797303:NATPE RS07155
gene id: 797303:NATPE_RS07155
uniprot id: L0JJD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797303:NATPE RS13115
gene id: 797303:NATPE_RS13115
uniprot id: L0JP08
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

797303:NATPE RS07945
gene id: 797303:NATPE_RS07945
uniprot id: L0JLT9
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

797303:NATPE RS17790
gene id: 797303:NATPE_RS17790
uniprot id: L9YAS7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS05300
gene id: 797303:NATPE_RS05300
uniprot id: L0JJJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

797303:NATPE RS20450
gene id: 797303:NATPE_RS20450
uniprot id: L9Y6D9
names: Caution
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11220
gene id: 797303:NATPE_RS11220
uniprot id: L0JNM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

797303:NATPE RS05655
gene id: 797303:NATPE_RS05655
uniprot id: L0JKH1
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

797303:NATPE RS10210
gene id: 797303:NATPE_RS10210
uniprot id: L0JN40
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS14800
gene id: 797303:NATPE_RS14800
uniprot id: L0JRC4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

797303:NATPE RS08480
gene id: 797303:NATPE_RS08480
uniprot id: L0JM42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797303:NATPE RS15955
gene id: 797303:NATPE_RS15955
uniprot id: L9YCL6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS09165
gene id: 797303:NATPE_RS09165
uniprot id: L0JLU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS06480
gene id: 797303:NATPE_RS06480
uniprot id: L0JLM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS07005
gene id: 797303:NATPE_RS07005
uniprot id: L0JKJ8
names: Subcellular Location Annotation
messages: Cytoplasm

797303:NATPE RS16815
gene id: 797303:NATPE_RS16815
uniprot id: L0JQ39
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS01330
gene id: 797303:NATPE_RS01330
uniprot id: L0JFX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

797303:NATPE RS10095
gene id: 797303:NATPE_RS10095
uniprot id: L0JN24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

797303:NATPE RS07645
gene id: 797303:NATPE_RS07645
uniprot id: L0JLN4
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS12475
gene id: 797303:NATPE_RS12475
uniprot id: L0JNP8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS15105
gene id: 797303:NATPE_RS15105
uniprot id: L0JQ80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

797303:NATPE RS11710
gene id: 797303:NATPE_RS11710
uniprot id: L0JPL7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797303:NATPE RS12760
gene id: 797303:NATPE_RS12760
uniprot id: L0JQ51
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

797303:NATPE RS20680
gene id: 797303:NATPE_RS20680
uniprot id: L0JTZ4
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

797303:NATPE RS01460
gene id: 797303:NATPE_RS01460
uniprot id: L9YYL5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS05435
gene id: 797303:NATPE_RS05435
uniprot id: L0JKC3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS03275
gene id: 797303:NATPE_RS03275
uniprot id: L0JIB7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

797303:NATPE RS14890
gene id: 797303:NATPE_RS14890
uniprot id: L0JRE0
names: Similarity
messages: Belongs to the Dps family.

797303:NATPE RS11460
gene id: 797303:NATPE_RS11460
uniprot id: L0JL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

797303:NATPE RS03335
gene id: 797303:NATPE_RS03335
uniprot id: L0JJS7
names: Similarity
messages: Belongs to the HypE family.

797303:NATPE RS07265
gene id: 797303:NATPE_RS07265
uniprot id: L0JM22
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

797303:NATPE RS13535
gene id: 797303:NATPE_RS13535
uniprot id: L0JQL1
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

797303:NATPE RS00380
gene id: 797303:NATPE_RS00380
uniprot id: L0JGP9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797303:NATPE RS10760
gene id: 797303:NATPE_RS10760
uniprot id: L9YSC3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS12365
gene id: 797303:NATPE_RS12365
uniprot id: L0JPX9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

797303:NATPE RS11050
gene id: 797303:NATPE_RS11050
uniprot id: L0JMU6
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS11645
gene id: 797303:NATPE_RS11645
uniprot id: L0JLA9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

797303:NATPE RS18060
gene id: 797303:NATPE_RS18060
uniprot id: L0JT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797303:NATPE RS17455
gene id: 797303:NATPE_RS17455
uniprot id: L0JS40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS13880
gene id: 797303:NATPE_RS13880
uniprot id: L0JMI0
names: Similarity
messages: Belongs to the peptidase M24B family.

797303:NATPE RS15620
gene id: 797303:NATPE_RS15620
uniprot id: L0JQI8
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

797303:NATPE RS08125
gene id: 797303:NATPE_RS08125
uniprot id: L0JMI7
names: Function
messages: Part of a potassium transport system.

797303:NATPE RS09905
gene id: 797303:NATPE_RS09905
uniprot id: L0JM81
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797303:NATPE RS09570
gene id: 797303:NATPE_RS09570
uniprot id: L0JMS4
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS06825
gene id: 797303:NATPE_RS06825
uniprot id: L0JL88
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

797303:NATPE RS06965
gene id: 797303:NATPE_RS06965
uniprot id: L0JIL4
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS14160
gene id: 797303:NATPE_RS14160
uniprot id: L0JQC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS16675
gene id: 797303:NATPE_RS16675
uniprot id: L0JP62
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

797303:NATPE RS01980
gene id: 797303:NATPE_RS01980
uniprot id: L0JJ38
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

797303:NATPE RS06710
gene id: 797303:NATPE_RS06710
uniprot id: L9Z754
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS06465
gene id: 797303:NATPE_RS06465
uniprot id: L0JK79
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS16800
gene id: 797303:NATPE_RS16800
uniprot id: L9YCA3
names: Caution
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS09945
gene id: 797303:NATPE_RS09945
uniprot id: L0JMZ7
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

797303:NATPE RS04380
gene id: 797303:NATPE_RS04380
uniprot id: L0JJ12
names: Similarity
messages: Belongs to the peptidase S8 family.

797303:NATPE RS00785
gene id: 797303:NATPE_RS00785
uniprot id: L0JID6
names: Similarity
messages: Belongs to the SUI1 family.

797303:NATPE RS07745
gene id: 797303:NATPE_RS07745
uniprot id: L0JJQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

797303:NATPE RS08285
gene id: 797303:NATPE_RS08285
uniprot id: L9YHL4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14770
gene id: 797303:NATPE_RS14770
uniprot id: L0JN26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

797303:NATPE RS03430
gene id: 797303:NATPE_RS03430
uniprot id: L0JJU2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

797303:NATPE RS19850
gene id: 797303:NATPE_RS19850
uniprot id: L9Y657
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS07800
gene id: 797303:NATPE_RS07800
uniprot id: L0JMC7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

797303:NATPE RS02895
gene id: 797303:NATPE_RS02895
uniprot id: L0JIW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

797303:NATPE RS01315
gene id: 797303:NATPE_RS01315
uniprot id: L0JIP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

797303:NATPE RS06345
gene id: 797303:NATPE_RS06345
uniprot id: L0JK53
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

797303:NATPE RS14685
gene id: 797303:NATPE_RS14685
uniprot id: L0JQ00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

797303:NATPE RS17520
gene id: 797303:NATPE_RS17520
uniprot id: L9YAQ2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS06530
gene id: 797303:NATPE_RS06530
uniprot id: L0JIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS05890
gene id: 797303:NATPE_RS05890
uniprot id: L0JII0
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

797303:NATPE RS12290
gene id: 797303:NATPE_RS12290
uniprot id: L0JPW9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

797303:NATPE RS00190
gene id: 797303:NATPE_RS00190
uniprot id: L0JI31
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

797303:NATPE RS01660
gene id: 797303:NATPE_RS01660
uniprot id: L0JIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane

797303:NATPE RS16145
gene id: 797303:NATPE_RS16145
uniprot id: L0JPN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.

797303:NATPE RS13975
gene id: 797303:NATPE_RS13975
uniprot id: L0JNC0
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

797303:NATPE RS20110
gene id: 797303:NATPE_RS20110
uniprot id: L0JR45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797303:NATPE RS19095
gene id: 797303:NATPE_RS19095
uniprot id: L9Y2V5
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS16325
gene id: 797303:NATPE_RS16325
uniprot id: L0JPR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

797303:NATPE RS15740
gene id: 797303:NATPE_RS15740
uniprot id: L0JPF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

797303:NATPE RS15945
gene id: 797303:NATPE_RS15945
uniprot id: L0JR97
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797303:NATPE RS09020
gene id: 797303:NATPE_RS09020
uniprot id: L0JKG3
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

797303:NATPE RS06765
gene id: 797303:NATPE_RS06765
uniprot id: L0JKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797303:NATPE RS01640
gene id: 797303:NATPE_RS01640
uniprot id: L0JI91
names: Similarity
messages: Belongs to the NAD synthetase family.

797303:NATPE RS04120
gene id: 797303:NATPE_RS04120
uniprot id: L0JK87
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797303:NATPE RS03295
gene id: 797303:NATPE_RS03295
uniprot id: L0JJ34
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

797303:NATPE RS11070
gene id: 797303:NATPE_RS11070
uniprot id: L0JNJ5
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

797303:NATPE RS12155
gene id: 797303:NATPE_RS12155
uniprot id: L0JMA8
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

797303:NATPE RS05760
gene id: 797303:NATPE_RS05760
uniprot id: L0JKJ1
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS14120
gene id: 797303:NATPE_RS14120
uniprot id: L0JMQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

797303:NATPE RS13050
gene id: 797303:NATPE_RS13050
uniprot id: L0JM04
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

797303:NATPE RS02345
gene id: 797303:NATPE_RS02345
uniprot id: L0JIM7
names: Similarity
messages: Belongs to the peptidase S9C family.

797303:NATPE RS09670
gene id: 797303:NATPE_RS09670
uniprot id: L0JM35
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

797303:NATPE RS13965
gene id: 797303:NATPE_RS13965
uniprot id: L0JQ63
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

797303:NATPE RS04330
gene id: 797303:NATPE_RS04330
uniprot id: L0JJ02
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

797303:NATPE RS06925
gene id: 797303:NATPE_RS06925
uniprot id: L0JLA0
names: Similarity
messages: Belongs to the UPF0173 family.

797303:NATPE RS17145
gene id: 797303:NATPE_RS17145
uniprot id: L0JRZ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797303:NATPE RS00955
gene id: 797303:NATPE_RS00955
uniprot id: L0JFQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

797303:NATPE RS11290
gene id: 797303:NATPE_RS11290
uniprot id: L0JPD3
names: Similarity
messages: Belongs to the BtpA family.

797303:NATPE RS02680
gene id: 797303:NATPE_RS02680
uniprot id: L0JGQ0
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS08200
gene id: 797303:NATPE_RS08200
uniprot id: L0JJZ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

797303:NATPE RS02245
gene id: 797303:NATPE_RS02245
uniprot id: L0JGH5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

797303:NATPE RS10780
gene id: 797303:NATPE_RS10780
uniprot id: L0JKP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS15360
gene id: 797303:NATPE_RS15360
uniprot id: L0JNC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

797303:NATPE RS04525
gene id: 797303:NATPE_RS04525
uniprot id: L0JKH0
names: Similarity
messages: Belongs to the HypE family.

797303:NATPE RS01865
gene id: 797303:NATPE_RS01865
uniprot id: L9YY44
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS16055
gene id: 797303:NATPE_RS16055
uniprot id: L9YFX8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04770
gene id: 797303:NATPE_RS04770
uniprot id: L0JJZ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS00975
gene id: 797303:NATPE_RS00975
uniprot id: L0JH01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

797303:NATPE RS08620
gene id: 797303:NATPE_RS08620
uniprot id: L9YGS4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS00830
gene id: 797303:NATPE_RS00830
uniprot id: L0JEZ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS08060
gene id: 797303:NATPE_RS08060
uniprot id: L0JL47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797303:NATPE RS04185
gene id: 797303:NATPE_RS04185
uniprot id: L0JGX1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

797303:NATPE RS00480
gene id: 797303:NATPE_RS00480
uniprot id: L9YBA2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14275
gene id: 797303:NATPE_RS14275
uniprot id: L0JR41
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

797303:NATPE RS05880
gene id: 797303:NATPE_RS05880
uniprot id: L0JKL3
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

797303:NATPE RS03875
gene id: 797303:NATPE_RS03875
uniprot id: L9Z583
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS15850
gene id: 797303:NATPE_RS15850
uniprot id: L0JRY3
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

797303:NATPE RS05080
gene id: 797303:NATPE_RS05080
uniprot id: L0JI33
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS05195
gene id: 797303:NATPE_RS05195
uniprot id: L0JJH1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS15580
gene id: 797303:NATPE_RS15580
uniprot id: L0JNG6
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS11670
gene id: 797303:NATPE_RS11670
uniprot id: L0JLB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS07490
gene id: 797303:NATPE_RS07490
uniprot id: L0JIV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

797303:NATPE RS14115
gene id: 797303:NATPE_RS14115
uniprot id: L0JNH5
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

797303:NATPE RS18160
gene id: 797303:NATPE_RS18160
uniprot id: L0JQR9
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

797303:NATPE RS06685
gene id: 797303:NATPE_RS06685
uniprot id: L9Z758
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11850
gene id: 797303:NATPE_RS11850
uniprot id: L0JPQ0
names: Similarity
messages: Belongs to the SDO1/SBDS family.

797303:NATPE RS00870
gene id: 797303:NATPE_RS00870
uniprot id: L9Y7Y6
names: Caution
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04390
gene id: 797303:NATPE_RS04390
uniprot id: L0JH34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

797303:NATPE RS10785
gene id: 797303:NATPE_RS10785
uniprot id: L0JP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

797303:NATPE RS14560
gene id: 797303:NATPE_RS14560
uniprot id: L0JPX7
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

797303:NATPE RS09560
gene id: 797303:NATPE_RS09560
uniprot id: L0JK23
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797303:NATPE RS12220
gene id: 797303:NATPE_RS12220
uniprot id: L0JPW1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS15970
gene id: 797303:NATPE_RS15970
uniprot id: L9YDN4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS18720
gene id: 797303:NATPE_RS18720
uniprot id: L0JSA7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

797303:NATPE RS00040
gene id: 797303:NATPE_RS00040
uniprot id: L0JF88
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

797303:NATPE RS20265
gene id: 797303:NATPE_RS20265
uniprot id: L0JS04
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS08105
gene id: 797303:NATPE_RS08105
uniprot id: L0JLW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

797303:NATPE RS01075
gene id: 797303:NATPE_RS01075
uniprot id: L0JH24
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

797303:NATPE RS18230
gene id: 797303:NATPE_RS18230
uniprot id: L0JQT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

797303:NATPE RS06075
gene id: 797303:NATPE_RS06075
uniprot id: L9Z8I1
names: Similarity
messages: Belongs to the SCO1/2 family.

797303:NATPE RS18870
gene id: 797303:NATPE_RS18870
uniprot id: L9YR27
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS20590
gene id: 797303:NATPE_RS20590
uniprot id: L9YDN3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04955
gene id: 797303:NATPE_RS04955
uniprot id: L9Z662
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS12410
gene id: 797303:NATPE_RS12410
uniprot id: L0JLP1
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS17130
gene id: 797303:NATPE_RS17130
uniprot id: L0JPD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

797303:NATPE RS05525
gene id: 797303:NATPE_RS05525
uniprot id: L9Z7E7
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS03805
gene id: 797303:NATPE_RS03805
uniprot id: L0JHA8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797303:NATPE RS17875
gene id: 797303:NATPE_RS17875
uniprot id: L0JRS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

797303:NATPE RS01795
gene id: 797303:NATPE_RS01795
uniprot id: L0JG95
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

797303:NATPE RS17565
gene id: 797303:NATPE_RS17565
uniprot id: L0JPM0
names: Subcellular Location Annotation
messages: Cytoplasm

797303:NATPE RS08615
gene id: 797303:NATPE_RS08615
uniprot id: L0JJH4
names: Function
messages: Part of a potassium transport system.

