdn2
gene id: 8090:tatdn2
uniprot id: H2L7L9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

8090:LOC101161290
gene id: 8090:LOC101161290
uniprot id: A0A3P9HMI5
uniprot id: B6F103
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:tsen2
gene id: 8090:tsen2
uniprot id: A0A3B3H7Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

8090:prrx1
gene id: 8090:prrx1
uniprot id: A0A3P9IK55
uniprot id: A0A3P9K086
uniprot id: H2ME55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8090:LOC101165880
gene id: 8090:LOC101165880
uniprot id: A0A3B3HGY5
uniprot id: A0A3P9KWS2
uniprot id: A0A3P9KX25
uniprot id: H2LH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

8090:LOC101161808
gene id: 8090:LOC101161808
uniprot id: H2MQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8090:LOC101157019
gene id: 8090:LOC101157019
uniprot id: A0A3B3HD51
uniprot id: A0A3P9L5F4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8090:LOC101175238
gene id: 8090:LOC101175238
uniprot id: Q8AYQ7
names: Similarity
messages: Belongs to the globin family.

8090:bud23
gene id: 8090:bud23
uniprot id: A0A3B3HI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

8090:pithd1
gene id: 8090:pithd1
uniprot id: H2LTG1
names: Similarity
messages: Belongs to the PITHD1 family.

8090:mcm9
gene id: 8090:mcm9
uniprot id: H2MKY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

8090:LOC101157991
gene id: 8090:LOC101157991
uniprot id: H2MLQ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:chpf2
gene id: 8090:chpf2
uniprot id: H2M8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8090:vps33b
gene id: 8090:vps33b
uniprot id: A0A3B3IN89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8090:ghitm
gene id: 8090:ghitm
uniprot id: H2M011
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8090:polr3a
gene id: 8090:polr3a
uniprot id: H2LYL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

8090:fpgs
gene id: 8090:fpgs
uniprot id: H2MVP5
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

8090:LOC101171021
gene id: 8090:LOC101171021
uniprot id: A0A3B3IEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:LOC101170993
gene id: 8090:LOC101170993
uniprot id: A0A3P9JHJ8
uniprot id: H2MIK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

8090:xdh
gene id: 8090:xdh
uniprot id: H2L694
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Peroxisome

8090:mmachc
gene id: 8090:mmachc
uniprot id: H2MID2
names: Similarity
messages: Belongs to the MMACHC family.

8090:fignl1
gene id: 8090:fignl1
uniprot id: H2N205
names: Similarity
messages: Belongs to the AAA ATPase family.

8090:LOC101163308
gene id: 8090:LOC101163308
uniprot id: H2N1U3
names: Subcellular Location Annotation
messages: Membrane

8090:trmt112
gene id: 8090:trmt112
uniprot id: H2LAK9
names: Similarity
messages: Belongs to the TRM112 family.

8090:LOC101155505
gene id: 8090:LOC101155505
uniprot id: H2MQE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

8090:ppp2r5a
gene id: 8090:ppp2r5a
uniprot id: H2M9K9
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8090:psen2
gene id: 8090:psen2
uniprot id: H2N0U7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

8090:LOC101161603
gene id: 8090:LOC101161603
uniprot id: A0A3B3HF47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

8090:LOC101164051
gene id: 8090:LOC101164051
uniprot id: H2M5B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8090:akirin2
gene id: 8090:akirin2
uniprot id: H2M792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8090:LOC101173389
gene id: 8090:LOC101173389
uniprot id: H2MIF1
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8090:arpc5
gene id: 8090:arpc5
uniprot id: A0A3P9HHV6
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

8090:prkaa2
gene id: 8090:prkaa2
uniprot id: H2L8J1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

8090:LOC101170257
gene id: 8090:LOC101170257
uniprot id: A0A3B3HVX1
names: Subcellular Location Annotation
messages: extracellular space

8090:tfap2a
gene id: 8090:tfap2a
uniprot id: A0A3P9IJ22
uniprot id: A0A3P9LRA6
uniprot id: H2LQI6
uniprot id: H2LQI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

8090:LOC101167983
gene id: 8090:LOC101167983
uniprot id: A0A3P9KBL6
uniprot id: H2M833
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

8090:LOC101162909
gene id: 8090:LOC101162909
uniprot id: A0A3B3I3X1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

8090:tmem19
gene id: 8090:tmem19
uniprot id: H2MS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

8090:tmem53
gene id: 8090:tmem53
uniprot id: A0A3B3I8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

8090:prdx2
gene id: 8090:prdx2
uniprot id: A0A3P9IG78
uniprot id: H2MHT9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

8090:hoxb1
gene id: 8090:hoxb1
uniprot id: Q3V613
names: Subcellular Location Annotation
messages: Nucleus

8090:srd5a1
gene id: 8090:srd5a1
uniprot id: H2MH93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

8090:LOC101168573
gene id: 8090:LOC101168573
uniprot id: A0A3B3H3W7
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101169729
gene id: 8090:LOC101169729
uniprot id: A0A3P9IAI7
uniprot id: H2LYZ8
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101166216
gene id: 8090:LOC101166216
uniprot id: H2L3L8
names: Similarity
messages: Belongs to the CDI family.

8090:stag1
gene id: 8090:stag1
uniprot id: A0A3P9LEY2
uniprot id: H2M9J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

8090:LOC101171840
gene id: 8090:LOC101171840
uniprot id: A0A3P9HEF3
uniprot id: H2MRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8090:LOC101162765
gene id: 8090:LOC101162765
uniprot id: A0A3P9HDQ3
uniprot id: A0A3P9IZZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

8090:LOC101164795
gene id: 8090:LOC101164795
uniprot id: A0A3B3HT51
uniprot id: A0A3P9JZZ8
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8090:bmp2
gene id: 8090:bmp2
uniprot id: A0MK36
names: Similarity
messages: Belongs to the TGF-beta family.

8090:eif4enif1
gene id: 8090:eif4enif1
uniprot id: B1NHM3
names: Subcellular Location Annotation
messages: Cytoplasm

8090:lmod3
gene id: 8090:lmod3
uniprot id: H2MEA8
names: Subcellular Location Annotation
messages: cytoskeleton

8090:crh
gene id: 8090:crh
uniprot id: B1Q2A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

8090:LOC101174201
gene id: 8090:LOC101174201
uniprot id: H2LWP2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:tac3
gene id: 8090:tac3
uniprot id: A0A3P9KFH2
uniprot id: I4IYA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

8090:kcnh6
gene id: 8090:kcnh6
uniprot id: A0A3B3HVZ1
names: Subcellular Location Annotation
messages: Membrane

8090:arrb2
gene id: 8090:arrb2
uniprot id: H2MD30
names: Similarity
messages: Belongs to the arrestin family.

8090:LOC101167328
gene id: 8090:LOC101167328
uniprot id: A0A3B3HYA5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:ift20
gene id: 8090:ift20
uniprot id: A0A3P9MM14
uniprot id: H2LWV0
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

8090:znf532
gene id: 8090:znf532
uniprot id: H2LND9
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

8090:api5
gene id: 8090:api5
uniprot id: A0A3B3HG70
names: Similarity
messages: Belongs to the API5 family.

8090:LOC101163046
gene id: 8090:LOC101163046
uniprot id: H2MUB9
uniprot id: H2MUC1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8090:med19
gene id: 8090:med19
uniprot id: A0A3P9L504
uniprot id: H2LET8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8090:ddit3
gene id: 8090:ddit3
uniprot id: A0A3P9MGE2
uniprot id: G5ELX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

8090:slc16a5
gene id: 8090:slc16a5
uniprot id: H2MB83
names: Subcellular Location Annotation
messages: Membrane

8090:tpp1
gene id: 8090:tpp1
uniprot id: H2MLP6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:mettl11b
gene id: 8090:mettl11b
uniprot id: H2ME74
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

8090:lamtor5
gene id: 8090:lamtor5
uniprot id: A0A3P9H3I6
uniprot id: H2LP82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

8090:basp1
gene id: 8090:basp1
uniprot id: A0A3B3I5Z8
names: Similarity
messages: Belongs to the BASP1 family.

8090:polr1e
gene id: 8090:polr1e
uniprot id: H2LKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

8090:neurod2
gene id: 8090:neurod2
uniprot id: H2LEA7
names: Subcellular Location Annotation
messages: Nucleus

8090:stx17
gene id: 8090:stx17
uniprot id: H2LXX6
names: Similarity
messages: Belongs to the syntaxin family.

8090:srm
gene id: 8090:srm
uniprot id: A0A3P9HAL1
uniprot id: H2LKB7
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

8090:gpr135
gene id: 8090:gpr135
uniprot id: H2MV29
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:LOC101155571
gene id: 8090:LOC101155571
uniprot id: A0A3P9HMI5
uniprot id: B6F103
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:taf7l
gene id: 8090:taf7l
uniprot id: A0A3P9MPK7
uniprot id: H2L7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

8090:LOC101159022
gene id: 8090:LOC101159022
uniprot id: H2M1R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

8090:LOC101156445
gene id: 8090:LOC101156445
uniprot id: H2MHJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8090:LOC105353580
gene id: 8090:LOC105353580
uniprot id: A0A3B3HGX6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

8090:psma2
gene id: 8090:psma2
uniprot id: A0A3P9H4U8
uniprot id: H2LP28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8090:LOC101174093
gene id: 8090:LOC101174093
uniprot id: H2LPA5
names: Similarity
messages: Belongs to the DNase II family.

8090:LOC101173929
gene id: 8090:LOC101173929
uniprot id: H2MHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8090:LOC101165082
gene id: 8090:LOC101165082
uniprot id: H2L491
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101156325
gene id: 8090:LOC101156325
uniprot id: H2MJV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8090:LOC101157772
gene id: 8090:LOC101157772
uniprot id: A0A3B3H4Z3
uniprot id: H2LQ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC101163258
gene id: 8090:LOC101163258
uniprot id: H2LKH7
names: Similarity
messages: Belongs to the OSBP family.

8090:alkal2
gene id: 8090:alkal2
uniprot id: A0A3B3I2R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

8090:LOC101160821
gene id: 8090:LOC101160821
uniprot id: H2LT08
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101163271
gene id: 8090:LOC101163271
uniprot id: A0A3B3H5Q2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

8090:LOC101173974
gene id: 8090:LOC101173974
uniprot id: H2MMV1
names: Subcellular Location Annotation
messages: Membrane

8090:lsm8
gene id: 8090:lsm8
uniprot id: A0A3P9H5I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

8090:sema4c
gene id: 8090:sema4c
uniprot id: H2MKF3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101167451
gene id: 8090:LOC101167451
uniprot id: H2LTW7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

8090:smim8
gene id: 8090:smim8
uniprot id: A0A3B3IH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

8090:tyrobp
gene id: 8090:tyrobp
uniprot id: A0A3B3HHZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TYROBP family.
messages: Cell membrane
messages: Membrane

8090:abcd4
gene id: 8090:abcd4
uniprot id: A0A3P9JWQ0
uniprot id: H2MST8
names: Subcellular Location Annotation
messages: Membrane

8090:ranbp9
gene id: 8090:ranbp9
uniprot id: A0A3P9LEX5
uniprot id: D2KVX3
names: Similarity
messages: Belongs to the RANBP9/10 family.

8090:cyp1a
gene id: 8090:cyp1a
uniprot id: Q7T2Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8090:kif26a
gene id: 8090:kif26a
uniprot id: H2MN66
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:LOC101175254
gene id: 8090:LOC101175254
uniprot id: A0A3P9IPY2
uniprot id: H2LXC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:vta1
gene id: 8090:vta1
uniprot id: A0A3B3IGF7
uniprot id: A0A3P9I6U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

8090:ypelb
gene id: 8090:ypelb
uniprot id: A0A3P9HV16
uniprot id: Q65Z53
names: Similarity
messages: Belongs to the yippee family.

8090:trnau1ap
gene id: 8090:trnau1ap
uniprot id: A0A3P9J601
uniprot id: H2M3Q7
names: Similarity
messages: Belongs to the RRM TRSPAP family.

8090:mtfr1l
gene id: 8090:mtfr1l
uniprot id: A0A3P9HS83
uniprot id: H2MIA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

8090:slc25a34
gene id: 8090:slc25a34
uniprot id: H2MVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:relt
gene id: 8090:relt
uniprot id: A0A3B3IC98
names: Similarity
messages: Belongs to the RELT family.

8090:LOC101174524
gene id: 8090:LOC101174524
uniprot id: A0A3B3IJW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8090:ldhd
gene id: 8090:ldhd
uniprot id: A0A3B3H8L7
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

8090:sgpl1
gene id: 8090:sgpl1
uniprot id: H2MG85
names: Similarity
messages: Belongs to the group II decarboxylase family.

8090:LOC101156432
gene id: 8090:LOC101156432
uniprot id: A0A3P9L6S1
uniprot id: H2LQZ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:tusc5
gene id: 8090:tusc5
uniprot id: A0A3B3HAJ4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8090:LOC101157246
gene id: 8090:LOC101157246
uniprot id: A0A3P9LNM8
uniprot id: H2MEG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:kcnab2
gene id: 8090:kcnab2
uniprot id: A0A3B3HPY8
uniprot id: A0A3B3HYN8
uniprot id: A0A3B3IL03
uniprot id: A0A3P9LDJ2
uniprot id: A0A3P9MKS8
uniprot id: A0A3P9ML23
uniprot id: H2LHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

8090:gpr157
gene id: 8090:gpr157
uniprot id: H2LMC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 5 family.
messages: Membrane

8090:LOC101160985
gene id: 8090:LOC101160985
uniprot id: H2LFL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

8090:tmem41a
gene id: 8090:tmem41a
uniprot id: H2MPI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

8090:LOC101160599
gene id: 8090:LOC101160599
uniprot id: A0A3B3INJ3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

8090:rpl23a
gene id: 8090:rpl23a
uniprot id: A0A3P9I1K6
uniprot id: H2LLN8
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

8090:nid1
gene id: 8090:nid1
uniprot id: H2MBD4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8090:stac
gene id: 8090:stac
uniprot id: A0A3B3I2Y9
names: Subcellular Location Annotation
messages: sarcolemma

8090:LOC101165899
gene id: 8090:LOC101165899
uniprot id: A0A3P9LSR2
uniprot id: H2LV79
names: Similarity
messages: Belongs to the CYSTM1 family.

8090:slc13a3
gene id: 8090:slc13a3
uniprot id: A0A3B3IDP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8090:c6h15orf40
gene id: 8090:c6h15orf40
uniprot id: A0A3B3I0M4
names: Similarity
messages: Belongs to the UPF0235 family.

8090:misrii
gene id: 8090:misrii
uniprot id: A4PBT1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

8090:LOC101171986
gene id: 8090:LOC101171986
uniprot id: H2LCP5
names: Similarity
messages: Belongs to the FAM83 family.

8090:LOC101161799
gene id: 8090:LOC101161799
uniprot id: A0A3B3IFD4
uniprot id: A0A3P9KXB4
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101165957
gene id: 8090:LOC101165957
uniprot id: H2N0M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:nup35
gene id: 8090:nup35
uniprot id: A0A3B3IIE7
uniprot id: A0A3P9KFX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

8090:rdh13
gene id: 8090:rdh13
uniprot id: H2LTK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:LOC101161439
gene id: 8090:LOC101161439
uniprot id: A0A3B3IJ08
uniprot id: H2MFZ1
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8090:otub1
gene id: 8090:otub1
uniprot id: A0A3P9KU46
uniprot id: H2M6K9
names: Similarity
messages: Belongs to the peptidase C65 family.

8090:LOC101156799
gene id: 8090:LOC101156799
uniprot id: H2MDE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8090:nme3
gene id: 8090:nme3
uniprot id: H2M887
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8090:LOC101156059
gene id: 8090:LOC101156059
uniprot id: A0A3B3H6P7
uniprot id: A0A3P9KGA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

8090:LOC101167140
gene id: 8090:LOC101167140
uniprot id: A0A3P9M9R4
uniprot id: H2LG11
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8090:slc25a28
gene id: 8090:slc25a28
uniprot id: A0A3B3I205
uniprot id: A0A3P9LQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:LOC101163413
gene id: 8090:LOC101163413
uniprot id: A0A3B3IJ54
uniprot id: A0A3P9J1N0
names: Similarity
messages: Belongs to the SUI1 family.

8090:LOC101159953
gene id: 8090:LOC101159953
uniprot id: A0A3B3IPH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:mapk6
gene id: 8090:mapk6
uniprot id: H2LD47
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

8090:LOC101174071
gene id: 8090:LOC101174071
uniprot id: A0A3B3I4A5
uniprot id: A0A3P9IER2
names: Similarity
messages: Belongs to the stathmin family.

8090:arx
gene id: 8090:arx
uniprot id: A8HG52
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101161407
gene id: 8090:LOC101161407
uniprot id: A0A3P9L837
uniprot id: H2LZI4
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8090:gabarap
gene id: 8090:gabarap
uniprot id: A0A3P9HG37
names: Similarity
messages: Belongs to the ATG8 family.

8090:luc7l3
gene id: 8090:luc7l3
uniprot id: H2M4I2
names: Similarity
messages: Belongs to the Luc7 family.

8090:tm4sf5
gene id: 8090:tm4sf5
uniprot id: A0A3P9H9V9
uniprot id: H2LSE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8090:LOC101158267
gene id: 8090:LOC101158267
uniprot id: H2MQP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:dtd1
gene id: 8090:dtd1
uniprot id: H2LAW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

8090:kdm7a
gene id: 8090:kdm7a
uniprot id: H2MMM1
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8090:tub
gene id: 8090:tub
uniprot id: A0A3P9KQK7
uniprot id: H2LR96
uniprot id: H2LR99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

8090:pcmtd1
gene id: 8090:pcmtd1
uniprot id: A0A3P9J3R6
uniprot id: H2MSX6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8090:popdc3
gene id: 8090:popdc3
uniprot id: H2MZF5
names: Similarity
messages: Belongs to the popeye family.

8090:LOC101160181
gene id: 8090:LOC101160181
uniprot id: H2MK97
names: Similarity
messages: Belongs to the SPIN/STSY family.

8090:dnmt3a
gene id: 8090:dnmt3a
uniprot id: A0A3B3H694
uniprot id: A0A3P9MHR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

8090:tut1
gene id: 8090:tut1
uniprot id: H2LHH7
names: Subcellular Location Annotation
messages: nucleolus

8090:prkg1
gene id: 8090:prkg1
uniprot id: A0A3B3HD67
uniprot id: A0A3P9KE39
uniprot id: Q75PY4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8090:lamtor3
gene id: 8090:lamtor3
uniprot id: A0A3P9M3T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

8090:LOC101172934
gene id: 8090:LOC101172934
uniprot id: A0A3P9KD05
names: Similarity
messages: Belongs to the ubiquitin family.

8090:LOC101157977
gene id: 8090:LOC101157977
uniprot id: H2M5E1
uniprot id: H2M5E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8090:natd1
gene id: 8090:natd1
uniprot id: A0A3B3H3N2
uniprot id: A0A3P9H3L4
names: Similarity
messages: Belongs to the NATD1 family.

8090:arl6ip5
gene id: 8090:arl6ip5
uniprot id: A0A3B3ICS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8090:ncbp1
gene id: 8090:ncbp1
uniprot id: A0A3B3H462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

8090:srp14
gene id: 8090:srp14
uniprot id: A0A3P9LQI7
uniprot id: H2MRF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

8090:elovl6
gene id: 8090:elovl6
uniprot id: A0A3B3HYM8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

8090:LOC101169735
gene id: 8090:LOC101169735
uniprot id: H2MUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

8090:olklklp
gene id: 8090:olklklp
uniprot id: Q2Z1R4
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101170447
gene id: 8090:LOC101170447
uniprot id: H2LVM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARM1 family.
messages: axon

8090:LOC101161547
gene id: 8090:LOC101161547
uniprot id: H2LA77
names: Subcellular Location Annotation
messages: cytoskeleton

8090:nft-vtr
gene id: 8090:nft-vtr
uniprot id: H1ADE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:LOC101169451
gene id: 8090:LOC101169451
uniprot id: A0A3P9LNV1
uniprot id: H2L7R5
names: Similarity
messages: Belongs to the TMEM106 family.

8090:uchl3
gene id: 8090:uchl3
uniprot id: A0A3P9JIJ3
names: Similarity
messages: Belongs to the peptidase C12 family.

8090:rbbp4
gene id: 8090:rbbp4
uniprot id: A0A3P9K167
uniprot id: H2MRV9
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101175278
gene id: 8090:LOC101175278
uniprot id: A0A3P9L185
uniprot id: H2MUL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

8090:LOC100049444
gene id: 8090:LOC100049444
uniprot id: A0A3B3HNF4
uniprot id: A0A3P9KGQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8090:foxp2
gene id: 8090:foxp2
uniprot id: B1NY82
names: Subcellular Location Annotation
messages: Nucleus

8090:tgfb1i1
gene id: 8090:tgfb1i1
uniprot id: A0A3B3H3L2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.
messages: Nucleus matrix
messages: The LD (leucine and aspartate-rich) motif 3 mediates interaction with GIT1 and functions as a nuclear export signal.
messages: cytoskeleton
messages: focal adhesion

8090:dnaja2
gene id: 8090:dnaja2
uniprot id: H2MJP9
names: Subcellular Location Annotation
messages: Membrane

8090:sybu
gene id: 8090:sybu
uniprot id: H2N2E3
uniprot id: H2N2E5
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101163345
gene id: 8090:LOC101163345
uniprot id: A0A3B3HXW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8090:rars2
gene id: 8090:rars2
uniprot id: H2M771
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8090:gng3
gene id: 8090:gng3
uniprot id: A0A3B3HTM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8090:dnttip2
gene id: 8090:dnttip2
uniprot id: H2MRM3
names: Subcellular Location Annotation
messages: nucleolus

8090:mrpl14
gene id: 8090:mrpl14
uniprot id: A0A3P9MEG9
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

8090:anp32a
gene id: 8090:anp32a
uniprot id: A0A3P9LKM1
uniprot id: H2L900
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

8090:LOC101174057
gene id: 8090:LOC101174057
uniprot id: H2MDV5
names: Similarity
messages: Belongs to the RBR family.

8090:fam69b
gene id: 8090:fam69b
uniprot id: H2LF19
names: Similarity
messages: Belongs to the DIPK family.

8090:p3h1
gene id: 8090:p3h1
uniprot id: H2MB16
names: Similarity
messages: Belongs to the leprecan family.

8090:LOC101171807
gene id: 8090:LOC101171807
uniprot id: H2L2X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

8090:pou3f1
gene id: 8090:pou3f1
uniprot id: A0A3P9LAI9
uniprot id: H2MIF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

8090:LOC101157966
gene id: 8090:LOC101157966
uniprot id: H2LS63
names: Subcellular Location Annotation
messages: Secreted

8090:plpp1
gene id: 8090:plpp1
uniprot id: H2LLG8
uniprot id: H2LLH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8090:lrrn1
gene id: 8090:lrrn1
uniprot id: H2MI08
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101174594
gene id: 8090:LOC101174594
uniprot id: H2MIG4
names: Similarity
messages: Belongs to the TPD52 family.

8090:clpp
gene id: 8090:clpp
uniprot id: H2MSC2
names: Similarity
messages: Belongs to the peptidase S14 family.

8090:LOC101175584
gene id: 8090:LOC101175584
uniprot id: H2LEL5
names: Similarity
messages: Belongs to the FRAS1 family.

8090:gnb3
gene id: 8090:gnb3
uniprot id: H2MBG0
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8090:cldn19
gene id: 8090:cldn19
uniprot id: A0A3B3IET2
uniprot id: A0A3P9JMG2
uniprot id: A0A3P9JZ42
uniprot id: H2MAI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8090:ube2i
gene id: 8090:ube2i
uniprot id: A0A3B3IMZ8
uniprot id: A0A3P9M3G0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:tmtops1b
gene id: 8090:tmtops1b
uniprot id: R9R6L1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:eif1ad
gene id: 8090:eif1ad
uniprot id: H2M116
names: Similarity
messages: Belongs to the EIF1AD family.

8090:LOC101174651
gene id: 8090:LOC101174651
uniprot id: Q92087
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
messages: Membrane

8090:serpini1
gene id: 8090:serpini1
uniprot id: H2MAD9
names: Similarity
messages: Belongs to the serpin family.

8090:hspa14
gene id: 8090:hspa14
uniprot id: H2MB65
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8090:ca5a
gene id: 8090:ca5a
uniprot id: A0A3P9LA65
uniprot id: H2MB56
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8090:LOC101171261
gene id: 8090:LOC101171261
uniprot id: A0A3B3IGR7
uniprot id: A0A3P9KZD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8090:cygb
gene id: 8090:cygb
uniprot id: Q575S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the globin family.
messages: Cytoplasm
messages: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.

8090:LOC101155688
gene id: 8090:LOC101155688
uniprot id: A0A3P9KN12
uniprot id: H2MKX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

8090:get4
gene id: 8090:get4
uniprot id: A1Z3X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Similarly, the bag6/bat3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The bag6/bat3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.
messages: Belongs to the GET4 family.
messages: Component of the bag6/bat3 complex.
messages: cytosol

8090:slc6a20
gene id: 8090:slc6a20
uniprot id: H2LEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:atg3
gene id: 8090:atg3
uniprot id: A0A3P9JJ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

8090:LOC101168821
gene id: 8090:LOC101168821
uniprot id: H2LM35
names: Similarity
messages: Belongs to the TACO1 family.

8090:prpf4b
gene id: 8090:prpf4b
uniprot id: H2MAX4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

8090:amigo1
gene id: 8090:amigo1
uniprot id: A0A3B3ICZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

8090:LOC101168579
gene id: 8090:LOC101168579
uniprot id: A0A3B3HQT5
names: Similarity
messages: Belongs to the RUNDC3 family.

8090:ispd
gene id: 8090:ispd
uniprot id: H2MQ93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

8090:sec13
gene id: 8090:sec13
uniprot id: A0A3P9IUY6
uniprot id: H2N090
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

8090:LOC101163759
gene id: 8090:LOC101163759
uniprot id: H2L9J7
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101167693
gene id: 8090:LOC101167693
uniprot id: H2N2N9
names: Subcellular Location Annotation
messages: Membrane

8090:LOC100533514
gene id: 8090:LOC100533514
uniprot id: E3WET8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8090:LOC101173165
gene id: 8090:LOC101173165
uniprot id: A0A3B3I669
uniprot id: A0A3P9JXG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

8090:LOC101158539
gene id: 8090:LOC101158539
uniprot id: H2M0H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

8090:LOC101157653
gene id: 8090:LOC101157653
uniprot id: A0A3B3HBI5
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101168172
gene id: 8090:LOC101168172
uniprot id: H2MXS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:LOC101164575
gene id: 8090:LOC101164575
uniprot id: H2LMH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101156698
gene id: 8090:LOC101156698
uniprot id: A0A3B3I453
names: Similarity
messages: Belongs to the taxilin family.

8090:LOC101164783
gene id: 8090:LOC101164783
uniprot id: H2LLA9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8090:dnajc24
gene id: 8090:dnajc24
uniprot id: H2L5G9
names: Similarity
messages: Belongs to the DPH4 family.

8090:LOC101163579
gene id: 8090:LOC101163579
uniprot id: H2MPR3
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.

8090:ret
gene id: 8090:ret
uniprot id: H2MFY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.

8090:LOC101155832
gene id: 8090:LOC101155832
uniprot id: A0A3P9JTN5
uniprot id: H2L9A5
names: Similarity
messages: Belongs to the actin family.

8090:LOC101165175
gene id: 8090:LOC101165175
uniprot id: H2MLX0
names: Similarity
messages: Belongs to the peptidase C1 family.

8090:cops9
gene id: 8090:cops9
uniprot id: A0A3B3HSK5
uniprot id: A0A3P9K247
names: Similarity
messages: Belongs to the CSN9 family.

8090:nsd3
gene id: 8090:nsd3
uniprot id: H2LC66
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:rundc3b
gene id: 8090:rundc3b
uniprot id: A0A3B3IJ96
names: Similarity
messages: Belongs to the RUNDC3 family.

8090:ints8
gene id: 8090:ints8
uniprot id: H2LUR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

8090:tmem170a
gene id: 8090:tmem170a
uniprot id: A0A3B3HR43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

8090:LOC101161875
gene id: 8090:LOC101161875
uniprot id: A0A3B3HLR0
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101164258
gene id: 8090:LOC101164258
uniprot id: H2LBE2
uniprot id: H2LBE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

8090:prickle3
gene id: 8090:prickle3
uniprot id: A0A3B3I8N2
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

8090:ddx3x
gene id: 8090:ddx3x
uniprot id: A0A3B3H7V9
uniprot id: A0A3B3H7X1
uniprot id: A0A3B3H9G3
uniprot id: A0A3B3HDW4
uniprot id: A0A3B3HE49
uniprot id: A0A3B3HWR3
names: Similarity
messages: Belongs to the DEAD box helicase family.

8090:xrn2
gene id: 8090:xrn2
uniprot id: H2MS13
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

8090:insig1
gene id: 8090:insig1
uniprot id: A0A3B3HNW2
uniprot id: A0A3P9M4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

8090:LOC101157407
gene id: 8090:LOC101157407
uniprot id: A0A3B3IKK9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:LOC101164925
gene id: 8090:LOC101164925
uniprot id: H2M9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8090:hpx
gene id: 8090:hpx
uniprot id: Q8JIP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

8090:tctn1
gene id: 8090:tctn1
uniprot id: A0A3B3I6Z2
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

8090:LOC101168710
gene id: 8090:LOC101168710
uniprot id: H2MFS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:tmem161a
gene id: 8090:tmem161a
uniprot id: A0A3B3HBU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

8090:LOC101161022
gene id: 8090:LOC101161022
uniprot id: A0A3P9LLG6
uniprot id: H2M298
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

8090:slc30a8
gene id: 8090:slc30a8
uniprot id: A0A3B3IKY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8090:casp3
gene id: 8090:casp3
uniprot id: A0A3P9LGK4
uniprot id: Q8JIS8
names: Similarity
messages: Belongs to the peptidase C14A family.

8090:gja5
gene id: 8090:gja5
uniprot id: H2MUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:pus3
gene id: 8090:pus3
uniprot id: H2LWW2
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8090:LOC101159282
gene id: 8090:LOC101159282
uniprot id: H2LH70
names: Subcellular Location Annotation
messages: Mitochondrion

8090:hspe1
gene id: 8090:hspe1
uniprot id: Q9W6X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein.
messages: Homoheptamer arranged in a ring structure. 2 heptameric Hsp10 rings interact with a Hsp60 tetradecamer in the structure of a back-to-back double heptameric ring to form the symmetrical football complex.
messages: Mitochondrion matrix

8090:LOC101160075
gene id: 8090:LOC101160075
uniprot id: H2MJS4
names: Similarity
messages: Belongs to the DEAD box helicase family.

8090:LOC101170278
gene id: 8090:LOC101170278
uniprot id: H2L9T2
names: Similarity
messages: Belongs to the peptidase S1B family.

8090:apoo
gene id: 8090:apoo
uniprot id: H2LBS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

8090:LOC101160005
gene id: 8090:LOC101160005
uniprot id: A0A3B3HAU0
names: Similarity
messages: Belongs to the peptidase C1 family.

8090:pcna
gene id: 8090:pcna
uniprot id: A0A3P9I149
uniprot id: H2LCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

8090:myadml2
gene id: 8090:myadml2
uniprot id: H2LUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

8090:LOC101161642
gene id: 8090:LOC101161642
uniprot id: A0A3B3HBB0
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8090:tpx2
gene id: 8090:tpx2
uniprot id: H2MX85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: spindle

8090:epha5
gene id: 8090:epha5
uniprot id: H2M8D3
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101165916
gene id: 8090:LOC101165916
uniprot id: A0A3B3IJ04
names: Similarity
messages: Belongs to the Bcl-2 family.

8090:LOC101161175
gene id: 8090:LOC101161175
uniprot id: A0A3B3H3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8090:LOC101169085
gene id: 8090:LOC101169085
uniprot id: A0A3B3H7S5
uniprot id: H2MYQ2
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

8090:dus4l
gene id: 8090:dus4l
uniprot id: A0A3B3I1V8
uniprot id: H2LWD2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

8090:LOC101173029
gene id: 8090:LOC101173029
uniprot id: H2MC64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8090:samd4a
gene id: 8090:samd4a
uniprot id: A0A3B3IJ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

8090:map3k13
gene id: 8090:map3k13
uniprot id: A0A3B3HM29
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8090:evx1
gene id: 8090:evx1
uniprot id: Q2WFV6
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101163746
gene id: 8090:LOC101163746
uniprot id: H2MHL1
names: Subcellular Location Annotation
messages: Membrane

8090:slc28a1
gene id: 8090:slc28a1
uniprot id: H2LVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

8090:limk2
gene id: 8090:limk2
uniprot id: A0A3P9IV21
uniprot id: H2LR90
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8090:LOC101166747
gene id: 8090:LOC101166747
uniprot id: A0A3B3I3D3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8090:vasp
gene id: 8090:vasp
uniprot id: H2MDI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

8090:ldah
gene id: 8090:ldah
uniprot id: A0A3B3H4X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

8090:rin2
gene id: 8090:rin2
uniprot id: A0A3B3HHD3
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

8090:prpf38b
gene id: 8090:prpf38b
uniprot id: H2MLH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

8090:rps23
gene id: 8090:rps23
uniprot id: A0A3P9H6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Rough endoplasmic reticulum

8090:pop5
gene id: 8090:pop5
uniprot id: H2MIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

8090:nanos1a
gene id: 8090:nanos1a
uniprot id: A7XBY2
names: Similarity
messages: Belongs to the nanos family.

8090:fgf19
gene id: 8090:fgf19
uniprot id: H2L3M7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8090:erlec1
gene id: 8090:erlec1
uniprot id: H2M590
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum lumen
messages: Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation.

8090:LOC101165956
gene id: 8090:LOC101165956
uniprot id: H2MVT8
names: Subcellular Location Annotation
messages: Membrane

8090:npr2
gene id: 8090:npr2
uniprot id: O42440
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8090:LOC101161616
gene id: 8090:LOC101161616
uniprot id: H2L6E3
names: Subcellular Location Annotation
messages: Membrane

8090:scoc
gene id: 8090:scoc
uniprot id: A0A3P9MA59
uniprot id: H2L9H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

8090:LOC101172670
gene id: 8090:LOC101172670
uniprot id: H2MHI0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8090:LOC101155486
gene id: 8090:LOC101155486
uniprot id: A0A3B3H4R9
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101173540
gene id: 8090:LOC101173540
uniprot id: H2LX26
names: Subcellular Location Annotation
messages: Membrane

8090:pskh1
gene id: 8090:pskh1
uniprot id: A0A3P9MHQ7
uniprot id: H2MBV3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:LOC101167322
gene id: 8090:LOC101167322
uniprot id: A0A3B3HTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8090:sult1a4
gene id: 8090:sult1a4
uniprot id: H2LNB2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:rock1
gene id: 8090:rock1
uniprot id: A0A3B3INV7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

8090:LOC101169057
gene id: 8090:LOC101169057
uniprot id: H2MLU2
uniprot id: H2MLU4
names: Similarity
messages: Belongs to the calponin family.

8090:hcrt
gene id: 8090:hcrt
uniprot id: H2LFX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: Synapse
messages: Vesicle

8090:chpt1
gene id: 8090:chpt1
uniprot id: A0A3P9KT19
uniprot id: H2MLS2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8090:vps54
gene id: 8090:vps54
uniprot id: A0A3B3HYW5
uniprot id: A0A3B3I7W2
names: Similarity
messages: Belongs to the VPS54 family.

8090:LOC101162596
gene id: 8090:LOC101162596
uniprot id: H2L707
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

8090:mmyhl2
gene id: 8090:mmyhl2
uniprot id: C4TIP3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8090:LOC101171516
gene id: 8090:LOC101171516
uniprot id: A0A3P9HMI5
uniprot id: B6F103
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101171914
gene id: 8090:LOC101171914
uniprot id: H2L3T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

8090:LOC101166477
gene id: 8090:LOC101166477
uniprot id: A0A3B3I040
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8090:slc1a5
gene id: 8090:slc1a5
uniprot id: H2LRW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8090:dlgap5
gene id: 8090:dlgap5
uniprot id: H2LEA9
names: Similarity
messages: Belongs to the SAPAP family.

8090:LOC101158780
gene id: 8090:LOC101158780
uniprot id: H2LC90
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8090:nfrkb
gene id: 8090:nfrkb
uniprot id: H2LP97
names: Subcellular Location Annotation
messages: Nucleus

8090:mpc2
gene id: 8090:mpc2
uniprot id: A0A3P9JCD2
uniprot id: H2MBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

8090:cdh22
gene id: 8090:cdh22
uniprot id: H2LNS0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8090:pdk3
gene id: 8090:pdk3
uniprot id: H2LTP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

8090:slc2a4
gene id: 8090:slc2a4
uniprot id: A0A3P9KLU3
uniprot id: H2LPI9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8090:cdk5rap3
gene id: 8090:cdk5rap3
uniprot id: A0A3B3INQ8
names: Similarity
messages: Belongs to the CDK5RAP3 family.

8090:thg1l
gene id: 8090:thg1l
uniprot id: A0A3P9HCY1
uniprot id: H2LT86
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

8090:LOC101163934
gene id: 8090:LOC101163934
uniprot id: A0A3P9KW25
uniprot id: H2LZM2
names: Similarity
messages: Belongs to the cystatin family.

8090:LOC101160521
gene id: 8090:LOC101160521
uniprot id: H2MVD9
names: Similarity
messages: Belongs to the intermediate filament family.

8090:ddx24
gene id: 8090:ddx24
uniprot id: H2LID7
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8090:prpf18
gene id: 8090:prpf18
uniprot id: A0A3P9LM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

8090:pptc7
gene id: 8090:pptc7
uniprot id: A0A3P9J781
uniprot id: H2MMK7
names: Similarity
messages: Belongs to the PP2C family.

8090:cyr61
gene id: 8090:cyr61
uniprot id: A0A3P9KJT7
uniprot id: H2M4W8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101159195
gene id: 8090:LOC101159195
uniprot id: H2LQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

8090:LOC101163895
gene id: 8090:LOC101163895
uniprot id: A0A3B3HGT1
uniprot id: A0A3P9JNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:irx3
gene id: 8090:irx3
uniprot id: A0A3P9LGB0
uniprot id: H2MF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8090:lrig2
gene id: 8090:lrig2
uniprot id: H2LTP4
names: Subcellular Location Annotation
messages: Membrane

8090:mtmr2
gene id: 8090:mtmr2
uniprot id: A0A3B3I714
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8090:ism1
gene id: 8090:ism1
uniprot id: H2M9C9
names: Similarity
messages: Belongs to the isthmin family.

8090:LOC101165994
gene id: 8090:LOC101165994
uniprot id: H2LUV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:runx2
gene id: 8090:runx2
uniprot id: A0A3P9I1Z3
uniprot id: A0A3P9I236
uniprot id: H2M2V2
uniprot id: Q9DEF2
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101162456
gene id: 8090:LOC101162456
uniprot id: H2LDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC101173727
gene id: 8090:LOC101173727
uniprot id: A0A3B3I8H4
uniprot id: H2MFQ7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

8090:snx33
gene id: 8090:snx33
uniprot id: H2L8T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8090:LOC101174792
gene id: 8090:LOC101174792
uniprot id: A0A3B3H445
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101170017
gene id: 8090:LOC101170017
uniprot id: A0A3B3H8B8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:LOC100125506
gene id: 8090:LOC100125506
uniprot id: A0A3P9H087
uniprot id: H2LRW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

8090:LOC101155171
gene id: 8090:LOC101155171
uniprot id: H2L974
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

8090:ntf3
gene id: 8090:ntf3
uniprot id: A0A3B3HXF0
uniprot id: A0A3P9IQW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

8090:arl4c
gene id: 8090:arl4c
uniprot id: A0A3P9HMR8
uniprot id: H2MFI0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8090:LOC101172286
gene id: 8090:LOC101172286
uniprot id: A0A3P9M1C3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC101159406
gene id: 8090:LOC101159406
uniprot id: A0A3B3H7D7
uniprot id: A0A3B3HZD7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:hoxc13
gene id: 8090:hoxc13
uniprot id: A0A3P9IMJ0
uniprot id: Q3V600
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8090:LOC101156117
gene id: 8090:LOC101156117
uniprot id: A0A3B3HBB6
uniprot id: H2MM96
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101165682
gene id: 8090:LOC101165682
uniprot id: H2MQD3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8090:egr2
gene id: 8090:egr2
uniprot id: H2MI30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

8090:LOC101170520
gene id: 8090:LOC101170520
uniprot id: Q2WFU0
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101169626
gene id: 8090:LOC101169626
uniprot id: A0A3P9KDL2
uniprot id: H2MB09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

8090:LOC101168038
gene id: 8090:LOC101168038
uniprot id: A0A3B3IBJ8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:maf1
gene id: 8090:maf1
uniprot id: A0A3P9KL28
uniprot id: H2M558
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

8090:timm8b
gene id: 8090:timm8b
uniprot id: A0A3B3HF56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8090:LOC101162795
gene id: 8090:LOC101162795
uniprot id: A0A3B3HSE3
uniprot id: A0A3P9KBY1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:LOC101163175
gene id: 8090:LOC101163175
uniprot id: A0A3P9IP69
uniprot id: H2LYW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8090:LOC101173447
gene id: 8090:LOC101173447
uniprot id: A0A3P9JY72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

8090:rnf182
gene id: 8090:rnf182
uniprot id: A0A3B3I130
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

8090:agl
gene id: 8090:agl
uniprot id: H2LLD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

8090:LOC101157940
gene id: 8090:LOC101157940
uniprot id: A0A3B3HR25
uniprot id: H2LVH6
names: Subcellular Location Annotation
messages: Membrane

8090:c9h12orf49
gene id: 8090:c9h12orf49
uniprot id: A0A3P9KMZ3
uniprot id: H2L5S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101170552
gene id: 8090:LOC101170552
uniprot id: A0A3B3IJ64
names: Similarity
messages: Belongs to the peptidase C48 family.

8090:pfdn5
gene id: 8090:pfdn5
uniprot id: A0A3P9K5K2
uniprot id: H2L8N4
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

8090:LOC101156393
gene id: 8090:LOC101156393
uniprot id: A0A3B3I2E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

8090:LOC101174659
gene id: 8090:LOC101174659
uniprot id: A0A3B3HZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

8090:trpv1
gene id: 8090:trpv1
uniprot id: H2M7B2
names: Subcellular Location Annotation
messages: Membrane

8090:KEF90 p07
gene id: 8090:KEF90_p07
uniprot id: Q8HLW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

8090:eif3j
gene id: 8090:eif3j
uniprot id: H2LP66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8090:LOC101161416
gene id: 8090:LOC101161416
uniprot id: A0A3P9I126
uniprot id: H2M0Z2
names: Similarity
messages: Belongs to the peptidase C1 family.

8090:LOC101158220
gene id: 8090:LOC101158220
uniprot id: A0A3B3I4U6
names: Similarity
messages: Belongs to the peptidase C2 family.

8090:trappc4
gene id: 8090:trappc4
uniprot id: A0A3P9JPC3
uniprot id: H2MCX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

8090:LOC101169900
gene id: 8090:LOC101169900
uniprot id: A0A3B3HVN5
names: Similarity
messages: Belongs to the SPT2 family.

8090:rhbdl3
gene id: 8090:rhbdl3
uniprot id: A0A3B3I658
uniprot id: A0A3P9HKD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

8090:pik3c2g
gene id: 8090:pik3c2g
uniprot id: A0A3B3H7C6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8090:nkx2-1
gene id: 8090:nkx2-1
uniprot id: A0A3B3I233
names: Subcellular Location Annotation
messages: Nucleus

8090:xk
gene id: 8090:xk
uniprot id: A0A3B3HUY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8090:lpl
gene id: 8090:lpl
uniprot id: H3K3W5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

8090:LOC101173508
gene id: 8090:LOC101173508
uniprot id: A0A3B3IBR9
names: Subcellular Location Annotation
messages: Nucleus

8090:npb
gene id: 8090:npb
uniprot id: A0A3P9HN07
uniprot id: H2M9F7
uniprot id: W8VTS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

8090:itgb8
gene id: 8090:itgb8
uniprot id: H2LG92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

8090:tmem18
gene id: 8090:tmem18
uniprot id: H2MFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

8090:LOC101175010
gene id: 8090:LOC101175010
uniprot id: H2LSI6
names: Subcellular Location Annotation
messages: ruffle membrane

8090:kcnd1
gene id: 8090:kcnd1
uniprot id: A0A3P9I1V4
uniprot id: H2MVV2
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8090:lrfn5
gene id: 8090:lrfn5
uniprot id: A0A3B3H8H9
names: Subcellular Location Annotation
messages: Membrane

8090:cntn1
gene id: 8090:cntn1
uniprot id: A0A3B3IBC9
uniprot id: H2LDU8
names: Subcellular Location Annotation
messages: Membrane

8090:kcnh8
gene id: 8090:kcnh8
uniprot id: H2LIZ2
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8090:chek1
gene id: 8090:chek1
uniprot id: H2LMC8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

8090:ace
gene id: 8090:ace
uniprot id: A0A3B3IKM3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

8090:cactin
gene id: 8090:cactin
uniprot id: H2MJC0
names: Similarity
messages: Belongs to the CACTIN family.

8090:unc119
gene id: 8090:unc119
uniprot id: A0A3B3HI02
uniprot id: A0A3P9IRB4
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8090:LOC101163079
gene id: 8090:LOC101163079
uniprot id: H2LQW7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101161581
gene id: 8090:LOC101161581
uniprot id: A0A3P9J5A8
uniprot id: H2LX52
names: Subcellular Location Annotation
messages: Nucleus

8090:slc52a3
gene id: 8090:slc52a3
uniprot id: H2MJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8090:tbx2
gene id: 8090:tbx2
uniprot id: H2MIQ8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8090:LOC101157705
gene id: 8090:LOC101157705
uniprot id: H2M9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101161846
gene id: 8090:LOC101161846
uniprot id: H2MT52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8090:slc25a26
gene id: 8090:slc25a26
uniprot id: A0A3B3HBJ1
uniprot id: A0A3P9IYM2
uniprot id: H2LVG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:kcnk10
gene id: 8090:kcnk10
uniprot id: H2MCD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8090:cxxc4
gene id: 8090:cxxc4
uniprot id: A0A3B3H5H7
uniprot id: A0A3P9IJP5
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101175232
gene id: 8090:LOC101175232
uniprot id: A0A3P9IV50
uniprot id: H2LYI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8090:pdia6
gene id: 8090:pdia6
uniprot id: A0A3B3IJK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

8090:LOC101168248
gene id: 8090:LOC101168248
uniprot id: H2LVI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:glb1l2
gene id: 8090:glb1l2
uniprot id: H2MI16
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

8090:cfap36
gene id: 8090:cfap36
uniprot id: H2LHP7
uniprot id: H2LHQ1
names: Similarity
messages: Belongs to the CFAP36 family.

8090:LOC101170291
gene id: 8090:LOC101170291
uniprot id: A0A3P9LZL9
uniprot id: H2LMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8090:rab27b
gene id: 8090:rab27b
uniprot id: A0A3B3HWT5
uniprot id: A0A3P9I491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8090:LOC101174040
gene id: 8090:LOC101174040
uniprot id: A0A3P9MKF5
uniprot id: H2L8X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8090:LOC101159301
gene id: 8090:LOC101159301
uniprot id: A0A3B3IPX4
uniprot id: H2LHY7
uniprot id: H2LHY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8090:LOC101172729
gene id: 8090:LOC101172729
uniprot id: A0A3B3I301
uniprot id: A0A3P9KP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8090:LOC101163641
gene id: 8090:LOC101163641
uniprot id: A0A3B3H2U1
names: Similarity
messages: Belongs to the heme oxygenase family.

8090:LOC101175628
gene id: 8090:LOC101175628
uniprot id: A0A3P9MJ66
uniprot id: H2MIQ5
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

8090:LOC101157773
gene id: 8090:LOC101157773
uniprot id: H2LIM7
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101159911
gene id: 8090:LOC101159911
uniprot id: H2L663
uniprot id: H2L664
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

8090:fuca1
gene id: 8090:fuca1
uniprot id: H2MDA6
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

8090:st6galnac2
gene id: 8090:st6galnac2
uniprot id: H2MEW5
uniprot id: Q5K026
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:znrf3
gene id: 8090:znrf3
uniprot id: A0A3B3IJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

8090:LOC101162295
gene id: 8090:LOC101162295
uniprot id: A0A3P9K6F9
uniprot id: H2MKN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:serpinc1
gene id: 8090:serpinc1
uniprot id: H2MGA8
names: Similarity
messages: Belongs to the serpin family.

8090:LOC101170744
gene id: 8090:LOC101170744
uniprot id: H2LPZ8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:cep76
gene id: 8090:cep76
uniprot id: A0A3B3HN32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

8090:tnfrsf1a
gene id: 8090:tnfrsf1a
uniprot id: H2M9Z2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:cacul1
gene id: 8090:cacul1
uniprot id: H2MEY3
names: Similarity
messages: Belongs to the cullin family.

8090:LOC101165191
gene id: 8090:LOC101165191
uniprot id: H2MPW8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8090:LOC101164921
gene id: 8090:LOC101164921
uniprot id: A0A3B3I499
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

8090:ube3d
gene id: 8090:ube3d
uniprot id: H2L971
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

8090:LOC101168608
gene id: 8090:LOC101168608
uniprot id: A0A3B3HJN0
uniprot id: A0A3P9MB27
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

8090:LOC101156596
gene id: 8090:LOC101156596
uniprot id: H2LG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

8090:LOC101158262
gene id: 8090:LOC101158262
uniprot id: H2L2Z0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8090:LOC101162174
gene id: 8090:LOC101162174
uniprot id: A0A3B3IGX0
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101155208
gene id: 8090:LOC101155208
uniprot id: H2M1E2
names: Similarity
messages: Belongs to the CD36 family.

8090:LOC101173781
gene id: 8090:LOC101173781
uniprot id: A0A3P9K2G6
uniprot id: H2LXW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC100049520
gene id: 8090:LOC100049520
uniprot id: Q6DVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8090:LOC101159569
gene id: 8090:LOC101159569
uniprot id: H2LFF9
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101165892
gene id: 8090:LOC101165892
uniprot id: A0A3P9JJC6
uniprot id: H2L8L1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC105354861
gene id: 8090:LOC105354861
uniprot id: H2MFX6
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8090:cpsf2
gene id: 8090:cpsf2
uniprot id: A0A3P9HTL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

8090:LOC105358676
gene id: 8090:LOC105358676
uniprot id: O13116
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101167450
gene id: 8090:LOC101167450
uniprot id: A0A3B3H4U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8090:LOC101154874
gene id: 8090:LOC101154874
uniprot id: H2MTH6
uniprot id: H2MTH8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8090:crhbp
gene id: 8090:crhbp
uniprot id: H2LA63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

8090:mtfp1
gene id: 8090:mtfp1
uniprot id: H2LSP5
names: Similarity
messages: Belongs to the MTFP1 family.

8090:LOC101166512
gene id: 8090:LOC101166512
uniprot id: A0A3B3HES5
uniprot id: A0A3B3I773
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8090:dcp1b
gene id: 8090:dcp1b
uniprot id: H2MG19
names: Similarity
messages: Belongs to the DCP1 family.

8090:foxl1
gene id: 8090:foxl1
uniprot id: A9Q6B1
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101160592
gene id: 8090:LOC101160592
uniprot id: H2MP81
names: Similarity
messages: Belongs to the Bcl-2 family.

8090:gdf10
gene id: 8090:gdf10
uniprot id: H2N163
names: Similarity
messages: Belongs to the TGF-beta family.

8090:LOC101172688
gene id: 8090:LOC101172688
uniprot id: H2LTC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

8090:glyr1
gene id: 8090:glyr1
uniprot id: A0A3P9L5D2
uniprot id: A0A3P9L5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

8090:nfe2
gene id: 8090:nfe2
uniprot id: A0A3B3HZD2
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8090:LOC101174851
gene id: 8090:LOC101174851
uniprot id: H2LKH8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8090:selenok
gene id: 8090:selenok
uniprot id: A0A3P9L823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein K family.
messages: Endoplasmic reticulum membrane

8090:abl1
gene id: 8090:abl1
uniprot id: A0A3B3H733
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8090:LOC101157700
gene id: 8090:LOC101157700
uniprot id: H2LXF9
names: Similarity
messages: Belongs to the CDR2 family.

8090:pkp1
gene id: 8090:pkp1
uniprot id: H2LWI0
names: Similarity
messages: Belongs to the beta-catenin family.

8090:cd79b
gene id: 8090:cd79b
uniprot id: H2M7W6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:mrps11
gene id: 8090:mrps11
uniprot id: H2MHZ7
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

8090:tmeff1
gene id: 8090:tmeff1
uniprot id: H2LQE9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC105353814
gene id: 8090:LOC105353814
uniprot id: A0A3B3HRF0
names: Similarity
messages: Belongs to the CCSER family.

8090:ndc1
gene id: 8090:ndc1
uniprot id: H2N2B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

8090:slc16a7
gene id: 8090:slc16a7
uniprot id: H2LZ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8090:adam10
gene id: 8090:adam10
uniprot id: H2LW33
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101166725
gene id: 8090:LOC101166725
uniprot id: H2L868
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8090:LOC101167480
gene id: 8090:LOC101167480
uniprot id: A0A3B3I4P9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:itga8
gene id: 8090:itga8
uniprot id: H2LWH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8090:arpc2
gene id: 8090:arpc2
uniprot id: A0A3P9HU65
uniprot id: H2LQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

8090:mov10
gene id: 8090:mov10
uniprot id: H2LVN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

8090:LOC101169088
gene id: 8090:LOC101169088
uniprot id: A0A3B3HLA7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8090:gstz1
gene id: 8090:gstz1
uniprot id: A0A3B3HPX3
uniprot id: H2MNW6
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

8090:LOC101174987
gene id: 8090:LOC101174987
uniprot id: H2MKK1
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155598
gene id: 8090:LOC101155598
uniprot id: H2MME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

8090:gpr180
gene id: 8090:gpr180
uniprot id: A0A3B3ICM2
names: Subcellular Location Annotation
messages: Membrane

8090:zufsp
gene id: 8090:zufsp
uniprot id: H2LB59
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

8090:ccdc94
gene id: 8090:ccdc94
uniprot id: H2MH03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

8090:LOC101156124
gene id: 8090:LOC101156124
uniprot id: H2LNB9
names: Similarity
messages: Belongs to the WD repeat coronin family.

8090:coro2b
gene id: 8090:coro2b
uniprot id: H2L8W9
uniprot id: H2L8X0
names: Similarity
messages: Belongs to the WD repeat coronin family.

8090:LOC101175554
gene id: 8090:LOC101175554
uniprot id: A0A3B3HLK1
uniprot id: A0A3P9KGL1
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8090:homez
gene id: 8090:homez
uniprot id: H2M9V1
names: Subcellular Location Annotation
messages: Nucleus

8090:tacr1a
gene id: 8090:tacr1a
uniprot id: H2MMY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:popdc2
gene id: 8090:popdc2
uniprot id: H2LXG3
uniprot id: H2LXG4
names: Similarity
messages: Belongs to the popeye family.

8090:gbx1
gene id: 8090:gbx1
uniprot id: A0A3P9HIU5
uniprot id: H2MT21
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101170279
gene id: 8090:LOC101170279
uniprot id: H2LTG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:cntn2
gene id: 8090:cntn2
uniprot id: H2M472
names: Subcellular Location Annotation
messages: Membrane

8090:stk40
gene id: 8090:stk40
uniprot id: A0A3P9MK84
uniprot id: H2MHS9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

8090:rps27a
gene id: 8090:rps27a
uniprot id: A0A3B3IL47
uniprot id: A0A3P9H5J3
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

8090:pigl
gene id: 8090:pigl
uniprot id: A0A3B3I3G9
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

8090:rfc4
gene id: 8090:rfc4
uniprot id: A0A3B3H3F4
names: Similarity
messages: Belongs to the activator 1 small subunits family.

8090:LOC101164920
gene id: 8090:LOC101164920
uniprot id: A0A3B3IPH5
uniprot id: A0A3P9HW81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

8090:thumpd3
gene id: 8090:thumpd3
uniprot id: H2L4X7
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8090:dhx29
gene id: 8090:dhx29
uniprot id: A0A3B3IA42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

8090:unc5a
gene id: 8090:unc5a
uniprot id: A0A3B3IBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8090:ciapin1
gene id: 8090:ciapin1
uniprot id: H2MJQ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

8090:mtch2
gene id: 8090:mtch2
uniprot id: H2L3D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:nck2
gene id: 8090:nck2
uniprot id: A0A3B3HK22
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

8090:entpd4
gene id: 8090:entpd4
uniprot id: A0A3B3HKL7
uniprot id: H2M5E6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8090:LOC101159907
gene id: 8090:LOC101159907
uniprot id: A0A3B3IJN3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:LOC101156470
gene id: 8090:LOC101156470
uniprot id: H2MJA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8090:letmd1
gene id: 8090:letmd1
uniprot id: H2MK91
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

8090:clip1
gene id: 8090:clip1
uniprot id: A0A3B3H480
uniprot id: A0A3B3HXY2
uniprot id: A0A3B3IEW9
names: Subcellular Location Annotation
messages: cytoskeleton

8090:tsnax
gene id: 8090:tsnax
uniprot id: A0A3B3I534
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

8090:ppp4r3b
gene id: 8090:ppp4r3b
uniprot id: A0A3B3HX16
names: Similarity
messages: Belongs to the SMEK family.

8090:LOC101171790
gene id: 8090:LOC101171790
uniprot id: H2MR87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8090:lhx8
gene id: 8090:lhx8
uniprot id: H2LGA3
names: Subcellular Location Annotation
messages: Nucleus

8090:tmem129
gene id: 8090:tmem129
uniprot id: H2N267
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

8090:lbx1
gene id: 8090:lbx1
uniprot id: A0A3P9LRA5
uniprot id: H2MBK2
names: Subcellular Location Annotation
messages: Nucleus

8090:cyp26a1
gene id: 8090:cyp26a1
uniprot id: A0A3P9L441
uniprot id: A5HKK8
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101155269
gene id: 8090:LOC101155269
uniprot id: H2MLG9
names: Similarity
messages: Belongs to the neuritin family.

8090:rprd2
gene id: 8090:rprd2
uniprot id: A0A3B3I671
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

8090:tmem163
gene id: 8090:tmem163
uniprot id: A0A3P9I7V5
uniprot id: H2LHG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

8090:gnmt
gene id: 8090:gnmt
uniprot id: A0A3B3H9X6
uniprot id: A0A3P9L7D3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

8090:LOC101165831
gene id: 8090:LOC101165831
uniprot id: A0A3B3IJN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8090:qpctl
gene id: 8090:qpctl
uniprot id: H2LQX6
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

8090:guf1
gene id: 8090:guf1
uniprot id: H2M0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

8090:mfsd10
gene id: 8090:mfsd10
uniprot id: H2L7Z8
names: Subcellular Location Annotation
messages: Membrane

8090:ciao1
gene id: 8090:ciao1
uniprot id: A0A3B3HXY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

8090:kif1bp
gene id: 8090:kif1bp
uniprot id: H2M2X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

8090:LOC101156256
gene id: 8090:LOC101156256
uniprot id: H2MB97
names: Similarity
messages: Belongs to the serpin family.

8090:cct4
gene id: 8090:cct4
uniprot id: A0A3B3H7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8090:rft1
gene id: 8090:rft1
uniprot id: A0A3B3H2P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

8090:LOC101163416
gene id: 8090:LOC101163416
uniprot id: H2LZ01
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101154833
gene id: 8090:LOC101154833
uniprot id: A0A3B3I250
names: Similarity
messages: Belongs to the HEBP family.

8090:rbm22
gene id: 8090:rbm22
uniprot id: A0A3P9JU52
uniprot id: H2LJT2
names: Similarity
messages: Belongs to the SLT11 family.

8090:LOC101169275
gene id: 8090:LOC101169275
uniprot id: H2L9L0
uniprot id: H2L9L3
names: Subcellular Location Annotation
messages: Nucleus

8090:chrdl2
gene id: 8090:chrdl2
uniprot id: H2LRQ5
names: Subcellular Location Annotation
messages: Secreted

8090:LOC100049292
gene id: 8090:LOC100049292
uniprot id: H2MJK8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:kdelr3
gene id: 8090:kdelr3
uniprot id: H2MI55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

8090:adgrd1
gene id: 8090:adgrd1
uniprot id: H2MFE0
names: Subcellular Location Annotation
messages: Membrane

8090:mut
gene id: 8090:mut
uniprot id: H2M2Q9
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

8090:hvcn1
gene id: 8090:hvcn1
uniprot id: H2N1J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

8090:sema4g
gene id: 8090:sema4g
uniprot id: H2M7H2
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:gabra5
gene id: 8090:gabra5
uniprot id: H2MMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:lin7c
gene id: 8090:lin7c
uniprot id: A0A3P9HWT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8090:imp4
gene id: 8090:imp4
uniprot id: A0A3P9HH15
uniprot id: H2MQ86
names: Subcellular Location Annotation
messages: nucleolus

8090:LOC101171335
gene id: 8090:LOC101171335
uniprot id: A0A3P9LGF5
uniprot id: H2MQF5
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

8090:grn
gene id: 8090:grn
uniprot id: H2MGH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8090:slc34a1
gene id: 8090:slc34a1
uniprot id: H2LJZ4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

8090:mrps10
gene id: 8090:mrps10
uniprot id: H2MIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

8090:kat8
gene id: 8090:kat8
uniprot id: A0A3B3HRN9
uniprot id: A0A3P9MFR9
uniprot id: H2L6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

8090:LOC101170837
gene id: 8090:LOC101170837
uniprot id: H2LJR6
names: Subcellular Location Annotation
messages: Membrane

8090:slc24a2
gene id: 8090:slc24a2
uniprot id: A0A3B3I178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

8090:fam149b1
gene id: 8090:fam149b1
uniprot id: A0A3B3I0B1
uniprot id: A0A3B3IHF2
names: Similarity
messages: Belongs to the FAM149 family.

