797210:HALXA RS16230
gene id: 797210:HALXA_RS16230
uniprot id: F8D3U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS18530
gene id: 797210:HALXA_RS18530
uniprot id: F8DDH0
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

797210:HALXA RS07990
gene id: 797210:HALXA_RS07990
uniprot id: F8DA11
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS08270
gene id: 797210:HALXA_RS08270
uniprot id: F8DAQ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS16150
gene id: 797210:HALXA_RS16150
uniprot id: F8D3S5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

797210:HALXA RS09700
gene id: 797210:HALXA_RS09700
uniprot id: F8DCU8
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797210:HALXA RS11865
gene id: 797210:HALXA_RS11865
uniprot id: F8D5Z3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS12800
gene id: 797210:HALXA_RS12800
uniprot id: F8D820
names: Similarity
messages: Belongs to the isochorismate synthase family.

797210:HALXA RS06285
gene id: 797210:HALXA_RS06285
uniprot id: F8D6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

797210:HALXA RS09005
gene id: 797210:HALXA_RS09005
uniprot id: F8DC24
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797210:HALXA RS20260
gene id: 797210:HALXA_RS20260
uniprot id: F8DEG2
names: Similarity
messages: Belongs to the SCO1/2 family.

797210:HALXA RS08670
gene id: 797210:HALXA_RS08670
uniprot id: F8DBF5
names: Similarity
messages: Belongs to the HypE family.

797210:HALXA RS12175
gene id: 797210:HALXA_RS12175
uniprot id: F8D6P3
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

797210:HALXA RS01630
gene id: 797210:HALXA_RS01630
uniprot id: F8D955
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797210:HALXA RS13400
gene id: 797210:HALXA_RS13400
uniprot id: F8D8W0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797210:HALXA RS04145
gene id: 797210:HALXA_RS04145
uniprot id: F8D3E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

797210:HALXA RS03860
gene id: 797210:HALXA_RS03860
uniprot id: F8D2W3
names: Similarity
messages: Belongs to the alkaline phosphatase family.

797210:HALXA RS01815
gene id: 797210:HALXA_RS01815
uniprot id: F8D984
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS14410
gene id: 797210:HALXA_RS14410
uniprot id: F8DAY5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

797210:HALXA RS05255
gene id: 797210:HALXA_RS05255
uniprot id: F8D7K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

797210:HALXA RS06970
gene id: 797210:HALXA_RS06970
uniprot id: F8D7Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
messages: In the N-terminal section; belongs to the KAE1 / TsaD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function.

797210:HALXA RS07655
gene id: 797210:HALXA_RS07655
uniprot id: F8D9C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

797210:HALXA RS16950
gene id: 797210:HALXA_RS16950
uniprot id: F8D4Y0
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS07545
gene id: 797210:HALXA_RS07545
uniprot id: F8D9A0
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS01665
gene id: 797210:HALXA_RS01665
uniprot id: F8D6S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

797210:HALXA RS15610
gene id: 797210:HALXA_RS15610
uniprot id: F8DB55
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS01600
gene id: 797210:HALXA_RS01600
uniprot id: F8D949
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

797210:HALXA RS07995
gene id: 797210:HALXA_RS07995
uniprot id: F8DA12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

797210:HALXA RS04415
gene id: 797210:HALXA_RS04415
uniprot id: F8D7I3
names: Similarity
messages: Belongs to the SUI1 family.

797210:HALXA RS04240
gene id: 797210:HALXA_RS04240
uniprot id: F8D3F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

797210:HALXA RS02305
gene id: 797210:HALXA_RS02305
uniprot id: F8DAI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

797210:HALXA RS04465
gene id: 797210:HALXA_RS04465
uniprot id: F8D3J6
names: Similarity
messages: Belongs to the selenium-binding protein family.

797210:HALXA RS05670
gene id: 797210:HALXA_RS05670
uniprot id: F8D5N9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

797210:HALXA RS15205
gene id: 797210:HALXA_RS15205
uniprot id: F8DCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS19160
gene id: 797210:HALXA_RS19160
uniprot id: F8DDT5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

797210:HALXA RS11500
gene id: 797210:HALXA_RS11500
uniprot id: F8D9R2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

797210:HALXA RS00260
gene id: 797210:HALXA_RS00260
uniprot id: F8D6C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797210:HALXA RS10430
gene id: 797210:HALXA_RS10430
uniprot id: F8D3Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

797210:HALXA RS01810
gene id: 797210:HALXA_RS01810
uniprot id: F8D983
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS13090
gene id: 797210:HALXA_RS13090
uniprot id: F8D870
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797210:HALXA RS18585
gene id: 797210:HALXA_RS18585
uniprot id: F8DDI1
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

797210:HALXA RS10825
gene id: 797210:HALXA_RS10825
uniprot id: F8D499
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797210:HALXA RS05485
gene id: 797210:HALXA_RS05485
uniprot id: F8D571
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS09230
gene id: 797210:HALXA_RS09230
uniprot id: F8D8Z6
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS17030
gene id: 797210:HALXA_RS17030
uniprot id: F8D4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

797210:HALXA RS08220
gene id: 797210:HALXA_RS08220
uniprot id: F8DAN9
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

797210:HALXA RS02455
gene id: 797210:HALXA_RS02455
uniprot id: F8DAL6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

797210:HALXA RS11920
gene id: 797210:HALXA_RS11920
uniprot id: F8D602
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS00010
gene id: 797210:HALXA_RS00010
uniprot id: F8D680
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS15460
gene id: 797210:HALXA_RS15460
uniprot id: F8DCX2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

797210:HALXA RS19705
gene id: 797210:HALXA_RS19705
uniprot id: F8DE26
names: Similarity
messages: Belongs to the PrpD family.

797210:HALXA RS10805
gene id: 797210:HALXA_RS10805
uniprot id: F8D495
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

797210:HALXA RS02310
gene id: 797210:HALXA_RS02310
uniprot id: F8DAI7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS13395
gene id: 797210:HALXA_RS13395
uniprot id: F8DAE1
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

797210:HALXA RS04190
gene id: 797210:HALXA_RS04190
uniprot id: F8D3E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

797210:HALXA RS16880
gene id: 797210:HALXA_RS16880
uniprot id: F8D4W6
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797210:HALXA RS15560
gene id: 797210:HALXA_RS15560
uniprot id: F8DCZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

797210:HALXA RS15150
gene id: 797210:HALXA_RS15150
uniprot id: F8DCC1
names: Similarity
messages: Belongs to the glycosyl hydrolase 67 family.

797210:HALXA RS13600
gene id: 797210:HALXA_RS13600
uniprot id: F8D9H8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797210:HALXA RS14305
gene id: 797210:HALXA_RS14305
uniprot id: F8DAW4
names: Similarity
messages: Belongs to the Dps family.

797210:HALXA RS01160
gene id: 797210:HALXA_RS01160
uniprot id: F8D8D8
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS07055
gene id: 797210:HALXA_RS07055
uniprot id: F8D7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797210:HALXA RS03685
gene id: 797210:HALXA_RS03685
uniprot id: F8DCM6
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS12070
gene id: 797210:HALXA_RS12070
uniprot id: F8D6M3
names: Function
names: Similarity
messages: Belongs to the archaeal-type GTP cyclohydrolase family.
messages: Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.

797210:HALXA RS13785
gene id: 797210:HALXA_RS13785
uniprot id: F8DAF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

797210:HALXA RS10250
gene id: 797210:HALXA_RS10250
uniprot id: F8D3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

797210:HALXA RS08545
gene id: 797210:HALXA_RS08545
uniprot id: F8DAV0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS10270
gene id: 797210:HALXA_RS10270
uniprot id: F8D3M9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

797210:HALXA RS00205
gene id: 797210:HALXA_RS00205
uniprot id: F8D6B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

797210:HALXA RS01190
gene id: 797210:HALXA_RS01190
uniprot id: F8D8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

797210:HALXA RS02980
gene id: 797210:HALXA_RS02980
uniprot id: F8DBD9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

797210:HALXA RS13795
gene id: 797210:HALXA_RS13795
uniprot id: F8DAF3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

797210:HALXA RS18330
gene id: 797210:HALXA_RS18330
uniprot id: F8DDD3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

797210:HALXA RS05535
gene id: 797210:HALXA_RS05535
uniprot id: F8D576
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes the NAD-dependent oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Homodimer.

797210:HALXA RS03225
gene id: 797210:HALXA_RS03225
uniprot id: F8DBZ9
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS11750
gene id: 797210:HALXA_RS11750
uniprot id: F8D5X0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS00715
gene id: 797210:HALXA_RS00715
uniprot id: F8D734
names: Similarity
messages: Belongs to the gas vesicle GvpA family.

797210:HALXA RS07170
gene id: 797210:HALXA_RS07170
uniprot id: F8D8K8
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS12235
gene id: 797210:HALXA_RS12235
uniprot id: F8D6Q2
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS12540
gene id: 797210:HALXA_RS12540
uniprot id: F8D7D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

797210:HALXA RS15990
gene id: 797210:HALXA_RS15990
uniprot id: F8D3B1
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

797210:HALXA RS20340
gene id: 797210:HALXA_RS20340
uniprot id: F8DEE0
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS03675
gene id: 797210:HALXA_RS03675
uniprot id: F8DCM4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS16900
gene id: 797210:HALXA_RS16900
uniprot id: F8D4W9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS19375
gene id: 797210:HALXA_RS19375
uniprot id: F8DE16
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS16220
gene id: 797210:HALXA_RS16220
uniprot id: F8D3T9
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS02285
gene id: 797210:HALXA_RS02285
uniprot id: F8DAI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

797210:HALXA RS03850
gene id: 797210:HALXA_RS03850
uniprot id: F8D2W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

797210:HALXA RS13045
gene id: 797210:HALXA_RS13045
uniprot id: F8D863
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS10075
gene id: 797210:HALXA_RS10075
uniprot id: F8D362
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

797210:HALXA RS05305
gene id: 797210:HALXA_RS05305
uniprot id: F8D538
names: Similarity
messages: Belongs to the serpin family.

797210:HALXA RS18435
gene id: 797210:HALXA_RS18435
uniprot id: F8DDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS07110
gene id: 797210:HALXA_RS07110
uniprot id: F8D8A1
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797210:HALXA RS17720
gene id: 797210:HALXA_RS17720
uniprot id: F8D638
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

797210:HALXA RS18720
gene id: 797210:HALXA_RS18720
uniprot id: F8DE10
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

797210:HALXA RS02270
gene id: 797210:HALXA_RS02270
uniprot id: F8DAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

797210:HALXA RS10210
gene id: 797210:HALXA_RS10210
uniprot id: F8D3L7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797210:HALXA RS03450
gene id: 797210:HALXA_RS03450
uniprot id: F8DCI0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

797210:HALXA RS06695
gene id: 797210:HALXA_RS06695
uniprot id: F8D794
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

797210:HALXA RS01040
gene id: 797210:HALXA_RS01040
uniprot id: F8D671
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS11915
gene id: 797210:HALXA_RS11915
uniprot id: F8D601
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797210:HALXA RS00605
gene id: 797210:HALXA_RS00605
uniprot id: F8D717
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS01850
gene id: 797210:HALXA_RS01850
uniprot id: F8D990
names: Similarity
messages: Belongs to the LarC family.

797210:HALXA RS08875
gene id: 797210:HALXA_RS08875
uniprot id: F8DBI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS02695
gene id: 797210:HALXA_RS02695
uniprot id: F8DB92
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS11860
gene id: 797210:HALXA_RS11860
uniprot id: F8D5Z2
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

797210:HALXA RS01670
gene id: 797210:HALXA_RS01670
uniprot id: F8D961
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

797210:HALXA RS00830
gene id: 797210:HALXA_RS00830
uniprot id: F8D7P7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

797210:HALXA RS01060
gene id: 797210:HALXA_RS01060
uniprot id: F8D7T6
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS12550
gene id: 797210:HALXA_RS12550
uniprot id: F8D7E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

797210:HALXA RS18875
gene id: 797210:HALXA_RS18875
uniprot id: F8DDN3
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS10220
gene id: 797210:HALXA_RS10220
uniprot id: F8D3L9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS05655
gene id: 797210:HALXA_RS05655
uniprot id: F8D5N6
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797210:HALXA RS12005
gene id: 797210:HALXA_RS12005
uniprot id: F8D6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

797210:HALXA RS13100
gene id: 797210:HALXA_RS13100
uniprot id: F8D872
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

797210:HALXA RS12620
gene id: 797210:HALXA_RS12620
uniprot id: F8D7F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

797210:HALXA RS01590
gene id: 797210:HALXA_RS01590
uniprot id: F8D947
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

797210:HALXA RS09715
gene id: 797210:HALXA_RS09715
uniprot id: F8DCV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS00230
gene id: 797210:HALXA_RS00230
uniprot id: F8D6C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Homodimer.

797210:HALXA RS16105
gene id: 797210:HALXA_RS16105
uniprot id: F8DB66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

797210:HALXA RS15920
gene id: 797210:HALXA_RS15920
uniprot id: F8D3A1
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

797210:HALXA RS07700
gene id: 797210:HALXA_RS07700
uniprot id: F8D9C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

797210:HALXA RS11115
gene id: 797210:HALXA_RS11115
uniprot id: F8D9Q1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS04645
gene id: 797210:HALXA_RS04645
uniprot id: F8D412
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS07245
gene id: 797210:HALXA_RS07245
uniprot id: F8D8M4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797210:HALXA RS11985
gene id: 797210:HALXA_RS11985
uniprot id: F8D6K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797210:HALXA RS07895
gene id: 797210:HALXA_RS07895
uniprot id: F8D9Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

797210:HALXA RS00860
gene id: 797210:HALXA_RS00860
uniprot id: F8D7Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

797210:HALXA RS13030
gene id: 797210:HALXA_RS13030
uniprot id: F8D861
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

797210:HALXA RS14705
gene id: 797210:HALXA_RS14705
uniprot id: F8DBL8
names: Similarity
messages: Belongs to the methylamine corrinoid protein family.