797303:NATPE RS04360
gene id: 797303:NATPE_RS04360
uniprot id: L0JHP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

797303:NATPE RS08045
gene id: 797303:NATPE_RS08045
uniprot id: L0JJ52
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

797303:NATPE RS07165
gene id: 797303:NATPE_RS07165
uniprot id: L0JM05
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

797303:NATPE RS09550
gene id: 797303:NATPE_RS09550
uniprot id: L9YU98
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS09620
gene id: 797303:NATPE_RS09620
uniprot id: L0JMT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

797303:NATPE RS17685
gene id: 797303:NATPE_RS17685
uniprot id: L0JRP2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS14195
gene id: 797303:NATPE_RS14195
uniprot id: L0JNI9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS04610
gene id: 797303:NATPE_RS04610
uniprot id: L0JH72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

797303:NATPE RS13825
gene id: 797303:NATPE_RS13825
uniprot id: L0JMH0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

797303:NATPE RS15200
gene id: 797303:NATPE_RS15200
uniprot id: L0JQV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS08425
gene id: 797303:NATPE_RS08425
uniprot id: L0JM30
names: Similarity
messages: Belongs to the arginase family.

797303:NATPE RS03920
gene id: 797303:NATPE_RS03920
uniprot id: L0JJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

797303:NATPE RS04915
gene id: 797303:NATPE_RS04915
uniprot id: L0JHC6
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS09910
gene id: 797303:NATPE_RS09910
uniprot id: L0JL02
names: Similarity
messages: Belongs to the AOR/FOR family.

797303:NATPE RS03410
gene id: 797303:NATPE_RS03410
uniprot id: L0JJT7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

797303:NATPE RS14635
gene id: 797303:NATPE_RS14635
uniprot id: L0JNR9
names: Similarity
messages: Belongs to the PspA/IM30 family.

797303:NATPE RS06160
gene id: 797303:NATPE_RS06160
uniprot id: L0JLE8
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797303:NATPE RS19720
gene id: 797303:NATPE_RS19720
uniprot id: L0JU40
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS06415
gene id: 797303:NATPE_RS06415
uniprot id: L0JK68
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

797303:NATPE RS00005
gene id: 797303:NATPE_RS00005
uniprot id: L0JHB6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS03705
gene id: 797303:NATPE_RS03705
uniprot id: L9Z3S5
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04965
gene id: 797303:NATPE_RS04965
uniprot id: L0JHD5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS14750
gene id: 797303:NATPE_RS14750
uniprot id: L0JRB4
names: Similarity
messages: Belongs to the thymidylate kinase family.

797303:NATPE RS04760
gene id: 797303:NATPE_RS04760
uniprot id: L0JH96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

797303:NATPE RS15765
gene id: 797303:NATPE_RS15765
uniprot id: L0JPF4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

797303:NATPE RS08450
gene id: 797303:NATPE_RS08450
uniprot id: L0JMP6
names: Similarity
messages: Belongs to the TPP enzyme family.

797303:NATPE RS20730
gene id: 797303:NATPE_RS20730
uniprot id: L0JRG2
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

797303:NATPE RS13945
gene id: 797303:NATPE_RS13945
uniprot id: L0JPH5
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS10795
gene id: 797303:NATPE_RS10795
uniprot id: L0JMP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

797303:NATPE RS07785
gene id: 797303:NATPE_RS07785
uniprot id: L0JLQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Cytoplasm
messages: Gas vesicle
messages: Vesicle

797303:NATPE RS02805
gene id: 797303:NATPE_RS02805
uniprot id: L0JI30
names: Similarity
messages: Belongs to the Ahb/Nir family.

797303:NATPE RS02885
gene id: 797303:NATPE_RS02885
uniprot id: L0JG51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

797303:NATPE RS00685
gene id: 797303:NATPE_RS00685
uniprot id: L0JIB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

797303:NATPE RS11325
gene id: 797303:NATPE_RS11325
uniprot id: L0JL19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

797303:NATPE RS03225
gene id: 797303:NATPE_RS03225
uniprot id: L0JGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

797303:NATPE RS03840
gene id: 797303:NATPE_RS03840
uniprot id: L0JK24
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

797303:NATPE RS17740
gene id: 797303:NATPE_RS17740
uniprot id: L0JQI7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

797303:NATPE RS02950
gene id: 797303:NATPE_RS02950
uniprot id: L0JIX6
names: Subcellular Location Annotation
messages: Cytoplasm

797303:NATPE RS04885
gene id: 797303:NATPE_RS04885
uniprot id: L0JHZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

797303:NATPE RS16610
gene id: 797303:NATPE_RS16610
uniprot id: L0JR66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

797303:NATPE RS09690
gene id: 797303:NATPE_RS09690
uniprot id: L0JMU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

797303:NATPE RS17965
gene id: 797303:NATPE_RS17965
uniprot id: L0JT35
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.

797303:NATPE RS19375
gene id: 797303:NATPE_RS19375
uniprot id: L0JTA3
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS17940
gene id: 797303:NATPE_RS17940
uniprot id: L0JT30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P(II) protein family.
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

797303:NATPE RS20780
gene id: 797303:NATPE_RS20780
uniprot id: L0JTI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS14410
gene id: 797303:NATPE_RS14410
uniprot id: L0JPU2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

797303:NATPE RS09740
gene id: 797303:NATPE_RS09740
uniprot id: L0JK57
names: Similarity
messages: Belongs to the Nth/MutY family.

797303:NATPE RS06060
gene id: 797303:NATPE_RS06060
uniprot id: L0JJZ0
names: Similarity
messages: Belongs to the peptidase M24B family.

797303:NATPE RS09935
gene id: 797303:NATPE_RS09935
uniprot id: L0JL06
names: Similarity
messages: Belongs to the peptidase C56 family.

797303:NATPE RS13910
gene id: 797303:NATPE_RS13910
uniprot id: L0JQU4
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS14490
gene id: 797303:NATPE_RS14490
uniprot id: L0JNP6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

797303:NATPE RS20870
gene id: 797303:NATPE_RS20870
uniprot id: L0JUS8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

797303:NATPE RS15690
gene id: 797303:NATPE_RS15690
uniprot id: L0JPD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS07535
gene id: 797303:NATPE_RS07535
uniprot id: L0JJL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

797303:NATPE RS13970
gene id: 797303:NATPE_RS13970
uniprot id: L0JPI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797303:NATPE RS00260
gene id: 797303:NATPE_RS00260
uniprot id: L0JFC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

797303:NATPE RS17260
gene id: 797303:NATPE_RS17260
uniprot id: L0JRG8
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

797303:NATPE RS02335
gene id: 797303:NATPE_RS02335
uniprot id: L0JFW2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS07805
gene id: 797303:NATPE_RS07805
uniprot id: L0JL03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

797303:NATPE RS19405
gene id: 797303:NATPE_RS19405
uniprot id: L0JTA9
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS07115
gene id: 797303:NATPE_RS07115
uniprot id: L0JIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS20470
gene id: 797303:NATPE_RS20470
uniprot id: L0JUJ1
names: Similarity
messages: Belongs to the peptidase S9C family.

797303:NATPE RS00515
gene id: 797303:NATPE_RS00515
uniprot id: L0JGS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

797303:NATPE RS14185
gene id: 797303:NATPE_RS14185
uniprot id: L0JQC6
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

797303:NATPE RS18085
gene id: 797303:NATPE_RS18085
uniprot id: L0JQQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

797303:NATPE RS00230
gene id: 797303:NATPE_RS00230
uniprot id: L9Y9C2
names: Caution
names: Similarity
messages: Belongs to the IMPACT family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS01255
gene id: 797303:NATPE_RS01255
uniprot id: L0JH57
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

797303:NATPE RS12865
gene id: 797303:NATPE_RS12865
uniprot id: L0JQ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

797303:NATPE RS07305
gene id: 797303:NATPE_RS07305
uniprot id: L0JJH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

797303:NATPE RS03815
gene id: 797303:NATPE_RS03815
uniprot id: L0JK19
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

797303:NATPE RS03675
gene id: 797303:NATPE_RS03675
uniprot id: L0JIJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

797303:NATPE RS14430
gene id: 797303:NATPE_RS14430
uniprot id: L0JQH3
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS08020
gene id: 797303:NATPE_RS08020
uniprot id: L0JMG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

797303:NATPE RS01250
gene id: 797303:NATPE_RS01250
uniprot id: L0JHZ8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

797303:NATPE RS04995
gene id: 797303:NATPE_RS04995
uniprot id: L0JKQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS00275
gene id: 797303:NATPE_RS00275
uniprot id: L0JI44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797303:NATPE RS17840
gene id: 797303:NATPE_RS17840
uniprot id: L0JT15
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS18665
gene id: 797303:NATPE_RS18665
uniprot id: L9YSU9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS02240
gene id: 797303:NATPE_RS02240
uniprot id: L0JHS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

797303:NATPE RS13915
gene id: 797303:NATPE_RS13915
uniprot id: L0JQ53
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

797303:NATPE RS18055
gene id: 797303:NATPE_RS18055
uniprot id: L0JPW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS19695
gene id: 797303:NATPE_RS19695
uniprot id: L9Y6P7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS02275
gene id: 797303:NATPE_RS02275
uniprot id: L0JFV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

797303:NATPE RS17270
gene id: 797303:NATPE_RS17270
uniprot id: L0JPG8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

797303:NATPE RS03785
gene id: 797303:NATPE_RS03785
uniprot id: L0JGN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-archaeol synthase family.
messages: Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
messages: Cell membrane

797303:NATPE RS06955
gene id: 797303:NATPE_RS06955
uniprot id: L0JKI9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS20770
gene id: 797303:NATPE_RS20770
uniprot id: L0JRH3
names: Similarity
messages: Belongs to the IMPACT family.

797303:NATPE RS07295
gene id: 797303:NATPE_RS07295
uniprot id: L0JLG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

797303:NATPE RS12550
gene id: 797303:NATPE_RS12550
uniprot id: L0JNR2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

797303:NATPE RS08845
gene id: 797303:NATPE_RS08845
uniprot id: L0JMC8
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS16395
gene id: 797303:NATPE_RS16395
uniprot id: L0JNY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

797303:NATPE RS08030
gene id: 797303:NATPE_RS08030
uniprot id: L0JL42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS16590
gene id: 797303:NATPE_RS16590
uniprot id: L0JPY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS20675
gene id: 797303:NATPE_RS20675
uniprot id: L0JUN5
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05190
gene id: 797303:NATPE_RS05190
uniprot id: L0JKU6
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

797303:NATPE RS13865
gene id: 797303:NATPE_RS13865
uniprot id: L0JQ43
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

797303:NATPE RS03835
gene id: 797303:NATPE_RS03835
uniprot id: L0JGP8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797303:NATPE RS17595
gene id: 797303:NATPE_RS17595
uniprot id: L0JPM5
names: Similarity
messages: Belongs to the UPF0201 family.

797303:NATPE RS01780
gene id: 797303:NATPE_RS01780
uniprot id: L0JJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797303:NATPE RS05230
gene id: 797303:NATPE_RS05230
uniprot id: L0JK84
names: Subcellular Location Annotation
messages: Cell membrane

797303:NATPE RS00890
gene id: 797303:NATPE_RS00890
uniprot id: L0JHS4
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS04550
gene id: 797303:NATPE_RS04550
uniprot id: L0JKH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

797303:NATPE RS01470
gene id: 797303:NATPE_RS01470
uniprot id: L0JHA5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

797303:NATPE RS16360
gene id: 797303:NATPE_RS16360
uniprot id: L0JS80
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

797303:NATPE RS12070
gene id: 797303:NATPE_RS12070
uniprot id: L0JNG3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS14050
gene id: 797303:NATPE_RS14050
uniprot id: L0JML6
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS10565
gene id: 797303:NATPE_RS10565
uniprot id: L0JNA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

797303:NATPE RS04190
gene id: 797303:NATPE_RS04190
uniprot id: L0JKA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

797303:NATPE RS12905
gene id: 797303:NATPE_RS12905
uniprot id: L0JLX5
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

797303:NATPE RS18190
gene id: 797303:NATPE_RS18190
uniprot id: L0JPZ0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

797303:NATPE RS17045
gene id: 797303:NATPE_RS17045
uniprot id: L0JRX8
names: Function
messages: Part of a potassium transport system.

797303:NATPE RS18155
gene id: 797303:NATPE_RS18155
uniprot id: L0JRY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

797303:NATPE RS02005
gene id: 797303:NATPE_RS02005
uniprot id: L9YYT6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS20145
gene id: 797303:NATPE_RS20145
uniprot id: L0JTP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797303:NATPE RS10030
gene id: 797303:NATPE_RS10030
uniprot id: L0JL24
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797303:NATPE RS05450
gene id: 797303:NATPE_RS05450
uniprot id: L0JL07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

797303:NATPE RS16670
gene id: 797303:NATPE_RS16670
uniprot id: L0JQ11
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS00945
gene id: 797303:NATPE_RS00945
uniprot id: L0JHT7
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

797303:NATPE RS17085
gene id: 797303:NATPE_RS17085
uniprot id: L0JPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

797303:NATPE RS00665
gene id: 797303:NATPE_RS00665
uniprot id: L0JHM3
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS01655
gene id: 797303:NATPE_RS01655
uniprot id: L0JFG7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS04755
gene id: 797303:NATPE_RS04755
uniprot id: L0JHX0
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

797303:NATPE RS06975
gene id: 797303:NATPE_RS06975
uniprot id: L0JLA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS14065
gene id: 797303:NATPE_RS14065
uniprot id: L0JPK8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS06180
gene id: 797303:NATPE_RS06180
uniprot id: L9Z6A4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17860
gene id: 797303:NATPE_RS17860
uniprot id: L0JPS9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

797303:NATPE RS08985
gene id: 797303:NATPE_RS08985
uniprot id: L0JMF5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS00255
gene id: 797303:NATPE_RS00255
uniprot id: L9Y9C7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11315
gene id: 797303:NATPE_RS11315
uniprot id: L0JN04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

797303:NATPE RS08445
gene id: 797303:NATPE_RS08445
uniprot id: L0JJD6
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS13130
gene id: 797303:NATPE_RS13130
uniprot id: L0JQC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

797303:NATPE RS12085
gene id: 797303:NATPE_RS12085
uniprot id: L0JM94
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS10445
gene id: 797303:NATPE_RS10445
uniprot id: L0JNW1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

797303:NATPE RS08520
gene id: 797303:NATPE_RS08520
uniprot id: L0JJF4
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS12400
gene id: 797303:NATPE_RS12400
uniprot id: L0JNN7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS00395
gene id: 797303:NATPE_RS00395
uniprot id: L0JI69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

797303:NATPE RS09940
gene id: 797303:NATPE_RS09940
uniprot id: L0JK93
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

797303:NATPE RS05310
gene id: 797303:NATPE_RS05310
uniprot id: L9Z444
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS01265
gene id: 797303:NATPE_RS01265
uniprot id: L0JIN5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797303:NATPE RS15560
gene id: 797303:NATPE_RS15560
uniprot id: L0JRR5
names: Similarity
messages: Belongs to the TrpC family.