8090:LOC101173249
gene id: 8090:LOC101173249
uniprot id: A0A3P9LTC4
uniprot id: H2MA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8090:LOC101163430
gene id: 8090:LOC101163430
uniprot id: H2L6E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

8090:idua
gene id: 8090:idua
uniprot id: A0A3B3ICX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

8090:yipf5
gene id: 8090:yipf5
uniprot id: H2L7Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

8090:azin1
gene id: 8090:azin1
uniprot id: H2LD33
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

8090:LOC101161523
gene id: 8090:LOC101161523
uniprot id: H2MCA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8090:LOC101158965
gene id: 8090:LOC101158965
uniprot id: H2LRL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8090:lgi3
gene id: 8090:lgi3
uniprot id: H2MGF9
names: Subcellular Location Annotation
messages: Secreted

8090:LOC101170217
gene id: 8090:LOC101170217
uniprot id: A0A3P9HFA2
uniprot id: A0A3P9KQR4
uniprot id: A0A3P9KR34
uniprot id: H2M0K6
uniprot id: H2M0L2
uniprot id: H2M0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

8090:tdrd1
gene id: 8090:tdrd1
uniprot id: A9CPT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the TDRD1 family.
messages: Cytoplasm
messages: Expressed in both the ovary and testis in the adult. Present in migrating primordial germ cells (PGCs) and also in the germ cells in both the gonadal primordia (stage 33), and in the developing ovary and testis.
messages: Interacts with MAEL. Interacts with PIWIL1, PIWIL2 and PIWIL4 (when methylated on arginine residues) (By similarity).
messages: Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins (By similarity).

8090:ccm2
gene id: 8090:ccm2
uniprot id: H2MPA3
uniprot id: H2MPA5
names: Similarity
messages: Belongs to the CCM2 family.

8090:LOC101157220
gene id: 8090:LOC101157220
uniprot id: A0A3B3H7Y3
names: Subcellular Location Annotation
messages: Nucleus

8090:rps8
gene id: 8090:rps8
uniprot id: A0A3P9LVR8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

8090:LOC101172961
gene id: 8090:LOC101172961
uniprot id: H2MX29
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:snrnp200
gene id: 8090:snrnp200
uniprot id: H2MA31
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

8090:LOC101161266
gene id: 8090:LOC101161266
uniprot id: A0A3B3I4F6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8090:fnip1
gene id: 8090:fnip1
uniprot id: A0A3B3HV86
uniprot id: A0A3B3IM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

8090:LOC101160832
gene id: 8090:LOC101160832
uniprot id: A0A3B3IL92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8090:ddrgk1
gene id: 8090:ddrgk1
uniprot id: H2L8H1
names: Similarity
messages: Belongs to the DDRGK1 family.

8090:dusp5
gene id: 8090:dusp5
uniprot id: A0A3P9JL20
uniprot id: H2MK20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

8090:nrp2
gene id: 8090:nrp2
uniprot id: H2LL92
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101157893
gene id: 8090:LOC101157893
uniprot id: H2MAW5
names: Similarity
messages: Belongs to the syntaxin family.

8090:hhatl
gene id: 8090:hhatl
uniprot id: H2M8U7
names: Subcellular Location Annotation
messages: Membrane

8090:nagk
gene id: 8090:nagk
uniprot id: H2LMY5
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

8090:lias
gene id: 8090:lias
uniprot id: A0A3B3IH16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

8090:LOC101155025
gene id: 8090:LOC101155025
uniprot id: H2LAS9
uniprot id: H2M643
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8090:LOC101155257
gene id: 8090:LOC101155257
uniprot id: A0A3P9K6F7
uniprot id: H2M989
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8090:acadvl
gene id: 8090:acadvl
uniprot id: H2LR71
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8090:bcar1
gene id: 8090:bcar1
uniprot id: A0A3B3HDJ7
uniprot id: A0A3B3IMP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

8090:LOC101162622
gene id: 8090:LOC101162622
uniprot id: A0A3P9LX46
names: Subcellular Location Annotation
messages: Membrane

8090:ak1
gene id: 8090:ak1
uniprot id: A0A3B3HBM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

8090:LOC101171770
gene id: 8090:LOC101171770
uniprot id: A0A3B3HL67
uniprot id: A0A3P9H3T5
names: Subcellular Location Annotation
messages: Nucleus

8090:sf3b6
gene id: 8090:sf3b6
uniprot id: A0A3P9LUT8
uniprot id: H2MMM4
names: Subcellular Location Annotation
messages: Nucleus

8090:insl5
gene id: 8090:insl5
uniprot id: A0A3P9KPI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8090:mrps36
gene id: 8090:mrps36
uniprot id: A0A3B3IEQ4
uniprot id: A0A3P9K3S8
names: Subcellular Location Annotation
messages: Mitochondrion

8090:LOC101170270
gene id: 8090:LOC101170270
uniprot id: H3K3Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:LOC101160435
gene id: 8090:LOC101160435
uniprot id: H2LHS3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101156783
gene id: 8090:LOC101156783
uniprot id: H2ME50
names: Similarity
messages: Belongs to the MARCKS family.

8090:LOC101171584
gene id: 8090:LOC101171584
uniprot id: A0A3B3HEX0
names: Similarity
messages: Belongs to the DEAD box helicase family.

8090:LOC101155934
gene id: 8090:LOC101155934
uniprot id: A0A3P9H3W0
uniprot id: H2M798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

8090:egr1
gene id: 8090:egr1
uniprot id: B9ZYZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

8090:shmt2
gene id: 8090:shmt2
uniprot id: H2LLQ5
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

8090:LOC101166940
gene id: 8090:LOC101166940
uniprot id: A0A3B3H4F7
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

8090:engase
gene id: 8090:engase
uniprot id: H2MS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

8090:epha4
gene id: 8090:epha4
uniprot id: H2LYR1
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

8090:msx1
gene id: 8090:msx1
uniprot id: A0A3P9KSB5
uniprot id: H2MQB9
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC100049282
gene id: 8090:LOC100049282
uniprot id: A0A3B3ILA3
uniprot id: A0A3B3IMI7
uniprot id: A0A3P9JM48
uniprot id: A0A3P9LGN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8090:LOC101167049
gene id: 8090:LOC101167049
uniprot id: H2L8J8
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8090:vamp2
gene id: 8090:vamp2
uniprot id: A0A3P9H3X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

8090:LOC101166911
gene id: 8090:LOC101166911
uniprot id: A0A3B3I6M4
uniprot id: A0A3P9LT74
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:aup1
gene id: 8090:aup1
uniprot id: H2M0Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AUP1 family.
messages: Membrane

8090:LOC101155137
gene id: 8090:LOC101155137
uniprot id: H2LEN8
names: Similarity
messages: Belongs to the COX20 family.

8090:vps36
gene id: 8090:vps36
uniprot id: A0A3B3HGP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

8090:mmd2
gene id: 8090:mmd2
uniprot id: A0A3B3HFK1
uniprot id: A0A3P9IFP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8090:pfdn6
gene id: 8090:pfdn6
uniprot id: H2M2B2
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

8090:cnp
gene id: 8090:cnp
uniprot id: A0A3B3HRB5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2H phosphoesterase superfamily. CNPase family.
messages: Exists as monomers and homodimers.
messages: Melanosome
messages: Membrane

8090:stam
gene id: 8090:stam
uniprot id: H2MUD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

8090:atp13a1
gene id: 8090:atp13a1
uniprot id: A0A3B3HYE3
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

8090:trip13
gene id: 8090:trip13
uniprot id: A0A3P9IGV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

8090:LOC101165144
gene id: 8090:LOC101165144
uniprot id: A0A3P9HH05
uniprot id: H2MFN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

8090:shmt1
gene id: 8090:shmt1
uniprot id: A0A3P9KGU6
uniprot id: H2MFA3
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

8090:dnajb12
gene id: 8090:dnajb12
uniprot id: H2LZG5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:mmab
gene id: 8090:mmab
uniprot id: H2LT81
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

8090:LOC101168858
gene id: 8090:LOC101168858
uniprot id: A0A3B3H725
names: Similarity
messages: Belongs to the DIPK family.

8090:LOC101155046
gene id: 8090:LOC101155046
uniprot id: A0A3P9LE04
uniprot id: H2LXP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8090:ppp2ca
gene id: 8090:ppp2ca
uniprot id: A0A3P9LJM6
uniprot id: H2L5S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8090:kpnb1
gene id: 8090:kpnb1
uniprot id: A0A3P9MP49
uniprot id: H2N069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

8090:g6pc
gene id: 8090:g6pc
uniprot id: A0A3B3H714
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8090:rad17
gene id: 8090:rad17
uniprot id: H2MSE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

8090:slc39a6
gene id: 8090:slc39a6
uniprot id: A0A3B3H6E6
names: Subcellular Location Annotation
messages: Membrane

8090:slc27a4
gene id: 8090:slc27a4
uniprot id: A0A3B3IDV8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8090:jun
gene id: 8090:jun
uniprot id: H2M2L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8090:mrps21
gene id: 8090:mrps21
uniprot id: A0A3B3IIY0
uniprot id: A0A3P9KFA3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

8090:LOC101162224
gene id: 8090:LOC101162224
uniprot id: A0A3B3HEK8
uniprot id: A0A3P9H6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

8090:slc20a2
gene id: 8090:slc20a2
uniprot id: H2L8U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

8090:oxsm
gene id: 8090:oxsm
uniprot id: H2LXJ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

8090:mks1
gene id: 8090:mks1
uniprot id: H2MHH5
names: Subcellular Location Annotation
messages: cilium basal body

8090:LOC101157337
gene id: 8090:LOC101157337
uniprot id: H2MSD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:ppil3
gene id: 8090:ppil3
uniprot id: H2L5B2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8090:LOC101159887
gene id: 8090:LOC101159887
uniprot id: A0A3P9L485
uniprot id: Q76N20
names: Similarity
messages: Belongs to the actin family.

8090:mrpl58
gene id: 8090:mrpl58
uniprot id: H2N2L5
names: Subcellular Location Annotation
messages: Mitochondrion

8090:psme4
gene id: 8090:psme4
uniprot id: A0A3B3HPT4
names: Similarity
messages: Belongs to the BLM10 family.

8090:LOC101160076
gene id: 8090:LOC101160076
uniprot id: H2LFC7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

8090:LOC101171103
gene id: 8090:LOC101171103
uniprot id: H2LP07
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

8090:LOC101167073
gene id: 8090:LOC101167073
uniprot id: A0A3P9LXQ9
names: Similarity
messages: Belongs to the ubiquitin family.

8090:slc35f2
gene id: 8090:slc35f2
uniprot id: H2MJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

8090:LOC101162549
gene id: 8090:LOC101162549
uniprot id: H2LWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

8090:LOC101170651
gene id: 8090:LOC101170651
uniprot id: H2M3H2
names: Similarity
messages: Belongs to the AKAP95 family.

8090:nanog
gene id: 8090:nanog
uniprot id: B7U5S3
names: Subcellular Location Annotation
messages: Nucleus

8090:map2k2
gene id: 8090:map2k2
uniprot id: H2LJN3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:ccne1
gene id: 8090:ccne1
uniprot id: H2ML55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8090:LOC101162866
gene id: 8090:LOC101162866
uniprot id: H2LBI4
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101161757
gene id: 8090:LOC101161757
uniprot id: A0A3B3IBS5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8090:fbxo46
gene id: 8090:fbxo46
uniprot id: A0A3B3HE54
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

8090:kcnmb4
gene id: 8090:kcnmb4
uniprot id: A0A3P9LTK6
uniprot id: H2MSI0
names: Subcellular Location Annotation
messages: Membrane

8090:ube2n
gene id: 8090:ube2n
uniprot id: A0A3P9J9D9
uniprot id: H2M6P5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:LOC101164253
gene id: 8090:LOC101164253
uniprot id: H2LY28
names: Similarity
messages: Belongs to the CCDC39 family.

8090:LOC101155573
gene id: 8090:LOC101155573
uniprot id: A0A3B3IF01
names: Subcellular Location Annotation
messages: Cytoplasm

8090:ap3b1
gene id: 8090:ap3b1
uniprot id: A0A3B3IGN3
uniprot id: A0A3B3IKH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

8090:camk2a
gene id: 8090:camk2a
uniprot id: A0A3P9KVR8
uniprot id: H2MC31
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8090:LOC101164611
gene id: 8090:LOC101164611
uniprot id: A0A3P9IL54
uniprot id: H2M871
names: Similarity
messages: Belongs to the UPF0046 family.

8090:LOC101159261
gene id: 8090:LOC101159261
uniprot id: H2LYH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8090:sod1
gene id: 8090:sod1
uniprot id: A0A3B3HWP6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

8090:rhot2
gene id: 8090:rhot2
uniprot id: A0A3B3I0G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

8090:tcf7l1
gene id: 8090:tcf7l1
uniprot id: F8T0U5
uniprot id: H2M8J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8090:LOC101161019
gene id: 8090:LOC101161019
uniprot id: H2MC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

8090:LOC101171549
gene id: 8090:LOC101171549
uniprot id: H2L6V9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8090:LOC101167135
gene id: 8090:LOC101167135
uniprot id: A0A3P9L6M0
uniprot id: H2LWE0
names: Similarity
messages: Belongs to the NifU family.

8090:LOC101155223
gene id: 8090:LOC101155223
uniprot id: H2LQH1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:cd36
gene id: 8090:cd36
uniprot id: H2MN10
names: Similarity
messages: Belongs to the CD36 family.

8090:LOC101156518
gene id: 8090:LOC101156518
uniprot id: A0A3B3IIM6
names: Similarity
messages: Belongs to the dapper family.

8090:LOC101170775
gene id: 8090:LOC101170775
uniprot id: A0A3B3HAS1
uniprot id: A0A3B3HS22
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8090:tmed10
gene id: 8090:tmed10
uniprot id: H2MSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101162945
gene id: 8090:LOC101162945
uniprot id: H2LJD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

8090:LOC101155847
gene id: 8090:LOC101155847
uniprot id: H2LHD3
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

8090:ruvbl2
gene id: 8090:ruvbl2
uniprot id: A0A3P9L218
uniprot id: H2M9D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

8090:LOC105355953
gene id: 8090:LOC105355953
uniprot id: A0A3B3HZC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:mfsd8
gene id: 8090:mfsd8
uniprot id: H2MYX1
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101159664
gene id: 8090:LOC101159664
uniprot id: H2M2J8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:gpr17
gene id: 8090:gpr17
uniprot id: H2MLB9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:stx5
gene id: 8090:stx5
uniprot id: A0A3P9I769
uniprot id: A0A3P9I784
uniprot id: H2LA94
uniprot id: H2LA97
names: Similarity
messages: Belongs to the syntaxin family.

8090:LOC101155769
gene id: 8090:LOC101155769
uniprot id: H2LBB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

8090:LOC101170114
gene id: 8090:LOC101170114
uniprot id: A0A3B3H5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8090:LOC101167873
gene id: 8090:LOC101167873
uniprot id: H2L9C5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8090:LOC101162708
gene id: 8090:LOC101162708
uniprot id: H2MQL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8090:maats1
gene id: 8090:maats1
uniprot id: H2MUK8
names: Similarity
messages: Belongs to the CFAP91 family.

8090:pts
gene id: 8090:pts
uniprot id: H2MD33
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

8090:atpaf1
gene id: 8090:atpaf1
uniprot id: A0A3B3HGQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

8090:LOC105356225
gene id: 8090:LOC105356225
uniprot id: A0A3B3I0A3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:LOC101156095
gene id: 8090:LOC101156095
uniprot id: H2L5J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8090:LOC101175317
gene id: 8090:LOC101175317
uniprot id: A0A3P9H3A6
uniprot id: H2LN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC101165159
gene id: 8090:LOC101165159
uniprot id: H2LGT3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101159427
gene id: 8090:LOC101159427
uniprot id: A0A3B3H9H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8090:LOC101160784
gene id: 8090:LOC101160784
uniprot id: A0A3P9MNP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101165231
gene id: 8090:LOC101165231
uniprot id: H2LGR2
names: Similarity
messages: Belongs to the TEX28 family.

8090:nme6
gene id: 8090:nme6
uniprot id: A0A3B3HU76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8090:fli1
gene id: 8090:fli1
uniprot id: A0A3B3HC65
uniprot id: A0A3B3IDP0
uniprot id: A0A3P9ID84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:nfyb
gene id: 8090:nfyb
uniprot id: A0A3P9JRS4
uniprot id: H2M916
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

8090:LOC101174292
gene id: 8090:LOC101174292
uniprot id: A0A3B3IFP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

8090:suv39h1
gene id: 8090:suv39h1
uniprot id: H2MZT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

8090:mtg2
gene id: 8090:mtg2
uniprot id: H2M8F8
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

8090:ncbp3
gene id: 8090:ncbp3
uniprot id: H2MF22
names: Similarity
messages: Belongs to the NCBP3 family.

8090:c18h20orf27
gene id: 8090:c18h20orf27
uniprot id: H2LUH0
names: Similarity
messages: Belongs to the ADISSP family.

8090:LOC101160980
gene id: 8090:LOC101160980
uniprot id: A0A3B3HBX5
names: Subcellular Location Annotation
messages: extracellular space

8090:sema4d
gene id: 8090:sema4d
uniprot id: H2LME8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:gpi
gene id: 8090:gpi
uniprot id: A0A3B3H9P7
names: Similarity
messages: Belongs to the GPI family.

8090:c6h11orf58
gene id: 8090:c6h11orf58
uniprot id: H2L6U8
names: Similarity
messages: Belongs to the SMAP family.

8090:foxb1
gene id: 8090:foxb1
uniprot id: C1K2Y2
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101167548
gene id: 8090:LOC101167548
uniprot id: H2L8M2
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155158
gene id: 8090:LOC101155158
uniprot id: A0A3B3IDW6
uniprot id: A0A3B3IL60
uniprot id: A0A3P9KD84
uniprot id: A0A3P9KDD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8090:chpf
gene id: 8090:chpf
uniprot id: A0A3B3HV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8090:rbks
gene id: 8090:rbks
uniprot id: A0A3B3HTS5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

8090:LOC101158846
gene id: 8090:LOC101158846
uniprot id: H2LGF9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

8090:trmt6
gene id: 8090:trmt6
uniprot id: H2M1T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

8090:LOC101167965
gene id: 8090:LOC101167965
uniprot id: A0A3B3IEZ6
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

8090:homer3
gene id: 8090:homer3
uniprot id: A0A3B3IEX1
uniprot id: A0A3B3IG28
uniprot id: H2LX61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8090:LOC101168044
gene id: 8090:LOC101168044
uniprot id: H2M3U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

8090:galnt2
gene id: 8090:galnt2
uniprot id: H2M5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8090:mmp14
gene id: 8090:mmp14
uniprot id: A0A3P9KF08
uniprot id: Q4W889
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:ngb
gene id: 8090:ngb
uniprot id: A0A3P9HDK5
names: Similarity
messages: Belongs to the globin family.

8090:wdfy1
gene id: 8090:wdfy1
uniprot id: H2LZR6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8090:ufd1
gene id: 8090:ufd1
uniprot id: H2LBH9
names: Similarity
messages: Belongs to the UFD1 family.

8090:tmem33
gene id: 8090:tmem33
uniprot id: A0A3P9KNM5
uniprot id: H2N0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

8090:agtpbp1
gene id: 8090:agtpbp1
uniprot id: H2LKZ4
uniprot id: H2LKZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

8090:abracl
gene id: 8090:abracl
uniprot id: H2MTV5
names: Similarity
messages: Belongs to the costars family.

8090:LOC101160184
gene id: 8090:LOC101160184
uniprot id: A0A3B3ICT4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

8090:LOC101171014
gene id: 8090:LOC101171014
uniprot id: A0A3P9ISG3
uniprot id: H2L8V3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:LOC101159115
gene id: 8090:LOC101159115
uniprot id: A0A3B3HAQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

8090:LOC101161173
gene id: 8090:LOC101161173
uniprot id: A0A3B3HNG0
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

8090:miox
gene id: 8090:miox
uniprot id: A0A3B3IG61
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

8090:dpt
gene id: 8090:dpt
uniprot id: A0A3B3I1M2
names: Similarity
messages: Belongs to the dermatopontin family.

8090:alpl
gene id: 8090:alpl
uniprot id: H2MRI0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

8090:LOC101158359
gene id: 8090:LOC101158359
uniprot id: H2MQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

8090:pole2
gene id: 8090:pole2
uniprot id: H2MC38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

8090:LOC101175316
gene id: 8090:LOC101175316
uniprot id: H2LAP2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8090:prmt5
gene id: 8090:prmt5
uniprot id: B1A4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

8090:mutyh
gene id: 8090:mutyh
uniprot id: H2LFS5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

8090:sec22a
gene id: 8090:sec22a
uniprot id: A0A3P9IFD9
uniprot id: H2M1M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

8090:LOC101172265
gene id: 8090:LOC101172265
uniprot id: A0A3B3I134
uniprot id: A0A3P9I8A6
uniprot id: H2LIN1
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

8090:gpr108
gene id: 8090:gpr108
uniprot id: H2M329
names: Subcellular Location Annotation
messages: Membrane

8090:neu3
gene id: 8090:neu3
uniprot id: A0A3B3IKD2
uniprot id: A0A3P9KA33
uniprot id: G3XKV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8090:tbx21
gene id: 8090:tbx21
uniprot id: A0A3B3HKU9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8090:med16
gene id: 8090:med16
uniprot id: A0A3P9M738
uniprot id: H2L329
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8090:vps18
gene id: 8090:vps18
uniprot id: H2MUW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

8090:adamts5
gene id: 8090:adamts5
uniprot id: A0A3B3HJD8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8090:pacsin1
gene id: 8090:pacsin1
uniprot id: A0A3B3IFS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell projection
messages: Cytoplasm
messages: Membrane

8090:c7h20orf24
gene id: 8090:c7h20orf24
uniprot id: A0A3B3HI34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:prr15l
gene id: 8090:prr15l
uniprot id: A0A3P9LJR8
names: Similarity
messages: Belongs to the PRR15 family.

8090:pde6c
gene id: 8090:pde6c
uniprot id: H2LKC9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8090:LOC101171760
gene id: 8090:LOC101171760
uniprot id: A0A3B3H8U8
names: Similarity
messages: Belongs to the nesprin family.

8090:LOC101175144
gene id: 8090:LOC101175144
uniprot id: H2LAL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC101172905
gene id: 8090:LOC101172905
uniprot id: A0A3P9MMB1
uniprot id: H2MZA4
names: Similarity
messages: Belongs to the peptidase C19 family.

8090:mfsd5
gene id: 8090:mfsd5
uniprot id: H2LUN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

8090:tmem97
gene id: 8090:tmem97
uniprot id: A0A3B3HAU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8090:LOC101157708
gene id: 8090:LOC101157708
uniprot id: A0A3B3HNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

8090:cpq
gene id: 8090:cpq
uniprot id: H2LIR5
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome

8090:ltv1
gene id: 8090:ltv1
uniprot id: H2L790
names: Similarity
messages: Belongs to the LTV1 family.

8090:LOC101174949
gene id: 8090:LOC101174949
uniprot id: A0A3P9JDZ8
uniprot id: H2MMZ1
names: Similarity
messages: Belongs to the PP2C family.

8090:LOC101162933
gene id: 8090:LOC101162933
uniprot id: A0A3P9MH01
uniprot id: H2LDM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC101161778
gene id: 8090:LOC101161778
uniprot id: A0A3P9I5H1
uniprot id: H2L385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101174511
gene id: 8090:LOC101174511
uniprot id: A0A3P9ILD7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:kmt2a
gene id: 8090:kmt2a
uniprot id: A0A3B3I6W2
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101163149
gene id: 8090:LOC101163149
uniprot id: H2MJQ1
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

8090:LOC101165762
gene id: 8090:LOC101165762
uniprot id: A0A3P9MF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:polr1a
gene id: 8090:polr1a
uniprot id: H2LXY4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

8090:med12
gene id: 8090:med12
uniprot id: A0A3B3H8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

8090:camlg
gene id: 8090:camlg
uniprot id: H2L5N0
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

8090:phykpl
gene id: 8090:phykpl
uniprot id: A0A3B3ICL4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

8090:LOC101169907
gene id: 8090:LOC101169907
uniprot id: H2L698
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC105356224
gene id: 8090:LOC105356224
uniprot id: H2MG51
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:tctn3
gene id: 8090:tctn3
uniprot id: H2LND5
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

8090:LOC101171614
gene id: 8090:LOC101171614
uniprot id: A0A3B3HFL1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:LOC101172311
gene id: 8090:LOC101172311
uniprot id: H2L308
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

8090:gata-1
gene id: 8090:gata-1
uniprot id: Q76B16
names: Subcellular Location Annotation
messages: Nucleus

8090:tp53i11
gene id: 8090:tp53i11
uniprot id: H2LIP1
names: Subcellular Location Annotation
messages: Membrane

8090:ssbp1
gene id: 8090:ssbp1
uniprot id: A0A3P9LZ30
uniprot id: H2MQE2
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

8090:LOC100049273
gene id: 8090:LOC100049273
uniprot id: A0A3P9M9E4
uniprot id: H2LIY2
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

8090:inpp4a
gene id: 8090:inpp4a
uniprot id: A0A3B3IG12
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

8090:vps37a
gene id: 8090:vps37a
uniprot id: A0A3P9L4W5
uniprot id: H2MZM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8090:LOC101166976
gene id: 8090:LOC101166976
uniprot id: A0A3P9MF16
uniprot id: H2L744
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:mfsd3
gene id: 8090:mfsd3
uniprot id: A0A3P9K4G2
uniprot id: H2MAF8
names: Subcellular Location Annotation
messages: Membrane

8090:rps3a
gene id: 8090:rps3a
uniprot id: O73813
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: Cytoplasm

8090:casp9
gene id: 8090:casp9
uniprot id: A0A3B3I922
uniprot id: A0A3B3I9X6
names: Similarity
messages: Belongs to the peptidase C14A family.

8090:LOC101160101
gene id: 8090:LOC101160101
uniprot id: A0A3B3HJ60
uniprot id: A0A3P9KYN3
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

8090:cnot11
gene id: 8090:cnot11
uniprot id: H2MGZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

8090:LOC101175425
gene id: 8090:LOC101175425
uniprot id: H2LA74
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

8090:LOC101167011
gene id: 8090:LOC101167011
uniprot id: A0A3B3H5S8
uniprot id: A0A3P9KZI7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8090:psmb7
gene id: 8090:psmb7
uniprot id: A0A3P9LVV8
uniprot id: H2MD69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8090:LOC101166548
gene id: 8090:LOC101166548
uniprot id: H2MLN9
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101175559
gene id: 8090:LOC101175559
uniprot id: H2M108
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

8090:pde7a
gene id: 8090:pde7a
uniprot id: H2LXA7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8090:nhp2
gene id: 8090:nhp2
uniprot id: A0A3B3HCY7
uniprot id: A0A3P9LQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

8090:LOC105354097
gene id: 8090:LOC105354097
uniprot id: A0A3B3HIT6
uniprot id: A0A3B3HUS1
uniprot id: A0A3B3IPF6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:cxadr
gene id: 8090:cxadr
uniprot id: H2MAN9
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101175418
gene id: 8090:LOC101175418
uniprot id: H2M587
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8090:eif2b4
gene id: 8090:eif2b4
uniprot id: H2MNS3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

8090:rbm42
gene id: 8090:rbm42
uniprot id: H2LE43
names: Similarity
messages: Belongs to the RRM RBM42 family.

8090:LOC101171182
gene id: 8090:LOC101171182
uniprot id: H2LVS2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC100125511
gene id: 8090:LOC100125511
uniprot id: H2M6A6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101164509
gene id: 8090:LOC101164509
uniprot id: H2LRD2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101168626
gene id: 8090:LOC101168626
uniprot id: A0A3P9LES9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8090:LOC101154795
gene id: 8090:LOC101154795
uniprot id: A0A3P9LDX1
uniprot id: H2LXM9
names: Subcellular Location Annotation
messages: Nucleus

8090:pard3
gene id: 8090:pard3
uniprot id: H2L9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

8090:arcn1
gene id: 8090:arcn1
uniprot id: A0A3B3I7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

8090:rad51d
gene id: 8090:rad51d
uniprot id: H2MK81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus

8090:LOC101170759
gene id: 8090:LOC101170759
uniprot id: H2LTI0
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101162768
gene id: 8090:LOC101162768
uniprot id: A0A3P9L7T4
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

8090:LOC101170049
gene id: 8090:LOC101170049
uniprot id: A0A3P9JA15
uniprot id: H2M8Z5
names: Similarity
messages: Belongs to the ATG8 family.

8090:tbce
gene id: 8090:tbce
uniprot id: H2L6T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

8090:LOC101161889
gene id: 8090:LOC101161889
uniprot id: A0A3B3HG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

8090:LOC101171135
gene id: 8090:LOC101171135
uniprot id: A0A3B3IBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

8090:ndufaf2
gene id: 8090:ndufaf2
uniprot id: A0A3P9LHH9
uniprot id: H2LI90
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

8090:kcnc1
gene id: 8090:kcnc1
uniprot id: A0A3P9M356
uniprot id: H2LN21
uniprot id: H2LN22
names: Subcellular Location Annotation
messages: Membrane

8090:dhrs11
gene id: 8090:dhrs11
uniprot id: H2M6Z5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:LOC101168685
gene id: 8090:LOC101168685
uniprot id: A0A3B3HWX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

8090:LOC101170433
gene id: 8090:LOC101170433
uniprot id: A0A3P9H9N3
uniprot id: H2L9K8
names: Similarity
messages: Belongs to the WD repeat coronin family.

8090:fam49a
gene id: 8090:fam49a
uniprot id: A0A3P9GYX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

8090:col4a1
gene id: 8090:col4a1
uniprot id: D2KY92
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

8090:KEF90 p10
gene id: 8090:KEF90_p10
uniprot id: Q8HLX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8090:LOC101170669
gene id: 8090:LOC101170669
uniprot id: A0A3P9KZZ3
uniprot id: H2LPR5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

8090:pld1
gene id: 8090:pld1
uniprot id: A0A3B3IDY9
names: Similarity
messages: Belongs to the phospholipase D family.

8090:LOC101162292
gene id: 8090:LOC101162292
uniprot id: A0A3B3H634
names: Similarity
messages: Belongs to the glutaminase family.

8090:LOC101164888
gene id: 8090:LOC101164888
uniprot id: H2LFQ0
names: Similarity
messages: Belongs to the SHMT family.

8090:hoxc9
gene id: 8090:hoxc9
uniprot id: Q9PVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8090:LOC101155285
gene id: 8090:LOC101155285
uniprot id: H2M654
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

8090:actr8
gene id: 8090:actr8
uniprot id: A0A3B3HQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

8090:olgc7
gene id: 8090:olgc7
uniprot id: Q98UI1
uniprot id: Q9YGW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

8090:taf5
gene id: 8090:taf5
uniprot id: H2MCI9
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

8090:ydjc
gene id: 8090:ydjc
uniprot id: H2MSF5
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

8090:desi1
gene id: 8090:desi1
uniprot id: A0A3P9JRI3
uniprot id: H2MDF1
names: Similarity
messages: Belongs to the DeSI family.

8090:lce
gene id: 8090:lce
uniprot id: P31579
names: Cofactor
names: Developmental Stage
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In medaka the hatching enzyme system is composed of two distinct proteases, the high choriolytic enzyme (HCE), of which there are two isoforms, and the low choriolytic enzyme (LCE).
messages: Participates in the breakdown of the egg envelope, which is derived from the egg extracellular matrix, at the time of hatching. Thus allowing the newly hatched fish to swim free. LCE solubilizes the egg envelope only after it has been swollen by the action of HCE.
messages: Production of the protein starts in day 2 to day 3 embryos and increases thereafter until hatching.
messages: Zymogen granule

8090:ercc4
gene id: 8090:ercc4
uniprot id: H2LCP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

8090:LOC101173704
gene id: 8090:LOC101173704
uniprot id: A0A3P9H922
uniprot id: H2MK47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

8090:LOC101155548
gene id: 8090:LOC101155548
uniprot id: A0A3P9JGR4
uniprot id: H2M4J3
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8090:naxe
gene id: 8090:naxe
uniprot id: H2LYI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted

8090:slbp
gene id: 8090:slbp
uniprot id: A0A3B3I9P9
names: Similarity
messages: Belongs to the SLBP family.

8090:pcyt1a
gene id: 8090:pcyt1a
uniprot id: A0A3B3HBH1
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

8090:epn2
gene id: 8090:epn2
uniprot id: H2MB49
names: Similarity
messages: Belongs to the epsin family.

8090:med31
gene id: 8090:med31
uniprot id: A0A3P9IEW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8090:LOC101163589
gene id: 8090:LOC101163589
uniprot id: A0A3B3HAA9
uniprot id: A0A3P9LZ13
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:LOC101158122
gene id: 8090:LOC101158122
uniprot id: A0A3B3HK82
names: Similarity
messages: Belongs to the ARTD/PARP family.

8090:LOC101175509
gene id: 8090:LOC101175509
uniprot id: A0A3P9LYJ3
uniprot id: A0A3P9LZ83
uniprot id: H2MT98
uniprot id: H2MTA0
names: Similarity
messages: Belongs to the guanylate kinase family.

8090:opa3
gene id: 8090:opa3
uniprot id: A0A3P9LEZ3
uniprot id: H2L5Y0
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

8090:LOC101162532
gene id: 8090:LOC101162532
uniprot id: H2LQ88
names: Similarity
messages: Belongs to the TGF-beta family.

8090:enoph1
gene id: 8090:enoph1
uniprot id: A0A3P9H1L4
uniprot id: H2L8W7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

8090:cmtm4
gene id: 8090:cmtm4
uniprot id: H2LLH0
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101165996
gene id: 8090:LOC101165996
uniprot id: H2L657
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

8090:LOC101155799
gene id: 8090:LOC101155799
uniprot id: H2M464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

8090:LOC101156820
gene id: 8090:LOC101156820
uniprot id: A0A3P9K3F8
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8090:LOC101155348
gene id: 8090:LOC101155348
uniprot id: A0A3B3IC11
names: Subcellular Location Annotation
messages: cytoskeleton

8090:LOC101156818
gene id: 8090:LOC101156818
uniprot id: H2MJX5
names: Similarity
messages: Belongs to the SPATS2 family.

8090:LOC100301585
gene id: 8090:LOC100301585
uniprot id: H2LVZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

8090:LOC101173720
gene id: 8090:LOC101173720
uniprot id: A0A3B3IL07
uniprot id: A0A3P9KUR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

8090:mcm6
gene id: 8090:mcm6
uniprot id: H2M6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

8090:yif1a
gene id: 8090:yif1a
uniprot id: A0A3B3IAM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

8090:mars2
gene id: 8090:mars2
uniprot id: H2L5B3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8090:LOC100302444
gene id: 8090:LOC100302444
uniprot id: C4B4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

8090:dtymk
gene id: 8090:dtymk
uniprot id: H2L9K3
names: Similarity
messages: Belongs to the thymidylate kinase family.

8090:LOC101155876
gene id: 8090:LOC101155876
uniprot id: A0A3B3I0V4
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101157313
gene id: 8090:LOC101157313
uniprot id: A0A3P9L604
uniprot id: H2LBD8
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

8090:ints3
gene id: 8090:ints3
uniprot id: H2L7P6
names: Similarity
messages: Belongs to the Integrator subunit 3 family.

8090:rpe
gene id: 8090:rpe
uniprot id: A0A3B3IAA6
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

8090:LOC101155447
gene id: 8090:LOC101155447
uniprot id: A0A3B3I0E3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:LOC101167353
gene id: 8090:LOC101167353
uniprot id: A0A3B3IHD1
uniprot id: H2LP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

8090:LOC101167870
gene id: 8090:LOC101167870
uniprot id: H2LT24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8090:slco5a1
gene id: 8090:slco5a1
uniprot id: H2LVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8090:fggy
gene id: 8090:fggy
uniprot id: H2M2K7
names: Similarity
messages: Belongs to the FGGY kinase family.

8090:LOC101164801
gene id: 8090:LOC101164801
uniprot id: H2M5U1
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8090:ggtl1b
gene id: 8090:ggtl1b
uniprot id: A0A3B3I4E0
uniprot id: F1C7I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8090:LOC101170644
gene id: 8090:LOC101170644
uniprot id: A0A3B3HQP8
uniprot id: A0A3P9H9T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:dtx1
gene id: 8090:dtx1
uniprot id: A0A3B3IBN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8090:LOC101169374
gene id: 8090:LOC101169374
uniprot id: H2M2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8090:LOC101156310
gene id: 8090:LOC101156310
uniprot id: H2LM40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8090:hacl1
gene id: 8090:hacl1
uniprot id: H2LSZ0
names: Similarity
messages: Belongs to the TPP enzyme family.

8090:mrpl12
gene id: 8090:mrpl12
uniprot id: A0A3P9LLN8
uniprot id: H2LS42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

8090:LOC101162431
gene id: 8090:LOC101162431
uniprot id: A0A3B3IFD1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8090:myt1
gene id: 8090:myt1
uniprot id: A0A3B3HMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

8090:LOC101166445
gene id: 8090:LOC101166445
uniprot id: A0A3B3HBB9
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

8090:pus1
gene id: 8090:pus1
uniprot id: H2M509
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

8090:tns4
gene id: 8090:tns4
uniprot id: A0A3B3I685
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

8090:kcnj8
gene id: 8090:kcnj8
uniprot id: A0A3P9HCR5
uniprot id: H2MRK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:LOC101173302
gene id: 8090:LOC101173302
uniprot id: A0A3B3I5Y9
uniprot id: A0A3P9HAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

8090:tctex1d2
gene id: 8090:tctex1d2
uniprot id: A0A3P9L715
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

8090:LOC101157032
gene id: 8090:LOC101157032
uniprot id: H2L2Y2
names: Similarity
messages: Belongs to the hexokinase family.

8090:LOC101159736
gene id: 8090:LOC101159736
uniprot id: A0A3B3HCB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8090:LOC101169648
gene id: 8090:LOC101169648
uniprot id: A0A3B3H9J3
uniprot id: A0A3P9JBA5
uniprot id: A0A3P9M9J2
uniprot id: H2MHE9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

8090:tspan11
gene id: 8090:tspan11
uniprot id: H2MJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC101165726
gene id: 8090:LOC101165726
uniprot id: H2L7S5
uniprot id: H2L7S8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101156995
gene id: 8090:LOC101156995
uniprot id: H2LQV4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

8090:LOC101166845
gene id: 8090:LOC101166845
uniprot id: H2L9U4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC100301594
gene id: 8090:LOC100301594
uniprot id: Q3V635
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8090:opn3
gene id: 8090:opn3
uniprot id: R9R6D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8090:LOC101156643
gene id: 8090:LOC101156643
uniprot id: A0A3B3I0P2
uniprot id: A0A3P9K7Z3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8090:LOC101171042
gene id: 8090:LOC101171042
uniprot id: A0A3P9I6U6
uniprot id: H2MAU1
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8090:LOC101158069
gene id: 8090:LOC101158069
uniprot id: H2M066
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8090:gnrh2
gene id: 8090:gnrh2
uniprot id: Q9DGC9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the GnRH family.
messages: Expressed in the cell bodies of a cluster of neurons in the midbrain tegmentum.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.
messages: Teleost species possess three paralogous GnRHs: mdGnRH and cGnRH-II have been identified in tetrapods; sGnRH has no tetrapod ortholog and is thought to be a duplication of cGnRH-II.

8090:kmt5a
gene id: 8090:kmt5a
uniprot id: H2L7W0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8090:LOC101157649
gene id: 8090:LOC101157649
uniprot id: A0A3B3I5J4
names: Similarity
messages: Belongs to the HARBI1 family.

8090:taf12
gene id: 8090:taf12
uniprot id: A0A3B3H6B2
uniprot id: A0A3P9MMA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

8090:lrrn3
gene id: 8090:lrrn3
uniprot id: H2M4D7
names: Subcellular Location Annotation
messages: Membrane

8090:psmb9-like
gene id: 8090:psmb9-like
uniprot id: Q8UUL9
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8090:pus7
gene id: 8090:pus7
uniprot id: A0A3B3HHZ8
uniprot id: H2LBN5
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

8090:ppard
gene id: 8090:ppard
uniprot id: C4B6E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8090:LOC101174124
gene id: 8090:LOC101174124
uniprot id: H2MIK8
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

8090:efna3
gene id: 8090:efna3
uniprot id: A0A3B3IGE1
uniprot id: A0A3P9M304
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101169770
gene id: 8090:LOC101169770
uniprot id: H2MHU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8090:eif2b2
gene id: 8090:eif2b2
uniprot id: A0A3B3HME1
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

8090:acvr1
gene id: 8090:acvr1
uniprot id: H2MQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

8090:LOC101173734
gene id: 8090:LOC101173734
uniprot id: H2LHM7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:LOC101168329
gene id: 8090:LOC101168329
uniprot id: H2M1H2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

8090:lcn2
gene id: 8090:lcn2
uniprot id: A0A3B3I5X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8090:trove2
gene id: 8090:trove2
uniprot id: H2M5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

8090:LOC105356854
gene id: 8090:LOC105356854
uniprot id: A0A3B3I990
names: Similarity
messages: Belongs to the CD200R family.

8090:park7
gene id: 8090:park7
uniprot id: A0A3P9ML90
uniprot id: Q5W7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

8090:ppt1
gene id: 8090:ppt1
uniprot id: H2M157
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

8090:pgm2l1
gene id: 8090:pgm2l1
uniprot id: H2N2P0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8090:LOC101173649
gene id: 8090:LOC101173649
uniprot id: A0A3B3HCZ3
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8090:atp6v1d
gene id: 8090:atp6v1d
uniprot id: A0A3P9L444
uniprot id: H2M8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

8090:LOC101173066
gene id: 8090:LOC101173066
uniprot id: H2L8P8
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101154983
gene id: 8090:LOC101154983
uniprot id: H2M7P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule

8090:smc3
gene id: 8090:smc3
uniprot id: A0A3B3HL13
uniprot id: A0A3P9JLP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

8090:arl5b
gene id: 8090:arl5b
uniprot id: A0A3P9J666
uniprot id: H2M140
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8090:tbx4
gene id: 8090:tbx4
uniprot id: H2MIS9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8090:hoxc4
gene id: 8090:hoxc4
uniprot id: Q9PVS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Deformed subfamily.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8090:cdk10
gene id: 8090:cdk10
uniprot id: A0A3B3HNM1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:borcs5
gene id: 8090:borcs5
uniprot id: H2L611
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

8090:lpin1
gene id: 8090:lpin1
uniprot id: H2MQI8
names: Similarity
messages: Belongs to the lipin family.

8090:mrpl47
gene id: 8090:mrpl47
uniprot id: A0A3B3IH78
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

8090:pik3ip1
gene id: 8090:pik3ip1
uniprot id: H2LR32
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101162319
gene id: 8090:LOC101162319
uniprot id: A0A3B3IET1
names: Similarity
messages: Belongs to the DSD1 family.

8090:vps26a
gene id: 8090:vps26a
uniprot id: A0A3P9H1R5
uniprot id: H2M305
names: Similarity
messages: Belongs to the VPS26 family.

8090:araf
gene id: 8090:araf
uniprot id: A0A3P9HHE0
uniprot id: H2MQB2
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

8090:ar-alpha
gene id: 8090:ar-alpha
uniprot id: A0A3P9HIK8
uniprot id: A8CMD5
uniprot id: H2LW36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8090:c9h9orf3
gene id: 8090:c9h9orf3
uniprot id: A0A3B3IEU3
uniprot id: H2LHL9
names: Similarity
messages: Belongs to the peptidase M1 family.

8090:LOC101174174
gene id: 8090:LOC101174174
uniprot id: H2LAC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8090:LOC101155843
gene id: 8090:LOC101155843
uniprot id: A0A3P9M9C6
uniprot id: H2LRJ9
names: Subcellular Location Annotation
messages: extracellular space

8090:bysl
gene id: 8090:bysl
uniprot id: A0A3P9H898
uniprot id: H2L3I3
names: Similarity
messages: Belongs to the bystin family.

8090:LOC101165618
gene id: 8090:LOC101165618
uniprot id: A0A3P9MF16
uniprot id: H2L744
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101160650
gene id: 8090:LOC101160650
uniprot id: H2LEY8
uniprot id: H2LEZ2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8090:LOC101156114
gene id: 8090:LOC101156114
uniprot id: A0A3B3HUJ2
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

8090:LOC101174068
gene id: 8090:LOC101174068
uniprot id: A0A3B3I5U2
names: Similarity
messages: Belongs to the AHA1 family.

8090:eif3b
gene id: 8090:eif3b
uniprot id: A0A3P9KTR8
uniprot id: H2LYA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

8090:jph1
gene id: 8090:jph1
uniprot id: A0A3P9L4U4
uniprot id: H2LUW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

8090:LOC101156328
gene id: 8090:LOC101156328
uniprot id: A0A3B3HCF8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:tpd52
gene id: 8090:tpd52
uniprot id: A0A3B3H414
uniprot id: H2MCF3
uniprot id: H2MCF6
names: Similarity
messages: Belongs to the TPD52 family.

8090:pcmt1
gene id: 8090:pcmt1
uniprot id: H2MTF4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

8090:LOC101168052
gene id: 8090:LOC101168052
uniprot id: A0A3B3H7X5
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Membrane

8090:LOC101171299
gene id: 8090:LOC101171299
uniprot id: A0A3B3HFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8090:fgf3
gene id: 8090:fgf3
uniprot id: A0A3P9HA78
uniprot id: H2L3P4
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8090:cse1l
gene id: 8090:cse1l
uniprot id: A0A3B3IBJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

8090:LOC101158271
gene id: 8090:LOC101158271
uniprot id: A0A3P9M6P0
uniprot id: H2LJE2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8090:LOC101164606
gene id: 8090:LOC101164606
uniprot id: A0A3B3HT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:smarcad1
gene id: 8090:smarcad1
uniprot id: H2LJE4
names: Subcellular Location Annotation
messages: Chromosome

8090:LOC101157351
gene id: 8090:LOC101157351
uniprot id: H2MA35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8090:LOC101166592
gene id: 8090:LOC101166592
uniprot id: A0A3B3I2K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

8090:LOC101173003
gene id: 8090:LOC101173003
uniprot id: A0A3B3IF69
names: Subcellular Location Annotation
messages: Cell membrane

8090:LOC101170887
gene id: 8090:LOC101170887
uniprot id: A0A3B3IE33
uniprot id: A0A3P9H8L2
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

8090:LOC101157385
gene id: 8090:LOC101157385
uniprot id: H2M1A4
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101159746
gene id: 8090:LOC101159746
uniprot id: H2LY64
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane

8090:LOC101175444
gene id: 8090:LOC101175444
uniprot id: H2MBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8090:tbcd
gene id: 8090:tbcd
uniprot id: H2LSP3
names: Similarity
messages: Belongs to the TBCD family.

8090:LOC101174099
gene id: 8090:LOC101174099
uniprot id: H2LM68
names: Similarity
messages: Belongs to the TMEM178 family.

8090:hbp1
gene id: 8090:hbp1
uniprot id: H2LHP8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

8090:LOC101172023
gene id: 8090:LOC101172023
uniprot id: A0A3P9L6A6
uniprot id: H2MKD1
names: Subcellular Location Annotation
messages: Membrane

8090:mknk1
gene id: 8090:mknk1
uniprot id: H2MPT3
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:xkrx
gene id: 8090:xkrx
uniprot id: H2L7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8090:LOC101174205
gene id: 8090:LOC101174205
uniprot id: H2M4C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

8090:fermt1
gene id: 8090:fermt1
uniprot id: H2M1Q7
names: Similarity
messages: Belongs to the kindlin family.

8090:LOC101161174
gene id: 8090:LOC101161174
uniprot id: H2LK75
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:c24h6orf58
gene id: 8090:c24h6orf58
uniprot id: H2MUY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

8090:LOC101167888
gene id: 8090:LOC101167888
uniprot id: A0A3P9LFG3
uniprot id: H2L7K3
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

8090:rax
gene id: 8090:rax
uniprot id: Q90WR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

8090:LOC101166327
gene id: 8090:LOC101166327
uniprot id: H2M4H1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8090:LOC101156172
gene id: 8090:LOC101156172
uniprot id: H2LCE8
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

8090:st8sia5
gene id: 8090:st8sia5
uniprot id: A0A3B3HAL6
uniprot id: Q5K019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:xirp2
gene id: 8090:xirp2
uniprot id: A0A3B3HWC7
names: Domain
names: Similarity
messages: Belongs to the Xin family.
messages: Xin repeats bind F-actin.

8090:cops4
gene id: 8090:cops4
uniprot id: A0A3B3HTP3
uniprot id: A0A3P9IRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

8090:LOC101166401
gene id: 8090:LOC101166401
uniprot id: H2LVZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101164391
gene id: 8090:LOC101164391
uniprot id: H2MLT6
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

8090:LOC101165110
gene id: 8090:LOC101165110
uniprot id: A0A3B3IP96
uniprot id: A0A3P9I1L8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8090:LOC101160102
gene id: 8090:LOC101160102
uniprot id: A0A3B3I2N3
names: Similarity
messages: Belongs to the FAM110 family.

8090:LOC105354871
gene id: 8090:LOC105354871
uniprot id: H2LB01
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8090:s100z
gene id: 8090:s100z
uniprot id: A0A3B3HQ79
names: Similarity
messages: Belongs to the S-100 family.

8090:gtf2b
gene id: 8090:gtf2b
uniprot id: A0A3P9K2E5
names: Similarity
messages: Belongs to the TFIIB family.

8090:fgfr1op2
gene id: 8090:fgfr1op2
uniprot id: H2M0W0
names: Similarity
messages: Belongs to the SIKE family.

8090:LOC101158892
gene id: 8090:LOC101158892
uniprot id: A0A3B3HMY4
names: Subcellular Location Annotation
messages: Nucleus

8090:camsap2
gene id: 8090:camsap2
uniprot id: A0A3B3H898
uniprot id: H2LRE3
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8090:rpn2
gene id: 8090:rpn2
uniprot id: H2M7R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8090:LOC101169506
gene id: 8090:LOC101169506
uniprot id: H2M8S8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8090:sumo1
gene id: 8090:sumo1
uniprot id: A0A3P9LYE3
uniprot id: C9E6G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8090:rpl15
gene id: 8090:rpl15
uniprot id: A0A3P9KWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: Cytoplasm

8090:psme1
gene id: 8090:psme1
uniprot id: A0A3P9LS96
uniprot id: H2LP64
names: Similarity
messages: Belongs to the PA28 family.

8090:praf2
gene id: 8090:praf2
uniprot id: A0A3B3IJR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

8090:g6pc3
gene id: 8090:g6pc3
uniprot id: H2M6V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

8090:cnnm1
gene id: 8090:cnnm1
uniprot id: H2LUE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Metal transporter.

8090:eif4a3
gene id: 8090:eif4a3
uniprot id: H2MW23
names: Similarity
messages: Belongs to the DEAD box helicase family.

8090:spi1
gene id: 8090:spi1
uniprot id: A0A3B3I6D0
uniprot id: A0A3P9MA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:LOC101161323
gene id: 8090:LOC101161323
uniprot id: A0A3B3IIE6
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101169773
gene id: 8090:LOC101169773
uniprot id: A0A3B3I7P0
uniprot id: H2LZW8
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

8090:ddit4l
gene id: 8090:ddit4l
uniprot id: A0A3B3HHC9
names: Similarity
messages: Belongs to the DDIT4 family.

8090:id3
gene id: 8090:id3
uniprot id: A0A3B3H6I5
names: Subcellular Location Annotation
messages: Nucleus

8090:ska1
gene id: 8090:ska1
uniprot id: H2MWX1
names: Similarity
messages: Belongs to the SKA1 family.

8090:eif3f
gene id: 8090:eif3f
uniprot id: H2LB07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit F family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8090:LOC101156207
gene id: 8090:LOC101156207
uniprot id: H2M508
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8090:LOC101158803
gene id: 8090:LOC101158803
uniprot id: A0A3B3IG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8090:rad50
gene id: 8090:rad50
uniprot id: A0A3B3HZB0
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

8090:tas1r2b
gene id: 8090:tas1r2b
uniprot id: Q2MHK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:lpar3
gene id: 8090:lpar3
uniprot id: H2LNB7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:mettl1
gene id: 8090:mettl1
uniprot id: H2MK18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

8090:map2k4
gene id: 8090:map2k4
uniprot id: A0A3B3HCX2
uniprot id: A0A3B3I1T7
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:wnt1
gene id: 8090:wnt1
uniprot id: A0A3B3HWL2
uniprot id: A0A3P9JUM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8090:uba52
gene id: 8090:uba52
uniprot id: A0A3P9J6A3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

8090:pgm1
gene id: 8090:pgm1
uniprot id: H2M370
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8090:LOC101166066
gene id: 8090:LOC101166066
uniprot id: H2L636
names: Similarity
messages: Belongs to the arrestin family.

8090:ilf3
gene id: 8090:ilf3
uniprot id: A0A3B3I2N5
uniprot id: H2MP52
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:LOC101171200
gene id: 8090:LOC101171200
uniprot id: A0A3B3HV66
names: Similarity
messages: Belongs to the CAS family.

8090:LOC101159343
gene id: 8090:LOC101159343
uniprot id: H2LTF3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8090:tm4sf4
gene id: 8090:tm4sf4
uniprot id: A0A3B3I4C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8090:serf2
gene id: 8090:serf2
uniprot id: A0A3B3I2X9
uniprot id: A0A3P9IJV9
names: Similarity
messages: Belongs to the SERF family.

8090:dclre1b
gene id: 8090:dclre1b
uniprot id: H2LPK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

8090:LOC101167259
gene id: 8090:LOC101167259
uniprot id: A0A3B3IPY1
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8090:ska3
gene id: 8090:ska3
uniprot id: H2MDA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

8090:LOC101173236
gene id: 8090:LOC101173236
uniprot id: A0A3B3IC81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

8090:LOC101171309
gene id: 8090:LOC101171309
uniprot id: A0A3B3HA52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

8090:LOC101172281
gene id: 8090:LOC101172281
uniprot id: H2MS84
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8090:tmem47
gene id: 8090:tmem47
uniprot id: H2LLW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8090:LOC101162601
gene id: 8090:LOC101162601
uniprot id: A0A3B3I721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

8090:lin7a
gene id: 8090:lin7a
uniprot id: A0A3B3HQ30
uniprot id: A0A3P9J3N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8090:ano1
gene id: 8090:ano1
uniprot id: A0A3B3HBG0
uniprot id: A0A3B3HQ00
uniprot id: H2L3M2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101159772
gene id: 8090:LOC101159772
uniprot id: H2M4Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:tbxas1
gene id: 8090:tbxas1
uniprot id: H2MN99
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:rbm46
gene id: 8090:rbm46
uniprot id: A0A3B3I3C2
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101169678
gene id: 8090:LOC101169678
uniprot id: A0A3B3H8M2
names: Similarity
messages: Belongs to the TTC39 family.

8090:LOC101157056
gene id: 8090:LOC101157056
uniprot id: H2LMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

8090:dnmbp
gene id: 8090:dnmbp
uniprot id: A0A3B3HHA0
uniprot id: A0A3B3HKB2
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: Synapse
messages: cytoskeleton

8090:LOC101174660
gene id: 8090:LOC101174660
uniprot id: H2M0H9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

8090:rln3a
gene id: 8090:rln3a
uniprot id: Q0Q7C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8090:LOC101168926
gene id: 8090:LOC101168926
uniprot id: A0A3P9MJU6
uniprot id: H2LHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8090:higd2a
gene id: 8090:higd2a
uniprot id: A0A3B3H9L2
uniprot id: A0A3P9LYW5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

8090:cnksr1
gene id: 8090:cnksr1
uniprot id: H2MHH8
names: Similarity
messages: Belongs to the CNKSR family.

8090:st3gal5
gene id: 8090:st3gal5
uniprot id: H2LXL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:icmt
gene id: 8090:icmt
uniprot id: H2MYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101169963
gene id: 8090:LOC101169963
uniprot id: H2L5A0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:pomc
gene id: 8090:pomc
uniprot id: A0A3B3HM52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

8090:LOC101167482
gene id: 8090:LOC101167482
uniprot id: A0A3B3IME0
uniprot id: H2MHW8
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

8090:psmb8
gene id: 8090:psmb8
uniprot id: Q8UUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8090:adam23
gene id: 8090:adam23
uniprot id: A0A3B3HVT9
uniprot id: A0A3B3ICA6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101174399
gene id: 8090:LOC101174399
uniprot id: H2LCZ2
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

8090:LOC101157390
gene id: 8090:LOC101157390
uniprot id: H2LSY6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

8090:LOC101171416
gene id: 8090:LOC101171416
uniprot id: H2L3S8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

8090:kcnj15
gene id: 8090:kcnj15
uniprot id: H2MGU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:sdhaf4
gene id: 8090:sdhaf4
uniprot id: A0A3B3HH32
names: Similarity
messages: Belongs to the SDHAF4 family.

8090:LOC101169064
gene id: 8090:LOC101169064
uniprot id: A0A3B3HQ88
uniprot id: A0A3B3HZG0
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101174096
gene id: 8090:LOC101174096
uniprot id: H2LQX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:pitx1
gene id: 8090:pitx1
uniprot id: A0A3B3I6I8
uniprot id: A0A3B3IIZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

8090:tor4a
gene id: 8090:tor4a
uniprot id: H2L4F9
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

8090:pik3ca
gene id: 8090:pik3ca
uniprot id: H2LYJ3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8090:slc2a15b
gene id: 8090:slc2a15b
uniprot id: H2MC15
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8090:pkib
gene id: 8090:pkib
uniprot id: A0A3P9H8X4
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

8090:thumpd2
gene id: 8090:thumpd2
uniprot id: H2L9V7
names: Similarity
messages: Belongs to the methyltransferase superfamily.

8090:ptp4a1
gene id: 8090:ptp4a1
uniprot id: A0A3P9MMM3
uniprot id: H2L2Z1
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8090:sirt5
gene id: 8090:sirt5
uniprot id: H2MC35
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-98 and Arg-101) that bind to malonylated and succinylated substrates and define the specificity.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

8090:sparcl1
gene id: 8090:sparcl1
uniprot id: A4PE74
names: Similarity
messages: Belongs to the SPARC family.

8090:nup155
gene id: 8090:nup155
uniprot id: H2LTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

8090:LOC101155998
gene id: 8090:LOC101155998
uniprot id: A0A3P9HHE6
uniprot id: H2LUM5
names: Similarity
messages: Belongs to the cytochrome b5 family.

8090:gda
gene id: 8090:gda
uniprot id: H2M5A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

8090:ids
gene id: 8090:ids
uniprot id: H2LZB9
names: Similarity
messages: Belongs to the sulfatase family.

8090:ap4b1
gene id: 8090:ap4b1
uniprot id: H2L9Q9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

8090:LOC101171987
gene id: 8090:LOC101171987
uniprot id: A0A3B3IHS4
names: Similarity
messages: Belongs to the CAMK2N family.

8090:tom1l2
gene id: 8090:tom1l2
uniprot id: A0A3B3H946
uniprot id: A0A3B3I5R8
names: Similarity
messages: Belongs to the TOM1 family.

8090:utp15
gene id: 8090:utp15
uniprot id: H2L9R4
names: Subcellular Location Annotation
messages: nucleolus

8090:LOC101169682
gene id: 8090:LOC101169682
uniprot id: H2LYM2
names: Subcellular Location Annotation
messages: Nucleus

8090:hmgn3
gene id: 8090:hmgn3
uniprot id: A0A3B3HYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

8090:LOC101164675
gene id: 8090:LOC101164675
uniprot id: A0A3B3I2L3
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101164061
gene id: 8090:LOC101164061
uniprot id: H2M0Q4
names: Similarity
messages: Belongs to the TECPR1 family.

8090:pgd
gene id: 8090:pgd
uniprot id: H2LKL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

8090:snrnp27
gene id: 8090:snrnp27
uniprot id: H2MKY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

8090:LOC101168622
gene id: 8090:LOC101168622
uniprot id: A0A3P9J7N9
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8090:LOC101169003
gene id: 8090:LOC101169003
uniprot id: A0A3B3I436
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

8090:LOC101159542
gene id: 8090:LOC101159542
uniprot id: A0A3B3IHL0
names: Similarity
messages: Belongs to the SNF7 family.