797210:HALXA RS11420
gene id: 797210:HALXA_RS11420
uniprot id: F8D5C9
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS11255
gene id: 797210:HALXA_RS11255
uniprot id: F8D595
names: Similarity
messages: Belongs to the catalase family.

797210:HALXA RS12725
gene id: 797210:HALXA_RS12725
uniprot id: F8D805
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

797210:HALXA RS17410
gene id: 797210:HALXA_RS17410
uniprot id: F8D5J6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

797210:HALXA RS02775
gene id: 797210:HALXA_RS02775
uniprot id: F8DBA8
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797210:HALXA RS00410
gene id: 797210:HALXA_RS00410
uniprot id: F8D6X5
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

797210:HALXA RS17020
gene id: 797210:HALXA_RS17020
uniprot id: F8D4Z3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

797210:HALXA RS16370
gene id: 797210:HALXA_RS16370
uniprot id: F8D3W2
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

797210:HALXA RS04735
gene id: 797210:HALXA_RS04735
uniprot id: F8D427
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.

797210:HALXA RS15515
gene id: 797210:HALXA_RS15515
uniprot id: F8DCY3
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS19140
gene id: 797210:HALXA_RS19140
uniprot id: F8DDT1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

797210:HALXA RS02660
gene id: 797210:HALXA_RS02660
uniprot id: F8DB85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797210:HALXA RS08905
gene id: 797210:HALXA_RS08905
uniprot id: F8DBJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
messages: Monomer and homodimer.

797210:HALXA RS12760
gene id: 797210:HALXA_RS12760
uniprot id: F8D812
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

797210:HALXA RS09170
gene id: 797210:HALXA_RS09170
uniprot id: F8DC59
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

797210:HALXA RS07030
gene id: 797210:HALXA_RS07030
uniprot id: F8D7Z3
names: Similarity
messages: Belongs to the HypE family.

797210:HALXA RS06745
gene id: 797210:HALXA_RS06745
uniprot id: F8D887
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS06005
gene id: 797210:HALXA_RS06005
uniprot id: F8D5U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

797210:HALXA RS02280
gene id: 797210:HALXA_RS02280
uniprot id: F8DAI0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

797210:HALXA RS17050
gene id: 797210:HALXA_RS17050
uniprot id: F8D4Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

797210:HALXA RS14765
gene id: 797210:HALXA_RS14765
uniprot id: F8DBN1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

797210:HALXA RS11945
gene id: 797210:HALXA_RS11945
uniprot id: F8D607
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

797210:HALXA RS08085
gene id: 797210:HALXA_RS08085
uniprot id: F8DA32
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS16400
gene id: 797210:HALXA_RS16400
uniprot id: F8D3W6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

797210:HALXA RS00360
gene id: 797210:HALXA_RS00360
uniprot id: F8D6D8
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

797210:HALXA RS05660
gene id: 797210:HALXA_RS05660
uniprot id: F8D5N7
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797210:HALXA RS03405
gene id: 797210:HALXA_RS03405
uniprot id: F8DCH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS09710
gene id: 797210:HALXA_RS09710
uniprot id: F8DCV0
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

797210:HALXA RS14875
gene id: 797210:HALXA_RS14875
uniprot id: F8DBQ3
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS02720
gene id: 797210:HALXA_RS02720
uniprot id: F8DB97
names: Similarity
messages: Belongs to the peptidase S8 family.

797210:HALXA RS19915
gene id: 797210:HALXA_RS19915
uniprot id: F8DE70
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS14835
gene id: 797210:HALXA_RS14835
uniprot id: F8DBP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

797210:HALXA RS15795
gene id: 797210:HALXA_RS15795
uniprot id: F8D376
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family. MfnA subfamily.
messages: Catalyzes the decarboxylation of L-aspartate to produce beta-alanine.

797210:HALXA RS10225
gene id: 797210:HALXA_RS10225
uniprot id: F8D3M0
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS08860
gene id: 797210:HALXA_RS08860
uniprot id: F8DBI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

797210:HALXA RS07830
gene id: 797210:HALXA_RS07830
uniprot id: F8D9F3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS13650
gene id: 797210:HALXA_RS13650
uniprot id: F8D9I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

797210:HALXA RS06070
gene id: 797210:HALXA_RS06070
uniprot id: F8D6F2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

797210:HALXA RS18615
gene id: 797210:HALXA_RS18615
uniprot id: F8DDI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS00570
gene id: 797210:HALXA_RS00570
uniprot id: F8D710
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

797210:HALXA RS14015
gene id: 797210:HALXA_RS14015
uniprot id: F8DA77
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

797210:HALXA RS14770
gene id: 797210:HALXA_RS14770
uniprot id: F8DBN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797210:HALXA RS17225
gene id: 797210:HALXA_RS17225
uniprot id: F8D527
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS05435
gene id: 797210:HALXA_RS05435
uniprot id: F8D564
names: Similarity
messages: Belongs to the MoaB/Mog family.

797210:HALXA RS15575
gene id: 797210:HALXA_RS15575
uniprot id: F8DCZ5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS10265
gene id: 797210:HALXA_RS10265
uniprot id: F8D3M8
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS19700
gene id: 797210:HALXA_RS19700
uniprot id: F8DE25
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

797210:HALXA RS01655
gene id: 797210:HALXA_RS01655
uniprot id: F8D6S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

797210:HALXA RS00220
gene id: 797210:HALXA_RS00220
uniprot id: F8D6C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS09115
gene id: 797210:HALXA_RS09115
uniprot id: F8DC48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

797210:HALXA RS02410
gene id: 797210:HALXA_RS02410
uniprot id: F8DAK7
names: Similarity
messages: Belongs to the IMPACT family.

797210:HALXA RS11770
gene id: 797210:HALXA_RS11770
uniprot id: F8D5X4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS01645
gene id: 797210:HALXA_RS01645
uniprot id: F8D958
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

797210:HALXA RS10715
gene id: 797210:HALXA_RS10715
uniprot id: F8D482
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

797210:HALXA RS15195
gene id: 797210:HALXA_RS15195
uniprot id: F8DCC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

797210:HALXA RS03425
gene id: 797210:HALXA_RS03425
uniprot id: F8DCH5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

797210:HALXA RS08525
gene id: 797210:HALXA_RS08525
uniprot id: F8DAU6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS04955
gene id: 797210:HALXA_RS04955
uniprot id: F8D4J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797210:HALXA RS12480
gene id: 797210:HALXA_RS12480
uniprot id: F8D7C9
names: Similarity
messages: Belongs to the peptidase S66 family.

797210:HALXA RS12195
gene id: 797210:HALXA_RS12195
uniprot id: F8D6P7
names: Similarity
messages: Belongs to the UPF0212 family.

797210:HALXA RS05550
gene id: 797210:HALXA_RS05550
uniprot id: F8D580
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

797210:HALXA RS11975
gene id: 797210:HALXA_RS11975
uniprot id: F8D9S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

797210:HALXA RS11430
gene id: 797210:HALXA_RS11430
uniprot id: F8D5D1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS16350
gene id: 797210:HALXA_RS16350
uniprot id: F8D3W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

797210:HALXA RS06820
gene id: 797210:HALXA_RS06820
uniprot id: F8D7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

797210:HALXA RS06475
gene id: 797210:HALXA_RS06475
uniprot id: F8D753
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

797210:HALXA RS10795
gene id: 797210:HALXA_RS10795
uniprot id: F8D494
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

797210:HALXA RS12405
gene id: 797210:HALXA_RS12405
uniprot id: F8D7B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

797210:HALXA RS06050
gene id: 797210:HALXA_RS06050
uniprot id: F8D6E8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

797210:HALXA RS07175
gene id: 797210:HALXA_RS07175
uniprot id: F8D8K9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797210:HALXA RS11690
gene id: 797210:HALXA_RS11690
uniprot id: F8D5V8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

797210:HALXA RS14425
gene id: 797210:HALXA_RS14425
uniprot id: F8DAY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecF.

797210:HALXA RS04850
gene id: 797210:HALXA_RS04850
uniprot id: F8D439
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

797210:HALXA RS15435
gene id: 797210:HALXA_RS15435
uniprot id: F8DCW8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

797210:HALXA RS15035
gene id: 797210:HALXA_RS15035
uniprot id: F8DC97
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS15320
gene id: 797210:HALXA_RS15320
uniprot id: F8DCF2
names: Subcellular Location Annotation
messages: Nucleus

797210:HALXA RS18445
gene id: 797210:HALXA_RS18445
uniprot id: F8DDF3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS12295
gene id: 797210:HALXA_RS12295
uniprot id: F8D6R1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

797210:HALXA RS03070
gene id: 797210:HALXA_RS03070
uniprot id: F8DBW6
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS07195
gene id: 797210:HALXA_RS07195
uniprot id: F8D8L4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

797210:HALXA RS16060
gene id: 797210:HALXA_RS16060
uniprot id: F8D3C2
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS02915
gene id: 797210:HALXA_RS02915
uniprot id: F8D6V3
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

797210:HALXA RS01140
gene id: 797210:HALXA_RS01140
uniprot id: F8D8D4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

797210:HALXA RS10440
gene id: 797210:HALXA_RS10440
uniprot id: F8D3Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

797210:HALXA RS08845
gene id: 797210:HALXA_RS08845
uniprot id: F8D8Y8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

797210:HALXA RS06800
gene id: 797210:HALXA_RS06800
uniprot id: F8D7V2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS13375
gene id: 797210:HALXA_RS13375
uniprot id: F8D8V7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

797210:HALXA RS04170
gene id: 797210:HALXA_RS04170
uniprot id: F8D3E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

797210:HALXA RS14445
gene id: 797210:HALXA_RS14445
uniprot id: F8DAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

797210:HALXA RS01100
gene id: 797210:HALXA_RS01100
uniprot id: F8D8C6
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.

797210:HALXA RS17725
gene id: 797210:HALXA_RS17725
uniprot id: F8D639
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

797210:HALXA RS05645
gene id: 797210:HALXA_RS05645
uniprot id: F8D5N4
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS10780
gene id: 797210:HALXA_RS10780
uniprot id: F8D491
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MRE11/RAD32 family.
messages: Binds 2 manganese ions per subunit.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nuclease activity is regulated by Rad50.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.

797210:HALXA RS03360
gene id: 797210:HALXA_RS03360
uniprot id: F8DCG2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

797210:HALXA RS17380
gene id: 797210:HALXA_RS17380
uniprot id: F8D5J0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

797210:HALXA RS09800
gene id: 797210:HALXA_RS09800
uniprot id: F8D314
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

797210:HALXA RS19205
gene id: 797210:HALXA_RS19205
uniprot id: F8DDU3
names: Similarity
messages: Belongs to the AOR/FOR family.

797210:HALXA RS12560
gene id: 797210:HALXA_RS12560
uniprot id: F8D7E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane

797210:HALXA RS03030
gene id: 797210:HALXA_RS03030
uniprot id: F8DBV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

797210:HALXA RS13970
gene id: 797210:HALXA_RS13970
uniprot id: F8DA68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

797210:HALXA RS07975
gene id: 797210:HALXA_RS07975
uniprot id: F8DA08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS06370
gene id: 797210:HALXA_RS06370
uniprot id: F8D6K3
names: Similarity
messages: Belongs to the citrate synthase family.

797210:HALXA RS04350
gene id: 797210:HALXA_RS04350
uniprot id: F8D3I0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

797210:HALXA RS03275
gene id: 797210:HALXA_RS03275
uniprot id: F8DC09
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

797210:HALXA RS18095
gene id: 797210:HALXA_RS18095
uniprot id: F8DD86
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

797210:HALXA RS05840
gene id: 797210:HALXA_RS05840
uniprot id: F8D5S1
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

797210:HALXA RS15430
gene id: 797210:HALXA_RS15430
uniprot id: F8DCW7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

797210:HALXA RS01635
gene id: 797210:HALXA_RS01635
uniprot id: F8D956
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

797210:HALXA RS20290
gene id: 797210:HALXA_RS20290
uniprot id: F8DEG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS10150
gene id: 797210:HALXA_RS10150
uniprot id: F8D3K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

797210:HALXA RS08370
gene id: 797210:HALXA_RS08370
uniprot id: F8DAR9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

797210:HALXA RS08445
gene id: 797210:HALXA_RS08445
uniprot id: F8DAT3
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS07005
gene id: 797210:HALXA_RS07005
uniprot id: F8D893
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

797210:HALXA RS07295
gene id: 797210:HALXA_RS07295
uniprot id: F8D8N3
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS07100
gene id: 797210:HALXA_RS07100
uniprot id: F8D802
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS14775
gene id: 797210:HALXA_RS14775
uniprot id: F8DBN3
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

797210:HALXA RS17655
gene id: 797210:HALXA_RS17655
uniprot id: F8D626
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

797210:HALXA RS06075
gene id: 797210:HALXA_RS06075
uniprot id: F8D6F3
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS15025
gene id: 797210:HALXA_RS15025
uniprot id: F8DC95
names: Similarity
messages: Belongs to the peptidase S9C family.

797210:HALXA RS11990
gene id: 797210:HALXA_RS11990
uniprot id: F8D6K7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

797210:HALXA RS18970
gene id: 797210:HALXA_RS18970
uniprot id: F8DDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797210:HALXA RS10080
gene id: 797210:HALXA_RS10080
uniprot id: F8D363
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

797210:HALXA RS06935
gene id: 797210:HALXA_RS06935
uniprot id: F8D889
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cell membrane
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Membrane
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

797210:HALXA RS19200
gene id: 797210:HALXA_RS19200
uniprot id: F8DDU2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797210:HALXA RS05205
gene id: 797210:HALXA_RS05205
uniprot id: F8D4N8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS07330
gene id: 797210:HALXA_RS07330
uniprot id: F8D8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

797210:HALXA RS01570
gene id: 797210:HALXA_RS01570
uniprot id: F8D943
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

797210:HALXA RS16030
gene id: 797210:HALXA_RS16030
uniprot id: F8D3B7
names: Function
messages: Part of a potassium transport system.