797303:NATPE RS19500
gene id: 797303:NATPE_RS19500
uniprot id: L0JRL0
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS06335
gene id: 797303:NATPE_RS06335
uniprot id: L0JLI8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

797303:NATPE RS08025
gene id: 797303:NATPE_RS08025
uniprot id: L0JLV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

797303:NATPE RS13770
gene id: 797303:NATPE_RS13770
uniprot id: L0JN75
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS05455
gene id: 797303:NATPE_RS05455
uniprot id: L0JKD0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797303:NATPE RS04405
gene id: 797303:NATPE_RS04405
uniprot id: L0JJ17
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

797303:NATPE RS19530
gene id: 797303:NATPE_RS19530
uniprot id: L9YSZ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS15815
gene id: 797303:NATPE_RS15815
uniprot id: L9YFS4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11760
gene id: 797303:NATPE_RS11760
uniprot id: L0JPM6
names: Similarity
messages: Belongs to the GARS family.

797303:NATPE RS16560
gene id: 797303:NATPE_RS16560
uniprot id: L0JR32
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797303:NATPE RS20595
gene id: 797303:NATPE_RS20595
uniprot id: L9YEQ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS16780
gene id: 797303:NATPE_RS16780
uniprot id: L0JRT9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS05135
gene id: 797303:NATPE_RS05135
uniprot id: L0JHG2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

797303:NATPE RS13670
gene id: 797303:NATPE_RS13670
uniprot id: L0JN57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

797303:NATPE RS02250
gene id: 797303:NATPE_RS02250
uniprot id: L0JFU9
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus

797303:NATPE RS03450
gene id: 797303:NATPE_RS03450
uniprot id: L0JH41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS01755
gene id: 797303:NATPE_RS01755
uniprot id: L0JFL5
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797303:NATPE RS06155
gene id: 797303:NATPE_RS06155
uniprot id: L0JIP0
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

797303:NATPE RS17820
gene id: 797303:NATPE_RS17820
uniprot id: L0JSA4
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

797303:NATPE RS04340
gene id: 797303:NATPE_RS04340
uniprot id: L0JH21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

797303:NATPE RS16340
gene id: 797303:NATPE_RS16340
uniprot id: L0JRI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

797303:NATPE RS12465
gene id: 797303:NATPE_RS12465
uniprot id: L0JPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

797303:NATPE RS13140
gene id: 797303:NATPE_RS13140
uniprot id: L0JP13
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

797303:NATPE RS13340
gene id: 797303:NATPE_RS13340
uniprot id: L0JPU4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

797303:NATPE RS08980
gene id: 797303:NATPE_RS08980
uniprot id: L0JN08
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

797303:NATPE RS14460
gene id: 797303:NATPE_RS14460
uniprot id: L0JPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

797303:NATPE RS10160
gene id: 797303:NATPE_RS10160
uniprot id: L9YV96
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS12215
gene id: 797303:NATPE_RS12215
uniprot id: L0JLK7
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

797303:NATPE RS17195
gene id: 797303:NATPE_RS17195
uniprot id: L0JS02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797303:NATPE RS14390
gene id: 797303:NATPE_RS14390
uniprot id: L0JNM8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

797303:NATPE RS01810
gene id: 797303:NATPE_RS01810
uniprot id: L0JID8
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797303:NATPE RS07925
gene id: 797303:NATPE_RS07925
uniprot id: L0JL26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

797303:NATPE RS11065
gene id: 797303:NATPE_RS11065
uniprot id: L0JP79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

797303:NATPE RS01885
gene id: 797303:NATPE_RS01885
uniprot id: L0JFN5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

797303:NATPE RS01435
gene id: 797303:NATPE_RS01435
uniprot id: L0JI43
names: Similarity
messages: Belongs to the peptidase C59 family.

797303:NATPE RS08225
gene id: 797303:NATPE_RS08225
uniprot id: L0JK03
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

797303:NATPE RS07255
gene id: 797303:NATPE_RS07255
uniprot id: L0JJG2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

797303:NATPE RS19485
gene id: 797303:NATPE_RS19485
uniprot id: L0JU07
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

797303:NATPE RS18630
gene id: 797303:NATPE_RS18630
uniprot id: L0JTG7
names: Similarity
messages: Belongs to the MCM family.

797303:NATPE RS16810
gene id: 797303:NATPE_RS16810
uniprot id: L0JRA2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS02700
gene id: 797303:NATPE_RS02700
uniprot id: L0JI13
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS20460
gene id: 797303:NATPE_RS20460
uniprot id: L0JRA8
names: Similarity
messages: Belongs to the PEPCase type 1 family.

797303:NATPE RS07365
gene id: 797303:NATPE_RS07365
uniprot id: L0JJI2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS13325
gene id: 797303:NATPE_RS13325
uniprot id: L0JMY6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS10570
gene id: 797303:NATPE_RS10570
uniprot id: L0JMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

797303:NATPE RS05590
gene id: 797303:NATPE_RS05590
uniprot id: L0JIC9
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS13830
gene id: 797303:NATPE_RS13830
uniprot id: L0JQS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797303:NATPE RS14540
gene id: 797303:NATPE_RS14540
uniprot id: L0JNQ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

797303:NATPE RS05625
gene id: 797303:NATPE_RS05625
uniprot id: L0JL40
names: Similarity
messages: Belongs to the LarC family.

797303:NATPE RS07625
gene id: 797303:NATPE_RS07625
uniprot id: L9Z8C8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS07880
gene id: 797303:NATPE_RS07880
uniprot id: L0JJT2
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

797303:NATPE RS00680
gene id: 797303:NATPE_RS00680
uniprot id: L0JEW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

797303:NATPE RS04625
gene id: 797303:NATPE_RS04625
uniprot id: L0JJ55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS13690
gene id: 797303:NATPE_RS13690
uniprot id: L9YP59
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS20245
gene id: 797303:NATPE_RS20245
uniprot id: L9Y5L7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17250
gene id: 797303:NATPE_RS17250
uniprot id: L0JSR0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797303:NATPE RS15250
gene id: 797303:NATPE_RS15250
uniprot id: L0JQA6
names: Subunit
messages: Homodimer.

797303:NATPE RS01775
gene id: 797303:NATPE_RS01775
uniprot id: L0JFL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797303:NATPE RS08330
gene id: 797303:NATPE_RS08330
uniprot id: L0JMM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797303:NATPE RS17785
gene id: 797303:NATPE_RS17785
uniprot id: L9Y9J9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS06745
gene id: 797303:NATPE_RS06745
uniprot id: L0JJ45
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS13985
gene id: 797303:NATPE_RS13985
uniprot id: L0JQW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

797303:NATPE RS05470
gene id: 797303:NATPE_RS05470
uniprot id: L0JHM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

797303:NATPE RS09695
gene id: 797303:NATPE_RS09695
uniprot id: L0JKW2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS05910
gene id: 797303:NATPE_RS05910
uniprot id: L0JJW1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

797303:NATPE RS04205
gene id: 797303:NATPE_RS04205
uniprot id: L0JHK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

797303:NATPE RS15230
gene id: 797303:NATPE_RS15230
uniprot id: L0JQA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

797303:NATPE RS18330
gene id: 797303:NATPE_RS18330
uniprot id: L0JQV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS11085
gene id: 797303:NATPE_RS11085
uniprot id: L9YS37
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS08410
gene id: 797303:NATPE_RS08410
uniprot id: L0JK43
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS12530
gene id: 797303:NATPE_RS12530
uniprot id: L0JMH9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

797303:NATPE RS08885
gene id: 797303:NATPE_RS08885
uniprot id: L0JLL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

797303:NATPE RS17340
gene id: 797303:NATPE_RS17340
uniprot id: L0JQC0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS02860
gene id: 797303:NATPE_RS02860
uniprot id: L0JG47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797303:NATPE RS10110
gene id: 797303:NATPE_RS10110
uniprot id: L0JKC0
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

797303:NATPE RS04650
gene id: 797303:NATPE_RS04650
uniprot id: L0JJX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

797303:NATPE RS07575
gene id: 797303:NATPE_RS07575
uniprot id: L0JKV7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05345
gene id: 797303:NATPE_RS05345
uniprot id: L0JKA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

797303:NATPE RS19890
gene id: 797303:NATPE_RS19890
uniprot id: L9Y4X9
names: Caution
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS13310
gene id: 797303:NATPE_RS13310
uniprot id: L9YI25
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17420
gene id: 797303:NATPE_RS17420
uniprot id: L0JST4
names: Similarity
messages: Belongs to the threonine synthase family.

797303:NATPE RS04775
gene id: 797303:NATPE_RS04775
uniprot id: L0JJ85
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

797303:NATPE RS02540
gene id: 797303:NATPE_RS02540
uniprot id: L0JJD5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS12915
gene id: 797303:NATPE_RS12915
uniprot id: L9YHU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS15650
gene id: 797303:NATPE_RS15650
uniprot id: L9YCH8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS05530
gene id: 797303:NATPE_RS05530
uniprot id: L0JKE5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

797303:NATPE RS06780
gene id: 797303:NATPE_RS06780
uniprot id: L9Z7W9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS08190
gene id: 797303:NATPE_RS08190
uniprot id: L0JLY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

797303:NATPE RS02660
gene id: 797303:NATPE_RS02660
uniprot id: L0JG16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

797303:NATPE RS05810
gene id: 797303:NATPE_RS05810
uniprot id: L0JKK0
names: Similarity
messages: Belongs to the acylphosphatase family.

797303:NATPE RS03075
gene id: 797303:NATPE_RS03075
uniprot id: L0JI82
names: Function
messages: Part of a potassium transport system.

797303:NATPE RS16375
gene id: 797303:NATPE_RS16375
uniprot id: L0JPS0
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05905
gene id: 797303:NATPE_RS05905
uniprot id: L0JKL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

797303:NATPE RS14835
gene id: 797303:NATPE_RS14835
uniprot id: L0JNW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

797303:NATPE RS15380
gene id: 797303:NATPE_RS15380
uniprot id: L0JND3
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS18290
gene id: 797303:NATPE_RS18290
uniprot id: L0JTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797303:NATPE RS08205
gene id: 797303:NATPE_RS08205
uniprot id: L0JJ92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

797303:NATPE RS15930
gene id: 797303:NATPE_RS15930
uniprot id: L9YDM4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04425
gene id: 797303:NATPE_RS04425
uniprot id: L0JJS6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

797303:NATPE RS10665
gene id: 797303:NATPE_RS10665
uniprot id: L0JMM4
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

797303:NATPE RS07780
gene id: 797303:NATPE_RS07780
uniprot id: L0JMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

797303:NATPE RS03915
gene id: 797303:NATPE_RS03915
uniprot id: L0JK42
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS06640
gene id: 797303:NATPE_RS06640
uniprot id: L0JL44
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS11745
gene id: 797303:NATPE_RS11745
uniprot id: L0JNB1
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

797303:NATPE RS13015
gene id: 797303:NATPE_RS13015
uniprot id: L0JNY7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS14415
gene id: 797303:NATPE_RS14415
uniprot id: L9YNB6
names: Caution
names: Similarity
messages: Belongs to the complex I subunit 3 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS13495
gene id: 797303:NATPE_RS13495
uniprot id: L0JP80
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS15135
gene id: 797303:NATPE_RS15135
uniprot id: L0JP23
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

797303:NATPE RS03725
gene id: 797303:NATPE_RS03725
uniprot id: L0JK02
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS02665
gene id: 797303:NATPE_RS02665
uniprot id: L0JJF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

797303:NATPE RS13110
gene id: 797303:NATPE_RS13110
uniprot id: L0JPP0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

797303:NATPE RS11795
gene id: 797303:NATPE_RS11795
uniprot id: L0JM45
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS15205
gene id: 797303:NATPE_RS15205
uniprot id: L0JQ98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

797303:NATPE RS07525
gene id: 797303:NATPE_RS07525
uniprot id: L0JLL0
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05030
gene id: 797303:NATPE_RS05030
uniprot id: L9Z647
names: Caution
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11400
gene id: 797303:NATPE_RS11400
uniprot id: L0JNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

797303:NATPE RS07310
gene id: 797303:NATPE_RS07310
uniprot id: L0JIS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

797303:NATPE RS08770
gene id: 797303:NATPE_RS08770
uniprot id: L0JMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797303:NATPE RS14215
gene id: 797303:NATPE_RS14215
uniprot id: L0JPQ3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

797303:NATPE RS08215
gene id: 797303:NATPE_RS08215
uniprot id: L0JLZ0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

797303:NATPE RS07260
gene id: 797303:NATPE_RS07260
uniprot id: L0JIR6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

797303:NATPE RS12010
gene id: 797303:NATPE_RS12010
uniprot id: L0JPS2
names: Similarity
messages: Belongs to the UPF0047 family.

797303:NATPE RS11170
gene id: 797303:NATPE_RS11170
uniprot id: U3GLG1
names: Similarity
messages: Belongs to the SCO1/2 family.

797303:NATPE RS06820
gene id: 797303:NATPE_RS06820
uniprot id: L0JLU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

797303:NATPE RS16885
gene id: 797303:NATPE_RS16885
uniprot id: L0JSK2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797303:NATPE RS00960
gene id: 797303:NATPE_RS00960
uniprot id: L0JF23
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

797303:NATPE RS00020
gene id: 797303:NATPE_RS00020
uniprot id: L9Y8Y6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS05780
gene id: 797303:NATPE_RS05780
uniprot id: L0JL68
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797303:NATPE RS12580
gene id: 797303:NATPE_RS12580
uniprot id: L0JMI6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

797303:NATPE RS19425
gene id: 797303:NATPE_RS19425
uniprot id: L0JTZ9
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

797303:NATPE RS03365
gene id: 797303:NATPE_RS03365
uniprot id: L0JJ53
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS22660
gene id: 797303:NATPE_RS22660
uniprot id: L9YH72
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04845
gene id: 797303:NATPE_RS04845
uniprot id: L0JJA0
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS13235
gene id: 797303:NATPE_RS13235
uniprot id: L9YJ67
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11485
gene id: 797303:NATPE_RS11485
uniprot id: L0JL52
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

797303:NATPE RS00670
gene id: 797303:NATPE_RS00670
uniprot id: L0JGV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

797303:NATPE RS07995
gene id: 797303:NATPE_RS07995
uniprot id: L0JLU8
names: Similarity
messages: Belongs to the archease family.

797303:NATPE RS08090
gene id: 797303:NATPE_RS08090
uniprot id: L0JJX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797303:NATPE RS12620
gene id: 797303:NATPE_RS12620
uniprot id: L0JPF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797303:NATPE RS13165
gene id: 797303:NATPE_RS13165
uniprot id: L9YHZ5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS07775
gene id: 797303:NATPE_RS07775
uniprot id: L0JIZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

797303:NATPE RS01390
gene id: 797303:NATPE_RS01390
uniprot id: L9YWQ2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS07270
gene id: 797303:NATPE_RS07270
uniprot id: L0JLG1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

797303:NATPE RS12355
gene id: 797303:NATPE_RS12355
uniprot id: L0JME5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS04300
gene id: 797303:NATPE_RS04300
uniprot id: L0JJQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

797303:NATPE RS16260
gene id: 797303:NATPE_RS16260
uniprot id: L9YD76
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS07085
gene id: 797303:NATPE_RS07085
uniprot id: L0JJB6
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS11340
gene id: 797303:NATPE_RS11340
uniprot id: L0JN10
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

797303:NATPE RS00805
gene id: 797303:NATPE_RS00805
uniprot id: L0JEZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS03975
gene id: 797303:NATPE_RS03975
uniprot id: L0JK54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS16245
gene id: 797303:NATPE_RS16245
uniprot id: L0JRF5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

797303:NATPE RS04295
gene id: 797303:NATPE_RS04295
uniprot id: L0JKC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

797303:NATPE RS14420
gene id: 797303:NATPE_RS14420
uniprot id: L0JMW5
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

797303:NATPE RS05770
gene id: 797303:NATPE_RS05770
uniprot id: L0JIF7
names: Subcellular Location Annotation
messages: Cytoplasm

797303:NATPE RS00875
gene id: 797303:NATPE_RS00875
uniprot id: L0JFN9
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS09150
gene id: 797303:NATPE_RS09150
uniprot id: L0JJV3
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS08245
gene id: 797303:NATPE_RS08245
uniprot id: L9YJS5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11630
gene id: 797303:NATPE_RS11630
uniprot id: L0JNX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

797303:NATPE RS00030
gene id: 797303:NATPE_RS00030
uniprot id: L0JHC1
names: Similarity
messages: Belongs to the aspartokinase family.