8090:camk2n2
gene id: 8090:camk2n2
uniprot id: A0A3P9MD25
names: Similarity
messages: Belongs to the CAMK2N family.

8090:rflnb
gene id: 8090:rflnb
uniprot id: H2LWE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8090:LOC101155856
gene id: 8090:LOC101155856
uniprot id: H2L5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8090:fam199x
gene id: 8090:fam199x
uniprot id: A0A3P9JFE4
uniprot id: H2LZT3
names: Similarity
messages: Belongs to the FAM199 family.

8090:LOC101155833
gene id: 8090:LOC101155833
uniprot id: A0A3P9L2L6
uniprot id: H2LLC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8090:hsbp1
gene id: 8090:hsbp1
uniprot id: A0A3P9H122
uniprot id: H2MM35
names: Similarity
messages: Belongs to the HSBP1 family.

8090:LOC101162485
gene id: 8090:LOC101162485
uniprot id: H2LQJ8
names: Similarity
messages: Belongs to the TMEM14 family.

8090:LOC101163723
gene id: 8090:LOC101163723
uniprot id: A0A3B3I7C4
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101169981
gene id: 8090:LOC101169981
uniprot id: A0A3P9HHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

8090:sike1
gene id: 8090:sike1
uniprot id: H2L549
names: Similarity
messages: Belongs to the SIKE family.

8090:LOC101173373
gene id: 8090:LOC101173373
uniprot id: A0A3B3IPI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8090:LOC101173845
gene id: 8090:LOC101173845
uniprot id: H2LQM7
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8090:LOC101167886
gene id: 8090:LOC101167886
uniprot id: A0A3B3IJQ4
uniprot id: H2LKF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nectin family.
messages: Membrane

8090:trmt5
gene id: 8090:trmt5
uniprot id: H2MLW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

8090:LOC101169350
gene id: 8090:LOC101169350
uniprot id: H2M5G1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8090:p3h3
gene id: 8090:p3h3
uniprot id: H2MBJ1
names: Similarity
messages: Belongs to the leprecan family.

8090:me-t
gene id: 8090:me-t
uniprot id: O42100
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8090:cmtm6
gene id: 8090:cmtm6
uniprot id: H2MQZ9
names: Subcellular Location Annotation
messages: Membrane

8090:slc40a1
gene id: 8090:slc40a1
uniprot id: H2MKB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

8090:nlgn3
gene id: 8090:nlgn3
uniprot id: D2X2I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8090:LOC101165184
gene id: 8090:LOC101165184
uniprot id: A0A3B3I006
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101165821
gene id: 8090:LOC101165821
uniprot id: A0A3B3IK71
names: Similarity
messages: Belongs to the peptidase C1 family.

8090:LOC101162329
gene id: 8090:LOC101162329
uniprot id: A0A3B3HAH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: Mitochondrion inner membrane

8090:tmem177
gene id: 8090:tmem177
uniprot id: H2N2X3
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

8090:gsdf
gene id: 8090:gsdf
uniprot id: D4QE41
names: Similarity
messages: Belongs to the TGF-beta family.

8090:LOC101158902
gene id: 8090:LOC101158902
uniprot id: A0A3B3H574
uniprot id: A0A3B3HR37
uniprot id: A0A3P9HCV9
uniprot id: A0A3P9HDC9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:LOC101157221
gene id: 8090:LOC101157221
uniprot id: H2LCY7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:rx2
gene id: 8090:rx2
uniprot id: Q9I9A2
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Expressed in the retina from early somitogenesis (stage 19) onwards.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

8090:gnptab
gene id: 8090:gnptab
uniprot id: A0A3B3H9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

8090:LOC101173006
gene id: 8090:LOC101173006
uniprot id: A0A3P9MJY6
uniprot id: H2MHT3
names: Similarity
messages: Belongs to the EVA1 family.

8090:metap1
gene id: 8090:metap1
uniprot id: H2MTH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

8090:slc1a3
gene id: 8090:slc1a3
uniprot id: H2MGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8090:cdk5
gene id: 8090:cdk5
uniprot id: A0A3P9HIH1
uniprot id: H2MT54
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:pin4
gene id: 8090:pin4
uniprot id: H2LST9
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

8090:gpc5
gene id: 8090:gpc5
uniprot id: A0A3B3IJN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8090:orla-uba
gene id: 8090:orla-uba
uniprot id: H2LR16
names: Similarity
messages: Belongs to the MHC class I family.

8090:fdft1
gene id: 8090:fdft1
uniprot id: A0A3P9LLH7
uniprot id: H2MSH7
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

8090:LOC101174213
gene id: 8090:LOC101174213
uniprot id: H2LQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8090:LOC101166170
gene id: 8090:LOC101166170
uniprot id: A0A3B3IDM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

8090:ncoa3
gene id: 8090:ncoa3
uniprot id: H2M9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

8090:LOC101155626
gene id: 8090:LOC101155626
uniprot id: H2M1X1
names: Subcellular Location Annotation
messages: Nucleus

8090:cltrn
gene id: 8090:cltrn
uniprot id: H2MNZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:aste1
gene id: 8090:aste1
uniprot id: H2LFG5
names: Similarity
messages: Belongs to the asteroid family.

8090:LOC101163251
gene id: 8090:LOC101163251
uniprot id: H2MCH1
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8090:LOC101171800
gene id: 8090:LOC101171800
uniprot id: H2L6M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

8090:LOC101162853
gene id: 8090:LOC101162853
uniprot id: H2LBH1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8090:LOC101163410
gene id: 8090:LOC101163410
uniprot id: H2LEW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101168941
gene id: 8090:LOC101168941
uniprot id: A0A3P9H7B0
uniprot id: H2L3V5
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

8090:gclm
gene id: 8090:gclm
uniprot id: H2MRL9
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

8090:LOC101175017
gene id: 8090:LOC101175017
uniprot id: A0A3P9HJZ3
uniprot id: H2LUN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8090:pou6f1
gene id: 8090:pou6f1
uniprot id: A0A3B3HZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8090:hmgcs1
gene id: 8090:hmgcs1
uniprot id: A0A3B3HHR9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

8090:LOC101156570
gene id: 8090:LOC101156570
uniprot id: A0A3B3I5R6
uniprot id: A0A3P9JH93
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

8090:spc25
gene id: 8090:spc25
uniprot id: H2MRG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

8090:nono
gene id: 8090:nono
uniprot id: H2MBV1
names: Subcellular Location Annotation
messages: Nucleus speckle

8090:atp5mc3
gene id: 8090:atp5mc3
uniprot id: A0A3B3HXD1
uniprot id: A0A3P9I287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

8090:cdk6
gene id: 8090:cdk6
uniprot id: H2LGM4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:tvp23b
gene id: 8090:tvp23b
uniprot id: H2MFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

8090:kdm2a
gene id: 8090:kdm2a
uniprot id: H2LE59
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8090:otc
gene id: 8090:otc
uniprot id: H2LYY6
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

8090:LOC101158792
gene id: 8090:LOC101158792
uniprot id: H2LGL9
names: Similarity
messages: Belongs to the myozenin family.

8090:btk
gene id: 8090:btk
uniprot id: A0A3P9HY43
uniprot id: H2L5G0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8090:LOC101166100
gene id: 8090:LOC101166100
uniprot id: H2MH88
names: Similarity
messages: Belongs to the syntaxin family.

8090:hdac10
gene id: 8090:hdac10
uniprot id: A0A3B3HHN7
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.

8090:gal
gene id: 8090:gal
uniprot id: A0A3P9IKE7
uniprot id: H2MWP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

8090:cgas
gene id: 8090:cgas
uniprot id: A0A5S9HX20
names: Similarity
messages: Belongs to the mab-21 family.

8090:LOC101155381
gene id: 8090:LOC101155381
uniprot id: H2MLS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8090:trpt1
gene id: 8090:trpt1
uniprot id: A0A3B3IGN8
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

8090:LOC101171323
gene id: 8090:LOC101171323
uniprot id: H2LYT2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC101159702
gene id: 8090:LOC101159702
uniprot id: A0A3B3H6J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

8090:ccnb2
gene id: 8090:ccnb2
uniprot id: Q9IBG0
names: Developmental Stage
names: Function
names: Similarity
names: Subunit
messages: Accumulates steadily during G2 and is abruptly destroyed at mitosis.
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex (By similarity).

8090:arg2
gene id: 8090:arg2
uniprot id: H2M228
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

8090:LOC101155350
gene id: 8090:LOC101155350
uniprot id: A0A3B3IGI4
names: Similarity
messages: Belongs to the LSM14 family.

8090:LOC101166424
gene id: 8090:LOC101166424
uniprot id: H2LWU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101163303
gene id: 8090:LOC101163303
uniprot id: H2MY26
names: Subcellular Location Annotation
messages: Membrane

8090:slc6a11
gene id: 8090:slc6a11
uniprot id: A0A3P9MJI1
uniprot id: H2LIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:map2k5
gene id: 8090:map2k5
uniprot id: H2L9Y8
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:hdac9
gene id: 8090:hdac9
uniprot id: A0A3B3I6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus

8090:LOC101168421
gene id: 8090:LOC101168421
uniprot id: A0A3P9I5H1
uniprot id: H2L385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101157802
gene id: 8090:LOC101157802
uniprot id: H2LG88
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:kcnq4
gene id: 8090:kcnq4
uniprot id: H2M995
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101169105
gene id: 8090:LOC101169105
uniprot id: H2MQL2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8090:LOC101156601
gene id: 8090:LOC101156601
uniprot id: A0A3B3HZR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC101172927
gene id: 8090:LOC101172927
uniprot id: A0A3B3HBJ2
uniprot id: A0A3B3HTK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8090:LOC101173978
gene id: 8090:LOC101173978
uniprot id: A0A3B3H5X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101166285
gene id: 8090:LOC101166285
uniprot id: A0A3B3I3P8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:mrpl15
gene id: 8090:mrpl15
uniprot id: H2M7I0
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

8090:anapc2
gene id: 8090:anapc2
uniprot id: H2L6C9
names: Similarity
messages: Belongs to the cullin family.

8090:tmem173
gene id: 8090:tmem173
uniprot id: H2M1F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: autophagosome membrane
messages: perinuclear region

8090:ilkap
gene id: 8090:ilkap
uniprot id: H2MW32
names: Similarity
messages: Belongs to the PP2C family.

8090:LOC101168779
gene id: 8090:LOC101168779
uniprot id: A0A3B3HKT7
names: Similarity
messages: Belongs to the MDFI family.

8090:lsm1
gene id: 8090:lsm1
uniprot id: A0A3B3IPU5
uniprot id: A0A3P9K3J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

8090:pex1
gene id: 8090:pex1
uniprot id: A0A3B3I5J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: cytosol

8090:kansl2
gene id: 8090:kansl2
uniprot id: H2MPM7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

8090:mrpl34
gene id: 8090:mrpl34
uniprot id: H2LXR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

8090:bmp15
gene id: 8090:bmp15
uniprot id: H2LXF8
names: Similarity
messages: Belongs to the TGF-beta family.

8090:b4galt7
gene id: 8090:b4galt7
uniprot id: Q2HPN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8090:tmcc1
gene id: 8090:tmcc1
uniprot id: A0A3B3HSX5
uniprot id: A0A3B3I938
uniprot id: A0A3B3IL72
names: Similarity
messages: Belongs to the TEX28 family.

8090:LOC101171514
gene id: 8090:LOC101171514
uniprot id: H2LI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8090:LOC101164165
gene id: 8090:LOC101164165
uniprot id: A0A3B3HBW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

8090:LOC105356912
gene id: 8090:LOC105356912
uniprot id: H2LJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8090:hoxd12
gene id: 8090:hoxd12
uniprot id: H2MT45
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101168730
gene id: 8090:LOC101168730
uniprot id: H2L7F5
names: Subcellular Location Annotation
messages: Nucleus

8090:olah
gene id: 8090:olah
uniprot id: A0A3B3IFS4
uniprot id: A0A3P9L102
names: Similarity
messages: Belongs to the thioesterase family.

8090:LOC101171319
gene id: 8090:LOC101171319
uniprot id: A0A3P9HBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8090:LOC101172528
gene id: 8090:LOC101172528
uniprot id: A0A3B3I5E2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:mmp15
gene id: 8090:mmp15
uniprot id: Q76LU8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:snca
gene id: 8090:snca
uniprot id: A0A090D865
names: Similarity
messages: Belongs to the synuclein family.

8090:atp9a
gene id: 8090:atp9a
uniprot id: H2MNC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8090:LOC101170536
gene id: 8090:LOC101170536
uniprot id: A0A3B3H3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8090:LOC101156669
gene id: 8090:LOC101156669
uniprot id: H2MHK5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:LOC101156069
gene id: 8090:LOC101156069
uniprot id: H2LLJ0
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8090:map1lc3a
gene id: 8090:map1lc3a
uniprot id: A0A3B3H4S9
names: Similarity
messages: Belongs to the ATG8 family.

8090:eral1
gene id: 8090:eral1
uniprot id: H2M775
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.

8090:LOC101162673
gene id: 8090:LOC101162673
uniprot id: A0A3B3IJP4
uniprot id: A0A3P9LUV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

8090:kctd10
gene id: 8090:kctd10
uniprot id: A0A3B3H710
uniprot id: A0A3P9KXG9
names: Similarity
messages: Belongs to the BACURD family.

8090:LOC101167981
gene id: 8090:LOC101167981
uniprot id: A0A3B3HSB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8090:mcrip2
gene id: 8090:mcrip2
uniprot id: A0A3B3H8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

8090:hopx
gene id: 8090:hopx
uniprot id: A0A3P9L7A3
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101169010
gene id: 8090:LOC101169010
uniprot id: A0A3B3IPZ7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8090:tert
gene id: 8090:tert
uniprot id: A0A140TAW2
uniprot id: Q1PS67
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Catalytic subunit of the telomerase holoenzyme complex composed minimally of TERT and the telomerase RNA template component (TERC).
messages: Expressed at high levels from the embryonic 2-cell stage through to the blastula stage, possibly due to inheritance of maternal transcripts. During later stages levels gradually decline.
messages: Expressed at highest levels in gonads and brain, and at lower levels in heart, spleen, kidney, gill, muscle and skin (PubMed:18312429, PubMed:21547060). Detected in embryonic stem cell lines before and after differentiation (PubMed:21547060). Isoform F is expressed in gonads, with higher levels in testis relative to ovary, but is not detected in other tissues (PubMed:18312429). Isoform B is expressed predominantly in testis (PubMed:21547060). Isoform C is up-regulated in embryonic stem cell lines after differentiation (PubMed:21547060).
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

8090:ctnnb1
gene id: 8090:ctnnb1
uniprot id: A0A3B3HIQ0
uniprot id: A0A3P9LDW4
names: Similarity
messages: Belongs to the beta-catenin family.

8090:LOC101162218
gene id: 8090:LOC101162218
uniprot id: H2LXS6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8090:rb1
gene id: 8090:rb1
uniprot id: A0A3B3HY85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

8090:LOC101175308
gene id: 8090:LOC101175308
uniprot id: A0A3P9LZQ4
uniprot id: H2N1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8090:rnf175
gene id: 8090:rnf175
uniprot id: A0A3P9LJS9
uniprot id: A0A3P9MPX2
uniprot id: H2LBA2
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101163419
gene id: 8090:LOC101163419
uniprot id: H2LL85
names: Subcellular Location Annotation
messages: extracellular matrix

8090:f3
gene id: 8090:f3
uniprot id: H2LGB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

8090:prpf4
gene id: 8090:prpf4
uniprot id: A0A3P9LCX4
uniprot id: H2MZD4
names: Subcellular Location Annotation
messages: Nucleus speckle

8090:LOC101174179
gene id: 8090:LOC101174179
uniprot id: A0A3B3HAQ5
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101155846
gene id: 8090:LOC101155846
uniprot id: A0A3B3HTJ0
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

8090:LOC101159909
gene id: 8090:LOC101159909
uniprot id: A0A3B3HME4
uniprot id: A0A3P9LGI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

8090:rps19bp1
gene id: 8090:rps19bp1
uniprot id: A0A3B3HKB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

8090:sdhd
gene id: 8090:sdhd
uniprot id: H2M2Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

8090:adam19
gene id: 8090:adam19
uniprot id: H2LT74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:thoc7
gene id: 8090:thoc7
uniprot id: A0A3P9IWX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

8090:chmp3
gene id: 8090:chmp3
uniprot id: A0A3P9J2E0
uniprot id: H2MMK3
names: Similarity
messages: Belongs to the SNF7 family.

8090:LOC101171603
gene id: 8090:LOC101171603
uniprot id: H2LP76
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

8090:narfl
gene id: 8090:narfl
uniprot id: H2LZE8
names: Similarity
messages: Belongs to the NARF family.

8090:LOC101173250
gene id: 8090:LOC101173250
uniprot id: H2MHX8
uniprot id: H2MHX9
uniprot id: H2MHY0
names: Similarity
messages: Belongs to the MAP7 family.

8090:LOC101158485
gene id: 8090:LOC101158485
uniprot id: A0A3P9MDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8090:galk2
gene id: 8090:galk2
uniprot id: H2LKD3
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

8090:mstn
gene id: 8090:mstn
uniprot id: D1MYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

8090:LOC101169880
gene id: 8090:LOC101169880
uniprot id: A0A3B3I9M4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:tmem9
gene id: 8090:tmem9
uniprot id: A0A3B3HZE7
names: Similarity
messages: Belongs to the TMEM9 family.

8090:LOC101170345
gene id: 8090:LOC101170345
uniprot id: A0A3B3I504
uniprot id: H2LTK6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:lfng
gene id: 8090:lfng
uniprot id: H2LIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:arpc3
gene id: 8090:arpc3
uniprot id: A0A3B3IKQ5
uniprot id: A0A3P9M4W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

8090:apopt1
gene id: 8090:apopt1
uniprot id: H2MUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COA8 family.
messages: Mitochondrion inner membrane

8090:LOC101173074
gene id: 8090:LOC101173074
uniprot id: A0A3P9ME85
names: Subcellular Location Annotation
messages: Membrane

8090:vdralpha
gene id: 8090:vdralpha
uniprot id: A0A3P9K3U8
uniprot id: B2CCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8090:ccdc22
gene id: 8090:ccdc22
uniprot id: H2MYB1
names: Similarity
messages: Belongs to the CCDC22 family.

8090:gchfr
gene id: 8090:gchfr
uniprot id: A0A3B3IN41
uniprot id: A0A3P9JMC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

8090:med28
gene id: 8090:med28
uniprot id: H2LV36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

8090:LOC101168967
gene id: 8090:LOC101168967
uniprot id: A0A3B3IM10
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:ywhag
gene id: 8090:ywhag
uniprot id: A0A3B3IGC2
uniprot id: A0A3P9I1Q2
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8090:nelfcd
gene id: 8090:nelfcd
uniprot id: A0A3P9JDM6
uniprot id: H2MIJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

8090:LOC101166233
gene id: 8090:LOC101166233
uniprot id: Q8UUM1
names: Similarity
messages: Belongs to the MHC class I family.

8090:LOC101170891
gene id: 8090:LOC101170891
uniprot id: A0A3B3IJ14
names: Subcellular Location Annotation
messages: Cytoplasm

8090:eif3m
gene id: 8090:eif3m
uniprot id: A0A3P9K7C2
uniprot id: H2M1S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8090:LOC101157822
gene id: 8090:LOC101157822
uniprot id: A0A3B3I477
uniprot id: A0A3P9JGR5
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101158765
gene id: 8090:LOC101158765
uniprot id: H2L8F5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8090:LOC101159401
gene id: 8090:LOC101159401
uniprot id: H2M4T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8090:LOC101160902
gene id: 8090:LOC101160902
uniprot id: H2MP56
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8090:LOC101171193
gene id: 8090:LOC101171193
uniprot id: H2MK32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:wdyhv1
gene id: 8090:wdyhv1
uniprot id: H2L881
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

8090:thap1
gene id: 8090:thap1
uniprot id: H2MX13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

8090:ptgs2
gene id: 8090:ptgs2
uniprot id: D3KU78
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101173887
gene id: 8090:LOC101173887
uniprot id: R4N334
names: Similarity
messages: Belongs to the FXYD family.

8090:LOC101165411
gene id: 8090:LOC101165411
uniprot id: H2LJ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8090:LOC101160114
gene id: 8090:LOC101160114
uniprot id: A0A3B3IJ75
uniprot id: A0A3P9KM23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:ndst1
gene id: 8090:ndst1
uniprot id: A0A3P9M8G2
uniprot id: H2LJN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

8090:LOC101173295
gene id: 8090:LOC101173295
uniprot id: A0A3P9ISR6
uniprot id: H2L630
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

8090:spina
gene id: 8090:spina
uniprot id: Q6GWU7
names: Similarity
messages: Belongs to the SPIN/STSY family.

8090:cspg4
gene id: 8090:cspg4
uniprot id: H2L8T3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:mdm2
gene id: 8090:mdm2
uniprot id: H2MRU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Nucleus

8090:LOC101174737
gene id: 8090:LOC101174737
uniprot id: A0A3B3IFU6
names: Similarity
messages: Belongs to the cornifelin family.

8090:btaf1
gene id: 8090:btaf1
uniprot id: H2L508
names: Subcellular Location Annotation
messages: Nucleus

8090:rabggta
gene id: 8090:rabggta
uniprot id: H2L733
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

8090:LOC101158320
gene id: 8090:LOC101158320
uniprot id: A0A3B3H779
uniprot id: A0A3P9JXV0
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

8090:aar2
gene id: 8090:aar2
uniprot id: H2M0R9
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

8090:irf2
gene id: 8090:irf2
uniprot id: H2LXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

8090:LOC101169416
gene id: 8090:LOC101169416
uniprot id: H2N078
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:yrdc
gene id: 8090:yrdc
uniprot id: H2MHD6
names: Similarity
messages: Belongs to the SUA5 family.

8090:dicer1
gene id: 8090:dicer1
uniprot id: H2M5U0
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

8090:LOC101157732
gene id: 8090:LOC101157732
uniprot id: H2LES5
names: Similarity
messages: Belongs to the mab-21 family.

8090:fahd1
gene id: 8090:fahd1
uniprot id: H2LZJ1
names: Similarity
messages: Belongs to the FAH family.

8090:tspan4
gene id: 8090:tspan4
uniprot id: A0A3B3H7F1
uniprot id: A0A3B3HEB2
uniprot id: A0A3P9JWG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC101166883
gene id: 8090:LOC101166883
uniprot id: A0A3B3I836
names: Similarity
messages: Belongs to the IAP family.

8090:LOC111946256
gene id: 8090:LOC111946256
uniprot id: H2LHX1
names: Subcellular Location Annotation
messages: extracellular space

8090:tmem80
gene id: 8090:tmem80
uniprot id: A0A3B3H617
uniprot id: H2LPV2
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101157810
gene id: 8090:LOC101157810
uniprot id: A0A3B3ICA4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

8090:sfpq
gene id: 8090:sfpq
uniprot id: H2LTD3
names: Subcellular Location Annotation
messages: Nucleus speckle

8090:gng4
gene id: 8090:gng4
uniprot id: A0A3B3IHP3
uniprot id: A0A3P9KX67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8090:foxd4
gene id: 8090:foxd4
uniprot id: C1K2Y9
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101157015
gene id: 8090:LOC101157015
uniprot id: H2MCD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:LOC101167883
gene id: 8090:LOC101167883
uniprot id: H2M061
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8090:LOC101167732
gene id: 8090:LOC101167732
uniprot id: H2M813
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

8090:LOC101163534
gene id: 8090:LOC101163534
uniprot id: A0A3B3I6Q8
uniprot id: A0A3P9M9T5
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

8090:emx2
gene id: 8090:emx2
uniprot id: A0A3B3HJ67
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101156794
gene id: 8090:LOC101156794
uniprot id: A0A3B3HSB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101165260
gene id: 8090:LOC101165260
uniprot id: H2MUI0
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

8090:strn4
gene id: 8090:strn4
uniprot id: H2LS00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

8090:ybey
gene id: 8090:ybey
uniprot id: A0A3B3IEV3
uniprot id: A0A3P9HD87
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

8090:LOC101158521
gene id: 8090:LOC101158521
uniprot id: H2LJG8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
messages: Nucleus
messages: Transcription factor.

8090:tnfaip3
gene id: 8090:tnfaip3
uniprot id: A0A3B3H6F5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:LOC101174246
gene id: 8090:LOC101174246
uniprot id: H2LF59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC101158631
gene id: 8090:LOC101158631
uniprot id: H2M380
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:LOC101175090
gene id: 8090:LOC101175090
uniprot id: H2LVP2
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101169498
gene id: 8090:LOC101169498
uniprot id: A0A3P9H6B3
uniprot id: H2MCN1
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8090:irak1bp1
gene id: 8090:irak1bp1
uniprot id: H2M3K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

8090:nudt12
gene id: 8090:nudt12
uniprot id: H2MRF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

8090:bckdha
gene id: 8090:bckdha
uniprot id: H2L9X9
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

8090:zhx2
gene id: 8090:zhx2
uniprot id: H2N2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8090:rpia
gene id: 8090:rpia
uniprot id: A0A3B3HEF7
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

8090:aasdhppt
gene id: 8090:aasdhppt
uniprot id: H2M447
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

8090:stk32a
gene id: 8090:stk32a
uniprot id: A0A3B3H9E8
uniprot id: A0A3B3HLJ4
uniprot id: A0A3P9IXS1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:usp7
gene id: 8090:usp7
uniprot id: A0A3B3I681
names: Similarity
messages: Belongs to the peptidase C19 family.

8090:LOC101166987
gene id: 8090:LOC101166987
uniprot id: H2LAY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

8090:fam207a
gene id: 8090:fam207a
uniprot id: A0A3B3HPH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

8090:LOC101163732
gene id: 8090:LOC101163732
uniprot id: K9L437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

8090:LOC101173279
gene id: 8090:LOC101173279
uniprot id: A0A3P9MNP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101168445
gene id: 8090:LOC101168445
uniprot id: H2N2P1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the type II (or gamma) interferon family.
messages: Isoform A: Widely expressed. Isoform B: Specifically expressed in ovary and testis, with strongest expression in ovary.
messages: Isoform B is up-regulated in response to 17-beta-estradiol (E2).
messages: Probable cytokine.
messages: Secreted

8090:adamts6
gene id: 8090:adamts6
uniprot id: H2L9B4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8090:LOC101173732
gene id: 8090:LOC101173732
uniprot id: A0A3P9HTG0
uniprot id: H2LQ84
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

8090:ntn4
gene id: 8090:ntn4
uniprot id: A0A3B3HT31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:tspo
gene id: 8090:tspo
uniprot id: H2N041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

8090:LOC101162245
gene id: 8090:LOC101162245
uniprot id: A0A3P9M4V4
uniprot id: H2MRN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8090:kdelc1
gene id: 8090:kdelc1
uniprot id: H2N1M5
names: Similarity
messages: Belongs to the KDELC family.

8090:LOC100049345
gene id: 8090:LOC100049345
uniprot id: H2M469
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMN family.
messages: Cajal body
messages: Perikaryon
messages: Z line
messages: gem
messages: neuron projection

8090:hapln1
gene id: 8090:hapln1
uniprot id: A0A3B3HP17
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:hibch
gene id: 8090:hibch
uniprot id: H2MJJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

8090:cygb1
gene id: 8090:cygb1
uniprot id: Q575T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the globin family.
messages: Cytoplasm
messages: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.

8090:med8
gene id: 8090:med8
uniprot id: H2MGQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

8090:egfl6
gene id: 8090:egfl6
uniprot id: A0A3B3HZY9
uniprot id: H2MU23
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:pi4k2a
gene id: 8090:pi4k2a
uniprot id: A0A3P9IVX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

8090:LOC101168872
gene id: 8090:LOC101168872
uniprot id: H2LJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8090:mnep
gene id: 8090:mnep
uniprot id: Q14TH8
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101164166
gene id: 8090:LOC101164166
uniprot id: A0A3B3HEB9
names: Similarity
messages: Belongs to the FAM131 family.

8090:nr4a2
gene id: 8090:nr4a2
uniprot id: H2MQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

8090:cndp2
gene id: 8090:cndp2
uniprot id: H2MY27
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

8090:tcp11
gene id: 8090:tcp11
uniprot id: H2LT20
names: Similarity
messages: Belongs to the TCP11 family.

8090:serpine1
gene id: 8090:serpine1
uniprot id: D7UTX2
names: Similarity
messages: Belongs to the serpin family.

8090:eaf1
gene id: 8090:eaf1
uniprot id: A0A3B3HNY0
uniprot id: A0A3P9H106
names: Similarity
messages: Belongs to the EAF family.

8090:riok3
gene id: 8090:riok3
uniprot id: H2LE55
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

8090:LOC101154996
gene id: 8090:LOC101154996
uniprot id: A0A3B3HS65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8090:rab3ip
gene id: 8090:rab3ip
uniprot id: A0A3B3IC31
uniprot id: A0A3B3IFD2
names: Similarity
messages: Belongs to the SEC2 family.

8090:LOC101163477
gene id: 8090:LOC101163477
uniprot id: H2LHK5
names: Subcellular Location Annotation
messages: extracellular space

8090:lpar6
gene id: 8090:lpar6
uniprot id: W8VSG2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:sft2d3
gene id: 8090:sft2d3
uniprot id: H2LSB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

8090:LOC101157024
gene id: 8090:LOC101157024
uniprot id: A0A3B3IEF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

8090:malrd1
gene id: 8090:malrd1
uniprot id: A0A3B3II86
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:etfrf1
gene id: 8090:etfrf1
uniprot id: A0A3B3HA67
names: Similarity
messages: Belongs to the complex I LYR family.

8090:rpf2
gene id: 8090:rpf2
uniprot id: A0A3P9IUT4
uniprot id: H2MK19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

8090:LOC101161140
gene id: 8090:LOC101161140
uniprot id: H2LQ37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101164419
gene id: 8090:LOC101164419
uniprot id: A0A3B3IC96
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:nhsl2
gene id: 8090:nhsl2
uniprot id: A0A3B3HDU8
uniprot id: A0A3B3INI0
uniprot id: H2M0R3
names: Similarity
messages: Belongs to the NHS family.

8090:mon1a
gene id: 8090:mon1a
uniprot id: H2MH02
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

8090:nlgn3b
gene id: 8090:nlgn3b
uniprot id: A0A3B3HZP9
uniprot id: A0A3P9JZT7
uniprot id: A0A3P9LND4
uniprot id: D2X2I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8090:LOC101173158
gene id: 8090:LOC101173158
uniprot id: A0A3P9I781
uniprot id: H2MHQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

8090:LOC101167413
gene id: 8090:LOC101167413
uniprot id: H2MP63
names: Similarity
messages: Belongs to the mTERF family.

8090:KEF90 p01
gene id: 8090:KEF90_p01
uniprot id: Q8HC78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane

8090:tmem165
gene id: 8090:tmem165
uniprot id: H2L4Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

8090:LOC101155739
gene id: 8090:LOC101155739
uniprot id: A0A3B3IBI4
names: Similarity
messages: Belongs to the isthmin family.

8090:LOC101170876
gene id: 8090:LOC101170876
uniprot id: A0A3B3IJ84
uniprot id: A0A3P9M1S7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

8090:LOC101157155
gene id: 8090:LOC101157155
uniprot id: H2LRG4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101160538
gene id: 8090:LOC101160538
uniprot id: H2L4Y7
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:acad11
gene id: 8090:acad11
uniprot id: H2M363
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8090:zar1
gene id: 8090:zar1
uniprot id: H2L3I5
names: Similarity
messages: Belongs to the ZAR1 family.

8090:mdh1
gene id: 8090:mdh1
uniprot id: A0A3B3IGP1
uniprot id: Q801E8
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

8090:pdss1
gene id: 8090:pdss1
uniprot id: A0A3B3H8L1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

8090:LOC101162380
gene id: 8090:LOC101162380
uniprot id: Q3V628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8090:LOC101159183
gene id: 8090:LOC101159183
uniprot id: H2MRB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101162832
gene id: 8090:LOC101162832
uniprot id: A0A3B3I968
uniprot id: H2MF78
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

8090:stom
gene id: 8090:stom
uniprot id: A0A3P9IL17
uniprot id: H2MAC9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8090:slc29a2
gene id: 8090:slc29a2
uniprot id: H2M601
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

8090:LOC101158913
gene id: 8090:LOC101158913
uniprot id: A0A3P9HMI5
uniprot id: B6F103
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC100301625
gene id: 8090:LOC100301625
uniprot id: H2LJS7
names: Subcellular Location Annotation
messages: Nucleus

8090:foxm1
gene id: 8090:foxm1
uniprot id: A0A3B3HG56
uniprot id: C1K300
names: Subcellular Location Annotation
messages: Nucleus

8090:etfa
gene id: 8090:etfa
uniprot id: H2LUQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

8090:LOC101158848
gene id: 8090:LOC101158848
uniprot id: H2M4A4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

8090:LOC101170407
gene id: 8090:LOC101170407
uniprot id: H2LI87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC101172663
gene id: 8090:LOC101172663
uniprot id: A0A3B3HFJ9
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8090:phf5a
gene id: 8090:phf5a
uniprot id: A0A3P9HCP0
uniprot id: H2LBF5
names: Similarity
messages: Belongs to the PHF5 family.

8090:LOC101167577
gene id: 8090:LOC101167577
uniprot id: H2LDU6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC100873162
gene id: 8090:LOC100873162
uniprot id: H9DV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

8090:LOC101165639
gene id: 8090:LOC101165639
uniprot id: H2L7C5
names: Similarity
messages: Belongs to the FAM83 family.

8090:ighmbp2
gene id: 8090:ighmbp2
uniprot id: H2LQ96
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

8090:LOC101169731
gene id: 8090:LOC101169731
uniprot id: A0A3B3HA25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

8090:rnf20
gene id: 8090:rnf20
uniprot id: H2LIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

8090:LOC101156399
gene id: 8090:LOC101156399
uniprot id: A0A3B3IDM3
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101157001
gene id: 8090:LOC101157001
uniprot id: A0A3B3HT59
uniprot id: A0A3P9LSU4
names: Subcellular Location Annotation
messages: Membrane

8090:usp32
gene id: 8090:usp32
uniprot id: A0A3B3H444
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:1-sf
gene id: 8090:1-sf
uniprot id: Q91184
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8090:LOC101161495
gene id: 8090:LOC101161495
uniprot id: H2MEL1
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8090:LOC101166874
gene id: 8090:LOC101166874
uniprot id: A0A3B3I1D2
uniprot id: A0A3P9M9N1
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

8090:LOC101160576
gene id: 8090:LOC101160576
uniprot id: H2L573
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

8090:LOC101173391
gene id: 8090:LOC101173391
uniprot id: A0A3B3I829
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101161418
gene id: 8090:LOC101161418
uniprot id: H2LJZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8090:LOC101171801
gene id: 8090:LOC101171801
uniprot id: H2L6Y2
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

8090:LOC101170460
gene id: 8090:LOC101170460
uniprot id: A0A3P9L8V2
uniprot id: H2MJK5
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101164062
gene id: 8090:LOC101164062
uniprot id: A0A3B3ICP7
uniprot id: A0A3P9LS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

8090:LOC101162281
gene id: 8090:LOC101162281
uniprot id: H2LKN0
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101171386
gene id: 8090:LOC101171386
uniprot id: A0A3P9KM84
uniprot id: A0A3P9KML3
uniprot id: H2LEE0
uniprot id: H2LEE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

8090:hdac2
gene id: 8090:hdac2
uniprot id: H2MUR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

8090:prdm1b
gene id: 8090:prdm1b
uniprot id: H2MCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

8090:tm9sf3
gene id: 8090:tm9sf3
uniprot id: H2MH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8090:ube2a
gene id: 8090:ube2a
uniprot id: A0A3P9K414
uniprot id: H2L5Q1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:thra
gene id: 8090:thra
uniprot id: A0A3P9JWP3
uniprot id: Q766D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

8090:grm8
gene id: 8090:grm8
uniprot id: H2MDE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8090:pdrg1
gene id: 8090:pdrg1
uniprot id: A0A3B3HES2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

8090:slc6a15
gene id: 8090:slc6a15
uniprot id: H2N0B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:xkr9
gene id: 8090:xkr9
uniprot id: H2LVH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

8090:LOC101157057
gene id: 8090:LOC101157057
uniprot id: A0A3P9MK62
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101157190
gene id: 8090:LOC101157190
uniprot id: H2MWI2
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101173669
gene id: 8090:LOC101173669
uniprot id: H2LXH2
names: Subcellular Location Annotation
messages: Membrane

8090:lhfpl2
gene id: 8090:lhfpl2
uniprot id: A0A3P9IJP3
uniprot id: H2LAQ5
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155804
gene id: 8090:LOC101155804
uniprot id: H2LFA5
names: Subcellular Location Annotation
messages: Membrane

8090:cass4
gene id: 8090:cass4
uniprot id: H2M049
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

8090:LOC101157325
gene id: 8090:LOC101157325
uniprot id: A0A3B3IEP4
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

8090:polr2h
gene id: 8090:polr2h
uniprot id: A0A3B3I5G9
uniprot id: A0A3P9MHH3
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

8090:LOC101157949
gene id: 8090:LOC101157949
uniprot id: A0A3B3HXI5
uniprot id: H2M9R6
names: Subcellular Location Annotation
messages: Membrane

8090:mettl3
gene id: 8090:mettl3
uniprot id: H2LSG5
names: Similarity
messages: Belongs to the MT-A70-like family.

8090:LOC101169059
gene id: 8090:LOC101169059
uniprot id: H2M6L2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8090:LOC101155732
gene id: 8090:LOC101155732
uniprot id: A0A3P9HLF7
uniprot id: H2MUZ7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:LOC101167565
gene id: 8090:LOC101167565
uniprot id: H2MG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

8090:pth2r
gene id: 8090:pth2r
uniprot id: H2MV63
names: Subcellular Location Annotation
messages: Membrane

8090:LOC100533497
gene id: 8090:LOC100533497
uniprot id: E3WET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8090:LOC101173071
gene id: 8090:LOC101173071
uniprot id: A0A3B3IJ38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:tprg1l
gene id: 8090:tprg1l
uniprot id: H2LHZ7
names: Similarity
messages: Belongs to the TPRG1 family.

8090:hoxb9
gene id: 8090:hoxb9
uniprot id: Q3V615
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8090:gde1
gene id: 8090:gde1
uniprot id: A0A3B3I0F9
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8090:dnaaf3
gene id: 8090:dnaaf3
uniprot id: H2LR98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF3 family.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.

8090:LOC101159944
gene id: 8090:LOC101159944
uniprot id: H2MFA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8090:pcsk2
gene id: 8090:pcsk2
uniprot id: H2LPZ0
names: Similarity
messages: Belongs to the peptidase S8 family.

8090:pdcl
gene id: 8090:pdcl
uniprot id: A0A3P9KCT0
uniprot id: H2LK82
names: Similarity
messages: Belongs to the phosducin family.

8090:pdgfra
gene id: 8090:pdgfra
uniprot id: H2MZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:LOC101169695
gene id: 8090:LOC101169695
uniprot id: A0A3B3IH10
names: Subcellular Location Annotation
messages: Nucleus

8090:nudt1
gene id: 8090:nudt1
uniprot id: A0A3B3I653
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus

8090:cdk14
gene id: 8090:cdk14
uniprot id: H2LFI5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:LOC101169782
gene id: 8090:LOC101169782
uniprot id: A0A3B3I411
uniprot id: A0A3P9LV79
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:syngr3
gene id: 8090:syngr3
uniprot id: A0A3P9M329
uniprot id: H2MCV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8090:lipc
gene id: 8090:lipc
uniprot id: H2LW61
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101156840
gene id: 8090:LOC101156840
uniprot id: A0A3B3H660
uniprot id: H2L923
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

8090:LOC101169895
gene id: 8090:LOC101169895
uniprot id: H2MPW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:pter
gene id: 8090:pter
uniprot id: A0A3B3HDQ3
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101166831
gene id: 8090:LOC101166831
uniprot id: A0A3B3HKY4
uniprot id: A0A3B3ILS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8090:mettl15
gene id: 8090:mettl15
uniprot id: H2LN55
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

8090:usp39
gene id: 8090:usp39
uniprot id: A0A3P9MFC1
uniprot id: H2LPG3
names: Subcellular Location Annotation
messages: Nucleus

8090:zc3h12b
gene id: 8090:zc3h12b
uniprot id: H2M0Q5
names: Similarity
messages: Belongs to the ZC3H12 family.

8090:LOC101165410
gene id: 8090:LOC101165410
uniprot id: A0A3P9HCD2
uniprot id: H2L9J9
names: Similarity
messages: Belongs to the cullin family.

8090:opn1sw
gene id: 8090:opn1sw
uniprot id: P87368
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
messages: The three color pigments are found in the cone photoreceptor cells.
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8090:lpcat3
gene id: 8090:lpcat3
uniprot id: H2MB94
names: Subcellular Location Annotation
messages: Membrane

8090:znf592
gene id: 8090:znf592
uniprot id: H2LVC9
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

8090:tmem151b
gene id: 8090:tmem151b
uniprot id: H2M8X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8090:LOC101160874
gene id: 8090:LOC101160874
uniprot id: A0A3B3H8D8
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

8090:ftsj1
gene id: 8090:ftsj1
uniprot id: A0A3B3H689
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

8090:aco1
gene id: 8090:aco1
uniprot id: H2N2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

8090:asic2
gene id: 8090:asic2
uniprot id: A0A3B3I3X9
uniprot id: A0A3P9H5K2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101162835
gene id: 8090:LOC101162835
uniprot id: H2LFI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

8090:evc
gene id: 8090:evc
uniprot id: A0A3B3HT36
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

8090:LOC101169218
gene id: 8090:LOC101169218
uniprot id: H2MFJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:LOC101170226
gene id: 8090:LOC101170226
uniprot id: A0A3B3I4D7
uniprot id: A0A3P9LQL8
uniprot id: A0A3P9LQN5
uniprot id: H2M4M6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8090:acmsd
gene id: 8090:acmsd
uniprot id: H2MV75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

8090:clmp
gene id: 8090:clmp
uniprot id: H2MDZ2
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101162631
gene id: 8090:LOC101162631
uniprot id: A0A3P9M474
uniprot id: H2MRU1
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101155433
gene id: 8090:LOC101155433
uniprot id: A0A3P9KAY6
names: Subcellular Location Annotation
messages: Membrane

8090:mif
gene id: 8090:mif
uniprot id: A0A3P9L3N0
uniprot id: H2LFR8
names: Similarity
messages: Belongs to the MIF family.

8090:LOC101158189
gene id: 8090:LOC101158189
uniprot id: A0A3B3IIU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8090:LOC101156484
gene id: 8090:LOC101156484
uniprot id: A0A3B3HKI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:aplp2
gene id: 8090:aplp2
uniprot id: A0A3B3HL05
uniprot id: A0A3B3HVG6
uniprot id: A0A3B3IL61
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101157651
gene id: 8090:LOC101157651
uniprot id: H2LQC0
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

8090:LOC101173561
gene id: 8090:LOC101173561
uniprot id: H2MGM2
names: Similarity
messages: Belongs to the MARCKS family.

8090:lzic
gene id: 8090:lzic
uniprot id: A0A3B3HSN1
names: Similarity
messages: Belongs to the CTNNBIP1 family.

8090:glrx
gene id: 8090:glrx
uniprot id: A0A3B3I7Q1
uniprot id: A0A3P9IW71
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

8090:LOC101170833
gene id: 8090:LOC101170833
uniprot id: H2MNV2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8090:hsd17b1
gene id: 8090:hsd17b1
uniprot id: H2LGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Favors the reduction of estrogens and androgens. Uses preferentially NADH.

8090:LOC101166093
gene id: 8090:LOC101166093
uniprot id: H2MBC0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8090:LOC101155553
gene id: 8090:LOC101155553
uniprot id: H2MFS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

8090:valop
gene id: 8090:valop
uniprot id: B3Y057
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

8090:LOC101174716
gene id: 8090:LOC101174716
uniprot id: H2MM44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

8090:LOC101163362
gene id: 8090:LOC101163362
uniprot id: A0A3B3HKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8090:LOC101157964
gene id: 8090:LOC101157964
uniprot id: A0A3P9LYM8
uniprot id: H2MKP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8090:gnb5
gene id: 8090:gnb5
uniprot id: A0A3P9H5G2
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8090:nim1k
gene id: 8090:nim1k
uniprot id: H2LGA0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:LOC101174067
gene id: 8090:LOC101174067
uniprot id: A0A3B3HGN9
uniprot id: H2MSK3
names: Similarity
messages: Belongs to the OXR1 family.

8090:med17
gene id: 8090:med17
uniprot id: A0A3B3HJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8090:adam12
gene id: 8090:adam12
uniprot id: H2M1N4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101165235
gene id: 8090:LOC101165235
uniprot id: H2MNP3
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

8090:LOC101175312
gene id: 8090:LOC101175312
uniprot id: H2L8T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:hspa4
gene id: 8090:hspa4
uniprot id: H2LN75
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8090:rspo1
gene id: 8090:rspo1
uniprot id: G0ZE06
names: Similarity
messages: Belongs to the R-spondin family.

8090:cnih2
gene id: 8090:cnih2
uniprot id: A0A3P9LEC2
uniprot id: H2M4M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8090:myf6
gene id: 8090:myf6
uniprot id: H2MNQ1
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8090:LOC101159525
gene id: 8090:LOC101159525
uniprot id: A0A3B3HNF8
uniprot id: A0A3P9IZC1
names: Similarity
messages: Belongs to the calponin family.

8090:LOC101166629
gene id: 8090:LOC101166629
uniprot id: A0A3B3H5G5
uniprot id: A0A3P9IZY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

8090:LOC101168811
gene id: 8090:LOC101168811
uniprot id: A0A3B3I7C8
uniprot id: A0A3P9KJF4
uniprot id: H2LM60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

8090:orla-uaa
gene id: 8090:orla-uaa
uniprot id: Q8UUL6
names: Similarity
messages: Belongs to the MHC class I family.

8090:ppdpf
gene id: 8090:ppdpf
uniprot id: A0A3P9K3X2
uniprot id: H2MVN0
names: Similarity
messages: Belongs to the PPDPF family.

8090:snrpd1
gene id: 8090:snrpd1
uniprot id: A0A3P9JCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

8090:LOC101159690
gene id: 8090:LOC101159690
uniprot id: A0A3B3HVB1
uniprot id: A0A3B3I8D5
uniprot id: A0A3P9ICW5
uniprot id: A0A3P9IDE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:LOC101157953
gene id: 8090:LOC101157953
uniprot id: H2L3R1
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

8090:nbl1
gene id: 8090:nbl1
uniprot id: H2L366
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

8090:hsp70-3
gene id: 8090:hsp70-3
uniprot id: A5HL63
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8090:LOC101171777
gene id: 8090:LOC101171777
uniprot id: H2MKB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

8090:msto1
gene id: 8090:msto1
uniprot id: H2M0D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

8090:nitr22
gene id: 8090:nitr22
uniprot id: B3TZA9
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101169131
gene id: 8090:LOC101169131
uniprot id: A0A3B3HRZ8
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8090:kif13a
gene id: 8090:kif13a
uniprot id: A0A3B3H2L5
uniprot id: H2LVA2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:LOC101170303
gene id: 8090:LOC101170303
uniprot id: H2MJA7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101156850
gene id: 8090:LOC101156850
uniprot id: A0A3B3HMQ0
names: Similarity
messages: Belongs to the SPSB family.

8090:hexb
gene id: 8090:hexb
uniprot id: H2LDW8
uniprot id: H2LDX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

8090:slc49a3
gene id: 8090:slc49a3
uniprot id: H2M5T7
names: Subcellular Location Annotation
messages: Membrane

8090:ctnna1
gene id: 8090:ctnna1
uniprot id: A0A3P9KCF2
uniprot id: H2LSG1
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

8090:LOC101163767
gene id: 8090:LOC101163767
uniprot id: H2LXY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8090:LOC100049335
gene id: 8090:LOC100049335
uniprot id: Q9W7E0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8090:baz1a
gene id: 8090:baz1a
uniprot id: H2M3J4
names: Subcellular Location Annotation
messages: Nucleus

8090:tshz3
gene id: 8090:tshz3
uniprot id: A0A3B3H4I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

8090:atp6v1ba
gene id: 8090:atp6v1ba
uniprot id: A0A3P9LQ46
uniprot id: K0A0D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

8090:rnaseh2a
gene id: 8090:rnaseh2a
uniprot id: H2LGF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

8090:LOC101173152
gene id: 8090:LOC101173152
uniprot id: A0A3P9KV54
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101171995
gene id: 8090:LOC101171995
uniprot id: H2M7F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

8090:LOC101155751
gene id: 8090:LOC101155751
uniprot id: A0A3P9J5N3
uniprot id: H2L6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

8090:actr2
gene id: 8090:actr2
uniprot id: H2LAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
messages: Belongs to the actin family. ARP2 subfamily.
messages: Component of the Arp2/3 complex.
messages: cytoskeleton

8090:acta1
gene id: 8090:acta1
uniprot id: Q98972
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.
messages: In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
messages: Methylated at His-75 by SETD3.
messages: Monomethylation at Lys-86 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.
messages: N-terminal cleavage of acetylated cysteine of intermediate muscle actin by ACTMAP.
messages: Oxidation of Met-46 and Met-49 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promotes actin repolymerization.
messages: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
messages: cytoskeleton

8090:LOC101158891
gene id: 8090:LOC101158891
uniprot id: A0A3B3HPD8
uniprot id: A0A3B3IAX7
uniprot id: A0A3B3II16
names: Subcellular Location Annotation
messages: Membrane

8090:tymp
gene id: 8090:tymp
uniprot id: A0A3B3H840
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Homodimer.

8090:LOC101155909
gene id: 8090:LOC101155909
uniprot id: H2MJ84
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8090:galt
gene id: 8090:galt
uniprot id: H2M8W6
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

8090:LOC101164089
gene id: 8090:LOC101164089
uniprot id: H2LWA3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:errb2
gene id: 8090:errb2
uniprot id: A5HNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8090:gnai3
gene id: 8090:gnai3
uniprot id: P87383
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-alpha family. G(i/o/t/z) subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins (By similarity). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels (By similarity). Required for cortical dynein-dynactin complex recruitment during metaphase (By similarity).
messages: Heterotrimeric G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Part of a spindle orientation complex. Identified in complex with the beta subunit GNB1 and the gamma subunit GNG1. Identified in complex with the beta subunit GNB1 and the gamma subunit GNG2. GTP binding causes dissociation of the heterotrimer, liberating the individual subunits so that they can interact with downstream effector proteins (By similarity).
messages: Membrane
messages: Myristoylation at Gly-2 is required for membrane anchoring before palmitoylation.
messages: Nucleus
messages: Palmitoylation at Cys-3 varies with membrane lipid composition.
messages: cell cortex
messages: centrosome

8090:LOC101156839
gene id: 8090:LOC101156839
uniprot id: A0A3P9L6I6
uniprot id: H2LB72
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8090:ifi30
gene id: 8090:ifi30
uniprot id: H2LWH9
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

8090:LOC101162695
gene id: 8090:LOC101162695
uniprot id: A0A3B3HPS5
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101162818
gene id: 8090:LOC101162818
uniprot id: H2MZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8090:LOC101162366
gene id: 8090:LOC101162366
uniprot id: H2LLD5
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101173884
gene id: 8090:LOC101173884
uniprot id: A0A3P9JX07
uniprot id: H2M0K7
uniprot id: H2M0L4
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8090:ccdc86
gene id: 8090:ccdc86
uniprot id: H2LPH2
names: Subcellular Location Annotation
messages: Nucleus

8090:suz12
gene id: 8090:suz12
uniprot id: A0A3P9M3K8
uniprot id: H2LEJ7
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

8090:LOC101158091
gene id: 8090:LOC101158091
uniprot id: H2LT06
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101158102
gene id: 8090:LOC101158102
uniprot id: H2M3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

8090:hhat
gene id: 8090:hhat
uniprot id: A0A3B3HF35
names: Subcellular Location Annotation
messages: Membrane

8090:specc1l
gene id: 8090:specc1l
uniprot id: A0A3B3I8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

8090:hsp90ab1
gene id: 8090:hsp90ab1
uniprot id: A0A3B3HNE6
names: Similarity
messages: Belongs to the heat shock protein 90 family.

8090:dars
gene id: 8090:dars
uniprot id: A0A3B3H7H5
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

8090:ndfip1
gene id: 8090:ndfip1
uniprot id: H2L7L4
names: Subcellular Location Annotation
messages: Membrane

8090:c3-2
gene id: 8090:c3-2
uniprot id: Q9IBH0
names: Subcellular Location Annotation
messages: Secreted

8090:gpx7
gene id: 8090:gpx7
uniprot id: A0A3B3IKS1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8090:LOC101170632
gene id: 8090:LOC101170632
uniprot id: H2MUB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8090:LOC101174608
gene id: 8090:LOC101174608
uniprot id: A0A3B3HA48
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:pgr
gene id: 8090:pgr
uniprot id: C7G0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8090:LOC101174464
gene id: 8090:LOC101174464
uniprot id: H2MAA7
names: Similarity
messages: Belongs to the ependymin family.

8090:ghrh
gene id: 8090:ghrh
uniprot id: A0A3B3HA91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

8090:LOC101168655
gene id: 8090:LOC101168655
uniprot id: H2LK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

8090:cdk18
gene id: 8090:cdk18
uniprot id: H2M9Q0
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:kdelc2
gene id: 8090:kdelc2
uniprot id: H2MYH8
names: Similarity
messages: Belongs to the KDELC family.

8090:sumf1
gene id: 8090:sumf1
uniprot id: H2MHZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

8090:flt4
gene id: 8090:flt4
uniprot id: C7G0V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:kcnj10
gene id: 8090:kcnj10
uniprot id: H2LBV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:LOC101164651
gene id: 8090:LOC101164651
uniprot id: A0A3B3IIZ7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8090:cat
gene id: 8090:cat
uniprot id: H2L8K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

8090:anxa1
gene id: 8090:anxa1
uniprot id: O93446
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8090:LOC101172731
gene id: 8090:LOC101172731
uniprot id: H2M4H7
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101160244
gene id: 8090:LOC101160244
uniprot id: H2LW28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

8090:LOC101156434
gene id: 8090:LOC101156434
uniprot id: H2MPB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8090:nup85
gene id: 8090:nup85
uniprot id: A0A3B3HIU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

8090:rps7
gene id: 8090:rps7
uniprot id: A0A3P9KWF9
uniprot id: H2MV69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

8090:erg28
gene id: 8090:erg28
uniprot id: A0A3P9HBG5
uniprot id: H2MPM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101163756
gene id: 8090:LOC101163756
uniprot id: A0A3P9LUA7
uniprot id: H2LS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8090:tubg1
gene id: 8090:tubg1
uniprot id: A0A3P9IHD8
uniprot id: H2LHU1
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

8090:LOC101160679
gene id: 8090:LOC101160679
uniprot id: H2LQ30
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8090:pex14
gene id: 8090:pex14
uniprot id: A0A3B3I8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
messages: Peroxisome membrane

8090:fam126b
gene id: 8090:fam126b
uniprot id: A0A3B3HB11
uniprot id: A0A3B3HET0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8090:LOC101157973
gene id: 8090:LOC101157973
uniprot id: A0A3P9IZC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

8090:tp53bp2
gene id: 8090:tp53bp2
uniprot id: A0A3B3HV77
uniprot id: A0A3B3I6Z4
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101167464
gene id: 8090:LOC101167464
uniprot id: H2LR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

8090:ccdc172
gene id: 8090:ccdc172
uniprot id: A0A3B3HCL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC172 family.
messages: Cytoplasm

8090:LOC101169526
gene id: 8090:LOC101169526
uniprot id: A0A3B3HRK9
uniprot id: H2LZW1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC105353532
gene id: 8090:LOC105353532
uniprot id: A0A3P9HD52
uniprot id: H2M0U0
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8090:LOC101173721
gene id: 8090:LOC101173721
uniprot id: H2L9I8
uniprot id: H2L9J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

8090:mns1
gene id: 8090:mns1
uniprot id: H2LX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

8090:LOC101167686
gene id: 8090:LOC101167686
uniprot id: A0A3B3HPG3
names: Subcellular Location Annotation
messages: Membrane

8090:ahcy
gene id: 8090:ahcy
uniprot id: A0A3P9IAP8
uniprot id: H2MC29
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

8090:gpsm2
gene id: 8090:gpsm2
uniprot id: A0A3B3HEF3
uniprot id: H2MLM7
names: Similarity
messages: Belongs to the GPSM family.

8090:LOC101175514
gene id: 8090:LOC101175514
uniprot id: A0A3B3HIN3
names: Similarity
messages: Belongs to the phospholipase D family.

8090:adhfe1
gene id: 8090:adhfe1
uniprot id: H2LR58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

8090:ezh1
gene id: 8090:ezh1
uniprot id: D5MRT8
names: Subcellular Location Annotation
messages: Nucleus

8090:cog8
gene id: 8090:cog8
uniprot id: H2MXB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:foxf2
gene id: 8090:foxf2
uniprot id: A0A3P9IRA2
uniprot id: C1K2Z2
names: Subcellular Location Annotation
messages: Nucleus

8090:stk17b
gene id: 8090:stk17b
uniprot id: A0A3B3IFA5
uniprot id: A0A3P9HA42
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:med22
gene id: 8090:med22
uniprot id: A0A3P9LV21
names: Function
names: Subcellular Location Annotation
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8090:LOC101155744
gene id: 8090:LOC101155744
uniprot id: H2N0Y7
names: Similarity
messages: Belongs to the syntaxin family.

8090:mospd1
gene id: 8090:mospd1
uniprot id: H2M268
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101172501
gene id: 8090:LOC101172501
uniprot id: A0A3B3I3J7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:trpc1
gene id: 8090:trpc1
uniprot id: A0A3P9J970
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

8090:foxd3
gene id: 8090:foxd3
uniprot id: C1K2Y7
names: Subcellular Location Annotation
messages: Nucleus

8090:rspo3
gene id: 8090:rspo3
uniprot id: G0ZE08
names: Similarity
messages: Belongs to the R-spondin family.

8090:trpc4
gene id: 8090:trpc4
uniprot id: H2LGM0
names: Subcellular Location Annotation
messages: Membrane

8090:dpagt1
gene id: 8090:dpagt1
uniprot id: H2LTJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:th
gene id: 8090:th
uniprot id: H2MXJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

8090:map1lc3b
gene id: 8090:map1lc3b
uniprot id: A0A090DC16
uniprot id: A0A3P9MIM4
names: Similarity
messages: Belongs to the ATG8 family.

8090:LOC101163019
gene id: 8090:LOC101163019
uniprot id: H2L7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8090:med6
gene id: 8090:med6
uniprot id: A0A3P9K0P2
uniprot id: H2M0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

8090:LOC101172514
gene id: 8090:LOC101172514
uniprot id: A0A3B3HBS4
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101169311
gene id: 8090:LOC101169311
uniprot id: A0A3P9KXH8
uniprot id: H2MAP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

8090:lrp12
gene id: 8090:lrp12
uniprot id: H2L875
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:ubxn1
gene id: 8090:ubxn1
uniprot id: H2LC34
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC100049513
gene id: 8090:LOC100049513
uniprot id: Q90XN6
names: Subcellular Location Annotation
messages: Nucleus

8090:chmp4b
gene id: 8090:chmp4b
uniprot id: A0A3P9HL84
uniprot id: H2LER3
names: Similarity
messages: Belongs to the SNF7 family.

8090:cnp-1
gene id: 8090:cnp-1
uniprot id: Q8AYR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the natriuretic peptide family.
messages: Brain and spinal cord.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

8090:clic4
gene id: 8090:clic4
uniprot id: A0A3B3INU9
uniprot id: A0A3P9L9H5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8090:LOC101163899
gene id: 8090:LOC101163899
uniprot id: H2M1D5
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

8090:LOC101171820
gene id: 8090:LOC101171820
uniprot id: A0A3P9HZC7
uniprot id: H2MNB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

8090:LOC101161873
gene id: 8090:LOC101161873
uniprot id: H2ME15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

8090:v1ar1
gene id: 8090:v1ar1
uniprot id: H1ADE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:LOC101171658
gene id: 8090:LOC101171658
uniprot id: A0A3B3HAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8090:sgce
gene id: 8090:sgce
uniprot id: A0A3B3HE41
uniprot id: A0A3B3I4Q9
uniprot id: H2LHP1
names: Function
names: Similarity
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.

8090:ptges3
gene id: 8090:ptges3
uniprot id: A0A3B3H294
uniprot id: A0A3P9L834
names: Similarity
messages: Belongs to the p23/wos2 family.

8090:LOC101175353
gene id: 8090:LOC101175353
uniprot id: H2LV74
names: Subcellular Location Annotation
messages: Nucleus

8090:kif18a
gene id: 8090:kif18a
uniprot id: A0A3B3IC03
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:srpx
gene id: 8090:srpx
uniprot id: H2LYS5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC105354227
gene id: 8090:LOC105354227
uniprot id: A0A3B3H7J1
names: Similarity
messages: Belongs to the peptidase C15 family.