797210:HALXA RS11400
gene id: 797210:HALXA_RS11400
uniprot id: F8D5C6
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS05225
gene id: 797210:HALXA_RS05225
uniprot id: F8D4P0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

797210:HALXA RS12675
gene id: 797210:HALXA_RS12675
uniprot id: F8D7G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

797210:HALXA RS18510
gene id: 797210:HALXA_RS18510
uniprot id: F8DDG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

797210:HALXA RS20195
gene id: 797210:HALXA_RS20195
uniprot id: F8DEB7
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS04680
gene id: 797210:HALXA_RS04680
uniprot id: F8D419
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797210:HALXA RS15325
gene id: 797210:HALXA_RS15325
uniprot id: F8DCF3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

797210:HALXA RS15480
gene id: 797210:HALXA_RS15480
uniprot id: F8DCX6
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS00710
gene id: 797210:HALXA_RS00710
uniprot id: F8D733
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

797210:HALXA RS07970
gene id: 797210:HALXA_RS07970
uniprot id: F8DA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS14490
gene id: 797210:HALXA_RS14490
uniprot id: F8DB26
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS11905
gene id: 797210:HALXA_RS11905
uniprot id: F8D5Z9
names: Similarity
messages: Belongs to the GARS family.

797210:HALXA RS17845
gene id: 797210:HALXA_RS17845
uniprot id: F8DD35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS16890
gene id: 797210:HALXA_RS16890
uniprot id: F8D4W8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

797210:HALXA RS03215
gene id: 797210:HALXA_RS03215
uniprot id: F8DBZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

797210:HALXA RS12715
gene id: 797210:HALXA_RS12715
uniprot id: F8D7G8
names: Subunit
messages: Homotrimer.

797210:HALXA RS01765
gene id: 797210:HALXA_RS01765
uniprot id: F8D976
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

797210:HALXA RS12895
gene id: 797210:HALXA_RS12895
uniprot id: F8D839
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

797210:HALXA RS14465
gene id: 797210:HALXA_RS14465
uniprot id: F8DAZ6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

797210:HALXA RS15510
gene id: 797210:HALXA_RS15510
uniprot id: F8DCY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

797210:HALXA RS09795
gene id: 797210:HALXA_RS09795
uniprot id: F8D313
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS04750
gene id: 797210:HALXA_RS04750
uniprot id: F8D7J0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS15925
gene id: 797210:HALXA_RS15925
uniprot id: F8D3A2
names: Similarity
messages: Belongs to the eIF-2-alpha family.

797210:HALXA RS17125
gene id: 797210:HALXA_RS17125
uniprot id: F8D511
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS05160
gene id: 797210:HALXA_RS05160
uniprot id: F8D4N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797210:HALXA RS01605
gene id: 797210:HALXA_RS01605
uniprot id: F8D950
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

797210:HALXA RS06145
gene id: 797210:HALXA_RS06145
uniprot id: F8D6G8
names: Similarity
messages: Belongs to the PspA/IM30 family.

797210:HALXA RS15970
gene id: 797210:HALXA_RS15970
uniprot id: F8D3A8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS05950
gene id: 797210:HALXA_RS05950
uniprot id: F8D7L8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

797210:HALXA RS18320
gene id: 797210:HALXA_RS18320
uniprot id: F8DE01
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS08375
gene id: 797210:HALXA_RS08375
uniprot id: F8DAS0
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

797210:HALXA RS17965
gene id: 797210:HALXA_RS17965
uniprot id: F8DD60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797210:HALXA RS18055
gene id: 797210:HALXA_RS18055
uniprot id: F8DD78
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

797210:HALXA RS09370
gene id: 797210:HALXA_RS09370
uniprot id: F8DCN7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

797210:HALXA RS15010
gene id: 797210:HALXA_RS15010
uniprot id: F8DC92
names: Similarity
messages: Belongs to the AOR/FOR family.

797210:HALXA RS04510
gene id: 797210:HALXA_RS04510
uniprot id: F8D3Y6
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS19925
gene id: 797210:HALXA_RS19925
uniprot id: F8DE71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS14745
gene id: 797210:HALXA_RS14745
uniprot id: F8DBM7
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS16125
gene id: 797210:HALXA_RS16125
uniprot id: F8D3S0
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS19130
gene id: 797210:HALXA_RS19130
uniprot id: F8DDS9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

797210:HALXA RS18755
gene id: 797210:HALXA_RS18755
uniprot id: F8DDL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS12730
gene id: 797210:HALXA_RS12730
uniprot id: F8D806
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

797210:HALXA RS20375
gene id: 797210:HALXA_RS20375
uniprot id: F8DEE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797210:HALXA RS05835
gene id: 797210:HALXA_RS05835
uniprot id: F8D7L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

797210:HALXA RS08455
gene id: 797210:HALXA_RS08455
uniprot id: F8DAT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

797210:HALXA RS10235
gene id: 797210:HALXA_RS10235
uniprot id: F8D3M2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

797210:HALXA RS00650
gene id: 797210:HALXA_RS00650
uniprot id: F8D661
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

797210:HALXA RS08780
gene id: 797210:HALXA_RS08780
uniprot id: F8DBH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

797210:HALXA RS00565
gene id: 797210:HALXA_RS00565
uniprot id: F8D709
names: Similarity
messages: Belongs to the peptidase S8 family.

797210:HALXA RS15760
gene id: 797210:HALXA_RS15760
uniprot id: F8D369
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

797210:HALXA RS01780
gene id: 797210:HALXA_RS01780
uniprot id: F8D6T2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797210:HALXA RS07850
gene id: 797210:HALXA_RS07850
uniprot id: F8D9F7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS00575
gene id: 797210:HALXA_RS00575
uniprot id: F8D711
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

797210:HALXA RS15465
gene id: 797210:HALXA_RS15465
uniprot id: F8DCX3
names: Similarity
messages: Belongs to the complex I subunit 3 family.

797210:HALXA RS15540
gene id: 797210:HALXA_RS15540
uniprot id: F8DCY9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

797210:HALXA RS10510
gene id: 797210:HALXA_RS10510
uniprot id: F8D3R5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

797210:HALXA RS08275
gene id: 797210:HALXA_RS08275
uniprot id: F8DAQ1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS15935
gene id: 797210:HALXA_RS15935
uniprot id: F8D3A4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

797210:HALXA RS10835
gene id: 797210:HALXA_RS10835
uniprot id: F8D4A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

797210:HALXA RS02610
gene id: 797210:HALXA_RS02610
uniprot id: F8DB76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

797210:HALXA RS01220
gene id: 797210:HALXA_RS01220
uniprot id: F8D8F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

797210:HALXA RS10035
gene id: 797210:HALXA_RS10035
uniprot id: F8D355
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.

797210:HALXA RS03645
gene id: 797210:HALXA_RS03645
uniprot id: F8DCL8
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

797210:HALXA RS17010
gene id: 797210:HALXA_RS17010
uniprot id: F8D4Z1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS02685
gene id: 797210:HALXA_RS02685
uniprot id: F8DB90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797210:HALXA RS16545
gene id: 797210:HALXA_RS16545
uniprot id: F8D4B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS17025
gene id: 797210:HALXA_RS17025
uniprot id: F8D4Z4
names: Function
messages: Part of a potassium transport system.

797210:HALXA RS15390
gene id: 797210:HALXA_RS15390
uniprot id: F8DCV9
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS00930
gene id: 797210:HALXA_RS00930
uniprot id: F8D666
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

797210:HALXA RS14380
gene id: 797210:HALXA_RS14380
uniprot id: F8DAX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

797210:HALXA RS12525
gene id: 797210:HALXA_RS12525
uniprot id: F8DAC0
names: Similarity
messages: Belongs to the CutA family.

797210:HALXA RS04610
gene id: 797210:HALXA_RS04610
uniprot id: F8D405
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS05230
gene id: 797210:HALXA_RS05230
uniprot id: F8D7K1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797210:HALXA RS08765
gene id: 797210:HALXA_RS08765
uniprot id: F8DBH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

797210:HALXA RS16035
gene id: 797210:HALXA_RS16035
uniprot id: F8D3B8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

797210:HALXA RS16805
gene id: 797210:HALXA_RS16805
uniprot id: F8D4G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

797210:HALXA RS14945
gene id: 797210:HALXA_RS14945
uniprot id: F8DBR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

797210:HALXA RS10660
gene id: 797210:HALXA_RS10660
uniprot id: F8D471
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS16235
gene id: 797210:HALXA_RS16235
uniprot id: F8D3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS06890
gene id: 797210:HALXA_RS06890
uniprot id: F8D7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

797210:HALXA RS09590
gene id: 797210:HALXA_RS09590
uniprot id: F8DCT0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797210:HALXA RS19440
gene id: 797210:HALXA_RS19440
uniprot id: F8DE17
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

797210:HALXA RS05190
gene id: 797210:HALXA_RS05190
uniprot id: F8D4N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

797210:HALXA RS20265
gene id: 797210:HALXA_RS20265
uniprot id: F8DED0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS03380
gene id: 797210:HALXA_RS03380
uniprot id: F8DCG6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS00140
gene id: 797210:HALXA_RS00140
uniprot id: F8D6A5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

797210:HALXA RS11995
gene id: 797210:HALXA_RS11995
uniprot id: F8D6K8
names: Similarity
messages: Belongs to the SDO1/SBDS family.

797210:HALXA RS04730
gene id: 797210:HALXA_RS04730
uniprot id: F8D426
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

797210:HALXA RS12385
gene id: 797210:HALXA_RS12385
uniprot id: F8D7A9
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS08560
gene id: 797210:HALXA_RS08560
uniprot id: F8DAV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

797210:HALXA RS03320
gene id: 797210:HALXA_RS03320
uniprot id: F8DC15
names: Similarity
messages: Belongs to the threonine aldolase family.

797210:HALXA RS17775
gene id: 797210:HALXA_RS17775
uniprot id: F8D646
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

797210:HALXA RS18085
gene id: 797210:HALXA_RS18085
uniprot id: F8DD84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS01135
gene id: 797210:HALXA_RS01135
uniprot id: F8D8D3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

797210:HALXA RS13135
gene id: 797210:HALXA_RS13135
uniprot id: F8D8R8
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

797210:HALXA RS00435
gene id: 797210:HALXA_RS00435
uniprot id: F8D6Y0
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

797210:HALXA RS07070
gene id: 797210:HALXA_RS07070
uniprot id: F8D898
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

797210:HALXA RS04655
gene id: 797210:HALXA_RS04655
uniprot id: F8D414
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

797210:HALXA RS08935
gene id: 797210:HALXA_RS08935
uniprot id: F8DBJ9
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

797210:HALXA RS16310
gene id: 797210:HALXA_RS16310
uniprot id: F8D3V6
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797210:HALXA RS06395
gene id: 797210:HALXA_RS06395
uniprot id: F8D740
names: Similarity
messages: Belongs to the RutC family.

797210:HALXA RS08450
gene id: 797210:HALXA_RS08450
uniprot id: F8DAT4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

797210:HALXA RS00215
gene id: 797210:HALXA_RS00215
uniprot id: F8D6B9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

797210:HALXA RS16685
gene id: 797210:HALXA_RS16685
uniprot id: F8D4E5
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

797210:HALXA RS04080
gene id: 797210:HALXA_RS04080
uniprot id: F8D301
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

797210:HALXA RS00520
gene id: 797210:HALXA_RS00520
uniprot id: F8D6Z9
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

797210:HALXA RS16535
gene id: 797210:HALXA_RS16535
uniprot id: F8D4B7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS06630
gene id: 797210:HALXA_RS06630
uniprot id: F8D782
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

797210:HALXA RS16695
gene id: 797210:HALXA_RS16695
uniprot id: F8D4E7
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS17460
gene id: 797210:HALXA_RS17460
uniprot id: F8D5K6
names: Similarity
messages: Belongs to the TPP enzyme family.

797210:HALXA RS04770
gene id: 797210:HALXA_RS04770
uniprot id: F8D428
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

797210:HALXA RS03395
gene id: 797210:HALXA_RS03395
uniprot id: F8DCG9
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

797210:HALXA RS15900
gene id: 797210:HALXA_RS15900
uniprot id: F8D397
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

797210:HALXA RS01150
gene id: 797210:HALXA_RS01150
uniprot id: F8D8D6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS11465
gene id: 797210:HALXA_RS11465
uniprot id: F8D5D5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS02965
gene id: 797210:HALXA_RS02965
uniprot id: F8DBD7
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS11710
gene id: 797210:HALXA_RS11710
uniprot id: F8D5W2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

797210:HALXA RS06530
gene id: 797210:HALXA_RS06530
uniprot id: F8D764
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

797210:HALXA RS06545
gene id: 797210:HALXA_RS06545
uniprot id: F8D767
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

797210:HALXA RS02045
gene id: 797210:HALXA_RS02045
uniprot id: F8D9W4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

797210:HALXA RS02700
gene id: 797210:HALXA_RS02700
uniprot id: F8DB93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

797210:HALXA RS01580
gene id: 797210:HALXA_RS01580
uniprot id: F8D945
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

797210:HALXA RS15545
gene id: 797210:HALXA_RS15545
uniprot id: F8DCZ0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

797210:HALXA RS04475
gene id: 797210:HALXA_RS04475
uniprot id: F8D3J8
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS18865
gene id: 797210:HALXA_RS18865
uniprot id: F8DDN1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS09545
gene id: 797210:HALXA_RS09545
uniprot id: F8DCS2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS01825
gene id: 797210:HALXA_RS01825
uniprot id: F8D986
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS04445
gene id: 797210:HALXA_RS04445
uniprot id: F8D3J3
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS10395
gene id: 797210:HALXA_RS10395
uniprot id: F8D3P8
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

797210:HALXA RS09470
gene id: 797210:HALXA_RS09470
uniprot id: F8DCQ7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

797210:HALXA RS02345
gene id: 797210:HALXA_RS02345
uniprot id: F8DAJ4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

797210:HALXA RS19225
gene id: 797210:HALXA_RS19225
uniprot id: F8DDU7
names: Similarity
messages: Belongs to the pirin family.