797303:NATPE RS03950
gene id: 797303:NATPE_RS03950
uniprot id: L0JJG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

797303:NATPE RS07245
gene id: 797303:NATPE_RS07245
uniprot id: L9Z7X2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS08050
gene id: 797303:NATPE_RS08050
uniprot id: L0JMH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

797303:NATPE RS04250
gene id: 797303:NATPE_RS04250
uniprot id: L0JJP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

797303:NATPE RS10980
gene id: 797303:NATPE_RS10980
uniprot id: L0JKU2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS02795
gene id: 797303:NATPE_RS02795
uniprot id: L0JJI1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

797303:NATPE RS14480
gene id: 797303:NATPE_RS14480
uniprot id: L0JQI2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

797303:NATPE RS00600
gene id: 797303:NATPE_RS00600
uniprot id: L0JFI3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

797303:NATPE RS01215
gene id: 797303:NATPE_RS01215
uniprot id: L0JF73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.
messages: Cytoplasm

797303:NATPE RS16725
gene id: 797303:NATPE_RS16725
uniprot id: L0JRT2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

797303:NATPE RS00920
gene id: 797303:NATPE_RS00920
uniprot id: L0JHT1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797303:NATPE RS12745
gene id: 797303:NATPE_RS12745
uniprot id: L0JNU5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

797303:NATPE RS17675
gene id: 797303:NATPE_RS17675
uniprot id: L0JSY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

797303:NATPE RS04085
gene id: 797303:NATPE_RS04085
uniprot id: L0JHG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS14400
gene id: 797303:NATPE_RS14400
uniprot id: L0JR57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS00285
gene id: 797303:NATPE_RS00285
uniprot id: L0JGM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797303:NATPE RS10375
gene id: 797303:NATPE_RS10375
uniprot id: L0JN69
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797303:NATPE RS03865
gene id: 797303:NATPE_RS03865
uniprot id: L0JK31
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

797303:NATPE RS14520
gene id: 797303:NATPE_RS14520
uniprot id: L0JMY2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

797303:NATPE RS11320
gene id: 797303:NATPE_RS11320
uniprot id: L9YMZ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17535
gene id: 797303:NATPE_RS17535
uniprot id: L0JRL6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

797303:NATPE RS01120
gene id: 797303:NATPE_RS01120
uniprot id: L9YVL4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14605
gene id: 797303:NATPE_RS14605
uniprot id: L0JPY6
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

797303:NATPE RS00350
gene id: 797303:NATPE_RS00350
uniprot id: L0JHH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

797303:NATPE RS04645
gene id: 797303:NATPE_RS04645
uniprot id: L0JKJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

797303:NATPE RS10685
gene id: 797303:NATPE_RS10685
uniprot id: L0JP11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797303:NATPE RS08895
gene id: 797303:NATPE_RS08895
uniprot id: L0JJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

797303:NATPE RS18480
gene id: 797303:NATPE_RS18480
uniprot id: L0JSM3
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797303:NATPE RS10325
gene id: 797303:NATPE_RS10325
uniprot id: L0JNU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

797303:NATPE RS01645
gene id: 797303:NATPE_RS01645
uniprot id: L9YY86
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS09510
gene id: 797303:NATPE_RS09510
uniprot id: L0JNB8
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS04420
gene id: 797303:NATPE_RS04420
uniprot id: L0JKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

797303:NATPE RS05630
gene id: 797303:NATPE_RS05630
uniprot id: L0JKG6
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

797303:NATPE RS08160
gene id: 797303:NATPE_RS08160
uniprot id: L0JL65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

797303:NATPE RS20235
gene id: 797303:NATPE_RS20235
uniprot id: L0JRZ9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

797303:NATPE RS09330
gene id: 797303:NATPE_RS09330
uniprot id: L9YGT3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04135
gene id: 797303:NATPE_RS04135
uniprot id: L0JGW2
names: Subcellular Location Annotation
messages: Cytoplasm

797303:NATPE RS02045
gene id: 797303:NATPE_RS02045
uniprot id: L0JGE3
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

797303:NATPE RS06625
gene id: 797303:NATPE_RS06625
uniprot id: L0JJ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

797303:NATPE RS05730
gene id: 797303:NATPE_RS05730
uniprot id: L0JKI5
names: Similarity
messages: Belongs to the peptidase S8 family.

797303:NATPE RS04280
gene id: 797303:NATPE_RS04280
uniprot id: L0JIZ5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

797303:NATPE RS01080
gene id: 797303:NATPE_RS01080
uniprot id: L9Y732
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14365
gene id: 797303:NATPE_RS14365
uniprot id: L0JNM3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797303:NATPE RS14465
gene id: 797303:NATPE_RS14465
uniprot id: L0JNP2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS16335
gene id: 797303:NATPE_RS16335
uniprot id: L0JS74
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

797303:NATPE RS14715
gene id: 797303:NATPE_RS14715
uniprot id: L0JQ05
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

797303:NATPE RS17300
gene id: 797303:NATPE_RS17300
uniprot id: L0JSR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

797303:NATPE RS12795
gene id: 797303:NATPE_RS12795
uniprot id: L0JNV4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

797303:NATPE RS14450
gene id: 797303:NATPE_RS14450
uniprot id: L0JR65
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05290
gene id: 797303:NATPE_RS05290
uniprot id: L0JKW9
names: Similarity
messages: Belongs to the UPF0284 family.

797303:NATPE RS16430
gene id: 797303:NATPE_RS16430
uniprot id: L0JRK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

797303:NATPE RS06835
gene id: 797303:NATPE_RS06835
uniprot id: L0JJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

797303:NATPE RS19635
gene id: 797303:NATPE_RS19635
uniprot id: L0JQV9
names: Similarity
messages: Belongs to the UPF0175 family.

797303:NATPE RS17705
gene id: 797303:NATPE_RS17705
uniprot id: L0JS81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

797303:NATPE RS03145
gene id: 797303:NATPE_RS03145
uniprot id: L0JI97
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS12120
gene id: 797303:NATPE_RS12120
uniprot id: L0JPU1
names: Similarity
messages: Belongs to the UPF0212 family.

797303:NATPE RS04275
gene id: 797303:NATPE_RS04275
uniprot id: L0JJQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS07700
gene id: 797303:NATPE_RS07700
uniprot id: L9YI91
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS00065
gene id: 797303:NATPE_RS00065
uniprot id: L0JF93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

797303:NATPE RS13625
gene id: 797303:NATPE_RS13625
uniprot id: L0JMC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS04945
gene id: 797303:NATPE_RS04945
uniprot id: L0JKP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

797303:NATPE RS04200
gene id: 797303:NATPE_RS04200
uniprot id: L9Z4K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS09585
gene id: 797303:NATPE_RS09585
uniprot id: L0JK27
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

797303:NATPE RS04485
gene id: 797303:NATPE_RS04485
uniprot id: L0JHS0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

797303:NATPE RS02110
gene id: 797303:NATPE_RS02110
uniprot id: L0JJ59
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS15575
gene id: 797303:NATPE_RS15575
uniprot id: L0JPA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

797303:NATPE RS01360
gene id: 797303:NATPE_RS01360
uniprot id: L0JIQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

797303:NATPE RS19740
gene id: 797303:NATPE_RS19740
uniprot id: L9Y859
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS06990
gene id: 797303:NATPE_RS06990
uniprot id: L0JIL7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05460
gene id: 797303:NATPE_RS05460
uniprot id: L0JJM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS05635
gene id: 797303:NATPE_RS05635
uniprot id: L9Z5Z6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS18125
gene id: 797303:NATPE_RS18125
uniprot id: L0JSF7
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

797303:NATPE RS13135
gene id: 797303:NATPE_RS13135
uniprot id: L0JPP3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

797303:NATPE RS12260
gene id: 797303:NATPE_RS12260
uniprot id: L0JPW7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

797303:NATPE RS18725
gene id: 797303:NATPE_RS18725
uniprot id: L9YQQ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS15570
gene id: 797303:NATPE_RS15570
uniprot id: L0JQH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

797303:NATPE RS03325
gene id: 797303:NATPE_RS03325
uniprot id: L0JH15
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797303:NATPE RS05555
gene id: 797303:NATPE_RS05555
uniprot id: L0JJP3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS13905
gene id: 797303:NATPE_RS13905
uniprot id: L0JMI5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS09160
gene id: 797303:NATPE_RS09160
uniprot id: L0JMK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS02545
gene id: 797303:NATPE_RS02545
uniprot id: L0JIR2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS10465
gene id: 797303:NATPE_RS10465
uniprot id: L0JKI4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

797303:NATPE RS00660
gene id: 797303:NATPE_RS00660
uniprot id: L0JIB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

797303:NATPE RS05045
gene id: 797303:NATPE_RS05045
uniprot id: L0JK46
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS18100
gene id: 797303:NATPE_RS18100
uniprot id: L0JSF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

797303:NATPE RS05570
gene id: 797303:NATPE_RS05570
uniprot id: L0JHP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS02650
gene id: 797303:NATPE_RS02650
uniprot id: L0JI02
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

797303:NATPE RS13405
gene id: 797303:NATPE_RS13405
uniprot id: L0JN03
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

797303:NATPE RS07885
gene id: 797303:NATPE_RS07885
uniprot id: L0JJ22
names: Caution
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS10995
gene id: 797303:NATPE_RS10995
uniprot id: L0JMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

797303:NATPE RS10710
gene id: 797303:NATPE_RS10710
uniprot id: L0JP17
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

797303:NATPE RS11965
gene id: 797303:NATPE_RS11965
uniprot id: L9YJG5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS20735
gene id: 797303:NATPE_RS20735
uniprot id: L9YDN0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS05790
gene id: 797303:NATPE_RS05790
uniprot id: L9Z3Z8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS00495
gene id: 797303:NATPE_RS00495
uniprot id: L0JFG4
names: Similarity
messages: Belongs to the peptidase S8 family.

797303:NATPE RS10860
gene id: 797303:NATPE_RS10860
uniprot id: L0JP39
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

797303:NATPE RS08810
gene id: 797303:NATPE_RS08810
uniprot id: L0JLK3
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS07370
gene id: 797303:NATPE_RS07370
uniprot id: L0JIT3
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS09210
gene id: 797303:NATPE_RS09210
uniprot id: L9YF91
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS10680
gene id: 797303:NATPE_RS10680
uniprot id: L0JKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797303:NATPE RS07100
gene id: 797303:NATPE_RS07100
uniprot id: L9Z7Z7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS09400
gene id: 797303:NATPE_RS09400
uniprot id: L0JMP5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

797303:NATPE RS04270
gene id: 797303:NATPE_RS04270
uniprot id: L0JKC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

797303:NATPE RS15370
gene id: 797303:NATPE_RS15370
uniprot id: L9YCW1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS12370
gene id: 797303:NATPE_RS12370
uniprot id: L0JPB0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS16490
gene id: 797303:NATPE_RS16490
uniprot id: L0JR18
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

797303:NATPE RS03860
gene id: 797303:NATPE_RS03860
uniprot id: L0JGQ3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

797303:NATPE RS17910
gene id: 797303:NATPE_RS17910
uniprot id: L9YCK6
names: Caution
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS08035
gene id: 797303:NATPE_RS08035
uniprot id: L0JJV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

797303:NATPE RS14990
gene id: 797303:NATPE_RS14990
uniprot id: L0JN63
names: Similarity
messages: Belongs to the AOR/FOR family.

797303:NATPE RS05285
gene id: 797303:NATPE_RS05285
uniprot id: L0JHI8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS06145
gene id: 797303:NATPE_RS06145
uniprot id: L0JKS3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

797303:NATPE RS05870
gene id: 797303:NATPE_RS05870
uniprot id: L0JHW2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

797303:NATPE RS05545
gene id: 797303:NATPE_RS05545
uniprot id: L0JL27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

797303:NATPE RS13630
gene id: 797303:NATPE_RS13630
uniprot id: L0JQN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

797303:NATPE RS07600
gene id: 797303:NATPE_RS07600
uniprot id: L0JKW1
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

797303:NATPE RS11860
gene id: 797303:NATPE_RS11860
uniprot id: L0JNE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

797303:NATPE RS10475
gene id: 797303:NATPE_RS10475
uniprot id: L0JN86
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

797303:NATPE RS04415
gene id: 797303:NATPE_RS04415
uniprot id: L0JH37
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS04580
gene id: 797303:NATPE_RS04580
uniprot id: L9Z4C3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS03650
gene id: 797303:NATPE_RS03650
uniprot id: L0JIJ2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS13035
gene id: 797303:NATPE_RS13035
uniprot id: L0JPM2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

797303:NATPE RS04310
gene id: 797303:NATPE_RS04310
uniprot id: L0JHN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

797303:NATPE RS09380
gene id: 797303:NATPE_RS09380
uniprot id: L9YUN1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS01375
gene id: 797303:NATPE_RS01375
uniprot id: L0JFY5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

797303:NATPE RS14805
gene id: 797303:NATPE_RS14805
uniprot id: L9YM57
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS01890
gene id: 797303:NATPE_RS01890
uniprot id: L0JJ19
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

797303:NATPE RS00540
gene id: 797303:NATPE_RS00540
uniprot id: L0JHJ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS03285
gene id: 797303:NATPE_RS03285
uniprot id: L0JGD1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

797303:NATPE RS14385
gene id: 797303:NATPE_RS14385
uniprot id: L0JPT5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS13845
gene id: 797303:NATPE_RS13845
uniprot id: L0JPF6
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS15235
gene id: 797303:NATPE_RS15235
uniprot id: L0JP36
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

797303:NATPE RS13545
gene id: 797303:NATPE_RS13545
uniprot id: L0JP97
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS14840
gene id: 797303:NATPE_RS14840
uniprot id: L0JN39
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

797303:NATPE RS00770
gene id: 797303:NATPE_RS00770
uniprot id: L0JGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

797303:NATPE RS15045
gene id: 797303:NATPE_RS15045
uniprot id: L0JRG7
names: Similarity
messages: Belongs to the TPP enzyme family.

797303:NATPE RS17445
gene id: 797303:NATPE_RS17445
uniprot id: L0JPJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

797303:NATPE RS06095
gene id: 797303:NATPE_RS06095
uniprot id: L9Z505
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17175
gene id: 797303:NATPE_RS17175
uniprot id: L0JRF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

797303:NATPE RS13065
gene id: 797303:NATPE_RS13065
uniprot id: L0JNZ9
names: Similarity
messages: Belongs to the DtxR/MntR family.