8090:trmt44
gene id: 8090:trmt44
uniprot id: H2LNP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

8090:LOC101173935
gene id: 8090:LOC101173935
uniprot id: H2M585
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101170670
gene id: 8090:LOC101170670
uniprot id: A0A3P9H6L8
uniprot id: H2LYN4
names: Similarity
messages: Belongs to the FAM219 family.

8090:rhbdf2
gene id: 8090:rhbdf2
uniprot id: A0A3B3HWD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

8090:cplx4
gene id: 8090:cplx4
uniprot id: A0A3B3IG44
uniprot id: A0A3P9LSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

8090:cdpf1
gene id: 8090:cdpf1
uniprot id: A0A3B3IGW6
names: Similarity
messages: Belongs to the CDPF1 family.

8090:anapc5
gene id: 8090:anapc5
uniprot id: H2MHV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

8090:LOC101175234
gene id: 8090:LOC101175234
uniprot id: H2MCR0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:rfng
gene id: 8090:rfng
uniprot id: H2MHM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:sult4a1
gene id: 8090:sult4a1
uniprot id: A0A3P9MLI2
uniprot id: H2MC99
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:twsg1
gene id: 8090:twsg1
uniprot id: A0A3P9HG82
uniprot id: H2LGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

8090:ccs
gene id: 8090:ccs
uniprot id: H2LVF7
names: Similarity
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.

8090:wdr12
gene id: 8090:wdr12
uniprot id: A0A3B3IP99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

8090:nfkb1
gene id: 8090:nfkb1
uniprot id: A0A3B3HJ55
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:rab11fip3
gene id: 8090:rab11fip3
uniprot id: A0A3B3HMH6
uniprot id: H2LTG3
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

8090:LOC101175508
gene id: 8090:LOC101175508
uniprot id: H2M3I0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

8090:LOC101161104
gene id: 8090:LOC101161104
uniprot id: H2MGE8
names: Similarity
messages: Belongs to the HARBI1 family.

8090:stx12
gene id: 8090:stx12
uniprot id: H2LVJ7
names: Similarity
messages: Belongs to the syntaxin family.

8090:extl2
gene id: 8090:extl2
uniprot id: H2MMV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8090:ddx27
gene id: 8090:ddx27
uniprot id: H2MCT3
names: Similarity
messages: Belongs to the DEAD box helicase family.

8090:atp6v1c1
gene id: 8090:atp6v1c1
uniprot id: H2LD79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

8090:tmtc4
gene id: 8090:tmtc4
uniprot id: H2M640
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8090:rev3l
gene id: 8090:rev3l
uniprot id: H2MJZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

8090:plpp3
gene id: 8090:plpp3
uniprot id: A0A3B3HTQ8
uniprot id: A0A3B3ILE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8090:cpne2
gene id: 8090:cpne2
uniprot id: H2MDH3
names: Similarity
messages: Belongs to the copine family.

8090:LOC100301611
gene id: 8090:LOC100301611
uniprot id: C1K2Z1
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101158710
gene id: 8090:LOC101158710
uniprot id: A0A3P9JB29
uniprot id: H2M9I0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:rprd1b
gene id: 8090:rprd1b
uniprot id: A0A3P9HJL0
uniprot id: H2LG40
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

8090:esrrb
gene id: 8090:esrrb
uniprot id: A0A3B3H673
uniprot id: A0A3P9IXW6
uniprot id: A0A3P9IYB6
uniprot id: A5HNC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8090:cpsf6
gene id: 8090:cpsf6
uniprot id: A0A1S7IWT3
uniprot id: A0A3P9L4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

8090:LOC101162001
gene id: 8090:LOC101162001
uniprot id: A0A3B3IBR3
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101161562
gene id: 8090:LOC101161562
uniprot id: A0A3P9JXY0
uniprot id: H2MG46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

8090:got2
gene id: 8090:got2
uniprot id: H2LYP8
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

8090:LOC101155314
gene id: 8090:LOC101155314
uniprot id: H2MUK1
names: Similarity
messages: Belongs to the AHA1 family.

8090:enpep
gene id: 8090:enpep
uniprot id: A0A3B3IBN4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8090:LOC101168369
gene id: 8090:LOC101168369
uniprot id: H2LTA5
names: Similarity
messages: Belongs to the SNF7 family.

8090:eef1g
gene id: 8090:eef1g
uniprot id: H2LD99
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

8090:LOC101172093
gene id: 8090:LOC101172093
uniprot id: H2M3T4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8090:jag1
gene id: 8090:jag1
uniprot id: H2M9P8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8090:LOC101175698
gene id: 8090:LOC101175698
uniprot id: H2MIR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:lsm14a
gene id: 8090:lsm14a
uniprot id: A0A6F8PDR9
names: Similarity
messages: Belongs to the LSM14 family.

8090:LOC101161483
gene id: 8090:LOC101161483
uniprot id: A0A3B3HQ62
uniprot id: A0A3B3I9A8
names: Similarity
messages: Belongs to the BicD family.

8090:usp14
gene id: 8090:usp14
uniprot id: A0A3P9KDR5
uniprot id: H2MTG5
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

8090:parp1
gene id: 8090:parp1
uniprot id: H2MF09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

8090:man1c1
gene id: 8090:man1c1
uniprot id: A0A3P9MIT5
uniprot id: H2MJ11
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8090:LOC101165720
gene id: 8090:LOC101165720
uniprot id: H2MC48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8090:LOC101166143
gene id: 8090:LOC101166143
uniprot id: A0A3B3IF91
uniprot id: A0A3P9KML1
names: Similarity
messages: Belongs to the TGF-beta family.

8090:LOC101160178
gene id: 8090:LOC101160178
uniprot id: A0A3B3HBM2
uniprot id: A0A3B3HZ07
uniprot id: H2MAN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

8090:psmb2
gene id: 8090:psmb2
uniprot id: A0A3P9HJ14
uniprot id: H2M1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8090:LOC101166168
gene id: 8090:LOC101166168
uniprot id: H2MUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

8090:LOC101165662
gene id: 8090:LOC101165662
uniprot id: A0A3B3ILL7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

8090:LOC101160579
gene id: 8090:LOC101160579
uniprot id: A0A3B3IH67
uniprot id: A0A3P9J874
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8090:LOC105356005
gene id: 8090:LOC105356005
uniprot id: A0A3B3I662
names: Subcellular Location Annotation
messages: Membrane

8090:ppfibp1
gene id: 8090:ppfibp1
uniprot id: A0A3B3HQT4
uniprot id: A0A3B3I075
uniprot id: H2M5S9
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

8090:slc37a2
gene id: 8090:slc37a2
uniprot id: H2MH29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8090:anapc15
gene id: 8090:anapc15
uniprot id: A0A3B3H605
uniprot id: A0A3P9IP27
names: Similarity
messages: Belongs to the APC15 family.

8090:kifc1
gene id: 8090:kifc1
uniprot id: H2LRE2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:LOC101168495
gene id: 8090:LOC101168495
uniprot id: A0A3B3I9V8
names: Similarity
messages: Belongs to the peptidase C19 family.

8090:efhb
gene id: 8090:efhb
uniprot id: A0A3B3IMR2
names: Subcellular Location Annotation
messages: cilium axoneme

8090:kif6
gene id: 8090:kif6
uniprot id: H2MTZ6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:LOC101174623
gene id: 8090:LOC101174623
uniprot id: H2M313
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

8090:apex1
gene id: 8090:apex1
uniprot id: A0A3P9IG23
uniprot id: H2MAE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

8090:pfkfb1
gene id: 8090:pfkfb1
uniprot id: H2MNU0
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8090:bcas2
gene id: 8090:bcas2
uniprot id: A0A3B3I523
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

8090:LOC101157151
gene id: 8090:LOC101157151
uniprot id: H2MCR6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8090:LOC110013322
gene id: 8090:LOC110013322
uniprot id: H2LX58
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:slc35a5
gene id: 8090:slc35a5
uniprot id: H2ME45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8090:tmem39b
gene id: 8090:tmem39b
uniprot id: H2MRS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

8090:LOC101164881
gene id: 8090:LOC101164881
uniprot id: H2MLG4
names: Similarity
messages: Belongs to the TPRG1 family.

8090:adipor1
gene id: 8090:adipor1
uniprot id: A0A3P9HYP7
uniprot id: H2MIS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8090:LOC101158978
gene id: 8090:LOC101158978
uniprot id: H2LAN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8090:atp6v1h
gene id: 8090:atp6v1h
uniprot id: H2MU55
uniprot id: H2MU57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8090:LOC101157960
gene id: 8090:LOC101157960
uniprot id: A0A3B3I060
uniprot id: H2LUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8090:LOC101172220
gene id: 8090:LOC101172220
uniprot id: H2N129
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8090:LOC101174843
gene id: 8090:LOC101174843
uniprot id: H2LVM6
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:tph1
gene id: 8090:tph1
uniprot id: I4DDB1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8090:idi1
gene id: 8090:idi1
uniprot id: H2LJU9
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

8090:LOC101165374
gene id: 8090:LOC101165374
uniprot id: A0A3P9MF16
uniprot id: H2L744
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:pold1
gene id: 8090:pold1
uniprot id: H2M6Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

8090:KEF90 p06
gene id: 8090:KEF90_p06
uniprot id: Q8HLW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

8090:cd63
gene id: 8090:cd63
uniprot id: A0A3P9KP60
uniprot id: H2MK80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:akr1a1
gene id: 8090:akr1a1
uniprot id: H2MH62
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8090:esr2
gene id: 8090:esr2
uniprot id: B1B6T4
uniprot id: Q8UW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8090:LOC101174130
gene id: 8090:LOC101174130
uniprot id: H2M0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8090:LOC101165233
gene id: 8090:LOC101165233
uniprot id: H2M1Q2
names: Subcellular Location Annotation
messages: Membrane

8090:snx18
gene id: 8090:snx18
uniprot id: H2L904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8090:LOC101163256
gene id: 8090:LOC101163256
uniprot id: H2MH87
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8090:shpk
gene id: 8090:shpk
uniprot id: H2M7C5
names: Similarity
messages: Belongs to the FGGY kinase family.

8090:LOC101174248
gene id: 8090:LOC101174248
uniprot id: A0A3B3IDL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:pfkl
gene id: 8090:pfkl
uniprot id: A0A3B3IF63
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:trabd2a
gene id: 8090:trabd2a
uniprot id: A0A3B3I6T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

8090:thbs1
gene id: 8090:thbs1
uniprot id: C5HIF4
uniprot id: H2MQR9
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:acer1
gene id: 8090:acer1
uniprot id: H2LZH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:kit
gene id: 8090:kit
uniprot id: A0A3B3HC84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:c7h1orf174
gene id: 8090:c7h1orf174
uniprot id: A0A3B3IGW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

8090:LOC101164585
gene id: 8090:LOC101164585
uniprot id: H2LKQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8090:znrd1
gene id: 8090:znrd1
uniprot id: A0A3B3H5H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: nucleolus

8090:LOC101159619
gene id: 8090:LOC101159619
uniprot id: A0A3B3H7Y7
uniprot id: A0A3B3HRH6
names: Similarity
messages: Belongs to the peptidase C2 family.

8090:rad52
gene id: 8090:rad52
uniprot id: H2M428
names: Similarity
messages: Belongs to the RAD52 family.

8090:LOC101159112
gene id: 8090:LOC101159112
uniprot id: A0A3B3HMT7
uniprot id: A0A3P9I9H8
names: Similarity
messages: Belongs to the ATG8 family.

8090:ddx56
gene id: 8090:ddx56
uniprot id: H2L7F9
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8090:LOC101155558
gene id: 8090:LOC101155558
uniprot id: A0A3B3HDJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

8090:yipf1
gene id: 8090:yipf1
uniprot id: H2N2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

8090:LOC101169638
gene id: 8090:LOC101169638
uniprot id: H2MMX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted

8090:LOC101161944
gene id: 8090:LOC101161944
uniprot id: A0A3B3HWC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

8090:cant1
gene id: 8090:cant1
uniprot id: H2LUG5
names: Similarity
messages: Belongs to the apyrase family.

8090:neu4
gene id: 8090:neu4
uniprot id: H2LPW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8090:psmd13
gene id: 8090:psmd13
uniprot id: H2L2Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

8090:LOC101155037
gene id: 8090:LOC101155037
uniprot id: A0A3P9LCU1
uniprot id: H2LAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

8090:rpe65
gene id: 8090:rpe65
uniprot id: A0A3P9KJ62
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8090:LOC101166217
gene id: 8090:LOC101166217
uniprot id: H2LNF9
names: Similarity
messages: Belongs to the RBR family.

8090:clcn5
gene id: 8090:clcn5
uniprot id: A0A3B3HC99
uniprot id: A0A3B3HK89
uniprot id: H2LXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

8090:tes
gene id: 8090:tes
uniprot id: H2MZP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

8090:LOC101166154
gene id: 8090:LOC101166154
uniprot id: A0A3B3HIA9
uniprot id: A0A3P9J9I6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:znf703
gene id: 8090:znf703
uniprot id: H2MLA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

8090:syndig1l
gene id: 8090:syndig1l
uniprot id: A0A3P9H8P1
uniprot id: H2MQ70
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8090:rpl27
gene id: 8090:rpl27
uniprot id: A0A3P9HDH9
uniprot id: H2L7U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

8090:lig4
gene id: 8090:lig4
uniprot id: H2LGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

8090:LOC101171732
gene id: 8090:LOC101171732
uniprot id: A0A3B3IEY6
names: Subcellular Location Annotation
messages: Membrane

8090:sin3b
gene id: 8090:sin3b
uniprot id: A0A3B3HLU2
names: Subcellular Location Annotation
messages: Nucleus

8090:swi5
gene id: 8090:swi5
uniprot id: A0A3B3IDH1
names: Function
names: Similarity
messages: Belongs to the SWI5/SAE3 family.
messages: Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.

8090:cnr1
gene id: 8090:cnr1
uniprot id: H2M796
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids. Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues. Signaling typically involves reduction in cyclic AMP.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

8090:LOC101169392
gene id: 8090:LOC101169392
uniprot id: A0A3B3ICH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8090:LOC101166490
gene id: 8090:LOC101166490
uniprot id: H2MJL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:pigh
gene id: 8090:pigh
uniprot id: A0A3B3H411
uniprot id: A0A3P9JAF1
names: Similarity
messages: Belongs to the PIGH family.

8090:LOC101159926
gene id: 8090:LOC101159926
uniprot id: H2LLF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

8090:nudcd1
gene id: 8090:nudcd1
uniprot id: H2LV53
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:dnm1
gene id: 8090:dnm1
uniprot id: A0A3B3H8X4
uniprot id: A0A3B3HDL2
uniprot id: A0A3B3HK48
uniprot id: A0A3P9LDY4
uniprot id: A0A3P9LEA9
uniprot id: A0A3P9ML77
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

8090:eif3e
gene id: 8090:eif3e
uniprot id: A0A3P9LLU4
uniprot id: H2N2G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

8090:LOC101161443
gene id: 8090:LOC101161443
uniprot id: A0A3B3IGT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

8090:dctn5
gene id: 8090:dctn5
uniprot id: A0A3P9JTJ0
uniprot id: H2MBX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

8090:acsl3
gene id: 8090:acsl3
uniprot id: H2LZI3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8090:LOC101167626
gene id: 8090:LOC101167626
uniprot id: H2MQ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8090:LOC101173968
gene id: 8090:LOC101173968
uniprot id: H2LHS0
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101167620
gene id: 8090:LOC101167620
uniprot id: A0A3B3I880
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:msh6
gene id: 8090:msh6
uniprot id: H2M605
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

8090:opgb
gene id: 8090:opgb
uniprot id: F5CIT9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101155527
gene id: 8090:LOC101155527
uniprot id: H2LLM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:cpeb1
gene id: 8090:cpeb1
uniprot id: H2L7Q2
names: Similarity
messages: Belongs to the RRM CPEB family.

8090:amdhd2
gene id: 8090:amdhd2
uniprot id: H2L6W9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

8090:tm2d2
gene id: 8090:tm2d2
uniprot id: H2MNS2
names: Subcellular Location Annotation
messages: Membrane

8090:hspd1
gene id: 8090:hspd1
uniprot id: H2N305
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

8090:fkrp
gene id: 8090:fkrp
uniprot id: H2LRX2
names: Similarity
messages: Belongs to the LicD transferase family.

8090:mfsd9
gene id: 8090:mfsd9
uniprot id: A0A3B3HQ83
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101162919
gene id: 8090:LOC101162919
uniprot id: A0A3B3HU92
uniprot id: H2MKV8
uniprot id: H2MKW0
names: Similarity
messages: Belongs to the MAGUK family.

8090:serpinh1
gene id: 8090:serpinh1
uniprot id: A0A3B3HQ98
uniprot id: H2MH48
names: Similarity
messages: Belongs to the serpin family.

8090:LOC101155122
gene id: 8090:LOC101155122
uniprot id: H2LW03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101154931
gene id: 8090:LOC101154931
uniprot id: A0A3P9ICW4
uniprot id: H2MEM6
names: Subcellular Location Annotation
messages: extracellular space

8090:pgls
gene id: 8090:pgls
uniprot id: H2LQJ1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

8090:tac1
gene id: 8090:tac1
uniprot id: B7XB94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

8090:svop
gene id: 8090:svop
uniprot id: A0A3P9MC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

8090:hacd2
gene id: 8090:hacd2
uniprot id: A0A3P9IFX5
uniprot id: H2M1A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:pxmp2
gene id: 8090:pxmp2
uniprot id: H2LS96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8090:LOC101172160
gene id: 8090:LOC101172160
uniprot id: H2L4R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

8090:trhr2
gene id: 8090:trhr2
uniprot id: E5RNC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

8090:mrps2
gene id: 8090:mrps2
uniprot id: H2LF07
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

8090:bud31
gene id: 8090:bud31
uniprot id: A0A3P9IEF0
uniprot id: H2MFE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

8090:LOC101159072
gene id: 8090:LOC101159072
uniprot id: A0A3P9KLN3
uniprot id: H2LET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8090:c16h8orf37
gene id: 8090:c16h8orf37
uniprot id: A0A3B3IFI3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

8090:six2
gene id: 8090:six2
uniprot id: H2LHU6
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101155504
gene id: 8090:LOC101155504
uniprot id: H2MBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

8090:LOC101161003
gene id: 8090:LOC101161003
uniprot id: H2M665
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

8090:cenpm
gene id: 8090:cenpm
uniprot id: A0A3B3HDA4
uniprot id: A0A3P9M1W6
names: Subcellular Location Annotation
messages: Nucleus

8090:slc46a2
gene id: 8090:slc46a2
uniprot id: H2M7V0
names: Subcellular Location Annotation
messages: Membrane

8090:pttg1
gene id: 8090:pttg1
uniprot id: H2L604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

8090:ddx10
gene id: 8090:ddx10
uniprot id: H2LD36
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8090:LOC101155172
gene id: 8090:LOC101155172
uniprot id: A0A3B3HZ09
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101170553
gene id: 8090:LOC101170553
uniprot id: H2MPF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP.
messages: Nucleus
messages: lamellipodium
messages: ruffle

8090:LOC101172145
gene id: 8090:LOC101172145
uniprot id: A0A3B3ILQ2
names: Subcellular Location Annotation
messages: Membrane

8090:rcl1
gene id: 8090:rcl1
uniprot id: H2M3S5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.
messages: nucleolus

8090:LOC101168823
gene id: 8090:LOC101168823
uniprot id: H2M1W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8090:gpr39
gene id: 8090:gpr39
uniprot id: A0A3B3IFJ0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:LOC101171811
gene id: 8090:LOC101171811
uniprot id: H2LEV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8090:LOC101169635
gene id: 8090:LOC101169635
uniprot id: H2LNX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

8090:ddx43
gene id: 8090:ddx43
uniprot id: H2LAA7
names: Similarity
messages: Belongs to the DEAD box helicase family.

8090:ppp1r16b
gene id: 8090:ppp1r16b
uniprot id: H2LLT7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:sh2b2
gene id: 8090:sh2b2
uniprot id: H2LPP1
names: Similarity
messages: Belongs to the SH2B adapter family.

8090:slc9a6
gene id: 8090:slc9a6
uniprot id: H2L7V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

8090:LOC101167938
gene id: 8090:LOC101167938
uniprot id: H2N0S4
uniprot id: H2N0S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

8090:kif19
gene id: 8090:kif19
uniprot id: H2M5Q9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:snx9
gene id: 8090:snx9
uniprot id: A0A3B3H775
uniprot id: A0A3B3HHE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

8090:birc7
gene id: 8090:birc7
uniprot id: A0A3B3HWJ5
names: Similarity
messages: Belongs to the IAP family.

8090:LOC101157139
gene id: 8090:LOC101157139
uniprot id: A0A3P9JKA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

8090:LOC101165641
gene id: 8090:LOC101165641
uniprot id: H2LQT9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:entpd2
gene id: 8090:entpd2
uniprot id: H2MGK5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

8090:LOC101169564
gene id: 8090:LOC101169564
uniprot id: A0A3B3HPC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
messages: Membrane

8090:rpl17
gene id: 8090:rpl17
uniprot id: A0A3B3HUE9
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

8090:LOC101168229
gene id: 8090:LOC101168229
uniprot id: H2LWJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:LOC101163984
gene id: 8090:LOC101163984
uniprot id: H2MRK2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8090:e2f4
gene id: 8090:e2f4
uniprot id: H2MLT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8090:fh
gene id: 8090:fh
uniprot id: H2MR31
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

8090:myf5
gene id: 8090:myf5
uniprot id: H2MNP6
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8090:lrrc4b
gene id: 8090:lrrc4b
uniprot id: A0A3P9HC45
uniprot id: H2L934
names: Subcellular Location Annotation
messages: Membrane

8090:LOC105355489
gene id: 8090:LOC105355489
uniprot id: H2M961
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8090:prdm13
gene id: 8090:prdm13
uniprot id: H2L9U6
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101171139
gene id: 8090:LOC101171139
uniprot id: H2M3P0
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

8090:LOC101172782
gene id: 8090:LOC101172782
uniprot id: A0A3B3INU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

8090:jmy
gene id: 8090:jmy
uniprot id: H2LAX2
names: Subcellular Location Annotation
messages: Membrane

8090:olgc2
gene id: 8090:olgc2
uniprot id: Q9PWG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8090:LOC101155811
gene id: 8090:LOC101155811
uniprot id: A0A3P9I2U0
uniprot id: H2MDU5
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

8090:olfml2a
gene id: 8090:olfml2a
uniprot id: A0A3B3HVM9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:fam163b
gene id: 8090:fam163b
uniprot id: A0A3B3ID99
uniprot id: A0A3P9J128
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

8090:ablim3
gene id: 8090:ablim3
uniprot id: H2LTU3
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101165526
gene id: 8090:LOC101165526
uniprot id: H2MSF6
names: Similarity
messages: Belongs to the peptidase C1 family.

8090:LOC101158949
gene id: 8090:LOC101158949
uniprot id: A0A3B3HA31
uniprot id: H2MNP5
names: Similarity
messages: Belongs to the ubinuclein family.

8090:LOC101167390
gene id: 8090:LOC101167390
uniprot id: H2LP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

8090:mep1b
gene id: 8090:mep1b
uniprot id: H2MS16
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:amfr
gene id: 8090:amfr
uniprot id: A0A3B3H9T4
names: Subcellular Location Annotation
messages: Membrane

8090:mgmt
gene id: 8090:mgmt
uniprot id: A0A3B3HBV6
uniprot id: A0A3P9HZ00
names: Similarity
messages: Belongs to the MGMT family.

8090:LOC101163354
gene id: 8090:LOC101163354
uniprot id: A0A3B3H9M1
uniprot id: A0A3P9IG80
names: Similarity
messages: Belongs to the stathmin family.

8090:tpk1
gene id: 8090:tpk1
uniprot id: A0A3B3IKR1
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

8090:fdxr
gene id: 8090:fdxr
uniprot id: H2N1E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

8090:lap3
gene id: 8090:lap3
uniprot id: H2LV22
names: Similarity
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Homohexamer.

8090:wars
gene id: 8090:wars
uniprot id: H2MHT6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8090:alkbh1
gene id: 8090:alkbh1
uniprot id: H2M4V7
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

8090:LOC101164411
gene id: 8090:LOC101164411
uniprot id: A0A3B3H9E3
uniprot id: A0A3P9I825
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8090:adgrd2
gene id: 8090:adgrd2
uniprot id: A0A3B3HXQ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:zgpat
gene id: 8090:zgpat
uniprot id: H2L5J8
names: Subcellular Location Annotation
messages: Nucleus

8090:chd9
gene id: 8090:chd9
uniprot id: A0A3B3HY92
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

8090:LOC101167624
gene id: 8090:LOC101167624
uniprot id: A0A3B3HL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

8090:ift43
gene id: 8090:ift43
uniprot id: A0A3B3IA28
names: Similarity
messages: Belongs to the IFT43 family.

8090:LOC101162519
gene id: 8090:LOC101162519
uniprot id: H2LKN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:mphosph10
gene id: 8090:mphosph10
uniprot id: H2LMS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

8090:rpl35
gene id: 8090:rpl35
uniprot id: A0A3P9JEF4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

8090:cwf19l2
gene id: 8090:cwf19l2
uniprot id: H2M3Y3
names: Similarity
messages: Belongs to the CWF19 family.

8090:LOC101167184
gene id: 8090:LOC101167184
uniprot id: H2LH46
names: Subcellular Location Annotation
messages: Nucleus speckle

8090:cd74
gene id: 8090:cd74
uniprot id: H2LJJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101163471
gene id: 8090:LOC101163471
uniprot id: A0A3B3HS64
names: Similarity
messages: Belongs to the peptidase M14 family.

8090:LOC101168152
gene id: 8090:LOC101168152
uniprot id: A0A3P9KTS6
uniprot id: H2LYJ4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8090:ehhadh
gene id: 8090:ehhadh
uniprot id: H2MPH3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

8090:LOC101165147
gene id: 8090:LOC101165147
uniprot id: H2LS51
names: Similarity
messages: Belongs to the UPF0585 family.

8090:LOC101158514
gene id: 8090:LOC101158514
uniprot id: H2M5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8090:kras
gene id: 8090:kras
uniprot id: A0A3P9LH79
uniprot id: O42277
uniprot id: O57467
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Cell membrane
messages: Cytoplasm
messages: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.

8090:hspb6
gene id: 8090:hspb6
uniprot id: A0A3B3I3S2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8090:LOC101172853
gene id: 8090:LOC101172853
uniprot id: H2MDJ7
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

8090:tbrg1
gene id: 8090:tbrg1
uniprot id: H2MHT1
names: Subcellular Location Annotation
messages: Nucleus

8090:vsx2
gene id: 8090:vsx2
uniprot id: Q9I9A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator (By similarity). Mediates the differentiation of V2a interneurons (By similarity). Plays a role in eye development and organization of the neuroretina (By similarity).
messages: Belongs to the paired homeobox family.
messages: Nucleus

8090:LOC101170646
gene id: 8090:LOC101170646
uniprot id: A0A3P9I5H1
uniprot id: H2L385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:nid2
gene id: 8090:nid2
uniprot id: H2LFW9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

8090:lin9
gene id: 8090:lin9
uniprot id: A0A3P9M7A4
uniprot id: H2MF67
names: Similarity
messages: Belongs to the lin-9 family.

8090:qsox1
gene id: 8090:qsox1
uniprot id: H2MSG5
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

8090:LOC101166509
gene id: 8090:LOC101166509
uniprot id: H2LTT9
uniprot id: H2LTU2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:LOC101159828
gene id: 8090:LOC101159828
uniprot id: H2LF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8090:alg2
gene id: 8090:alg2
uniprot id: H2LXS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

8090:cyp11b
gene id: 8090:cyp11b
uniprot id: Q76EY4
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:atp2b3
gene id: 8090:atp2b3
uniprot id: A0A3B3HD88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:cyp17
gene id: 8090:cyp17
uniprot id: P70085
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
messages: Membrane

8090:LOC101168881
gene id: 8090:LOC101168881
uniprot id: H2LJP8
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101165247
gene id: 8090:LOC101165247
uniprot id: A0A3B3IEE4
uniprot id: A0A3P9K2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

8090:LOC101160321
gene id: 8090:LOC101160321
uniprot id: H2L5V0
names: Subcellular Location Annotation
messages: Nucleus

8090:tprkb
gene id: 8090:tprkb
uniprot id: A0A3B3H6N3
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

8090:LOC101160640
gene id: 8090:LOC101160640
uniprot id: H2MD66
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101162318
gene id: 8090:LOC101162318
uniprot id: A0A3B3IKI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

8090:LOC101168159
gene id: 8090:LOC101168159
uniprot id: A0A3B3H5J3
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

8090:LOC101157703
gene id: 8090:LOC101157703
uniprot id: H2LD17
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

8090:mrpl24
gene id: 8090:mrpl24
uniprot id: A0A3P9J5E8
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

8090:slc13a1
gene id: 8090:slc13a1
uniprot id: H2L368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8090:ficd
gene id: 8090:ficd
uniprot id: H2LRD7
names: Similarity
messages: Belongs to the fic family.

8090:sstr2
gene id: 8090:sstr2
uniprot id: H2LV73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

8090:alas1
gene id: 8090:alas1
uniprot id: H2LJ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

8090:LOC101155031
gene id: 8090:LOC101155031
uniprot id: A0A3B3H3H9
uniprot id: A0A3P9J5G8
uniprot id: H2LW66
names: Similarity
messages: Belongs to the TIM16/PAM16 family.
messages: Belongs to the WD repeat coronin family.

8090:eif3l
gene id: 8090:eif3l
uniprot id: H2MEA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8090:magi1
gene id: 8090:magi1
uniprot id: A0A3B3HMF7
names: Subcellular Location Annotation
messages: Membrane

8090:aqp4
gene id: 8090:aqp4
uniprot id: H2MRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8090:KEF90 p11
gene id: 8090:KEF90_p11
uniprot id: Q8HLX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

8090:trappc2l
gene id: 8090:trappc2l
uniprot id: A0A3P9HYI1
uniprot id: H2LLP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

8090:LOC101172196
gene id: 8090:LOC101172196
uniprot id: H2LLM2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8090:LOC101168347
gene id: 8090:LOC101168347
uniprot id: H2N295
names: Similarity
messages: Belongs to the CD99 family.

8090:stx19
gene id: 8090:stx19
uniprot id: H2MLI6
names: Similarity
messages: Belongs to the syntaxin family.

8090:pigw
gene id: 8090:pigw
uniprot id: H2M6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

8090:LOC101173001
gene id: 8090:LOC101173001
uniprot id: H2M999
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8090:LOC101166604
gene id: 8090:LOC101166604
uniprot id: H2L3H4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:cyld
gene id: 8090:cyld
uniprot id: H2MFL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

8090:LOC101168278
gene id: 8090:LOC101168278
uniprot id: A0A3B3I197
names: Subcellular Location Annotation
messages: Membrane

8090:atp5f1b
gene id: 8090:atp5f1b
uniprot id: A0A3P9LG46
uniprot id: H2LEL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

8090:gins1
gene id: 8090:gins1
uniprot id: H2LC13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

8090:LOC101161368
gene id: 8090:LOC101161368
uniprot id: H2N0W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8090:LOC101157800
gene id: 8090:LOC101157800
uniprot id: A0A3P9K015
uniprot id: H2LX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

8090:fabp2
gene id: 8090:fabp2
uniprot id: A0A3B3IIS9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:LOC101173404
gene id: 8090:LOC101173404
uniprot id: A0A3B3IB18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

8090:zer1
gene id: 8090:zer1
uniprot id: A0A3B3IH56
names: Similarity
messages: Belongs to the zyg-11 family.

8090:LOC101172108
gene id: 8090:LOC101172108
uniprot id: H2MMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

8090:polr2k
gene id: 8090:polr2k
uniprot id: A0A3P9J737
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

8090:lrrc4c
gene id: 8090:lrrc4c
uniprot id: A0A3P9H381
uniprot id: H2L5W9
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101166126
gene id: 8090:LOC101166126
uniprot id: H2MPF1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:plcg1
gene id: 8090:plcg1
uniprot id: A0A3B3HGN5
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

8090:LOC101156106
gene id: 8090:LOC101156106
uniprot id: H2MIN2
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:scmh1
gene id: 8090:scmh1
uniprot id: H2MGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

8090:LOC101170509
gene id: 8090:LOC101170509
uniprot id: A0A3B3I0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

8090:LOC101159157
gene id: 8090:LOC101159157
uniprot id: A0A3B3IJZ1
uniprot id: A0A3P9LIG2
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8090:LOC101163089
gene id: 8090:LOC101163089
uniprot id: H2M2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

8090:ccdc34
gene id: 8090:ccdc34
uniprot id: A0A3B3H2J2
names: Subcellular Location Annotation
messages: flagellum

8090:LOC101163554
gene id: 8090:LOC101163554
uniprot id: H2LEC5
names: Subcellular Location Annotation
messages: Membrane

8090:sfrp5
gene id: 8090:sfrp5
uniprot id: H2LTX7
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:ncan
gene id: 8090:ncan
uniprot id: H2L5F5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:fgf8
gene id: 8090:fgf8
uniprot id: A0A3B3IEJ6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8090:LOC101156079
gene id: 8090:LOC101156079
uniprot id: A0A3B3H3P5
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

8090:rapgef6
gene id: 8090:rapgef6
uniprot id: A0A3B3IC67
uniprot id: H2L671
names: Similarity
messages: Belongs to the RAPGEF2 family.

8090:LOC101172557
gene id: 8090:LOC101172557
uniprot id: A0A3P9H838
uniprot id: H2M6X1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8090:grwd1
gene id: 8090:grwd1
uniprot id: H2M6R7
names: Subcellular Location Annotation
messages: Nucleus

8090:pggt1b
gene id: 8090:pggt1b
uniprot id: H2LJK2
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

8090:LOC101172257
gene id: 8090:LOC101172257
uniprot id: H2M3V2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8090:piwil2
gene id: 8090:piwil2
uniprot id: B9U224
names: Similarity
messages: Belongs to the argonaute family.

8090:LOC101158844
gene id: 8090:LOC101158844
uniprot id: H2MAP3
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

8090:shh
gene id: 8090:shh
uniprot id: A0A3B3H8Y2
uniprot id: A0A3P9M3Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

8090:LOC101170468
gene id: 8090:LOC101170468
uniprot id: H2LCU1
names: Similarity
messages: Belongs to the globin family.

8090:gabpa
gene id: 8090:gabpa
uniprot id: H2LYC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:LOC101165141
gene id: 8090:LOC101165141
uniprot id: A0A3B3HMJ1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:LOC101171158
gene id: 8090:LOC101171158
uniprot id: A0A3P9J6E6
uniprot id: H2LPX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:rrp36
gene id: 8090:rrp36
uniprot id: A0A3B3HJ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

8090:vit-6
gene id: 8090:vit-6
uniprot id: Q8UW61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101175417
gene id: 8090:LOC101175417
uniprot id: H2M1A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8090:LOC101169622
gene id: 8090:LOC101169622
uniprot id: A0A3B3IH90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

8090:sdf4
gene id: 8090:sdf4
uniprot id: H2MMZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

8090:LOC101154892
gene id: 8090:LOC101154892
uniprot id: H2LQZ9
names: Similarity
messages: Belongs to the PPase family.

8090:LOC101175583
gene id: 8090:LOC101175583
uniprot id: A0A3B3IML7
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8090:LOC101166973
gene id: 8090:LOC101166973
uniprot id: A0A3P9JGC6
uniprot id: H2LIA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

8090:LOC101163114
gene id: 8090:LOC101163114
uniprot id: A0A3P9JNZ4
uniprot id: H2M2A8
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

8090:ccdc124
gene id: 8090:ccdc124
uniprot id: H2LQN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC124 family.
messages: Midbody

8090:LOC101159441
gene id: 8090:LOC101159441
uniprot id: H2LYE1
names: Subcellular Location Annotation
messages: Cytoplasm

8090:ptk2b
gene id: 8090:ptk2b
uniprot id: H2LYR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

8090:3bhsd
gene id: 8090:3bhsd
uniprot id: B5MF69
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8090:LOC101169716
gene id: 8090:LOC101169716
uniprot id: H2LLC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

8090:fgfr3
gene id: 8090:fgfr3
uniprot id: H2MUP1
uniprot id: H2MUP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:tmc4
gene id: 8090:tmc4
uniprot id: H2M6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8090:LOC101161895
gene id: 8090:LOC101161895
uniprot id: A0A3P9IWP4
uniprot id: A0A3P9IWS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

8090:zbed4
gene id: 8090:zbed4
uniprot id: H2M7T4
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101170163
gene id: 8090:LOC101170163
uniprot id: H2L3S4
names: Similarity
messages: Belongs to the TPPP family.

8090:LOC101164404
gene id: 8090:LOC101164404
uniprot id: H2MDR0
names: Similarity
messages: Belongs to the FAM20 family.

8090:steap2
gene id: 8090:steap2
uniprot id: A0A3B3HBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8090:cbr1
gene id: 8090:cbr1
uniprot id: A8IE78
uniprot id: H2L475
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:ypel5
gene id: 8090:ypel5
uniprot id: A0A3P9I2J9
uniprot id: D2KVX5
names: Similarity
messages: Belongs to the yippee family.

8090:LOC100533499
gene id: 8090:LOC100533499
uniprot id: E3WET7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8090:rln
gene id: 8090:rln
uniprot id: Q0Q7C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8090:LOC101164530
gene id: 8090:LOC101164530
uniprot id: A0A3B3IFE5
uniprot id: A0A3P9J8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8090:tcp1
gene id: 8090:tcp1
uniprot id: A0A3B3HHS7
uniprot id: A0A3P9M8T6
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

8090:LOC101170778
gene id: 8090:LOC101170778
uniprot id: H2MEJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:ncdn
gene id: 8090:ncdn
uniprot id: H2M1C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

8090:LOC101163370
gene id: 8090:LOC101163370
uniprot id: H2MV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:dhdds
gene id: 8090:dhdds
uniprot id: A0A3B3HTL6
names: Similarity
messages: Belongs to the UPP synthase family.

8090:LOC101172867
gene id: 8090:LOC101172867
uniprot id: H2MV81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8090:LOC101173175
gene id: 8090:LOC101173175
uniprot id: A0A3B3HGS2
uniprot id: A0A3P9H771
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

8090:fam133b
gene id: 8090:fam133b
uniprot id: H2LGI4
names: Similarity
messages: Belongs to the FAM133 family.

8090:gnb4
gene id: 8090:gnb4
uniprot id: A0A3B3HC45
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8090:fam234a
gene id: 8090:fam234a
uniprot id: H2LVS4
names: Similarity
messages: Belongs to the FAM234 family.

8090:LOC101157559
gene id: 8090:LOC101157559
uniprot id: A0A3B3I9W8
names: Similarity
messages: Belongs to the peptidase M16 family.

8090:gtf2h3
gene id: 8090:gtf2h3
uniprot id: A0A3B3HBK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

8090:LOC100422797
gene id: 8090:LOC100422797
uniprot id: A0A3P9IH62
uniprot id: Q9W612
names: Similarity
messages: Belongs to the phosducin family.

8090:LOC101159102
gene id: 8090:LOC101159102
uniprot id: A0A3B3I076
uniprot id: A0A3P9L657
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:aes
gene id: 8090:aes
uniprot id: H2MQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

8090:bicc1
gene id: 8090:bicc1
uniprot id: H2LKZ1
names: Similarity
messages: Belongs to the BicC family.

8090:samd8
gene id: 8090:samd8
uniprot id: A0A3B3HUV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

8090:LOC101164047
gene id: 8090:LOC101164047
uniprot id: H2LUF1
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101173495
gene id: 8090:LOC101173495
uniprot id: H2MAB2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8090:psmc2
gene id: 8090:psmc2
uniprot id: A0A3B3HAS6
uniprot id: A0A3P9LKG1
names: Similarity
messages: Belongs to the AAA ATPase family.

8090:tmem106b
gene id: 8090:tmem106b
uniprot id: A0A3P9M563
names: Similarity
messages: Belongs to the TMEM106 family.

8090:glul
gene id: 8090:glul
uniprot id: H2MQ60
names: Similarity
messages: Belongs to the glutamine synthetase family.

8090:mrpl41
gene id: 8090:mrpl41
uniprot id: A0A3P9L614
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

8090:LOC101169797
gene id: 8090:LOC101169797
uniprot id: A0A3B3I4A3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:mmp21
gene id: 8090:mmp21
uniprot id: A0A3B3I6Z3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:fxr1
gene id: 8090:fxr1
uniprot id: H2M8G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule

8090:LOC101161259
gene id: 8090:LOC101161259
uniprot id: H2LTF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8090:LOC101163819
gene id: 8090:LOC101163819
uniprot id: A0A3B3H7N2
uniprot id: A0A3P9KQE2
uniprot id: A0A3P9M647
uniprot id: H2MAT9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

8090:flcn
gene id: 8090:flcn
uniprot id: H2M6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

8090:slc17a6
gene id: 8090:slc17a6
uniprot id: H2LMK5
names: Subcellular Location Annotation
messages: Membrane

8090:atic
gene id: 8090:atic
uniprot id: H2LFL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PurH family.
messages: cytosol

8090:LOC101170088
gene id: 8090:LOC101170088
uniprot id: A0A3B3HGD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC101156866
gene id: 8090:LOC101156866
uniprot id: H2MXN5
names: Similarity
messages: Belongs to the peptidase C2 family.

8090:tspan18
gene id: 8090:tspan18
uniprot id: H2LIV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC101167634
gene id: 8090:LOC101167634
uniprot id: A0A3B3HRZ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101173870
gene id: 8090:LOC101173870
uniprot id: H2MT90
names: Subcellular Location Annotation
messages: Membrane

8090:ol-gb
gene id: 8090:ol-gb
uniprot id: Q8QGW8
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

8090:LOC101157262
gene id: 8090:LOC101157262
uniprot id: H2ML20
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:vegfc
gene id: 8090:vegfc
uniprot id: I7HGK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

8090:LOC101165800
gene id: 8090:LOC101165800
uniprot id: H2MGD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8090:cd248
gene id: 8090:cd248
uniprot id: H2L992
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:kcnj13
gene id: 8090:kcnj13
uniprot id: A0A3P9GWZ7
uniprot id: H2M326
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:tmem244
gene id: 8090:tmem244
uniprot id: A0A3P9HTM1
uniprot id: H2MV31
names: Subcellular Location Annotation
messages: Membrane

8090:ephb3
gene id: 8090:ephb3
uniprot id: A0A3B3H3Y8
uniprot id: A0A3P9HY95
uniprot id: A0A3P9JCY7
names: Subcellular Location Annotation
messages: Membrane

8090:tat
gene id: 8090:tat
uniprot id: H2MKL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

8090:nsun6
gene id: 8090:nsun6
uniprot id: H2M5A7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8090:LOC101166485
gene id: 8090:LOC101166485
uniprot id: H2L9D7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

8090:LOC101156275
gene id: 8090:LOC101156275
uniprot id: H2LGN4
names: Similarity
messages: Belongs to the sulfatase family.

8090:LOC101155658
gene id: 8090:LOC101155658
uniprot id: A0A3B3H9I3
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155227
gene id: 8090:LOC101155227
uniprot id: A0A3P9MDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8090:foxd1
gene id: 8090:foxd1
uniprot id: C1K2Y6
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101157613
gene id: 8090:LOC101157613
uniprot id: H2MLZ4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8090:scn3b
gene id: 8090:scn3b
uniprot id: H2LTM1
uniprot id: H2LTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

8090:lck
gene id: 8090:lck
uniprot id: A0A3P9I1K7
uniprot id: H2MSY2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8090:LOC101174517
gene id: 8090:LOC101174517
uniprot id: H2MGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

8090:lin7b
gene id: 8090:lin7b
uniprot id: A0A3B3HFN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

8090:LOC101165806
gene id: 8090:LOC101165806
uniprot id: H2M0T2
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8090:LOC101174914
gene id: 8090:LOC101174914
uniprot id: A0A3P9KAZ6
uniprot id: H2LVA9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:LOC101175073
gene id: 8090:LOC101175073
uniprot id: H2ML50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8090:gamt
gene id: 8090:gamt
uniprot id: A0A3P9L0J1
uniprot id: H2LW55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.
messages: Monomer.

8090:smad6
gene id: 8090:smad6
uniprot id: H2LR75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8090:LOC101157127
gene id: 8090:LOC101157127
uniprot id: H2L4X9
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

8090:LOC101159128
gene id: 8090:LOC101159128
uniprot id: H2LSC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101157455
gene id: 8090:LOC101157455
uniprot id: A0A3B3HNF5
uniprot id: A0A3P9KL20
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

8090:LOC101170929
gene id: 8090:LOC101170929
uniprot id: A0A3B3HTZ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

8090:LOC101174424
gene id: 8090:LOC101174424
uniprot id: H2LKX0
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

8090:c4h1orf52
gene id: 8090:c4h1orf52
uniprot id: H2M562
names: Similarity
messages: Belongs to the UPF0690 family.

8090:LOC101160765
gene id: 8090:LOC101160765
uniprot id: A0A3B3H7S0
uniprot id: H2LYI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8090:itih2
gene id: 8090:itih2
uniprot id: H2MRT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

8090:LOC101163964
gene id: 8090:LOC101163964
uniprot id: A0A3P9LR66
uniprot id: H2LI22
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101158366
gene id: 8090:LOC101158366
uniprot id: A0A3B3H4P9
uniprot id: A0A3P9M0R8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

8090:adgrl1
gene id: 8090:adgrl1
uniprot id: A0A3B3I0F8
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101163808
gene id: 8090:LOC101163808
uniprot id: H2M5B2
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101162102
gene id: 8090:LOC101162102
uniprot id: A0A3B3H3W6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8090:trappc13
gene id: 8090:trappc13
uniprot id: A0A3B3HYM4
uniprot id: H2LCF0
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

8090:osbpl6
gene id: 8090:osbpl6
uniprot id: A0A3B3I187
names: Similarity
messages: Belongs to the OSBP family.

8090:ric8a
gene id: 8090:ric8a
uniprot id: A0A3B3HTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

8090:LOC100144362
gene id: 8090:LOC100144362
uniprot id: A8MN21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.

8090:zeb1
gene id: 8090:zeb1
uniprot id: H2LHC4
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

8090:LOC101166175
gene id: 8090:LOC101166175
uniprot id: A0A3B3HVA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

8090:LOC101173088
gene id: 8090:LOC101173088
uniprot id: H2LGY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

8090:gdf5
gene id: 8090:gdf5
uniprot id: A0A3B3I498
names: Similarity
messages: Belongs to the TGF-beta family.

8090:mylk
gene id: 8090:mylk
uniprot id: A0A3B3H7B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

8090:incenp
gene id: 8090:incenp
uniprot id: B6ZIW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

8090:laptm4a
gene id: 8090:laptm4a
uniprot id: A0A3P9HLL5
uniprot id: H2MB14
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

8090:supv3l1
gene id: 8090:supv3l1
uniprot id: H2M339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

8090:gjc2
gene id: 8090:gjc2
uniprot id: A0A3B3IHH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:sfxn2
gene id: 8090:sfxn2
uniprot id: A0A3B3H6P6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

8090:LOC100049337
gene id: 8090:LOC100049337
uniprot id: Q9W7D8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

8090:tomm22
gene id: 8090:tomm22
uniprot id: A0A3B3I7U3
uniprot id: A0A3P9KC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

8090:tpd52l1
gene id: 8090:tpd52l1
uniprot id: A0A3B3HLU5
names: Similarity
messages: Belongs to the TPD52 family.

8090:rab27a
gene id: 8090:rab27a
uniprot id: H2LXV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

8090:wnt4
gene id: 8090:wnt4
uniprot id: B9V0E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8090:ttc38
gene id: 8090:ttc38
uniprot id: H2MMZ7
names: Similarity
messages: Belongs to the TTC38 family.

8090:pde6g
gene id: 8090:pde6g
uniprot id: H2MFC3
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8090:LOC101163542
gene id: 8090:LOC101163542
uniprot id: H2MYS3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC101160932
gene id: 8090:LOC101160932
uniprot id: H2LZ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:ndufa7
gene id: 8090:ndufa7
uniprot id: A0A3B3HUI3
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

8090:stx18
gene id: 8090:stx18
uniprot id: H2MQE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

8090:LOC101166111
gene id: 8090:LOC101166111
uniprot id: H2L2R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

8090:dusp12
gene id: 8090:dusp12
uniprot id: H2MFF1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8090:LOC101173933
gene id: 8090:LOC101173933
uniprot id: H2L3I7
names: Similarity
messages: Belongs to the GPI family.

8090:kif22
gene id: 8090:kif22
uniprot id: A0A3B3HC96
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:hs2st1
gene id: 8090:hs2st1
uniprot id: A0A3B3IGJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101157787
gene id: 8090:LOC101157787
uniprot id: H2LSB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC101165757
gene id: 8090:LOC101165757
uniprot id: H2LMF0
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

8090:soat1
gene id: 8090:soat1
uniprot id: H2MS31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:tcta
gene id: 8090:tcta
uniprot id: A0A3P9JI61
uniprot id: H2LFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: Membrane

8090:emp2
gene id: 8090:emp2
uniprot id: H2MX21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:tekt2
gene id: 8090:tekt2
uniprot id: H2LYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8090:mterf2
gene id: 8090:mterf2
uniprot id: H2MP66
names: Similarity
messages: Belongs to the mTERF family.

8090:tmem192
gene id: 8090:tmem192
uniprot id: H2LUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

8090:ppme1
gene id: 8090:ppme1
uniprot id: A0A3B3II91
uniprot id: A0A3P9IYW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

8090:LOC101158794
gene id: 8090:LOC101158794
uniprot id: A0A3P9JT01
uniprot id: Q3V624
uniprot id: Q3V625
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8090:acbd5
gene id: 8090:acbd5
uniprot id: H2MC37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane

8090:edil3
gene id: 8090:edil3
uniprot id: A0A3B3H5I3
uniprot id: H2M1Y3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:c9h9orf78
gene id: 8090:c9h9orf78
uniprot id: H2M6V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TLS1 family.
messages: Nucleus

8090:LOC101174109
gene id: 8090:LOC101174109
uniprot id: H2MT99
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101167695
gene id: 8090:LOC101167695
uniprot id: A0A3B3HA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:pygb
gene id: 8090:pygb
uniprot id: H2LCC8
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

8090:LOC101168428
gene id: 8090:LOC101168428
uniprot id: A0A3P9HMI5
uniprot id: B6F103
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101167601
gene id: 8090:LOC101167601
uniprot id: H2N0L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:arrdc2
gene id: 8090:arrdc2
uniprot id: A0A3P9HNA8
uniprot id: H2LXA6
names: Similarity
messages: Belongs to the arrestin family.

8090:taf10
gene id: 8090:taf10
uniprot id: A0A3B3IPB7
uniprot id: A0A3P9MEF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

8090:tmem245
gene id: 8090:tmem245
uniprot id: A0A3B3H3L7
uniprot id: H2LXR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

8090:LOC101157459
gene id: 8090:LOC101157459
uniprot id: H2LD04
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8090:LOC101168217
gene id: 8090:LOC101168217
uniprot id: A0A3B3HA81
names: Similarity
messages: Belongs to the TTC39 family.

8090:vim
gene id: 8090:vim
uniprot id: A0A3B3HL73
names: Similarity
messages: Belongs to the intermediate filament family.

8090:v1ar2
gene id: 8090:v1ar2
uniprot id: H1ADE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:b9d1
gene id: 8090:b9d1
uniprot id: A0A3B3HHP0
names: Subcellular Location Annotation
messages: cilium basal body

8090:LOC101159686
gene id: 8090:LOC101159686
uniprot id: A0A3B3HET2
names: Similarity
messages: Belongs to the RUTBC family.

8090:bet1l
gene id: 8090:bet1l
uniprot id: A0A3P9JU76
names: Subcellular Location Annotation
messages: Membrane

8090:nop56
gene id: 8090:nop56
uniprot id: H2LY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

8090:ptx3
gene id: 8090:ptx3
uniprot id: A0A3B3HFD9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:lsm3
gene id: 8090:lsm3
uniprot id: A0A3B3IFI9
uniprot id: A0A3P9KCL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

8090:LOC101173969
gene id: 8090:LOC101173969
uniprot id: A0A3P9HQM0
uniprot id: H2MAD5
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:LOC101156384
gene id: 8090:LOC101156384
uniprot id: H2L9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

8090:tada1
gene id: 8090:tada1
uniprot id: H2M2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

8090:krr1
gene id: 8090:krr1
uniprot id: H2MZB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

8090:mmgt1
gene id: 8090:mmgt1
uniprot id: A0A3B3HL28
uniprot id: A0A3P9HYT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

8090:pdgfrb
gene id: 8090:pdgfrb
uniprot id: H2LJ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:cyp3a40
gene id: 8090:cyp3a40
uniprot id: Q98T91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

8090:ddx28
gene id: 8090:ddx28
uniprot id: H2M912
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8090:LOC100125509
gene id: 8090:LOC100125509
uniprot id: A0A3P9GZ43
uniprot id: A5HNC4
uniprot id: H2M7I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8090:haus1
gene id: 8090:haus1
uniprot id: H2LHJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

8090:sgo1
gene id: 8090:sgo1
uniprot id: B6F104
uniprot id: H2M9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

8090:LOC101162943
gene id: 8090:LOC101162943
uniprot id: A0A3B3ID53
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

8090:pafah1b1
gene id: 8090:pafah1b1
uniprot id: A0A3P9H272
uniprot id: H2LUZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Component of the cytosolic PAF-AH (I) heterotetrameric enzyme, which is composed of PAFAH1B1 (beta), PAFAH1B2 (alpha2) and PAFAH1B3 (alpha1) subunits. The catalytic activity of the enzyme resides in the alpha1 (PAFAH1B3) and alpha2 (PAFAH1B2) subunits, whereas the beta subunit (PAFAH1B1) has regulatory activity. Trimer formation is not essential for the catalytic activity (By similarity). Interacts with dynein, dynactin, nde1 and ndel1.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

8090:wap65-like
gene id: 8090:wap65-like
uniprot id: Q8JIP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

8090:LOC101169845
gene id: 8090:LOC101169845
uniprot id: H2M6T0
names: Similarity
messages: Belongs to the PWWP3A family.

8090:LOC101158284
gene id: 8090:LOC101158284
uniprot id: H2LV13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8090:nox1
gene id: 8090:nox1
uniprot id: H2L7D0
names: Subcellular Location Annotation
messages: Membrane

8090:rpl24
gene id: 8090:rpl24
uniprot id: A0A3P9M2N3
uniprot id: H2MBQ4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

8090:kfh-g
gene id: 8090:kfh-g
uniprot id: P87366
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
messages: The color pigments are found in the cone photoreceptor cells.
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8090:sprn
gene id: 8090:sprn
uniprot id: A2BDJ8
names: Similarity
messages: Belongs to the SPRN family.

8090:LOC101171566
gene id: 8090:LOC101171566
uniprot id: A0A3B3H4C1
names: Similarity
messages: Belongs to the multicopper oxidase family.

8090:fam214a
gene id: 8090:fam214a
uniprot id: A0A3B3I2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

8090:slc17a9
gene id: 8090:slc17a9
uniprot id: H2M1H1
names: Subcellular Location Annotation
messages: Membrane

8090:fam206a
gene id: 8090:fam206a
uniprot id: A0A3P9JYE6
uniprot id: H2LED5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

8090:ube2g1
gene id: 8090:ube2g1
uniprot id: A0A3B3H5J0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:LOC101170946
gene id: 8090:LOC101170946
uniprot id: H2M669
names: Subcellular Location Annotation
messages: Cytoplasm

8090:cpn1
gene id: 8090:cpn1
uniprot id: H2LIU9
names: Similarity
messages: Belongs to the peptidase M14 family.

8090:LOC101159432
gene id: 8090:LOC101159432
uniprot id: A0A3B3IBN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8090:cntfa
gene id: 8090:cntfa
uniprot id: W8VMK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

8090:LOC101154951
gene id: 8090:LOC101154951
uniprot id: H2MKP7
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic diacylglycerol kinase family.
messages: Monomer.

8090:atg4c
gene id: 8090:atg4c
uniprot id: H2M3N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8090:col4a3bp
gene id: 8090:col4a3bp
uniprot id: A0A3B3I7L8
uniprot id: H2LZY0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

8090:LOC101167287
gene id: 8090:LOC101167287
uniprot id: A0A3P9I7V0
uniprot id: H2M383
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8090:llph
gene id: 8090:llph
uniprot id: A0A3B3HD16
uniprot id: A0A3P9J6G0
names: Similarity
messages: Belongs to the learning-associated protein family.

8090:LOC101162552
gene id: 8090:LOC101162552
uniprot id: H2LXQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

8090:aida
gene id: 8090:aida
uniprot id: A0A3B3HNR2
names: Similarity
messages: Belongs to the AIDA family.

8090:il6st
gene id: 8090:il6st
uniprot id: H2MX70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

8090:fabp7
gene id: 8090:fabp7
uniprot id: A0A3P9JD25
uniprot id: Q2PHF0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:LOC101158138
gene id: 8090:LOC101158138
uniprot id: H2MMY1
names: Subcellular Location Annotation
messages: P-body

8090:ngly1
gene id: 8090:ngly1
uniprot id: H2LXI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Cytoplasm
messages: Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.

8090:hsc70
gene id: 8090:hsc70
uniprot id: Q9W6Y1
names: Domain
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release.
messages: The N-terminal nucleotide binding domain (NBD) (also known as the ATPase domain) is responsible for binding and hydrolyzing ATP. The C-terminal substrate-binding domain (SBD) (also known as peptide-binding domain) binds to the client/substrate proteins. The two domains are allosterically coupled so that, when ATP is bound to the NBD, the SBD binds relatively weakly to clients. When ADP is bound in the NBD, a conformational change enhances the affinity of the SBD for client proteins.

8090:cacnb4.1
gene id: 8090:cacnb4.1
uniprot id: B6IDF8
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

8090:LOC101165751
gene id: 8090:LOC101165751
uniprot id: H2MIS5
names: Similarity
messages: Belongs to the peptidase C19 family.

8090:LOC101172512
gene id: 8090:LOC101172512
uniprot id: H2LVC3
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

8090:LOC101170588
gene id: 8090:LOC101170588
uniprot id: A0A3B3I009
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.

8090:LOC101159096
gene id: 8090:LOC101159096
uniprot id: H2MRI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

8090:LOC101154857
gene id: 8090:LOC101154857
uniprot id: H2MI69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space
messages: Required for assembly of mitochondrial respiratory chain complexes.

8090:lgals3bp
gene id: 8090:lgals3bp
uniprot id: A0A3B3HUF0
names: Subcellular Location Annotation
messages: extracellular matrix

8090:LOC101160370
gene id: 8090:LOC101160370
uniprot id: A0A3P9L9I4
uniprot id: H2MT10
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101157554
gene id: 8090:LOC101157554
uniprot id: H2MDD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

8090:LOC101175179
gene id: 8090:LOC101175179
uniprot id: A0A3B3IP91
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

8090:rpl7a
gene id: 8090:rpl7a
uniprot id: A0A3B3IPI1
uniprot id: A0A3P9KJD4
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

8090:cdk19
gene id: 8090:cdk19
uniprot id: A0A3P9KHD1
uniprot id: H2MK94
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:LOC101175694
gene id: 8090:LOC101175694
uniprot id: H2MVM4
names: Similarity
messages: Belongs to the BZW family.

8090:LOC101165589
gene id: 8090:LOC101165589
uniprot id: J3A6D1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101166386
gene id: 8090:LOC101166386
uniprot id: H2LSI9
names: Similarity
messages: Belongs to the fructosamine kinase family.

8090:tspan33
gene id: 8090:tspan33
uniprot id: A0A3B3HKK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:pglyrp2
gene id: 8090:pglyrp2
uniprot id: A0A3B3HPQ7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

8090:dlx2
gene id: 8090:dlx2
uniprot id: Q0PJT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8090:nkx2-3
gene id: 8090:nkx2-3
uniprot id: H2LU93
names: Subcellular Location Annotation
messages: Nucleus

8090:fam20b
gene id: 8090:fam20b
uniprot id: H2MHX6
names: Similarity
messages: Belongs to the FAM20 family.

8090:LOC100049240
gene id: 8090:LOC100049240
uniprot id: H2LZ89
names: Similarity
messages: Belongs to the peptidase S8 family.

8090:ppp1r10
gene id: 8090:ppp1r10
uniprot id: A0A3B3HU78
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.

8090:LOC101166803
gene id: 8090:LOC101166803
uniprot id: H2ML07
names: Similarity
messages: Belongs to the intermediate filament family.

8090:st6galnac3
gene id: 8090:st6galnac3
uniprot id: Q5K025
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:cryba2
gene id: 8090:cryba2
uniprot id: A0A3P9LYM2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC101156191
gene id: 8090:LOC101156191
uniprot id: A0A3B3I9Z8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8090:LOC101173865
gene id: 8090:LOC101173865
uniprot id: H2MI83
names: Similarity
messages: Belongs to the uridine kinase family.

8090:ubl4a
gene id: 8090:ubl4a
uniprot id: A0A3P9KCL2
uniprot id: H2M600
names: Subcellular Location Annotation
messages: cytosol

8090:ube2c
gene id: 8090:ube2c
uniprot id: A0A3B3I3M6
uniprot id: A0A3P9H4Q5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:hpdl
gene id: 8090:hpdl
uniprot id: H2M161
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

8090:LOC101174227
gene id: 8090:LOC101174227
uniprot id: A0A3B3HWH3
names: Similarity
messages: Belongs to the ependymin family.