797210:HALXA RS07640
gene id: 797210:HALXA_RS07640
uniprot id: F8D9C1
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

797210:HALXA RS20275
gene id: 797210:HALXA_RS20275
uniprot id: F8DED1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

797210:HALXA RS04055
gene id: 797210:HALXA_RS04055
uniprot id: F8D2Z8
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.

797210:HALXA RS09365
gene id: 797210:HALXA_RS09365
uniprot id: F8DC90
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797210:HALXA RS03415
gene id: 797210:HALXA_RS03415
uniprot id: F8DCH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

797210:HALXA RS07800
gene id: 797210:HALXA_RS07800
uniprot id: F8D9E8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

797210:HALXA RS07010
gene id: 797210:HALXA_RS07010
uniprot id: F8D7Z1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS08925
gene id: 797210:HALXA_RS08925
uniprot id: F8DBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

797210:HALXA RS00790
gene id: 797210:HALXA_RS00790
uniprot id: F8D7N7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS19860
gene id: 797210:HALXA_RS19860
uniprot id: F8DE60
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS10135
gene id: 797210:HALXA_RS10135
uniprot id: F8D3K2
names: Similarity
messages: Belongs to the acylphosphatase family.

797210:HALXA RS17735
gene id: 797210:HALXA_RS17735
uniprot id: F8D641
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

797210:HALXA RS00940
gene id: 797210:HALXA_RS00940
uniprot id: F8D7R8
names: Subcellular Location Annotation
messages: Cell membrane

797210:HALXA RS08715
gene id: 797210:HALXA_RS08715
uniprot id: F8DBG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Nucleus

797210:HALXA RS12605
gene id: 797210:HALXA_RS12605
uniprot id: F8D7F2
names: Similarity
messages: Belongs to the peptidase C56 family.

797210:HALXA RS05025
gene id: 797210:HALXA_RS05025
uniprot id: F8D4K9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS16820
gene id: 797210:HALXA_RS16820
uniprot id: F8D4G8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

797210:HALXA RS05175
gene id: 797210:HALXA_RS05175
uniprot id: F8D4N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

797210:HALXA RS03780
gene id: 797210:HALXA_RS03780
uniprot id: F8D2U7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

797210:HALXA RS01915
gene id: 797210:HALXA_RS01915
uniprot id: F8D9T8
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS17310
gene id: 797210:HALXA_RS17310
uniprot id: F8D5H5
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

797210:HALXA RS14290
gene id: 797210:HALXA_RS14290
uniprot id: F8DAW1
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

797210:HALXA RS10790
gene id: 797210:HALXA_RS10790
uniprot id: F8D493
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

797210:HALXA RS19115
gene id: 797210:HALXA_RS19115
uniprot id: F8DDS6
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS07280
gene id: 797210:HALXA_RS07280
uniprot id: F8D8N1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS05705
gene id: 797210:HALXA_RS05705
uniprot id: F8D5P6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

797210:HALXA RS10525
gene id: 797210:HALXA_RS10525
uniprot id: F8D445
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

797210:HALXA RS05170
gene id: 797210:HALXA_RS05170
uniprot id: F8D7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

797210:HALXA RS09330
gene id: 797210:HALXA_RS09330
uniprot id: F8DC83
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS10735
gene id: 797210:HALXA_RS10735
uniprot id: F8D9P1
names: Similarity
messages: Belongs to the DtxR/MntR family.

797210:HALXA RS09955
gene id: 797210:HALXA_RS09955
uniprot id: F8D908
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS08310
gene id: 797210:HALXA_RS08310
uniprot id: F8DAQ7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

797210:HALXA RS01755
gene id: 797210:HALXA_RS01755
uniprot id: F8D974
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS12420
gene id: 797210:HALXA_RS12420
uniprot id: F8D7B6
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS04440
gene id: 797210:HALXA_RS04440
uniprot id: F8D7I5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS16085
gene id: 797210:HALXA_RS16085
uniprot id: F8D3C6
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS01935
gene id: 797210:HALXA_RS01935
uniprot id: F8D9U1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS00160
gene id: 797210:HALXA_RS00160
uniprot id: F8D6A9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

797210:HALXA RS05235
gene id: 797210:HALXA_RS05235
uniprot id: F8D4P1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS02595
gene id: 797210:HALXA_RS02595
uniprot id: F8DAN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS05960
gene id: 797210:HALXA_RS05960
uniprot id: F8D5T7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

797210:HALXA RS20480
gene id: 797210:HALXA_RS20480
uniprot id: F8DEM3
names: Similarity
messages: Belongs to the MCM family.

797210:HALXA RS08630
gene id: 797210:HALXA_RS08630
uniprot id: F8DBE7
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS00270
gene id: 797210:HALXA_RS00270
uniprot id: F8D6C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

797210:HALXA RS08855
gene id: 797210:HALXA_RS08855
uniprot id: F8DBI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

797210:HALXA RS01620
gene id: 797210:HALXA_RS01620
uniprot id: F8D953
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

797210:HALXA RS03400
gene id: 797210:HALXA_RS03400
uniprot id: F8DCH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS19360
gene id: 797210:HALXA_RS19360
uniprot id: F8DDX3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

797210:HALXA RS04155
gene id: 797210:HALXA_RS04155
uniprot id: F8D3E2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

797210:HALXA RS01610
gene id: 797210:HALXA_RS01610
uniprot id: F8D951
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

797210:HALXA RS02235
gene id: 797210:HALXA_RS02235
uniprot id: F8DAH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homodimer.

797210:HALXA RS04690
gene id: 797210:HALXA_RS04690
uniprot id: F8D420
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

797210:HALXA RS09190
gene id: 797210:HALXA_RS09190
uniprot id: F8DC63
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

797210:HALXA RS03965
gene id: 797210:HALXA_RS03965
uniprot id: F8D7H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS05590
gene id: 797210:HALXA_RS05590
uniprot id: F8D7L0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

797210:HALXA RS05965
gene id: 797210:HALXA_RS05965
uniprot id: F8D5T8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

797210:HALXA RS17670
gene id: 797210:HALXA_RS17670
uniprot id: F8D629
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS14495
gene id: 797210:HALXA_RS14495
uniprot id: F8DB00
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

797210:HALXA RS02480
gene id: 797210:HALXA_RS02480
uniprot id: F8DAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS09305
gene id: 797210:HALXA_RS09305
uniprot id: F8DC79
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS11290
gene id: 797210:HALXA_RS11290
uniprot id: F8D5A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

797210:HALXA RS17370
gene id: 797210:HALXA_RS17370
uniprot id: F8D5I8
names: Similarity
messages: Belongs to the AOR/FOR family.

797210:HALXA RS13760
gene id: 797210:HALXA_RS13760
uniprot id: F8D9K9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

797210:HALXA RS13825
gene id: 797210:HALXA_RS13825
uniprot id: F8DAF4
names: Similarity
messages: Belongs to the AAA ATPase family.

797210:HALXA RS05310
gene id: 797210:HALXA_RS05310
uniprot id: F8D539
names: Similarity
messages: Belongs to the cytochrome P450 family.

797210:HALXA RS03930
gene id: 797210:HALXA_RS03930
uniprot id: F8D6W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

797210:HALXA RS02755
gene id: 797210:HALXA_RS02755
uniprot id: F8DBA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

797210:HALXA RS18255
gene id: 797210:HALXA_RS18255
uniprot id: F8DDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS16010
gene id: 797210:HALXA_RS16010
uniprot id: F8DB62
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

797210:HALXA RS00325
gene id: 797210:HALXA_RS00325
uniprot id: F8D6D4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS09985
gene id: 797210:HALXA_RS09985
uniprot id: F8D348
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS13670
gene id: 797210:HALXA_RS13670
uniprot id: F8D9J2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

797210:HALXA RS07420
gene id: 797210:HALXA_RS07420
uniprot id: F8D8Q1
names: Similarity
messages: Belongs to the threonine synthase family.

797210:HALXA RS06025
gene id: 797210:HALXA_RS06025
uniprot id: F8D6E3
names: Function
messages: Part of a potassium transport system.

797210:HALXA RS19425
gene id: 797210:HALXA_RS19425
uniprot id: F8DDY4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS01960
gene id: 797210:HALXA_RS01960
uniprot id: F8D9U6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

797210:HALXA RS01905
gene id: 797210:HALXA_RS01905
uniprot id: F8D9T6
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS13505
gene id: 797210:HALXA_RS13505
uniprot id: F8D8X3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797210:HALXA RS01120
gene id: 797210:HALXA_RS01120
uniprot id: F8D8D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS01715
gene id: 797210:HALXA_RS01715
uniprot id: F8D967
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

797210:HALXA RS19290
gene id: 797210:HALXA_RS19290
uniprot id: F8DDV9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

797210:HALXA RS10165
gene id: 797210:HALXA_RS10165
uniprot id: F8D3K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.

797210:HALXA RS04480
gene id: 797210:HALXA_RS04480
uniprot id: F8D3Y0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

797210:HALXA RS05510
gene id: 797210:HALXA_RS05510
uniprot id: F8D572
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS14630
gene id: 797210:HALXA_RS14630
uniprot id: F8DB19
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

797210:HALXA RS04665
gene id: 797210:HALXA_RS04665
uniprot id: F8D416
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

797210:HALXA RS18260
gene id: 797210:HALXA_RS18260
uniprot id: F8DDB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS01745
gene id: 797210:HALXA_RS01745
uniprot id: F8D973
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS16285
gene id: 797210:HALXA_RS16285
uniprot id: F8D3V2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797210:HALXA RS05050
gene id: 797210:HALXA_RS05050
uniprot id: F8D4L4
names: Similarity
messages: Belongs to the AOR/FOR family.

797210:HALXA RS12965
gene id: 797210:HALXA_RS12965
uniprot id: F8D851
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS04900
gene id: 797210:HALXA_RS04900
uniprot id: F8D4I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

797210:HALXA RS08540
gene id: 797210:HALXA_RS08540
uniprot id: F8DAU9
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS00300
gene id: 797210:HALXA_RS00300
uniprot id: F8D6D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

797210:HALXA RS02580
gene id: 797210:HALXA_RS02580
uniprot id: F8D6U9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797210:HALXA RS14370
gene id: 797210:HALXA_RS14370
uniprot id: F8DAX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

797210:HALXA RS00150
gene id: 797210:HALXA_RS00150
uniprot id: F8D6A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

797210:HALXA RS02435
gene id: 797210:HALXA_RS02435
uniprot id: F8DAL2
names: Similarity
messages: Belongs to the peptidase S9C family.

797210:HALXA RS05125
gene id: 797210:HALXA_RS05125
uniprot id: F8D7J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS19790
gene id: 797210:HALXA_RS19790
uniprot id: F8DE46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS14925
gene id: 797210:HALXA_RS14925
uniprot id: F8DBR0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

797210:HALXA RS00080
gene id: 797210:HALXA_RS00080
uniprot id: F8D693
names: Similarity
messages: Belongs to the PEPCase type 1 family.

797210:HALXA RS02335
gene id: 797210:HALXA_RS02335
uniprot id: F8DAJ2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797210:HALXA RS02765
gene id: 797210:HALXA_RS02765
uniprot id: F8DBA6
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

797210:HALXA RS12960
gene id: 797210:HALXA_RS12960
uniprot id: F8D850
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS12835
gene id: 797210:HALXA_RS12835
uniprot id: F8D827
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

797210:HALXA RS11575
gene id: 797210:HALXA_RS11575
uniprot id: F8D5F5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

797210:HALXA RS02070
gene id: 797210:HALXA_RS02070
uniprot id: F8D9W9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797210:HALXA RS16540
gene id: 797210:HALXA_RS16540
uniprot id: F8D4B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS15270
gene id: 797210:HALXA_RS15270
uniprot id: F8DCE3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS06990
gene id: 797210:HALXA_RS06990
uniprot id: F8D7Y8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

797210:HALXA RS06905
gene id: 797210:HALXA_RS06905
uniprot id: F8D7X4
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS05185
gene id: 797210:HALXA_RS05185
uniprot id: F8D4N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

797210:HALXA RS05280
gene id: 797210:HALXA_RS05280
uniprot id: F8D533
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

797210:HALXA RS00165
gene id: 797210:HALXA_RS00165
uniprot id: F8D6B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

797210:HALXA RS09495
gene id: 797210:HALXA_RS09495
uniprot id: F8DCR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS03840
gene id: 797210:HALXA_RS03840
uniprot id: F8D2V9
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

797210:HALXA RS15965
gene id: 797210:HALXA_RS15965
uniprot id: F8DB60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS10095
gene id: 797210:HALXA_RS10095
uniprot id: F8D365
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797210:HALXA RS15135
gene id: 797210:HALXA_RS15135
uniprot id: F8DCB7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS02560
gene id: 797210:HALXA_RS02560
uniprot id: F8DAN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS00675
gene id: 797210:HALXA_RS00675
uniprot id: F8D727
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gas vesicle GvpA family.
messages: Gas vesicle shell
messages: Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.
messages: The gas vesicle shell is 2 nm thick and consists of a single layer of this protein. It forms helical ribs nearly perpendicular to the long axis of the vesicle.

797210:HALXA RS18360
gene id: 797210:HALXA_RS18360
uniprot id: F8DE02
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS04530
gene id: 797210:HALXA_RS04530
uniprot id: F8D3Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

797210:HALXA RS00235
gene id: 797210:HALXA_RS00235
uniprot id: F8D650
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS16795
gene id: 797210:HALXA_RS16795
uniprot id: F8D4G5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797210:HALXA RS10000
gene id: 797210:HALXA_RS10000
uniprot id: F8D350
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

797210:HALXA RS15210
gene id: 797210:HALXA_RS15210
uniprot id: F8DCD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS16405
gene id: 797210:HALXA_RS16405
uniprot id: F8D3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

797210:HALXA RS02120
gene id: 797210:HALXA_RS02120
uniprot id: F8D6T7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

797210:HALXA RS07900
gene id: 797210:HALXA_RS07900
uniprot id: F8D9Z3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS01640
gene id: 797210:HALXA_RS01640
uniprot id: F8D957
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

797210:HALXA RS03210
gene id: 797210:HALXA_RS03210
uniprot id: F8DBZ7
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS10020
gene id: 797210:HALXA_RS10020
uniprot id: F8D353
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

797210:HALXA RS10320
gene id: 797210:HALXA_RS10320
uniprot id: F8D919
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

797210:HALXA RS13165
gene id: 797210:HALXA_RS13165
uniprot id: F8D8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS18580
gene id: 797210:HALXA_RS18580
uniprot id: F8DDI0
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS12595
gene id: 797210:HALXA_RS12595
uniprot id: F8D7F0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

797210:HALXA RS10110
gene id: 797210:HALXA_RS10110
uniprot id: F8D367
names: Similarity
messages: Belongs to the UPF0212 family.