797303:NATPE RS14010
gene id: 797303:NATPE_RS14010
uniprot id: L0JQW7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

797303:NATPE RS14710
gene id: 797303:NATPE_RS14710
uniprot id: L0JQL2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS12390
gene id: 797303:NATPE_RS12390
uniprot id: L9YK08
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS05490
gene id: 797303:NATPE_RS05490
uniprot id: L0JIB1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

797303:NATPE RS11655
gene id: 797303:NATPE_RS11655
uniprot id: L0JNX6
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

797303:NATPE RS16500
gene id: 797303:NATPE_RS16500
uniprot id: L0JP05
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

797303:NATPE RS04255
gene id: 797303:NATPE_RS04255
uniprot id: L0JIY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

797303:NATPE RS01725
gene id: 797303:NATPE_RS01725
uniprot id: L0JG77
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

797303:NATPE RS00840
gene id: 797303:NATPE_RS00840
uniprot id: L0JHR4
names: Similarity
messages: Belongs to the selenium-binding protein family.

797303:NATPE RS04350
gene id: 797303:NATPE_RS04350
uniprot id: L0JJR5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

797303:NATPE RS06840
gene id: 797303:NATPE_RS06840
uniprot id: L0JIJ3
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

797303:NATPE RS02155
gene id: 797303:NATPE_RS02155
uniprot id: L0JFT3
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS16760
gene id: 797303:NATPE_RS16760
uniprot id: L0JR94
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS09950
gene id: 797303:NATPE_RS09950
uniprot id: L0JM91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

797303:NATPE RS15640
gene id: 797303:NATPE_RS15640
uniprot id: L0JQJ3
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797303:NATPE RS17800
gene id: 797303:NATPE_RS17800
uniprot id: L0JRR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS18555
gene id: 797303:NATPE_RS18555
uniprot id: L0JSP0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

797303:NATPE RS12775
gene id: 797303:NATPE_RS12775
uniprot id: L0JMM2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS11830
gene id: 797303:NATPE_RS11830
uniprot id: L0JP12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797303:NATPE RS06535
gene id: 797303:NATPE_RS06535
uniprot id: L0JLN1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS13870
gene id: 797303:NATPE_RS13870
uniprot id: L0JPG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

797303:NATPE RS16840
gene id: 797303:NATPE_RS16840
uniprot id: L9YCU7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04215
gene id: 797303:NATPE_RS04215
uniprot id: L0JKB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

797303:NATPE RS18110
gene id: 797303:NATPE_RS18110
uniprot id: L0JQQ8
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS17075
gene id: 797303:NATPE_RS17075
uniprot id: L0JRD9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

797303:NATPE RS16715
gene id: 797303:NATPE_RS16715
uniprot id: L0JP70
names: Similarity
messages: Belongs to the Ahb/Nir family.

797303:NATPE RS03795
gene id: 797303:NATPE_RS03795
uniprot id: L0JJD3
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

797303:NATPE RS17480
gene id: 797303:NATPE_RS17480
uniprot id: L0JS44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

797303:NATPE RS06110
gene id: 797303:NATPE_RS06110
uniprot id: L0JIM8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

797303:NATPE RS14510
gene id: 797303:NATPE_RS14510
uniprot id: L9YRV1
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11550
gene id: 797303:NATPE_RS11550
uniprot id: L0JPI4
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

797303:NATPE RS13265
gene id: 797303:NATPE_RS13265
uniprot id: L9YHY7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS10010
gene id: 797303:NATPE_RS10010
uniprot id: L0JKA6
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

797303:NATPE RS07560
gene id: 797303:NATPE_RS07560
uniprot id: L0JIW6
names: Similarity
messages: Belongs to the peptidase S8 family.

797303:NATPE RS08525
gene id: 797303:NATPE_RS08525
uniprot id: L0JMR0
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05920
gene id: 797303:NATPE_RS05920
uniprot id: L0JHX2
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS10450
gene id: 797303:NATPE_RS10450
uniprot id: L0JN80
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

797303:NATPE RS07530
gene id: 797303:NATPE_RS07530
uniprot id: L0JKU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

797303:NATPE RS06490
gene id: 797303:NATPE_RS06490
uniprot id: L0JK86
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS02915
gene id: 797303:NATPE_RS02915
uniprot id: L0JG55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

797303:NATPE RS15385
gene id: 797303:NATPE_RS15385
uniprot id: L9YDY5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04220
gene id: 797303:NATPE_RS04220
uniprot id: L0JJN5
names: Similarity
messages: Belongs to the UPF0045 family.

797303:NATPE RS00365
gene id: 797303:NATPE_RS00365
uniprot id: L0JEQ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS18260
gene id: 797303:NATPE_RS18260
uniprot id: L9Y9U2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS15655
gene id: 797303:NATPE_RS15655
uniprot id: L0JRT8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797303:NATPE RS02225
gene id: 797303:NATPE_RS02225
uniprot id: L0JFU4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797303:NATPE RS17105
gene id: 797303:NATPE_RS17105
uniprot id: L0JQ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

797303:NATPE RS19495
gene id: 797303:NATPE_RS19495
uniprot id: L0JST7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS17065
gene id: 797303:NATPE_RS17065
uniprot id: L0JSM9
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS14855
gene id: 797303:NATPE_RS14855
uniprot id: L0JNW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

797303:NATPE RS00305
gene id: 797303:NATPE_RS00305
uniprot id: L0JHG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

797303:NATPE RS09625
gene id: 797303:NATPE_RS09625
uniprot id: L0JM25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

797303:NATPE RS20150
gene id: 797303:NATPE_RS20150
uniprot id: L0JT57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

797303:NATPE RS01270
gene id: 797303:NATPE_RS01270
uniprot id: L0JI04
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

797303:NATPE RS09565
gene id: 797303:NATPE_RS09565
uniprot id: L0JNC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

797303:NATPE RS13860
gene id: 797303:NATPE_RS13860
uniprot id: L0JQT1
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05495
gene id: 797303:NATPE_RS05495
uniprot id: L9Z7F2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS03830
gene id: 797303:NATPE_RS03830
uniprot id: L0JHB4
names: Subunit
messages: Homotetramer.

797303:NATPE RS09835
gene id: 797303:NATPE_RS09835
uniprot id: L0JKY7
names: Similarity
messages: Belongs to the UPF0145 family.

797303:NATPE RS06775
gene id: 797303:NATPE_RS06775
uniprot id: L0JLT8
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS17245
gene id: 797303:NATPE_RS17245
uniprot id: L0JPG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

797303:NATPE RS01535
gene id: 797303:NATPE_RS01535
uniprot id: L9YXA6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11735
gene id: 797303:NATPE_RS11735
uniprot id: L0JPM1
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

797303:NATPE RS05950
gene id: 797303:NATPE_RS05950
uniprot id: L0JL99
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

797303:NATPE RS12490
gene id: 797303:NATPE_RS12490
uniprot id: L0JPZ8
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS15785
gene id: 797303:NATPE_RS15785
uniprot id: L0JQM3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS05005
gene id: 797303:NATPE_RS05005
uniprot id: L0JJD4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

797303:NATPE RS20785
gene id: 797303:NATPE_RS20785
uniprot id: L0JSA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS05180
gene id: 797303:NATPE_RS05180
uniprot id: L0JI49
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS03660
gene id: 797303:NATPE_RS03660
uniprot id: L0JGL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

797303:NATPE RS01820
gene id: 797303:NATPE_RS01820
uniprot id: L0JG99
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS20030
gene id: 797303:NATPE_RS20030
uniprot id: L9Y8B2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS20695
gene id: 797303:NATPE_RS20695
uniprot id: L0JRF7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS03580
gene id: 797303:NATPE_RS03580
uniprot id: L0JIH6
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

797303:NATPE RS04315
gene id: 797303:NATPE_RS04315
uniprot id: L0JH18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS10950
gene id: 797303:NATPE_RS10950
uniprot id: L0JMS6
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

797303:NATPE RS11180
gene id: 797303:NATPE_RS11180
uniprot id: L0JLN6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797303:NATPE RS17010
gene id: 797303:NATPE_RS17010
uniprot id: L0JPC0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

797303:NATPE RS17190
gene id: 797303:NATPE_RS17190
uniprot id: L0JSP9
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

797303:NATPE RS13470
gene id: 797303:NATPE_RS13470
uniprot id: L0JP74
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS18690
gene id: 797303:NATPE_RS18690
uniprot id: L9YUH3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS00500
gene id: 797303:NATPE_RS00500
uniprot id: L0JES7
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

797303:NATPE RS01720
gene id: 797303:NATPE_RS01720
uniprot id: L0JHI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

797303:NATPE RS07715
gene id: 797303:NATPE_RS07715
uniprot id: L0JKY5
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

797303:NATPE RS07915
gene id: 797303:NATPE_RS07915
uniprot id: L0JMF0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797303:NATPE RS04680
gene id: 797303:NATPE_RS04680
uniprot id: L0JHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

797303:NATPE RS18065
gene id: 797303:NATPE_RS18065
uniprot id: L0JSE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS12170
gene id: 797303:NATPE_RS12170
uniprot id: L0JP76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

797303:NATPE RS12250
gene id: 797303:NATPE_RS12250
uniprot id: L0JMC5
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

797303:NATPE RS01440
gene id: 797303:NATPE_RS01440
uniprot id: L0JH99
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797303:NATPE RS15125
gene id: 797303:NATPE_RS15125
uniprot id: L0JQU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797303:NATPE RS02670
gene id: 797303:NATPE_RS02670
uniprot id: L0JIT2
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

797303:NATPE RS09180
gene id: 797303:NATPE_RS09180
uniprot id: L9YE67
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS02160
gene id: 797303:NATPE_RS02160
uniprot id: L0JJ70
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

797303:NATPE RS05025
gene id: 797303:NATPE_RS05025
uniprot id: L0JK41
names: Similarity
messages: Belongs to the UPF0215 family.

797303:NATPE RS02975
gene id: 797303:NATPE_RS02975
uniprot id: L0JIX9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS04130
gene id: 797303:NATPE_RS04130
uniprot id: L0JHH5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

797303:NATPE RS00445
gene id: 797303:NATPE_RS00445
uniprot id: L0JI79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

797303:NATPE RS16550
gene id: 797303:NATPE_RS16550
uniprot id: L0JRM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

797303:NATPE RS07960
gene id: 797303:NATPE_RS07960
uniprot id: L0JJ36
names: Subcellular Location Annotation
messages: Nucleus

797303:NATPE RS16480
gene id: 797303:NATPE_RS16480
uniprot id: L0JSA6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

797303:NATPE RS03850
gene id: 797303:NATPE_RS03850
uniprot id: L0JIN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylamine corrinoid protein family.
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

797303:NATPE RS18250
gene id: 797303:NATPE_RS18250
uniprot id: L0JS05
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS15260
gene id: 797303:NATPE_RS15260
uniprot id: L0JNB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

797303:NATPE RS17305
gene id: 797303:NATPE_RS17305
uniprot id: L0JS15
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS17220
gene id: 797303:NATPE_RS17220
uniprot id: L0JPF2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

797303:NATPE RS10510
gene id: 797303:NATPE_RS10510
uniprot id: L0JLA6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

797303:NATPE RS12660
gene id: 797303:NATPE_RS12660
uniprot id: L0JQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

797303:NATPE RS08010
gene id: 797303:NATPE_RS08010
uniprot id: L0JJ47
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS11845
gene id: 797303:NATPE_RS11845
uniprot id: L0JLE6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

797303:NATPE RS17465
gene id: 797303:NATPE_RS17465
uniprot id: L0JQE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS10430
gene id: 797303:NATPE_RS10430
uniprot id: L0JL92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

797303:NATPE RS06565
gene id: 797303:NATPE_RS06565
uniprot id: L9Z5M1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS08180
gene id: 797303:NATPE_RS08180
uniprot id: L0JL70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

797303:NATPE RS18305
gene id: 797303:NATPE_RS18305
uniprot id: L0JQU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS09660
gene id: 797303:NATPE_RS09660
uniprot id: L0JNF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

797303:NATPE RS09465
gene id: 797303:NATPE_RS09465
uniprot id: L0JMQ7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05865
gene id: 797303:NATPE_RS05865
uniprot id: L0JIH3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797303:NATPE RS11145
gene id: 797303:NATPE_RS11145
uniprot id: L9YMU6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS20775
gene id: 797303:NATPE_RS20775
uniprot id: L0JUQ5
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

797303:NATPE RS03230
gene id: 797303:NATPE_RS03230
uniprot id: L0JGC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS00250
gene id: 797303:NATPE_RS00250
uniprot id: L0JHF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

797303:NATPE RS17670
gene id: 797303:NATPE_RS17670
uniprot id: L0JPN7
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

797303:NATPE RS07340
gene id: 797303:NATPE_RS07340
uniprot id: L9ZA52
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17715
gene id: 797303:NATPE_RS17715
uniprot id: L0JQI4
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

797303:NATPE RS09870
gene id: 797303:NATPE_RS09870
uniprot id: L0JNJ6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

797303:NATPE RS01035
gene id: 797303:NATPE_RS01035
uniprot id: L0JF40
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797303:NATPE RS07235
gene id: 797303:NATPE_RS07235
uniprot id: L0JIR1
names: Subcellular Location Annotation
messages: Cytoplasm

797303:NATPE RS00735
gene id: 797303:NATPE_RS00735
uniprot id: L0JIC6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS06420
gene id: 797303:NATPE_RS06420
uniprot id: L0JIV0
names: Similarity
messages: Belongs to the PrpD family.

797303:NATPE RS18235
gene id: 797303:NATPE_RS18235
uniprot id: L0JPZ7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS07650
gene id: 797303:NATPE_RS07650
uniprot id: L0JKX1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

797303:NATPE RS09220
gene id: 797303:NATPE_RS09220
uniprot id: L9YHA9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS06470
gene id: 797303:NATPE_RS06470
uniprot id: L0JIW2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS09520
gene id: 797303:NATPE_RS09520
uniprot id: L0JM07
names: Similarity
messages: Belongs to the PEPCase type 1 family.

797303:NATPE RS18575
gene id: 797303:NATPE_RS18575
uniprot id: L0JQ69
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS03475
gene id: 797303:NATPE_RS03475
uniprot id: L9YN31
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11310
gene id: 797303:NATPE_RS11310
uniprot id: L0JNP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

797303:NATPE RS08115
gene id: 797303:NATPE_RS08115
uniprot id: L0JJX7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS15310
gene id: 797303:NATPE_RS15310
uniprot id: L0JNB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS06610
gene id: 797303:NATPE_RS06610
uniprot id: L0JLP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

797303:NATPE RS08515
gene id: 797303:NATPE_RS08515
uniprot id: L0JK64
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS17030
gene id: 797303:NATPE_RS17030
uniprot id: L0JQ74
names: Similarity
messages: Belongs to the AOR/FOR family.

797303:NATPE RS11420
gene id: 797303:NATPE_RS11420
uniprot id: L0JNS0
names: Similarity
messages: Belongs to the Dps family.