8090:LOC101175018
gene id: 8090:LOC101175018
uniprot id: H2L6Z2
names: Subcellular Location Annotation
messages: Membrane

8090:rnf111
gene id: 8090:rnf111
uniprot id: A0A3B3I2L5
uniprot id: H2LVS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arkadia family.
messages: PML body

8090:LOC101171270
gene id: 8090:LOC101171270
uniprot id: H2LI32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8090:gmnn
gene id: 8090:gmnn
uniprot id: Q709D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

8090:LOC101159197
gene id: 8090:LOC101159197
uniprot id: H2MNR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8090:stra6
gene id: 8090:stra6
uniprot id: H2LSK2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101158490
gene id: 8090:LOC101158490
uniprot id: A0A3B3IJP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8090:LOC101169201
gene id: 8090:LOC101169201
uniprot id: H2LC84
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:ucn3
gene id: 8090:ucn3
uniprot id: B1Q2K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

8090:LOC101161409
gene id: 8090:LOC101161409
uniprot id: H2LF27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

8090:adgrl4
gene id: 8090:adgrl4
uniprot id: H2LQ12
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:lonp2
gene id: 8090:lonp2
uniprot id: H2MEF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Peroxisome matrix

8090:LOC101160171
gene id: 8090:LOC101160171
uniprot id: A0A3B3HIP8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8090:LOC101157263
gene id: 8090:LOC101157263
uniprot id: H2MV83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.

8090:LOC101161338
gene id: 8090:LOC101161338
uniprot id: A0A3B3HIE7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:dmap1
gene id: 8090:dmap1
uniprot id: H2LLB7
names: Subcellular Location Annotation
messages: Nucleus

8090:fzd3
gene id: 8090:fzd3
uniprot id: H2MMR4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:hoxa9b
gene id: 8090:hoxa9b
uniprot id: Q9PVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8090:LOC101168403
gene id: 8090:LOC101168403
uniprot id: H2MM65
names: Similarity
messages: Belongs to the mTERF family.

8090:LOC101168162
gene id: 8090:LOC101168162
uniprot id: A0A3B3I807
uniprot id: A0A3P9KTD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8090:LOC101166298
gene id: 8090:LOC101166298
uniprot id: H2MLG3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

8090:manbal
gene id: 8090:manbal
uniprot id: A0A3B3HUQ6
uniprot id: A0A3P9KXE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

8090:fez2
gene id: 8090:fez2
uniprot id: A0A3B3I4F4
uniprot id: A0A3B3IPG0
uniprot id: H2MQN8
names: Similarity
messages: Belongs to the zygin family.

8090:casd1
gene id: 8090:casd1
uniprot id: H2LHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

8090:gpn2
gene id: 8090:gpn2
uniprot id: H2LHU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

8090:srpra
gene id: 8090:srpra
uniprot id: A0A3B3INP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101165301
gene id: 8090:LOC101165301
uniprot id: A0A3B3IGE3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8090:LOC101161366
gene id: 8090:LOC101161366
uniprot id: A0A3B3HQK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8090:cryl1
gene id: 8090:cryl1
uniprot id: H2MCS4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

8090:LOC101167426
gene id: 8090:LOC101167426
uniprot id: A0A3B3H8R8
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

8090:cnot10
gene id: 8090:cnot10
uniprot id: A0A3B3HXE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

8090:LOC101161315
gene id: 8090:LOC101161315
uniprot id: A0A3B3HZ48
uniprot id: A0A3P9LFP1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:LOC101169403
gene id: 8090:LOC101169403
uniprot id: H2MPU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8090:LOC101167907
gene id: 8090:LOC101167907
uniprot id: H2M181
uniprot id: H2M184
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

8090:fam98b
gene id: 8090:fam98b
uniprot id: H2MCJ4
names: Similarity
messages: Belongs to the FAM98 family.

8090:rnf10
gene id: 8090:rnf10
uniprot id: H2MIQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

8090:appl2
gene id: 8090:appl2
uniprot id: H2LCH4
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

8090:LOC101174682
gene id: 8090:LOC101174682
uniprot id: H2M0Y9
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

8090:LOC101167208
gene id: 8090:LOC101167208
uniprot id: H2MES0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8090:csgalnact1
gene id: 8090:csgalnact1
uniprot id: A0A3B3IBN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

8090:LOC101158301
gene id: 8090:LOC101158301
uniprot id: Q3V623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8090:LOC101171810
gene id: 8090:LOC101171810
uniprot id: H2LIN6
names: Subcellular Location Annotation
messages: cytoskeleton

8090:cers1
gene id: 8090:cers1
uniprot id: H2MST5
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101161059
gene id: 8090:LOC101161059
uniprot id: H2LEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8090:tppp
gene id: 8090:tppp
uniprot id: A0A3B3HZC1
names: Similarity
messages: Belongs to the TPPP family.

8090:stk39
gene id: 8090:stk39
uniprot id: A0A3B3HB20
uniprot id: A0A3P9LKS3
uniprot id: H2MRD1
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8090:LOC101160884
gene id: 8090:LOC101160884
uniprot id: A0A3B3I9A6
uniprot id: A0A3P9LLS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:grin2a
gene id: 8090:grin2a
uniprot id: H2MBK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

8090:armt1
gene id: 8090:armt1
uniprot id: A0A3B3I6Y8
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

8090:LOC101172809
gene id: 8090:LOC101172809
uniprot id: A0A3B3HCI8
uniprot id: H2MBU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

8090:ggt1b
gene id: 8090:ggt1b
uniprot id: F1C7I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8090:gosr1
gene id: 8090:gosr1
uniprot id: A0A3P9LG77
uniprot id: H2LW10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

8090:mb
gene id: 8090:mb
uniprot id: A0A3B3H9I9
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

8090:lipt1
gene id: 8090:lipt1
uniprot id: H2L7T5
names: Similarity
messages: Belongs to the LplA family.

8090:thbs2
gene id: 8090:thbs2
uniprot id: H2M4T0
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:dnaaf2
gene id: 8090:dnaaf2
uniprot id: B6F1W5
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIH1 family. Kintoun subfamily.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Organ laterality defects due to altered ciliary motility. Typical randomized left-right mutant leading to situs inversus. Fishes lack directional liquid flow in Kupffer's vesicle (an organ functionally equivalent to the mouse node in terms of left-right specification). Although the number and length of cilia in Kupffer's vesicle seem normal, their motility is completely lost. Homozygous fish are viable but develop primary ciliary dyskinesia. Furthermore, male mutant fish have impaired sperm motility leading to reduced fertility. Ultrastructurally, affected cilia and flagella show partial or complete loss of outer and inner dynein arms. This loss of dynein arms is more severe in Kupffer's vesicle cilia than in sperm flagella.
messages: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.

8090:ppic
gene id: 8090:ppic
uniprot id: A0A3P9MDW7
uniprot id: H2MRL3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8090:LOC101163721
gene id: 8090:LOC101163721
uniprot id: H2MZU8
names: Similarity
messages: Belongs to the peptidase M14 family.

8090:LOC101163344
gene id: 8090:LOC101163344
uniprot id: A0A3B3I623
names: Subcellular Location Annotation
messages: Cell membrane

8090:LOC101156398
gene id: 8090:LOC101156398
uniprot id: H2LSA8
names: Subcellular Location Annotation
messages: Membrane

8090:gpsm1
gene id: 8090:gpsm1
uniprot id: A0A3B3I2J3
uniprot id: H2LQP8
names: Similarity
messages: Belongs to the GPSM family.

8090:LOC101156966
gene id: 8090:LOC101156966
uniprot id: A0A3B3I093
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8090:LOC101174955
gene id: 8090:LOC101174955
uniprot id: A0A3B3IJL4
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

8090:nmnat3
gene id: 8090:nmnat3
uniprot id: H2MG24
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

8090:fut7a
gene id: 8090:fut7a
uniprot id: H2M3X1
uniprot id: Q5F2P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8090:panx2
gene id: 8090:panx2
uniprot id: H2MNY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8090:tbx5
gene id: 8090:tbx5
uniprot id: D1MVS7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8090:LOC101157639
gene id: 8090:LOC101157639
uniprot id: H2LJQ1
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101161904
gene id: 8090:LOC101161904
uniprot id: A0A3B3HK46
uniprot id: A0A3P9LU81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

8090:taldo1
gene id: 8090:taldo1
uniprot id: A0A3P9H0D3
uniprot id: H2L7G1
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

8090:tmem106a
gene id: 8090:tmem106a
uniprot id: H2MX97
names: Similarity
messages: Belongs to the TMEM106 family.

8090:rho
gene id: 8090:rho
uniprot id: P87369
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane
messages: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
messages: Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (PubMed:18422881). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
messages: photoreceptor outer segment

8090:LOC101167828
gene id: 8090:LOC101167828
uniprot id: H2LYV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8090:pltp
gene id: 8090:pltp
uniprot id: H2MD08
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

8090:LOC101161653
gene id: 8090:LOC101161653
uniprot id: Q3V629
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8090:c13h19orf54
gene id: 8090:c13h19orf54
uniprot id: H2LQ33
names: Similarity
messages: Belongs to the ACTMAP family.

8090:LOC101162676
gene id: 8090:LOC101162676
uniprot id: H2MND0
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101161900
gene id: 8090:LOC101161900
uniprot id: A0A3B3HNL0
names: Similarity
messages: Belongs to the SH3RF family.

8090:LOC101163807
gene id: 8090:LOC101163807
uniprot id: H2LBU4
names: Similarity
messages: Belongs to the TEX28 family.

8090:tamm41
gene id: 8090:tamm41
uniprot id: H2LI02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

8090:LOC101163206
gene id: 8090:LOC101163206
uniprot id: H2LBD6
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8090:LOC101158176
gene id: 8090:LOC101158176
uniprot id: H2MWR8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:LOC101160093
gene id: 8090:LOC101160093
uniprot id: H2MDP9
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101163216
gene id: 8090:LOC101163216
uniprot id: H2MPD7
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

8090:LOC100301608
gene id: 8090:LOC100301608
uniprot id: C1K2Y8
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101165795
gene id: 8090:LOC101165795
uniprot id: A0A3P9JUP9
uniprot id: A0A3P9K661
uniprot id: H2LFW0
uniprot id: H2LFW3
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101156608
gene id: 8090:LOC101156608
uniprot id: A0A3B3HDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:rps10
gene id: 8090:rps10
uniprot id: A0A3P9KTK9
uniprot id: H2LSN9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

8090:tmem9b
gene id: 8090:tmem9b
uniprot id: A0A3P9KQ73
uniprot id: H2LRM4
names: Similarity
messages: Belongs to the TMEM9 family.

8090:lgmn
gene id: 8090:lgmn
uniprot id: H2M0N0
names: Similarity
messages: Belongs to the peptidase C13 family.

8090:LOC101156100
gene id: 8090:LOC101156100
uniprot id: A0A3B3HQ86
uniprot id: A0A3P9LQ93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

8090:LOC101173745
gene id: 8090:LOC101173745
uniprot id: H2LHM2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

8090:zfhx4
gene id: 8090:zfhx4
uniprot id: H2LRK5
names: Subcellular Location Annotation
messages: Nucleus

8090:cpvl
gene id: 8090:cpvl
uniprot id: H2LTG9
names: Similarity
messages: Belongs to the peptidase S10 family.

8090:polb
gene id: 8090:polb
uniprot id: A0A3P9LUQ6
uniprot id: H2LB48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

8090:LOC100529177
gene id: 8090:LOC100529177
uniprot id: D2XEB2
names: Function
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein (By similarity). The carboxylated form binds strongly to apatite and calcium.

8090:cers5
gene id: 8090:cers5
uniprot id: A0A3B3H7C5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

8090:wt1
gene id: 8090:wt1
uniprot id: A0A3P9MJ23
uniprot id: A0A3P9MJE7
uniprot id: A5X6J7
uniprot id: H2MAJ6
uniprot id: Q8JIR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

8090:LOC101163890
gene id: 8090:LOC101163890
uniprot id: H2M2B3
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101171191
gene id: 8090:LOC101171191
uniprot id: H2LFB1
names: Similarity
messages: Belongs to the dysbindin family.

8090:LOC101167224
gene id: 8090:LOC101167224
uniprot id: A0A3P9HMI5
uniprot id: B6F103
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:ppp4c
gene id: 8090:ppp4c
uniprot id: A0A3P9MGG4
uniprot id: H2MSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8090:hrh1
gene id: 8090:hrh1
uniprot id: H2LIA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

8090:trhr3
gene id: 8090:trhr3
uniprot id: E5RNC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

8090:LOC101156782
gene id: 8090:LOC101156782
uniprot id: H2MV19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:gk5
gene id: 8090:gk5
uniprot id: H2LIR2
names: Similarity
messages: Belongs to the FGGY kinase family.

8090:nanos2
gene id: 8090:nanos2
uniprot id: B6ZIT4
names: Similarity
messages: Belongs to the nanos family.

8090:mrpl20
gene id: 8090:mrpl20
uniprot id: A0A3P9KIH5
uniprot id: H2MVR9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

8090:rpl13a
gene id: 8090:rpl13a
uniprot id: A0A3P9KUK7
uniprot id: H2MI29
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

8090:LOC101162992
gene id: 8090:LOC101162992
uniprot id: A0A3B3HGL3
uniprot id: A0A3P9LR37
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8090:syngr1
gene id: 8090:syngr1
uniprot id: A0A3P9LYZ8
uniprot id: H2M4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

8090:LOC101155940
gene id: 8090:LOC101155940
uniprot id: A0A3B3I511
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:nsmce4a
gene id: 8090:nsmce4a
uniprot id: H2M7S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

8090:LOC101159516
gene id: 8090:LOC101159516
uniprot id: H2M147
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

8090:tas1r2c
gene id: 8090:tas1r2c
uniprot id: Q2MHK3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101156984
gene id: 8090:LOC101156984
uniprot id: A0A3B3I8K5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8090:rida
gene id: 8090:rida
uniprot id: A0A3B3IFE4
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

8090:LOC101171056
gene id: 8090:LOC101171056
uniprot id: H2M606
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

8090:pax1
gene id: 8090:pax1
uniprot id: C6KTG1
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101157534
gene id: 8090:LOC101157534
uniprot id: A0A3B3HTV7
uniprot id: A0A3P9IYM6
names: Subcellular Location Annotation
messages: Membrane

8090:twf1
gene id: 8090:twf1
uniprot id: A0A3P9L8X1
uniprot id: H2LD71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

8090:lpar1
gene id: 8090:lpar1
uniprot id: A0A3P9IN34
uniprot id: W8VY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

8090:ctsa
gene id: 8090:ctsa
uniprot id: H2M033
names: Similarity
messages: Belongs to the peptidase S10 family.

8090:foxn3
gene id: 8090:foxn3
uniprot id: A0A3P9MJ29
uniprot id: H2M4T1
names: Function
names: Subcellular Location Annotation
messages: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).
messages: Nucleus

8090:c6h11orf49
gene id: 8090:c6h11orf49
uniprot id: H2MHH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: cytoskeleton

8090:fshr
gene id: 8090:fshr
uniprot id: D4QE76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

8090:sox2
gene id: 8090:sox2
uniprot id: C3VV07
uniprot id: Q9PT76
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101169354
gene id: 8090:LOC101169354
uniprot id: A0A3P9M5Y3
uniprot id: H2MQM4
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

8090:snrpe
gene id: 8090:snrpe
uniprot id: A0A3B3HBG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

8090:LOC101174276
gene id: 8090:LOC101174276
uniprot id: H2LKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

8090:nudt19
gene id: 8090:nudt19
uniprot id: H2M8D9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

8090:nxph2
gene id: 8090:nxph2
uniprot id: A0A3B3HQG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8090:LOC105355801
gene id: 8090:LOC105355801
uniprot id: A0A3B3HG24
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:capza2
gene id: 8090:capza2
uniprot id: A0A3B3IPC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

8090:LOC101171575
gene id: 8090:LOC101171575
uniprot id: H2MKS8
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8090:gpr68
gene id: 8090:gpr68
uniprot id: A0A3B3H6Q4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:s2012
gene id: 8090:s2012
uniprot id: C6KXM6
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8090:LOC101155293
gene id: 8090:LOC101155293
uniprot id: H2LG68
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101171534
gene id: 8090:LOC101171534
uniprot id: H2LY70
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

8090:LOC101169753
gene id: 8090:LOC101169753
uniprot id: H2MT66
uniprot id: H2MT68
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

8090:ankrd13b
gene id: 8090:ankrd13b
uniprot id: H2MFP3
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

8090:LOC101169670
gene id: 8090:LOC101169670
uniprot id: H2LHY9
names: Subcellular Location Annotation
messages: Membrane

8090:naa25
gene id: 8090:naa25
uniprot id: A0A3B3HMS6
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

8090:LOC101168360
gene id: 8090:LOC101168360
uniprot id: H2MF51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

8090:LOC101161456
gene id: 8090:LOC101161456
uniprot id: A0A3P9L485
uniprot id: Q76N20
names: Similarity
messages: Belongs to the actin family.

8090:isy1
gene id: 8090:isy1
uniprot id: H2MDG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

8090:LOC101165801
gene id: 8090:LOC101165801
uniprot id: A0A3B3HBQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

8090:pros1
gene id: 8090:pros1
uniprot id: H2LJ91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:smad1
gene id: 8090:smad1
uniprot id: A0A3P9L712
uniprot id: H2LT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8090:gabrg2
gene id: 8090:gabrg2
uniprot id: A0A3B3ICG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:taf6
gene id: 8090:taf6
uniprot id: A0A3P9J4F9
uniprot id: H2LUD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8090:LOC101155358
gene id: 8090:LOC101155358
uniprot id: H2MTM2
names: Similarity
messages: Belongs to the Niban family.

8090:grk7
gene id: 8090:grk7
uniprot id: A0A3P9LQ86
uniprot id: O73658
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8090:LOC101174518
gene id: 8090:LOC101174518
uniprot id: H2LCZ9
names: Subcellular Location Annotation
messages: Nucleus

8090:nectin1
gene id: 8090:nectin1
uniprot id: A0A3B3HM51
uniprot id: A0A3B3ICJ1
uniprot id: A0A3B3IH99
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101167346
gene id: 8090:LOC101167346
uniprot id: H2MH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:ssu72
gene id: 8090:ssu72
uniprot id: A0A3B3HUR2
uniprot id: A0A3P9KI15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

8090:tmc6
gene id: 8090:tmc6
uniprot id: H2M9Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8090:sec22c
gene id: 8090:sec22c
uniprot id: H2M021
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

8090:vps4a
gene id: 8090:vps4a
uniprot id: H2MK58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

8090:atp6v1f
gene id: 8090:atp6v1f
uniprot id: A0A3P9H208
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

8090:slc19a2
gene id: 8090:slc19a2
uniprot id: A0A3B3IJ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

8090:cpsf7
gene id: 8090:cpsf7
uniprot id: H2LQ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

8090:dpep1
gene id: 8090:dpep1
uniprot id: H2LMG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

8090:LOC101174260
gene id: 8090:LOC101174260
uniprot id: A0A3B3IEY7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

8090:LOC100049190
gene id: 8090:LOC100049190
uniprot id: H2MMK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8090:fam136a
gene id: 8090:fam136a
uniprot id: H2M0C3
names: Similarity
messages: Belongs to the FAM136 family.

8090:LOC101158766
gene id: 8090:LOC101158766
uniprot id: H2MM20
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:nlgn1
gene id: 8090:nlgn1
uniprot id: D2X2I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

8090:polr3h
gene id: 8090:polr3h
uniprot id: H2MGM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

8090:mettl8
gene id: 8090:mettl8
uniprot id: H2MS98
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

8090:LOC101172901
gene id: 8090:LOC101172901
uniprot id: H2M7E4
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

8090:ppp1r7
gene id: 8090:ppp1r7
uniprot id: H2MPH2
names: Similarity
messages: Belongs to the SDS22 family.

8090:fut9c
gene id: 8090:fut9c
uniprot id: Q5F2N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8090:avpr2
gene id: 8090:avpr2
uniprot id: D4QF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:anxa11
gene id: 8090:anxa11
uniprot id: O93447
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

8090:tpm4
gene id: 8090:tpm4
uniprot id: A0A3P9KZ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8090:LOC101167899
gene id: 8090:LOC101167899
uniprot id: A0A3B3HGK2
uniprot id: A0A3B3I8Y2
uniprot id: A0A3B3IMT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:LOC101172185
gene id: 8090:LOC101172185
uniprot id: H2MHQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

8090:letm2
gene id: 8090:letm2
uniprot id: A0A3B3HBX9
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

8090:rps4x
gene id: 8090:rps4x
uniprot id: A0A3P9IGN1
uniprot id: H2M0T8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

8090:spsb3
gene id: 8090:spsb3
uniprot id: H2LSM3
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

8090:tm9sf1
gene id: 8090:tm9sf1
uniprot id: H2LPN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

8090:wasf1
gene id: 8090:wasf1
uniprot id: A0A3B3I4V4
uniprot id: H2MG14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8090:dpm3
gene id: 8090:dpm3
uniprot id: H2L4B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

8090:LOC101174905
gene id: 8090:LOC101174905
uniprot id: A0A3B3I6Y3
uniprot id: A0A3P9ISB4
uniprot id: H2L732
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8090:LOC101173940
gene id: 8090:LOC101173940
uniprot id: H2MK56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

8090:fam219b
gene id: 8090:fam219b
uniprot id: A0A3B3HTB2
names: Similarity
messages: Belongs to the FAM219 family.

8090:edn1
gene id: 8090:edn1
uniprot id: H2LZR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8090:aacs
gene id: 8090:aacs
uniprot id: A0A3B3HYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

8090:ercc3
gene id: 8090:ercc3
uniprot id: H2LHP6
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

8090:prps1
gene id: 8090:prps1
uniprot id: A0A3P9M280
uniprot id: H2LP36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

8090:LOC101157969
gene id: 8090:LOC101157969
uniprot id: A0A3P9J5D4
uniprot id: H2MCJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8090:slc7a7
gene id: 8090:slc7a7
uniprot id: A0A3P9H9H1
uniprot id: H2LSN2
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155862
gene id: 8090:LOC101155862
uniprot id: H2LW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

8090:LOC101156654
gene id: 8090:LOC101156654
uniprot id: H2LWY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:LOC101156678
gene id: 8090:LOC101156678
uniprot id: A0A3P9IA86
uniprot id: H2MPC1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:atp5pf
gene id: 8090:atp5pf
uniprot id: A0A3B3H374
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

8090:celf4
gene id: 8090:celf4
uniprot id: A0A3P9H6D5
uniprot id: H2LYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

8090:LOC101167380
gene id: 8090:LOC101167380
uniprot id: H2MCA4
names: Subcellular Location Annotation
messages: Membrane

8090:maml2
gene id: 8090:maml2
uniprot id: A0A3B3HSZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

8090:fibin
gene id: 8090:fibin
uniprot id: A0A3P9ISW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted

8090:LOC100820718
gene id: 8090:LOC100820718
uniprot id: A0A3B3IJS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

8090:lamtor2
gene id: 8090:lamtor2
uniprot id: A0A3P9M9L8
uniprot id: H2MN91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

8090:desi2
gene id: 8090:desi2
uniprot id: A0A3P9JNW5
uniprot id: H2LG38
names: Similarity
messages: Belongs to the DeSI family.

8090:LOC101171164
gene id: 8090:LOC101171164
uniprot id: A0A3B3IFY6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101160359
gene id: 8090:LOC101160359
uniprot id: A0A3P9HQB5
uniprot id: H2LSD4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:foxh1
gene id: 8090:foxh1
uniprot id: C1K2Z5
names: Subcellular Location Annotation
messages: Nucleus

8090:akap12
gene id: 8090:akap12
uniprot id: A0A3B3HQB0
uniprot id: A0A3B3I1W3
names: Subcellular Location Annotation
messages: Membrane

8090:kcnab1
gene id: 8090:kcnab1
uniprot id: A0A3B3H4U9
uniprot id: A0A3B3H782
uniprot id: A0A3P9IIB2
uniprot id: A0A3P9IIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

8090:LOC101172819
gene id: 8090:LOC101172819
uniprot id: A0A3B3I7D1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8090:LOC101155498
gene id: 8090:LOC101155498
uniprot id: A0A3B3I3K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

8090:cilp2
gene id: 8090:cilp2
uniprot id: H2L507
names: Subcellular Location Annotation
messages: Membrane
messages: extracellular matrix

8090:LOC101163575
gene id: 8090:LOC101163575
uniprot id: A0A3P9KEE3
uniprot id: H2LGT2
uniprot id: H2LGT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8090:mid1ip1
gene id: 8090:mid1ip1
uniprot id: A0A3P9KT98
uniprot id: H2M7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

8090:ca8
gene id: 8090:ca8
uniprot id: A0A3B3HWU3
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

8090:ndfip2
gene id: 8090:ndfip2
uniprot id: H2LIE8
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101167979
gene id: 8090:LOC101167979
uniprot id: A0A3P9L8Q9
uniprot id: H2LB13
names: Similarity
messages: Belongs to the pellino family.

8090:LOC101169805
gene id: 8090:LOC101169805
uniprot id: H2LMG8
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

8090:clcn3
gene id: 8090:clcn3
uniprot id: A0A3B3HS58
uniprot id: A0A3P9ITD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8090:LOC101173811
gene id: 8090:LOC101173811
uniprot id: H2M1B8
names: Similarity
messages: Belongs to the S-100 family.

8090:LOC101162938
gene id: 8090:LOC101162938
uniprot id: H2L7C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

8090:slc35a2
gene id: 8090:slc35a2
uniprot id: A0A3B3HYX5
uniprot id: H2MWQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101165390
gene id: 8090:LOC101165390
uniprot id: H2MP91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8090:nov
gene id: 8090:nov
uniprot id: A0A3B3I6G6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101158310
gene id: 8090:LOC101158310
uniprot id: H2LX01
names: Subcellular Location Annotation
messages: extracellular space

8090:slc39a8
gene id: 8090:slc39a8
uniprot id: H2MVC0
names: Subcellular Location Annotation
messages: Membrane

8090:il15ra
gene id: 8090:il15ra
uniprot id: H2M023
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:gpx8
gene id: 8090:gpx8
uniprot id: A0A3B3HGP4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

8090:LOC101156579
gene id: 8090:LOC101156579
uniprot id: A0A3B3IH73
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:LOC101158955
gene id: 8090:LOC101158955
uniprot id: H2LN54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8090:LOC101167371
gene id: 8090:LOC101167371
uniprot id: A0A3B3HBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:mrap2
gene id: 8090:mrap2
uniprot id: A0A3B3HPR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101156244
gene id: 8090:LOC101156244
uniprot id: H2LZZ4
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

8090:LOC101159691
gene id: 8090:LOC101159691
uniprot id: A0A3P9MF50
uniprot id: H2LC75
names: Similarity
messages: Belongs to the NipSnap family.

8090:pigm
gene id: 8090:pigm
uniprot id: H2LKX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

8090:LOC101174197
gene id: 8090:LOC101174197
uniprot id: H2M9I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

8090:idh3a
gene id: 8090:idh3a
uniprot id: A0A3P9JAG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

8090:dnase2
gene id: 8090:dnase2
uniprot id: H2MNE3
names: Similarity
messages: Belongs to the DNase II family.

8090:LOC101174454
gene id: 8090:LOC101174454
uniprot id: A0A3B3HAN3
uniprot id: A0A3P9LSM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

8090:amd1
gene id: 8090:amd1
uniprot id: A0A3P9M0P6
uniprot id: H2MK46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

8090:LOC101173315
gene id: 8090:LOC101173315
uniprot id: A0A3P9L3C9
uniprot id: H2M7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:avil
gene id: 8090:avil
uniprot id: H2MJ91
names: Similarity
messages: Belongs to the villin/gelsolin family.

8090:nefm
gene id: 8090:nefm
uniprot id: A0A3B3HQZ5
names: Similarity
messages: Belongs to the intermediate filament family.

8090:LOC101159498
gene id: 8090:LOC101159498
uniprot id: A0A3B3IKX0
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

8090:atl1
gene id: 8090:atl1
uniprot id: H2LYY5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

8090:rtcb
gene id: 8090:rtcb
uniprot id: H2N0L9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

8090:LOC101159870
gene id: 8090:LOC101159870
uniprot id: H2MSA4
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155401
gene id: 8090:LOC101155401
uniprot id: H2MXI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

8090:nt5c3a
gene id: 8090:nt5c3a
uniprot id: H2MKS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

8090:znf277
gene id: 8090:znf277
uniprot id: H2L5B7
names: Similarity
messages: Belongs to the ZNF277 family.

8090:LOC101174773
gene id: 8090:LOC101174773
uniprot id: A0A3B3HJ47
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:plppr3
gene id: 8090:plppr3
uniprot id: A0A3B3HX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8090:atp11b
gene id: 8090:atp11b
uniprot id: A0A3B3I5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8090:LOC101163143
gene id: 8090:LOC101163143
uniprot id: A0A3B3IPA3
uniprot id: A0A3P9LY13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8090:mrpl2
gene id: 8090:mrpl2
uniprot id: A0A3P9JU61
uniprot id: A0A3P9KBG8
uniprot id: H2MC57
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

8090:LOC101166017
gene id: 8090:LOC101166017
uniprot id: A0A3B3I3L6
uniprot id: A0A3P9LBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

8090:lyz
gene id: 8090:lyz
uniprot id: C3V6M9
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

8090:cnn2
gene id: 8090:cnn2
uniprot id: H2LLV4
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

8090:slc25a43
gene id: 8090:slc25a43
uniprot id: H2L9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:uxt
gene id: 8090:uxt
uniprot id: A0A3B3HF63
names: Similarity
messages: Belongs to the UXT family.

8090:mapre2
gene id: 8090:mapre2
uniprot id: A0A3B3HYQ7
uniprot id: A0A3B3I4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

8090:LOC101163783
gene id: 8090:LOC101163783
uniprot id: A0A3P9L2J3
uniprot id: H2MUD6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:fbxl5
gene id: 8090:fbxl5
uniprot id: H2MNC6
names: Subcellular Location Annotation
messages: perinuclear region

f-3
gene id: 8090:il-17a/f-3
uniprot id: A0A3P9K718
uniprot id: E3WEA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8090:LOC101172653
gene id: 8090:LOC101172653
uniprot id: A0A3P9JDN9
uniprot id: H2L946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:LOC101161968
gene id: 8090:LOC101161968
uniprot id: H2MK68
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101163075
gene id: 8090:LOC101163075
uniprot id: H2MK87
names: Similarity
messages: Belongs to the centaurin gamma-like family.

8090:LOC101158865
gene id: 8090:LOC101158865
uniprot id: A0A3P9I5U3
uniprot id: H2L9Y3
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

8090:exoc3
gene id: 8090:exoc3
uniprot id: H2LH20
names: Similarity
messages: Belongs to the SEC6 family.

8090:LOC101173079
gene id: 8090:LOC101173079
uniprot id: A0A3B3IJS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

8090:mms19
gene id: 8090:mms19
uniprot id: A0A3B3H9P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

8090:mpv17l2
gene id: 8090:mpv17l2
uniprot id: H2LWJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

8090:LOC101172802
gene id: 8090:LOC101172802
uniprot id: H2M8W5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:LOC101166510
gene id: 8090:LOC101166510
uniprot id: H2M9M5
names: Subcellular Location Annotation
messages: lamellipodium

8090:LOC101175546
gene id: 8090:LOC101175546
uniprot id: H2LKP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

8090:LOC101158391
gene id: 8090:LOC101158391
uniprot id: A0A3B3H7G0
uniprot id: A0A3B3IFR6
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

8090:LOC101159585
gene id: 8090:LOC101159585
uniprot id: A0A3B3IFT2
uniprot id: A0A3P9K5F6
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

8090:dctn6
gene id: 8090:dctn6
uniprot id: A0A3B3IEL4
uniprot id: A0A3P9LYD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
messages: cytoskeleton

8090:p4ha2
gene id: 8090:p4ha2
uniprot id: H2MXU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

8090:LOC101166714
gene id: 8090:LOC101166714
uniprot id: A0A3P9IHM6
uniprot id: H2LTC7
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101169438
gene id: 8090:LOC101169438
uniprot id: H2MMS2
names: Similarity
messages: Belongs to the CYFIP family.

8090:LOC101174681
gene id: 8090:LOC101174681
uniprot id: H2L626
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

8090:LOC101173798
gene id: 8090:LOC101173798
uniprot id: H2LKB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

8090:ucp2
gene id: 8090:ucp2
uniprot id: A0A3B3HM54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:ncl
gene id: 8090:ncl
uniprot id: H2LS06
names: Subcellular Location Annotation
messages: nucleolus

8090:gria2
gene id: 8090:gria2
uniprot id: A0A3P9IFH1
uniprot id: A0A3P9KM07
uniprot id: H2N1C4
uniprot id: H2N1C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8090:timm22
gene id: 8090:timm22
uniprot id: A0A3B3I705
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

8090:LOC101175659
gene id: 8090:LOC101175659
uniprot id: H2MJ94
names: Similarity
messages: Belongs to the AAA ATPase family.

8090:LOC101163490
gene id: 8090:LOC101163490
uniprot id: A0A3P9ICT4
uniprot id: H2M0L9
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101171931
gene id: 8090:LOC101171931
uniprot id: A0A3B3IC44
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8090:LOC101159467
gene id: 8090:LOC101159467
uniprot id: A0A3B3HTU6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

8090:LOC101162427
gene id: 8090:LOC101162427
uniprot id: H2LP86
names: Subcellular Location Annotation
messages: Membrane

8090:tspan12
gene id: 8090:tspan12
uniprot id: A0A3B3IBE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:marveld2
gene id: 8090:marveld2
uniprot id: H2MS83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8090:elovl5
gene id: 8090:elovl5
uniprot id: H2M1E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: dendrite

8090:naaa
gene id: 8090:naaa
uniprot id: H2MBR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid ceramidase family.
messages: Lysosome

8090:slc37a3
gene id: 8090:slc37a3
uniprot id: A0A3P9LMS6
uniprot id: H2M5X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

8090:polr2d
gene id: 8090:polr2d
uniprot id: A0A3P9H402
uniprot id: H2LKT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

8090:nkx3-2
gene id: 8090:nkx3-2
uniprot id: A0A3B3H2Y8
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101165992
gene id: 8090:LOC101165992
uniprot id: A0A3P9K5N0
uniprot id: H2L3Y4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8090:rbp4
gene id: 8090:rbp4
uniprot id: H2LK39
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8090:LOC101173396
gene id: 8090:LOC101173396
uniprot id: A0A3B3I0C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

8090:LOC101163908
gene id: 8090:LOC101163908
uniprot id: H2LLF7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:LOC101171999
gene id: 8090:LOC101171999
uniprot id: H2LQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8090:samhd1
gene id: 8090:samhd1
uniprot id: A0A3B3I2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

8090:LOC101163973
gene id: 8090:LOC101163973
uniprot id: A0A3P9MQ07
uniprot id: H2M548
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:slc6a17
gene id: 8090:slc6a17
uniprot id: H2LNZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:LOC101159438
gene id: 8090:LOC101159438
uniprot id: A0A3B3IDS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8090:tpi1
gene id: 8090:tpi1
uniprot id: H2MB61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

8090:rad1
gene id: 8090:rad1
uniprot id: H2LMW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

8090:jpt1
gene id: 8090:jpt1
uniprot id: A0A3B3IEK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

8090:bmp10
gene id: 8090:bmp10
uniprot id: H2ML74
names: Similarity
messages: Belongs to the TGF-beta family.

8090:ppm1f
gene id: 8090:ppm1f
uniprot id: H2MSA7
names: Similarity
messages: Belongs to the PP2C family.

8090:nipa2
gene id: 8090:nipa2
uniprot id: H2MMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

8090:sox4
gene id: 8090:sox4
uniprot id: C3VV08
names: Subcellular Location Annotation
messages: Nucleus

8090:vmhc
gene id: 8090:vmhc
uniprot id: C6L8J0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8090:poll
gene id: 8090:poll
uniprot id: H2MC49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus

8090:LOC101161984
gene id: 8090:LOC101161984
uniprot id: H2MEX0
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

8090:LOC101167607
gene id: 8090:LOC101167607
uniprot id: H2MBD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:rnps1
gene id: 8090:rnps1
uniprot id: A0A3B3I2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

8090:LOC101164493
gene id: 8090:LOC101164493
uniprot id: H2LE18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

8090:nptx1
gene id: 8090:nptx1
uniprot id: H2L8L3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:meox1
gene id: 8090:meox1
uniprot id: H2M8N6
names: Subcellular Location Annotation
messages: Nucleus

8090:vapa
gene id: 8090:vapa
uniprot id: A0A3B3IE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:gtf2e2
gene id: 8090:gtf2e2
uniprot id: A0A3B3HG25
uniprot id: A0A3P9HBL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

8090:LOC101162901
gene id: 8090:LOC101162901
uniprot id: H2LK78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

8090:LOC101155815
gene id: 8090:LOC101155815
uniprot id: H2LZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

8090:b4galt3
gene id: 8090:b4galt3
uniprot id: H2LXU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8090:baz1b
gene id: 8090:baz1b
uniprot id: H2M7P3
names: Subcellular Location Annotation
messages: Nucleus

8090:timp3
gene id: 8090:timp3
uniprot id: Q4W7T5
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8090:LOC101173852
gene id: 8090:LOC101173852
uniprot id: A0A3B3H6J8
names: Similarity
messages: Belongs to the DNase II family.

8090:cdc45
gene id: 8090:cdc45
uniprot id: H2LBX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

8090:wdr76
gene id: 8090:wdr76
uniprot id: H2MAV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

8090:uchl5
gene id: 8090:uchl5
uniprot id: H2M9Z1
names: Similarity
messages: Belongs to the peptidase C12 family.

8090:cpsf4
gene id: 8090:cpsf4
uniprot id: A0A3B3HXW3
uniprot id: A0A3P9LZT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

8090:sdr42e1
gene id: 8090:sdr42e1
uniprot id: H2MG81
names: Similarity
messages: Belongs to the 3-beta-HSD family.

8090:lcat
gene id: 8090:lcat
uniprot id: H2MAY7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

8090:cryz
gene id: 8090:cryz
uniprot id: H2MDV4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8090:mdm4
gene id: 8090:mdm4
uniprot id: A0A3B3HVM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Nucleus

8090:LOC101159587
gene id: 8090:LOC101159587
uniprot id: A0A3P9H4L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8090:lepa
gene id: 8090:lepa
uniprot id: Q588F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the leptin family.
messages: Expressed at moderate levels in the liver. Expressed at low levels in skin, gill, muscle, intestine and eye tissue.
messages: May function as part of a signaling pathway that acts to regulate the size of the body fat depot.
messages: Secreted

8090:LOC101167459
gene id: 8090:LOC101167459
uniprot id: A0A3P9MPM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

8090:LOC101162714
gene id: 8090:LOC101162714
uniprot id: A0A3B3I1C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:exosc9
gene id: 8090:exosc9
uniprot id: H2L9D9
names: Subcellular Location Annotation
messages: Cytoplasm

8090:cav3
gene id: 8090:cav3
uniprot id: H2L537
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

8090:creg2
gene id: 8090:creg2
uniprot id: H2MA25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

8090:tmprss15
gene id: 8090:tmprss15
uniprot id: A4UWM6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: extracellular space

8090:LOC101162690
gene id: 8090:LOC101162690
uniprot id: H2LDL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:dtnbp1
gene id: 8090:dtnbp1
uniprot id: A0A3B3HWL3
names: Similarity
messages: Belongs to the dysbindin family.

8090:LOC101175205
gene id: 8090:LOC101175205
uniprot id: H2MQU6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

8090:qars
gene id: 8090:qars
uniprot id: H2M4U8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8090:LOC101160249
gene id: 8090:LOC101160249
uniprot id: H2LDC8
names: Subcellular Location Annotation
messages: Membrane

8090:epo
gene id: 8090:epo
uniprot id: A0A2Z5WSJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
messages: Secreted

8090:mpg
gene id: 8090:mpg
uniprot id: H2LKG3
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

8090:LOC101163425
gene id: 8090:LOC101163425
uniprot id: A0A3B3H4V1
uniprot id: A0A3B3I945
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8090:rgn
gene id: 8090:rgn
uniprot id: A0A3B3ILB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

8090:LOC101161892
gene id: 8090:LOC101161892
uniprot id: H2MPH7
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8090:spock1
gene id: 8090:spock1
uniprot id: H2LHF3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:grk1
gene id: 8090:grk1
uniprot id: O73659
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8090:stoml2
gene id: 8090:stoml2
uniprot id: H2MW44
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8090:penk
gene id: 8090:penk
uniprot id: A0A3B3H2Q8
names: Similarity
messages: Belongs to the opioid neuropeptide precursor family.

8090:sox14
gene id: 8090:sox14
uniprot id: A0A3P9H6U6
uniprot id: C3VV16
names: Subcellular Location Annotation
messages: Nucleus

8090:paip2
gene id: 8090:paip2
uniprot id: A0A3B3HK50
names: Similarity
messages: Belongs to the PAIP2 family.

8090:six4
gene id: 8090:six4
uniprot id: H2MLZ5
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101169244
gene id: 8090:LOC101169244
uniprot id: H2LK77
names: Similarity
messages: Belongs to the copine family.

8090:acp5
gene id: 8090:acp5
uniprot id: H2MIA0
names: Cofactor
messages: Binds 2 iron ions per subunit.

8090:sh3yl1
gene id: 8090:sh3yl1
uniprot id: H2L7U7
names: Similarity
messages: Belongs to the SH3YL1 family.

8090:LOC101160003
gene id: 8090:LOC101160003
uniprot id: A0A3B3HEI0
uniprot id: A0A3P9I210
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8090:rpl36
gene id: 8090:rpl36
uniprot id: A0A3P9ITW5
uniprot id: H2LBS7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

8090:pnrc2
gene id: 8090:pnrc2
uniprot id: A0A3P9H521
uniprot id: H2MIQ0
names: Subcellular Location Annotation
messages: Nucleus

8090:met
gene id: 8090:met
uniprot id: H2MZM4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:barx2
gene id: 8090:barx2
uniprot id: H2ME19
names: Subcellular Location Annotation
messages: Nucleus

8090:jpt2
gene id: 8090:jpt2
uniprot id: H2M7W5
uniprot id: I7JI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

8090:hdhd2
gene id: 8090:hdhd2
uniprot id: H2M8S1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8090:str-3
gene id: 8090:str-3
uniprot id: Q8QGW9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:LOC101157017
gene id: 8090:LOC101157017
uniprot id: A0A3B3HIE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

8090:dnph1
gene id: 8090:dnph1
uniprot id: H2LDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus

8090:gtf2f2
gene id: 8090:gtf2f2
uniprot id: H2LHH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

8090:rpa3
gene id: 8090:rpa3
uniprot id: A0A3B3I351
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

8090:LOC101156491
gene id: 8090:LOC101156491
uniprot id: H2M070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

8090:ctnnbl1
gene id: 8090:ctnnbl1
uniprot id: H2L5Q4
names: Subcellular Location Annotation
messages: Nucleus

8090:calcb
gene id: 8090:calcb
uniprot id: A0A3B3HC82
uniprot id: A0A3P9I9M1
uniprot id: A0A3P9LQ57
uniprot id: Q05K84
uniprot id: Q05K86
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

8090:LOC101155634
gene id: 8090:LOC101155634
uniprot id: A0A3B3HNH0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:lrit3
gene id: 8090:lrit3
uniprot id: H2N243
names: Subcellular Location Annotation
messages: Membrane

8090:eml4
gene id: 8090:eml4
uniprot id: H2LEC6
names: Similarity
messages: Belongs to the WD repeat EMAP family.

8090:ubr1
gene id: 8090:ubr1
uniprot id: H2MN21
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

8090:mras
gene id: 8090:mras
uniprot id: H2MV62
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8090:LOC101162031
gene id: 8090:LOC101162031
uniprot id: A0A3B3IIQ4
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101164354
gene id: 8090:LOC101164354
uniprot id: A0A3P9K4I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

8090:hoxd10
gene id: 8090:hoxd10
uniprot id: Q3V5Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

8090:smg6
gene id: 8090:smg6
uniprot id: H2LDV9
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini.
messages: Plays a role in nonsense-mediated mRNA decay.
messages: The PINc domain confers endonuclease activity and is expected to bind the catalytic metal ion.
messages: cytosol
messages: nucleolus
messages: telomere

8090:LOC101160692
gene id: 8090:LOC101160692
uniprot id: A0A3B3I8P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

8090:wfikkn2
gene id: 8090:wfikkn2
uniprot id: H2M4D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Membrane
messages: Secreted

8090:LOC101169122
gene id: 8090:LOC101169122
uniprot id: H2LCX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

8090:lasp1
gene id: 8090:lasp1
uniprot id: A0A3B3HT50
uniprot id: A0A3P9KLB4
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

8090:pla2g15
gene id: 8090:pla2g15
uniprot id: H2MAW1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

8090:LOC101155470
gene id: 8090:LOC101155470
uniprot id: A0A3B3IGC3
names: Similarity
messages: Belongs to the RAMP family.

8090:gck
gene id: 8090:gck
uniprot id: H2L9G4
names: Similarity
messages: Belongs to the hexokinase family.

8090:timm13
gene id: 8090:timm13
uniprot id: A0A3B3HMX7
uniprot id: A0A3P9IG22
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8090:LOC101162105
gene id: 8090:LOC101162105
uniprot id: A0A3B3I7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

8090:tsfm
gene id: 8090:tsfm
uniprot id: A0A3B3HE68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

8090:LOC101170524
gene id: 8090:LOC101170524
uniprot id: A0A3B3HNY1
uniprot id: A0A3P9I6P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

8090:LOC101175199
gene id: 8090:LOC101175199
uniprot id: A0A3B3HAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

8090:pds5b
gene id: 8090:pds5b
uniprot id: A0A3B3HAE0
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101154954
gene id: 8090:LOC101154954
uniprot id: A0A3B3H9X1
uniprot id: A0A3P9H5A6
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8090:LOC101173737
gene id: 8090:LOC101173737
uniprot id: H2LSM2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

8090:LOC101168738
gene id: 8090:LOC101168738
uniprot id: A0A3P9LC08
uniprot id: H2LQI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8090:lhb
gene id: 8090:lhb
uniprot id: A0A3P9II02
uniprot id: A7UDN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of an alpha and a beta chain.
messages: Involved in gametogenesis and steroidogenesis.
messages: Secreted

8090:LOC101169632
gene id: 8090:LOC101169632
uniprot id: A0A3B3HEI4
names: Similarity
messages: Belongs to the PRORSD1 family.

8090:cdip1
gene id: 8090:cdip1
uniprot id: H2LKA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

8090:alv
gene id: 8090:alv
uniprot id: Q9IBE7
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:flnc
gene id: 8090:flnc
uniprot id: G9M9P0
uniprot id: G9M9P1
names: Similarity
messages: Belongs to the filamin family.

8090:LOC101162323
gene id: 8090:LOC101162323
uniprot id: H2M4D5
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

8090:gcnt1
gene id: 8090:gcnt1
uniprot id: H2LME6
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

8090:dgkb
gene id: 8090:dgkb
uniprot id: H2MQ64
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

8090:LOC101172973
gene id: 8090:LOC101172973
uniprot id: A0A3P9J2C2
uniprot id: H2MPS1
names: Similarity
messages: Belongs to the intermediate filament family.

8090:LOC101163602
gene id: 8090:LOC101163602
uniprot id: A0A3P9IGD1
uniprot id: H2LW57
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

8090:LOC101174416
gene id: 8090:LOC101174416
uniprot id: A0A3B3HEC8
uniprot id: A0A3P9GZN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8090:taf6l
gene id: 8090:taf6l
uniprot id: H2M8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

8090:LOC101164588
gene id: 8090:LOC101164588
uniprot id: H2MGD6
names: Subcellular Location Annotation
messages: Membrane

8090:vps37b
gene id: 8090:vps37b
uniprot id: A0A3B3H4J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

8090:LOC105354577
gene id: 8090:LOC105354577
uniprot id: H2M5V6
names: Similarity
messages: Belongs to the IER family.

8090:LOC101159273
gene id: 8090:LOC101159273
uniprot id: A0A3P9H3P0
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8090:nde1
gene id: 8090:nde1
uniprot id: H2MEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8090:szrd1
gene id: 8090:szrd1
uniprot id: A0A3B3IKS0
uniprot id: A0A3P9H9V1
names: Similarity
messages: Belongs to the SZRD1 family.

8090:LOC101160625
gene id: 8090:LOC101160625
uniprot id: A0A3B3I3V0
uniprot id: A0A3B3I6K2
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101159109
gene id: 8090:LOC101159109
uniprot id: A0A3P9MNM3
uniprot id: H2MLR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8090:trim71
gene id: 8090:trim71
uniprot id: A0A3B3I8B0
names: Similarity
messages: Belongs to the TRIM/RBCC family.

8090:mcrip1
gene id: 8090:mcrip1
uniprot id: A0A3P9KRD5
uniprot id: H2MA91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

8090:cdc25b
gene id: 8090:cdc25b
uniprot id: H2MVG1
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

8090:cacng3
gene id: 8090:cacng3
uniprot id: A0A3P9ILF5
uniprot id: H2MBQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8090:LOC101161114
gene id: 8090:LOC101161114
uniprot id: A0A3B3HYU5
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

8090:LOC101157206
gene id: 8090:LOC101157206
uniprot id: A0A3B3H431
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

8090:zic5
gene id: 8090:zic5
uniprot id: H2M663
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8090:LOC101169786
gene id: 8090:LOC101169786
uniprot id: Q3V618
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8090:LOC101158814
gene id: 8090:LOC101158814
uniprot id: H2MLJ9
names: Similarity
messages: Belongs to the YY transcription factor family.

8090:LOC101174730
gene id: 8090:LOC101174730
uniprot id: A0A3B3HXI3
uniprot id: A0A3P9J7D5
names: Similarity
messages: Belongs to the intermediate filament family.

8090:LOC101171824
gene id: 8090:LOC101171824
uniprot id: H2MJQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8090:pld5
gene id: 8090:pld5
uniprot id: H2MCZ4
names: Similarity
messages: Belongs to the phospholipase D family.

8090:LOC101157039
gene id: 8090:LOC101157039
uniprot id: A0A3B3HYZ7
uniprot id: A0A3P9KZ16
names: Similarity
messages: Belongs to the IUNH family.

8090:LOC101166988
gene id: 8090:LOC101166988
uniprot id: H2LR65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

8090:LOC101156188
gene id: 8090:LOC101156188
uniprot id: H2LW80
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

8090:ramp1
gene id: 8090:ramp1
uniprot id: A0A3B3I389
names: Similarity
messages: Belongs to the RAMP family.

8090:LOC101155715
gene id: 8090:LOC101155715
uniprot id: A0A3B3IA30
names: Similarity
messages: Belongs to the FXYD family.

8090:pnpo
gene id: 8090:pnpo
uniprot id: A0A3B3HQA5
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

8090:LOC101173307
gene id: 8090:LOC101173307
uniprot id: H2LUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

8090:lefty1
gene id: 8090:lefty1
uniprot id: A2TJL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

8090:LOC101175409
gene id: 8090:LOC101175409
uniprot id: H2LXG5
names: Similarity
messages: Belongs to the LIX1 family.

8090:LOC101166414
gene id: 8090:LOC101166414
uniprot id: H2M7X2
names: Subcellular Location Annotation
messages: Nucleus

8090:hscb
gene id: 8090:hscb
uniprot id: A0A3B3HNZ8
names: Similarity
messages: Belongs to the HscB family.

8090:LOC101156652
gene id: 8090:LOC101156652
uniprot id: H2LMN2
names: Similarity
messages: Belongs to the DNase I family.

8090:wisp2
gene id: 8090:wisp2
uniprot id: H2MNZ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:sgk3
gene id: 8090:sgk3
uniprot id: H2LWX9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

8090:timp4
gene id: 8090:timp4
uniprot id: A0A3B3IF84
uniprot id: A0A3P9LC29
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8090:zw10
gene id: 8090:zw10
uniprot id: H2MHF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

8090:rrp7a
gene id: 8090:rrp7a
uniprot id: H2MIV6
names: Similarity
messages: Belongs to the RRP7 family.

8090:itpka
gene id: 8090:itpka
uniprot id: H2MKW3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8090:tyr
gene id: 8090:tyr
uniprot id: P55025
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Binds 2 copper ions per subunit.
messages: Melanosome membrane
messages: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds.

8090:il-17n
gene id: 8090:il-17n
uniprot id: E3WEB2
names: Similarity
messages: Belongs to the IL-17 family.

8090:mars
gene id: 8090:mars
uniprot id: H2LLA1
uniprot id: H2LLA3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8090:golga5
gene id: 8090:golga5
uniprot id: H2M167
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

8090:LOC101167818
gene id: 8090:LOC101167818
uniprot id: H2LLY2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:amn
gene id: 8090:amn
uniprot id: H2LTV5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101175393
gene id: 8090:LOC101175393
uniprot id: H2LEJ3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:cdk9
gene id: 8090:cdk9
uniprot id: A0A3P9HYQ6
uniprot id: H2MVN9
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:LOC101157297
gene id: 8090:LOC101157297
uniprot id: H2MIV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:s1pr1
gene id: 8090:s1pr1
uniprot id: A0A3P9LLD4
uniprot id: H2MGD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101156047
gene id: 8090:LOC101156047
uniprot id: A0A3B3I3V1
uniprot id: A0A3P9LSL1
names: Similarity
messages: Belongs to the RAMP family.

8090:tyw3
gene id: 8090:tyw3
uniprot id: H2LHZ4
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

8090:LOC101161683
gene id: 8090:LOC101161683
uniprot id: H2MUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101166288
gene id: 8090:LOC101166288
uniprot id: A0A3P9M9Y5
uniprot id: H2LNX0
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101165333
gene id: 8090:LOC101165333
uniprot id: H2L3U7
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

8090:LOC101171333
gene id: 8090:LOC101171333
uniprot id: A0A3B3HPT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:crcp
gene id: 8090:crcp
uniprot id: A0A3B3HW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

8090:zdhhc3
gene id: 8090:zdhhc3
uniprot id: A0A3B3HDU3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:LOC101164463
gene id: 8090:LOC101164463
uniprot id: H2L7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:fgf18
gene id: 8090:fgf18
uniprot id: A0A3B3I3C9
uniprot id: A0A3P9IK15
uniprot id: A0A3P9MBC1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8090:LOC101172392
gene id: 8090:LOC101172392
uniprot id: A0A3B3I8X1
uniprot id: A0A3P9JZ11
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

8090:nxph4
gene id: 8090:nxph4
uniprot id: A0A3B3HFT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: Secreted

8090:mocos
gene id: 8090:mocos
uniprot id: A0A3B3I9E5
uniprot id: A0A3B3ICT0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

8090:LOC100049432
gene id: 8090:LOC100049432
uniprot id: P79817
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

8090:tmem144
gene id: 8090:tmem144
uniprot id: H2N140
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

8090:sox21
gene id: 8090:sox21
uniprot id: A0A3P9MIP5
uniprot id: C3VV19
names: Subcellular Location Annotation
messages: Nucleus

8090:gpd2
gene id: 8090:gpd2
uniprot id: A0A3B3H9S9
uniprot id: H2L2W0
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

8090:LOC101173215
gene id: 8090:LOC101173215
uniprot id: H2MH99
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101156893
gene id: 8090:LOC101156893
uniprot id: H2LWZ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:sap130
gene id: 8090:sap130
uniprot id: H2ML39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

8090:LOC101157234
gene id: 8090:LOC101157234
uniprot id: A0A3B3HG91
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:LOC101161189
gene id: 8090:LOC101161189
uniprot id: A0A3P9IY25
uniprot id: H2MFX3
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

8090:per1
gene id: 8090:per1
uniprot id: B3Y055
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:polr2f
gene id: 8090:polr2f
uniprot id: H2MI10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus

8090:aptx
gene id: 8090:aptx
uniprot id: H2LP58
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

8090:rexo4
gene id: 8090:rexo4
uniprot id: H2LRH4
names: Similarity
messages: Belongs to the REXO4 family.

8090:snx11
gene id: 8090:snx11
uniprot id: A0A3B3I405
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8090:kdm1a
gene id: 8090:kdm1a
uniprot id: H2MB68
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family.
messages: Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity.
messages: Nucleus
messages: The SWIRM domain may act as an anchor site for a histone tail.

8090:LOC101172536
gene id: 8090:LOC101172536
uniprot id: H2LWN8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:adprh
gene id: 8090:adprh
uniprot id: H2LNN1
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

8090:LOC101171492
gene id: 8090:LOC101171492
uniprot id: A0A3B3HQU4
uniprot id: H2MNI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

8090:vps52
gene id: 8090:vps52
uniprot id: H2L6C1
names: Similarity
messages: Belongs to the VPS52 family.

8090:adamts1
gene id: 8090:adamts1
uniprot id: Q4AED3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8090:alox5
gene id: 8090:alox5
uniprot id: H2LTD7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:pim3
gene id: 8090:pim3
uniprot id: A0A3P9LM81
uniprot id: H2M7J8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8090:LOC101168301
gene id: 8090:LOC101168301
uniprot id: A0A3B3HN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8090:gatad1
gene id: 8090:gatad1
uniprot id: A0A3P9HZF3
names: Subcellular Location Annotation
messages: Nucleus

8090:ino80
gene id: 8090:ino80
uniprot id: H2MUW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

8090:LOC101172993
gene id: 8090:LOC101172993
uniprot id: A0A3B3HET7
uniprot id: H2M448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:cct3
gene id: 8090:cct3
uniprot id: H2L824
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8090:acod1
gene id: 8090:acod1
uniprot id: A0A3B3IGX4
names: Similarity
messages: Belongs to the PrpD family.

8090:wdr35
gene id: 8090:wdr35
uniprot id: A0A3B3IAS5
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

8090:LOC101173155
gene id: 8090:LOC101173155
uniprot id: A0A3B3HD84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

8090:LOC101164789
gene id: 8090:LOC101164789
uniprot id: A0A3B3HPI4
uniprot id: A0A3P9JY86
uniprot id: H2MA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8090:LOC100049233
gene id: 8090:LOC100049233
uniprot id: Q76LM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8090:lgr6
gene id: 8090:lgr6
uniprot id: H2LWV4
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101163044
gene id: 8090:LOC101163044
uniprot id: A0A3B3IHT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:dram1
gene id: 8090:dram1
uniprot id: H2MLN1
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101166137
gene id: 8090:LOC101166137
uniprot id: A0A3P9I8F2
uniprot id: H2L8L6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:fermt3
gene id: 8090:fermt3
uniprot id: H2LB73
names: Similarity
messages: Belongs to the kindlin family.

8090:hdac3
gene id: 8090:hdac3
uniprot id: A0A3B3IBG8
uniprot id: A0A3P9JGE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

8090:b3gat2
gene id: 8090:b3gat2
uniprot id: Q599J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:fam57b
gene id: 8090:fam57b
uniprot id: H2LNZ4
names: Subcellular Location Annotation
messages: Membrane

8090:sephs1
gene id: 8090:sephs1
uniprot id: A0A3P9JY74
uniprot id: H2M352
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

8090:clstn1
gene id: 8090:clstn1
uniprot id: A0A3B3HW45
uniprot id: H2LL31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

8090:b3galt6
gene id: 8090:b3galt6
uniprot id: Q256Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:tdrd3
gene id: 8090:tdrd3
uniprot id: H2LI37
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.

8090:mettl14
gene id: 8090:mettl14
uniprot id: A0A3P9IRB6
uniprot id: H2LNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MT-A70-like family.
messages: Heterodimer; heterodimerizes with mettl3 to form an antiparallel heterodimer that constitutes an active methyltransferase.
messages: Nucleus
messages: The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with mettl3, mettl14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing.

8090:rpl37a
gene id: 8090:rpl37a
uniprot id: A0A3P9KIA6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

8090:dpy19l1
gene id: 8090:dpy19l1
uniprot id: A0A3B3IKM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

8090:LOC101156301
gene id: 8090:LOC101156301
uniprot id: H2L2T9
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

8090:timp-2b
gene id: 8090:timp-2b
uniprot id: A0A3P9J6I3
uniprot id: Q4W7T6
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8090:efnb1
gene id: 8090:efnb1
uniprot id: A0A3B3IL23
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101167721
gene id: 8090:LOC101167721
uniprot id: H2LUA4
names: Similarity
messages: Belongs to the FAM98 family.

8090:foxn4
gene id: 8090:foxn4
uniprot id: H2LTT7
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101159252
gene id: 8090:LOC101159252
uniprot id: H2L351
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8090:dusp10
gene id: 8090:dusp10
uniprot id: A0A3P9MDN5
uniprot id: H2M9A8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8090:anapc4
gene id: 8090:anapc4
uniprot id: H2L3R5
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

8090:ripor2
gene id: 8090:ripor2
uniprot id: A0A3B3HUL0
uniprot id: H2MC60
names: Similarity
messages: Belongs to the RIPOR family.