797210:HALXA RS05320
gene id: 797210:HALXA_RS05320
uniprot id: F8D541
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

797210:HALXA RS12570
gene id: 797210:HALXA_RS12570
uniprot id: F8D7E5
names: Similarity
messages: Belongs to the BtpA family.

797210:HALXA RS01575
gene id: 797210:HALXA_RS01575
uniprot id: F8D944
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

797210:HALXA RS17650
gene id: 797210:HALXA_RS17650
uniprot id: F8D624
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

797210:HALXA RS04575
gene id: 797210:HALXA_RS04575
uniprot id: F8D3Z8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS03705
gene id: 797210:HALXA_RS03705
uniprot id: F8DCN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

797210:HALXA RS15730
gene id: 797210:HALXA_RS15730
uniprot id: F8DB58
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS06960
gene id: 797210:HALXA_RS06960
uniprot id: F8D891
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

797210:HALXA RS04050
gene id: 797210:HALXA_RS04050
uniprot id: F8D2Z7
names: Similarity
messages: Belongs to the HMBS family.

797210:HALXA RS11585
gene id: 797210:HALXA_RS11585
uniprot id: F8D5F7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

797210:HALXA RS12950
gene id: 797210:HALXA_RS12950
uniprot id: F8D848
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

797210:HALXA RS02535
gene id: 797210:HALXA_RS02535
uniprot id: F8DAM9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

797210:HALXA RS04070
gene id: 797210:HALXA_RS04070
uniprot id: F8D300
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

797210:HALXA RS17790
gene id: 797210:HALXA_RS17790
uniprot id: F8DBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

797210:HALXA RS04685
gene id: 797210:HALXA_RS04685
uniprot id: F8D7I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

797210:HALXA RS16000
gene id: 797210:HALXA_RS16000
uniprot id: F8D3B3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS14940
gene id: 797210:HALXA_RS14940
uniprot id: F8DB39
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

797210:HALXA RS04310
gene id: 797210:HALXA_RS04310
uniprot id: F8D3H3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797210:HALXA RS08555
gene id: 797210:HALXA_RS08555
uniprot id: F8DAV2
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

797210:HALXA RS08995
gene id: 797210:HALXA_RS08995
uniprot id: F8DC22
names: Subunit
messages: Homotrimer.

797210:HALXA RS18005
gene id: 797210:HALXA_RS18005
uniprot id: F8DD70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS02240
gene id: 797210:HALXA_RS02240
uniprot id: F8DAH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS15735
gene id: 797210:HALXA_RS15735
uniprot id: F8DD21
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

797210:HALXA RS19785
gene id: 797210:HALXA_RS19785
uniprot id: F8DE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

797210:HALXA RS05420
gene id: 797210:HALXA_RS05420
uniprot id: F8D562
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

797210:HALXA RS13695
gene id: 797210:HALXA_RS13695
uniprot id: F8D9J8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS10775
gene id: 797210:HALXA_RS10775
uniprot id: F8D490
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. RAD50 subfamily.
messages: Binds 1 zinc ion per homodimer.
messages: Homodimer. Forms a heterotetramer composed of two Mre11 subunits and two Rad50 subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
messages: The two conserved Cys that bind zinc constitute the zinc-hook, which separates the large intramolecular coiled coil regions. The 2 Cys residues coordinate one molecule of zinc with the help of the 2 Cys residues of the zinc-hook of another Rad50 molecule, thereby forming a V-shaped homodimer.

797210:HALXA RS17075
gene id: 797210:HALXA_RS17075
uniprot id: F8D504
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS02995
gene id: 797210:HALXA_RS02995
uniprot id: F8DBV1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

797210:HALXA RS07190
gene id: 797210:HALXA_RS07190
uniprot id: F8D8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

797210:HALXA RS03820
gene id: 797210:HALXA_RS03820
uniprot id: F8D2V5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797210:HALXA RS17755
gene id: 797210:HALXA_RS17755
uniprot id: F8DBU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

797210:HALXA RS01945
gene id: 797210:HALXA_RS01945
uniprot id: F8D9U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

797210:HALXA RS03460
gene id: 797210:HALXA_RS03460
uniprot id: F8DCI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

797210:HALXA RS02725
gene id: 797210:HALXA_RS02725
uniprot id: F8DB98
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

797210:HALXA RS02025
gene id: 797210:HALXA_RS02025
uniprot id: F8D9W0
names: Similarity
messages: Belongs to the Nth/MutY family.

797210:HALXA RS14185
gene id: 797210:HALXA_RS14185
uniprot id: F8DAA2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

797210:HALXA RS13035
gene id: 797210:HALXA_RS13035
uniprot id: F8DAD3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: S-layer

797210:HALXA RS14650
gene id: 797210:HALXA_RS14650
uniprot id: F8DB34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

797210:HALXA RS13675
gene id: 797210:HALXA_RS13675
uniprot id: F8D9J3
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS13855
gene id: 797210:HALXA_RS13855
uniprot id: F8DAF6
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797210:HALXA RS15275
gene id: 797210:HALXA_RS15275
uniprot id: F8DCE4
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS02380
gene id: 797210:HALXA_RS02380
uniprot id: F8DAK1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

797210:HALXA RS15820
gene id: 797210:HALXA_RS15820
uniprot id: F8D381
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

797210:HALXA RS12265
gene id: 797210:HALXA_RS12265
uniprot id: F8D6Q7
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

797210:HALXA RS06965
gene id: 797210:HALXA_RS06965
uniprot id: F8D7Y4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Part of the 30S ribosomal subunit.

797210:HALXA RS07955
gene id: 797210:HALXA_RS07955
uniprot id: F8DA04
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

797210:HALXA RS13530
gene id: 797210:HALXA_RS13530
uniprot id: F8D9G5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS16470
gene id: 797210:HALXA_RS16470
uniprot id: F8DBS6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

797210:HALXA RS08130
gene id: 797210:HALXA_RS08130
uniprot id: F8D8C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

797210:HALXA RS00705
gene id: 797210:HALXA_RS00705
uniprot id: F8D732
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpK family.
messages: Gas vesicle
messages: Vesicle

797210:HALXA RS19175
gene id: 797210:HALXA_RS19175
uniprot id: F8DDT7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797210:HALXA RS02115
gene id: 797210:HALXA_RS02115
uniprot id: F8D9X4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: The active site is a redox-active disulfide bond.

797210:HALXA RS00905
gene id: 797210:HALXA_RS00905
uniprot id: F8D7R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

797210:HALXA RS10585
gene id: 797210:HALXA_RS10585
uniprot id: F8D457
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

797210:HALXA RS13870
gene id: 797210:HALXA_RS13870
uniprot id: F8D9M5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS04455
gene id: 797210:HALXA_RS04455
uniprot id: F8D3J4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS09615
gene id: 797210:HALXA_RS09615
uniprot id: F8DCT5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

797210:HALXA RS12290
gene id: 797210:HALXA_RS12290
uniprot id: F8D6R0
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

797210:HALXA RS19195
gene id: 797210:HALXA_RS19195
uniprot id: F8DDU1
names: Similarity
messages: Belongs to the RutC family.

797210:HALXA RS19970
gene id: 797210:HALXA_RS19970
uniprot id: F8DE78
names: Similarity
messages: Belongs to the NAPRTase family.

797210:HALXA RS05825
gene id: 797210:HALXA_RS05825
uniprot id: F8D5R9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

797210:HALXA RS11745
gene id: 797210:HALXA_RS11745
uniprot id: F8D5W9
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

797210:HALXA RS10505
gene id: 797210:HALXA_RS10505
uniprot id: F8D3R4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

797210:HALXA RS03540
gene id: 797210:HALXA_RS03540
uniprot id: F8DCJ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS01085
gene id: 797210:HALXA_RS01085
uniprot id: F8D7U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

797210:HALXA RS03745
gene id: 797210:HALXA_RS03745
uniprot id: F8D2U0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797210:HALXA RS18620
gene id: 797210:HALXA_RS18620
uniprot id: F8DDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS16870
gene id: 797210:HALXA_RS16870
uniprot id: F8DBT5
names: Caution
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS07520
gene id: 797210:HALXA_RS07520
uniprot id: F8D995
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS03980
gene id: 797210:HALXA_RS03980
uniprot id: F8D2Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

797210:HALXA RS01585
gene id: 797210:HALXA_RS01585
uniprot id: F8D946
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

797210:HALXA RS08645
gene id: 797210:HALXA_RS08645
uniprot id: F8DBF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

797210:HALXA RS07475
gene id: 797210:HALXA_RS07475
uniprot id: F8D8R1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS12105
gene id: 797210:HALXA_RS12105
uniprot id: F8D6N0
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

797210:HALXA RS14935
gene id: 797210:HALXA_RS14935
uniprot id: F8DBR2
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS12720
gene id: 797210:HALXA_RS12720
uniprot id: F8D7G9
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797210:HALXA RS09140
gene id: 797210:HALXA_RS09140
uniprot id: F8DC53
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

797210:HALXA RS11795
gene id: 797210:HALXA_RS11795
uniprot id: F8D5Y0
names: Similarity
messages: Belongs to the peptidase M24B family.

797210:HALXA RS15695
gene id: 797210:HALXA_RS15695
uniprot id: F8DD15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS13055
gene id: 797210:HALXA_RS13055
uniprot id: F8D865
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

797210:HALXA RS09060
gene id: 797210:HALXA_RS09060
uniprot id: F8DC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

797210:HALXA RS01005
gene id: 797210:HALXA_RS01005
uniprot id: F8D7S7
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

797210:HALXA RS08390
gene id: 797210:HALXA_RS08390
uniprot id: F8DAS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

797210:HALXA RS03785
gene id: 797210:HALXA_RS03785
uniprot id: F8D2U8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

797210:HALXA RS12190
gene id: 797210:HALXA_RS12190
uniprot id: F8D9S3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

797210:HALXA RS13085
gene id: 797210:HALXA_RS13085
uniprot id: F8D869
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

797210:HALXA RS05665
gene id: 797210:HALXA_RS05665
uniprot id: F8D5N8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

797210:HALXA RS06875
gene id: 797210:HALXA_RS06875
uniprot id: F8D7W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

797210:HALXA RS01155
gene id: 797210:HALXA_RS01155
uniprot id: F8D8D7
names: Similarity
messages: Belongs to the arginase family.

797210:HALXA RS00175
gene id: 797210:HALXA_RS00175
uniprot id: F8D6B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

797210:HALXA RS20035
gene id: 797210:HALXA_RS20035
uniprot id: F8DE87
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

797210:HALXA RS00170
gene id: 797210:HALXA_RS00170
uniprot id: F8D6B1
names: Similarity
messages: Belongs to the UPF0145 family.

797210:HALXA RS13245
gene id: 797210:HALXA_RS13245
uniprot id: F8D8U0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

797210:HALXA RS08380
gene id: 797210:HALXA_RS08380
uniprot id: F8DAS1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS01940
gene id: 797210:HALXA_RS01940
uniprot id: F8D9U2
names: Similarity
messages: Belongs to the TrpF family.

797210:HALXA RS08170
gene id: 797210:HALXA_RS08170
uniprot id: F8DA46
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS06730
gene id: 797210:HALXA_RS06730
uniprot id: F8D886
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS14270
gene id: 797210:HALXA_RS14270
uniprot id: F8DAB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

797210:HALXA RS18825
gene id: 797210:HALXA_RS18825
uniprot id: F8DDM2
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS17305
gene id: 797210:HALXA_RS17305
uniprot id: F8D5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

797210:HALXA RS02855
gene id: 797210:HALXA_RS02855
uniprot id: F8DBC0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

797210:HALXA RS06600
gene id: 797210:HALXA_RS06600
uniprot id: F8D776
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

797210:HALXA RS12970
gene id: 797210:HALXA_RS12970
uniprot id: F8D852
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS10375
gene id: 797210:HALXA_RS10375
uniprot id: F8D3P5
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

797210:HALXA RS17330
gene id: 797210:HALXA_RS17330
uniprot id: F8D5H9
names: Similarity
messages: Belongs to the peptidase C56 family.

797210:HALXA RS12545
gene id: 797210:HALXA_RS12545
uniprot id: F8D7E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

797210:HALXA RS01595
gene id: 797210:HALXA_RS01595
uniprot id: F8D948
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

797210:HALXA RS11680
gene id: 797210:HALXA_RS11680
uniprot id: F8D5V5
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797210:HALXA RS02645
gene id: 797210:HALXA_RS02645
uniprot id: F8DB82
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS07670
gene id: 797210:HALXA_RS07670
uniprot id: F8D8B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

797210:HALXA RS04525
gene id: 797210:HALXA_RS04525
uniprot id: F8D3Y9
names: Similarity
messages: Belongs to the TFIIB family.