797303:NATPE RS11635
gene id: 797303:NATPE_RS11635
uniprot id: L0JN90
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

797303:NATPE RS01305
gene id: 797303:NATPE_RS01305
uniprot id: L0JFW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

797303:NATPE RS00855
gene id: 797303:NATPE_RS00855
uniprot id: L0JF02
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

797303:NATPE RS05970
gene id: 797303:NATPE_RS05970
uniprot id: L0JLA3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

797303:NATPE RS01825
gene id: 797303:NATPE_RS01825
uniprot id: L0JFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

797303:NATPE RS20230
gene id: 797303:NATPE_RS20230
uniprot id: L0JT78
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

797303:NATPE RS09155
gene id: 797303:NATPE_RS09155
uniprot id: L0JN60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS06065
gene id: 797303:NATPE_RS06065
uniprot id: L0JIL8
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS17185
gene id: 797303:NATPE_RS17185
uniprot id: L0JPE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797303:NATPE RS18785
gene id: 797303:NATPE_RS18785
uniprot id: L0JSB8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

797303:NATPE RS02835
gene id: 797303:NATPE_RS02835
uniprot id: L0JG44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

797303:NATPE RS00725
gene id: 797303:NATPE_RS00725
uniprot id: L9Y7U6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS03590
gene id: 797303:NATPE_RS03590
uniprot id: L0JGJ8
names: Similarity
messages: Belongs to the RutC family.

797303:NATPE RS15635
gene id: 797303:NATPE_RS15635
uniprot id: L0JR34
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS07090
gene id: 797303:NATPE_RS07090
uniprot id: L0JIN6
names: Similarity
messages: Belongs to the glutaredoxin family.

797303:NATPE RS07855
gene id: 797303:NATPE_RS07855
uniprot id: L0JJS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

797303:NATPE RS04690
gene id: 797303:NATPE_RS04690
uniprot id: L0JKJ7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS02150
gene id: 797303:NATPE_RS02150
uniprot id: L9YZ57
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17125
gene id: 797303:NATPE_RS17125
uniprot id: L0JQ90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS08415
gene id: 797303:NATPE_RS08415
uniprot id: L0JJD2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS10740
gene id: 797303:NATPE_RS10740
uniprot id: L0JNE0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS11975
gene id: 797303:NATPE_RS11975
uniprot id: L9YLC8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14175
gene id: 797303:NATPE_RS14175
uniprot id: L0JMR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS00790
gene id: 797303:NATPE_RS00790
uniprot id: L0JHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

797303:NATPE RS02735
gene id: 797303:NATPE_RS02735
uniprot id: L0JG29
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

797303:NATPE RS15565
gene id: 797303:NATPE_RS15565
uniprot id: L0JR21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

797303:NATPE RS10645
gene id: 797303:NATPE_RS10645
uniprot id: L9YT93
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14345
gene id: 797303:NATPE_RS14345
uniprot id: L0JMV0
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS14425
gene id: 797303:NATPE_RS14425
uniprot id: L0JR61
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

797303:NATPE RS09540
gene id: 797303:NATPE_RS09540
uniprot id: L9YWB9
names: Caution
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS01735
gene id: 797303:NATPE_RS01735
uniprot id: L0JIZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

797303:NATPE RS17835
gene id: 797303:NATPE_RS17835
uniprot id: L0JPS5
names: Similarity
messages: Belongs to the group II decarboxylase family.

797303:NATPE RS07500
gene id: 797303:NATPE_RS07500
uniprot id: L0JLK5
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS09215
gene id: 797303:NATPE_RS09215
uniprot id: L0JMM0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS03825
gene id: 797303:NATPE_RS03825
uniprot id: L0JIM9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS16515
gene id: 797303:NATPE_RS16515
uniprot id: L0JRM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

797303:NATPE RS02365
gene id: 797303:NATPE_RS02365
uniprot id: L0JJA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

797303:NATPE RS20685
gene id: 797303:NATPE_RS20685
uniprot id: L9YDM3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS00730
gene id: 797303:NATPE_RS00730
uniprot id: L9Y7R7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS02060
gene id: 797303:NATPE_RS02060
uniprot id: L0JII2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

797303:NATPE RS18195
gene id: 797303:NATPE_RS18195
uniprot id: L0JT82
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797303:NATPE RS06950
gene id: 797303:NATPE_RS06950
uniprot id: L0JLA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS10245
gene id: 797303:NATPE_RS10245
uniprot id: L0JL57
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

797303:NATPE RS05440
gene id: 797303:NATPE_RS05440
uniprot id: L0JJM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

797303:NATPE RS08820
gene id: 797303:NATPE_RS08820
uniprot id: L9YJ31
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS12135
gene id: 797303:NATPE_RS12135
uniprot id: L0JLJ3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

797303:NATPE RS11750
gene id: 797303:NATPE_RS11750
uniprot id: L0JM34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS07240
gene id: 797303:NATPE_RS07240
uniprot id: L0JM17
names: Similarity
messages: Belongs to the arginase family.

797303:NATPE RS16520
gene id: 797303:NATPE_RS16520
uniprot id: L0JR26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

797303:NATPE RS03235
gene id: 797303:NATPE_RS03235
uniprot id: L0JJQ8
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS08055
gene id: 797303:NATPE_RS08055
uniprot id: L0JLV5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

797303:NATPE RS05955
gene id: 797303:NATPE_RS05955
uniprot id: L0JKM8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

797303:NATPE RS18140
gene id: 797303:NATPE_RS18140
uniprot id: L0JPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797303:NATPE RS15470
gene id: 797303:NATPE_RS15470
uniprot id: L0JQF6
names: Similarity
messages: Belongs to the peptidase S49 family.

797303:NATPE RS12740
gene id: 797303:NATPE_RS12740
uniprot id: L0JPH2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

797303:NATPE RS14760
gene id: 797303:NATPE_RS14760
uniprot id: L0JQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

797303:NATPE RS01070
gene id: 797303:NATPE_RS01070
uniprot id: L0JHW3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

797303:NATPE RS16150
gene id: 797303:NATPE_RS16150
uniprot id: L0JNT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Homodimer.

797303:NATPE RS09970
gene id: 797303:NATPE_RS09970
uniprot id: L0JN00
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

797303:NATPE RS11690
gene id: 797303:NATPE_RS11690
uniprot id: L0JM24
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS05565
gene id: 797303:NATPE_RS05565
uniprot id: L9Z5B6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS12895
gene id: 797303:NATPE_RS12895
uniprot id: L0JPJ8
names: Similarity
messages: Belongs to the NAD synthetase family.

797303:NATPE RS06630
gene id: 797303:NATPE_RS06630
uniprot id: L0JIE1
names: Function
messages: Part of a potassium transport system.

797303:NATPE RS09915
gene id: 797303:NATPE_RS09915
uniprot id: L9YY89
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS15290
gene id: 797303:NATPE_RS15290
uniprot id: L0JRL7
names: Similarity
messages: Belongs to the peptidase S33 family.

797303:NATPE RS07540
gene id: 797303:NATPE_RS07540
uniprot id: L0JIW3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797303:NATPE RS04325
gene id: 797303:NATPE_RS04325
uniprot id: L0JJR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

797303:NATPE RS19790
gene id: 797303:NATPE_RS19790
uniprot id: L0JU52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

797303:NATPE RS02330
gene id: 797303:NATPE_RS02330
uniprot id: L0JGI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

797303:NATPE RS14095
gene id: 797303:NATPE_RS14095
uniprot id: L0JNG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS04335
gene id: 797303:NATPE_RS04335
uniprot id: L0JHP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

797303:NATPE RS00415
gene id: 797303:NATPE_RS00415
uniprot id: L0JER3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797303:NATPE RS20065
gene id: 797303:NATPE_RS20065
uniprot id: L0JR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS01555
gene id: 797303:NATPE_RS01555
uniprot id: L0JHC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

797303:NATPE RS05105
gene id: 797303:NATPE_RS05105
uniprot id: L0JI36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS17765
gene id: 797303:NATPE_RS17765
uniprot id: L0JT01
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS00590
gene id: 797303:NATPE_RS00590
uniprot id: L0JHK9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS17530
gene id: 797303:NATPE_RS17530
uniprot id: L0JS52
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS18095
gene id: 797303:NATPE_RS18095
uniprot id: L9YA36
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS20575
gene id: 797303:NATPE_RS20575
uniprot id: L0JRD1
names: Similarity
messages: Belongs to the UPF0175 family.

797303:NATPE RS17410
gene id: 797303:NATPE_RS17410
uniprot id: L0JQD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797303:NATPE RS17605
gene id: 797303:NATPE_RS17605
uniprot id: L0JS65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

797303:NATPE RS04320
gene id: 797303:NATPE_RS04320
uniprot id: L0JKD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS16255
gene id: 797303:NATPE_RS16255
uniprot id: L0JPP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

797303:NATPE RS07430
gene id: 797303:NATPE_RS07430
uniprot id: L0JLJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

797303:NATPE RS17575
gene id: 797303:NATPE_RS17575
uniprot id: L0JS60
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS14225
gene id: 797303:NATPE_RS14225
uniprot id: L0JMS5
names: Function
messages: Part of a potassium transport system.

797303:NATPE RS06220
gene id: 797303:NATPE_RS06220
uniprot id: L0JK28
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS03630
gene id: 797303:NATPE_RS03630
uniprot id: L0JH76
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS09795
gene id: 797303:NATPE_RS09795
uniprot id: L0JNI1
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS18255
gene id: 797303:NATPE_RS18255
uniprot id: L0JQT7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS00085
gene id: 797303:NATPE_RS00085
uniprot id: L0JGI7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

797303:NATPE RS19270
gene id: 797303:NATPE_RS19270
uniprot id: L0JQP8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

797303:NATPE RS08580
gene id: 797303:NATPE_RS08580
uniprot id: L0JK81
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

797303:NATPE RS06525
gene id: 797303:NATPE_RS06525
uniprot id: L0JIX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS02620
gene id: 797303:NATPE_RS02620
uniprot id: L0JIS4
names: Similarity
messages: Belongs to the AAA ATPase family.

797303:NATPE RS15095
gene id: 797303:NATPE_RS15095
uniprot id: L0JRH7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

797303:NATPE RS13740
gene id: 797303:NATPE_RS13740
uniprot id: L0JPD4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

797303:NATPE RS16690
gene id: 797303:NATPE_RS16690
uniprot id: L0JQ16
names: Similarity
messages: Belongs to the asparaginase 1 family.

797303:NATPE RS17295
gene id: 797303:NATPE_RS17295
uniprot id: L0JPH3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

797303:NATPE RS15065
gene id: 797303:NATPE_RS15065
uniprot id: L0JP09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

797303:NATPE RS12340
gene id: 797303:NATPE_RS12340
uniprot id: L0JPX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

797303:NATPE RS15225
gene id: 797303:NATPE_RS15225
uniprot id: L0JQW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

797303:NATPE RS03730
gene id: 797303:NATPE_RS03730
uniprot id: L0JJC4
names: Similarity
messages: Belongs to the RutC family.

797303:NATPE RS18300
gene id: 797303:NATPE_RS18300
uniprot id: L9Y8U5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17930
gene id: 797303:NATPE_RS17930
uniprot id: L0JQL9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797303:NATPE RS17970
gene id: 797303:NATPE_RS17970
uniprot id: L0JSD1
names: Similarity
messages: Belongs to the HMBS family.

797303:NATPE RS08140
gene id: 797303:NATPE_RS08140
uniprot id: L0JJY2
names: Function
messages: Part of a potassium transport system.

797303:NATPE RS08145
gene id: 797303:NATPE_RS08145
uniprot id: L0JJ73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

797303:NATPE RS12800
gene id: 797303:NATPE_RS12800
uniprot id: L0JMM8
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS04685
gene id: 797303:NATPE_RS04685
uniprot id: L0JH85
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

797303:NATPE RS07470
gene id: 797303:NATPE_RS07470
uniprot id: L0JM62
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A 'suicide' enzyme that participates in biotin synthesis. Catalyzes the formation of (S)-8-amino-7-oxononanoate (DAN-carbamic acid) from (7R,8S)-8-amino-7-(carboxyamino)nonanoate (DAN), a function equivalent to the cannonical BioA reaction and the first half-reaction of BioD. The cellular requirement for biotin is thought be low enough that this single turnover enzyme supplies a sufficient amount of the cofactor. Overall it catalyzes three reactions: formation of a covalent linkage with 8-amino-7-oxononanoate to yield a BioU-DAN conjugate at the epsilon-amino group of Lys124 of BioU using NAD(P)H, carboxylation of the conjugate to form BioU-DAN-carbamic acid, and release of DAN-carbamic acid using NAD(P)+.
messages: Belongs to the BioU family.
messages: In cannonical biotin synthesis a pimeloyl-conjugate is transformed into biotin by the subsequent action of BioF, BioA, BioD and BioB. This enzyme replaces BioA and performs the first half-reaction of BioD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

797303:NATPE RS17180
gene id: 797303:NATPE_RS17180
uniprot id: L0JQ96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797303:NATPE RS05710
gene id: 797303:NATPE_RS05710
uniprot id: L9Z5Y1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS09350
gene id: 797303:NATPE_RS09350
uniprot id: L0JMN8
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05580
gene id: 797303:NATPE_RS05580
uniprot id: L0JKF6
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05550
gene id: 797303:NATPE_RS05550
uniprot id: L0JKF0
names: Similarity
messages: Belongs to the TrpF family.

797303:NATPE RS17745
gene id: 797303:NATPE_RS17745
uniprot id: L0JS91
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

797303:NATPE RS04440
gene id: 797303:NATPE_RS04440
uniprot id: L9Z345
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS01670
gene id: 797303:NATPE_RS01670
uniprot id: L0JHG3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797303:NATPE RS17710
gene id: 797303:NATPE_RS17710
uniprot id: L0JRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

797303:NATPE RS15265
gene id: 797303:NATPE_RS15265
uniprot id: L9YLN9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14455
gene id: 797303:NATPE_RS14455
uniprot id: L0JQH7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS04160
gene id: 797303:NATPE_RS04160
uniprot id: L0JGW8
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

797303:NATPE RS03560
gene id: 797303:NATPE_RS03560
uniprot id: L0JH59
names: Similarity
messages: Belongs to the citrate synthase family.

797303:NATPE RS01260
gene id: 797303:NATPE_RS01260
uniprot id: L0JF85
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

797303:NATPE RS07195
gene id: 797303:NATPE_RS07195
uniprot id: L9Z7Y1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS10485
gene id: 797303:NATPE_RS10485
uniprot id: L0JLA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS20670
gene id: 797303:NATPE_RS20670
uniprot id: L0JRF3
names: Function
messages: Part of a potassium transport system.

797303:NATPE RS17355
gene id: 797303:NATPE_RS17355
uniprot id: L0JS23
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797303:NATPE RS04960
gene id: 797303:NATPE_RS04960
uniprot id: L0JI09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

797303:NATPE RS13450
gene id: 797303:NATPE_RS13450
uniprot id: L0JN12
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS16585
gene id: 797303:NATPE_RS16585
uniprot id: L9YC63
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS02575
gene id: 797303:NATPE_RS02575
uniprot id: L0JHY8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

797303:NATPE RS08110
gene id: 797303:NATPE_RS08110
uniprot id: L0JL55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Homodimer.