8090:LOC101157910
gene id: 8090:LOC101157910
uniprot id: A0A3B3IDD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

8090:tomm40
gene id: 8090:tomm40
uniprot id: H2MEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

8090:olgc8
gene id: 8090:olgc8
uniprot id: Q7ZZR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Photoreceptor outer segment membrane

8090:ucn2
gene id: 8090:ucn2
uniprot id: A0A3P9HEA3
uniprot id: B1Q2K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

8090:LOC100125507
gene id: 8090:LOC100125507
uniprot id: A0A3P9MLU8
uniprot id: A5HNC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

8090:katna1
gene id: 8090:katna1
uniprot id: H2MKL1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

8090:alpk3
gene id: 8090:alpk3
uniprot id: H2MAM6
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101175360
gene id: 8090:LOC101175360
uniprot id: A0A3B3I5I2
uniprot id: A0A3P9LHC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:hgh1
gene id: 8090:hgh1
uniprot id: H2MZR5
names: Similarity
messages: Belongs to the HGH1 family.

8090:gab2
gene id: 8090:gab2
uniprot id: H2LBY3
names: Similarity
messages: Belongs to the GAB family.

8090:LOC101168356
gene id: 8090:LOC101168356
uniprot id: A0A3B3I845
names: Similarity
messages: Belongs to the peptidase S10 family.

8090:LOC101163094
gene id: 8090:LOC101163094
uniprot id: H2M1U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

8090:LOC101174726
gene id: 8090:LOC101174726
uniprot id: H2LRL3
names: Similarity
messages: Belongs to the PP2C family.

8090:xylb
gene id: 8090:xylb
uniprot id: A0A3B3HR91
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

8090:cast
gene id: 8090:cast
uniprot id: A0A3B3HSE5
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I27 (calpastatin) family.
messages: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.

8090:slc12a3
gene id: 8090:slc12a3
uniprot id: V5YU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

8090:tdrd7
gene id: 8090:tdrd7
uniprot id: H2LFM0
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101165330
gene id: 8090:LOC101165330
uniprot id: H2LJW5
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

8090:nif3l1
gene id: 8090:nif3l1
uniprot id: H2LP93
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

8090:LOC101163350
gene id: 8090:LOC101163350
uniprot id: H2MFH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

8090:LOC101166735
gene id: 8090:LOC101166735
uniprot id: H2L6A1
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8090:golt1b
gene id: 8090:golt1b
uniprot id: A0A3P9ICV1
uniprot id: A0A3P9JM66
uniprot id: H2MC04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

8090:LOC101156833
gene id: 8090:LOC101156833
uniprot id: A0A3P9LCZ2
uniprot id: H2M7N9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:LOC101165104
gene id: 8090:LOC101165104
uniprot id: H2LKU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

8090:zdhhc1
gene id: 8090:zdhhc1
uniprot id: A0A3B3HCB5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:phb2
gene id: 8090:phb2
uniprot id: H2LC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

8090:btg3
gene id: 8090:btg3
uniprot id: A0A3B3I9G3
names: Similarity
messages: Belongs to the BTG family.

8090:polr2j
gene id: 8090:polr2j
uniprot id: A0A3B3HFW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

8090:cript
gene id: 8090:cript
uniprot id: A0A3B3IE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

8090:oxtr
gene id: 8090:oxtr
uniprot id: A0A3P9IU49
uniprot id: H1ADE9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101157479
gene id: 8090:LOC101157479
uniprot id: H2LRN7
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

8090:LOC101171015
gene id: 8090:LOC101171015
uniprot id: H2LZK8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8090:LOC101174592
gene id: 8090:LOC101174592
uniprot id: H2M7U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:wwox
gene id: 8090:wwox
uniprot id: H2M3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Golgi apparatus
messages: Lysosome
messages: Mitochondrion

8090:rfc2
gene id: 8090:rfc2
uniprot id: H2MX50
names: Similarity
messages: Belongs to the activator 1 small subunits family.

8090:LOC101163237
gene id: 8090:LOC101163237
uniprot id: H2N167
names: Similarity
messages: Belongs to the TGF-beta family.

8090:habp2
gene id: 8090:habp2
uniprot id: H2MD32
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8090:LOC101174054
gene id: 8090:LOC101174054
uniprot id: A0A3B3IH45
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

8090:LOC101156853
gene id: 8090:LOC101156853
uniprot id: Q90XN7
names: Subcellular Location Annotation
messages: Nucleus

8090:ppil1
gene id: 8090:ppil1
uniprot id: A0A3B3I5P2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8090:setdb1
gene id: 8090:setdb1
uniprot id: H2M4D0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8090:LOC101171247
gene id: 8090:LOC101171247
uniprot id: A0A3P9HBK2
uniprot id: H2MJ85
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8090:LOC101166070
gene id: 8090:LOC101166070
uniprot id: A0A3B3HC12
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8090:gdf3
gene id: 8090:gdf3
uniprot id: H2M3E4
names: Similarity
messages: Belongs to the TGF-beta family.

8090:pomgnt1
gene id: 8090:pomgnt1
uniprot id: H2MDL6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

8090:LOC101163948
gene id: 8090:LOC101163948
uniprot id: A0A3B3ILN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:tfdp1
gene id: 8090:tfdp1
uniprot id: A0A3P9HY99
uniprot id: H2MB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

8090:LOC101170687
gene id: 8090:LOC101170687
uniprot id: A0A3B3HRA1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101168392
gene id: 8090:LOC101168392
uniprot id: A0A3B3HD55
names: Similarity
messages: Belongs to the peptidase C64 family.

8090:dok6
gene id: 8090:dok6
uniprot id: H2LUM6
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

8090:ykt6
gene id: 8090:ykt6
uniprot id: A0A3B3HMD3
uniprot id: A0A3P9KCF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

8090:LOC101158810
gene id: 8090:LOC101158810
uniprot id: A0A3P9LZM8
uniprot id: H2MN29
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101162856
gene id: 8090:LOC101162856
uniprot id: A0A3B3HRN4
uniprot id: A0A3P9MFL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

8090:LOC101170077
gene id: 8090:LOC101170077
uniprot id: H2N112
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

8090:vps25
gene id: 8090:vps25
uniprot id: A0A3B3HZI6
names: Similarity
messages: Belongs to the VPS25 family.

8090:LOC101161753
gene id: 8090:LOC101161753
uniprot id: H2MJ73
uniprot id: H2MJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8090:LOC101161430
gene id: 8090:LOC101161430
uniprot id: H2MJK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

8090:rnf114
gene id: 8090:rnf114
uniprot id: H2M0J4
names: Subunit
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.

8090:insm1
gene id: 8090:insm1
uniprot id: A0A3B3IMM3
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101175629
gene id: 8090:LOC101175629
uniprot id: H2MZM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

8090:cdh2
gene id: 8090:cdh2
uniprot id: A0A0C6G5J1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8090:scube3
gene id: 8090:scube3
uniprot id: H2MCW6
uniprot id: H2MCW9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:stt3a
gene id: 8090:stt3a
uniprot id: A0A3B3IFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

8090:pde8b
gene id: 8090:pde8b
uniprot id: H2LAB6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8090:LOC101158604
gene id: 8090:LOC101158604
uniprot id: H2M8Y9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

8090:LOC101164850
gene id: 8090:LOC101164850
uniprot id: H2M8G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101154963
gene id: 8090:LOC101154963
uniprot id: A0A3B3I490
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

8090:myot
gene id: 8090:myot
uniprot id: H2LYN6
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155616
gene id: 8090:LOC101155616
uniprot id: A0A3P9KNL2
uniprot id: H2LRM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

8090:mrpl17
gene id: 8090:mrpl17
uniprot id: A0A3B3I4J5
uniprot id: A0A3P9HBD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

8090:LOC101165802
gene id: 8090:LOC101165802
uniprot id: H2LZX5
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8090:LOC101175004
gene id: 8090:LOC101175004
uniprot id: H2LJ17
names: Similarity
messages: Belongs to the sulfatase family.

8090:ppp1r14b
gene id: 8090:ppp1r14b
uniprot id: A0A3B3HRX7
uniprot id: A0A3P9KT59
names: Similarity
messages: Belongs to the PP1 inhibitor family.

8090:pgap3
gene id: 8090:pgap3
uniprot id: A0A3B3HYG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:slc25a32
gene id: 8090:slc25a32
uniprot id: H2LAJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:LOC101167611
gene id: 8090:LOC101167611
uniprot id: A0A3B3HK56
uniprot id: A0A3P9LMB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

8090:ermp1
gene id: 8090:ermp1
uniprot id: H2LTI1
names: Subcellular Location Annotation
messages: Membrane

8090:nos1
gene id: 8090:nos1
uniprot id: Q75PZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

8090:aspdh
gene id: 8090:aspdh
uniprot id: H2M788
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.

8090:cisd2
gene id: 8090:cisd2
uniprot id: A0A3P9LJ81
uniprot id: H2LNP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

8090:LOC101158177
gene id: 8090:LOC101158177
uniprot id: H2LI53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:cacybp
gene id: 8090:cacybp
uniprot id: H2MNL6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

8090:stat3
gene id: 8090:stat3
uniprot id: A0A3P9JRQ8
uniprot id: H2LGI9
uniprot id: Q6GUE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8090:LOC101171965
gene id: 8090:LOC101171965
uniprot id: H2MWH8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

8090:timm23
gene id: 8090:timm23
uniprot id: A0A3B3HHS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

8090:LOC101175224
gene id: 8090:LOC101175224
uniprot id: H2N0I3
names: Subcellular Location Annotation
messages: Membrane

8090:slc25a53
gene id: 8090:slc25a53
uniprot id: H2LP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:aurkaip1
gene id: 8090:aurkaip1
uniprot id: H2MFX8
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

8090:LOC101163155
gene id: 8090:LOC101163155
uniprot id: H2LQM9
names: Similarity
messages: Belongs to the nucleobindin family.

8090:LOC101172902
gene id: 8090:LOC101172902
uniprot id: H2MI33
names: Subcellular Location Annotation
messages: Membrane

8090:ran
gene id: 8090:ran
uniprot id: A0A3P9JMZ6
uniprot id: H2LEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

8090:LOC101165558
gene id: 8090:LOC101165558
uniprot id: A0A3B3H5C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

8090:LOC101160498
gene id: 8090:LOC101160498
uniprot id: A0A3B3IBU1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:LOC101158034
gene id: 8090:LOC101158034
uniprot id: A0A3B3ICE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:prepl
gene id: 8090:prepl
uniprot id: H2LHX9
names: Similarity
messages: Belongs to the peptidase S9A family.

8090:LOC101169664
gene id: 8090:LOC101169664
uniprot id: A0A3P9M4R2
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8090:LOC101157694
gene id: 8090:LOC101157694
uniprot id: A0A3P9M3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:mea1
gene id: 8090:mea1
uniprot id: H2LDF5
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

8090:nitr14
gene id: 8090:nitr14
uniprot id: B3TZA5
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155834
gene id: 8090:LOC101155834
uniprot id: H2LDK1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8090:LOC101167198
gene id: 8090:LOC101167198
uniprot id: A0A3B3H3L3
uniprot id: A0A3B3H5A1
uniprot id: A0A3B3HIY0
uniprot id: A0A3P9LYJ6
uniprot id: A0A3P9LZ59
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

8090:LOC101163896
gene id: 8090:LOC101163896
uniprot id: A0A3P9KMF8
uniprot id: H2LM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:KEF90 p12
gene id: 8090:KEF90_p12
uniprot id: Q8HLX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8090:LOC101174707
gene id: 8090:LOC101174707
uniprot id: A0A3B3I8I0
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

8090:sostdc1
gene id: 8090:sostdc1
uniprot id: H2MQ99
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101160039
gene id: 8090:LOC101160039
uniprot id: A0A3P9KMZ1
uniprot id: H2LU55
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:gcdh
gene id: 8090:gcdh
uniprot id: H2MPA7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8090:LOC101167781
gene id: 8090:LOC101167781
uniprot id: H2LMT7
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

8090:nkd2
gene id: 8090:nkd2
uniprot id: H2LVG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

8090:LOC101170519
gene id: 8090:LOC101170519
uniprot id: A0A3B3IHE7
names: Subcellular Location Annotation
messages: Nucleus

8090:atp8b1
gene id: 8090:atp8b1
uniprot id: A0A3B3IJB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

8090:LOC101162120
gene id: 8090:LOC101162120
uniprot id: A0A3B3HCD2
names: Similarity
messages: Belongs to the PPP1R15 family.

8090:LOC101164822
gene id: 8090:LOC101164822
uniprot id: H2M0J9
names: Similarity
messages: Belongs to the EVA1 family.

8090:uts2r
gene id: 8090:uts2r
uniprot id: H2N1E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

8090:dusp26
gene id: 8090:dusp26
uniprot id: A0A3B3IGA5
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

8090:mfap1
gene id: 8090:mfap1
uniprot id: A0A3P9LXC1
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

8090:LOC101171363
gene id: 8090:LOC101171363
uniprot id: H2MSG0
names: Subcellular Location Annotation
messages: Membrane

8090:mmp9
gene id: 8090:mmp9
uniprot id: Q9PVM5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

8090:serinc1
gene id: 8090:serinc1
uniprot id: A0A3P9ISX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8090:mboat2
gene id: 8090:mboat2
uniprot id: A0A3B3I1W2
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101173532
gene id: 8090:LOC101173532
uniprot id: A0A3P9MGW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

8090:pym1
gene id: 8090:pym1
uniprot id: A0A3B3HNT0
names: Similarity
names: Subunit
messages: Belongs to the pym family.
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

8090:pofut1
gene id: 8090:pofut1
uniprot id: Q00P47
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

8090:dph5
gene id: 8090:dph5
uniprot id: H2MGF7
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

8090:LOC101160253
gene id: 8090:LOC101160253
uniprot id: H2L5W7
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

8090:zdhhc15
gene id: 8090:zdhhc15
uniprot id: A0A3P9KLK9
uniprot id: H2LNN7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:LOC101166946
gene id: 8090:LOC101166946
uniprot id: H2LNP7
names: Similarity
messages: Belongs to the TMEM178 family.

8090:hebp1
gene id: 8090:hebp1
uniprot id: H2MJ08
names: Similarity
messages: Belongs to the HEBP family.

8090:LOC101156565
gene id: 8090:LOC101156565
uniprot id: A0A3B3H350
uniprot id: A0A3B3HB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

8090:rgs9
gene id: 8090:rgs9
uniprot id: A0A3B3HXP9
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101169467
gene id: 8090:LOC101169467
uniprot id: A0A3B3I091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

8090:chmp1a
gene id: 8090:chmp1a
uniprot id: A0A3P9KUU0
uniprot id: H2MKA7
names: Similarity
messages: Belongs to the SNF7 family.

8090:eloc
gene id: 8090:eloc
uniprot id: A0A3B3HAL1
uniprot id: A0A3P9L4P8
names: Similarity
messages: Belongs to the SKP1 family.

8090:pigp
gene id: 8090:pigp
uniprot id: H2LRF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

8090:LOC101174266
gene id: 8090:LOC101174266
uniprot id: H2LVG2
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101156593
gene id: 8090:LOC101156593
uniprot id: H2LS13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:LOC101169601
gene id: 8090:LOC101169601
uniprot id: A0A3B3I4R5
uniprot id: A0A3P9J0T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The SEC61 channel-forming translocon complex consists of channel-forming core components SEC61A1, SEC61B and SEC61G and different auxiliary components such as SEC62 and SEC63 (By similarity). The SEC61 channel associates with the multi-pass translocon (MPT) complex.

8090:LOC101159706
gene id: 8090:LOC101159706
uniprot id: H2LLK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

8090:pcnx3
gene id: 8090:pcnx3
uniprot id: H2LN14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

8090:siah1
gene id: 8090:siah1
uniprot id: A0A3P9L666
uniprot id: H2MEL0
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

8090:LOC101163204
gene id: 8090:LOC101163204
uniprot id: H2M8R0
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

8090:LOC101171286
gene id: 8090:LOC101171286
uniprot id: H2LW87
names: Subcellular Location Annotation
messages: sarcolemma

8090:pgm3
gene id: 8090:pgm3
uniprot id: H2MR65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

8090:LOC101167609
gene id: 8090:LOC101167609
uniprot id: H2L581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:LOC101165907
gene id: 8090:LOC101165907
uniprot id: A0A3B3HRL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8090:LOC101169415
gene id: 8090:LOC101169415
uniprot id: H2LCN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

8090:LOC101168991
gene id: 8090:LOC101168991
uniprot id: A0A3P9LRL8
uniprot id: H2M3W6
names: Subcellular Location Annotation
messages: Z line

8090:LOC101174676
gene id: 8090:LOC101174676
uniprot id: H2MPB5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

8090:LOC101170540
gene id: 8090:LOC101170540
uniprot id: H2LN16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101157798
gene id: 8090:LOC101157798
uniprot id: A0A3B3I3L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

8090:LOC101159347
gene id: 8090:LOC101159347
uniprot id: A0A3P9J8G1
uniprot id: H2LDN9
names: Subcellular Location Annotation
messages: Nucleus

8090:siat8c2
gene id: 8090:siat8c2
uniprot id: A0A3P9KT48
uniprot id: Q5K020
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:b4gat1
gene id: 8090:b4gat1
uniprot id: H2LV64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:mmp24
gene id: 8090:mmp24
uniprot id: Q98TF2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:chaf1b
gene id: 8090:chaf1b
uniprot id: H2MUF8
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101175636
gene id: 8090:LOC101175636
uniprot id: H2LB02
names: Subcellular Location Annotation
messages: Membrane

8090:cmc1
gene id: 8090:cmc1
uniprot id: H2LL77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

8090:LOC101156641
gene id: 8090:LOC101156641
uniprot id: H2LCT6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

8090:cdc37l1
gene id: 8090:cdc37l1
uniprot id: A0A3B3I328
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

8090:phb
gene id: 8090:phb
uniprot id: H2LDB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

8090:LOC101164090
gene id: 8090:LOC101164090
uniprot id: H2LKJ8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:LOC101166254
gene id: 8090:LOC101166254
uniprot id: A0A3B3IGG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

8090:LOC101161903
gene id: 8090:LOC101161903
uniprot id: A0A3P9L1P7
uniprot id: H2LZS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

8090:slc30a9
gene id: 8090:slc30a9
uniprot id: A0A3B3HQT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

8090:LOC101174762
gene id: 8090:LOC101174762
uniprot id: H2LPF5
names: Similarity
messages: Belongs to the peptidase C14A family.

8090:npepl1
gene id: 8090:npepl1
uniprot id: H2MIF7
names: Similarity
messages: Belongs to the peptidase M17 family.

8090:dact3
gene id: 8090:dact3
uniprot id: A0A3B3I3G4
names: Similarity
messages: Belongs to the dapper family.

8090:LOC101175150
gene id: 8090:LOC101175150
uniprot id: H2MQ54
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:fam193b
gene id: 8090:fam193b
uniprot id: H2LQM4
names: Similarity
messages: Belongs to the FAM193 family.

8090:fam192a
gene id: 8090:fam192a
uniprot id: H2MDN8
uniprot id: H2MDP2
names: Subcellular Location Annotation
messages: Nucleus

8090:mrps7
gene id: 8090:mrps7
uniprot id: A0A3P9MFG0
uniprot id: H2M183
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

8090:vps4b
gene id: 8090:vps4b
uniprot id: H2MQM6
names: Similarity
messages: Belongs to the AAA ATPase family.

8090:piwil1
gene id: 8090:piwil1
uniprot id: A0A3P9LMZ1
uniprot id: B9U223
names: Similarity
messages: Belongs to the argonaute family.

8090:kdm1b
gene id: 8090:kdm1b
uniprot id: H2LUC1
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8090:rpl4
gene id: 8090:rpl4
uniprot id: H2LRE6
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

8090:LOC101160889
gene id: 8090:LOC101160889
uniprot id: A0A3P9IQJ7
uniprot id: H2M631
names: Similarity
messages: Belongs to the EVA1 family.

8090:LOC101169072
gene id: 8090:LOC101169072
uniprot id: A0A3P9M1P7
uniprot id: H2LVT0
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

8090:LOC101161751
gene id: 8090:LOC101161751
uniprot id: A0A3B3H6M7
names: Similarity
messages: Belongs to the canopy family.

8090:pax3
gene id: 8090:pax3
uniprot id: A0A3B3H8X6
uniprot id: A0A3B3IDW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8090:pik3cd
gene id: 8090:pik3cd
uniprot id: A0A3B3IIX4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8090:c4b
gene id: 8090:c4b
uniprot id: Q9IBG9
names: Subcellular Location Annotation
messages: Secreted

8090:LOC101174098
gene id: 8090:LOC101174098
uniprot id: A0A3B3HPI3
uniprot id: A0A3P9LF63
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8090:edc4
gene id: 8090:edc4
uniprot id: H2MBT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

8090:slc23a1
gene id: 8090:slc23a1
uniprot id: H2MBJ3
names: Subcellular Location Annotation
messages: Membrane

8090:cflar
gene id: 8090:cflar
uniprot id: D6BU25
names: Similarity
messages: Belongs to the peptidase C14A family.

8090:st6gal1
gene id: 8090:st6gal1
uniprot id: A0A3B3I8W4
uniprot id: Q5K028
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:mok
gene id: 8090:mok
uniprot id: H2MBQ7
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:postn
gene id: 8090:postn
uniprot id: A0A024F982
uniprot id: H2LET9
names: Subcellular Location Annotation
messages: extracellular matrix

8090:LOC101166121
gene id: 8090:LOC101166121
uniprot id: A0A3B3ICZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8090:LOC101162425
gene id: 8090:LOC101162425
uniprot id: H2LJG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

8090:LOC101159524
gene id: 8090:LOC101159524
uniprot id: H2LA48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:tryp
gene id: 8090:tryp
uniprot id: A4UWM7
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101168243
gene id: 8090:LOC101168243
uniprot id: H2MS48
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101158354
gene id: 8090:LOC101158354
uniprot id: H2LBM7
names: Similarity
messages: Belongs to the OSBP family.

8090:htr2b
gene id: 8090:htr2b
uniprot id: H2LTN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

8090:atp1b4
gene id: 8090:atp1b4
uniprot id: A0A3P9K3Q4
uniprot id: H2L678
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

8090:LOC101164972
gene id: 8090:LOC101164972
uniprot id: H2LMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8090:nkx2-5
gene id: 8090:nkx2-5
uniprot id: A2TJL6
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101159737
gene id: 8090:LOC101159737
uniprot id: A0A3B3I975
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8090:LOC101169661
gene id: 8090:LOC101169661
uniprot id: H2LCU3
names: Similarity
messages: Belongs to the pellino family.

8090:psmc4
gene id: 8090:psmc4
uniprot id: H2MQL0
names: Similarity
messages: Belongs to the AAA ATPase family.

8090:LOC101159547
gene id: 8090:LOC101159547
uniprot id: A0A3P9I1Z2
uniprot id: H2MSX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins.
messages: Nucleus

8090:LOC101165456
gene id: 8090:LOC101165456
uniprot id: H2MEM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

8090:ap1s3
gene id: 8090:ap1s3
uniprot id: A0A3B3H9X7
uniprot id: A0A3P9IPD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8090:exoc3l4
gene id: 8090:exoc3l4
uniprot id: A0A3B3I516
names: Similarity
messages: Belongs to the SEC6 family.

8090:ucma
gene id: 8090:ucma
uniprot id: A0A3B3HFI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

8090:arr3
gene id: 8090:arr3
uniprot id: O42104
names: Similarity
messages: Belongs to the arrestin family.

8090:bbs2
gene id: 8090:bbs2
uniprot id: A0A3B3IGF9
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

8090:emc2
gene id: 8090:emc2
uniprot id: A0A3B3IMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

8090:LOC101158219
gene id: 8090:LOC101158219
uniprot id: A0A3B3IB28
uniprot id: A0A3P9GYL7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

8090:LOC101174699
gene id: 8090:LOC101174699
uniprot id: A0A3B3I536
uniprot id: A0A3P9L3R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

8090:spic
gene id: 8090:spic
uniprot id: A0A3B3H922
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:pcsk5
gene id: 8090:pcsk5
uniprot id: A0A3B3HF70
names: Similarity
messages: Belongs to the peptidase S8 family.

8090:LOC101172187
gene id: 8090:LOC101172187
uniprot id: A0A3P9H4N3
uniprot id: H2LCF7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

8090:ddost
gene id: 8090:ddost
uniprot id: H2MYG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

8090:LOC101158931
gene id: 8090:LOC101158931
uniprot id: H2MGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8090:alg10
gene id: 8090:alg10
uniprot id: H2MXS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Membrane

8090:sufu
gene id: 8090:sufu
uniprot id: A0A3P9JZM9
uniprot id: H2LX77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Nucleus

8090:LOC101162460
gene id: 8090:LOC101162460
uniprot id: H2L783
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8090:snx10
gene id: 8090:snx10
uniprot id: H2LU49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

8090:fign
gene id: 8090:fign
uniprot id: A0A3B3IAN2
names: Similarity
messages: Belongs to the AAA ATPase family.

8090:LOC101169170
gene id: 8090:LOC101169170
uniprot id: A0A3P9MNP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:rarb
gene id: 8090:rarb
uniprot id: H2LHL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8090:isyna1
gene id: 8090:isyna1
uniprot id: H2MGD4
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

8090:homer1
gene id: 8090:homer1
uniprot id: H2LB09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

8090:tbp
gene id: 8090:tbp
uniprot id: C0SQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

8090:nsrp1
gene id: 8090:nsrp1
uniprot id: H2LDA2
names: Similarity
messages: Belongs to the NSRP1 family.

8090:nudt21
gene id: 8090:nudt21
uniprot id: A0A3P9HAE4
uniprot id: H2LY23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

8090:LOC101160681
gene id: 8090:LOC101160681
uniprot id: H2LQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8090:foxg1
gene id: 8090:foxg1
uniprot id: A0A3P9JWX2
uniprot id: C1K2Z3
names: Subcellular Location Annotation
messages: Nucleus

8090:lpcat1
gene id: 8090:lpcat1
uniprot id: A0A3B3H8R0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8090:LOC101160195
gene id: 8090:LOC101160195
uniprot id: A0A3B3HK62
uniprot id: A0A3P9I3T0
names: Similarity
messages: Belongs to the cornifelin family.

8090:LOC101158402
gene id: 8090:LOC101158402
uniprot id: H2MV92
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8090:mipep
gene id: 8090:mipep
uniprot id: H2MCK5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

8090:hddc2
gene id: 8090:hddc2
uniprot id: H2MRE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

8090:ccny
gene id: 8090:ccny
uniprot id: A0A3B3H3P3
uniprot id: A0A3B3HER6
uniprot id: A0A3B3HVI4
uniprot id: A0A3P9H6V8
uniprot id: A0A3P9H7N8
uniprot id: A0A3P9LY58
uniprot id: A0A3P9LYV0
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8090:scg3
gene id: 8090:scg3
uniprot id: H2LCU0
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

8090:anapc11
gene id: 8090:anapc11
uniprot id: A0A3B3HJT6
uniprot id: A0A3P9MD01
names: Similarity
messages: Belongs to the RING-box family.

8090:tardbp
gene id: 8090:tardbp
uniprot id: A0A3B3I3X8
uniprot id: A0A3P9H8Z3
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101165555
gene id: 8090:LOC101165555
uniprot id: A0A3B3I4W8
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101168720
gene id: 8090:LOC101168720
uniprot id: H2LS52
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

8090:tmem131
gene id: 8090:tmem131
uniprot id: H2MLY1
names: Similarity
messages: Belongs to the TMEM131 family.

8090:itga10
gene id: 8090:itga10
uniprot id: H2M360
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

8090:pde4b
gene id: 8090:pde4b
uniprot id: A0A3P9M524
uniprot id: H2M1L4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8090:LOC100049332
gene id: 8090:LOC100049332
uniprot id: Q9W7E3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

8090:LOC101168657
gene id: 8090:LOC101168657
uniprot id: A0A3B3IEU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

8090:chac2
gene id: 8090:chac2
uniprot id: A0A3B3H7V2
uniprot id: A0A3P9K6G3
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

8090:mrto4
gene id: 8090:mrto4
uniprot id: A0A3B3IIZ4
uniprot id: A0A3P9JFS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

8090:LOC101160490
gene id: 8090:LOC101160490
uniprot id: A0A3B3I305
uniprot id: A0A3P9JP42
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

8090:LOC101163059
gene id: 8090:LOC101163059
uniprot id: A0A3B3H8I6
names: Similarity
messages: Belongs to the HEBP family.

8090:ccna2
gene id: 8090:ccna2
uniprot id: H2N0K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8090:steap4
gene id: 8090:steap4
uniprot id: H2LX07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

8090:fut11
gene id: 8090:fut11
uniprot id: Q5F2N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

8090:LOC101163147
gene id: 8090:LOC101163147
uniprot id: A0A3B3HT13
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101175036
gene id: 8090:LOC101175036
uniprot id: H2MUL0
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101159227
gene id: 8090:LOC101159227
uniprot id: H2LLH2
names: Similarity
messages: Belongs to the SMARCD family.

8090:fgf20a
gene id: 8090:fgf20a
uniprot id: A0A3P9MJC8
uniprot id: Q0KJ03
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8090:LOC101161661
gene id: 8090:LOC101161661
uniprot id: H2LWG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8090:acad8
gene id: 8090:acad8
uniprot id: H2LKM2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8090:LOC101170994
gene id: 8090:LOC101170994
uniprot id: A0A3B3I6M2
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

8090:LOC101159768
gene id: 8090:LOC101159768
uniprot id: A0A3B3HGU9
uniprot id: A0A3P9LMK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:rps24
gene id: 8090:rps24
uniprot id: Q9W6X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Component of the small ribosomal subunit.
messages: Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.
messages: Cytoplasm

8090:olfm3
gene id: 8090:olfm3
uniprot id: H2LLZ9
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

8090:LOC101168379
gene id: 8090:LOC101168379
uniprot id: A0A3B3I5A5
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

8090:LOC101171151
gene id: 8090:LOC101171151
uniprot id: A0A3B3H5R4
uniprot id: A0A3P9MP13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

8090:LOC101165151
gene id: 8090:LOC101165151
uniprot id: A0A3B3IFS5
names: Similarity
messages: Belongs to the arrestin family.

8090:mertk
gene id: 8090:mertk
uniprot id: A0A3B3IG08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

8090:sh3bgrl3
gene id: 8090:sh3bgrl3
uniprot id: A0A3B3HVQ6
uniprot id: A0A3P9J6Z2
names: Similarity
messages: Belongs to the SH3BGR family.

8090:LOC101163261
gene id: 8090:LOC101163261
uniprot id: H2LG71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

8090:slc7a2
gene id: 8090:slc7a2
uniprot id: H2M2U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8090:LOC101156989
gene id: 8090:LOC101156989
uniprot id: H2LWR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

8090:pms2
gene id: 8090:pms2
uniprot id: H2LEG9
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

8090:cadm4
gene id: 8090:cadm4
uniprot id: A0A3B3H6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nectin family.
messages: Membrane

8090:tmem189
gene id: 8090:tmem189
uniprot id: A0A3B3IM17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

8090:LOC101173695
gene id: 8090:LOC101173695
uniprot id: H2MHR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:me2
gene id: 8090:me2
uniprot id: A0A3P9MN56
uniprot id: H2LJ68
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

8090:ddx47
gene id: 8090:ddx47
uniprot id: H2MJI0
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

8090:rad21
gene id: 8090:rad21
uniprot id: Q765Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

8090:atg5
gene id: 8090:atg5
uniprot id: Q3MQ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

8090:LOC101169687
gene id: 8090:LOC101169687
uniprot id: H2LP41
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

8090:ptgis
gene id: 8090:ptgis
uniprot id: H2L4V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8090:trdn
gene id: 8090:trdn
uniprot id: A0A3B3I4K1
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8090:LOC101161566
gene id: 8090:LOC101161566
uniprot id: H2LT25
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

8090:slc35f6
gene id: 8090:slc35f6
uniprot id: H2M9C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

8090:lhx4
gene id: 8090:lhx4
uniprot id: A0A3P9HL20
uniprot id: H2MSH3
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101164345
gene id: 8090:LOC101164345
uniprot id: H2MDH4
names: Similarity
messages: Belongs to the RRM TRSPAP family.

8090:LOC101170788
gene id: 8090:LOC101170788
uniprot id: H2LPB8
names: Subcellular Location Annotation
messages: extracellular space

8090:zdhhc2
gene id: 8090:zdhhc2
uniprot id: A0A3B3HEJ7
uniprot id: A0A3P9HYQ4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:LOC101166632
gene id: 8090:LOC101166632
uniprot id: A0A3B3IKQ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101164738
gene id: 8090:LOC101164738
uniprot id: A0A3B3INJ4
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155008
gene id: 8090:LOC101155008
uniprot id: A0A3P9LBA5
uniprot id: A0A3P9LBC1
uniprot id: A0A3P9LBE2
uniprot id: A0A3P9LBM9
uniprot id: H2LS88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8090:fopnl
gene id: 8090:fopnl
uniprot id: H2ME46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

8090:nup107
gene id: 8090:nup107
uniprot id: H2MRW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

8090:ppp1r21
gene id: 8090:ppp1r21
uniprot id: H2M5Q5
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8090:LOC101165530
gene id: 8090:LOC101165530
uniprot id: A0A3B3H9R4
names: Subcellular Location Annotation
messages: Membrane

8090:snw1
gene id: 8090:snw1
uniprot id: A0A3B3IES7
uniprot id: A0A3P9LBQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

8090:LOC101175152
gene id: 8090:LOC101175152
uniprot id: A0A3B3IA63
names: Similarity
messages: Belongs to the SAPS family.

8090:LOC101163818
gene id: 8090:LOC101163818
uniprot id: H2LGU4
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:LOC101159018
gene id: 8090:LOC101159018
uniprot id: H2LKV1
names: Similarity
messages: Belongs to the globin family.

8090:LOC101157624
gene id: 8090:LOC101157624
uniprot id: H2ML45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

8090:LOC101161519
gene id: 8090:LOC101161519
uniprot id: A0A3B3IIR1
names: Similarity
messages: Belongs to the LRRFIP family.

8090:LOC101173375
gene id: 8090:LOC101173375
uniprot id: A0A3B3H9U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

8090:mtmr6
gene id: 8090:mtmr6
uniprot id: H2LRH7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8090:nkx6-3
gene id: 8090:nkx6-3
uniprot id: A0A3B3IHV1
names: Subcellular Location Annotation
messages: Nucleus

8090:chd2
gene id: 8090:chd2
uniprot id: A0A3B3IJW2
uniprot id: H2LWR3
names: Subcellular Location Annotation
messages: Nucleus

8090:erbb4
gene id: 8090:erbb4
uniprot id: H2MMW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8090:slc7a4
gene id: 8090:slc7a4
uniprot id: A0A3P9LPX5
uniprot id: H2MCU0
names: Subcellular Location Annotation
messages: Membrane

8090:akirin1
gene id: 8090:akirin1
uniprot id: H2MIN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

8090:LOC101168921
gene id: 8090:LOC101168921
uniprot id: A0A3B3HC03
uniprot id: A0A3P9KP58
names: Similarity
messages: Belongs to the actin family.

8090:LOC101159417
gene id: 8090:LOC101159417
uniprot id: A0A024FS16
uniprot id: H2M3A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

8090:LOC101158634
gene id: 8090:LOC101158634
uniprot id: H2LV52
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8090:lag3
gene id: 8090:lag3
uniprot id: A0A3B3HSU0
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101175309
gene id: 8090:LOC101175309
uniprot id: A0A3B3HZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:ngrn
gene id: 8090:ngrn
uniprot id: H2LNI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

8090:bmp3
gene id: 8090:bmp3
uniprot id: H2MTZ7
names: Similarity
messages: Belongs to the TGF-beta family.

8090:acsl1
gene id: 8090:acsl1
uniprot id: H2LXK0
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8090:galc
gene id: 8090:galc
uniprot id: H2M5M9
uniprot id: H2M5N1
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

8090:LOC101159320
gene id: 8090:LOC101159320
uniprot id: H2LF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

8090:LOC101157887
gene id: 8090:LOC101157887
uniprot id: A0A3B3HVK5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:olgc5
gene id: 8090:olgc5
uniprot id: Q9W616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8090:LOC101165153
gene id: 8090:LOC101165153
uniprot id: H2LEK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

8090:pigk
gene id: 8090:pigk
uniprot id: H2LDV7
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.

8090:lrfn1
gene id: 8090:lrfn1
uniprot id: H2LK20
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101170140
gene id: 8090:LOC101170140
uniprot id: A0A3P9KES0
uniprot id: H2ML15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:LOC101162162
gene id: 8090:LOC101162162
uniprot id: H2LZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8090:ppp1cc
gene id: 8090:ppp1cc
uniprot id: A0A3P9HPM6
uniprot id: H2MML8
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

8090:LOC101164680
gene id: 8090:LOC101164680
uniprot id: A0A3P9K8X2
names: Similarity
messages: Belongs to the SNF7 family.

8090:LOC101168213
gene id: 8090:LOC101168213
uniprot id: H2LIC3
names: Similarity
messages: Belongs to the Bcl-2 family.

8090:uba2
gene id: 8090:uba2
uniprot id: H2MB35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

8090:lox
gene id: 8090:lox
uniprot id: H2MRQ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8090:LOC101168303
gene id: 8090:LOC101168303
uniprot id: A0A3B3HA99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

8090:rsg1
gene id: 8090:rsg1
uniprot id: H2LEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

8090:slc25a40
gene id: 8090:slc25a40
uniprot id: H2LZZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:LOC101164686
gene id: 8090:LOC101164686
uniprot id: H2M840
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

8090:LOC101170539
gene id: 8090:LOC101170539
uniprot id: A0A3B3I5N9
uniprot id: A0A3P9MMF2
names: Similarity
messages: Belongs to the exportin family.

8090:pde3b
gene id: 8090:pde3b
uniprot id: A0A3B3HP53
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8090:farsb
gene id: 8090:farsb
uniprot id: H2LYY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

8090:ptdss2
gene id: 8090:ptdss2
uniprot id: H2L9P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:cltb
gene id: 8090:cltb
uniprot id: A0A3B3HEE1
uniprot id: A0A3B3HGV6
uniprot id: A0A3B3HXT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

8090:krtcap2
gene id: 8090:krtcap2
uniprot id: A0A3B3HRU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

8090:LOC101170991
gene id: 8090:LOC101170991
uniprot id: A0A3B3IGP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8090:pik3c2b
gene id: 8090:pik3c2b
uniprot id: H2M4Z3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8090:LOC101156566
gene id: 8090:LOC101156566
uniprot id: H2MJ14
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101160286
gene id: 8090:LOC101160286
uniprot id: A0A3B3H7G5
names: Similarity
messages: Belongs to the HEBP family.

8090:LOC101156182
gene id: 8090:LOC101156182
uniprot id: H2M221
names: Similarity
messages: Belongs to the intermediate filament family.

8090:LOC101155672
gene id: 8090:LOC101155672
uniprot id: A0A3P9MQB2
names: Similarity
messages: Belongs to the guanylate kinase family.

8090:ugdh
gene id: 8090:ugdh
uniprot id: A0A3B3HED3
uniprot id: A0A3P9H5M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

8090:luc7l
gene id: 8090:luc7l
uniprot id: H2LVQ0
names: Similarity
messages: Belongs to the Luc7 family.

8090:LOC101158790
gene id: 8090:LOC101158790
uniprot id: A0A3P9LGU7
uniprot id: H2M2X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8090:LOC101171110
gene id: 8090:LOC101171110
uniprot id: H2LF83
names: Similarity
messages: Belongs to the TMEM14 family.

8090:zfpm1
gene id: 8090:zfpm1
uniprot id: A0A3B3HCR0
names: Subcellular Location Annotation
messages: Nucleus

8090:kfharr-r2
gene id: 8090:kfharr-r2
uniprot id: A0A3B3HC59
uniprot id: A0A3P9I9U1
uniprot id: A0A3P9IAA3
uniprot id: Q9W7R1
names: Similarity
messages: Belongs to the arrestin family.

8090:LOC101158206
gene id: 8090:LOC101158206
uniprot id: H2MTE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
messages: cytoskeleton

8090:slc16a1
gene id: 8090:slc16a1
uniprot id: A0A3B3HZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8090:trdmt1
gene id: 8090:trdmt1
uniprot id: A0A3B3I1L5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

8090:LOC101170932
gene id: 8090:LOC101170932
uniprot id: H2LB31
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

8090:LOC101174571
gene id: 8090:LOC101174571
uniprot id: A0A3P9L301
uniprot id: H2MXA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

8090:mal2
gene id: 8090:mal2
uniprot id: A0A3B3HIQ4
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101160191
gene id: 8090:LOC101160191
uniprot id: H2LUU4
names: Similarity
messages: Belongs to the MAGUK family.

8090:cacng2
gene id: 8090:cacng2
uniprot id: A0A3B3H9L8
uniprot id: A0A3P9HG36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

8090:LOC101174186
gene id: 8090:LOC101174186
uniprot id: Q3V609
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101157087
gene id: 8090:LOC101157087
uniprot id: A0A3B3H2X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8090:LOC101171520
gene id: 8090:LOC101171520
uniprot id: A0A3P9KBF2
uniprot id: H2MCG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

8090:ethe1
gene id: 8090:ethe1
uniprot id: H2MK55
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8090:LOC101157252
gene id: 8090:LOC101157252
uniprot id: A0A3B3H3U6
names: Subcellular Location Annotation
messages: Membrane

8090:g2e3
gene id: 8090:g2e3
uniprot id: H2M3Y0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101166344
gene id: 8090:LOC101166344
uniprot id: A0A3B3IJ67
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

8090:golm1
gene id: 8090:golm1
uniprot id: H2LL55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

8090:nubpl
gene id: 8090:nubpl
uniprot id: H2MUZ8
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

8090:LOC101164688
gene id: 8090:LOC101164688
uniprot id: H2MDW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101160557
gene id: 8090:LOC101160557
uniprot id: A0A3B3IH74
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

8090:LOC101171421
gene id: 8090:LOC101171421
uniprot id: A0A3B3HE72
uniprot id: A0A3P9LEM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

8090:slc22a18
gene id: 8090:slc22a18
uniprot id: H2L2R7
names: Subcellular Location Annotation
messages: Membrane

8090:src
gene id: 8090:src
uniprot id: A0A3P9HKN8
uniprot id: A0A3P9J4Q9
uniprot id: H2LQT6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8090:LOC101163810
gene id: 8090:LOC101163810
uniprot id: H2MNT4
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

8090:rnft1
gene id: 8090:rnft1
uniprot id: A0A3B3I2T7
names: Subcellular Location Annotation
messages: Membrane

8090:arl2bp
gene id: 8090:arl2bp
uniprot id: H2ML56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.
messages: centrosome
messages: cilium basal body

8090:LOC101165013
gene id: 8090:LOC101165013
uniprot id: A0A3B3HFH2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:smug1
gene id: 8090:smug1
uniprot id: H2MKL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

8090:fbln1
gene id: 8090:fbln1
uniprot id: H2M6D0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8090:gba2
gene id: 8090:gba2
uniprot id: A0A3B3HCE5
names: Function
names: Similarity
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

8090:b3galt1
gene id: 8090:b3galt1
uniprot id: H2MRB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101167911
gene id: 8090:LOC101167911
uniprot id: A0A3B3H5D5
uniprot id: A0A3P9KTP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC105354544
gene id: 8090:LOC105354544
uniprot id: H2LQZ1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

8090:vangl2
gene id: 8090:vangl2
uniprot id: H2LCD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

8090:mfn1
gene id: 8090:mfn1
uniprot id: H2LMV4
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

8090:LOC105357959
gene id: 8090:LOC105357959
uniprot id: A0A3P9MNP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:pex13
gene id: 8090:pex13
uniprot id: H2L809
names: Similarity
messages: Belongs to the peroxin-13 family.

8090:ddx41
gene id: 8090:ddx41
uniprot id: A0A3P9KGG2
uniprot id: H2LQQ1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

8090:tmem147
gene id: 8090:tmem147
uniprot id: A0A3P9MKE0
uniprot id: H2LND7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM147 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:nup210
gene id: 8090:nup210
uniprot id: A0A3B3I7Z4
names: Similarity
messages: Belongs to the NUP210 family.

8090:trmt61a
gene id: 8090:trmt61a
uniprot id: H2MUE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

8090:LOC101163424
gene id: 8090:LOC101163424
uniprot id: A0A3P9L1R1
uniprot id: H2L7H2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8090:iars2
gene id: 8090:iars2
uniprot id: A0A3B3HRZ1
uniprot id: H2MU37
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8090:KEF90 p13
gene id: 8090:KEF90_p13
uniprot id: Q8HLX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

8090:ndufa8
gene id: 8090:ndufa8
uniprot id: H2M234
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

8090:LOC101156845
gene id: 8090:LOC101156845
uniprot id: A0A3P9M1X0
uniprot id: H2M287
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

8090:pcyox1l
gene id: 8090:pcyox1l
uniprot id: H2LAS6
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

8090:cdr2
gene id: 8090:cdr2
uniprot id: A0A3B3HX01
names: Similarity
messages: Belongs to the CDR2 family.

8090:leprot
gene id: 8090:leprot
uniprot id: A0A3B3HLV3
uniprot id: A0A3P9HB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

8090:eme2
gene id: 8090:eme2
uniprot id: A0A3B3H9B3
names: Similarity
messages: Belongs to the EME1/MMS4 family.

8090:LOC101162228
gene id: 8090:LOC101162228
uniprot id: H2LSG9
names: Similarity
messages: Belongs to the FXYD family.

8090:LOC101160603
gene id: 8090:LOC101160603
uniprot id: A0A3B3I1B9
uniprot id: A0A3P9J082
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8090:ech1
gene id: 8090:ech1
uniprot id: H2L4Y0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8090:LOC101167994
gene id: 8090:LOC101167994
uniprot id: A0A3P9KLE4
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101159957
gene id: 8090:LOC101159957
uniprot id: A0A3B3I2Q1
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8090:pik3cg
gene id: 8090:pik3cg
uniprot id: H2M0C9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

8090:LOC101166894
gene id: 8090:LOC101166894
uniprot id: H2MLH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

8090:LOC101165430
gene id: 8090:LOC101165430
uniprot id: A0A3B3ILA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101159015
gene id: 8090:LOC101159015
uniprot id: H2LDW4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

8090:LOC101158393
gene id: 8090:LOC101158393
uniprot id: H2LQD5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:LOC101168170
gene id: 8090:LOC101168170
uniprot id: A0A3B3IN81
names: Similarity
messages: Belongs to the FAX family.

8090:LOC101164541
gene id: 8090:LOC101164541
uniprot id: B3TZ93
names: Subcellular Location Annotation
messages: Membrane

8090:bsg
gene id: 8090:bsg
uniprot id: H2LHD2
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101170748
gene id: 8090:LOC101170748
uniprot id: A0A3B3IJL5
uniprot id: A0A3P9LIH8
names: Similarity
messages: Belongs to the pyruvate kinase family.

8090:arpp19
gene id: 8090:arpp19
uniprot id: A0A3B3I9Y7
uniprot id: A0A3P9M511
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

8090:tmbim6
gene id: 8090:tmbim6
uniprot id: A0A3P9IK30
uniprot id: H2MPP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8090:emp1
gene id: 8090:emp1
uniprot id: A0A3B3IK50
uniprot id: A0A3P9KA15
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:fgg
gene id: 8090:fgg
uniprot id: A0A455U065
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

8090:LOC101170094
gene id: 8090:LOC101170094
uniprot id: A0A3P9M6F5
uniprot id: H2MIH5
names: Similarity
messages: Belongs to the PPDPF family.

8090:LOC101170846
gene id: 8090:LOC101170846
uniprot id: A0A3B3HMZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

8090:LOC101166056
gene id: 8090:LOC101166056
uniprot id: H2MES6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

8090:podxl2
gene id: 8090:podxl2
uniprot id: A0A3B3I2H7
names: Subcellular Location Annotation
messages: Membrane

8090:kdm5c
gene id: 8090:kdm5c
uniprot id: A0A3B3HVI5
uniprot id: H2MHA4
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

8090:mapkap1
gene id: 8090:mapkap1
uniprot id: H2MDF4
names: Similarity
messages: Belongs to the SIN1 family.

8090:LOC101163027
gene id: 8090:LOC101163027
uniprot id: H2LVQ1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:LOC101165887
gene id: 8090:LOC101165887
uniprot id: H2MR29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:tob1
gene id: 8090:tob1
uniprot id: A0A3P9L166
names: Similarity
messages: Belongs to the BTG family.

8090:LOC101175398
gene id: 8090:LOC101175398
uniprot id: A0A3B3H8G9
uniprot id: A0A3P9LG43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101158643
gene id: 8090:LOC101158643
uniprot id: H2MB37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8090:hsf5
gene id: 8090:hsf5
uniprot id: A0A3B3ICS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

8090:kcnj3
gene id: 8090:kcnj3
uniprot id: A0A3P9LL30
uniprot id: H2MQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

8090:ppcs
gene id: 8090:ppcs
uniprot id: H2LGA7
names: Similarity
messages: Belongs to the PPC synthetase family.

8090:LOC101170109
gene id: 8090:LOC101170109
uniprot id: A0A3P9MHF1
uniprot id: H2M3A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

8090:LOC101159436
gene id: 8090:LOC101159436
uniprot id: H2LW65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:sox1
gene id: 8090:sox1
uniprot id: C3VV06
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101169703
gene id: 8090:LOC101169703
uniprot id: A0A3P9IH30
uniprot id: H2MEE0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:LOC101160972
gene id: 8090:LOC101160972
uniprot id: A0A3B3H7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8090:LOC105353996
gene id: 8090:LOC105353996
uniprot id: H2MJ83
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101160000
gene id: 8090:LOC101160000
uniprot id: H2MTW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:nmt2
gene id: 8090:nmt2
uniprot id: A0A3P9I9L0
uniprot id: H2LZI6
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

8090:cdk7
gene id: 8090:cdk7
uniprot id: A0A3P9M523
uniprot id: H2LY76
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

8090:LOC101173915
gene id: 8090:LOC101173915
uniprot id: H2LCB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:haus3
gene id: 8090:haus3
uniprot id: H2LTV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

8090:mmd
gene id: 8090:mmd
uniprot id: A0A3P9L7K4
uniprot id: A0A3P9MHC9
uniprot id: H2L5T6
uniprot id: H2L5T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

8090:LOC101168232
gene id: 8090:LOC101168232
uniprot id: H2LB51
uniprot id: H2LCN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

8090:LOC101172718
gene id: 8090:LOC101172718
uniprot id: A0A3B3ICC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

8090:copz1
gene id: 8090:copz1
uniprot id: A0A3B3HXN9
uniprot id: A0A3P9JUF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

8090:LOC101162593
gene id: 8090:LOC101162593
uniprot id: A0A3B3I467
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:mrps12
gene id: 8090:mrps12
uniprot id: A0A3P9HLA1
uniprot id: H2LRY8
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

8090:rhpn1
gene id: 8090:rhpn1
uniprot id: H2MCZ3
names: Similarity
messages: Belongs to the RHPN family.

8090:il17d
gene id: 8090:il17d
uniprot id: E3WEB1
uniprot id: H2MCF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

8090:ahcyl1
gene id: 8090:ahcyl1
uniprot id: A0A3P9H4I5
uniprot id: A0A3P9ITX9
uniprot id: H2LNS1
uniprot id: H2LNS4
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

8090:LOC101166176
gene id: 8090:LOC101166176
uniprot id: H2MVA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

8090:dcn
gene id: 8090:dcn
uniprot id: A0A3B3I777
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

8090:LOC101155824
gene id: 8090:LOC101155824
uniprot id: A0A3P9I5H1
uniprot id: H2L385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:rpl30
gene id: 8090:rpl30
uniprot id: A0A3P9I382
uniprot id: H2MCZ2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

8090:rrp8
gene id: 8090:rrp8
uniprot id: A0A3B3ILD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Probable methyltransferase required to silence rDNA.
messages: nucleolus

8090:LOC101169133
gene id: 8090:LOC101169133
uniprot id: H2LNH1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

8090:LOC101155005
gene id: 8090:LOC101155005
uniprot id: H2LFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:sema5a
gene id: 8090:sema5a
uniprot id: A0A3B3ICI9
uniprot id: A0A3B3ICP9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101166162
gene id: 8090:LOC101166162
uniprot id: A0A3P9KBK4
uniprot id: H2M7R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

8090:adh5
gene id: 8090:adh5
uniprot id: Q6B4J3
uniprot id: Q6R5I9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

8090:slc5a2
gene id: 8090:slc5a2
uniprot id: H2LY03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8090:LOC101158137
gene id: 8090:LOC101158137
uniprot id: H2M5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:KEF90 p04
gene id: 8090:KEF90_p04
uniprot id: Q8HLW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

8090:naga
gene id: 8090:naga
uniprot id: H2MQT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

8090:itr1
gene id: 8090:itr1
uniprot id: H1ADE8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101157528
gene id: 8090:LOC101157528
uniprot id: H2MJ62
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC100125533
gene id: 8090:LOC100125533
uniprot id: H2MQ65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

8090:sema3a
gene id: 8090:sema3a
uniprot id: A0A3B3I1W5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:zenzai
gene id: 8090:zenzai
uniprot id: A0A3P9KTI0
uniprot id: C0STH5
names: Similarity
messages: Belongs to the CD36 family.

8090:LOC101166753
gene id: 8090:LOC101166753
uniprot id: A0A3B3IA83
uniprot id: H2LCP6
names: Subcellular Location Annotation
messages: Nucleus

8090:zmpste24
gene id: 8090:zmpste24
uniprot id: H2MI53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

8090:siat9
gene id: 8090:siat9
uniprot id: H2LUJ5
uniprot id: Q5ND63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:aasdh
gene id: 8090:aasdh
uniprot id: H2L982
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8090:LOC100301602
gene id: 8090:LOC100301602
uniprot id: C1K2Y1
names: Subcellular Location Annotation
messages: Nucleus

8090:gpr6
gene id: 8090:gpr6
uniprot id: A0A3P9HD58
uniprot id: H2MFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:slc50a1
gene id: 8090:slc50a1
uniprot id: H2N0X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101168707
gene id: 8090:LOC101168707
uniprot id: H2LBP5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:LOC101160175
gene id: 8090:LOC101160175
uniprot id: H2LLH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8090:riok2
gene id: 8090:riok2
uniprot id: H2LXK4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

8090:creld1
gene id: 8090:creld1
uniprot id: A0A3P9JGS6
uniprot id: H2M616
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:c15h10orf90
gene id: 8090:c15h10orf90
uniprot id: A0A3B3H926
names: Subcellular Location Annotation
messages: centrosome

8090:LOC101160491
gene id: 8090:LOC101160491
uniprot id: A0A3B3IKN6
uniprot id: A0A3P9JDS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8090:LOC101161306
gene id: 8090:LOC101161306
uniprot id: A0A3B3IDY5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:LOC101165777
gene id: 8090:LOC101165777
uniprot id: A0A3B3IIK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the podocalyxin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: filopodium
messages: lamellipodium
messages: microvillus
messages: ruffle

8090:actr6
gene id: 8090:actr6
uniprot id: A0A3B3ILF8
names: Similarity
messages: Belongs to the actin family.

8090:cldn15
gene id: 8090:cldn15
uniprot id: A0A3P9IWS3
uniprot id: H2LSC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8090:LOC101159307
gene id: 8090:LOC101159307
uniprot id: H2MSW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8090:LOC101163802
gene id: 8090:LOC101163802
uniprot id: A0A3P9L9S8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

8090:cbl
gene id: 8090:cbl
uniprot id: H2LTW9
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

8090:rbm47
gene id: 8090:rbm47
uniprot id: A0A3B3I822
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Cytoplasm
messages: Nucleus

8090:LOC101168512
gene id: 8090:LOC101168512
uniprot id: A0A3B3HDM5
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

8090:fzd9
gene id: 8090:fzd9
uniprot id: H2M7Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8090:LOC101156965
gene id: 8090:LOC101156965
uniprot id: H2MJ35
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:pkd2
gene id: 8090:pkd2
uniprot id: H2LRU7
names: Activity Regulation
names: Disruption Phenotype
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Basolateral cell membrane
messages: Belongs to the polycystin family.
messages: Cell membrane
messages: Channel activity is regulated by phosphorylation. Channel activity is regulated by intracellular Ca(2+).
messages: Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Can also form a functional, homotetrameric ion channel (By similarity). Functions as non-selective, voltage-gated cation channel. Required for normal oscillation of Ca(2+) levels within cilia; these oscillations of the intraciliary Ca(2+) levels can trigger cytoplasmic Ca(2+) signaling cascades (By similarity). May contribute to the release of Ca(2+) stores from the endoplasmic reticulum (By similarity). Plays a role in fluid-flow mechanosensation: forms a complex with pkd1l1 in cilia to facilitate flow detection in left/right patterning (PubMed:21307098). Required for normal specification of the body left-right axis during embryogenesis (PubMed:21307098).
messages: Cytoplasmic vesicle membrane
messages: Defects in left-right axis patterning.
messages: Endoplasmic reticulum membrane
messages: Homotetramer (By similarity). Heterotetramer with pkd1, giving rise to a complex formed by one pkd1 chain and three pkd2 chains (By similarity). Interacts with pkd1l1.
messages: N-glycosylated. The four subunits in a tetramer probably differ in the extent of glycosylation; simultaneous glycosylation of all experimentally validated sites would probably create steric hindrance.
messages: Phosphorylated. Phosphorylation is important for protein function; a mutant human construct that lacks the N-terminal phosphorylation sites cannot complement a zebrafish pkd2-deficient mutant.
messages: The C-terminal coiled-coil domain is involved in oligomerization. The coiled-coil domain binds calcium and undergoes a calcium-induced conformation change (in vitro).
messages: Ubiquitously expressed. Expressed in Kupffer's vesicle, an organ equivalent to the node.
messages: cilium membrane

8090:tnip2
gene id: 8090:tnip2
uniprot id: H2LWJ2
names: Subcellular Location Annotation
messages: Cytoplasm

8090:gpr12
gene id: 8090:gpr12
uniprot id: H2LY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101172426
gene id: 8090:LOC101172426
uniprot id: H2LCE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

8090:LOC101165146
gene id: 8090:LOC101165146
uniprot id: A0A3B3IM28
names: Similarity
messages: Belongs to the NATD1 family.

8090:cpa6
gene id: 8090:cpa6
uniprot id: H2LWE3
names: Similarity
messages: Belongs to the peptidase M14 family.

8090:LOC101165734
gene id: 8090:LOC101165734
uniprot id: A0A3B3HKH8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

8090:exoc7
gene id: 8090:exoc7
uniprot id: A0A3B3I5Z2
uniprot id: A0A3B3I6M6
uniprot id: A0A3B3ING9
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

8090:ing3
gene id: 8090:ing3
uniprot id: A0A3B3HXS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8090:LOC101159857
gene id: 8090:LOC101159857
uniprot id: H2MNR3
names: Similarity
messages: Belongs to the angiomotin family.

8090:hyls1
gene id: 8090:hyls1
uniprot id: A0A3B3IPX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

8090:LOC101174577
gene id: 8090:LOC101174577
uniprot id: A0A3B3IAB4
names: Subcellular Location Annotation
messages: Membrane

8090:tekt4
gene id: 8090:tekt4
uniprot id: H2M745
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8090:pld4
gene id: 8090:pld4
uniprot id: H2MRF1
names: Similarity
messages: Belongs to the phospholipase D family.

8090:pex5
gene id: 8090:pex5
uniprot id: A0A3B3HCI2
uniprot id: A0A3B3IIQ7
names: Similarity
messages: Belongs to the peroxisomal targeting signal receptor family.

8090:LOC101160743
gene id: 8090:LOC101160743
uniprot id: Q3V637
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC100049191
gene id: 8090:LOC100049191
uniprot id: Q9W646
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

8090:LOC101174445
gene id: 8090:LOC101174445
uniprot id: H2LW64
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8090:ap1s1
gene id: 8090:ap1s1
uniprot id: H2M3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8090:LOC101167714
gene id: 8090:LOC101167714
uniprot id: A0A3B3I2Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

8090:olgc3
gene id: 8090:olgc3
uniprot id: P79999
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8090:vps26c
gene id: 8090:vps26c
uniprot id: H2MGT3
names: Similarity
messages: Belongs to the VPS26 family.

8090:cutc
gene id: 8090:cutc
uniprot id: H2LWB3
names: Similarity
messages: Belongs to the CutC family.

8090:LOC101170529
gene id: 8090:LOC101170529
uniprot id: H2LZD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8090:fam131a
gene id: 8090:fam131a
uniprot id: A0A3B3H437
names: Similarity
messages: Belongs to the FAM131 family.

8090:cstf1
gene id: 8090:cstf1
uniprot id: H2M085
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101167169
gene id: 8090:LOC101167169
uniprot id: A0A3P9LGI6
uniprot id: H2MM95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:nr4a1
gene id: 8090:nr4a1
uniprot id: H2MKC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8090:LOC101168282
gene id: 8090:LOC101168282
uniprot id: H2M889
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

8090:gga3
gene id: 8090:gga3
uniprot id: H2M1C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

8090:LOC101161671
gene id: 8090:LOC101161671
uniprot id: H2LB91
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

8090:riox1
gene id: 8090:riox1
uniprot id: H2M7R3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

8090:LOC101164291
gene id: 8090:LOC101164291
uniprot id: H2M502
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101171254
gene id: 8090:LOC101171254
uniprot id: H2MMZ3
names: Subcellular Location Annotation
messages: Membrane

8090:mpp1
gene id: 8090:mpp1
uniprot id: H2M3C1
names: Similarity
messages: Belongs to the MAGUK family.