797210:HALXA RS00680
gene id: 797210:HALXA_RS00680
uniprot id: F8D728
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle GvpF/GvpL family.
messages: Gas vesicle
messages: Vesicle

797210:HALXA RS11960
gene id: 797210:HALXA_RS11960
uniprot id: F8D9S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS02390
gene id: 797210:HALXA_RS02390
uniprot id: F8DAK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

797210:HALXA RS17195
gene id: 797210:HALXA_RS17195
uniprot id: F8DBU0
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS15090
gene id: 797210:HALXA_RS15090
uniprot id: F8DCA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

797210:HALXA RS14660
gene id: 797210:HALXA_RS14660
uniprot id: F8DBK9
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

797210:HALXA RS16615
gene id: 797210:HALXA_RS16615
uniprot id: F8D4D3
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

797210:HALXA RS15030
gene id: 797210:HALXA_RS15030
uniprot id: F8DC96
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS04495
gene id: 797210:HALXA_RS04495
uniprot id: F8D3Y3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

797210:HALXA RS10390
gene id: 797210:HALXA_RS10390
uniprot id: F8D3P7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

797210:HALXA RS16680
gene id: 797210:HALXA_RS16680
uniprot id: F8D4E4
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS05905
gene id: 797210:HALXA_RS05905
uniprot id: F8D5T0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797210:HALXA RS05580
gene id: 797210:HALXA_RS05580
uniprot id: F8D585
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

797210:HALXA RS03690
gene id: 797210:HALXA_RS03690
uniprot id: F8DCM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS02295
gene id: 797210:HALXA_RS02295
uniprot id: F8DAI3
names: Function
messages: Protects DNA against thermal denaturation and modulates transcription.

797210:HALXA RS06255
gene id: 797210:HALXA_RS06255
uniprot id: F8D6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS13555
gene id: 797210:HALXA_RS13555
uniprot id: F8D9H0
names: Similarity
messages: Belongs to the NAD synthetase family.

797210:HALXA RS17365
gene id: 797210:HALXA_RS17365
uniprot id: F8D5I6
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS16555
gene id: 797210:HALXA_RS16555
uniprot id: F8D4C1
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797210:HALXA RS15230
gene id: 797210:HALXA_RS15230
uniprot id: F8DB47
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS19230
gene id: 797210:HALXA_RS19230
uniprot id: F8DDU8
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS16110
gene id: 797210:HALXA_RS16110
uniprot id: F8D3R7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

797210:HALXA RS12530
gene id: 797210:HALXA_RS12530
uniprot id: F8D7D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

797210:HALXA RS17875
gene id: 797210:HALXA_RS17875
uniprot id: F8DD41
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS18645
gene id: 797210:HALXA_RS18645
uniprot id: F8DDJ3
names: Similarity
messages: Belongs to the SfsA family.

797210:HALXA RS06015
gene id: 797210:HALXA_RS06015
uniprot id: F8D6E1
names: Similarity
messages: Belongs to the thymidylate kinase family.

797210:HALXA RS17115
gene id: 797210:HALXA_RS17115
uniprot id: F8D509
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS01230
gene id: 797210:HALXA_RS01230
uniprot id: F8D8F2
names: Similarity
messages: Belongs to the peptidase S8 family.

797210:HALXA RS02985
gene id: 797210:HALXA_RS02985
uniprot id: F8DBE0
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS11510
gene id: 797210:HALXA_RS11510
uniprot id: F8D5E1
names: Similarity
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.

797210:HALXA RS06615
gene id: 797210:HALXA_RS06615
uniprot id: F8D779
names: Similarity
messages: Belongs to the UPF0215 family.

797210:HALXA RS05715
gene id: 797210:HALXA_RS05715
uniprot id: F8D5P8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

797210:HALXA RS11735
gene id: 797210:HALXA_RS11735
uniprot id: F8D5W7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

797210:HALXA RS14150
gene id: 797210:HALXA_RS14150
uniprot id: F8DA98
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797210:HALXA RS05830
gene id: 797210:HALXA_RS05830
uniprot id: F8D5S0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

797210:HALXA RS03195
gene id: 797210:HALXA_RS03195
uniprot id: F8DBZ4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

797210:HALXA RS07560
gene id: 797210:HALXA_RS07560
uniprot id: F8D9A3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

797210:HALXA RS16625
gene id: 797210:HALXA_RS16625
uniprot id: F8D4D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

797210:HALXA RS17840
gene id: 797210:HALXA_RS17840
uniprot id: F8DD34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

797210:HALXA RS04205
gene id: 797210:HALXA_RS04205
uniprot id: F8D3F2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

797210:HALXA RS15850
gene id: 797210:HALXA_RS15850
uniprot id: F8D387
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

797210:HALXA RS15930
gene id: 797210:HALXA_RS15930
uniprot id: F8D3A3
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

797210:HALXA RS05745
gene id: 797210:HALXA_RS05745
uniprot id: F8D5Q4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

797210:HALXA RS02375
gene id: 797210:HALXA_RS02375
uniprot id: F8DAK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

797210:HALXA RS12515
gene id: 797210:HALXA_RS12515
uniprot id: F8D7D6
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

797210:HALXA RS07645
gene id: 797210:HALXA_RS07645
uniprot id: F8D9C2
names: Similarity
messages: Belongs to the UPF0284 family.

797210:HALXA RS00265
gene id: 797210:HALXA_RS00265
uniprot id: F8D651
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

797210:HALXA RS03330
gene id: 797210:HALXA_RS03330
uniprot id: F8DC18
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS00635
gene id: 797210:HALXA_RS00635
uniprot id: F8D722
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

797210:HALXA RS05850
gene id: 797210:HALXA_RS05850
uniprot id: F8D7L4
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS00285
gene id: 797210:HALXA_RS00285
uniprot id: F8D653
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RNA polymerase complex.

797210:HALXA RS16710
gene id: 797210:HALXA_RS16710
uniprot id: F8D4E9
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS03475
gene id: 797210:HALXA_RS03475
uniprot id: F8DCI5
names: Similarity
messages: Belongs to the RutC family.

797210:HALXA RS13660
gene id: 797210:HALXA_RS13660
uniprot id: F8D9J0
names: Similarity
messages: Belongs to the PDCD5 family.

797210:HALXA RS03490
gene id: 797210:HALXA_RS03490
uniprot id: F8DCI8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

797210:HALXA RS02140
gene id: 797210:HALXA_RS02140
uniprot id: F8D9X7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

797210:HALXA RS18765
gene id: 797210:HALXA_RS18765
uniprot id: F8DDL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

797210:HALXA RS17255
gene id: 797210:HALXA_RS17255
uniprot id: F8D5G4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

797210:HALXA RS04215
gene id: 797210:HALXA_RS04215
uniprot id: F8D3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

797210:HALXA RS18900
gene id: 797210:HALXA_RS18900
uniprot id: F8DDN8
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS12865
gene id: 797210:HALXA_RS12865
uniprot id: F8D833
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS05760
gene id: 797210:HALXA_RS05760
uniprot id: F8D5Q7
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

797210:HALXA RS03180
gene id: 797210:HALXA_RS03180
uniprot id: F8DBZ1
names: Similarity
messages: Belongs to the UPF0201 family.

797210:HALXA RS00155
gene id: 797210:HALXA_RS00155
uniprot id: F8D6A8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

797210:HALXA RS02545
gene id: 797210:HALXA_RS02545
uniprot id: F8DAN1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797210:HALXA RS01490
gene id: 797210:HALXA_RS01490
uniprot id: F8D926
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

797210:HALXA RS06665
gene id: 797210:HALXA_RS06665
uniprot id: F8D788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

797210:HALXA RS00275
gene id: 797210:HALXA_RS00275
uniprot id: F8D652
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

797210:HALXA RS11270
gene id: 797210:HALXA_RS11270
uniprot id: F8D598
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

797210:HALXA RS04915
gene id: 797210:HALXA_RS04915
uniprot id: F8D4I6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

797210:HALXA RS04225
gene id: 797210:HALXA_RS04225
uniprot id: F8D3F6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

797210:HALXA RS18605
gene id: 797210:HALXA_RS18605
uniprot id: F8DDI5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS16785
gene id: 797210:HALXA_RS16785
uniprot id: F8D4G3
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS14420
gene id: 797210:HALXA_RS14420
uniprot id: F8DAY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

797210:HALXA RS09925
gene id: 797210:HALXA_RS09925
uniprot id: F8D907
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

797210:HALXA RS17220
gene id: 797210:HALXA_RS17220
uniprot id: F8D526
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Membrane

797210:HALXA RS07375
gene id: 797210:HALXA_RS07375
uniprot id: F8D8A7
names: Similarity
messages: Belongs to the malic enzymes family.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

797210:HALXA RS14340
gene id: 797210:HALXA_RS14340
uniprot id: F8DAX1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS20120
gene id: 797210:HALXA_RS20120
uniprot id: F8DEA2
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS18010
gene id: 797210:HALXA_RS18010
uniprot id: F8DDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS14625
gene id: 797210:HALXA_RS14625
uniprot id: F8DB18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

797210:HALXA RS03025
gene id: 797210:HALXA_RS03025
uniprot id: F8DBV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

797210:HALXA RS16360
gene id: 797210:HALXA_RS16360
uniprot id: F8D3W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

797210:HALXA RS04045
gene id: 797210:HALXA_RS04045
uniprot id: F8D2Z6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

797210:HALXA RS14620
gene id: 797210:HALXA_RS14620
uniprot id: F8DB17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

797210:HALXA RS10435
gene id: 797210:HALXA_RS10435
uniprot id: F8D9N6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS07390
gene id: 797210:HALXA_RS07390
uniprot id: F8D8P5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797210:HALXA RS14115
gene id: 797210:HALXA_RS14115
uniprot id: F8DA93
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

797210:HALXA RS01975
gene id: 797210:HALXA_RS01975
uniprot id: F8D9V0
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS03495
gene id: 797210:HALXA_RS03495
uniprot id: F8DCI9
names: Similarity
messages: Belongs to the GcvT family.

797210:HALXA RS00290
gene id: 797210:HALXA_RS00290
uniprot id: F8D6D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

797210:HALXA RS17915
gene id: 797210:HALXA_RS17915
uniprot id: F8DD50
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS10630
gene id: 797210:HALXA_RS10630
uniprot id: F8D466
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

797210:HALXA RS00600
gene id: 797210:HALXA_RS00600
uniprot id: F8D716
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS02165
gene id: 797210:HALXA_RS02165
uniprot id: F8D9Y2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797210:HALXA RS00385
gene id: 797210:HALXA_RS00385
uniprot id: F8D6X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

797210:HALXA RS18780
gene id: 797210:HALXA_RS18780
uniprot id: F8DDL5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

797210:HALXA RS05165
gene id: 797210:HALXA_RS05165
uniprot id: F8D4N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797210:HALXA RS15670
gene id: 797210:HALXA_RS15670
uniprot id: F8DD10
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

797210:HALXA RS00610
gene id: 797210:HALXA_RS00610
uniprot id: F8D660
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS08500
gene id: 797210:HALXA_RS08500
uniprot id: F8DAU1
names: Similarity
messages: Belongs to the UPF0173 family.

797210:HALXA RS05315
gene id: 797210:HALXA_RS05315
uniprot id: F8D540
names: Similarity
messages: Belongs to the thioesterase PaaI family.

797210:HALXA RS15400
gene id: 797210:HALXA_RS15400
uniprot id: F8DCW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

797210:HALXA RS19285
gene id: 797210:HALXA_RS19285
uniprot id: F8DDV8
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS11480
gene id: 797210:HALXA_RS11480
uniprot id: F8D5D8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS13780
gene id: 797210:HALXA_RS13780
uniprot id: F8D9L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

797210:HALXA RS07835
gene id: 797210:HALXA_RS07835
uniprot id: F8D9F4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797210:HALXA RS09315
gene id: 797210:HALXA_RS09315
uniprot id: F8DC81
names: Similarity
messages: Belongs to the manganese catalase family.

797210:HALXA RS10705
gene id: 797210:HALXA_RS10705
uniprot id: F8D479
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS16290
gene id: 797210:HALXA_RS16290
uniprot id: F8D3V3
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

797210:HALXA RS03845
gene id: 797210:HALXA_RS03845
uniprot id: F8D2W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

797210:HALXA RS17185
gene id: 797210:HALXA_RS17185
uniprot id: F8D521
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS05015
gene id: 797210:HALXA_RS05015
uniprot id: F8D4K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

797210:HALXA RS16355
gene id: 797210:HALXA_RS16355
uniprot id: F8DB72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

797210:HALXA RS18210
gene id: 797210:HALXA_RS18210
uniprot id: F8DDA9
names: Similarity
messages: Belongs to the TPP enzyme family.

797210:HALXA RS14860
gene id: 797210:HALXA_RS14860
uniprot id: F8DB35
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS08395
gene id: 797210:HALXA_RS08395
uniprot id: F8DAS4
names: Function
names: Similarity
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

797210:HALXA RS10540
gene id: 797210:HALXA_RS10540
uniprot id: F8D448
names: Similarity
messages: Belongs to the peptidase M24B family.

797210:HALXA RS09935
gene id: 797210:HALXA_RS09935
uniprot id: F8D340
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS01125
gene id: 797210:HALXA_RS01125
uniprot id: F8D8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797210:HALXA RS18395
gene id: 797210:HALXA_RS18395
uniprot id: F8DDE6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS11195
gene id: 797210:HALXA_RS11195
uniprot id: F8D4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm

797210:HALXA RS13160
gene id: 797210:HALXA_RS13160
uniprot id: F8D8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS19180
gene id: 797210:HALXA_RS19180
uniprot id: F8DDT8
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS18740
gene id: 797210:HALXA_RS18740
uniprot id: F8DDK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS15805
gene id: 797210:HALXA_RS15805
uniprot id: F8D378
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS12775
gene id: 797210:HALXA_RS12775
uniprot id: F8D815
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS01565
gene id: 797210:HALXA_RS01565
uniprot id: F8D942
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

797210:HALXA RS14145
gene id: 797210:HALXA_RS14145
uniprot id: F8DA97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
messages: Homotetramer.

797210:HALXA RS10860
gene id: 797210:HALXA_RS10860
uniprot id: F8D4A5
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS08265
gene id: 797210:HALXA_RS08265
uniprot id: F8DAP9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

797210:HALXA RS10900
gene id: 797210:HALXA_RS10900
uniprot id: F8D4Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. DGGGP synthase subfamily.
messages: Cell membrane
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

797210:HALXA RS03640
gene id: 797210:HALXA_RS03640
uniprot id: F8DCL6
names: Similarity
messages: Belongs to the aspartokinase family.