797303:NATPE RS10750
gene id: 797303:NATPE_RS10750
uniprot id: L0JLF1
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

797303:NATPE RS02340
gene id: 797303:NATPE_RS02340
uniprot id: L0JJ99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS17170
gene id: 797303:NATPE_RS17170
uniprot id: L0JRZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

797303:NATPE RS17505
gene id: 797303:NATPE_RS17505
uniprot id: L0JS49
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

797303:NATPE RS16540
gene id: 797303:NATPE_RS16540
uniprot id: L0JP10
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

797303:NATPE RS03310
gene id: 797303:NATPE_RS03310
uniprot id: L9YL59
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS06980
gene id: 797303:NATPE_RS06980
uniprot id: L0JKJ5
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

797303:NATPE RS16190
gene id: 797303:NATPE_RS16190
uniprot id: L0JQW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

797303:NATPE RS12925
gene id: 797303:NATPE_RS12925
uniprot id: L0JMP7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS00550
gene id: 797303:NATPE_RS00550
uniprot id: L0JFH3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

797303:NATPE RS14130
gene id: 797303:NATPE_RS14130
uniprot id: L0JQB9
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS20755
gene id: 797303:NATPE_RS20755
uniprot id: L0JU09
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS08095
gene id: 797303:NATPE_RS08095
uniprot id: L0JJ62
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS13365
gene id: 797303:NATPE_RS13365
uniprot id: L0JPU9
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

797303:NATPE RS04285
gene id: 797303:NATPE_RS04285
uniprot id: L0JHN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797303:NATPE RS17935
gene id: 797303:NATPE_RS17935
uniprot id: L0JPU3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

797303:NATPE RS05330
gene id: 797303:NATPE_RS05330
uniprot id: L0JI81
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS02165
gene id: 797303:NATPE_RS02165
uniprot id: L0JIJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS18025
gene id: 797303:NATPE_RS18025
uniprot id: L0JRV7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

797303:NATPE RS02925
gene id: 797303:NATPE_RS02925
uniprot id: L9YUY0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS10550
gene id: 797303:NATPE_RS10550
uniprot id: L0JMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS02485
gene id: 797303:NATPE_RS02485
uniprot id: L0JFY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
messages: Homotetramer.

797303:NATPE RS11805
gene id: 797303:NATPE_RS11805
uniprot id: L0JPN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

797303:NATPE RS05430
gene id: 797303:NATPE_RS05430
uniprot id: L0JL01
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797303:NATPE RS15355
gene id: 797303:NATPE_RS15355
uniprot id: L0JP59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

797303:NATPE RS06125
gene id: 797303:NATPE_RS06125
uniprot id: L9Z8G7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS16525
gene id: 797303:NATPE_RS16525
uniprot id: L9YC55
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS03065
gene id: 797303:NATPE_RS03065
uniprot id: L0JJM8
names: Function
messages: Part of a potassium transport system.

797303:NATPE RS15130
gene id: 797303:NATPE_RS15130
uniprot id: L0JQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

797303:NATPE RS09990
gene id: 797303:NATPE_RS09990
uniprot id: L0JNL5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

797303:NATPE RS10815
gene id: 797303:NATPE_RS10815
uniprot id: L0JNF1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

797303:NATPE RS11765
gene id: 797303:NATPE_RS11765
uniprot id: L0JNZ6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

797303:NATPE RS14110
gene id: 797303:NATPE_RS14110
uniprot id: L0JPM8
names: Similarity
messages: Belongs to the eIF-2-alpha family.

797303:NATPE RS06970
gene id: 797303:NATPE_RS06970
uniprot id: L9Z957
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS11055
gene id: 797303:NATPE_RS11055
uniprot id: L0JLL3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS02170
gene id: 797303:NATPE_RS02170
uniprot id: L0JHR1
names: Similarity
messages: Belongs to the PDCD5 family.

797303:NATPE RS01970
gene id: 797303:NATPE_RS01970
uniprot id: L0JGC9
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS10555
gene id: 797303:NATPE_RS10555
uniprot id: L0JKK3
names: Similarity
messages: Belongs to the manganese catalase family.

797303:NATPE RS01220
gene id: 797303:NATPE_RS01220
uniprot id: L0JIM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

797303:NATPE RS10605
gene id: 797303:NATPE_RS10605
uniprot id: L0JNZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

797303:NATPE RS13090
gene id: 797303:NATPE_RS13090
uniprot id: L0JP03
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

797303:NATPE RS06050
gene id: 797303:NATPE_RS06050
uniprot id: L0JLC1
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

797303:NATPE RS15745
gene id: 797303:NATPE_RS15745
uniprot id: L0JNK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

797303:NATPE RS04365
gene id: 797303:NATPE_RS04365
uniprot id: L0JH28
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05055
gene id: 797303:NATPE_RS05055
uniprot id: L0JI29
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

797303:NATPE RS06590
gene id: 797303:NATPE_RS06590
uniprot id: L0JL22
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS18905
gene id: 797303:NATPE_RS18905
uniprot id: L0JR59
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797303:NATPE RS09785
gene id: 797303:NATPE_RS09785
uniprot id: L0JKX9
names: Similarity
messages: Belongs to the TPP enzyme family.

797303:NATPE RS06770
gene id: 797303:NATPE_RS06770
uniprot id: L0JJ50
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS00090
gene id: 797303:NATPE_RS00090
uniprot id: L0JF98
names: Similarity
messages: Belongs to the UPF0175 family.

797303:NATPE RS09955
gene id: 797303:NATPE_RS09955
uniprot id: L0JL10
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

797303:NATPE RS09775
gene id: 797303:NATPE_RS09775
uniprot id: L9YXT6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS08075
gene id: 797303:NATPE_RS08075
uniprot id: L0JMH8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

797303:NATPE RS20495
gene id: 797303:NATPE_RS20495
uniprot id: L0JUJ5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

797303:NATPE RS16390
gene id: 797303:NATPE_RS16390
uniprot id: L0JQZ8
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

797303:NATPE RS02920
gene id: 797303:NATPE_RS02920
uniprot id: L0JJK4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797303:NATPE RS16755
gene id: 797303:NATPE_RS16755
uniprot id: L9YDH1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14765
gene id: 797303:NATPE_RS14765
uniprot id: L0JNU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

797303:NATPE RS02180
gene id: 797303:NATPE_RS02180
uniprot id: L0JFT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

797303:NATPE RS13565
gene id: 797303:NATPE_RS13565
uniprot id: L0JPY0
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

797303:NATPE RS07145
gene id: 797303:NATPE_RS07145
uniprot id: L0JLD9
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05040
gene id: 797303:NATPE_RS05040
uniprot id: L0JHE8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

797303:NATPE RS01560
gene id: 797303:NATPE_RS01560
uniprot id: L0JFE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS01705
gene id: 797303:NATPE_RS01705
uniprot id: L0JFK7
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS09895
gene id: 797303:NATPE_RS09895
uniprot id: L0JNJ9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

797303:NATPE RS08930
gene id: 797303:NATPE_RS08930
uniprot id: L0JLN0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS07080
gene id: 797303:NATPE_RS07080
uniprot id: L0JKL4
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS16175
gene id: 797303:NATPE_RS16175
uniprot id: L0JNU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

797303:NATPE RS16820
gene id: 797303:NATPE_RS16820
uniprot id: L0JP87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797303:NATPE RS14165
gene id: 797303:NATPE_RS14165
uniprot id: L0JPN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS13460
gene id: 797303:NATPE_RS13460
uniprot id: L9YJB7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04260
gene id: 797303:NATPE_RS04260
uniprot id: L0JHM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

797303:NATPE RS06830
gene id: 797303:NATPE_RS06830
uniprot id: L0JKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

797303:NATPE RS17525
gene id: 797303:NATPE_RS17525
uniprot id: L9YAS2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS20765
gene id: 797303:NATPE_RS20765
uniprot id: L0JS99
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS02370
gene id: 797303:NATPE_RS02370
uniprot id: L0JIN2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS17925
gene id: 797303:NATPE_RS17925
uniprot id: L0JRT5
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

797303:NATPE RS19775
gene id: 797303:NATPE_RS19775
uniprot id: L0JSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

797303:NATPE RS12600
gene id: 797303:NATPE_RS12600
uniprot id: L0JNS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

797303:NATPE RS13080
gene id: 797303:NATPE_RS13080
uniprot id: L0JQB1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

797303:NATPE RS04725
gene id: 797303:NATPE_RS04725
uniprot id: L0JJ74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

797303:NATPE RS17405
gene id: 797303:NATPE_RS17405
uniprot id: L0JRJ6
names: Subcellular Location Annotation
messages: Nucleus

797303:NATPE RS12665
gene id: 797303:NATPE_RS12665
uniprot id: L0JPG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS01815
gene id: 797303:NATPE_RS01815
uniprot id: L0JHJ7
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797303:NATPE RS04245
gene id: 797303:NATPE_RS04245
uniprot id: L0JKC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

797303:NATPE RS18975
gene id: 797303:NATPE_RS18975
uniprot id: L0JTM6
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS11840
gene id: 797303:NATPE_RS11840
uniprot id: L0JM52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797303:NATPE RS13270
gene id: 797303:NATPE_RS13270
uniprot id: L0JP37
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797303:NATPE RS12440
gene id: 797303:NATPE_RS12440
uniprot id: L0JPZ1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

797303:NATPE RS11025
gene id: 797303:NATPE_RS11025
uniprot id: L0JLK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

797303:NATPE RS20760
gene id: 797303:NATPE_RS20760
uniprot id: L0JTI3
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS15680
gene id: 797303:NATPE_RS15680
uniprot id: L0JRU4
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

797303:NATPE RS13490
gene id: 797303:NATPE_RS13490
uniprot id: L0JPW8
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

797303:NATPE RS04265
gene id: 797303:NATPE_RS04265
uniprot id: L0JH08
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

797303:NATPE RS01480
gene id: 797303:NATPE_RS01480
uniprot id: L0JFD1
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS04395
gene id: 797303:NATPE_RS04395
uniprot id: L0JKE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

797303:NATPE RS11330
gene id: 797303:NATPE_RS11330
uniprot id: L0JPE5
names: Similarity
messages: Belongs to the CutA family.

797303:NATPE RS17080
gene id: 797303:NATPE_RS17080
uniprot id: L0JQ82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

797303:NATPE RS08760
gene id: 797303:NATPE_RS08760
uniprot id: L0JJK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

797303:NATPE RS07555
gene id: 797303:NATPE_RS07555
uniprot id: L0JJM1
names: Similarity
messages: Belongs to the peptidase S8 family.

797303:NATPE RS04355
gene id: 797303:NATPE_RS04355
uniprot id: L0JJ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

797303:NATPE RS04635
gene id: 797303:NATPE_RS04635
uniprot id: L0JHU8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

797303:NATPE RS03780
gene id: 797303:NATPE_RS03780
uniprot id: L0JHA3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS15505
gene id: 797303:NATPE_RS15505
uniprot id: L0JP90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

797303:NATPE RS07740
gene id: 797303:NATPE_RS07740
uniprot id: L0JKZ0
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

797303:NATPE RS16220
gene id: 797303:NATPE_RS16220
uniprot id: L9YC02
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17280
gene id: 797303:NATPE_RS17280
uniprot id: L0JS13
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05825
gene id: 797303:NATPE_RS05825
uniprot id: L0JL77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

797303:NATPE RS10165
gene id: 797303:NATPE_RS10165
uniprot id: L0JL46
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797303:NATPE RS15645
gene id: 797303:NATPE_RS15645
uniprot id: L0JPB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

797303:NATPE RS00860
gene id: 797303:NATPE_RS00860
uniprot id: L0JIF0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

797303:NATPE RS20725
gene id: 797303:NATPE_RS20725
uniprot id: L0JS88
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS13155
gene id: 797303:NATPE_RS13155
uniprot id: L0JQC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

797303:NATPE RS07465
gene id: 797303:NATPE_RS07465
uniprot id: L0JIV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS17845
gene id: 797303:NATPE_RS17845
uniprot id: L0JSB0
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

797303:NATPE RS01685
gene id: 797303:NATPE_RS01685
uniprot id: L0JIZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

797303:NATPE RS18040
gene id: 797303:NATPE_RS18040
uniprot id: L0JSE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

797303:NATPE RS11020
gene id: 797303:NATPE_RS11020
uniprot id: L0JMU1
names: Similarity
messages: Belongs to the isochorismate synthase family.

797303:NATPE RS07605
gene id: 797303:NATPE_RS07605
uniprot id: L0JJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797303:NATPE RS11105
gene id: 797303:NATPE_RS11105
uniprot id: L0JLM2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

797303:NATPE RS04495
gene id: 797303:NATPE_RS04495
uniprot id: L0JKG5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797303:NATPE RS07875
gene id: 797303:NATPE_RS07875
uniprot id: L0JL17
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797303:NATPE RS08420
gene id: 797303:NATPE_RS08420
uniprot id: L0JMP0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS09415
gene id: 797303:NATPE_RS09415
uniprot id: L0JMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS10690
gene id: 797303:NATPE_RS10690
uniprot id: L0JNC9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS05010
gene id: 797303:NATPE_RS05010
uniprot id: L0JI18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

797303:NATPE RS14170
gene id: 797303:NATPE_RS14170
uniprot id: L0JNI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797303:NATPE RS11210
gene id: 797303:NATPE_RS11210
uniprot id: L0JKZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

797303:NATPE RS03280
gene id: 797303:NATPE_RS03280
uniprot id: L0JH04
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS10985
gene id: 797303:NATPE_RS10985
uniprot id: L0JP64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797303:NATPE RS13935
gene id: 797303:NATPE_RS13935
uniprot id: L0JQU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

797303:NATPE RS00560
gene id: 797303:NATPE_RS00560
uniprot id: L0JI99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS05945
gene id: 797303:NATPE_RS05945
uniprot id: L0JHX7
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

797303:NATPE RS11435
gene id: 797303:NATPE_RS11435
uniprot id: L0JL43
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

797303:NATPE RS00985
gene id: 797303:NATPE_RS00985
uniprot id: L0JF29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

797303:NATPE RS15605
gene id: 797303:NATPE_RS15605
uniprot id: L0JNI0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797303:NATPE RS12180
gene id: 797303:NATPE_RS12180
uniprot id: L9YKF8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS20665
gene id: 797303:NATPE_RS20665
uniprot id: L0JS78
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS15175
gene id: 797303:NATPE_RS15175
uniprot id: L0JQV1
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

797303:NATPE RS00810
gene id: 797303:NATPE_RS00810
uniprot id: L0JIE0
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS17625
gene id: 797303:NATPE_RS17625
uniprot id: L0JSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

797303:NATPE RS01805
gene id: 797303:NATPE_RS01805
uniprot id: L0JJ08
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797303:NATPE RS20990
gene id: 797303:NATPE_RS20990
uniprot id: L0JJW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

797303:NATPE RS11260
gene id: 797303:NATPE_RS11260
uniprot id: L0JL04
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS04835
gene id: 797303:NATPE_RS04835
uniprot id: L0JKM1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

797303:NATPE RS01875
gene id: 797303:NATPE_RS01875
uniprot id: L9Z0S0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS00750
gene id: 797303:NATPE_RS00750
uniprot id: L0JFL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

797303:NATPE RS05320
gene id: 797303:NATPE_RS05320
uniprot id: L0JKA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

797303:NATPE RS11815
gene id: 797303:NATPE_RS11815
uniprot id: L0JND1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

797303:NATPE RS11440
gene id: 797303:NATPE_RS11440
uniprot id: L0JPG5
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS10540
gene id: 797303:NATPE_RS10540
uniprot id: L0JKJ9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797303:NATPE RS15705
gene id: 797303:NATPE_RS15705
uniprot id: L0JR47
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

797303:NATPE RS07480
gene id: 797303:NATPE_RS07480
uniprot id: L0JKT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS16300
gene id: 797303:NATPE_RS16300
uniprot id: L0JPQ7
names: Similarity
messages: Belongs to the thioesterase PaaI family.

797303:NATPE RS08660
gene id: 797303:NATPE_RS08660
uniprot id: L0JMT7
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

797303:NATPE RS01700
gene id: 797303:NATPE_RS01700
uniprot id: L0JG72
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

797303:NATPE RS09115
gene id: 797303:NATPE_RS09115
uniprot id: L9YHV4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS09975
gene id: 797303:NATPE_RS09975
uniprot id: L9YW31
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04925
gene id: 797303:NATPE_RS04925
uniprot id: L0JK25
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

797303:NATPE RS06120
gene id: 797303:NATPE_RS06120
uniprot id: L0JKR8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797303:NATPE RS02130
gene id: 797303:NATPE_RS02130
uniprot id: L0JFS8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS07965
gene id: 797303:NATPE_RS07965
uniprot id: L0JMF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

797303:NATPE RS03985
gene id: 797303:NATPE_RS03985
uniprot id: L0JIR4
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS01550
gene id: 797303:NATPE_RS01550
uniprot id: L0JI65
names: Similarity
messages: Belongs to the UPF0146 family.

797303:NATPE RS17540
gene id: 797303:NATPE_RS17540
uniprot id: L0JPL6
names: Similarity
messages: Belongs to the threonine aldolase family.

797303:NATPE RS06015
gene id: 797303:NATPE_RS06015
uniprot id: L0JHZ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS15790
gene id: 797303:NATPE_RS15790
uniprot id: L0JPF8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

797303:NATPE RS00620
gene id: 797303:NATPE_RS00620
uniprot id: L9YB12
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04780
gene id: 797303:NATPE_RS04780
uniprot id: L9Z2W7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

797303:NATPE RS13425
gene id: 797303:NATPE_RS13425
uniprot id: L0JP61
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797303:NATPE RS12670
gene id: 797303:NATPE_RS12670
uniprot id: L0JNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797303:NATPE RS02675
gene id: 797303:NATPE_RS02675
uniprot id: L0JI07
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

797303:NATPE RS13175
gene id: 797303:NATPE_RS13175
uniprot id: L0JM28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

797303:NATPE RS07425
gene id: 797303:NATPE_RS07425
uniprot id: L9Z7U6
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17730
gene id: 797303:NATPE_RS17730
uniprot id: L0JS86
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

797303:NATPE RS11100
gene id: 797303:NATPE_RS11100
uniprot id: L0JMV7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

797303:NATPE RS07435
gene id: 797303:NATPE_RS07435
uniprot id: L0JKS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

797303:NATPE RS17950
gene id: 797303:NATPE_RS17950
uniprot id: L0JRU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

797303:NATPE RS10900
gene id: 797303:NATPE_RS10900
uniprot id: L9YTH6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS04145
gene id: 797303:NATPE_RS04145
uniprot id: L0JJK6
names: Subcellular Location Annotation
messages: Cytoplasm

797303:NATPE RS00525
gene id: 797303:NATPE_RS00525
uniprot id: L0JET2
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

797303:NATPE RS04305
gene id: 797303:NATPE_RS04305
uniprot id: L0JIZ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

797303:NATPE RS09185
gene id: 797303:NATPE_RS09185
uniprot id: L0JML2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS13530
gene id: 797303:NATPE_RS13530
uniprot id: L0JMA7
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS13280
gene id: 797303:NATPE_RS13280
uniprot id: L0JM54
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

797303:NATPE RS04345
gene id: 797303:NATPE_RS04345
uniprot id: L0JKD7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

797303:NATPE RS17460
gene id: 797303:NATPE_RS17460
uniprot id: L0JRK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS18390
gene id: 797303:NATPE_RS18390
uniprot id: L0JQ29
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS18520
gene id: 797303:NATPE_RS18520
uniprot id: L9Y2G8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS10775
gene id: 797303:NATPE_RS10775
uniprot id: L0JLF6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

797303:NATPE RS05305
gene id: 797303:NATPE_RS05305
uniprot id: L0JI76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797303:NATPE RS00850
gene id: 797303:NATPE_RS00850
uniprot id: L0JFN4
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS20050
gene id: 797303:NATPE_RS20050
uniprot id: L0JTL8
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS13000
gene id: 797303:NATPE_RS13000
uniprot id: L0JLZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS13020
gene id: 797303:NATPE_RS13020
uniprot id: L0JMR8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS00160
gene id: 797303:NATPE_RS00160
uniprot id: L0JEM6
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS10715
gene id: 797303:NATPE_RS10715
uniprot id: L0JND4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

797303:NATPE RS07475
gene id: 797303:NATPE_RS07475
uniprot id: L0JLK1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

797303:NATPE RS16120
gene id: 797303:NATPE_RS16120
uniprot id: L0JPN0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS02815
gene id: 797303:NATPE_RS02815
uniprot id: L0JG42
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS06635
gene id: 797303:NATPE_RS06635
uniprot id: L0JLR5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

797303:NATPE RS01180
gene id: 797303:NATPE_RS01180
uniprot id: L0JH39
names: Similarity
messages: Belongs to the SUI1 family.

797303:NATPE RS15550
gene id: 797303:NATPE_RS15550
uniprot id: L0JP99
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

797303:NATPE RS07725
gene id: 797303:NATPE_RS07725
uniprot id: L0JIZ1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797303:NATPE RS04080
gene id: 797303:NATPE_RS04080
uniprot id: L0JIT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS16950
gene id: 797303:NATPE_RS16950
uniprot id: L0JQ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797303:NATPE RS11585
gene id: 797303:NATPE_RS11585
uniprot id: L0JNV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

797303:NATPE RS12300
gene id: 797303:NATPE_RS12300
uniprot id: L0JNL7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS12050
gene id: 797303:NATPE_RS12050
uniprot id: L0JM89
names: Similarity
messages: Belongs to the UPF0179 family.

797303:NATPE RS17070
gene id: 797303:NATPE_RS17070
uniprot id: L0JRY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797303:NATPE RS01770
gene id: 797303:NATPE_RS01770
uniprot id: L0JG90
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS15270
gene id: 797303:NATPE_RS15270
uniprot id: L0JQX0
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

797303:NATPE RS06485
gene id: 797303:NATPE_RS06485
uniprot id: L0JL00
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS05340
gene id: 797303:NATPE_RS05340
uniprot id: L0JKY1
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05935
gene id: 797303:NATPE_RS05935
uniprot id: L0JJW4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

797303:NATPE RS14740
gene id: 797303:NATPE_RS14740
uniprot id: L0JNU4
names: Function
messages: Part of a potassium transport system.

797303:NATPE RS18605
gene id: 797303:NATPE_RS18605
uniprot id: L9Y3A0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS17735
gene id: 797303:NATPE_RS17735
uniprot id: L0JRQ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

797303:NATPE RS11080
gene id: 797303:NATPE_RS11080
uniprot id: L0JLL7
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS01990
gene id: 797303:NATPE_RS01990
uniprot id: L0JHN1
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS18460
gene id: 797303:NATPE_RS18460
uniprot id: L0JQX6
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797303:NATPE RS13850
gene id: 797303:NATPE_RS13850
uniprot id: L0JN92
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

797303:NATPE RS04075
gene id: 797303:NATPE_RS04075
uniprot id: L0JJJ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS00885
gene id: 797303:NATPE_RS00885
uniprot id: L0JIF4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

797303:NATPE RS03040
gene id: 797303:NATPE_RS03040
uniprot id: L0JG78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

797303:NATPE RS09700
gene id: 797303:NATPE_RS09700
uniprot id: L0JNG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS14265
gene id: 797303:NATPE_RS14265
uniprot id: L0JNK7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

797303:NATPE RS09025
gene id: 797303:NATPE_RS09025
uniprot id: L0JN19
names: Similarity
messages: Belongs to the peptidase S8 family.

797303:NATPE RS06440
gene id: 797303:NATPE_RS06440
uniprot id: L0JK73
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS04910
gene id: 797303:NATPE_RS04910
uniprot id: L0JI00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

797303:NATPE RS11425
gene id: 797303:NATPE_RS11425
uniprot id: L0JN33
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797303:NATPE RS17470
gene id: 797303:NATPE_RS17470
uniprot id: L0JPK2
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

797303:NATPE RS06405
gene id: 797303:NATPE_RS06405
uniprot id: L0JLK4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS09635
gene id: 797303:NATPE_RS09635
uniprot id: L0JK35
names: Similarity
messages: Belongs to the peptidase S1C family.

797303:NATPE RS17225
gene id: 797303:NATPE_RS17225
uniprot id: L0JSQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

797303:NATPE RS06785
gene id: 797303:NATPE_RS06785
uniprot id: L0JJ57
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

797303:NATPE RS02990
gene id: 797303:NATPE_RS02990
uniprot id: L0JG69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797303:NATPE RS01395
gene id: 797303:NATPE_RS01395
uniprot id: L0JH90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS01740
gene id: 797303:NATPE_RS01740
uniprot id: L0JIC7
names: Similarity
messages: Belongs to the PdaD family.

797303:NATPE RS20375
gene id: 797303:NATPE_RS20375
uniprot id: L0JR96
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

797303:NATPE RS06260
gene id: 797303:NATPE_RS06260
uniprot id: L0JLH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS03605
gene id: 797303:NATPE_RS03605
uniprot id: L0JII1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

797303:NATPE RS16900
gene id: 797303:NATPE_RS16900
uniprot id: L0JQ54
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS00170
gene id: 797303:NATPE_RS00170
uniprot id: L0JHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797303:NATPE RS11240
gene id: 797303:NATPE_RS11240
uniprot id: L0JPC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

797303:NATPE RS11695
gene id: 797303:NATPE_RS11695
uniprot id: L9YKK5
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS03305
gene id: 797303:NATPE_RS03305
uniprot id: L0JH10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

797303:NATPE RS16990
gene id: 797303:NATPE_RS16990
uniprot id: L0JRW9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797303:NATPE RS05685
gene id: 797303:NATPE_RS05685
uniprot id: L0JJS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

797303:NATPE RS04290
gene id: 797303:NATPE_RS04290
uniprot id: L0JH14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

797303:NATPE RS08405
gene id: 797303:NATPE_RS08405
uniprot id: L0JLB3
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

797303:NATPE RS15320
gene id: 797303:NATPE_RS15320
uniprot id: L0JQX8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

797303:NATPE RS07750
gene id: 797303:NATPE_RS07750
uniprot id: L0JIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

797303:NATPE RS05820
gene id: 797303:NATPE_RS05820
uniprot id: L0JHV2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS05795
gene id: 797303:NATPE_RS05795
uniprot id: L0JIG2
names: Similarity
messages: Belongs to the UPF0212 family.

797303:NATPE RS10320
gene id: 797303:NATPE_RS10320
uniprot id: L0JKF7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

797303:NATPE RS07990
gene id: 797303:NATPE_RS07990
uniprot id: L9YI31
names: Caution
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS10060
gene id: 797303:NATPE_RS10060
uniprot id: L0JKB2
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS00625
gene id: 797303:NATPE_RS00625
uniprot id: L0JFI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

797303:NATPE RS01690
gene id: 797303:NATPE_RS01690
uniprot id: L0JIB2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797303:NATPE RS10670
gene id: 797303:NATPE_RS10670
uniprot id: L0JLD6
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797303:NATPE RS02065
gene id: 797303:NATPE_RS02065
uniprot id: L9YYU2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14040
gene id: 797303:NATPE_RS14040
uniprot id: L9YQM8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS07000
gene id: 797303:NATPE_RS07000
uniprot id: L0JLB2
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

797303:NATPE RS17450
gene id: 797303:NATPE_RS17450
uniprot id: L0JST8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

797303:NATPE RS08065
gene id: 797303:NATPE_RS08065
uniprot id: L0JJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797303:NATPE RS15305
gene id: 797303:NATPE_RS15305
uniprot id: L0JP48
names: Similarity
messages: Belongs to the Nudix hydrolase family.

797303:NATPE RS15400
gene id: 797303:NATPE_RS15400
uniprot id: L9YCZ1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS10725
gene id: 797303:NATPE_RS10725
uniprot id: L0JLE5
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

797303:NATPE RS04560
gene id: 797303:NATPE_RS04560
uniprot id: L9Z2L9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS07205
gene id: 797303:NATPE_RS07205
uniprot id: L9Z6T1
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS03635
gene id: 797303:NATPE_RS03635
uniprot id: L0JGK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797303:NATPE RS09085
gene id: 797303:NATPE_RS09085
uniprot id: L0JN30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797303:NATPE RS06130
gene id: 797303:NATPE_RS06130
uniprot id: L0JIN3
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS11775
gene id: 797303:NATPE_RS11775
uniprot id: L0JM40
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS05165
gene id: 797303:NATPE_RS05165
uniprot id: L0JKU1
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS11090
gene id: 797303:NATPE_RS11090
uniprot id: L9YVK8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14875
gene id: 797303:NATPE_RS14875
uniprot id: L0JQ36
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

797303:NATPE RS17335
gene id: 797303:NATPE_RS17335
uniprot id: L0JRI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

797303:NATPE RS11305
gene id: 797303:NATPE_RS11305
uniprot id: L0JPD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

797303:NATPE RS03030
gene id: 797303:NATPE_RS03030
uniprot id: L9YWM2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS14845
gene id: 797303:NATPE_RS14845
uniprot id: L0JRD0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS10790
gene id: 797303:NATPE_RS10790
uniprot id: L0JNE7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

797303:NATPE RS07130
gene id: 797303:NATPE_RS07130
uniprot id: L0JKM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

797303:NATPE RS18180
gene id: 797303:NATPE_RS18180
uniprot id: L0JRY9
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

797303:NATPE RS04480
gene id: 797303:NATPE_RS04480
uniprot id: L0JJ28
names: Similarity
messages: Belongs to the thioesterase PaaI family.

797303:NATPE RS05265
gene id: 797303:NATPE_RS05265
uniprot id: L9Z400
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS15875
gene id: 797303:NATPE_RS15875
uniprot id: L0JR79
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

797303:NATPE RS01800
gene id: 797303:NATPE_RS01800
uniprot id: L0JFM4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

797303:NATPE RS08195
gene id: 797303:NATPE_RS08195
uniprot id: L0JL75
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

797303:NATPE RS02135
gene id: 797303:NATPE_RS02135
uniprot id: L0JJ64
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS08890
gene id: 797303:NATPE_RS08890
uniprot id: L0JKD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

797303:NATPE RS14245
gene id: 797303:NATPE_RS14245
uniprot id: L0JNK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

797303:NATPE RS08130
gene id: 797303:NATPE_RS08130
uniprot id: L0JLX0
names: Subcellular Location Annotation
messages: Membrane

797303:NATPE RS16650
gene id: 797303:NATPE_RS16650
uniprot id: L0JP57
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797303:NATPE RS12975
gene id: 797303:NATPE_RS12975
uniprot id: L0JLY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

797303:NATPE RS20035
gene id: 797303:NATPE_RS20035
uniprot id: L9Y507
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS18070
gene id: 797303:NATPE_RS18070
uniprot id: L9Y9C1
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

797303:NATPE RS00640
gene id: 797303:NATPE_RS00640
uniprot id: L0JGU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

797303:NATPE RS05380
gene id: 797303:NATPE_RS05380
uniprot id: L0JKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

797303:NATPE RS17095
gene id: 797303:NATPE_RS17095
uniprot id: L0JRY6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

797303:NATPE RS08385
gene id: 797303:NATPE_RS08385
uniprot id: L0JK37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797303:NATPE RS01055
gene id: 797303:NATPE_RS01055
uniprot id: L0JFS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

797303:NATPE RS10455
gene id: 797303:NATPE_RS10455
uniprot id: L0JMI8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

797303:NATPE RS08070
gene id: 797303:NATPE_RS08070
uniprot id: L0JJ56
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

797303:NATPE RS08150
gene id: 797303:NATPE_RS08150
uniprot id: L0JMJ1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.