8090:rora
gene id: 8090:rora
uniprot id: A0A3B3HLR7
uniprot id: A0A3B3I839
uniprot id: A0A3P9IG92
uniprot id: A0A3P9JPB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8090:cmklr1
gene id: 8090:cmklr1
uniprot id: H2LRC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8090:LOC101167252
gene id: 8090:LOC101167252
uniprot id: A0A3B3IBL4
uniprot id: A0A3P9LS76
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

8090:LOC101166309
gene id: 8090:LOC101166309
uniprot id: H2MKW8
names: Similarity
messages: Belongs to the hexokinase family.

8090:kcne4
gene id: 8090:kcne4
uniprot id: A0A3B3HPK0
names: Similarity
messages: Belongs to the potassium channel KCNE family.

8090:zdhhc12
gene id: 8090:zdhhc12
uniprot id: H2MBI0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:copb2
gene id: 8090:copb2
uniprot id: A0A3B3HX48
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

8090:LOC101161496
gene id: 8090:LOC101161496
uniprot id: H2LS94
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:LOC101157435
gene id: 8090:LOC101157435
uniprot id: A0A3B3HK29
uniprot id: A0A3P9LG45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8090:LOC101168529
gene id: 8090:LOC101168529
uniprot id: A0A3P9JQS4
uniprot id: H2MC66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

8090:kfh-r
gene id: 8090:kfh-r
uniprot id: P87367
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.
messages: The color pigments are found in the cone photoreceptor cells.
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

8090:ywhaq
gene id: 8090:ywhaq
uniprot id: A0A3P9M4W1
uniprot id: H2MK95
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

8090:LOC101161489
gene id: 8090:LOC101161489
uniprot id: A0A3B3H482
uniprot id: A0A3P9IKS9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC101168433
gene id: 8090:LOC101168433
uniprot id: H2M257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

8090:vhl
gene id: 8090:vhl
uniprot id: A0A3B3HZK5
names: Similarity
messages: Belongs to the VHL family.

8090:cenpu
gene id: 8090:cenpu
uniprot id: H2LXF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

8090:pold2
gene id: 8090:pold2
uniprot id: A0A3B3HC50
uniprot id: A0A3P9LQX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

8090:LOC101156489
gene id: 8090:LOC101156489
uniprot id: H2MF27
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

8090:LOC101160023
gene id: 8090:LOC101160023
uniprot id: A0A3B3HD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

8090:coq7
gene id: 8090:coq7
uniprot id: H2MDX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.
messages: Mitochondrion inner membrane

8090:ccnb1
gene id: 8090:ccnb1
uniprot id: H2MEW8
uniprot id: Q9IBG1
names: Developmental Stage
names: Function
names: Similarity
names: Subunit
messages: Accumulates steadily during G2 and is abruptly destroyed at mitosis.
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex (By similarity).
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8090:LOC101171505
gene id: 8090:LOC101171505
uniprot id: A0A3P9LWW8
uniprot id: H2MBN9
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8090:LOC101174506
gene id: 8090:LOC101174506
uniprot id: H2LVL8
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101174125
gene id: 8090:LOC101174125
uniprot id: H2L4T1
names: Subcellular Location Annotation
messages: Nucleus

8090:stip1
gene id: 8090:stip1
uniprot id: H2M589
names: Subcellular Location Annotation
messages: Cytoplasm

8090:pcyox1
gene id: 8090:pcyox1
uniprot id: H2M0D5
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

8090:cntnap1
gene id: 8090:cntnap1
uniprot id: H2LHN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

8090:LOC101157602
gene id: 8090:LOC101157602
uniprot id: H2LTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

8090:zcchc8
gene id: 8090:zcchc8
uniprot id: H2LNA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

8090:LOC101161914
gene id: 8090:LOC101161914
uniprot id: H2LQ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

8090:st8sia1
gene id: 8090:st8sia1
uniprot id: Q5K022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:ino80c
gene id: 8090:ino80c
uniprot id: H2LXJ2
names: Subcellular Location Annotation
messages: Nucleus

8090:fam3c
gene id: 8090:fam3c
uniprot id: H2MK99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

8090:slc25a51
gene id: 8090:slc25a51
uniprot id: A0A3P9KWY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:LOC101161835
gene id: 8090:LOC101161835
uniprot id: A0A3B3IJN8
uniprot id: H2MU96
names: Similarity
messages: Belongs to the lipin family.

8090:LOC101165238
gene id: 8090:LOC101165238
uniprot id: H2MIF3
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

8090:hdx
gene id: 8090:hdx
uniprot id: H2LWY5
names: Subcellular Location Annotation
messages: Nucleus

8090:rhag
gene id: 8090:rhag
uniprot id: A0A3P9MCP5
uniprot id: H2MA30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8090:rps21
gene id: 8090:rps21
uniprot id: H2MXU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

8090:tnr
gene id: 8090:tnr
uniprot id: H2MNQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

8090:LOC101166982
gene id: 8090:LOC101166982
uniprot id: H2M971
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

8090:spo11
gene id: 8090:spo11
uniprot id: H2M801
names: Similarity
messages: Belongs to the TOP6A family.

8090:sub1
gene id: 8090:sub1
uniprot id: A0A3P9HBV6
uniprot id: Q68Y58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

8090:LOC101168184
gene id: 8090:LOC101168184
uniprot id: H2MG53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101164709
gene id: 8090:LOC101164709
uniprot id: A0A3P9JWG6
uniprot id: H2L7M9
names: Subcellular Location Annotation
messages: Cytoplasm

8090:slc6a4
gene id: 8090:slc6a4
uniprot id: H2MFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:pih1d2
gene id: 8090:pih1d2
uniprot id: A0A3B3HS41
uniprot id: A0A3B3I5X0
names: Similarity
messages: Belongs to the PIH1 family.

8090:atg13
gene id: 8090:atg13
uniprot id: H2LNJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

8090:thop1
gene id: 8090:thop1
uniprot id: A0A3B3IBU9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

8090:LOC101163714
gene id: 8090:LOC101163714
uniprot id: H2L3Q5
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

8090:LOC101155373
gene id: 8090:LOC101155373
uniprot id: A0A3B3I1I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

8090:LOC101172274
gene id: 8090:LOC101172274
uniprot id: A0A3B3H4N6
names: Subcellular Location Annotation
messages: Nucleus

8090:npm3
gene id: 8090:npm3
uniprot id: H2LX14
names: Similarity
messages: Belongs to the nucleoplasmin family.

8090:serinc5
gene id: 8090:serinc5
uniprot id: A0A3P9M5B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

8090:srd5a3
gene id: 8090:srd5a3
uniprot id: H2L4Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

8090:tmem2
gene id: 8090:tmem2
uniprot id: H2M515
names: Similarity
messages: Belongs to the CEMIP family.

8090:coq9
gene id: 8090:coq9
uniprot id: H2MJR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

8090:hebp3
gene id: 8090:hebp3
uniprot id: L0N757
names: Similarity
messages: Belongs to the HEBP family.

8090:mfsd6l
gene id: 8090:mfsd6l
uniprot id: A0A3B3HPN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

8090:ss18
gene id: 8090:ss18
uniprot id: H2MR58
uniprot id: H2MR59
uniprot id: H2MR60
names: Similarity
messages: Belongs to the SS18 family.

8090:ing1
gene id: 8090:ing1
uniprot id: A0A3P9M9S5
uniprot id: H2MUZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8090:dhcr7
gene id: 8090:dhcr7
uniprot id: H2MKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

8090:LOC101155318
gene id: 8090:LOC101155318
uniprot id: A0A3B3IA25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:LOC101167009
gene id: 8090:LOC101167009
uniprot id: A0A3B3HL85
names: Similarity
messages: Belongs to the uridine kinase family.

8090:stard3nl
gene id: 8090:stard3nl
uniprot id: H2LP55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Membrane

8090:ddx49
gene id: 8090:ddx49
uniprot id: H2LX42
names: Similarity
messages: Belongs to the DEAD box helicase family.

8090:irak4
gene id: 8090:irak4
uniprot id: H2LDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

8090:LOC101175057
gene id: 8090:LOC101175057
uniprot id: H2N009
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8090:LOC101155954
gene id: 8090:LOC101155954
uniprot id: H2LRH8
names: Subcellular Location Annotation
messages: Membrane

8090:spop
gene id: 8090:spop
uniprot id: A0A3P9MFI1
uniprot id: H2LLW4
names: Similarity
messages: Belongs to the Tdpoz family.

8090:LOC101163161
gene id: 8090:LOC101163161
uniprot id: A0A3P9K0P7
uniprot id: H2MCM8
names: Subcellular Location Annotation
messages: Membrane

8090:tmem14a
gene id: 8090:tmem14a
uniprot id: A0A3B3IG77
names: Similarity
messages: Belongs to the TMEM14 family.

8090:foxf1
gene id: 8090:foxf1
uniprot id: A0A3P9H6S8
uniprot id: H2M0F1
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101158642
gene id: 8090:LOC101158642
uniprot id: H2LQL6
names: Subcellular Location Annotation
messages: Membrane

8090:etnppl
gene id: 8090:etnppl
uniprot id: H2LJK7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

8090:LOC101157161
gene id: 8090:LOC101157161
uniprot id: A0A3P9LU91
uniprot id: H2LVB3
names: Similarity
messages: Belongs to the actin family.

8090:LOC101158704
gene id: 8090:LOC101158704
uniprot id: H2MAA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

8090:LOC101161312
gene id: 8090:LOC101161312
uniprot id: H2MQN2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:aldoc
gene id: 8090:aldoc
uniprot id: A0A3B3I8F0
uniprot id: A0A3P9M2F7
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

8090:foxe1
gene id: 8090:foxe1
uniprot id: C1K2Z0
names: Subcellular Location Annotation
messages: Nucleus

8090:pcsk7
gene id: 8090:pcsk7
uniprot id: A0A3P9K9Z0
uniprot id: H2MLV3
names: Similarity
messages: Belongs to the peptidase S8 family.

8090:LOC101154762
gene id: 8090:LOC101154762
uniprot id: H2L6H4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8090:LOC101175431
gene id: 8090:LOC101175431
uniprot id: H2LQ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

8090:mrpl35
gene id: 8090:mrpl35
uniprot id: H2MMI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

8090:zic4
gene id: 8090:zic4
uniprot id: A0A3P9J9X2
uniprot id: Q7T1Q8
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8090:LOC101170792
gene id: 8090:LOC101170792
uniprot id: A0A3P9MH59
uniprot id: H2MJD2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:mlec
gene id: 8090:mlec
uniprot id: A0A3P9JDK4
uniprot id: H2MI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:bop1
gene id: 8090:bop1
uniprot id: H2L8A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

8090:LOC101155726
gene id: 8090:LOC101155726
uniprot id: A0A3P9I453
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8090:LOC101162955
gene id: 8090:LOC101162955
uniprot id: A0A3P9HPD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

8090:LOC101170450
gene id: 8090:LOC101170450
uniprot id: A0A3B3HP16
uniprot id: H2L5H0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8090:rgma
gene id: 8090:rgma
uniprot id: H2LWS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

8090:pnpt1
gene id: 8090:pnpt1
uniprot id: H2LHG8
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

8090:LOC101158175
gene id: 8090:LOC101158175
uniprot id: A0A3B3HT08
uniprot id: A0A3P9LKD3
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

8090:rxra
gene id: 8090:rxra
uniprot id: A0A3B3HXZ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

8090:prox1
gene id: 8090:prox1
uniprot id: A0A3P9KJF7
uniprot id: C4TJE0
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101174042
gene id: 8090:LOC101174042
uniprot id: A0A3B3HEZ8
uniprot id: A0A3P9JGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8090:abcc5
gene id: 8090:abcc5
uniprot id: H2L592
names: Subcellular Location Annotation
messages: Membrane

8090:mrps25
gene id: 8090:mrps25
uniprot id: H2M5D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

8090:sfxn1
gene id: 8090:sfxn1
uniprot id: A0A3B3HWC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

8090:tmod4
gene id: 8090:tmod4
uniprot id: H2MM60
names: Subcellular Location Annotation
messages: cytoskeleton

8090:elavl3
gene id: 8090:elavl3
uniprot id: A0A3P9K5P9
names: Similarity
messages: Belongs to the RRM elav family.

8090:ostc
gene id: 8090:ostc
uniprot id: A0A3P9HTK9
uniprot id: H2LJH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8090:man1b1
gene id: 8090:man1b1
uniprot id: H2MTU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

8090:l1cam
gene id: 8090:l1cam
uniprot id: A0A3B3H266
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

8090:rec8
gene id: 8090:rec8
uniprot id: A0A3B3I174
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101165274
gene id: 8090:LOC101165274
uniprot id: H2M444
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:sec61b
gene id: 8090:sec61b
uniprot id: A0A3B3I1G3
uniprot id: A0A3P9JNG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

8090:LOC105354868
gene id: 8090:LOC105354868
uniprot id: A0A3B3I0T1
names: Similarity
messages: Belongs to the dapper family.

8090:gusb
gene id: 8090:gusb
uniprot id: H2M6N1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homotetramer.
messages: Inhibited by L-aspartic acid.
messages: Lysosome
messages: Plays an important role in the degradation of dermatan and keratan sulfates.

8090:LOC101169019
gene id: 8090:LOC101169019
uniprot id: A0A3B3INW6
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101164071
gene id: 8090:LOC101164071
uniprot id: H2LP50
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

8090:nbn
gene id: 8090:nbn
uniprot id: H2M0B9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

8090:stxbp3
gene id: 8090:stxbp3
uniprot id: H2M7G6
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8090:hdhd3
gene id: 8090:hdhd3
uniprot id: A0A3B3HPL0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

8090:tas1r2a
gene id: 8090:tas1r2a
uniprot id: Q2MHK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:ppp2cb
gene id: 8090:ppp2cb
uniprot id: A0A3B3H7N1
uniprot id: A0A3P9HFS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8090:LOC101171679
gene id: 8090:LOC101171679
uniprot id: A0A3B3I8C1
names: Subcellular Location Annotation
messages: Membrane

8090:fgf20b
gene id: 8090:fgf20b
uniprot id: Q0KJ02
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8090:sap18
gene id: 8090:sap18
uniprot id: A0A3B3HQN3
uniprot id: A0A3P9IAY8
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

8090:LOC101171813
gene id: 8090:LOC101171813
uniprot id: A0A3B3I0J8
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

8090:sema3g
gene id: 8090:sema3g
uniprot id: H2LDY0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:copg2
gene id: 8090:copg2
uniprot id: A0A3P9MCL0
uniprot id: H2MHZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

8090:LOC101169671
gene id: 8090:LOC101169671
uniprot id: H2N171
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

8090:wnt3
gene id: 8090:wnt3
uniprot id: A0A3P9IK85
uniprot id: H2M976
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8090:degs1
gene id: 8090:degs1
uniprot id: A0A3P9HXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:slc26a5
gene id: 8090:slc26a5
uniprot id: H2MW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

8090:supt4h1
gene id: 8090:supt4h1
uniprot id: A0A3P9H0E9
uniprot id: H2M633
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

8090:mlf2
gene id: 8090:mlf2
uniprot id: H2MAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

8090:LOC101170313
gene id: 8090:LOC101170313
uniprot id: A0A3P9I7L1
uniprot id: H2MAL4
names: Similarity
messages: Belongs to the RRM elav family.

8090:fam135b
gene id: 8090:fam135b
uniprot id: H2ME42
names: Similarity
messages: Belongs to the FAM135 family.

8090:gnpnat1
gene id: 8090:gnpnat1
uniprot id: A0A3P9JZV1
uniprot id: H2M8S3
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

8090:pisd
gene id: 8090:pisd
uniprot id: H2MZC2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

8090:erbb3
gene id: 8090:erbb3
uniprot id: H2L7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

8090:LOC101172228
gene id: 8090:LOC101172228
uniprot id: H2N129
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

8090:prmt7
gene id: 8090:prmt7
uniprot id: H2MJK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

8090:immp2l
gene id: 8090:immp2l
uniprot id: H2L5C6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

8090:tshr
gene id: 8090:tshr
uniprot id: H2M4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

8090:aldh6a1
gene id: 8090:aldh6a1
uniprot id: H2MNV8
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

8090:b4galt1
gene id: 8090:b4galt1
uniprot id: A0A3B3HLX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

8090:slc39a3
gene id: 8090:slc39a3
uniprot id: H2LAI2
names: Subcellular Location Annotation
messages: Membrane

8090:LOC100049480
gene id: 8090:LOC100049480
uniprot id: H2L975
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

8090:olgc9
gene id: 8090:olgc9
uniprot id: Q75Q01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

8090:KEF90 p03
gene id: 8090:KEF90_p03
uniprot id: Q8HLW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

8090:eif2d
gene id: 8090:eif2d
uniprot id: H2M3Y9
names: Similarity
messages: Belongs to the eIF2D family.

8090:LOC101173137
gene id: 8090:LOC101173137
uniprot id: H2MNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

8090:yars2
gene id: 8090:yars2
uniprot id: H2LAU5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

8090:LOC101161735
gene id: 8090:LOC101161735
uniprot id: H2M2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

8090:scpep1
gene id: 8090:scpep1
uniprot id: H2MS65
names: Similarity
messages: Belongs to the peptidase S10 family.

8090:LOC101155030
gene id: 8090:LOC101155030
uniprot id: Q78DI0
uniprot id: Q9PVU6
names: Function
names: Similarity
names: Subunit
names: Tissue Specificity
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from gills to the various peripheral tissues.
messages: Red blood cells.

8090:dbx2
gene id: 8090:dbx2
uniprot id: A0A3B3IIB3
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101165676
gene id: 8090:LOC101165676
uniprot id: A0A3B3HF27
names: Subcellular Location Annotation
messages: Secreted

8090:kif5b
gene id: 8090:kif5b
uniprot id: H2LHI1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:LOC101158196
gene id: 8090:LOC101158196
uniprot id: H2LJ62
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101166566
gene id: 8090:LOC101166566
uniprot id: H2L691
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8090:crkl
gene id: 8090:crkl
uniprot id: H2M629
names: Similarity
messages: Belongs to the CRK family.

8090:LOC101161258
gene id: 8090:LOC101161258
uniprot id: H2LB46
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

8090:picalm
gene id: 8090:picalm
uniprot id: A0A3B3H6K9
uniprot id: A0A3B3H9V3
uniprot id: A0A3B3I218
uniprot id: A0A3B3I9F5
uniprot id: A0A3B3IEG8
uniprot id: A0A3P9HUC0
uniprot id: A0A3P9HUC7
uniprot id: A0A3P9HUF9
uniprot id: A0A3P9JA02
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

8090:foxa2
gene id: 8090:foxa2
uniprot id: O42097
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription activator for a number of liver genes. Interacts with the cis-acting regulatory regions of these genes (By similarity).

8090:LOC101155699
gene id: 8090:LOC101155699
uniprot id: A0A3P9KYZ8
uniprot id: H2L4G3
names: Similarity
messages: Belongs to the S-100 family.

8090:LOC101161218
gene id: 8090:LOC101161218
uniprot id: H2LXI5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101164479
gene id: 8090:LOC101164479
uniprot id: H2MDH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8090:LOC101167793
gene id: 8090:LOC101167793
uniprot id: A0A3B3HGP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

8090:wisp3
gene id: 8090:wisp3
uniprot id: H2MUT9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101173163
gene id: 8090:LOC101173163
uniprot id: A0A3B3H322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:gab3
gene id: 8090:gab3
uniprot id: H2M0U2
names: Similarity
messages: Belongs to the GAB family.

8090:c8b
gene id: 8090:c8b
uniprot id: H2M1Q0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101175168
gene id: 8090:LOC101175168
uniprot id: H2LXA5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

8090:yeats4
gene id: 8090:yeats4
uniprot id: A0A3P9JG98
uniprot id: H2MFM7
names: Subcellular Location Annotation
messages: Nucleus

8090:mag
gene id: 8090:mag
uniprot id: H2MKD5
names: Subcellular Location Annotation
messages: Membrane

8090:irx6
gene id: 8090:irx6
uniprot id: A0A3B3I3N9
names: Subcellular Location Annotation
messages: Nucleus

8090:ssbp2
gene id: 8090:ssbp2
uniprot id: A0A3B3HW53
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101172757
gene id: 8090:LOC101172757
uniprot id: A0A3B3I4V5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

8090:rrp12
gene id: 8090:rrp12
uniprot id: H2LXP6
names: Similarity
messages: Belongs to the RRP12 family.

8090:tgfb3
gene id: 8090:tgfb3
uniprot id: A0A3P9IYP0
uniprot id: H2MPS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

8090:sars2
gene id: 8090:sars2
uniprot id: H2LXU3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

8090:fzd4
gene id: 8090:fzd4
uniprot id: H2M4Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

8090:LOC101157543
gene id: 8090:LOC101157543
uniprot id: H2M0C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

8090:rpl7
gene id: 8090:rpl7
uniprot id: A0A3P9L4C3
uniprot id: Q45RI2
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

8090:LOC101165241
gene id: 8090:LOC101165241
uniprot id: H2L7V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

8090:LOC101158550
gene id: 8090:LOC101158550
uniprot id: H2M2W5
names: Similarity
messages: Belongs to the nucleoplasmin family.

8090:dpm1
gene id: 8090:dpm1
uniprot id: A0A3P9LHR4
uniprot id: H2L910
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex.

8090:LOC101172725
gene id: 8090:LOC101172725
uniprot id: A0A3P9JQ79
uniprot id: H2MH04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8090:mad1l1
gene id: 8090:mad1l1
uniprot id: A0A3B3IJ39
names: Similarity
messages: Belongs to the MAD1 family.

8090:tcf25
gene id: 8090:tcf25
uniprot id: H2M050
names: Similarity
messages: Belongs to the TCF25 family.

8090:setd6
gene id: 8090:setd6
uniprot id: H2MJ57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

8090:slc29a1
gene id: 8090:slc29a1
uniprot id: A0A3B3I601
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

8090:mtnr1a
gene id: 8090:mtnr1a
uniprot id: H2LVT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

8090:sema3e
gene id: 8090:sema3e
uniprot id: H2M0K0
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:ric8b
gene id: 8090:ric8b
uniprot id: H2M6B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

8090:LOC101169036
gene id: 8090:LOC101169036
uniprot id: H2L8J3
names: Similarity
messages: Belongs to the nucleobindin family.

8090:LOC101174308
gene id: 8090:LOC101174308
uniprot id: A0A3B3H661
uniprot id: A0A3B3HFF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

8090:kif7
gene id: 8090:kif7
uniprot id: A0A3B3IB15
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:LOC101175061
gene id: 8090:LOC101175061
uniprot id: H2LEW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

8090:LOC101159817
gene id: 8090:LOC101159817
uniprot id: H2MMM3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

8090:lsm5
gene id: 8090:lsm5
uniprot id: A0A3P9ITZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

8090:pomt1
gene id: 8090:pomt1
uniprot id: H2MPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

8090:LOC101165005
gene id: 8090:LOC101165005
uniprot id: H2MRM5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

8090:LOC101168330
gene id: 8090:LOC101168330
uniprot id: A0A3P9K4Y3
uniprot id: H2MBS8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:LOC101167121
gene id: 8090:LOC101167121
uniprot id: H2LSV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

8090:gabra1
gene id: 8090:gabra1
uniprot id: A0A3B3III2
uniprot id: A0A3P9LGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC105356917
gene id: 8090:LOC105356917
uniprot id: A0A3B3IK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

8090:LOC101162623
gene id: 8090:LOC101162623
uniprot id: H2M0G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:LOC101162283
gene id: 8090:LOC101162283
uniprot id: H2LUT9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

8090:LOC101158863
gene id: 8090:LOC101158863
uniprot id: A0A3B3IGF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

8090:LOC101167963
gene id: 8090:LOC101167963
uniprot id: H2LDF2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

8090:LOC101168358
gene id: 8090:LOC101168358
uniprot id: H2L5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

8090:rp2
gene id: 8090:rp2
uniprot id: H2MMY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

8090:LOC101157328
gene id: 8090:LOC101157328
uniprot id: H2LNR6
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

8090:LOC101163081
gene id: 8090:LOC101163081
uniprot id: A0A3B3IJF1
uniprot id: A0A3P9M8U0
names: Subcellular Location Annotation
messages: Membrane

8090:gtf2a2
gene id: 8090:gtf2a2
uniprot id: A0A3P9JBY1
uniprot id: H2MVY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

8090:rps16
gene id: 8090:rps16
uniprot id: A0A3P9HIS5
uniprot id: H2MNR1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

8090:ctsc
gene id: 8090:ctsc
uniprot id: A0A3B3HM18
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

8090:crot
gene id: 8090:crot
uniprot id: H2LZN7
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

8090:LOC101169699
gene id: 8090:LOC101169699
uniprot id: H2MGR5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

8090:LOC101155297
gene id: 8090:LOC101155297
uniprot id: H2ME76
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:LOC101163295
gene id: 8090:LOC101163295
uniprot id: H2MXJ1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC101160764
gene id: 8090:LOC101160764
uniprot id: A0A3B3IPI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

8090:LOC101173145
gene id: 8090:LOC101173145
uniprot id: H2MI34
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8090:dpys
gene id: 8090:dpys
uniprot id: A0A3B3HSV0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

8090:copa
gene id: 8090:copa
uniprot id: H2LCD8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

8090:LOC100049338
gene id: 8090:LOC100049338
uniprot id: A0A3P9KFX4
uniprot id: Q9W7D6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

8090:ddx52
gene id: 8090:ddx52
uniprot id: A0A3B3H569
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8090:bgn
gene id: 8090:bgn
uniprot id: A0A3P9K549
uniprot id: H2LXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

8090:rgs7bp
gene id: 8090:rgs7bp
uniprot id: A0A3B3HL07
uniprot id: A0A3P9HPY0
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

8090:LOC101167709
gene id: 8090:LOC101167709
uniprot id: H2MF48
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101175176
gene id: 8090:LOC101175176
uniprot id: H2M160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

8090:vcl
gene id: 8090:vcl
uniprot id: H2LX47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: podosome

8090:nr5a2
gene id: 8090:nr5a2
uniprot id: Q2QCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

8090:LOC101170261
gene id: 8090:LOC101170261
uniprot id: H2MID6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

8090:LOC101168460
gene id: 8090:LOC101168460
uniprot id: A0A3B3I4Q1
names: Subcellular Location Annotation
messages: Membrane

8090:comt
gene id: 8090:comt
uniprot id: H2MGV3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

8090:LOC101160561
gene id: 8090:LOC101160561
uniprot id: A0A3B3HMI8
uniprot id: A0A3P9I8W1
names: Similarity
messages: Belongs to the importin alpha family.

8090:msrb2
gene id: 8090:msrb2
uniprot id: H2LSB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

8090:LOC101172833
gene id: 8090:LOC101172833
uniprot id: A0A3B3HLQ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101157767
gene id: 8090:LOC101157767
uniprot id: H2MJH1
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:dlk1
gene id: 8090:dlk1
uniprot id: A0A3B3ID50
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101175473
gene id: 8090:LOC101175473
uniprot id: A0A3B3H7Z2
names: Subcellular Location Annotation
messages: Membrane

8090:vps11
gene id: 8090:vps11
uniprot id: Q0PN15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS11 family.
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: autophagosome
messages: clathrin-coated vesicle

8090:usp45
gene id: 8090:usp45
uniprot id: H2L9Z9
names: Similarity
messages: Belongs to the peptidase C19 family.

8090:LOC101172157
gene id: 8090:LOC101172157
uniprot id: A0A3B3HBV1
uniprot id: A0A3P9HZP1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:dmrta1
gene id: 8090:dmrta1
uniprot id: H2LGU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

8090:ctu1
gene id: 8090:ctu1
uniprot id: H2MIW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

8090:LOC101172410
gene id: 8090:LOC101172410
uniprot id: H2M6R4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8090:LOC101164252
gene id: 8090:LOC101164252
uniprot id: A0A3B3H4I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

8090:LOC101162633
gene id: 8090:LOC101162633
uniprot id: A0A3B3INF7
uniprot id: A0A3P9MIP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

8090:LOC101165416
gene id: 8090:LOC101165416
uniprot id: H2LQJ5
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

8090:mmp19
gene id: 8090:mmp19
uniprot id: H2MJT7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:sf3a3
gene id: 8090:sf3a3
uniprot id: H2LVY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3A3 family.
messages: Nucleus

8090:LOC101163636
gene id: 8090:LOC101163636
uniprot id: H2LKG8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

8090:LOC101166166
gene id: 8090:LOC101166166
uniprot id: A0A3B3I4B8
names: Subcellular Location Annotation
messages: Membrane

8090:alg9
gene id: 8090:alg9
uniprot id: H2LMS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:rffl
gene id: 8090:rffl
uniprot id: A0A3B3IHR8
names: Subcellular Location Annotation
messages: Cell membrane

8090:mtx2
gene id: 8090:mtx2
uniprot id: A0A3P9K2F7
uniprot id: H2L742
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

8090:LOC101164208
gene id: 8090:LOC101164208
uniprot id: H2L3V1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8090:LOC101159650
gene id: 8090:LOC101159650
uniprot id: A0A3P9HKW9
uniprot id: H2MW25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

8090:fam212b
gene id: 8090:fam212b
uniprot id: A0A3B3I4Q8
uniprot id: A0A3P9JAT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

8090:LOC101173361
gene id: 8090:LOC101173361
uniprot id: H2MZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8090:LOC101158985
gene id: 8090:LOC101158985
uniprot id: A0A3P9MBU6
uniprot id: H2MFV2
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101167630
gene id: 8090:LOC101167630
uniprot id: H2M3U5
names: Similarity
messages: Belongs to the heme oxygenase family.

8090:rprd1a
gene id: 8090:rprd1a
uniprot id: H2M8V9
names: Similarity
messages: Belongs to the UPF0400 (RTT103) family.

8090:LOC101160155
gene id: 8090:LOC101160155
uniprot id: H2LTW6
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101161073
gene id: 8090:LOC101161073
uniprot id: A0A3B3HFZ1
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

8090:mmp2
gene id: 8090:mmp2
uniprot id: Q9PTU7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

8090:hmx3
gene id: 8090:hmx3
uniprot id: H2M0P6
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101168689
gene id: 8090:LOC101168689
uniprot id: A0A3P9KHT0
uniprot id: H2MYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8090:fstl4
gene id: 8090:fstl4
uniprot id: H2L618
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101172830
gene id: 8090:LOC101172830
uniprot id: Q3V634
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8090:LOC101157888
gene id: 8090:LOC101157888
uniprot id: H2MMW2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

8090:pabpc4
gene id: 8090:pabpc4
uniprot id: H2MSW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

8090:LOC101172748
gene id: 8090:LOC101172748
uniprot id: A0A3P9KBR8
uniprot id: H2MCV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

8090:sez6
gene id: 8090:sez6
uniprot id: H2M1T7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101163116
gene id: 8090:LOC101163116
uniprot id: A0A3B3IHI7
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:atg9a
gene id: 8090:atg9a
uniprot id: H2MEV3
uniprot id: Q3T8Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

8090:LOC101168234
gene id: 8090:LOC101168234
uniprot id: H2M0N2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:c17h1orf123
gene id: 8090:c17h1orf123
uniprot id: H2M3V9
names: Similarity
messages: Belongs to the UPF0587 family.

8090:spcs3
gene id: 8090:spcs3
uniprot id: A0A3B3H8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:fut9a
gene id: 8090:fut9a
uniprot id: A0A3P9MG02
uniprot id: Q5F2N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8090:mrpl28
gene id: 8090:mrpl28
uniprot id: A0A3P9LPN5
uniprot id: H2LR52
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

8090:c9
gene id: 8090:c9
uniprot id: H2LCR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:dhrs13
gene id: 8090:dhrs13
uniprot id: H2MF00
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:LOC101160265
gene id: 8090:LOC101160265
uniprot id: H2M891
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

8090:LOC101159094
gene id: 8090:LOC101159094
uniprot id: A0A3B3HEN4
names: Subcellular Location Annotation
messages: Nucleus

8090:chd1
gene id: 8090:chd1
uniprot id: H2MI02
names: Subcellular Location Annotation
messages: Nucleus

8090:wnt5b
gene id: 8090:wnt5b
uniprot id: A0A3B3HNW9
uniprot id: A0A3F2YNW0
uniprot id: O42122
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).
messages: Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
messages: extracellular matrix

8090:atp6v0a2
gene id: 8090:atp6v0a2
uniprot id: H2LR05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

8090:LOC101161831
gene id: 8090:LOC101161831
uniprot id: A0A3B3IN26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

8090:gmppa
gene id: 8090:gmppa
uniprot id: H2N1V2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

8090:LOC101160486
gene id: 8090:LOC101160486
uniprot id: H2L7Q8
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101163821
gene id: 8090:LOC101163821
uniprot id: A0A3B3HVB9
names: Similarity
messages: Belongs to the folate receptor family.

8090:LOC101161830
gene id: 8090:LOC101161830
uniprot id: A0A3B3I262
names: Subcellular Location Annotation
messages: Membrane

8090:edar
gene id: 8090:edar
uniprot id: Q90VY2
names: Developmental Stage
names: Function
names: Subcellular Location Annotation
messages: Barely detectable on the body surface of 8 and 15 day old fish. In 30 day old fish, when scale development has started, expression is high in patches of epithelial cell clusters and at the posterior margins of growing scales.
messages: Membrane
messages: Receptor for EDA (By similarity). May mediate the activation of NF-kappa-B and JNK.

8090:LOC101171493
gene id: 8090:LOC101171493
uniprot id: H2M3T6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:cpxm2
gene id: 8090:cpxm2
uniprot id: A0A3B3IIC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

8090:upf3b
gene id: 8090:upf3b
uniprot id: H2L623
names: Similarity
messages: Belongs to the RENT3 family.

8090:atp5mf
gene id: 8090:atp5mf
uniprot id: A0A3P9KGN6
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

8090:LOC101167075
gene id: 8090:LOC101167075
uniprot id: H2MUI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

8090:trappc3
gene id: 8090:trappc3
uniprot id: A0A3B3IL04
uniprot id: A0A3P9K6I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

8090:LOC101170044
gene id: 8090:LOC101170044
uniprot id: A0A3B3I7S7
uniprot id: H2LBS0
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

8090:LOC101168721
gene id: 8090:LOC101168721
uniprot id: A0A3P9L6Q5
uniprot id: H2M2P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

8090:bpgm
gene id: 8090:bpgm
uniprot id: A0A3P9J3J2
uniprot id: H2LF38
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

8090:cnp-3
gene id: 8090:cnp-3
uniprot id: Q4ADV1
uniprot id: Q800I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted
messages: Spinal cord, kidney, ovary, heart and spleen, and to a lower extent in brain and liver.

8090:LOC101170402
gene id: 8090:LOC101170402
uniprot id: H2M0Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

8090:rer1
gene id: 8090:rer1
uniprot id: A0A3P9HEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

8090:LOC101154948
gene id: 8090:LOC101154948
uniprot id: A0A3B3HYJ6
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8090:ewsr1
gene id: 8090:ewsr1
uniprot id: H2LQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

8090:unkl
gene id: 8090:unkl
uniprot id: H2LK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

8090:pcbd2
gene id: 8090:pcbd2
uniprot id: A0A3B3HM14
uniprot id: A0A3P9HFK4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

8090:LOC101174771
gene id: 8090:LOC101174771
uniprot id: A0A3B3HPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

8090:dct
gene id: 8090:dct
uniprot id: H2MTX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

8090:psmb9
gene id: 8090:psmb9
uniprot id: Q589Q5
uniprot id: Q8UW64
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autocleaved. The resulting N-terminal Thr residue of the mature subunit is responsible for the nucleophile proteolytic activity.
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. Component of the immunoproteasome, where it displaces the equivalent housekeeping subunit PSMB6 (By similarity).
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides (By similarity).
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

8090:LOC101168723
gene id: 8090:LOC101168723
uniprot id: A0A3B3I5J2
uniprot id: A0A3P9JSI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

8090:polr1b
gene id: 8090:polr1b
uniprot id: H2L5L1
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

8090:LOC101166969
gene id: 8090:LOC101166969
uniprot id: A0A3P9LHN4
uniprot id: H2L883
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

8090:smg8
gene id: 8090:smg8
uniprot id: H2MGV8
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

8090:kdsr
gene id: 8090:kdsr
uniprot id: A0A3P9KR20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:sord
gene id: 8090:sord
uniprot id: H2LPQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Mitochondrion membrane
messages: flagellum

8090:LOC101157923
gene id: 8090:LOC101157923
uniprot id: H2LA78
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:LOC101162958
gene id: 8090:LOC101162958
uniprot id: A0A3B3HD89
uniprot id: A0A3B3I1R4
uniprot id: H2MTV7
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

8090:gata2
gene id: 8090:gata2
uniprot id: Q5KST7
names: Subcellular Location Annotation
messages: Nucleus

8090:rln3
gene id: 8090:rln3
uniprot id: Q0Q7C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

8090:LOC101164256
gene id: 8090:LOC101164256
uniprot id: H2LRA9
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

8090:LOC101168449
gene id: 8090:LOC101168449
uniprot id: A0A3B3IPN1
names: Subcellular Location Annotation
messages: centrosome
messages: perinuclear region

8090:ncoa2
gene id: 8090:ncoa2
uniprot id: H2LVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

8090:cnih1
gene id: 8090:cnih1
uniprot id: A0A3P9IPB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

8090:acsl4
gene id: 8090:acsl4
uniprot id: H2LVF5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

8090:neil3
gene id: 8090:neil3
uniprot id: H2N1D7
names: Similarity
messages: Belongs to the FPG family.

8090:megf6
gene id: 8090:megf6
uniprot id: H2LHK3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101166011
gene id: 8090:LOC101166011
uniprot id: H2MBI2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:snrpg
gene id: 8090:snrpg
uniprot id: A0A3B3HZG8
uniprot id: A0A3P9I2H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

8090:LOC101170875
gene id: 8090:LOC101170875
uniprot id: A0A3B3HZH4
names: Similarity
messages: Belongs to the cullin family.

8090:LOC101164181
gene id: 8090:LOC101164181
uniprot id: A0A3B3HJ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

8090:LOC101173653
gene id: 8090:LOC101173653
uniprot id: A0A3B3IBQ8
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101163128
gene id: 8090:LOC101163128
uniprot id: H2MBR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

8090:foxi3
gene id: 8090:foxi3
uniprot id: C1K2Z7
names: Subcellular Location Annotation
messages: Nucleus

8090:txnl4a
gene id: 8090:txnl4a
uniprot id: A0A3B3HCV1
uniprot id: A0A3P9K893
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

8090:rnf13
gene id: 8090:rnf13
uniprot id: H2LT22
names: Subcellular Location Annotation
messages: Membrane

8090:uckl1
gene id: 8090:uckl1
uniprot id: A0A3B3HWV8
uniprot id: A0A3P9JLU5
uniprot id: A0A3P9JX01
uniprot id: H2M150
uniprot id: H2M152
names: Similarity
messages: Belongs to the uridine kinase family.

8090:LOC101169307
gene id: 8090:LOC101169307
uniprot id: A0A3B3HKL8
names: Similarity
messages: Belongs to the angiomotin family.

8090:pipox
gene id: 8090:pipox
uniprot id: H2MF46
names: Similarity
messages: Belongs to the MSOX/MTOX family.

8090:LOC101170383
gene id: 8090:LOC101170383
uniprot id: H2MHM9
names: Similarity
messages: Belongs to the RCAN family.

8090:LOC101166354
gene id: 8090:LOC101166354
uniprot id: A0A3B3HHT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

8090:arsa
gene id: 8090:arsa
uniprot id: H2M2A6
names: Similarity
messages: Belongs to the sulfatase family.

8090:slc30a4
gene id: 8090:slc30a4
uniprot id: H2LAZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8090:LOC101175170
gene id: 8090:LOC101175170
uniprot id: A0A3B3H6I4
uniprot id: A0A3B3H7W6
uniprot id: A0A3P9HHU9
uniprot id: A0A3P9HHV7
uniprot id: A0A3P9MJ52
uniprot id: H2MPE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

8090:ezh2
gene id: 8090:ezh2
uniprot id: Q5TKR5
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101165167
gene id: 8090:LOC101165167
uniprot id: H2LE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

8090:LOC101156743
gene id: 8090:LOC101156743
uniprot id: H2LCH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

8090:tango6
gene id: 8090:tango6
uniprot id: H2MIW5
names: Similarity
messages: Belongs to the Tango6 family.

8090:KEF90 p09
gene id: 8090:KEF90_p09
uniprot id: Q8HLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrion membrane

8090:pde7b
gene id: 8090:pde7b
uniprot id: H2MPU9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8090:map3k7
gene id: 8090:map3k7
uniprot id: A0A3B3H678
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

8090:tm2d3
gene id: 8090:tm2d3
uniprot id: H2MGZ0
names: Subcellular Location Annotation
messages: Membrane

8090:ppara
gene id: 8090:ppara
uniprot id: A0A3P9JYD4
uniprot id: C4B6E0
uniprot id: H2M628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8090:slc35c1
gene id: 8090:slc35c1
uniprot id: A0A3B3I054
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101173640
gene id: 8090:LOC101173640
uniprot id: H2LNN0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

8090:ehf
gene id: 8090:ehf
uniprot id: A0A3B3HB43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

8090:LOC101167472
gene id: 8090:LOC101167472
uniprot id: H2LVZ3
names: Similarity
messages: Belongs to the CNKSR family.

8090:bag6
gene id: 8090:bag6
uniprot id: H2MN12
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol
messages: extracellular exosome

8090:LOC101156096
gene id: 8090:LOC101156096
uniprot id: A0A3B3INN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:elavl2
gene id: 8090:elavl2
uniprot id: A0A3P9L2T1
uniprot id: H2LH30
names: Similarity
messages: Belongs to the RRM elav family.

8090:fut7
gene id: 8090:fut7
uniprot id: Q5F2P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8090:LOC101157089
gene id: 8090:LOC101157089
uniprot id: A0A3B3HUM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

8090:LOC101172913
gene id: 8090:LOC101172913
uniprot id: H2MGL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins.
messages: Nucleus

8090:LOC101174131
gene id: 8090:LOC101174131
uniprot id: A0A3B3IP93
names: Similarity
messages: Belongs to the intermediate filament family.

8090:nsun4
gene id: 8090:nsun4
uniprot id: H2LX75
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

8090:ublcp1
gene id: 8090:ublcp1
uniprot id: A0A3B3IJ89
uniprot id: A0A3P9L8B2
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC100125487
gene id: 8090:LOC100125487
uniprot id: H2L7Q6
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

8090:LOC101157122
gene id: 8090:LOC101157122
uniprot id: A0A3P9H2P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

8090:gtf2h1
gene id: 8090:gtf2h1
uniprot id: H2LNK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

8090:neu3b
gene id: 8090:neu3b
uniprot id: G3XKV7
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

8090:LOC101166553
gene id: 8090:LOC101166553
uniprot id: A0A3P9IZA9
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

8090:pde11a
gene id: 8090:pde11a
uniprot id: A0A3B3IN27
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

8090:slc44a4
gene id: 8090:slc44a4
uniprot id: H2L941
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8090:LOC101161349
gene id: 8090:LOC101161349
uniprot id: H2LQY7
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101172860
gene id: 8090:LOC101172860
uniprot id: H2MRF9
names: Similarity
messages: Belongs to the globin family.

8090:leo1
gene id: 8090:leo1
uniprot id: H2LD28
names: Similarity
messages: Belongs to the LEO1 family.

8090:tmem35a
gene id: 8090:tmem35a
uniprot id: A0A3P9LJR5
uniprot id: H2L7F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

8090:LOC101169477
gene id: 8090:LOC101169477
uniprot id: A0A3B3HSM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

8090:gfra1
gene id: 8090:gfra1
uniprot id: H2LJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

8090:six6
gene id: 8090:six6
uniprot id: A0A3P9KKB4
uniprot id: H2MM07
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101168046
gene id: 8090:LOC101168046
uniprot id: A0A3B3IKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

8090:pdgfrl
gene id: 8090:pdgfrl
uniprot id: H2M2X7
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Membrane

8090:LOC101163681
gene id: 8090:LOC101163681
uniprot id: A0A3B3HD63
uniprot id: A0A3P9IZ34
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

8090:atg4d
gene id: 8090:atg4d
uniprot id: H2LGD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8090:LOC101157982
gene id: 8090:LOC101157982
uniprot id: H2MCV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

8090:LOC101160793
gene id: 8090:LOC101160793
uniprot id: H2L4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8090:prox1b
gene id: 8090:prox1b
uniprot id: C4TJE1
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101168609
gene id: 8090:LOC101168609
uniprot id: H2LMI4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:snrpd2
gene id: 8090:snrpd2
uniprot id: A0A3B3IJ97
uniprot id: A0A3P9KPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

8090:dcaf11
gene id: 8090:dcaf11
uniprot id: H2LP21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

8090:LOC101165680
gene id: 8090:LOC101165680
uniprot id: H2MF04
names: Similarity
messages: Belongs to the peptidase C48 family.

8090:ing4
gene id: 8090:ing4
uniprot id: A0A3P9K8B9
uniprot id: H2M9N9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

8090:parp6
gene id: 8090:parp6
uniprot id: A0A3P9JNZ9
uniprot id: H2MDU9
names: Similarity
messages: Belongs to the ARTD/PARP family.

8090:kcnk1
gene id: 8090:kcnk1
uniprot id: A0A3B3I167
uniprot id: A0A3P9LC74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

8090:LOC101166148
gene id: 8090:LOC101166148
uniprot id: A0A3B3HYN7
names: Similarity
messages: Belongs to the DEAD box helicase family.

8090:pparg
gene id: 8090:pparg
uniprot id: C4B6E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

8090:LOC101174910
gene id: 8090:LOC101174910
uniprot id: A0A3B3I2H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8090:LOC101165655
gene id: 8090:LOC101165655
uniprot id: A0A3B3I5B5
uniprot id: A0A3P9L7H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

8090:igdcc3
gene id: 8090:igdcc3
uniprot id: A0A3B3IGB0
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101164792
gene id: 8090:LOC101164792
uniprot id: A0A3P9IQN5
uniprot id: H2LFP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

8090:LOC101158370
gene id: 8090:LOC101158370
uniprot id: H2M6Z2
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101174621
gene id: 8090:LOC101174621
uniprot id: H2MLJ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:psmc3
gene id: 8090:psmc3
uniprot id: A0A3P9H0Y6
uniprot id: C0SQJ3
names: Similarity
messages: Belongs to the AAA ATPase family.

8090:glo1
gene id: 8090:glo1
uniprot id: A0A3P9I4I8
uniprot id: H2MIX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

8090:lhfpl6
gene id: 8090:lhfpl6
uniprot id: A0A3P9MC32
uniprot id: H2LCX8
names: Subcellular Location Annotation
messages: Membrane

8090:rpl21
gene id: 8090:rpl21
uniprot id: A0A3P9MB32
uniprot id: H2LY36
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

8090:LOC101174073
gene id: 8090:LOC101174073
uniprot id: A0A3B3HG10
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

8090:rh50
gene id: 8090:rh50
uniprot id: Q9DGD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

8090:LOC101160192
gene id: 8090:LOC101160192
uniprot id: A0A3P9KHT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

8090:imp3
gene id: 8090:imp3
uniprot id: A0A3P9K3D9
uniprot id: H2LI14
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

8090:LOC101166715
gene id: 8090:LOC101166715
uniprot id: A0A3B3HS90
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:slc46a1
gene id: 8090:slc46a1
uniprot id: H2LVP5
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101174425
gene id: 8090:LOC101174425
uniprot id: Q3V607
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8090:LOC101166621
gene id: 8090:LOC101166621
uniprot id: A0A3B3HQ42
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

8090:pkn1
gene id: 8090:pkn1
uniprot id: A0A3B3I8X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

8090:LOC101155457
gene id: 8090:LOC101155457
uniprot id: H2LRE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

8090:scfd1
gene id: 8090:scfd1
uniprot id: A0A3P9JWG0
uniprot id: H2M450
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

8090:LOC101174240
gene id: 8090:LOC101174240
uniprot id: H2MHC0
names: Subcellular Location Annotation
messages: Membrane

8090:isl1
gene id: 8090:isl1
uniprot id: N0D6U4
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101161069
gene id: 8090:LOC101161069
uniprot id: H2M4Y9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

8090:LOC101172525
gene id: 8090:LOC101172525
uniprot id: A0A3B3I668
uniprot id: A0A3P9IEK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8090:agk
gene id: 8090:agk
uniprot id: H2MMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

8090:LOC101173019
gene id: 8090:LOC101173019
uniprot id: H2LLS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: Secreted

8090:LOC101155523
gene id: 8090:LOC101155523
uniprot id: A0A3P9H8Q5
uniprot id: H2MSI7
names: Similarity
messages: Belongs to the actin family.

8090:LOC101170947
gene id: 8090:LOC101170947
uniprot id: H2LZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8090:LOC101172481
gene id: 8090:LOC101172481
uniprot id: H2L7Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:wnt9a
gene id: 8090:wnt9a
uniprot id: A0A3P9LZ80
uniprot id: H2MTC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8090:lyve1
gene id: 8090:lyve1
uniprot id: A0A3B3HFK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:dusp6
gene id: 8090:dusp6
uniprot id: H2MZX4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

8090:LOC101175525
gene id: 8090:LOC101175525
uniprot id: H2MJD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus
messages: ruffle membrane
messages: trans-Golgi network membrane

8090:LOC101172801
gene id: 8090:LOC101172801
uniprot id: H2LK03
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:rack1
gene id: 8090:rack1
uniprot id: A0A3B3HNS6
uniprot id: A0A3P9KSF3
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

8090:cpne3
gene id: 8090:cpne3
uniprot id: H2LK73
names: Similarity
messages: Belongs to the copine family.

8090:LOC101164558
gene id: 8090:LOC101164558
uniprot id: H2LNG0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:tmem234
gene id: 8090:tmem234
uniprot id: A0A3B3H8U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

8090:vldlr
gene id: 8090:vldlr
uniprot id: H2MJ58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:ltbp3
gene id: 8090:ltbp3
uniprot id: A0A3B3H8R9
uniprot id: A0A3B3HQR9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

8090:sbds
gene id: 8090:sbds
uniprot id: A0A3B3HXH0
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

8090:tube1
gene id: 8090:tube1
uniprot id: H2MUT2
names: Similarity
messages: Belongs to the tubulin family.

8090:wasf3
gene id: 8090:wasf3
uniprot id: H2LY90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

8090:mtrf1
gene id: 8090:mtrf1
uniprot id: H2LDK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

8090:arl1
gene id: 8090:arl1
uniprot id: A0A3P9LUD2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

8090:LOC101167980
gene id: 8090:LOC101167980
uniprot id: H2LXY1
names: Similarity
messages: Belongs to the TGF-beta family.

8090:LOC101159038
gene id: 8090:LOC101159038
uniprot id: H2MCU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

8090:LOC101157322
gene id: 8090:LOC101157322
uniprot id: H2LI59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8090:fgf10
gene id: 8090:fgf10
uniprot id: A0A3B3IA78
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8090:bsx
gene id: 8090:bsx
uniprot id: A0A3B3HB99
names: Subcellular Location Annotation
messages: Nucleus

8090:drd2
gene id: 8090:drd2
uniprot id: A0A3P9IUE4
uniprot id: H2LTK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:tmbim1
gene id: 8090:tmbim1
uniprot id: A0A3P9KIT6
uniprot id: H2M6K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

8090:LOC100301597
gene id: 8090:LOC100301597
uniprot id: A0A3B3INM0
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101174504
gene id: 8090:LOC101174504
uniprot id: H2LB28
names: Similarity
messages: Belongs to the RUNDC3 family.

8090:hars
gene id: 8090:hars
uniprot id: H2N252
uniprot id: H2N253
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

8090:LOC101160577
gene id: 8090:LOC101160577
uniprot id: H2ME20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

8090:csnk1a1
gene id: 8090:csnk1a1
uniprot id: A0A3P9KF16
uniprot id: A0A3P9KFA8
uniprot id: H2N284
uniprot id: H2N285
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:b3gat3
gene id: 8090:b3gat3
uniprot id: A0A3P9KRW4
uniprot id: H2LLX6
uniprot id: Q5CB06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:jam3
gene id: 8090:jam3
uniprot id: A0A3P9HW23
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101174467
gene id: 8090:LOC101174467
uniprot id: H2LMJ0
names: Similarity
messages: Belongs to the PAT1 family.

8090:stx7
gene id: 8090:stx7
uniprot id: A0A3B3H880
uniprot id: A0A3P9KY23
names: Similarity
messages: Belongs to the syntaxin family.

8090:LOC101174684
gene id: 8090:LOC101174684
uniprot id: H2LW99
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:fam241a
gene id: 8090:fam241a
uniprot id: A0A3B3HK18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

8090:adora2b
gene id: 8090:adora2b
uniprot id: H2M8V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101164106
gene id: 8090:LOC101164106
uniprot id: A0A3B3HY13
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

8090:rnf157
gene id: 8090:rnf157
uniprot id: A0A3B3HRI6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

8090:LOC101166237
gene id: 8090:LOC101166237
uniprot id: A0A3B3I8Q9
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101166586
gene id: 8090:LOC101166586
uniprot id: A0A3B3IFE3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:LOC101168231
gene id: 8090:LOC101168231
uniprot id: A0A3B3HRR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC101168958
gene id: 8090:LOC101168958
uniprot id: H2ME87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

8090:ints12
gene id: 8090:ints12
uniprot id: H2LQD2
names: Similarity
messages: Belongs to the Integrator subunit 12 family.

8090:vrtn
gene id: 8090:vrtn
uniprot id: H2MT81
names: Similarity
messages: Belongs to the vertnin family.

8090:arap3
gene id: 8090:arap3
uniprot id: H2N1R3
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC100533500
gene id: 8090:LOC100533500
uniprot id: E3WET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

8090:LOC101171699
gene id: 8090:LOC101171699
uniprot id: H2LSW0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

8090:LOC100049402
gene id: 8090:LOC100049402
uniprot id: Q6E211
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted
messages: Selectively regulates proliferation and morphogenesis of neural-crest derived pigment cells.

8090:ednr
gene id: 8090:ednr
uniprot id: Q9DEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:fan1
gene id: 8090:fan1
uniprot id: A0A3B3HSW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

8090:svbp
gene id: 8090:svbp
uniprot id: A0A3B3INY5
uniprot id: A0A3P9JZT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

8090:LOC101175530
gene id: 8090:LOC101175530
uniprot id: A0A3B3I296
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101154906
gene id: 8090:LOC101154906
uniprot id: H2LXI4
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

8090:atp5mg
gene id: 8090:atp5mg
uniprot id: A0A3P9L258
uniprot id: H2M9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

8090:u2af2
gene id: 8090:u2af2
uniprot id: A0A3P9HW71
uniprot id: H2M7K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

8090:usp48
gene id: 8090:usp48
uniprot id: H2M3E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

8090:tap1
gene id: 8090:tap1
uniprot id: H2MNB9
names: Subcellular Location Annotation
messages: Membrane

8090:vill
gene id: 8090:vill
uniprot id: A0A3B3I315
uniprot id: H2M0V4
names: Similarity
messages: Belongs to the villin/gelsolin family.

8090:chmp2a
gene id: 8090:chmp2a
uniprot id: A0A3P9MPU9
uniprot id: H2MAQ0
names: Similarity
messages: Belongs to the SNF7 family.

8090:hoxd3
gene id: 8090:hoxd3
uniprot id: A0A3P9LGY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8090:alkbh5
gene id: 8090:alkbh5
uniprot id: H2LZK7
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus speckle

8090:arhgef6
gene id: 8090:arhgef6
uniprot id: A0A3B3HMC5
uniprot id: H2L8I6
names: Subcellular Location Annotation
messages: lamellipodium

8090:rab21
gene id: 8090:rab21
uniprot id: A0A3B3HIZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: trans-Golgi network

8090:gad1
gene id: 8090:gad1
uniprot id: H2MS69
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

8090:mapk4
gene id: 8090:mapk4
uniprot id: A0A3B3HHK3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

8090:LOC101173766
gene id: 8090:LOC101173766
uniprot id: H2LEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

8090:lyrm4
gene id: 8090:lyrm4
uniprot id: A0A3B3IJ86
names: Similarity
messages: Belongs to the complex I LYR family.

8090:LOC101155802
gene id: 8090:LOC101155802
uniprot id: A0A3B3HUL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

8090:lpar4
gene id: 8090:lpar4
uniprot id: W8VX40
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:LOC101159435
gene id: 8090:LOC101159435
uniprot id: A0A3P9IPI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

8090:iah1
gene id: 8090:iah1
uniprot id: H2MKJ0
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

8090:eif4ebp1
gene id: 8090:eif4ebp1
uniprot id: A0A3P9L412
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8090:fzd6
gene id: 8090:fzd6
uniprot id: H2LAG8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101163073
gene id: 8090:LOC101163073
uniprot id: A0A3B3H572
names: Similarity
messages: Belongs to the PPP1R15 family.

8090:LOC101170997
gene id: 8090:LOC101170997
uniprot id: H2LFV5
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

8090:hsd17b10
gene id: 8090:hsd17b10
uniprot id: A0A3B3HLN0
uniprot id: A0A3P9IJ16
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:plcb2
gene id: 8090:plcb2
uniprot id: Q08JX0
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

8090:spdl1
gene id: 8090:spdl1
uniprot id: H2M552
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spindly family.
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex.
messages: kinetochore

8090:LOC101171555
gene id: 8090:LOC101171555
uniprot id: A0A3B3IBA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

8090:cilp
gene id: 8090:cilp
uniprot id: H2LP43
names: Subcellular Location Annotation
messages: Membrane
messages: extracellular matrix

8090:trappc2
gene id: 8090:trappc2
uniprot id: A0A3B3HR56
uniprot id: A0A3P9J9F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

8090:LOC101171075
gene id: 8090:LOC101171075
uniprot id: A0A3B3HIF7
uniprot id: A0A3P9KRL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

8090:tpt1
gene id: 8090:tpt1
uniprot id: A0A3P9H8Y8
uniprot id: C3V6N1
names: Similarity
messages: Belongs to the TCTP family.

8090:pgk1
gene id: 8090:pgk1
uniprot id: A0A3B3IJI0
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

8090:LOC101174301
gene id: 8090:LOC101174301
uniprot id: A0A3B3IDS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

8090:man2c1
gene id: 8090:man2c1
uniprot id: H2LSW4
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

8090:LOC101155341
gene id: 8090:LOC101155341
uniprot id: A0A3B3HW21
names: Similarity
messages: Belongs to the pyridoxine kinase family.

8090:tubd1
gene id: 8090:tubd1
uniprot id: H2MBE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

8090:LOC101161301
gene id: 8090:LOC101161301
uniprot id: H2LGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8090:msh2
gene id: 8090:msh2
uniprot id: H2M372
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

8090:LOC101169800
gene id: 8090:LOC101169800
uniprot id: H2LMY6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

8090:sec24c
gene id: 8090:sec24c
uniprot id: A0A3B3IBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

8090:LOC101175466
gene id: 8090:LOC101175466
uniprot id: H2N0M3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

8090:LOC101165497
gene id: 8090:LOC101165497
uniprot id: A0A3B3I4A7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:znf711
gene id: 8090:znf711
uniprot id: A0A3B3IJ71
names: Subcellular Location Annotation
messages: Nucleus

8090:tmtc3
gene id: 8090:tmtc3
uniprot id: A0A3B3HY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8090:skiv2l
gene id: 8090:skiv2l
uniprot id: H2L9I2
names: Subcellular Location Annotation
messages: Cytoplasm

8090:ddx1
gene id: 8090:ddx1
uniprot id: H2MQ88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule
messages: RNA helicase.
messages: The helicase domain is involved in the stimulation of RELA transcriptional activity.

8090:LOC101172178
gene id: 8090:LOC101172178
uniprot id: H2MG28
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:isca2
gene id: 8090:isca2
uniprot id: H2MP29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

8090:manba
gene id: 8090:manba
uniprot id: H2MVB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

8090:LOC101163647
gene id: 8090:LOC101163647
uniprot id: H2N2L6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101163260
gene id: 8090:LOC101163260
uniprot id: A0A3B3HR92
uniprot id: A0A3P9KA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

8090:ctgf
gene id: 8090:ctgf
uniprot id: H2MV06
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:nubp2
gene id: 8090:nubp2
uniprot id: H2LSJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

8090:LOC101163407
gene id: 8090:LOC101163407
uniprot id: H2LVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

8090:arl3
gene id: 8090:arl3
uniprot id: A0A3B3H597
uniprot id: A0A3P9LPN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

8090:eci1
gene id: 8090:eci1
uniprot id: H2MQ78
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8090:lhx5
gene id: 8090:lhx5
uniprot id: A0A3P9KXH4
uniprot id: H2L9K6
names: Subcellular Location Annotation
messages: Nucleus

8090:akt1
gene id: 8090:akt1
uniprot id: A0A3B3H2G6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8090:LOC101168572
gene id: 8090:LOC101168572
uniprot id: A0A3B3IH50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

8090:LOC101155538
gene id: 8090:LOC101155538
uniprot id: H2LG74
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:LOC101171134
gene id: 8090:LOC101171134
uniprot id: A0A3P9MNP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101166708
gene id: 8090:LOC101166708
uniprot id: H2LXP1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

8090:LOC101175377
gene id: 8090:LOC101175377
uniprot id: H2MII1
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

8090:hacd4
gene id: 8090:hacd4
uniprot id: A0A3P9KQ68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101167392
gene id: 8090:LOC101167392
uniprot id: A0A3B3HFH8
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101172155
gene id: 8090:LOC101172155
uniprot id: A0A3B3IMF5
uniprot id: A0A3P9HND7
names: Similarity
messages: Belongs to the TAFA family.