797210:HALXA RS13465
gene id: 797210:HALXA_RS13465
uniprot id: F8D8W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

797210:HALXA RS13455
gene id: 797210:HALXA_RS13455
uniprot id: F8D8W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

797210:HALXA RS08825
gene id: 797210:HALXA_RS08825
uniprot id: F8DBI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS08575
gene id: 797210:HALXA_RS08575
uniprot id: F8D8Y1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS07085
gene id: 797210:HALXA_RS07085
uniprot id: F8D800
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

797210:HALXA RS07325
gene id: 797210:HALXA_RS07325
uniprot id: F8D8N8
names: Function
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
messages: May catalyze a purine salvage reaction, the substrate is unknown.

797210:HALXA RS07125
gene id: 797210:HALXA_RS07125
uniprot id: F8D8J9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

797210:HALXA RS18135
gene id: 797210:HALXA_RS18135
uniprot id: F8DD94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS14550
gene id: 797210:HALXA_RS14550
uniprot id: F8DB29
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

797210:HALXA RS00580
gene id: 797210:HALXA_RS00580
uniprot id: F8D712
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS07790
gene id: 797210:HALXA_RS07790
uniprot id: F8D9E6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

797210:HALXA RS18215
gene id: 797210:HALXA_RS18215
uniprot id: F8DDB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

797210:HALXA RS02885
gene id: 797210:HALXA_RS02885
uniprot id: F8DBC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

797210:HALXA RS05250
gene id: 797210:HALXA_RS05250
uniprot id: F8D4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

797210:HALXA RS18020
gene id: 797210:HALXA_RS18020
uniprot id: F8DE00
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS01925
gene id: 797210:HALXA_RS01925
uniprot id: F8D9U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS03280
gene id: 797210:HALXA_RS03280
uniprot id: F8DC10
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

797210:HALXA RS15500
gene id: 797210:HALXA_RS15500
uniprot id: F8DCY0
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS13470
gene id: 797210:HALXA_RS13470
uniprot id: F8D8W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

797210:HALXA RS02500
gene id: 797210:HALXA_RS02500
uniprot id: F8DAM4
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS06310
gene id: 797210:HALXA_RS06310
uniprot id: F8D6J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Cytoplasm

797210:HALXA RS12255
gene id: 797210:HALXA_RS12255
uniprot id: F8D6Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS16645
gene id: 797210:HALXA_RS16645
uniprot id: F8D4D9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

797210:HALXA RS06780
gene id: 797210:HALXA_RS06780
uniprot id: F8D7U8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

797210:HALXA RS13900
gene id: 797210:HALXA_RS13900
uniprot id: F8D9N1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

797210:HALXA RS18680
gene id: 797210:HALXA_RS18680
uniprot id: F8DDK0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

797210:HALXA RS13945
gene id: 797210:HALXA_RS13945
uniprot id: F8DA63
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS05700
gene id: 797210:HALXA_RS05700
uniprot id: F8D5P5
names: Similarity
messages: Belongs to the PdaD family.

797210:HALXA RS07600
gene id: 797210:HALXA_RS07600
uniprot id: F8D9B2
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS07740
gene id: 797210:HALXA_RS07740
uniprot id: F8D9D5
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS12425
gene id: 797210:HALXA_RS12425
uniprot id: F8D7B7
names: Similarity
messages: Belongs to the Dps family.

797210:HALXA RS00355
gene id: 797210:HALXA_RS00355
uniprot id: F8D658
names: Similarity
messages: Belongs to the archease family.

797210:HALXA RS11790
gene id: 797210:HALXA_RS11790
uniprot id: F8D9R6
names: Similarity
messages: Belongs to the SCO1/2 family.

797210:HALXA RS15310
gene id: 797210:HALXA_RS15310
uniprot id: F8DCF0
names: Similarity
messages: Belongs to the glutamate synthase family.

797210:HALXA RS17615
gene id: 797210:HALXA_RS17615
uniprot id: F8D617
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

797210:HALXA RS06680
gene id: 797210:HALXA_RS06680
uniprot id: F8D791
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS13965
gene id: 797210:HALXA_RS13965
uniprot id: F8DA67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

797210:HALXA RS13040
gene id: 797210:HALXA_RS13040
uniprot id: F8D862
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

797210:HALXA RS08255
gene id: 797210:HALXA_RS08255
uniprot id: F8DAP7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

797210:HALXA RS06390
gene id: 797210:HALXA_RS06390
uniprot id: F8D739
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

797210:HALXA RS16410
gene id: 797210:HALXA_RS16410
uniprot id: F8D3W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Degrades polypeptides processively.
messages: Belongs to the peptidase S16 family. Archaeal LonB subfamily.
messages: Cell membrane
messages: Homohexamer. Organized in a ring with a central cavity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797210:HALXA RS18655
gene id: 797210:HALXA_RS18655
uniprot id: F8DDJ5
names: Similarity
messages: Belongs to the asparaginase 1 family.

797210:HALXA RS07880
gene id: 797210:HALXA_RS07880
uniprot id: F8D9Y9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

797210:HALXA RS07220
gene id: 797210:HALXA_RS07220
uniprot id: F8D8L9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

797210:HALXA RS18030
gene id: 797210:HALXA_RS18030
uniprot id: F8DD73
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

797210:HALXA RS07340
gene id: 797210:HALXA_RS07340
uniprot id: F8D8P0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797210:HALXA RS03005
gene id: 797210:HALXA_RS03005
uniprot id: F8DBV3
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

797210:HALXA RS14605
gene id: 797210:HALXA_RS14605
uniprot id: F8DB14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

797210:HALXA RS11460
gene id: 797210:HALXA_RS11460
uniprot id: F8D5D4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS00780
gene id: 797210:HALXA_RS00780
uniprot id: F8D7N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS13155
gene id: 797210:HALXA_RS13155
uniprot id: F8D8S2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS05995
gene id: 797210:HALXA_RS05995
uniprot id: F8D7M1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofG family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

797210:HALXA RS03000
gene id: 797210:HALXA_RS03000
uniprot id: F8DBV2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

797210:HALXA RS07590
gene id: 797210:HALXA_RS07590
uniprot id: F8D9B0
names: Subcellular Location Annotation
messages: Cell membrane

797210:HALXA RS12000
gene id: 797210:HALXA_RS12000
uniprot id: F8D6K9
names: Similarity
messages: Belongs to the FUN14 family.

797210:HALXA RS11245
gene id: 797210:HALXA_RS11245
uniprot id: F8D4W4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS18745
gene id: 797210:HALXA_RS18745
uniprot id: F8DDK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS10760
gene id: 797210:HALXA_RS10760
uniprot id: F8D487
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

797210:HALXA RS01225
gene id: 797210:HALXA_RS01225
uniprot id: F8D8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

797210:HALXA RS01195
gene id: 797210:HALXA_RS01195
uniprot id: F8D8E5
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS08590
gene id: 797210:HALXA_RS08590
uniprot id: F8D8Y2
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.

797210:HALXA RS18490
gene id: 797210:HALXA_RS18490
uniprot id: F8DDG2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797210:HALXA RS01705
gene id: 797210:HALXA_RS01705
uniprot id: F8D6T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

797210:HALXA RS12100
gene id: 797210:HALXA_RS12100
uniprot id: F8D6M9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS00245
gene id: 797210:HALXA_RS00245
uniprot id: F8D6C5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

797210:HALXA RS13590
gene id: 797210:HALXA_RS13590
uniprot id: F8D9H6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

797210:HALXA RS15685
gene id: 797210:HALXA_RS15685
uniprot id: F8DD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS13700
gene id: 797210:HALXA_RS13700
uniprot id: F8D9J9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS08415
gene id: 797210:HALXA_RS08415
uniprot id: F8DAS8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

797210:HALXA RS15840
gene id: 797210:HALXA_RS15840
uniprot id: F8D385
names: Similarity
messages: Belongs to the peptidase S49 family.

797210:HALXA RS04395
gene id: 797210:HALXA_RS04395
uniprot id: F8D7I1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

797210:HALXA RS14315
gene id: 797210:HALXA_RS14315
uniprot id: F8DAW6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

797210:HALXA RS04810
gene id: 797210:HALXA_RS04810
uniprot id: F8D433
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.

797210:HALXA RS15680
gene id: 797210:HALXA_RS15680
uniprot id: F8DD12
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS16910
gene id: 797210:HALXA_RS16910
uniprot id: F8D4X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS03385
gene id: 797210:HALXA_RS03385
uniprot id: F8DCG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

797210:HALXA RS14735
gene id: 797210:HALXA_RS14735
uniprot id: F8DBM4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

797210:HALXA RS05150
gene id: 797210:HALXA_RS05150
uniprot id: F8D4N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797210:HALXA RS13175
gene id: 797210:HALXA_RS13175
uniprot id: F8D8S6
names: Similarity
messages: Belongs to the transcriptional regulator TrmB family.

797210:HALXA RS00105
gene id: 797210:HALXA_RS00105
uniprot id: F8D698
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS07840
gene id: 797210:HALXA_RS07840
uniprot id: F8D9F5
names: Subunit
messages: Homotetramer.

797210:HALXA RS03410
gene id: 797210:HALXA_RS03410
uniprot id: F8DCH2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

797210:HALXA RS15395
gene id: 797210:HALXA_RS15395
uniprot id: F8DCW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

797210:HALXA RS19220
gene id: 797210:HALXA_RS19220
uniprot id: F8DDU6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

797210:HALXA RS03190
gene id: 797210:HALXA_RS03190
uniprot id: F8DBZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

797210:HALXA RS01890
gene id: 797210:HALXA_RS01890
uniprot id: F8D9T3
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
messages: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.

797210:HALXA RS03870
gene id: 797210:HALXA_RS03870
uniprot id: F8D2W5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

797210:HALXA RS16305
gene id: 797210:HALXA_RS16305
uniprot id: F8DB67
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS04590
gene id: 797210:HALXA_RS04590
uniprot id: F8D401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

797210:HALXA RS06635
gene id: 797210:HALXA_RS06635
uniprot id: F8D783
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797210:HALXA RS02470
gene id: 797210:HALXA_RS02470
uniprot id: F8DAL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS08615
gene id: 797210:HALXA_RS08615
uniprot id: F8DBE4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

797210:HALXA RS03020
gene id: 797210:HALXA_RS03020
uniprot id: F8DBV6
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

797210:HALXA RS09490
gene id: 797210:HALXA_RS09490
uniprot id: F8DCR1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS01615
gene id: 797210:HALXA_RS01615
uniprot id: F8D952
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

797210:HALXA RS13980
gene id: 797210:HALXA_RS13980
uniprot id: F8DA70
names: Function
names: Subunit
messages: Interacts with chemotaxis (Che) proteins as well as flagella accessory (Fla) proteins.
messages: Involved in taxis signal transduction.

797210:HALXA RS12850
gene id: 797210:HALXA_RS12850
uniprot id: F8D830
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS15315
gene id: 797210:HALXA_RS15315
uniprot id: F8DCF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS13520
gene id: 797210:HALXA_RS13520
uniprot id: F8D9G3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M54 family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.
messages: Monomer.
messages: Probable zinc metalloprotease whose natural substrate is unknown.

797210:HALXA RS07820
gene id: 797210:HALXA_RS07820
uniprot id: F8D9F1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS11160
gene id: 797210:HALXA_RS11160
uniprot id: F8D4V1
names: Similarity
messages: Belongs to the UPF0047 family.

797210:HALXA RS04360
gene id: 797210:HALXA_RS04360
uniprot id: F8D3I2
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

797210:HALXA RS05685
gene id: 797210:HALXA_RS05685
uniprot id: F8D5P2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797210:HALXA RS06910
gene id: 797210:HALXA_RS06910
uniprot id: F8D7X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

797210:HALXA RS00255
gene id: 797210:HALXA_RS00255
uniprot id: F8D6C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797210:HALXA RS00085
gene id: 797210:HALXA_RS00085
uniprot id: F8D695
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

797210:HALXA RS02490
gene id: 797210:HALXA_RS02490
uniprot id: F8DAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

797210:HALXA RS10245
gene id: 797210:HALXA_RS10245
uniprot id: F8D3M4
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

797210:HALXA RS09640
gene id: 797210:HALXA_RS09640
uniprot id: F8DCT8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS09635
gene id: 797210:HALXA_RS09635
uniprot id: F8D903
names: Similarity
messages: Belongs to the DeoC/FbaB aldolase family.

797210:HALXA RS05650
gene id: 797210:HALXA_RS05650
uniprot id: F8D5N5
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

797210:HALXA RS16070
gene id: 797210:HALXA_RS16070
uniprot id: F8D3C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

797210:HALXA RS19260
gene id: 797210:HALXA_RS19260
uniprot id: F8DDV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

797210:HALXA RS13365
gene id: 797210:HALXA_RS13365
uniprot id: F8D8V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.
messages: Cytoplasm

797210:HALXA RS06490
gene id: 797210:HALXA_RS06490
uniprot id: F8D756
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS19410
gene id: 797210:HALXA_RS19410
uniprot id: F8DDY1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS03960
gene id: 797210:HALXA_RS03960
uniprot id: F8D2Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS15505
gene id: 797210:HALXA_RS15505
uniprot id: F8DCY1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS09410
gene id: 797210:HALXA_RS09410
uniprot id: F8DCP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

797210:HALXA RS01210
gene id: 797210:HALXA_RS01210
uniprot id: F8D8E8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

797210:HALXA RS01710
gene id: 797210:HALXA_RS01710
uniprot id: F8D966
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797210:HALXA RS04370
gene id: 797210:HALXA_RS04370
uniprot id: F8D3I3
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797210:HALXA RS00915
gene id: 797210:HALXA_RS00915
uniprot id: F8D7R4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

797210:HALXA RS01185
gene id: 797210:HALXA_RS01185
uniprot id: F8D8E3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

797210:HALXA RS13325
gene id: 797210:HALXA_RS13325
uniprot id: F8D8V0
names: Similarity
messages: Belongs to the SUI1 family.

797210:HALXA RS08405
gene id: 797210:HALXA_RS08405
uniprot id: F8DAS6
names: Similarity
messages: Belongs to the peptidase S8 family.

797210:HALXA RS18750
gene id: 797210:HALXA_RS18750
uniprot id: F8DDL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS04695
gene id: 797210:HALXA_RS04695
uniprot id: F8D421
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

797210:HALXA RS04650
gene id: 797210:HALXA_RS04650
uniprot id: F8D413
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS02845
gene id: 797210:HALXA_RS02845
uniprot id: F8DBB9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS07045
gene id: 797210:HALXA_RS07045
uniprot id: F8D7Z6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

797210:HALXA RS08550
gene id: 797210:HALXA_RS08550
uniprot id: F8DAV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS12125
gene id: 797210:HALXA_RS12125
uniprot id: F8D6N4
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS08420
gene id: 797210:HALXA_RS08420
uniprot id: F8DAS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

797210:HALXA RS15475
gene id: 797210:HALXA_RS15475
uniprot id: F8DCX5
names: Similarity
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.

797210:HALXA RS20280
gene id: 797210:HALXA_RS20280
uniprot id: F8DEG4
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS13015
gene id: 797210:HALXA_RS13015
uniprot id: F8D858
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

797210:HALXA RS12755
gene id: 797210:HALXA_RS12755
uniprot id: F8D811
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

797210:HALXA RS00210
gene id: 797210:HALXA_RS00210
uniprot id: F8D6B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

797210:HALXA RS12440
gene id: 797210:HALXA_RS12440
uniprot id: F8D7C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

797210:HALXA RS02220
gene id: 797210:HALXA_RS02220
uniprot id: F8D9Y8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS04100
gene id: 797210:HALXA_RS04100
uniprot id: F8D3D0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 zinc ion.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

797210:HALXA RS05020
gene id: 797210:HALXA_RS05020
uniprot id: F8D4K8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

797210:HALXA RS03795
gene id: 797210:HALXA_RS03795
uniprot id: F8D2V0
names: Function
names: Similarity
messages: Belongs to the archaeal IMP cyclohydrolase family.
messages: Catalyzes the cyclization of 5-formylamidoimidazole-4-carboxamide ribonucleotide to IMP.

797210:HALXA RS20220
gene id: 797210:HALXA_RS20220
uniprot id: F8DEC3
names: Similarity
messages: Belongs to the glutaredoxin family.

797210:HALXA RS14430
gene id: 797210:HALXA_RS14430
uniprot id: F8DAY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Involved in protein export.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the protein translocation apparatus. Forms a complex with SecD.

797210:HALXA RS16315
gene id: 797210:HALXA_RS16315
uniprot id: F8DB68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

797210:HALXA RS07920
gene id: 797210:HALXA_RS07920
uniprot id: F8D9Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

797210:HALXA RS16840
gene id: 797210:HALXA_RS16840
uniprot id: F8D4H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

797210:HALXA RS10445
gene id: 797210:HALXA_RS10445
uniprot id: F8D9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

797210:HALXA RS01695
gene id: 797210:HALXA_RS01695
uniprot id: F8D964
names: Similarity
messages: Belongs to the UPF0045 family.

797210:HALXA RS09730
gene id: 797210:HALXA_RS09730
uniprot id: F8DCV4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797210:HALXA RS20385
gene id: 797210:HALXA_RS20385
uniprot id: F8DEG9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

797210:HALXA RS01235
gene id: 797210:HALXA_RS01235
uniprot id: F8D8F3
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS05410
gene id: 797210:HALXA_RS05410
uniprot id: F8D560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

797210:HALXA RS11125
gene id: 797210:HALXA_RS11125
uniprot id: F8D4U6
names: Similarity
messages: Belongs to the UPF0179 family.

797210:HALXA RS09385
gene id: 797210:HALXA_RS09385
uniprot id: F8DCP0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

797210:HALXA RS16365
gene id: 797210:HALXA_RS16365
uniprot id: F8DB73
names: Similarity
messages: Belongs to the TrpC family.

797210:HALXA RS07265
gene id: 797210:HALXA_RS07265
uniprot id: F8D8M8
names: Similarity
messages: Belongs to the Nth/MutY family.

797210:HALXA RS14585
gene id: 797210:HALXA_RS14585
uniprot id: F8DB11
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

797210:HALXA RS17290
gene id: 797210:HALXA_RS17290
uniprot id: F8D5H1
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

797210:HALXA RS10750
gene id: 797210:HALXA_RS10750
uniprot id: F8D486
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

797210:HALXA RS19780
gene id: 797210:HALXA_RS19780
uniprot id: F8DE44
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS06620
gene id: 797210:HALXA_RS06620
uniprot id: F8D780
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

797210:HALXA RS05785
gene id: 797210:HALXA_RS05785
uniprot id: F8D5R2
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

797210:HALXA RS10255
gene id: 797210:HALXA_RS10255
uniprot id: F8D3M6
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

797210:HALXA RS06675
gene id: 797210:HALXA_RS06675
uniprot id: F8D790
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS00785
gene id: 797210:HALXA_RS00785
uniprot id: F8D7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS01650
gene id: 797210:HALXA_RS01650
uniprot id: F8D959
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

797210:HALXA RS17760
gene id: 797210:HALXA_RS17760
uniprot id: F8D644
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

797210:HALXA RS08930
gene id: 797210:HALXA_RS08930
uniprot id: F8DBJ8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

797210:HALXA RS22645
gene id: 797210:HALXA_RS22645
uniprot id: F8D7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P(II) protein family.
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

797210:HALXA RS15980
gene id: 797210:HALXA_RS15980
uniprot id: F8D3A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

797210:HALXA RS17320
gene id: 797210:HALXA_RS17320
uniprot id: F8D5H7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

797210:HALXA RS08955
gene id: 797210:HALXA_RS08955
uniprot id: F8DBK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

797210:HALXA RS00340
gene id: 797210:HALXA_RS00340
uniprot id: F8D6D6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

797210:HALXA RS09245
gene id: 797210:HALXA_RS09245
uniprot id: F8DC70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

797210:HALXA RS19325
gene id: 797210:HALXA_RS19325
uniprot id: F8DDW4
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797210:HALXA RS12795
gene id: 797210:HALXA_RS12795
uniprot id: F8D819
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

797210:HALXA RS06000
gene id: 797210:HALXA_RS06000
uniprot id: F8D7M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

797210:HALXA RS17180
gene id: 797210:HALXA_RS17180
uniprot id: F8D520
names: Caution
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS16845
gene id: 797210:HALXA_RS16845
uniprot id: F8D4H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

797210:HALXA RS00545
gene id: 797210:HALXA_RS00545
uniprot id: F8D704
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

797210:HALXA RS06580
gene id: 797210:HALXA_RS06580
uniprot id: F8D773
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

797210:HALXA RS13120
gene id: 797210:HALXA_RS13120
uniprot id: F8D8R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

797210:HALXA RS13425
gene id: 797210:HALXA_RS13425
uniprot id: F8D8W3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

797210:HALXA RS15140
gene id: 797210:HALXA_RS15140
uniprot id: F8DCB8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS10640
gene id: 797210:HALXA_RS10640
uniprot id: F8D468
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

797210:HALXA RS12845
gene id: 797210:HALXA_RS12845
uniprot id: F8D829
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

797210:HALXA RS01820
gene id: 797210:HALXA_RS01820
uniprot id: F8D985
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS08940
gene id: 797210:HALXA_RS08940
uniprot id: F8DBK0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

797210:HALXA RS03480
gene id: 797210:HALXA_RS03480
uniprot id: F8DCI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

797210:HALXA RS04615
gene id: 797210:HALXA_RS04615
uniprot id: F8D406
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

797210:HALXA RS07240
gene id: 797210:HALXA_RS07240
uniprot id: F8D8M3
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS01995
gene id: 797210:HALXA_RS01995
uniprot id: F8D9V4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

797210:HALXA RS03325
gene id: 797210:HALXA_RS03325
uniprot id: F8DC17
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

797210:HALXA RS04000
gene id: 797210:HALXA_RS04000
uniprot id: F8D2Y8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

797210:HALXA RS04425
gene id: 797210:HALXA_RS04425
uniprot id: F8D7I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

797210:HALXA RS06650
gene id: 797210:HALXA_RS06650
uniprot id: F8D884
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

797210:HALXA RS04585
gene id: 797210:HALXA_RS04585
uniprot id: F8D400
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS18465
gene id: 797210:HALXA_RS18465
uniprot id: F8DDF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

797210:HALXA RS01625
gene id: 797210:HALXA_RS01625
uniprot id: F8D954
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

797210:HALXA RS01660
gene id: 797210:HALXA_RS01660
uniprot id: F8D960
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

797210:HALXA RS13645
gene id: 797210:HALXA_RS13645
uniprot id: F8D9I7
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS04305
gene id: 797210:HALXA_RS04305
uniprot id: F8D3H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

797210:HALXA RS18280
gene id: 797210:HALXA_RS18280
uniprot id: F8DDC4
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS01425
gene id: 797210:HALXA_RS01425
uniprot id: F8D8I9
names: Similarity
messages: Belongs to the AAA ATPase family.

797210:HALXA RS19150
gene id: 797210:HALXA_RS19150
uniprot id: F8DDT3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

797210:HALXA RS13130
gene id: 797210:HALXA_RS13130
uniprot id: F8D8R7
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS08650
gene id: 797210:HALXA_RS08650
uniprot id: F8DBF1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

797210:HALXA RS12660
gene id: 797210:HALXA_RS12660
uniprot id: F8D7G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

797210:HALXA RS09275
gene id: 797210:HALXA_RS09275
uniprot id: F8DC75
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

797210:HALXA RS00515
gene id: 797210:HALXA_RS00515
uniprot id: F8D6Z8
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

797210:HALXA RS02810
gene id: 797210:HALXA_RS02810
uniprot id: F8DBB4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

797210:HALXA RS10800
gene id: 797210:HALXA_RS10800
uniprot id: F8D9P6
names: Similarity
messages: Belongs to the UPF0440 family.

797210:HALXA RS12855
gene id: 797210:HALXA_RS12855
uniprot id: F8D831
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS18725
gene id: 797210:HALXA_RS18725
uniprot id: F8DDK6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

797210:HALXA RS19215
gene id: 797210:HALXA_RS19215
uniprot id: F8DDU5
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS01845
gene id: 797210:HALXA_RS01845
uniprot id: F8D989
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

797210:HALXA RS06880
gene id: 797210:HALXA_RS06880
uniprot id: F8D7W9
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

797210:HALXA RS15975
gene id: 797210:HALXA_RS15975
uniprot id: F8DB61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS17230
gene id: 797210:HALXA_RS17230
uniprot id: F8D528
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

797210:HALXA RS16215
gene id: 797210:HALXA_RS16215
uniprot id: F8D3T8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

797210:HALXA RS06845
gene id: 797210:HALXA_RS06845
uniprot id: F8D7W1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

797210:HALXA RS16640
gene id: 797210:HALXA_RS16640
uniprot id: F8D4D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

797210:HALXA RS01725
gene id: 797210:HALXA_RS01725
uniprot id: F8D969
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

797210:HALXA RS16965
gene id: 797210:HALXA_RS16965
uniprot id: F8D4Y3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

797210:HALXA RS15715
gene id: 797210:HALXA_RS15715
uniprot id: F8DB57
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

797210:HALXA RS00920
gene id: 797210:HALXA_RS00920
uniprot id: F8D7R5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS18315
gene id: 797210:HALXA_RS18315
uniprot id: F8DDD1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS16065
gene id: 797210:HALXA_RS16065
uniprot id: F8DB65
names: Similarity
messages: Belongs to the Nudix hydrolase family.

797210:HALXA RS12160
gene id: 797210:HALXA_RS12160
uniprot id: F8D6P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

797210:HALXA RS06690
gene id: 797210:HALXA_RS06690
uniprot id: F8D885
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

797210:HALXA RS01560
gene id: 797210:HALXA_RS01560
uniprot id: F8D941
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

797210:HALXA RS18265
gene id: 797210:HALXA_RS18265
uniprot id: F8DDC0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

797210:HALXA RS18635
gene id: 797210:HALXA_RS18635
uniprot id: F8DDJ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

797210:HALXA RS03600
gene id: 797210:HALXA_RS03600
uniprot id: F8DCK9
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

797210:HALXA RS00670
gene id: 797210:HALXA_RS00670
uniprot id: F8D663
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.
messages: Cytoplasm
messages: Gas vesicle
messages: Vesicle

797210:HALXA RS11520
gene id: 797210:HALXA_RS11520
uniprot id: F8D5E3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS06180
gene id: 797210:HALXA_RS06180
uniprot id: F8D6H5
names: Subcellular Location Annotation
messages: Cytoplasm

797210:HALXA RS03660
gene id: 797210:HALXA_RS03660
uniprot id: F8DCM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

797210:HALXA RS02790
gene id: 797210:HALXA_RS02790
uniprot id: F8DBB0
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

797210:HALXA RS16675
gene id: 797210:HALXA_RS16675
uniprot id: F8D4E3
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

797210:HALXA RS03420
gene id: 797210:HALXA_RS03420
uniprot id: F8DCH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

797210:HALXA RS03615
gene id: 797210:HALXA_RS03615
uniprot id: F8DCL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

797210:HALXA RS00295
gene id: 797210:HALXA_RS00295
uniprot id: F8D654
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

797210:HALXA RS06795
gene id: 797210:HALXA_RS06795
uniprot id: F8D7V1
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS01555
gene id: 797210:HALXA_RS01555
uniprot id: F8D940
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

797210:HALXA RS03485
gene id: 797210:HALXA_RS03485
uniprot id: F8DCI7
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS12860
gene id: 797210:HALXA_RS12860
uniprot id: F8D832
names: Subcellular Location Annotation
messages: Membrane

797210:HALXA RS00250
gene id: 797210:HALXA_RS00250
uniprot id: F8D6C6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

797210:HALXA RS05200
gene id: 797210:HALXA_RS05200
uniprot id: F8D4N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

797210:HALXA RS14530
gene id: 797210:HALXA_RS14530
uniprot id: F8DB04
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

797210:HALXA RS15470
gene id: 797210:HALXA_RS15470
uniprot id: F8DCX4
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

797210:HALXA RS16860
gene id: 797210:HALXA_RS16860
uniprot id: F8D4H6
names: Similarity
messages: Belongs to the peptidase S1C family.