8090:mgst1
gene id: 8090:mgst1
uniprot id: A0A3B3HQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

8090:cnot8
gene id: 8090:cnot8
uniprot id: A0A3P9LXL4
uniprot id: H2MLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

8090:psmg2
gene id: 8090:psmg2
uniprot id: H2LCB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

8090:LOC101158110
gene id: 8090:LOC101158110
uniprot id: A0A3B3I982
names: Similarity
messages: Belongs to the peptidase M20A family.

8090:LOC101159741
gene id: 8090:LOC101159741
uniprot id: H2MM89
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

8090:ppp6r3
gene id: 8090:ppp6r3
uniprot id: A0A3B3HS36
uniprot id: A0A3B3HTV1
names: Similarity
messages: Belongs to the SAPS family.

8090:LOC101168223
gene id: 8090:LOC101168223
uniprot id: A0A3P9JUC1
uniprot id: Q8UUK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8090:LOC101166052
gene id: 8090:LOC101166052
uniprot id: A0A3B3HJG3
names: Similarity
messages: Belongs to the Rho GDI family.

8090:khdrbs3
gene id: 8090:khdrbs3
uniprot id: A0A3B3I774
uniprot id: A0A3P9MPV9
names: Similarity
messages: Belongs to the KHDRBS family.

8090:LOC101164408
gene id: 8090:LOC101164408
uniprot id: A0A3P9IDL8
uniprot id: H2LE91
names: Similarity
messages: Belongs to the syntaxin family.

8090:LOC101163689
gene id: 8090:LOC101163689
uniprot id: H2MQS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

8090:LOC100049265
gene id: 8090:LOC100049265
uniprot id: Q8JIS9
names: Similarity
messages: Belongs to the peptidase C14A family.

8090:ubl3
gene id: 8090:ubl3
uniprot id: A0A3B3HYG6
uniprot id: A0A3P9KZF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:notum
gene id: 8090:notum
uniprot id: A0A3P9LFJ4
uniprot id: H2LUM7
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

8090:LOC101173336
gene id: 8090:LOC101173336
uniprot id: H2MMS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8090:epha3
gene id: 8090:epha3
uniprot id: H2MMA8
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155451
gene id: 8090:LOC101155451
uniprot id: A0A3P9JHT7
uniprot id: H2MGP2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

8090:tp53rk
gene id: 8090:tp53rk
uniprot id: A0A3B3H5E4
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

8090:bcl2l13
gene id: 8090:bcl2l13
uniprot id: H2MMG3
names: Similarity
messages: Belongs to the Bcl-2 family.

8090:LOC101159369
gene id: 8090:LOC101159369
uniprot id: A0A3B3IFV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

8090:cfap298
gene id: 8090:cfap298
uniprot id: H2LHG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

8090:LOC101161472
gene id: 8090:LOC101161472
uniprot id: Q8JIR6
names: Developmental Stage
names: Disruption Phenotype
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the DMRT family.
messages: Expression starts at the neurula stage and persists during embryogenesis and larval stages until adulthood. At hatching and 5 days after hatching, present in XY embryos, but not in XX embryos. Detected only in the somatic cells surrounding germ cells in XY embryos.
messages: Feminization of XY offsprings.
messages: Nucleus
messages: Testis-specific. Localizes to Sertoli cells.
messages: Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and germ cell proliferation. Acts both as a transcription repressor and activator.

8090:pan3
gene id: 8090:pan3
uniprot id: H2LXY8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

8090:LOC101162605
gene id: 8090:LOC101162605
uniprot id: A0A3P9M4M6
uniprot id: H2L5B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

8090:LOC101165545
gene id: 8090:LOC101165545
uniprot id: A0A3P9JUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

8090:kif20a
gene id: 8090:kif20a
uniprot id: H2LQX5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:perp
gene id: 8090:perp
uniprot id: H2LJ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

8090:LOC101167823
gene id: 8090:LOC101167823
uniprot id: A0A3P9IQG3
uniprot id: H2MAS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

8090:LOC101163574
gene id: 8090:LOC101163574
uniprot id: H2L8M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.
messages: Interacts with the CDK1 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF). The cyclin subunit imparts substrate specificity to the complex.

8090:LOC101167211
gene id: 8090:LOC101167211
uniprot id: A0A3B3HZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

8090:LOC101159119
gene id: 8090:LOC101159119
uniprot id: H2M7A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

8090:LOC101163979
gene id: 8090:LOC101163979
uniprot id: A0A3P9JWP8
uniprot id: H2LRZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

8090:c5h12orf10
gene id: 8090:c5h12orf10
uniprot id: H2LKA5
names: Similarity
messages: Belongs to the MYG1 family.

8090:csnk1d
gene id: 8090:csnk1d
uniprot id: H2MS42
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:tmem254
gene id: 8090:tmem254
uniprot id: A0A3B3ILK7
names: Subcellular Location Annotation
messages: Membrane

8090:cct5
gene id: 8090:cct5
uniprot id: A0A3B3IBL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

8090:LOC101165391
gene id: 8090:LOC101165391
uniprot id: A0A3B3I1T4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:LOC101158162
gene id: 8090:LOC101158162
uniprot id: A0A3P9J9K7
uniprot id: H2MY23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

8090:LOC101167803
gene id: 8090:LOC101167803
uniprot id: H2LRU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Vesicle
messages: dendrite

8090:gpn3
gene id: 8090:gpn3
uniprot id: A0A3P9GXE4
uniprot id: H2M5C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

8090:sema3d
gene id: 8090:sema3d
uniprot id: A0A3B3H868
uniprot id: A0A3B3IL13
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:grin2b
gene id: 8090:grin2b
uniprot id: A0A3B3H4B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

8090:LOC101164587
gene id: 8090:LOC101164587
uniprot id: A0A3B3HUX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

8090:myc
gene id: 8090:myc
uniprot id: G3M8E7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

8090:mre11
gene id: 8090:mre11
uniprot id: H2LSP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

8090:LOC101160344
gene id: 8090:LOC101160344
uniprot id: A0A3B3HWG8
uniprot id: A0A3P9LP73
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

8090:LOC101171288
gene id: 8090:LOC101171288
uniprot id: H2MUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

8090:inip
gene id: 8090:inip
uniprot id: H2M7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

8090:dse
gene id: 8090:dse
uniprot id: A0A3B3IJ53
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

8090:mrpl33
gene id: 8090:mrpl33
uniprot id: A0A3P9HAE2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

8090:atg4b
gene id: 8090:atg4b
uniprot id: A0A3P9H736
uniprot id: H2L9R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

8090:LOC105356008
gene id: 8090:LOC105356008
uniprot id: A0A3B3HBN4
names: Subcellular Location Annotation
messages: Membrane

8090:gata6
gene id: 8090:gata6
uniprot id: H2MTL4
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101159204
gene id: 8090:LOC101159204
uniprot id: A0A3B3I0E7
uniprot id: A0A3B3I114
uniprot id: H2LYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

8090:LOC101172563
gene id: 8090:LOC101172563
uniprot id: H2LJ67
names: Similarity
messages: Belongs to the MAGUK family.

8090:LOC101171425
gene id: 8090:LOC101171425
uniprot id: H2MFH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:ackr3
gene id: 8090:ackr3
uniprot id: A0A3P9L533
uniprot id: H2MUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC100049225
gene id: 8090:LOC100049225
uniprot id: H2MTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:spast
gene id: 8090:spast
uniprot id: H2M9W7
names: Similarity
messages: Belongs to the AAA ATPase family.

8090:LOC101169936
gene id: 8090:LOC101169936
uniprot id: H2LJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

8090:LOC101157952
gene id: 8090:LOC101157952
uniprot id: H2LKF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

8090:rps15
gene id: 8090:rps15
uniprot id: A0A3P9MQ33
uniprot id: H2LLW5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Component of the small ribosomal subunit.

8090:llgl1
gene id: 8090:llgl1
uniprot id: H2MDD6
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

8090:actb
gene id: 8090:actb
uniprot id: P79818
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
messages: Belongs to the actin family.
messages: In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
messages: Methylation at His-73 by SETD3. Methylation stabilizes actin filaments.
messages: N-terminal cleavage of acetylated methionine of immature cytoplasmic actin by ACTMAP.
messages: Nucleus
messages: Oxidation of Met-44 and Met-47 by MICALs (mical1, mical2 or mical3) to form methionine sulfoxide promotes actin filament depolymerization. Mical1 and mical2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by msrb1 and msrb2, which promote actin repolymerization.
messages: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix (By similarity). Each actin can bind to 4 others (By similarity).
messages: cytoskeleton

8090:zdhhc8
gene id: 8090:zdhhc8
uniprot id: H2MJT4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:trmt11
gene id: 8090:trmt11
uniprot id: H2LMJ1
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

8090:LOC101171034
gene id: 8090:LOC101171034
uniprot id: A0A3B3IHB4
names: Similarity
messages: Belongs to the apolipoprotein L family.

8090:sppl3
gene id: 8090:sppl3
uniprot id: A0A3P9KZF0
uniprot id: H2M131
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

8090:gar1
gene id: 8090:gar1
uniprot id: A0A3P9KHE0
uniprot id: H2N227
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

8090:glra2
gene id: 8090:glra2
uniprot id: H2MU51
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

8090:LOC101158816
gene id: 8090:LOC101158816
uniprot id: A0A3P9I5H1
uniprot id: H2L385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

8090:LOC101174419
gene id: 8090:LOC101174419
uniprot id: H2MQ20
names: Similarity
messages: Belongs to the lipin family.

8090:LOC101173722
gene id: 8090:LOC101173722
uniprot id: A0A3B3IC87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

8090:LOC101171361
gene id: 8090:LOC101171361
uniprot id: H2LFN8
names: Similarity
messages: Belongs to the peptidase C1 family.

8090:adcy7
gene id: 8090:adcy7
uniprot id: A0A3B3H2F4
uniprot id: H2MFZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

8090:pmpca
gene id: 8090:pmpca
uniprot id: H2L4I1
names: Similarity
messages: Belongs to the peptidase M16 family.

8090:LOC101157289
gene id: 8090:LOC101157289
uniprot id: A0A3B3H3J7
uniprot id: A0A3P9IQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

8090:LOC101161678
gene id: 8090:LOC101161678
uniprot id: A0A3B3IHC7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:tmcc2
gene id: 8090:tmcc2
uniprot id: H2L3L6
names: Similarity
messages: Belongs to the TEX28 family.

8090:txnl4b
gene id: 8090:txnl4b
uniprot id: H2LJV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

8090:ppp1r13b
gene id: 8090:ppp1r13b
uniprot id: A0A3B3I3E2
uniprot id: H2MSM7
names: Subcellular Location Annotation
messages: Nucleus

8090:marcks
gene id: 8090:marcks
uniprot id: H2MUR4
names: Similarity
messages: Belongs to the MARCKS family.

8090:LOC101155461
gene id: 8090:LOC101155461
uniprot id: H2MIR1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

8090:atg12
gene id: 8090:atg12
uniprot id: A0A3P9HWA0
uniprot id: H2M7S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Ubiquitin-like protein involved in autophagic vesicle formation.

8090:foxp4
gene id: 8090:foxp4
uniprot id: C1K306
names: Subcellular Location Annotation
messages: Nucleus

8090:tmtc1
gene id: 8090:tmtc1
uniprot id: H2MCF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

8090:LOC101163572
gene id: 8090:LOC101163572
uniprot id: A0A3B3HVQ9
uniprot id: H2LRG0
names: Similarity
messages: Belongs to the DIP2 family.

8090:fmc1
gene id: 8090:fmc1
uniprot id: A0A3B3HTA3
names: Similarity
messages: Belongs to the FMC1 family.

8090:LOC101167186
gene id: 8090:LOC101167186
uniprot id: A0A3B3HPR9
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101165077
gene id: 8090:LOC101165077
uniprot id: A0A3B3II54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

8090:pik3r3
gene id: 8090:pik3r3
uniprot id: A0A3B3HQV4
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

8090:alox5ap
gene id: 8090:alox5ap
uniprot id: A0A3B3HMT8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101174845
gene id: 8090:LOC101174845
uniprot id: H2LPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

8090:LOC101164809
gene id: 8090:LOC101164809
uniprot id: H2MNM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

8090:LOC101154878
gene id: 8090:LOC101154878
uniprot id: A0A3P9KWA8
uniprot id: H2LVU0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:LOC101166777
gene id: 8090:LOC101166777
uniprot id: A0A3P9KU59
uniprot id: H2L2V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8090:fgf13
gene id: 8090:fgf13
uniprot id: A0A3P9LHN5
uniprot id: A0A3P9LI53
uniprot id: H2L861
uniprot id: H2L863
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

8090:LOC101158620
gene id: 8090:LOC101158620
uniprot id: A0A3B3HI85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

8090:wnt3a
gene id: 8090:wnt3a
uniprot id: A0A3B3HVS0
uniprot id: A0A3P9LYM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

8090:tex10
gene id: 8090:tex10
uniprot id: H2LY48
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

8090:LOC101173419
gene id: 8090:LOC101173419
uniprot id: H2M0D3
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

8090:LOC101175345
gene id: 8090:LOC101175345
uniprot id: A0A3P9L5G4
uniprot id: H2LRD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

8090:LOC101161659
gene id: 8090:LOC101161659
uniprot id: H2LKP8
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8090:grm2
gene id: 8090:grm2
uniprot id: A0A3B3I856
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8090:ddit4
gene id: 8090:ddit4
uniprot id: H2LZD2
names: Similarity
messages: Belongs to the DDIT4 family.

8090:ypelc
gene id: 8090:ypelc
uniprot id: A0A3P9KYD4
uniprot id: D2KVX6
names: Similarity
messages: Belongs to the yippee family.

8090:LOC101169232
gene id: 8090:LOC101169232
uniprot id: A0A3B3I3P2
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

8090:LOC101170239
gene id: 8090:LOC101170239
uniprot id: A0A3B3HR83
names: Subcellular Location Annotation
messages: nucleolus

8090:LOC101165525
gene id: 8090:LOC101165525
uniprot id: H2M4B4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

8090:LOC101170496
gene id: 8090:LOC101170496
uniprot id: H2MI38
names: Similarity
messages: Belongs to the TOM1 family.

8090:smim19
gene id: 8090:smim19
uniprot id: A0A3P9JFM8
uniprot id: H2LZU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

8090:LOC101174339
gene id: 8090:LOC101174339
uniprot id: A0A3B3IKM0
uniprot id: A0A3P9IMY2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:ndufb9
gene id: 8090:ndufb9
uniprot id: H2L4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8090:ttyh1
gene id: 8090:ttyh1
uniprot id: A0A3B3IJP7
uniprot id: A0A3P9HXN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

8090:LOC101159224
gene id: 8090:LOC101159224
uniprot id: A0A3B3IB95
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

8090:jak1
gene id: 8090:jak1
uniprot id: H2M2I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

8090:LOC101167667
gene id: 8090:LOC101167667
uniprot id: A0A3B3I5U9
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

8090:LOC101170168
gene id: 8090:LOC101170168
uniprot id: H2L772
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

8090:LOC101160140
gene id: 8090:LOC101160140
uniprot id: H2M3I5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101161996
gene id: 8090:LOC101161996
uniprot id: A0A3P9LWT8
uniprot id: H2LBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

8090:LOC101171076
gene id: 8090:LOC101171076
uniprot id: A0A3P9K5N4
uniprot id: H2LVY0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:tsr1
gene id: 8090:tsr1
uniprot id: H2LJL2
names: Subcellular Location Annotation
messages: nucleolus

8090:LOC101156185
gene id: 8090:LOC101156185
uniprot id: H2MH25
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

8090:LOC101162759
gene id: 8090:LOC101162759
uniprot id: A0A3B3HFJ1
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: May be an activator of the JNK/SAPK pathway.

8090:LOC101160349
gene id: 8090:LOC101160349
uniprot id: H2LV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

8090:LOC101167083
gene id: 8090:LOC101167083
uniprot id: A0A3P9H394
uniprot id: H2MN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

8090:med27
gene id: 8090:med27
uniprot id: A0A3B3HJP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

8090:LOC101169361
gene id: 8090:LOC101169361
uniprot id: H2MIA8
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

8090:tp53
gene id: 8090:tp53
uniprot id: P79820
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity).
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

8090:LOC101156778
gene id: 8090:LOC101156778
uniprot id: A0A3B3HTP4
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

8090:scarb1
gene id: 8090:scarb1
uniprot id: H2L6Z6
names: Similarity
messages: Belongs to the CD36 family.

8090:LOC101156080
gene id: 8090:LOC101156080
uniprot id: A0A3P9M8U5
uniprot id: H2LRJ6
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101155207
gene id: 8090:LOC101155207
uniprot id: A0A3B3I030
uniprot id: A0A3B3I637
uniprot id: A0A3P9J4I0
uniprot id: A0A3P9K389
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:apip
gene id: 8090:apip
uniprot id: H2L5W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

8090:LOC101160852
gene id: 8090:LOC101160852
uniprot id: H2LRZ9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

8090:cdkn1c
gene id: 8090:cdkn1c
uniprot id: H2L9Q4
names: Similarity
messages: Belongs to the CDI family.

8090:LOC101160850
gene id: 8090:LOC101160850
uniprot id: A0A3P9HQ65
uniprot id: H2LSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

8090:brox
gene id: 8090:brox
uniprot id: A0A3B3HU64
uniprot id: A0A3P9KB35
names: Similarity
messages: Belongs to the BROX family.

8090:LOC101161446
gene id: 8090:LOC101161446
uniprot id: A0A3B3HY49
uniprot id: A0A3P9MET3
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

8090:plppr4
gene id: 8090:plppr4
uniprot id: A0A3B3HRX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

8090:LOC100125517
gene id: 8090:LOC100125517
uniprot id: H2N1R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8090:LOC101158486
gene id: 8090:LOC101158486
uniprot id: H2LEA8
names: Similarity
messages: Belongs to the cytochrome b5 family.

8090:LOC101165093
gene id: 8090:LOC101165093
uniprot id: A0A3B3HQ45
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:adi1
gene id: 8090:adi1
uniprot id: H2MU93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

8090:mcoln2
gene id: 8090:mcoln2
uniprot id: H2LN93
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

8090:LOC101161656
gene id: 8090:LOC101161656
uniprot id: H2MBH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101165090
gene id: 8090:LOC101165090
uniprot id: H2M393
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:znf330
gene id: 8090:znf330
uniprot id: H2N0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

8090:ahr
gene id: 8090:ahr
uniprot id: Q90W03
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101166419
gene id: 8090:LOC101166419
uniprot id: H2MLF8
names: Similarity
messages: Belongs to the EEIG family.

8090:barhl1
gene id: 8090:barhl1
uniprot id: A0A3B3HJV6
names: Subcellular Location Annotation
messages: Nucleus

8090:cgrp1
gene id: 8090:cgrp1
uniprot id: Q05K87
names: Function
names: Similarity
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.

8090:fundc1
gene id: 8090:fundc1
uniprot id: A0A3P9HN97
uniprot id: H2MF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

8090:ccni
gene id: 8090:ccni
uniprot id: H2MK14
names: Function
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

8090:slc16a4
gene id: 8090:slc16a4
uniprot id: H2LP69
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101161432
gene id: 8090:LOC101161432
uniprot id: H2LZ94
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101155312
gene id: 8090:LOC101155312
uniprot id: A0A3B3I2K7
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

8090:trhr
gene id: 8090:trhr
uniprot id: A0A3P9JK35
uniprot id: E5RNB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

8090:LOC101157686
gene id: 8090:LOC101157686
uniprot id: H2LSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

8090:mc6ast3
gene id: 8090:mc6ast3
uniprot id: H2MYZ3
uniprot id: Q14TH6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101156401
gene id: 8090:LOC101156401
uniprot id: A0A3B3HKL9
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101166531
gene id: 8090:LOC101166531
uniprot id: A0A3B3H732
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm

8090:slc6a2
gene id: 8090:slc6a2
uniprot id: H2MER2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:LOC101175011
gene id: 8090:LOC101175011
uniprot id: A0A3B3I771
uniprot id: A0A3P9LQU1
names: Similarity
messages: Belongs to the syntaxin family.

8090:agpat4
gene id: 8090:agpat4
uniprot id: A0A3B3H5B5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

8090:LOC101163499
gene id: 8090:LOC101163499
uniprot id: H2MHE7
names: Similarity
messages: Belongs to the intermediate filament family.

8090:aco2
gene id: 8090:aco2
uniprot id: H2LBJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

8090:LOC101173825
gene id: 8090:LOC101173825
uniprot id: H2MIK1
names: Similarity
messages: Belongs to the peptidase M20A family.

8090:LOC101156292
gene id: 8090:LOC101156292
uniprot id: H2MK01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8090:fut9b
gene id: 8090:fut9b
uniprot id: Q5F2N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

8090:LOC101168800
gene id: 8090:LOC101168800
uniprot id: A0A3P9MFL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

8090:LOC101159027
gene id: 8090:LOC101159027
uniprot id: H2M127
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101170754
gene id: 8090:LOC101170754
uniprot id: A0A3B3HN81
names: Similarity
messages: Belongs to the copine family.

8090:cd82
gene id: 8090:cd82
uniprot id: A0A3B3H418
uniprot id: A0A3P9KTB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:tmem50a
gene id: 8090:tmem50a
uniprot id: A0A3B3I2R5
uniprot id: A0A3P9I1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

8090:aurkb
gene id: 8090:aurkb
uniprot id: B6ZIW4
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

8090:slc17a5
gene id: 8090:slc17a5
uniprot id: A0A3B3HS39
names: Subcellular Location Annotation
messages: Membrane

8090:arfgef1
gene id: 8090:arfgef1
uniprot id: A0A3B3I1N1
uniprot id: H2LWJ4
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

8090:pfas
gene id: 8090:pfas
uniprot id: H2MIR0
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

8090:LOC101155840
gene id: 8090:LOC101155840
uniprot id: A0A3B3I258
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:tmem70
gene id: 8090:tmem70
uniprot id: A0A3B3IKB9
names: Similarity
messages: Belongs to the TMEM70 family.

8090:LOC101170581
gene id: 8090:LOC101170581
uniprot id: H2M5Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

8090:lmnb2
gene id: 8090:lmnb2
uniprot id: H2LBQ7
names: Similarity
messages: Belongs to the intermediate filament family.

8090:asna1
gene id: 8090:asna1
uniprot id: A0A3P9LCE9
uniprot id: H2MHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer.

8090:ndufc1
gene id: 8090:ndufc1
uniprot id: A0A3B3HVH1
names: Similarity
names: Subunit
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.

8090:LOC101168797
gene id: 8090:LOC101168797
uniprot id: A0A3B3HRR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

8090:dimt1
gene id: 8090:dimt1
uniprot id: A0A3P9M4D9
uniprot id: H2LZ70
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

8090:LOC101161704
gene id: 8090:LOC101161704
uniprot id: H2LXW7
names: Subcellular Location Annotation
messages: Cytoplasm

8090:mgat5
gene id: 8090:mgat5
uniprot id: H2LHK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

8090:becn1
gene id: 8090:becn1
uniprot id: Q4A1L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beclin family.
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: autophagosome
messages: trans-Golgi network membrane

8090:LOC101155604
gene id: 8090:LOC101155604
uniprot id: A0A3B3HRY6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8090:chga
gene id: 8090:chga
uniprot id: H2MV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

8090:LOC101166342
gene id: 8090:LOC101166342
uniprot id: H2M229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

8090:LOC101163518
gene id: 8090:LOC101163518
uniprot id: H2LW30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:tmem267
gene id: 8090:tmem267
uniprot id: H2M931
names: Subcellular Location Annotation
messages: Membrane

8090:canx
gene id: 8090:canx
uniprot id: H2MWK1
names: Similarity
messages: Belongs to the calreticulin family.

8090:LOC101161755
gene id: 8090:LOC101161755
uniprot id: A0A3F2YNW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

8090:fam167b
gene id: 8090:fam167b
uniprot id: A0A3B3HQU5
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

8090:LOC100529159
gene id: 8090:LOC100529159
uniprot id: A0A3P9JCX7
uniprot id: Q5NUF5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8090:bbs10
gene id: 8090:bbs10
uniprot id: A0A3B3HD45
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

8090:exoc4
gene id: 8090:exoc4
uniprot id: A0A3P9MDH7
uniprot id: H2MHU7
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

8090:LOC101160775
gene id: 8090:LOC101160775
uniprot id: A0A3B3HXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

8090:LOC101172314
gene id: 8090:LOC101172314
uniprot id: A0A3B3HU15
uniprot id: A0A3B3HWY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the interleukin-1 receptor family.
messages: Membrane

8090:kynu
gene id: 8090:kynu
uniprot id: H2LK45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:itpk1
gene id: 8090:itpk1
uniprot id: A0A3B3H8N1
uniprot id: A0A3B3HPP4
uniprot id: A0A3P9M0E3
uniprot id: A0A3P9M171
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ITPK1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.
messages: Monomer.

8090:LOC101166173
gene id: 8090:LOC101166173
uniprot id: A0A3P9LGW2
uniprot id: H2M795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

8090:LOC101174341
gene id: 8090:LOC101174341
uniprot id: H2MKQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

8090:tbc1d23
gene id: 8090:tbc1d23
uniprot id: H2MN61
uniprot id: H2MN63
names: Subcellular Location Annotation
messages: trans-Golgi network

8090:zwilch
gene id: 8090:zwilch
uniprot id: A0A3B3IAK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

8090:kif3b
gene id: 8090:kif3b
uniprot id: H2LAE9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:suclg1
gene id: 8090:suclg1
uniprot id: A0A3P9IML9
uniprot id: H2LNN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

8090:LOC101174129
gene id: 8090:LOC101174129
uniprot id: A0A3B3I0A5
names: Similarity
messages: Belongs to the FXYD family.

8090:LOC105355366
gene id: 8090:LOC105355366
uniprot id: A0A3P9KTK9
uniprot id: H2LSN9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

8090:LOC101173659
gene id: 8090:LOC101173659
uniprot id: H2LD50
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

8090:LOC101155506
gene id: 8090:LOC101155506
uniprot id: A0A3B3HUJ6
names: Similarity
messages: Belongs to the PP2C family.

8090:palmd
gene id: 8090:palmd
uniprot id: A0A3B3I321
names: Similarity
messages: Belongs to the paralemmin family.

8090:slc41a3
gene id: 8090:slc41a3
uniprot id: H2L6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

8090:tmod3
gene id: 8090:tmod3
uniprot id: A0A3P9MNM8
uniprot id: H2LD09
names: Subcellular Location Annotation
messages: cytoskeleton

8090:myod1
gene id: 8090:myod1
uniprot id: A0A3B3IPA5
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

8090:ahdc1
gene id: 8090:ahdc1
uniprot id: A0A3B3I0N0
names: Subcellular Location Annotation
messages: Nucleus

8090:megf10
gene id: 8090:megf10
uniprot id: H2MIG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101156109
gene id: 8090:LOC101156109
uniprot id: H2LB03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

8090:LOC101171526
gene id: 8090:LOC101171526
uniprot id: A0A3P9MC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

8090:LOC101166610
gene id: 8090:LOC101166610
uniprot id: H2LBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

8090:LOC101164098
gene id: 8090:LOC101164098
uniprot id: A0A3B3HY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

8090:strn3
gene id: 8090:strn3
uniprot id: H2M4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

8090:optn
gene id: 8090:optn
uniprot id: H2N2R3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

8090:LOC101169570
gene id: 8090:LOC101169570
uniprot id: H2M242
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

8090:timp2
gene id: 8090:timp2
uniprot id: A0A3P9LPI1
uniprot id: Q4W888
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

8090:chst8
gene id: 8090:chst8
uniprot id: A0A3B3HM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101167777
gene id: 8090:LOC101167777
uniprot id: H2MKD3
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101155449
gene id: 8090:LOC101155449
uniprot id: H2L5R4
names: Similarity
messages: Belongs to the alpha-actinin family.

8090:ncaph2
gene id: 8090:ncaph2
uniprot id: H2N092
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

8090:LOC101172828
gene id: 8090:LOC101172828
uniprot id: A0A3B3IF29
uniprot id: A0A3P9JA39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

8090:LOC101173804
gene id: 8090:LOC101173804
uniprot id: H2L8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

8090:LOC101171064
gene id: 8090:LOC101171064
uniprot id: A0A3B3I4I5
names: Similarity
messages: Belongs to the TGF-beta family.

8090:crybg1
gene id: 8090:crybg1
uniprot id: H2MBV5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC101155544
gene id: 8090:LOC101155544
uniprot id: H2M419
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

8090:LOC101171031
gene id: 8090:LOC101171031
uniprot id: A0A3B3HA42
uniprot id: A0A3P9KQP6
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

8090:tmem231
gene id: 8090:tmem231
uniprot id: H2MK03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

8090:mau2
gene id: 8090:mau2
uniprot id: A0A3P9HG14
uniprot id: H2L570
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

8090:abt1
gene id: 8090:abt1
uniprot id: A0A3B3H5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

8090:gadd45a
gene id: 8090:gadd45a
uniprot id: Q3LG54
names: Similarity
messages: Belongs to the GADD45 family.

8090:st6galnac4
gene id: 8090:st6galnac4
uniprot id: Q5K024
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

8090:anxa4
gene id: 8090:anxa4
uniprot id: O93444
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

8090:LOC101158678
gene id: 8090:LOC101158678
uniprot id: H2MVR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

8090:mcee
gene id: 8090:mcee
uniprot id: A0A3B3IGA1
uniprot id: A0A3P9KYE4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

8090:cmtr1
gene id: 8090:cmtr1
uniprot id: H2MFF4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

8090:ipmk
gene id: 8090:ipmk
uniprot id: A0A3B3I6S4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

8090:LOC101173816
gene id: 8090:LOC101173816
uniprot id: A0A3P9M8Q7
uniprot id: H2LAW8
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Component of the 43S pre-initiation complex (43S PIC), which binds to the mRNA cap-proximal region, scans mRNA 5'-untranslated region, and locates the initiation codon. This protein enhances formation of the cap-proximal complex. Together with EIF1, facilitates scanning, start codon recognition, promotion of the assembly of 48S complex at the initiation codon (43S PIC becomes 48S PIC after the start codon is reached), and dissociation of aberrant complexes. After start codon location, together with EIF5B orients the initiator methionine-tRNA in a conformation that allows 60S ribosomal subunit joining to form the 80S initiation complex. Is released after 80S initiation complex formation, just after GTP hydrolysis by EIF5B, and before release of EIF5B. Its globular part is located in the A site of the 40S ribosomal subunit. Its interaction with EIF5 during scanning contribute to the maintenance of EIF1 within the open 43S PIC. In contrast to yeast orthologs, does not bind EIF1.

8090:prss56
gene id: 8090:prss56
uniprot id: H2MLX2
names: Subcellular Location Annotation
messages: extracellular space

8090:mycn
gene id: 8090:mycn
uniprot id: A0A3B3HU75
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

8090:wdpcp
gene id: 8090:wdpcp
uniprot id: A0A3B3H778
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

8090:hpn
gene id: 8090:hpn
uniprot id: H2LNJ0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8090:LOC101156250
gene id: 8090:LOC101156250
uniprot id: A0A3P9JB12
uniprot id: H2M9N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

8090:lef1
gene id: 8090:lef1
uniprot id: A0A3P9IID1
uniprot id: A0A3P9JQK1
uniprot id: A0A3P9MMJ9
uniprot id: H2LRJ8
uniprot id: H2LRK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

8090:eif4a2
gene id: 8090:eif4a2
uniprot id: H2LY80
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

8090:kpna4
gene id: 8090:kpna4
uniprot id: A0A3P9HCZ9
uniprot id: H2LP51
names: Similarity
messages: Belongs to the importin alpha family.

8090:LOC101171628
gene id: 8090:LOC101171628
uniprot id: H2MV64
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

8090:smpd2
gene id: 8090:smpd2
uniprot id: H2LPH4
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

8090:LOC101168648
gene id: 8090:LOC101168648
uniprot id: A0A3P9MJF7
uniprot id: R4N1B0
names: Similarity
messages: Belongs to the FXYD family.

8090:pgap1
gene id: 8090:pgap1
uniprot id: H2MVK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101155619
gene id: 8090:LOC101155619
uniprot id: A0A3B3ING7
names: Similarity
messages: Belongs to the GADD45 family.

8090:LOC101173221
gene id: 8090:LOC101173221
uniprot id: A0A3B3HUH2
names: Subcellular Location Annotation
messages: Membrane

8090:atf7ip
gene id: 8090:atf7ip
uniprot id: A0A3B3I292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

8090:LOC101166668
gene id: 8090:LOC101166668
uniprot id: H2LWV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:dxo
gene id: 8090:dxo
uniprot id: H2LXX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

8090:cckar
gene id: 8090:cckar
uniprot id: H2LRS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:phkb
gene id: 8090:phkb
uniprot id: H2MJU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

8090:mtrf1l
gene id: 8090:mtrf1l
uniprot id: H2LG05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

8090:rab9a
gene id: 8090:rab9a
uniprot id: A0A3P9MGX1
uniprot id: H2MU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

8090:nup205
gene id: 8090:nup205
uniprot id: H2MMP8
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

8090:LOC101170807
gene id: 8090:LOC101170807
uniprot id: A0A3B3H768
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Membrane
messages: Mitochondrion inner membrane

8090:cenpk
gene id: 8090:cenpk
uniprot id: H2MBJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

8090:LOC101157469
gene id: 8090:LOC101157469
uniprot id: H2MH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

8090:LOC101158877
gene id: 8090:LOC101158877
uniprot id: A0A3B3HQR1
uniprot id: H2LYC7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

8090:LOC101154978
gene id: 8090:LOC101154978
uniprot id: A0A3P9HUY8
uniprot id: H2L9C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

8090:tmem184a
gene id: 8090:tmem184a
uniprot id: H2LIQ8
names: Subcellular Location Annotation
messages: Membrane

8090:eif6
gene id: 8090:eif6
uniprot id: H2LCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

8090:LOC101173456
gene id: 8090:LOC101173456
uniprot id: A0A3P9IF49
uniprot id: H2MHE3
names: Similarity
messages: Belongs to the WD repeat EBI family.

8090:LOC100125490
gene id: 8090:LOC100125490
uniprot id: A0A3B3H516
uniprot id: A0A3P9KEK4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

8090:LOC101156771
gene id: 8090:LOC101156771
uniprot id: A0A3B3HLC9
uniprot id: A0A3B3IHQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

8090:zfpm2
gene id: 8090:zfpm2
uniprot id: H2LDM5
names: Subcellular Location Annotation
messages: Nucleus

8090:smad3
gene id: 8090:smad3
uniprot id: H2LR51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

8090:LOC101161108
gene id: 8090:LOC101161108
uniprot id: H2LZC9
names: Similarity
messages: Belongs to the ARTD/PARP family.

8090:LOC101174968
gene id: 8090:LOC101174968
uniprot id: A0A3B3HC24
uniprot id: A0A3P9J2A5
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

8090:LOC101168000
gene id: 8090:LOC101168000
uniprot id: A0A3P9HZQ1
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

8090:LOC101159440
gene id: 8090:LOC101159440
uniprot id: A0A3B3HFI9
uniprot id: A0A3P9JDT1
uniprot id: A0A3P9LMU1
uniprot id: H2LQ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

8090:LOC101158770
gene id: 8090:LOC101158770
uniprot id: A0A3B3IG41
uniprot id: A0A3P9K908
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

8090:acot13
gene id: 8090:acot13
uniprot id: A0A3P9JDZ4
uniprot id: H2MC10
names: Similarity
messages: Belongs to the thioesterase PaaI family.

8090:eef1a
gene id: 8090:eef1a
uniprot id: Q9YIC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Translation elongation factor that catalyzes the GTP-dependent binding of aminoacyl-tRNA (aa-tRNA) to the A-site of ribosomes during the elongation phase of protein synthesis. Base pairing between the mRNA codon and the aa-tRNA anticodon promotes GTP hydrolysis, releasing the aa-tRNA from EEF1A1 and allowing its accommodation into the ribosome. The growing protein chain is subsequently transferred from the P-site peptidyl tRNA to the A-site aa-tRNA, extending it by one amino acid through ribosome-catalyzed peptide bond formation.

8090:ndufa5
gene id: 8090:ndufa5
uniprot id: A0A3P9LDT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

8090:LOC101166755
gene id: 8090:LOC101166755
uniprot id: H2LSA0
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

8090:LOC101175684
gene id: 8090:LOC101175684
uniprot id: A0A3B3HL23
uniprot id: A0A3B3IAZ8
uniprot id: A0A3B3IJW1
uniprot id: H2MLS8
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

8090:supt16h
gene id: 8090:supt16h
uniprot id: H2LXY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

8090:fez1
gene id: 8090:fez1
uniprot id: A0A3P9HMY5
uniprot id: H2MWI5
names: Similarity
messages: Belongs to the zygin family.

8090:mrs2
gene id: 8090:mrs2
uniprot id: H2LIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

8090:nprl2
gene id: 8090:nprl2
uniprot id: A0A3B3I132
names: Similarity
messages: Belongs to the NPR2 family.

8090:uvssa
gene id: 8090:uvssa
uniprot id: H2M5A6
names: Similarity
messages: Belongs to the UVSSA family.

8090:LOC101166928
gene id: 8090:LOC101166928
uniprot id: H2MX83
names: Subcellular Location Annotation
messages: Membrane

8090:caprin2
gene id: 8090:caprin2
uniprot id: H2MB34
names: Similarity
messages: Belongs to the caprin family.

8090:mtmr9
gene id: 8090:mtmr9
uniprot id: H2MP75
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8090:LOC101158407
gene id: 8090:LOC101158407
uniprot id: H2MRB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Oligomer.

8090:LOC101162070
gene id: 8090:LOC101162070
uniprot id: H2MQI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

8090:prmt3
gene id: 8090:prmt3
uniprot id: H2L5E9
names: Subcellular Location Annotation
messages: Cytoplasm

8090:ppif
gene id: 8090:ppif
uniprot id: H2LYD7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

8090:mc6ast5
gene id: 8090:mc6ast5
uniprot id: Q14TH4
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:ggact
gene id: 8090:ggact
uniprot id: A0A3B3IEQ8
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.

8090:nek9
gene id: 8090:nek9
uniprot id: H2MPF6
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

8090:eva1c
gene id: 8090:eva1c
uniprot id: H2LHH4
names: Similarity
messages: Belongs to the EVA1 family.

8090:tnfsf10
gene id: 8090:tnfsf10
uniprot id: A0A3P9I9P7
uniprot id: H2M8M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

8090:LOC101171904
gene id: 8090:LOC101171904
uniprot id: H2LGD1
names: Similarity
messages: Belongs to the FAM83 family.

8090:cftr
gene id: 8090:cftr
uniprot id: H2MZ50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Membrane
messages: Recycling endosome membrane

8090:LOC101170230
gene id: 8090:LOC101170230
uniprot id: A0A3B3HN83
names: Similarity
messages: Belongs to the TGF-beta family.

8090:LOC101166728
gene id: 8090:LOC101166728
uniprot id: A0A3B3IC08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

8090:igsf11
gene id: 8090:igsf11
uniprot id: A0A3B3HWZ4
uniprot id: A0A3P9IC17
names: Subcellular Location Annotation
messages: Membrane

8090:rtn1
gene id: 8090:rtn1
uniprot id: A0A3B3HF60
uniprot id: A0A3P9KJM1
uniprot id: A0A3P9M1M3
uniprot id: H2MM70
uniprot id: Q6IEI8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101171752
gene id: 8090:LOC101171752
uniprot id: H2LAB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8090:tacr3
gene id: 8090:tacr3
uniprot id: H2LNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:LOC101158638
gene id: 8090:LOC101158638
uniprot id: A0A3B3IDI9
names: Subcellular Location Annotation
messages: Synapse

8090:LOC101168028
gene id: 8090:LOC101168028
uniprot id: A0A3P9LM07
uniprot id: H2MBQ3
names: Similarity
messages: Belongs to the Bcl-2 family.

8090:ablim2
gene id: 8090:ablim2
uniprot id: H2N082
names: Subcellular Location Annotation
messages: Cytoplasm

8090:nfe2l1
gene id: 8090:nfe2l1
uniprot id: H2MA96
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

8090:sulf1
gene id: 8090:sulf1
uniprot id: A0A3B3HV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack

8090:LOC101162259
gene id: 8090:LOC101162259
uniprot id: A0A3P9IQP6
uniprot id: H2MMD3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

8090:cct7
gene id: 8090:cct7
uniprot id: H2LMQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

8090:dlx5
gene id: 8090:dlx5
uniprot id: A0A3P9K2I5
uniprot id: H2LIB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

8090:spcs1
gene id: 8090:spcs1
uniprot id: H2MMS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101172253
gene id: 8090:LOC101172253
uniprot id: A0A3B3ILF2
uniprot id: A0A3P9J1V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

8090:LOC101170331
gene id: 8090:LOC101170331
uniprot id: H2MVP0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

8090:LOC101162799
gene id: 8090:LOC101162799
uniprot id: H2MSZ2
uniprot id: H2MSZ3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

8090:vps28
gene id: 8090:vps28
uniprot id: A0A3P9JD04
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

8090:bet1
gene id: 8090:bet1
uniprot id: A0A3P9I133
names: Subcellular Location Annotation
messages: Membrane

8090:cfap300
gene id: 8090:cfap300
uniprot id: H2M9B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

8090:capn10
gene id: 8090:capn10
uniprot id: H2MLU5
names: Similarity
messages: Belongs to the peptidase C2 family.

8090:LOC101164501
gene id: 8090:LOC101164501
uniprot id: A0A3P9L2K1
uniprot id: H2M8P3
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8090:LOC101155075
gene id: 8090:LOC101155075
uniprot id: A0A3B3I2E8
names: Similarity
messages: Belongs to the NXPE family.

8090:cacng5
gene id: 8090:cacng5
uniprot id: A0A3P9ILI4
uniprot id: H2MFJ6
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

8090:bmp6
gene id: 8090:bmp6
uniprot id: A0A3P9JSR1
uniprot id: H2LQ66
names: Similarity
messages: Belongs to the TGF-beta family.

8090:LOC101159043
gene id: 8090:LOC101159043
uniprot id: A0A3B3ID02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

8090:smg9
gene id: 8090:smg9
uniprot id: A0A3P9MIR0
uniprot id: H2LPK9
names: Similarity
messages: Belongs to the SMG9 family.

8090:serpinf2
gene id: 8090:serpinf2
uniprot id: H2LJA4
names: Similarity
messages: Belongs to the serpin family.

8090:slc25a19
gene id: 8090:slc25a19
uniprot id: H2M139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

8090:cdca5
gene id: 8090:cdca5
uniprot id: H2M1F1
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

8090:LOC101163834
gene id: 8090:LOC101163834
uniprot id: A0A3B3H6K2
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.

8090:kcnk18
gene id: 8090:kcnk18
uniprot id: A0A3B3H859
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

8090:LOC101157143
gene id: 8090:LOC101157143
uniprot id: H2MBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

8090:rpl8
gene id: 8090:rpl8
uniprot id: A0A3P9KZL5
uniprot id: A0FDJ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

8090:LOC101156099
gene id: 8090:LOC101156099
uniprot id: A0A3B3HV75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

8090:ap5m1
gene id: 8090:ap5m1
uniprot id: A0A3B3IMJ7
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

8090:LOC105354405
gene id: 8090:LOC105354405
uniprot id: A0A3B3HZU1
names: Subcellular Location Annotation
messages: Nucleus

8090:dpysl5
gene id: 8090:dpysl5
uniprot id: H2MTK4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

8090:LOC101159688
gene id: 8090:LOC101159688
uniprot id: H2L723
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

8090:LOC101161499
gene id: 8090:LOC101161499
uniprot id: H2LBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

8090:apmap
gene id: 8090:apmap
uniprot id: A0A3P9L4T6
uniprot id: H2LCZ3
names: Similarity
messages: Belongs to the strictosidine synthase family.

8090:nr3c1
gene id: 8090:nr3c1
uniprot id: H2L7X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

8090:pax7
gene id: 8090:pax7
uniprot id: A0A060N113
uniprot id: A0A3B3HI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

8090:dhodh
gene id: 8090:dhodh
uniprot id: H2LMM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

8090:cct8
gene id: 8090:cct8
uniprot id: A0A3B3IAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

8090:LOC101156809
gene id: 8090:LOC101156809
uniprot id: A0A3P9L3A1
names: Function
names: Similarity
messages: Belongs to the janus family.
messages: Exhibits phosphohistidine phosphatase activity.

8090:mansc1
gene id: 8090:mansc1
uniprot id: A0A3B3HSZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

8090:gjd2
gene id: 8090:gjd2
uniprot id: A0A3B3HR27
uniprot id: A0A3P9I395
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

8090:rad18
gene id: 8090:rad18
uniprot id: A0A3B3I8Z2
uniprot id: A0A3B3IBR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

8090:dll1
gene id: 8090:dll1
uniprot id: H2M4D6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

8090:LOC101172154
gene id: 8090:LOC101172154
uniprot id: A0A3B3H9B2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:nr0b2
gene id: 8090:nr0b2
uniprot id: H2LHV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

8090:LOC101168285
gene id: 8090:LOC101168285
uniprot id: A0A3B3HEY5
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:sfr1
gene id: 8090:sfr1
uniprot id: A0A3B3I316
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

8090:LOC101162458
gene id: 8090:LOC101162458
uniprot id: H2LE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101168388
gene id: 8090:LOC101168388
uniprot id: A0A3B3IH63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

8090:sema5b
gene id: 8090:sema5b
uniprot id: A0A3B3HQB2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC105354517
gene id: 8090:LOC105354517
uniprot id: H2LB87
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

8090:nol6
gene id: 8090:nol6
uniprot id: H2M2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
messages: nucleolus

8090:LOC101164878
gene id: 8090:LOC101164878
uniprot id: H2LQW3
names: Similarity
messages: Belongs to the cytochrome P450 family.

8090:prim1
gene id: 8090:prim1
uniprot id: H2MA22
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

8090:krtcap3
gene id: 8090:krtcap3
uniprot id: H2M6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

8090:rpl23
gene id: 8090:rpl23
uniprot id: A0A3P9HH38
uniprot id: H2MY25
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

8090:lin28b
gene id: 8090:lin28b
uniprot id: A0A3B3HMI1
uniprot id: H2MC70
names: Similarity
messages: Belongs to the lin-28 family.

8090:anapc16
gene id: 8090:anapc16
uniprot id: A0A3P9HCN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

8090:meltf
gene id: 8090:meltf
uniprot id: H2M6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.

8090:sez6l2
gene id: 8090:sez6l2
uniprot id: H2M697
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:derl2
gene id: 8090:derl2
uniprot id: A0A3P9JTD5
uniprot id: H2MB52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

8090:LOC101172489
gene id: 8090:LOC101172489
uniprot id: A0A3P9KPF5
uniprot id: H2LKY0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:srfbp1
gene id: 8090:srfbp1
uniprot id: H2MGW0
names: Function
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

8090:exosc3
gene id: 8090:exosc3
uniprot id: A0A3B3HMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm
messages: nucleolus

8090:lif
gene id: 8090:lif
uniprot id: A0A060N3C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

8090:slc16a12
gene id: 8090:slc16a12
uniprot id: H2N1G4
names: Subcellular Location Annotation
messages: Membrane

8090:gtf2e1
gene id: 8090:gtf2e1
uniprot id: H2N1N7
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.

8090:LOC101161606
gene id: 8090:LOC101161606
uniprot id: A0A3B3HEP0
uniprot id: A0A3P9M2D4
names: Similarity
messages: Belongs to the p23/wos2 family.

8090:stk33
gene id: 8090:stk33
uniprot id: H2LRD1
names: Similarity
messages: Belongs to the protein kinase superfamily.

8090:acads
gene id: 8090:acads
uniprot id: H2L6A8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

8090:LOC101164671
gene id: 8090:LOC101164671
uniprot id: H2M852
uniprot id: H2M857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

8090:LOC101168600
gene id: 8090:LOC101168600
uniprot id: H2M777
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

8090:ackr4
gene id: 8090:ackr4
uniprot id: H2M351
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:ppp4r2
gene id: 8090:ppp4r2
uniprot id: H2M5R0
names: Similarity
messages: Belongs to the PPP4R2 family.

8090:LOC101156872
gene id: 8090:LOC101156872
uniprot id: A0A3B3IJD6
uniprot id: A0A3P9ITV0
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

8090:ube2d2
gene id: 8090:ube2d2
uniprot id: A0A3P9I0H3
uniprot id: H2M178
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

8090:LOC101173529
gene id: 8090:LOC101173529
uniprot id: H2MHV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

8090:etfdh
gene id: 8090:etfdh
uniprot id: H2N0Z8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

8090:pkn2
gene id: 8090:pkn2
uniprot id: H2LJF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

8090:grk4
gene id: 8090:grk4
uniprot id: A0A3B3H7F6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

8090:LOC101168098
gene id: 8090:LOC101168098
uniprot id: H2MH22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC101162833
gene id: 8090:LOC101162833
uniprot id: H2MK25
names: Subcellular Location Annotation
messages: Membrane

8090:ilvbl
gene id: 8090:ilvbl
uniprot id: H2MI57
names: Similarity
messages: Belongs to the TPP enzyme family.

8090:LOC101169741
gene id: 8090:LOC101169741
uniprot id: A0A3B3H593
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Membrane

8090:fech
gene id: 8090:fech
uniprot id: A0A3B3IEG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

8090:slc45a3
gene id: 8090:slc45a3
uniprot id: H2MLV2
names: Subcellular Location Annotation
messages: Membrane

8090:abcg5
gene id: 8090:abcg5
uniprot id: H2LIM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

8090:LOC101154988
gene id: 8090:LOC101154988
uniprot id: H2M2E5
names: Similarity
messages: Belongs to the EAF family.

8090:LOC101159952
gene id: 8090:LOC101159952
uniprot id: A0A3B3HR13
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

8090:LOC101164388
gene id: 8090:LOC101164388
uniprot id: H2LXR0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:stac3
gene id: 8090:stac3
uniprot id: A0A3P9L5T0
names: Subcellular Location Annotation
messages: sarcolemma

8090:hoxb5
gene id: 8090:hoxb5
uniprot id: A0A3P9MQ82
uniprot id: Q3V611
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

8090:LOC101156655
gene id: 8090:LOC101156655
uniprot id: A0A3B3IKW2
names: Subcellular Location Annotation
messages: Membrane

8090:oxct1
gene id: 8090:oxct1
uniprot id: H2LGX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

8090:ppie
gene id: 8090:ppie
uniprot id: A0A3B3HAZ3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

8090:cdk1
gene id: 8090:cdk1
uniprot id: Q9DGD3
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Forms a stable but non-covalent complex with cyclin B in mature oocytes.
messages: Nucleus
messages: Phosphorylation at Thr-14 or Tyr-15 inactivates the enzyme, while phosphorylation at Thr-161 activates it.
messages: Phosphorylation at Tyr-15 by wee1 and wee2 inhibits the protein kinase activity and acts negative regulator of entry into mitosis (G2 to M transition).
messages: Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition via association with multiple interphase cyclins. May play a role in regulating the amplitude of the cyclic expression of circadian clock genes.
messages: centrosome

8090:rps25
gene id: 8090:rps25
uniprot id: A0A3P9JPG6
uniprot id: H2MCW3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

8090:LOC101156992
gene id: 8090:LOC101156992
uniprot id: A0A3B3HT21
names: Similarity
messages: Belongs to the FBPase class 1 family.

8090:rspo2
gene id: 8090:rspo2
uniprot id: A0A3P9JXF4
uniprot id: G0ZE07
names: Similarity
messages: Belongs to the R-spondin family.

8090:c8a
gene id: 8090:c8a
uniprot id: A0A3B3I8Z1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

8090:tmem11
gene id: 8090:tmem11
uniprot id: A0A3P9IT89
uniprot id: H2M7H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Plays a role in mitochondrial morphogenesis.

8090:LOC101158094
gene id: 8090:LOC101158094
uniprot id: H2N1Q3
names: Subcellular Location Annotation
messages: extracellular space

8090:LOC101155764
gene id: 8090:LOC101155764
uniprot id: H2MEG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

8090:LOC101166394
gene id: 8090:LOC101166394
uniprot id: A0A3B3IBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)). Interacts with UQCC6.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

8090:dbh
gene id: 8090:dbh
uniprot id: A0A3B3IB38
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

8090:LOC101169056
gene id: 8090:LOC101169056
uniprot id: H2MDS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

8090:vkorc1
gene id: 8090:vkorc1
uniprot id: H2LQ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:coq4
gene id: 8090:coq4
uniprot id: H2LSD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

8090:LOC101166392
gene id: 8090:LOC101166392
uniprot id: A0A3P9LBY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

8090:pan2
gene id: 8090:pan2
uniprot id: A0A3B3H4Q7
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

8090:LOC101165490
gene id: 8090:LOC101165490
uniprot id: A0A3B3HTJ6
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

8090:parp2
gene id: 8090:parp2
uniprot id: A0A3B3IL62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

8090:LOC101171417
gene id: 8090:LOC101171417
uniprot id: A0A3P9I3I2
uniprot id: H2LB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

8090:slc30a1
gene id: 8090:slc30a1
uniprot id: A0A3B3HC26
uniprot id: A0A3P9MCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

8090:tbr1
gene id: 8090:tbr1
uniprot id: A0A3P9IB14
uniprot id: H2MQN1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

8090:tacr2
gene id: 8090:tacr2
uniprot id: H2M3S0
uniprot id: I4IY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

8090:wrnip1
gene id: 8090:wrnip1
uniprot id: H2MS61
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

8090:LOC101167443
gene id: 8090:LOC101167443
uniprot id: A0A3B3HCS4
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101159830
gene id: 8090:LOC101159830
uniprot id: A0A3B3HLF5
uniprot id: H2MQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

8090:LOC101168127
gene id: 8090:LOC101168127
uniprot id: H2LWR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

8090:rps11
gene id: 8090:rps11
uniprot id: A0A3P9LW02
uniprot id: H2LID3
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

8090:tecpr1
gene id: 8090:tecpr1
uniprot id: A0A3B3INJ8
names: Similarity
messages: Belongs to the TECPR1 family.

8090:dcp1a
gene id: 8090:dcp1a
uniprot id: H2LE76
names: Similarity
messages: Belongs to the DCP1 family.

8090:six1
gene id: 8090:six1
uniprot id: A0A3P9HJ42
uniprot id: H2MM02
names: Subcellular Location Annotation
messages: Nucleus

8090:lmbr1l
gene id: 8090:lmbr1l
uniprot id: A0A3B3HIY5
names: Similarity
messages: Belongs to the LIMR family.

8090:LOC105357606
gene id: 8090:LOC105357606
uniprot id: A0A3B3INL2
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:cga
gene id: 8090:cga
uniprot id: A7UDN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer of an alpha and a beta chain.
messages: Secreted

8090:LOC101157555
gene id: 8090:LOC101157555
uniprot id: A0A3P9GZD6
uniprot id: H2LBE7
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

8090:LOC101171632
gene id: 8090:LOC101171632
uniprot id: A0A3P9IHC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

8090:LOC101163862
gene id: 8090:LOC101163862
uniprot id: H2MV16
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:LOC101160913
gene id: 8090:LOC101160913
uniprot id: A0A3P9L4P4
uniprot id: H2LPD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

8090:fam102b
gene id: 8090:fam102b
uniprot id: A0A3B3I3H1
names: Similarity
messages: Belongs to the EEIG family.

8090:LOC101163757
gene id: 8090:LOC101163757
uniprot id: H2MEV4
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

8090:LOC101173752
gene id: 8090:LOC101173752
uniprot id: H2MVK0
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101168997
gene id: 8090:LOC101168997
uniprot id: H2LSU5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

8090:fbxo25
gene id: 8090:fbxo25
uniprot id: A0A3B3HMP7
uniprot id: H2MFJ1
names: Subcellular Location Annotation
messages: Nucleus

8090:LOC101161072
gene id: 8090:LOC101161072
uniprot id: H2M0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

8090:pou4f1
gene id: 8090:pou4f1
uniprot id: A0A3P9JGU7
uniprot id: H2LHW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

8090:nppa
gene id: 8090:nppa
uniprot id: A0A3P9MRA5
uniprot id: Q7T1Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Exhibits natriuretic and vasodepressant activity. Has cGMP-stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments.
messages: Secreted

8090:msh5
gene id: 8090:msh5
uniprot id: H2LZA0
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

8090:pyroxd1
gene id: 8090:pyroxd1
uniprot id: A0A3B3HFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

8090:timm10
gene id: 8090:timm10
uniprot id: A0A3B3HS92
uniprot id: A0A3P9HBV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

8090:cfl1
gene id: 8090:cfl1
uniprot id: A0A3P9HLN3
uniprot id: H2L9S1
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

8090:LOC101167791
gene id: 8090:LOC101167791
uniprot id: H2L812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

8090:LOC101157054
gene id: 8090:LOC101157054
uniprot id: H2L884
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

8090:LOC101163178
gene id: 8090:LOC101163178
uniprot id: H2LDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

8090:LOC101162525
gene id: 8090:LOC101162525
uniprot id: H2MPE4
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

8090:chst12
gene id: 8090:chst12
uniprot id: H2LYB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:LOC101175475
gene id: 8090:LOC101175475
uniprot id: A0A3P9L432
uniprot id: H2ML65
names: Similarity
messages: Belongs to the canopy family.

8090:mblac1
gene id: 8090:mblac1
uniprot id: H2M4E0
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

8090:emc7
gene id: 8090:emc7
uniprot id: H2MU71
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

8090:LOC105354745
gene id: 8090:LOC105354745
uniprot id: A0A3B3I4H3
names: Similarity
messages: Belongs to the arrestin family.

c2
gene id: 8090:bf/c2
uniprot id: A0A3P9KH11
uniprot id: P79816
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

8090:ppip5k1
gene id: 8090:ppip5k1
uniprot id: A0A3B3H5M3
uniprot id: A0A3B3I083
uniprot id: H2L330
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

8090:sumo2
gene id: 8090:sumo2
uniprot id: C9E6G1
uniprot id: C9E6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

8090:noc3l
gene id: 8090:noc3l
uniprot id: H2MYR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

8090:LOC101169650
gene id: 8090:LOC101169650
uniprot id: H2MVI5
names: Subcellular Location Annotation
messages: Membrane

8090:mboat1
gene id: 8090:mboat1
uniprot id: H2LJR3
names: Subcellular Location Annotation
messages: Membrane

8090:LOC101158139
gene id: 8090:LOC101158139
uniprot id: H2MTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

8090:LOC101166505
gene id: 8090:LOC101166505
uniprot id: A0A3B3HP48
uniprot id: A0A3P9LGX9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

8090:p2ry4
gene id: 8090:p2ry4
uniprot id: H2L8P0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

8090:LOC101155494
gene id: 8090:LOC101155494
uniprot id: A0A3B3I1T6
names: Subcellular Location Annotation
messages: Cytoplasm

8090:LOC101167438
gene id: 8090:LOC101167438
uniprot id: H2N2N8
names: Subcellular Location Annotation
messages: Membrane

8090:acta2
gene id: 8090:acta2
uniprot id: A0A3B3HUH6
uniprot id: A0A3P9KIR7
names: Similarity
messages: Belongs to the actin family.

8090:LOC101174288
gene id: 8090:LOC101174288
uniprot id: H2L6Y0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

8090:LOC101155367
gene id: 8090:LOC101155367
uniprot id: A0A3P9KUL3
uniprot id: H2LBE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

8090:vbp1
gene id: 8090:vbp1
uniprot id: A0A3P9JTH2
uniprot id: H2LWI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

8090:dscc1
gene id: 8090:dscc1
uniprot id: H2LIN2
names: Similarity
messages: Belongs to the DCC1 family.

8090:LOC101165832
gene id: 8090:LOC101165832
uniprot id: H2M476
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

8090:lyrm1
gene id: 8090:lyrm1
uniprot id: A0A3B3I6S1
names: Similarity
messages: Belongs to the complex I LYR family.

8090:LOC101156110
gene id: 8090:LOC101156110
uniprot id: A0A3B3H7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

8090:recql
gene id: 8090:recql
uniprot id: A0A3B3IC83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

8090:arf1
gene id: 8090:arf1
uniprot id: A0A3P9HH08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

8090:rab38
gene id: 8090:rab38
uniprot id: A0A3P9GXA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

8090:adcy9
gene id: 8090:adcy9
uniprot id: A0A3B3H7E7
uniprot id: A0A3B3HE73
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

8090:thrap3
gene id: 8090:thrap3
uniprot id: H2M0N9
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

8090:LOC101160655
gene id: 8090:LOC101160655
uniprot id: A0A3B3HSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

8090:recql5
gene id: 8090:recql5
uniprot id: H2MA39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus