7918:LOC102693266
gene id: 7918:LOC102693266
uniprot id: W5NF75
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:LOC102693016
gene id: 7918:LOC102693016
uniprot id: W5MZ06
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

7918:LOC102683375
gene id: 7918:LOC102683375
uniprot id: W5N8V8
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:amer3
gene id: 7918:amer3
uniprot id: W5NLK9
names: Similarity
messages: Belongs to the Amer family.

7918:LOC107075434
gene id: 7918:LOC107075434
uniprot id: W5MD26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

7918:cdc14b
gene id: 7918:cdc14b
uniprot id: W5MS44
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

7918:hgh1
gene id: 7918:hgh1
uniprot id: W5MKZ8
names: Similarity
messages: Belongs to the HGH1 family.

7918:vgll4
gene id: 7918:vgll4
uniprot id: W5N961
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

7918:LOC102683469
gene id: 7918:LOC102683469
uniprot id: W5NF65
names: Similarity
messages: Belongs to the peptidase C2 family.

7918:gja8
gene id: 7918:gja8
uniprot id: W5NMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:psmd7
gene id: 7918:psmd7
uniprot id: W5M8N4
names: Similarity
messages: Belongs to the peptidase M67A family.

7918:gli2
gene id: 7918:gli2
uniprot id: W5M1U9
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

7918:slc10a4
gene id: 7918:slc10a4
uniprot id: W5N9N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

7918:nudt19
gene id: 7918:nudt19
uniprot id: W5M0Q4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

7918:prkd1
gene id: 7918:prkd1
uniprot id: W5MTZ8
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

7918:slc17a9
gene id: 7918:slc17a9
uniprot id: W5MCB5
names: Subcellular Location Annotation
messages: Membrane

7918:abcg8
gene id: 7918:abcg8
uniprot id: W5NI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

7918:polr2k
gene id: 7918:polr2k
uniprot id: W5MU21
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

7918:polr3g
gene id: 7918:polr3g
uniprot id: W5M124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Nucleus

7918:LOC102696934
gene id: 7918:LOC102696934
uniprot id: W5MBI1
names: Subcellular Location Annotation
messages: Membrane

7918:tmem38b
gene id: 7918:tmem38b
uniprot id: W5MV13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

7918:LOC102683678
gene id: 7918:LOC102683678
uniprot id: W5NF92
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

7918:mina
gene id: 7918:mina
uniprot id: W5MCK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

7918:LOC102688329
gene id: 7918:LOC102688329
uniprot id: W5M4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

7918:LOC102693873
gene id: 7918:LOC102693873
uniprot id: W5N6R8
names: Similarity
messages: Belongs to the cornifelin family.

7918:ano2
gene id: 7918:ano2
uniprot id: W5NKC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

7918:vangl1
gene id: 7918:vangl1
uniprot id: W5MHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

7918:med26
gene id: 7918:med26
uniprot id: W5M082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

7918:sdhd
gene id: 7918:sdhd
uniprot id: W5MFZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

7918:clic4
gene id: 7918:clic4
uniprot id: W5M4E1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

7918:capn5
gene id: 7918:capn5
uniprot id: W5MI53
names: Similarity
messages: Belongs to the peptidase C2 family.

7918:ccnk
gene id: 7918:ccnk
uniprot id: W5MQE7
names: Similarity
messages: Belongs to the cyclin family.

7918:nup85
gene id: 7918:nup85
uniprot id: W5N750
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

7918:trpc7
gene id: 7918:trpc7
uniprot id: W5MZY7
names: Subcellular Location Annotation
messages: Membrane

7918:cdk5r1
gene id: 7918:cdk5r1
uniprot id: W5NN63
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

7918:ccdc39
gene id: 7918:ccdc39
uniprot id: W5LWV3
names: Similarity
messages: Belongs to the CCDC39 family.

7918:kiaa2013
gene id: 7918:kiaa2013
uniprot id: W5ME17
names: Subcellular Location Annotation
messages: Membrane

7918:mdfi
gene id: 7918:mdfi
uniprot id: W5N2T6
names: Similarity
messages: Belongs to the MDFI family.

7918:LOC107077521
gene id: 7918:LOC107077521
uniprot id: W5M3T7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:ppp2r2d
gene id: 7918:ppp2r2d
uniprot id: W5ML94
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

7918:st6galnac3
gene id: 7918:st6galnac3
uniprot id: W5M749
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:naa30
gene id: 7918:naa30
uniprot id: W5MZ73
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

7918:LOC102685996
gene id: 7918:LOC102685996
uniprot id: W5MUL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

7918:serpinf1
gene id: 7918:serpinf1
uniprot id: W5MH36
names: Similarity
messages: Belongs to the serpin family.

7918:plppr1
gene id: 7918:plppr1
uniprot id: W5M4G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

7918:homer3
gene id: 7918:homer3
uniprot id: W5M289
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

7918:nemf
gene id: 7918:nemf
uniprot id: W5N0E0
names: Similarity
messages: Belongs to the NEMF family.

7918:cnot7
gene id: 7918:cnot7
uniprot id: W5N974
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

7918:phkb
gene id: 7918:phkb
uniprot id: W5MDG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

7918:def8
gene id: 7918:def8
uniprot id: W5LYX7
names: Similarity
messages: Belongs to the DEF8 family.

7918:LOC102698167
gene id: 7918:LOC102698167
uniprot id: W5M3A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

7918:cnot11
gene id: 7918:cnot11
uniprot id: W5MX52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

7918:prep
gene id: 7918:prep
uniprot id: W5NIG1
names: Similarity
messages: Belongs to the peptidase S9A family.

7918:wnt11
gene id: 7918:wnt11
uniprot id: W5MBG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:gas6
gene id: 7918:gas6
uniprot id: W5MUX6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:synpr
gene id: 7918:synpr
uniprot id: W5MWE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

7918:vps54
gene id: 7918:vps54
uniprot id: W5NGM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

7918:sdhaf3
gene id: 7918:sdhaf3
uniprot id: W5MYR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

7918:ndp
gene id: 7918:ndp
uniprot id: W5M1N2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:chrna9
gene id: 7918:chrna9
uniprot id: W5N5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:rnf10
gene id: 7918:rnf10
uniprot id: W5M502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

7918:rab14
gene id: 7918:rab14
uniprot id: W5ME44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

7918:dnase1l3
gene id: 7918:dnase1l3
uniprot id: W5N6M1
names: Similarity
messages: Belongs to the DNase I family.

7918:mex3b
gene id: 7918:mex3b
uniprot id: W5N5B8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:LOC102694683
gene id: 7918:LOC102694683
uniprot id: W5MD74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

7918:ppp2r5a
gene id: 7918:ppp2r5a
uniprot id: W5NHU4
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

7918:yae1d1
gene id: 7918:yae1d1
uniprot id: W5MZS8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:spin1
gene id: 7918:spin1
uniprot id: W5MVW1
names: Similarity
messages: Belongs to the SPIN/STSY family.

7918:fam174a
gene id: 7918:fam174a
uniprot id: W5MRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

7918:poll
gene id: 7918:poll
uniprot id: W5N181
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus

7918:hn1l
gene id: 7918:hn1l
uniprot id: W5M283
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

7918:mst1r
gene id: 7918:mst1r
uniprot id: W5MY80
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:LOC102686972
gene id: 7918:LOC102686972
uniprot id: W5MRQ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:psma5
gene id: 7918:psma5
uniprot id: W5N3F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

7918:gpr183
gene id: 7918:gpr183
uniprot id: W5NML9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:glul
gene id: 7918:glul
uniprot id: W5MAD8
names: Similarity
messages: Belongs to the glutamine synthetase family.

7918:hspb1
gene id: 7918:hspb1
uniprot id: W5M4V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

7918:uts2b
gene id: 7918:uts2b
uniprot id: W5MCG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

7918:arf4
gene id: 7918:arf4
uniprot id: W5N6U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

7918:clg9h8orf82
gene id: 7918:clg9h8orf82
uniprot id: W5MPG9
names: Similarity
messages: Belongs to the UPF0598 family.

7918:ano1
gene id: 7918:ano1
uniprot id: W5MCV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:apool
gene id: 7918:apool
uniprot id: W5NCI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

7918:LOC102686206
gene id: 7918:LOC102686206
uniprot id: W5MDI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

7918:kremen1
gene id: 7918:kremen1
uniprot id: W5M5K8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:ireb2
gene id: 7918:ireb2
uniprot id: W5ND04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

7918:cog1
gene id: 7918:cog1
uniprot id: W5N403
uniprot id: W5N408
names: Similarity
messages: Belongs to the COG1 family.

7918:myt1l
gene id: 7918:myt1l
uniprot id: W5NKX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

7918:asz1
gene id: 7918:asz1
uniprot id: W5NEY2
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.

7918:cnot8
gene id: 7918:cnot8
uniprot id: W5N3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

7918:acp7
gene id: 7918:acp7
uniprot id: W5N439
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

7918:diras1
gene id: 7918:diras1
uniprot id: W5NM72
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:cldn11
gene id: 7918:cldn11
uniprot id: W5MKA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:ttc36
gene id: 7918:ttc36
uniprot id: W5MF64
names: Similarity
messages: Belongs to the TTC36 family.

7918:rbm17
gene id: 7918:rbm17
uniprot id: W5NF67
uniprot id: W5NF70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

7918:f13a1
gene id: 7918:f13a1
uniprot id: W5N161
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

7918:npy2r
gene id: 7918:npy2r
uniprot id: W5NNW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:wfikkn2
gene id: 7918:wfikkn2
uniprot id: W5MYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Secreted

7918:ankrd13c
gene id: 7918:ankrd13c
uniprot id: W5MV78
names: Subcellular Location Annotation
messages: Membrane

7918:mul1
gene id: 7918:mul1
uniprot id: W5M1X8
names: Subcellular Location Annotation
messages: Membrane

7918:elf3
gene id: 7918:elf3
uniprot id: W5N3W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:pofut1
gene id: 7918:pofut1
uniprot id: W5MF76
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

7918:dpysl4
gene id: 7918:dpysl4
uniprot id: W5ML29
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

7918:utp15
gene id: 7918:utp15
uniprot id: W5MYW0
names: Subcellular Location Annotation
messages: nucleolus

7918:LOC102693312
gene id: 7918:LOC102693312
uniprot id: W5MSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:agtr2
gene id: 7918:agtr2
uniprot id: W5NLR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

7918:LOC102685007
gene id: 7918:LOC102685007
uniprot id: W5LYL8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:tacc3
gene id: 7918:tacc3
uniprot id: W5MJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

7918:tmem263
gene id: 7918:tmem263
uniprot id: W5NDS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

7918:kcnk13
gene id: 7918:kcnk13
uniprot id: W5MRG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

7918:cse1l
gene id: 7918:cse1l
uniprot id: W5M5L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

7918:adm
gene id: 7918:adm
uniprot id: W5M7W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

7918:cdc42ep4
gene id: 7918:cdc42ep4
uniprot id: W5NMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

7918:hcn2
gene id: 7918:hcn2
uniprot id: W5MCZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

7918:peli1
gene id: 7918:peli1
uniprot id: W5NGL9
names: Similarity
messages: Belongs to the pellino family.

7918:chrnb3
gene id: 7918:chrnb3
uniprot id: W5N546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:n6amt2
gene id: 7918:n6amt2
uniprot id: W5MY99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

7918:cyld
gene id: 7918:cyld
uniprot id: W5MKF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

7918:dgcr14
gene id: 7918:dgcr14
uniprot id: W5MC14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

7918:rbbp5
gene id: 7918:rbbp5
uniprot id: W5N041
names: Subcellular Location Annotation
messages: Nucleus

7918:gphn
gene id: 7918:gphn
uniprot id: W5N9W0
names: Similarity
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

7918:nubp1
gene id: 7918:nubp1
uniprot id: W5MGB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

7918:mlh1
gene id: 7918:mlh1
uniprot id: W5MBU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

7918:LOC102693077
gene id: 7918:LOC102693077
uniprot id: W5NN19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:akt2
gene id: 7918:akt2
uniprot id: W5NBQ5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

7918:atp6v1e1
gene id: 7918:atp6v1e1
uniprot id: W5NIM7
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

7918:ccdc109b
gene id: 7918:ccdc109b
uniprot id: W5N393
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Membrane
messages: Mitochondrion inner membrane

7918:LOC102694185
gene id: 7918:LOC102694185
uniprot id: W5MQJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:sdc2
gene id: 7918:sdc2
uniprot id: W5M6M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

7918:tmtc4
gene id: 7918:tmtc4
uniprot id: W5M546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

7918:cyyr1
gene id: 7918:cyyr1
uniprot id: W5MXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYYR1 family.
messages: Membrane

7918:usp20
gene id: 7918:usp20
uniprot id: W5M8U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

7918:LOC102684429
gene id: 7918:LOC102684429
uniprot id: W5MBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

7918:kcng1
gene id: 7918:kcng1
uniprot id: W5M301
names: Subcellular Location Annotation
messages: Membrane

7918:shroom3
gene id: 7918:shroom3
uniprot id: W5M858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

7918:med7
gene id: 7918:med7
uniprot id: W5NP45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

7918:tars
gene id: 7918:tars
uniprot id: W5N068
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

7918:pou6f2
gene id: 7918:pou6f2
uniprot id: W5MZV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

7918:LOC102698487
gene id: 7918:LOC102698487
uniprot id: W5NES0
names: Similarity
messages: Belongs to the leptin family.

7918:cdc20
gene id: 7918:cdc20
uniprot id: W5M8J3
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

7918:LOC107080013
gene id: 7918:LOC107080013
uniprot id: W5NM31
names: Subunit
messages: Interacts with ATP6V0C.

7918:anp32e
gene id: 7918:anp32e
uniprot id: W5MQ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

7918:timm23
gene id: 7918:timm23
uniprot id: W5N5H2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

7918:hpn
gene id: 7918:hpn
uniprot id: W5M6U1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:htr2a
gene id: 7918:htr2a
uniprot id: W5MWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

7918:LOC102686607
gene id: 7918:LOC102686607
uniprot id: W5N8I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

7918:mpp7
gene id: 7918:mpp7
uniprot id: W5MKV5
names: Similarity
messages: Belongs to the MAGUK family.

7918:scarf2
gene id: 7918:scarf2
uniprot id: W5M7P5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:pde7b
gene id: 7918:pde7b
uniprot id: W5NH79
uniprot id: W5NH80
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:alg3
gene id: 7918:alg3
uniprot id: W5MFJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Belongs to the glycosyltransferase 58 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:LOC102682341
gene id: 7918:LOC102682341
uniprot id: W5NLM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:LOC102684340
gene id: 7918:LOC102684340
uniprot id: W5NMI2
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:phyhipl
gene id: 7918:phyhipl
uniprot id: W5MHP6
names: Similarity
messages: Belongs to the PHYHIP family.

7918:arrdc4
gene id: 7918:arrdc4
uniprot id: W5NAR7
names: Similarity
messages: Belongs to the arrestin family.

7918:chd7
gene id: 7918:chd7
uniprot id: W5MCI6
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

7918:trpv4
gene id: 7918:trpv4
uniprot id: W5M9P8
names: Subcellular Location Annotation
messages: Membrane

7918:med30
gene id: 7918:med30
uniprot id: W5M610
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

7918:LOC102690963
gene id: 7918:LOC102690963
uniprot id: W5M6L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

7918:fabp3
gene id: 7918:fabp3
uniprot id: W5MDC1
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

7918:tecr
gene id: 7918:tecr
uniprot id: W5MUV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:tcta
gene id: 7918:tcta
uniprot id: W5NAW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: Membrane

7918:nudt3
gene id: 7918:nudt3
uniprot id: W5MUV9
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

7918:slit3
gene id: 7918:slit3
uniprot id: W5N351
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:ccdc25
gene id: 7918:ccdc25
uniprot id: W5NJC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

7918:ube4a
gene id: 7918:ube4a
uniprot id: W5M8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

7918:nt5dc3
gene id: 7918:nt5dc3
uniprot id: W5NCW9
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

7918:tspan3
gene id: 7918:tspan3
uniprot id: W5NBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:irx1
gene id: 7918:irx1
uniprot id: W5MQU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

7918:mfsd8
gene id: 7918:mfsd8
uniprot id: W5MXJ5
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102687150
gene id: 7918:LOC102687150
uniprot id: W5MV20
names: Similarity
messages: Belongs to the dermatopontin family.

7918:LOC107078556
gene id: 7918:LOC107078556
uniprot id: W5LXY3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:LOC102692777
gene id: 7918:LOC102692777
uniprot id: W5MMQ0
names: Subcellular Location Annotation
messages: Membrane

7918:relt
gene id: 7918:relt
uniprot id: W5MGR4
names: Similarity
messages: Belongs to the RELT family.

7918:LOC102683457
gene id: 7918:LOC102683457
uniprot id: W5MUR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

7918:LOC102694791
gene id: 7918:LOC102694791
uniprot id: W5NB10
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

7918:ddx18
gene id: 7918:ddx18
uniprot id: W5M5L0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

7918:gipc2
gene id: 7918:gipc2
uniprot id: W5M852
names: Similarity
messages: Belongs to the GIPC family.

7918:agpat4
gene id: 7918:agpat4
uniprot id: W5NHB5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

7918:LOC107080026
gene id: 7918:LOC107080026
uniprot id: W5MIS6
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

7918:aff1
gene id: 7918:aff1
uniprot id: W5M8X5
names: Similarity
messages: Belongs to the AF4 family.

7918:pdp1
gene id: 7918:pdp1
uniprot id: W5NP85
names: Similarity
messages: Belongs to the PP2C family.

7918:LOC102682519
gene id: 7918:LOC102682519
uniprot id: W5MK93
names: Similarity
messages: Belongs to the BRINP family.

7918:LOC102696380
gene id: 7918:LOC102696380
uniprot id: W5LWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

7918:pcyt2
gene id: 7918:pcyt2
uniprot id: W5N4B0
names: Similarity
messages: Belongs to the cytidylyltransferase family.

7918:LOC102693938
gene id: 7918:LOC102693938
uniprot id: W5MTR1
names: Subcellular Location Annotation
messages: Membrane

7918:kiaa1147
gene id: 7918:kiaa1147
uniprot id: W5NIN9
names: Similarity
messages: Belongs to the DENND11 family.

7918:aco1
gene id: 7918:aco1
uniprot id: W5MZ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm

7918:serpind1
gene id: 7918:serpind1
uniprot id: W5M2R7
names: Similarity
messages: Belongs to the serpin family.

7918:mettl16
gene id: 7918:mettl16
uniprot id: W5MA84
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

7918:rgma
gene id: 7918:rgma
uniprot id: W5NAR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

7918:cul1
gene id: 7918:cul1
uniprot id: W5N742
names: Similarity
messages: Belongs to the cullin family.

7918:tm4sf4
gene id: 7918:tm4sf4
uniprot id: W5M0U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

7918:pik3r3
gene id: 7918:pik3r3
uniprot id: W5MEZ4
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

7918:kcnh5
gene id: 7918:kcnh5
uniprot id: W5MVS5
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102693769
gene id: 7918:LOC102693769
uniprot id: W5MM67
names: Similarity
messages: Belongs to the globin family.

7918:pthlh
gene id: 7918:pthlh
uniprot id: W5NIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

7918:flnb
gene id: 7918:flnb
uniprot id: W5N6Q9
names: Similarity
messages: Belongs to the filamin family.

7918:pitx3
gene id: 7918:pitx3
uniprot id: W5MTI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

7918:LOC102683980
gene id: 7918:LOC102683980
uniprot id: W5NDR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

7918:LOC102684283
gene id: 7918:LOC102684283
uniprot id: W5MCF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

7918:osgepl1
gene id: 7918:osgepl1
uniprot id: W5MQN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

7918:dbx2
gene id: 7918:dbx2
uniprot id: W5NI36
names: Subcellular Location Annotation
messages: Nucleus

7918:slc2a13
gene id: 7918:slc2a13
uniprot id: W5NGS7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

7918:faah2
gene id: 7918:faah2
uniprot id: W5MTA5
names: Similarity
messages: Belongs to the amidase family.

7918:ocel1
gene id: 7918:ocel1
uniprot id: W5M4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

7918:sod1
gene id: 7918:sod1
uniprot id: W5MS00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

7918:kcnj15
gene id: 7918:kcnj15
uniprot id: W5NNT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

7918:qsox2
gene id: 7918:qsox2
uniprot id: W5M8A0
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

7918:auh
gene id: 7918:auh
uniprot id: W5MNK4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

7918:gnpnat1
gene id: 7918:gnpnat1
uniprot id: W5N2K4
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

7918:manea
gene id: 7918:manea
uniprot id: W5NK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:rngtt
gene id: 7918:rngtt
uniprot id: W5NJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

7918:scpep1
gene id: 7918:scpep1
uniprot id: W5N8T8
names: Similarity
messages: Belongs to the peptidase S10 family.

7918:entpd2
gene id: 7918:entpd2
uniprot id: W5LXZ6
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

7918:oca2
gene id: 7918:oca2
uniprot id: W5MNW3
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102687681
gene id: 7918:LOC102687681
uniprot id: W5NA11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:gabrg2
gene id: 7918:gabrg2
uniprot id: W5MXI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:cilp
gene id: 7918:cilp
uniprot id: W5N8M3
names: Subcellular Location Annotation
messages: extracellular matrix

7918:b9d2
gene id: 7918:b9d2
uniprot id: W5N9Y9
names: Subcellular Location Annotation
messages: cilium basal body

7918:LOC102686073
gene id: 7918:LOC102686073
uniprot id: W5MXY8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

7918:rfc1
gene id: 7918:rfc1
uniprot id: W5N5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

7918:clg11h18orf21
gene id: 7918:clg11h18orf21
uniprot id: W5MJT1
names: Similarity
messages: Belongs to the UPF0711 family.

7918:gli3
gene id: 7918:gli3
uniprot id: W5N286
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

7918:pdpk1
gene id: 7918:pdpk1
uniprot id: W5M823
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

7918:snrpe
gene id: 7918:snrpe
uniprot id: W5N205
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

7918:ermn
gene id: 7918:ermn
uniprot id: W5MF39
names: Function
names: Subunit
messages: Binds actin.
messages: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

7918:mcu
gene id: 7918:mcu
uniprot id: W5MPZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

7918:LOC102686334
gene id: 7918:LOC102686334
uniprot id: W5N282
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

7918:emp3
gene id: 7918:emp3
uniprot id: W5LZF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:scn1b
gene id: 7918:scn1b
uniprot id: W5MC27
names: Subcellular Location Annotation
messages: Membrane

7918:gdi2
gene id: 7918:gdi2
uniprot id: W5NF56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

7918:ldlrad2
gene id: 7918:ldlrad2
uniprot id: W5M0W8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:rb1
gene id: 7918:rb1
uniprot id: W5MR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

7918:rhag
gene id: 7918:rhag
uniprot id: W5NHT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

7918:mettl4
gene id: 7918:mettl4
uniprot id: W5MYW1
names: Similarity
messages: Belongs to the MT-A70-like family.

7918:abcc12
gene id: 7918:abcc12
uniprot id: W5MDB7
names: Subcellular Location Annotation
messages: Membrane

7918:tgs1
gene id: 7918:tgs1
uniprot id: W5ME41
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

7918:ezr
gene id: 7918:ezr
uniprot id: W5NHV6
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

7918:ufd1l
gene id: 7918:ufd1l
uniprot id: W5M186
names: Similarity
messages: Belongs to the UFD1 family.

7918:acvr1b
gene id: 7918:acvr1b
uniprot id: W5MLK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

7918:tspan19
gene id: 7918:tspan19
uniprot id: W5NHR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:LOC102690973
gene id: 7918:LOC102690973
uniprot id: W5MPA1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

7918:stx5
gene id: 7918:stx5
uniprot id: W5LYU8
names: Similarity
messages: Belongs to the syntaxin family.

7918:fam124a
gene id: 7918:fam124a
uniprot id: W5MW51
names: Similarity
messages: Belongs to the FAM124 family.

7918:LOC102690995
gene id: 7918:LOC102690995
uniprot id: W5N3R3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

7918:kdm7a
gene id: 7918:kdm7a
uniprot id: W5NIZ4
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

7918:ctnnd2
gene id: 7918:ctnnd2
uniprot id: W5N7P2
names: Similarity
messages: Belongs to the beta-catenin family.

7918:slc6a9
gene id: 7918:slc6a9
uniprot id: W5M450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A9 subfamily.
messages: Cell membrane
messages: Membrane

7918:snx25
gene id: 7918:snx25
uniprot id: W5N8P0
names: Similarity
messages: Belongs to the sorting nexin family.

7918:stambpl1
gene id: 7918:stambpl1
uniprot id: W5MG26
names: Similarity
messages: Belongs to the peptidase M67C family.

7918:lamtor5
gene id: 7918:lamtor5
uniprot id: W5N188
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

7918:gnal
gene id: 7918:gnal
uniprot id: W5M2K7
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

7918:LOC102685321
gene id: 7918:LOC102685321
uniprot id: W5N4W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

7918:yif1b
gene id: 7918:yif1b
uniprot id: W5NBC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

7918:ctnnal1
gene id: 7918:ctnnal1
uniprot id: W5MK25
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

7918:LOC102691634
gene id: 7918:LOC102691634
uniprot id: W5N7J1
names: Subcellular Location Annotation
messages: Nucleus

7918:vrk1
gene id: 7918:vrk1
uniprot id: W5MQ84
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:arhgap32
gene id: 7918:arhgap32
uniprot id: W5MBP7
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

7918:ruvbl2
gene id: 7918:ruvbl2
uniprot id: W5M3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

7918:pth2
gene id: 7918:pth2
uniprot id: W5N9T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

7918:LOC102698789
gene id: 7918:LOC102698789
uniprot id: W5MH62
names: Similarity
messages: Belongs to the peptidase S10 family.

7918:trove2
gene id: 7918:trove2
uniprot id: W5MKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

7918:ppp3cb
gene id: 7918:ppp3cb
uniprot id: W5N0S3
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

7918:LOC102687850
gene id: 7918:LOC102687850
uniprot id: W5MVF0
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:fundc2
gene id: 7918:fundc2
uniprot id: W5N8P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

7918:ndufaf7
gene id: 7918:ndufaf7
uniprot id: W5NJP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

7918:prpf4
gene id: 7918:prpf4
uniprot id: W5LWY9
names: Subcellular Location Annotation
messages: Nucleus speckle

7918:slc8a3
gene id: 7918:slc8a3
uniprot id: W5N9K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

7918:adamts18
gene id: 7918:adamts18
uniprot id: W5MD96
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:eny2
gene id: 7918:eny2
uniprot id: W5M5D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

7918:fam19a3
gene id: 7918:fam19a3
uniprot id: W5MW08
names: Similarity
messages: Belongs to the TAFA family.

7918:unc45b
gene id: 7918:unc45b
uniprot id: W5MSU9
names: Subcellular Location Annotation
messages: A band
messages: Z line
messages: perinuclear region

7918:cnrip1
gene id: 7918:cnrip1
uniprot id: W5NGG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

7918:LOC102698619
gene id: 7918:LOC102698619
uniprot id: W5NAF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.

7918:pdcd4
gene id: 7918:pdcd4
uniprot id: W5N3D8
names: Similarity
messages: Belongs to the PDCD4 family.

7918:med10
gene id: 7918:med10
uniprot id: W5MQN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

7918:slc37a2
gene id: 7918:slc37a2
uniprot id: W5M2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

7918:acadvl
gene id: 7918:acadvl
uniprot id: W5NAS6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

7918:ola1
gene id: 7918:ola1
uniprot id: W5MKS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

7918:clg17h2orf40
gene id: 7918:clg17h2orf40
uniprot id: W5MQQ6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

7918:LOC102693960
gene id: 7918:LOC102693960
uniprot id: W5MPM3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

7918:cdk19
gene id: 7918:cdk19
uniprot id: W5NK51
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:LOC102689599
gene id: 7918:LOC102689599
uniprot id: W5MZV0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

7918:cntnap2
gene id: 7918:cntnap2
uniprot id: W5N797
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

7918:tmem27
gene id: 7918:tmem27
uniprot id: W5MLR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:clg17h11orf73
gene id: 7918:clg17h11orf73
uniprot id: W5MTL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

7918:mnat1
gene id: 7918:mnat1
uniprot id: W5MVG3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

7918:kcnj2
gene id: 7918:kcnj2
uniprot id: W5NMK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.
messages: Membrane

7918:tnrc6c
gene id: 7918:tnrc6c
uniprot id: W5N782
names: Similarity
messages: Belongs to the GW182 family.

7918:rasgrp3
gene id: 7918:rasgrp3
uniprot id: W5NJ19
names: Similarity
messages: Belongs to the RASGRP family.

7918:ednra
gene id: 7918:ednra
uniprot id: W5MQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

7918:msi2
gene id: 7918:msi2
uniprot id: W5MB40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

7918:ggnbp2
gene id: 7918:ggnbp2
uniprot id: W5M5Y0
names: Function
messages: May be involved in spermatogenesis.

7918:sspo
gene id: 7918:sspo
uniprot id: W5MQB1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

7918:coq9
gene id: 7918:coq9
uniprot id: W5M5X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

7918:laptm5
gene id: 7918:laptm5
uniprot id: W5MCU0
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

7918:LOC102687583
gene id: 7918:LOC102687583
uniprot id: W5M2M9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:rbp4
gene id: 7918:rbp4
uniprot id: W5MF78
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

7918:cryaa
gene id: 7918:cryaa
uniprot id: W5LZ71
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

7918:LOC102686545
gene id: 7918:LOC102686545
uniprot id: W5MUX9
names: Similarity
messages: Belongs to the AAA ATPase family.

7918:maml1
gene id: 7918:maml1
uniprot id: W5N088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

7918:LOC102685925
gene id: 7918:LOC102685925
uniprot id: W5N7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Photoreceptor outer segment membrane

7918:smarcd3
gene id: 7918:smarcd3
uniprot id: W5MRQ1
uniprot id: W5MRR5
names: Similarity
messages: Belongs to the SMARCD family.

7918:esyt2
gene id: 7918:esyt2
uniprot id: W5N3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:rnf7
gene id: 7918:rnf7
uniprot id: W5MN34
names: Similarity
messages: Belongs to the RING-box family.

7918:snx20
gene id: 7918:snx20
uniprot id: W5MKG1
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

7918:clg12h2orf76
gene id: 7918:clg12h2orf76
uniprot id: W5M634
names: Similarity
messages: Belongs to the UPF0538 family.

7918:dpyd
gene id: 7918:dpyd
uniprot id: W5MNR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

7918:dhx29
gene id: 7918:dhx29
uniprot id: W5MVP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

7918:tes
gene id: 7918:tes
uniprot id: W5NF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

7918:plpp4
gene id: 7918:plpp4
uniprot id: W5MQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

7918:nxph1
gene id: 7918:nxph1
uniprot id: W5MZ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

7918:coro2a
gene id: 7918:coro2a
uniprot id: W5N242
names: Similarity
messages: Belongs to the WD repeat coronin family.

7918:men1
gene id: 7918:men1
uniprot id: W5M217
names: Subcellular Location Annotation
messages: Nucleus

7918:onecut2
gene id: 7918:onecut2
uniprot id: W5M7F0
uniprot id: W5M7G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

7918:LOC102696348
gene id: 7918:LOC102696348
uniprot id: W5MBC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

7918:mmd2
gene id: 7918:mmd2
uniprot id: W5MAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

7918:epha2
gene id: 7918:epha2
uniprot id: W5MMU5
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102687514
gene id: 7918:LOC102687514
uniprot id: W5M4F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted
messages: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.

7918:LOC102689122
gene id: 7918:LOC102689122
uniprot id: W5NNQ6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:LOC102697482
gene id: 7918:LOC102697482
uniprot id: W5N434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

7918:LOC102682847
gene id: 7918:LOC102682847
uniprot id: W5NHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

7918:sar1a
gene id: 7918:sar1a
uniprot id: W5MD13
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

7918:soga3
gene id: 7918:soga3
uniprot id: W5NKB8
names: Similarity
messages: Belongs to the SOGA family.

7918:urm1
gene id: 7918:urm1
uniprot id: W5M4E8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Cytoplasm

7918:LOC102689289
gene id: 7918:LOC102689289
uniprot id: W5MEI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

7918:vps26b
gene id: 7918:vps26b
uniprot id: W5MCB6
names: Similarity
messages: Belongs to the VPS26 family.

7918:gda
gene id: 7918:gda
uniprot id: W5MTJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

7918:aasdh
gene id: 7918:aasdh
uniprot id: W5N9G5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

7918:LOC102699158
gene id: 7918:LOC102699158
uniprot id: W5MVV5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

7918:ap3s1
gene id: 7918:ap3s1
uniprot id: W5MR52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

7918:nos2
gene id: 7918:nos2
uniprot id: W5MEJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

7918:ak8
gene id: 7918:ak8
uniprot id: W5MEM4
names: Similarity
messages: Belongs to the adenylate kinase family.

7918:trpm6
gene id: 7918:trpm6
uniprot id: W5MU31
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

7918:gcgr
gene id: 7918:gcgr
uniprot id: W5N950
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:LOC102689914
gene id: 7918:LOC102689914
uniprot id: W5NLY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

7918:foxp4
gene id: 7918:foxp4
uniprot id: W5N2W0
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102692230
gene id: 7918:LOC102692230
uniprot id: W5MLY7
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

7918:tmem168
gene id: 7918:tmem168
uniprot id: W5NG57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane
messages: Nucleus membrane

7918:adcy2
gene id: 7918:adcy2
uniprot id: W5LX23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

7918:il2rb
gene id: 7918:il2rb
uniprot id: W5MZA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

7918:ormdl1
gene id: 7918:ormdl1
uniprot id: W5MQP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

7918:myo19
gene id: 7918:myo19
uniprot id: W5M5S0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

7918:dact3
gene id: 7918:dact3
uniprot id: W5NB62
names: Similarity
messages: Belongs to the dapper family.

7918:tgfbr2
gene id: 7918:tgfbr2
uniprot id: W5M2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

7918:bcl2
gene id: 7918:bcl2
uniprot id: W5N4F7
names: Similarity
messages: Belongs to the Bcl-2 family.

7918:wbscr17
gene id: 7918:wbscr17
uniprot id: W5M8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:fam227a
gene id: 7918:fam227a
uniprot id: W5MET6
names: Similarity
messages: Belongs to the FAM227 family.

7918:snrpd2
gene id: 7918:snrpd2
uniprot id: W5NC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

7918:uchl3
gene id: 7918:uchl3
uniprot id: W5N056
names: Similarity
messages: Belongs to the peptidase C12 family.

7918:lsm8
gene id: 7918:lsm8
uniprot id: W5NEX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

7918:zer1
gene id: 7918:zer1
uniprot id: W5MF87
names: Similarity
messages: Belongs to the zyg-11 family.

7918:suz12
gene id: 7918:suz12
uniprot id: W5N8Q0
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

7918:LOC102697740
gene id: 7918:LOC102697740
uniprot id: W5LXX9
names: Subcellular Location Annotation
messages: Membrane

7918:uba6
gene id: 7918:uba6
uniprot id: W5N435
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

7918:prim1
gene id: 7918:prim1
uniprot id: W5MKI7
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

7918:chl1
gene id: 7918:chl1
uniprot id: W5MUL9
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

7918:LOC102690794
gene id: 7918:LOC102690794
uniprot id: W5MA43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

7918:gtpbp10
gene id: 7918:gtpbp10
uniprot id: W5MW84
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

7918:fam83c
gene id: 7918:fam83c
uniprot id: W5MLW7
names: Similarity
messages: Belongs to the FAM83 family.

7918:LOC102685080
gene id: 7918:LOC102685080
uniprot id: W5MDR8
names: Similarity
messages: Belongs to the SPIN/STSY family.

7918:fam8a1
gene id: 7918:fam8a1
uniprot id: W5M4U6
names: Subcellular Location Annotation
messages: Membrane

7918:gal
gene id: 7918:gal
uniprot id: W5M3G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

7918:jagn1
gene id: 7918:jagn1
uniprot id: W5MT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:slc7a11
gene id: 7918:slc7a11
uniprot id: W5MX66
names: Subcellular Location Annotation
messages: Membrane

7918:scg5
gene id: 7918:scg5
uniprot id: W5N4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

7918:evc2
gene id: 7918:evc2
uniprot id: W5MV80
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

7918:lrp5
gene id: 7918:lrp5
uniprot id: W5M3V3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:aldh9a1
gene id: 7918:aldh9a1
uniprot id: W5MFZ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

7918:LOC102689929
gene id: 7918:LOC102689929
uniprot id: W5M3D7
uniprot id: W5M3F3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

7918:LOC102694917
gene id: 7918:LOC102694917
uniprot id: W5NEH2
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

7918:sdc4
gene id: 7918:sdc4
uniprot id: W5MLP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

7918:LOC102689931
gene id: 7918:LOC102689931
uniprot id: W5NE31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:nr0b2
gene id: 7918:nr0b2
uniprot id: W5M8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

7918:fabp2
gene id: 7918:fabp2
uniprot id: W5N4A7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

7918:LOC102682727
gene id: 7918:LOC102682727
uniprot id: W5LXR6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

7918:mitf
gene id: 7918:mitf
uniprot id: W5MV93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

7918:atrn
gene id: 7918:atrn
uniprot id: W5LY60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:sgms2
gene id: 7918:sgms2
uniprot id: W5N4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

7918:ppp6r2
gene id: 7918:ppp6r2
uniprot id: W5NJF8
uniprot id: W5NJG1
names: Similarity
messages: Belongs to the SAPS family.

7918:dusp1
gene id: 7918:dusp1
uniprot id: W5N2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

7918:kiaa1161
gene id: 7918:kiaa1161
uniprot id: W5MBG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

7918:gata6
gene id: 7918:gata6
uniprot id: W5M0Z4
names: Subcellular Location Annotation
messages: Nucleus

7918:stk32a
gene id: 7918:stk32a
uniprot id: W5MXW6
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:serp2
gene id: 7918:serp2
uniprot id: W5MEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

7918:stx7
gene id: 7918:stx7
uniprot id: W5NK85
names: Similarity
messages: Belongs to the syntaxin family.

7918:gper1
gene id: 7918:gper1
uniprot id: W5NNJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:LOC102686778
gene id: 7918:LOC102686778
uniprot id: W5N872
names: Similarity
messages: Belongs to the SUI1 family.

7918:cdc42se2
gene id: 7918:cdc42se2
uniprot id: W5MNR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

7918:tmem163
gene id: 7918:tmem163
uniprot id: W5M139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

7918:rpl13a
gene id: 7918:rpl13a
uniprot id: W5MA34
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

7918:LOC102697258
gene id: 7918:LOC102697258
uniprot id: W5MLA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

7918:fam69b
gene id: 7918:fam69b
uniprot id: W5M7N1
names: Similarity
messages: Belongs to the DIPK family.

7918:LOC102692353
gene id: 7918:LOC102692353
uniprot id: W5MZF9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102694268
gene id: 7918:LOC102694268
uniprot id: W5NL08
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:nr2e1
gene id: 7918:nr2e1
uniprot id: W5NIP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:cldn14
gene id: 7918:cldn14
uniprot id: W5NLL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:fgfr3
gene id: 7918:fgfr3
uniprot id: W5MJI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:serinc5
gene id: 7918:serinc5
uniprot id: W5MG23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

7918:ndfip1
gene id: 7918:ndfip1
uniprot id: W5MX23
names: Subcellular Location Annotation
messages: Membrane

7918:vps35
gene id: 7918:vps35
uniprot id: W5ME32
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

7918:il17c
gene id: 7918:il17c
uniprot id: W5M390
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

7918:LOC102692498
gene id: 7918:LOC102692498
uniprot id: W5NMT0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:gabrd
gene id: 7918:gabrd
uniprot id: W5MG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:hnrnpr
gene id: 7918:hnrnpr
uniprot id: W5MA51
names: Subcellular Location Annotation
messages: Cytoplasm

7918:rheb
gene id: 7918:rheb
uniprot id: W5MV23
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:dhodh
gene id: 7918:dhodh
uniprot id: W5MAC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

7918:sema4b
gene id: 7918:sema4b
uniprot id: W5NAJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:kdm1b
gene id: 7918:kdm1b
uniprot id: W5MFG8
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

7918:cd74
gene id: 7918:cd74
uniprot id: W5MYP5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:abat
gene id: 7918:abat
uniprot id: W5MHX2
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

7918:iars
gene id: 7918:iars
uniprot id: W5N911
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

7918:LOC102692811
gene id: 7918:LOC102692811
uniprot id: W5NNY4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:pi4k2a
gene id: 7918:pi4k2a
uniprot id: W5M7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

7918:eva1c
gene id: 7918:eva1c
uniprot id: W5MS77
names: Similarity
messages: Belongs to the EVA1 family.

7918:slc18a1
gene id: 7918:slc18a1
uniprot id: W5NDB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

7918:LOC102692803
gene id: 7918:LOC102692803
uniprot id: W5M4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

7918:penk
gene id: 7918:penk
uniprot id: W5MDH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

7918:erc1
gene id: 7918:erc1
uniprot id: W5NIW0
names: Subcellular Location Annotation
messages: Cytoplasm

7918:slc1a5
gene id: 7918:slc1a5
uniprot id: W5NCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

7918:rhbdl1
gene id: 7918:rhbdl1
uniprot id: W5M6W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

7918:atp6v0d1
gene id: 7918:atp6v0d1
uniprot id: W5MNF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

7918:slc12a1
gene id: 7918:slc12a1
uniprot id: W5N6P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

7918:taf11
gene id: 7918:taf11
uniprot id: W5MV46
names: Similarity
messages: Belongs to the TAF11 family.

7918:jmjd1c
gene id: 7918:jmjd1c
uniprot id: W5MIW4
names: Subcellular Location Annotation
messages: Nucleus

7918:gprin1
gene id: 7918:gprin1
uniprot id: W5NP55
names: Function
messages: May be involved in neurite outgrowth.

7918:foxd3
gene id: 7918:foxd3
uniprot id: W5NMI5
names: Subcellular Location Annotation
messages: Nucleus

7918:sla
gene id: 7918:sla
uniprot id: W5MKF7
names: Subcellular Location Annotation
messages: Cytoplasm

7918:ndc1
gene id: 7918:ndc1
uniprot id: W5M5I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

7918:id4
gene id: 7918:id4
uniprot id: W5MTS0
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102683566
gene id: 7918:LOC102683566
uniprot id: W5LY78
names: Similarity
messages: Belongs to the CD225/Dispanin family.

7918:rab39a
gene id: 7918:rab39a
uniprot id: W5MIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

7918:shcbp1
gene id: 7918:shcbp1
uniprot id: W5ME92
names: Subcellular Location Annotation
messages: spindle

7918:clg4h4orf47
gene id: 7918:clg4h4orf47
uniprot id: W5N8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP96 family.
messages: centrosome

7918:tshz1
gene id: 7918:tshz1
uniprot id: W5M8R8
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

7918:strn4
gene id: 7918:strn4
uniprot id: W5NCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

7918:avl9
gene id: 7918:avl9
uniprot id: W5N5G5
names: Subcellular Location Annotation
messages: Recycling endosome

7918:tctex1d1
gene id: 7918:tctex1d1
uniprot id: W5MJ79
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

7918:fut10
gene id: 7918:fut10
uniprot id: W5MY23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

7918:mthfd1l
gene id: 7918:mthfd1l
uniprot id: W5NHK8
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

7918:pou3f2
gene id: 7918:pou3f2
uniprot id: W5NMW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

7918:tnpo1
gene id: 7918:tnpo1
uniprot id: W5MZ22
names: Subcellular Location Annotation
messages: Cytoplasm

7918:slc25a43
gene id: 7918:slc25a43
uniprot id: W5NDN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:LOC102695921
gene id: 7918:LOC102695921
uniprot id: W5MYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

7918:esrrb
gene id: 7918:esrrb
uniprot id: W5MXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

7918:arap3
gene id: 7918:arap3
uniprot id: W5N0L7
names: Subcellular Location Annotation
messages: Cytoplasm

7918:traf5
gene id: 7918:traf5
uniprot id: W5NEW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

7918:rbm47
gene id: 7918:rbm47
uniprot id: W5N5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Cytoplasm
messages: Nucleus

7918:LOC102692534
gene id: 7918:LOC102692534
uniprot id: W5NN15
names: Subcellular Location Annotation
messages: Membrane

7918:gab3
gene id: 7918:gab3
uniprot id: W5NBG4
names: Similarity
messages: Belongs to the GAB family.

7918:dmrt3
gene id: 7918:dmrt3
uniprot id: W5N0E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

7918:tenm1
gene id: 7918:tenm1
uniprot id: W5NBD5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:usp21
gene id: 7918:usp21
uniprot id: W5M0U4
names: Similarity
messages: Belongs to the peptidase C19 family.

7918:actl6b
gene id: 7918:actl6b
uniprot id: W5N7P8
names: Similarity
messages: Belongs to the actin family.

7918:pamr1
gene id: 7918:pamr1
uniprot id: W5LZR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:dlat
gene id: 7918:dlat
uniprot id: W5M021
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

7918:LOC102684353
gene id: 7918:LOC102684353
uniprot id: W5M1K1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:rbbp4
gene id: 7918:rbbp4
uniprot id: W5M2I1
names: Subcellular Location Annotation
messages: Nucleus

7918:rhbdd1
gene id: 7918:rhbdd1
uniprot id: W5MTA9
names: Subcellular Location Annotation
messages: Membrane

7918:tmem9b
gene id: 7918:tmem9b
uniprot id: W5M6S8
names: Similarity
messages: Belongs to the TMEM9 family.

7918:camsap2
gene id: 7918:camsap2
uniprot id: W5MLX6
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

7918:ggact
gene id: 7918:ggact
uniprot id: W5M567
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine.

7918:tubb1
gene id: 7918:tubb1
uniprot id: W5MGU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

7918:gdpd2
gene id: 7918:gdpd2
uniprot id: W5NDJ8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

7918:vill
gene id: 7918:vill
uniprot id: W5MU23
names: Similarity
messages: Belongs to the villin/gelsolin family.

7918:LOC102697492
gene id: 7918:LOC102697492
uniprot id: W5M7R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

7918:tie1
gene id: 7918:tie1
uniprot id: W5MH08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:cpne8
gene id: 7918:cpne8
uniprot id: W5NGQ9
names: Similarity
messages: Belongs to the copine family.

7918:LOC102695740
gene id: 7918:LOC102695740
uniprot id: W5NMJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

7918:tgfbr1
gene id: 7918:tgfbr1
uniprot id: W5MXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

7918:LOC102698461
gene id: 7918:LOC102698461
uniprot id: W5NDI5
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

7918:nfkb1
gene id: 7918:nfkb1
uniprot id: W5N2L1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:slc29a4
gene id: 7918:slc29a4
uniprot id: W5MBI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

7918:LOC102693975
gene id: 7918:LOC102693975
uniprot id: W5MFU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

7918:tgfa
gene id: 7918:tgfa
uniprot id: W5NF74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:vrtn
gene id: 7918:vrtn
uniprot id: W5NMF0
names: Similarity
messages: Belongs to the vertnin family.

7918:tmem177
gene id: 7918:tmem177
uniprot id: W5NMS0
names: Function
names: Similarity
messages: Belongs to the TMEM177 family.
messages: Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.

7918:tjp3
gene id: 7918:tjp3
uniprot id: W5MAP2
names: Similarity
messages: Belongs to the MAGUK family.

7918:clrn2
gene id: 7918:clrn2
uniprot id: W5M5X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

7918:rbm22
gene id: 7918:rbm22
uniprot id: W5MYL8
names: Similarity
messages: Belongs to the SLT11 family.

7918:lars2
gene id: 7918:lars2
uniprot id: W5M1Y4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

7918:sptbn1
gene id: 7918:sptbn1
uniprot id: W5NER6
names: Similarity
messages: Belongs to the spectrin family.

7918:slc7a14
gene id: 7918:slc7a14
uniprot id: W5MKB5
names: Subcellular Location Annotation
messages: Membrane

7918:ythdf1
gene id: 7918:ythdf1
uniprot id: W5MCD5
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

7918:gcdh
gene id: 7918:gcdh
uniprot id: W5MP40
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

7918:senp2
gene id: 7918:senp2
uniprot id: W5MTF6
names: Similarity
messages: Belongs to the peptidase C48 family.

7918:LOC107076888
gene id: 7918:LOC107076888
uniprot id: W5N657
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

7918:ache
gene id: 7918:ache
uniprot id: W5N9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

7918:hyls1
gene id: 7918:hyls1
uniprot id: W5NIT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

7918:psma8
gene id: 7918:psma8
uniprot id: W5MH18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

7918:exoc5
gene id: 7918:exoc5
uniprot id: W5MZC2
names: Similarity
messages: Belongs to the SEC10 family.

7918:LOC102696071
gene id: 7918:LOC102696071
uniprot id: W5MT88
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:mybl1
gene id: 7918:mybl1
uniprot id: W5MB91
names: Subcellular Location Annotation
messages: Nucleus

7918:gdf10
gene id: 7918:gdf10
uniprot id: W5M8I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

7918:pon2
gene id: 7918:pon2
uniprot id: W5MYG9
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

7918:ube3d
gene id: 7918:ube3d
uniprot id: W5NKD5
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

7918:sptbn4
gene id: 7918:sptbn4
uniprot id: W5NBC1
names: Similarity
messages: Belongs to the spectrin family.

7918:LOC102696479
gene id: 7918:LOC102696479
uniprot id: W5MHU8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102689101
gene id: 7918:LOC102689101
uniprot id: W5MG89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:LOC102682268
gene id: 7918:LOC102682268
uniprot id: W5MHK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

7918:nhs
gene id: 7918:nhs
uniprot id: W5MLK0
names: Similarity
messages: Belongs to the NHS family.

7918:tiparp
gene id: 7918:tiparp
uniprot id: W5M679
names: Similarity
messages: Belongs to the ARTD/PARP family.

7918:elovl6
gene id: 7918:elovl6
uniprot id: W5N1F0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

7918:mvk
gene id: 7918:mvk
uniprot id: W5M9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

7918:trnau1ap
gene id: 7918:trnau1ap
uniprot id: W5M8X8
names: Similarity
messages: Belongs to the RRM TRSPAP family.

7918:gsx2
gene id: 7918:gsx2
uniprot id: W5N9W7
names: Subcellular Location Annotation
messages: Nucleus

7918:KEF94 p09
gene id: 7918:KEF94_p09
uniprot id: Q8HQM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrion membrane

7918:LOC102697185
gene id: 7918:LOC102697185
uniprot id: W5LZX5
names: Similarity
messages: Belongs to the TGF-beta family.

7918:thg1l
gene id: 7918:thg1l
uniprot id: W5MSC9
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

7918:rrn3
gene id: 7918:rrn3
uniprot id: W5MKS5
names: Similarity
messages: Belongs to the RRN3 family.

7918:eif4a1
gene id: 7918:eif4a1
uniprot id: W5NAZ5
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

7918:timm13
gene id: 7918:timm13
uniprot id: W5M9S9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

7918:dbx1
gene id: 7918:dbx1
uniprot id: W5MBW6
names: Subcellular Location Annotation
messages: Nucleus

7918:ube2h
gene id: 7918:ube2h
uniprot id: W5NG94
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:LOC102686680
gene id: 7918:LOC102686680
uniprot id: W5N587
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

7918:smpdl3b
gene id: 7918:smpdl3b
uniprot id: W5M6L3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

7918:LOC102696570
gene id: 7918:LOC102696570
uniprot id: W5MPN8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:ppdpf
gene id: 7918:ppdpf
uniprot id: W5MCX1
names: Similarity
messages: Belongs to the PPDPF family.

7918:rad18
gene id: 7918:rad18
uniprot id: W5MXA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

7918:trappc13
gene id: 7918:trappc13
uniprot id: W5MX54
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

7918:nrtn
gene id: 7918:nrtn
uniprot id: W5M5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

7918:ppp2r5e
gene id: 7918:ppp2r5e
uniprot id: W5MVW0
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

7918:adcy3
gene id: 7918:adcy3
uniprot id: W5NG54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

7918:parg
gene id: 7918:parg
uniprot id: W5MET1
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

7918:tmtc3
gene id: 7918:tmtc3
uniprot id: W5NHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

7918:upf3b
gene id: 7918:upf3b
uniprot id: W5NDP1
names: Similarity
messages: Belongs to the RENT3 family.

7918:LOC102687346
gene id: 7918:LOC102687346
uniprot id: W5NAX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:uncx
gene id: 7918:uncx
uniprot id: W5LZ31
names: Subcellular Location Annotation
messages: Nucleus

7918:rnps1
gene id: 7918:rnps1
uniprot id: W5M0W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

7918:utp23
gene id: 7918:utp23
uniprot id: W5M674
names: Subcellular Location Annotation
messages: nucleolus

7918:ube2b
gene id: 7918:ube2b
uniprot id: W5MVV1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:ccdc34
gene id: 7918:ccdc34
uniprot id: W5MHB0
names: Subcellular Location Annotation
messages: flagellum

7918:pitx2
gene id: 7918:pitx2
uniprot id: W5N1B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

7918:kif6
gene id: 7918:kif6
uniprot id: W5NKR8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:casp8
gene id: 7918:casp8
uniprot id: W5MXS7
names: Similarity
messages: Belongs to the peptidase C14A family.

7918:lvrn
gene id: 7918:lvrn
uniprot id: W5MR35
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

7918:LOC102682437
gene id: 7918:LOC102682437
uniprot id: W5NE12
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

7918:prkx
gene id: 7918:prkx
uniprot id: W5MVS4
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:krr1
gene id: 7918:krr1
uniprot id: W5NHE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

7918:amdhd1
gene id: 7918:amdhd1
uniprot id: W5NFG5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

7918:treh
gene id: 7918:treh
uniprot id: W5LXH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

7918:LOC102685475
gene id: 7918:LOC102685475
uniprot id: W5MB97
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102686397
gene id: 7918:LOC102686397
uniprot id: W5MJ05
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).
messages: cytosol

7918:LOC102682666
gene id: 7918:LOC102682666
uniprot id: W5MLV5
names: Similarity
messages: Belongs to the CBP3 family.

7918:pcnt
gene id: 7918:pcnt
uniprot id: W5MTC6
names: Subcellular Location Annotation
messages: centrosome

7918:dyrk3
gene id: 7918:dyrk3
uniprot id: W5N345
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

7918:ppil4
gene id: 7918:ppil4
uniprot id: W5NK57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

7918:hoxd10
gene id: 7918:hoxd10
uniprot id: W5MJQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

7918:yeats4
gene id: 7918:yeats4
uniprot id: W5NH50
names: Subcellular Location Annotation
messages: Nucleus

7918:gltscr2
gene id: 7918:gltscr2
uniprot id: W5NA07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

7918:sema3e
gene id: 7918:sema3e
uniprot id: W5NHY8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ptk6
gene id: 7918:ptk6
uniprot id: W5MCZ0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:LOC102692695
gene id: 7918:LOC102692695
uniprot id: W5NP63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

7918:tmem178a
gene id: 7918:tmem178a
uniprot id: W5NFI3
names: Similarity
messages: Belongs to the TMEM178 family.

7918:sstr1
gene id: 7918:sstr1
uniprot id: W5NME7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:fam216a
gene id: 7918:fam216a
uniprot id: W5MK77
names: Similarity
messages: Belongs to the FAM216 family.

7918:b3galt2
gene id: 7918:b3galt2
uniprot id: W5NMI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:LOC102693325
gene id: 7918:LOC102693325
uniprot id: W5LXJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

7918:ccm2
gene id: 7918:ccm2
uniprot id: W5NFS4
names: Similarity
messages: Belongs to the CCM2 family.

7918:sike1
gene id: 7918:sike1
uniprot id: W5MWJ9
names: Similarity
messages: Belongs to the SIKE family.

7918:elac1
gene id: 7918:elac1
uniprot id: W5N5C9
names: Subunit
messages: Homodimer.

7918:sh3bgrl2
gene id: 7918:sh3bgrl2
uniprot id: W5NHB4
names: Similarity
messages: Belongs to the SH3BGR family.

7918:pth2r
gene id: 7918:pth2r
uniprot id: W5M1B0
names: Subcellular Location Annotation
messages: Membrane

7918:tmem47
gene id: 7918:tmem47
uniprot id: W5MVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

7918:atad2
gene id: 7918:atad2
uniprot id: W5MSI3
names: Similarity
messages: Belongs to the AAA ATPase family.

7918:mapre1
gene id: 7918:mapre1
uniprot id: W5MEI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

7918:hspa4l
gene id: 7918:hspa4l
uniprot id: W5MXV5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

7918:rras2
gene id: 7918:rras2
uniprot id: W5M5Z3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:LOC102694648
gene id: 7918:LOC102694648
uniprot id: W5MNP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:clg5h10orf35
gene id: 7918:clg5h10orf35
uniprot id: W5N0L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

7918:kmt5a
gene id: 7918:kmt5a
uniprot id: W5MEX4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

7918:clg2h5orf30
gene id: 7918:clg2h5orf30
uniprot id: W5NLY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

7918:LOC102683822
gene id: 7918:LOC102683822
uniprot id: W5N173
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

7918:LOC102697237
gene id: 7918:LOC102697237
uniprot id: W5MMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

7918:azin1
gene id: 7918:azin1
uniprot id: W5MUT1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

7918:tmem39b
gene id: 7918:tmem39b
uniprot id: W5M2T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

7918:htra3
gene id: 7918:htra3
uniprot id: W5MW45
names: Similarity
messages: Belongs to the peptidase S1C family.

7918:kcnab1
gene id: 7918:kcnab1
uniprot id: W5M646
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

7918:unc119
gene id: 7918:unc119
uniprot id: W5ME35
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

7918:sec23b
gene id: 7918:sec23b
uniprot id: W5NGZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

7918:zdhhc4
gene id: 7918:zdhhc4
uniprot id: W5MDA0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

7918:LOC102698937
gene id: 7918:LOC102698937
uniprot id: W5NBE1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

7918:chrna4
gene id: 7918:chrna4
uniprot id: W5M0H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:tnfsf13b
gene id: 7918:tnfsf13b
uniprot id: W5MR41
names: Similarity
messages: Belongs to the tumor necrosis factor family.

7918:cenpc
gene id: 7918:cenpc
uniprot id: W5M491
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

7918:alx1
gene id: 7918:alx1
uniprot id: W5NHR9
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102698141
gene id: 7918:LOC102698141
uniprot id: W5N263
names: Similarity
messages: Belongs to the lst-2 family.

7918:cdc5l
gene id: 7918:cdc5l
uniprot id: W5NFQ7
names: Similarity
messages: Belongs to the CEF1 family.

7918:abcb5
gene id: 7918:abcb5
uniprot id: W5N0D2
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102688792
gene id: 7918:LOC102688792
uniprot id: W5MIK5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

7918:mpg
gene id: 7918:mpg
uniprot id: W5MLU0
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

7918:LOC102690357
gene id: 7918:LOC102690357
uniprot id: W5M663
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

7918:cplx3
gene id: 7918:cplx3
uniprot id: W5NBI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

7918:mttp
gene id: 7918:mttp
uniprot id: W5N3E0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:coq5
gene id: 7918:coq5
uniprot id: W5MQB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

7918:LOC102687587
gene id: 7918:LOC102687587
uniprot id: W5NHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

7918:cmpk1
gene id: 7918:cmpk1
uniprot id: W5MVR3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

7918:usp34
gene id: 7918:usp34
uniprot id: W5NGU3
names: Similarity
messages: Belongs to the peptidase C19 family.

7918:sfxn1
gene id: 7918:sfxn1
uniprot id: W5MY15
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

7918:LOC102692261
gene id: 7918:LOC102692261
uniprot id: W5MI70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

7918:akirin1
gene id: 7918:akirin1
uniprot id: W5MEU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

7918:alad
gene id: 7918:alad
uniprot id: W5LX75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

7918:LOC102690851
gene id: 7918:LOC102690851
uniprot id: W5NE97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:LOC102693095
gene id: 7918:LOC102693095
uniprot id: W5NJM3
names: Similarity
messages: Belongs to the ARTD/PARP family.

7918:arf6
gene id: 7918:arf6
uniprot id: W5NMF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

7918:mpl
gene id: 7918:mpl
uniprot id: W5MGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane

7918:dbr1
gene id: 7918:dbr1
uniprot id: W5M9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

7918:slc25a21
gene id: 7918:slc25a21
uniprot id: W5N9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:ppp2r5d
gene id: 7918:ppp2r5d
uniprot id: W5NJ70
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

7918:KEF94 p06
gene id: 7918:KEF94_p06
uniprot id: Q8HQM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

7918:cpo
gene id: 7918:cpo
uniprot id: W5MZ02
names: Similarity
messages: Belongs to the peptidase M14 family.

7918:ccz1
gene id: 7918:ccz1
uniprot id: W5MPS9
names: Similarity
messages: Belongs to the CCZ1 family.

7918:cep76
gene id: 7918:cep76
uniprot id: W5MTR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: centriole

7918:fgf7
gene id: 7918:fgf7
uniprot id: W5N6F5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

7918:LOC102690218
gene id: 7918:LOC102690218
uniprot id: W5MTD2
names: Similarity
messages: Belongs to the AccD/PCCB family.

7918:mcm10
gene id: 7918:mcm10
uniprot id: W5NFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

7918:apob
gene id: 7918:apob
uniprot id: W5NKW1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102685895
gene id: 7918:LOC102685895
uniprot id: W5MMB7
names: Similarity
messages: Belongs to the Bcl-2 family.

7918:sox14
gene id: 7918:sox14
uniprot id: W5NLJ8
names: Subcellular Location Annotation
messages: Nucleus

7918:mppe1
gene id: 7918:mppe1
uniprot id: W5M2B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

7918:rnf121
gene id: 7918:rnf121
uniprot id: W5MMH4
names: Subcellular Location Annotation
messages: Membrane

7918:heg1
gene id: 7918:heg1
uniprot id: W5M4A8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:tnfaip6
gene id: 7918:tnfaip6
uniprot id: W5M458
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:glipr1
gene id: 7918:glipr1
uniprot id: W5NHE5
names: Similarity
messages: Belongs to the CRISP family.

7918:scml2
gene id: 7918:scml2
uniprot id: W5MLE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

7918:chst12
gene id: 7918:chst12
uniprot id: W5NNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:zfx
gene id: 7918:zfx
uniprot id: W5M6F9
names: Subcellular Location Annotation
messages: Nucleus

7918:ube2f
gene id: 7918:ube2f
uniprot id: W5MA05
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:pex2
gene id: 7918:pex2
uniprot id: W5N7K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

7918:cdh2
gene id: 7918:cdh2
uniprot id: W5MGP8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

7918:oat
gene id: 7918:oat
uniprot id: W5MN94
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

7918:LOC107075817
gene id: 7918:LOC107075817
uniprot id: W5MDF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

7918:abca3
gene id: 7918:abca3
uniprot id: W5M3R8
names: Subcellular Location Annotation
messages: Membrane

7918:brs3
gene id: 7918:brs3
uniprot id: W5ND94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:slc41a1
gene id: 7918:slc41a1
uniprot id: W5N1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

7918:camk1d
gene id: 7918:camk1d
uniprot id: W5NFD6
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:optn
gene id: 7918:optn
uniprot id: W5NFE0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

7918:smad2
gene id: 7918:smad2
uniprot id: W5N3S0
uniprot id: W5N3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

7918:foxo6
gene id: 7918:foxo6
uniprot id: W5M5A9
names: Subcellular Location Annotation
messages: Nucleus

7918:atp8a1
gene id: 7918:atp8a1
uniprot id: W5N3W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

7918:pex16
gene id: 7918:pex16
uniprot id: W5MDN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

7918:slc6a7
gene id: 7918:slc6a7
uniprot id: W5MZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

7918:LOC102684075
gene id: 7918:LOC102684075
uniprot id: W5MKN8
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:LOC102688670
gene id: 7918:LOC102688670
uniprot id: W5M6J1
names: Subcellular Location Annotation
messages: Membrane

7918:ccne2
gene id: 7918:ccne2
uniprot id: W5MH58
names: Similarity
messages: Belongs to the cyclin family.

7918:atic
gene id: 7918:atic
uniprot id: W5MV24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PurH family.
messages: cytosol

7918:dgkh
gene id: 7918:dgkh
uniprot id: W5MF59
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

7918:perp
gene id: 7918:perp
uniprot id: W5NEC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

7918:clcn3
gene id: 7918:clcn3
uniprot id: W5N668
uniprot id: W5N670
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

7918:LOC107078406
gene id: 7918:LOC107078406
uniprot id: W5MNY9
names: Similarity
messages: Belongs to the DNase II family.

7918:arsa
gene id: 7918:arsa
uniprot id: W5NJA8
names: Similarity
messages: Belongs to the sulfatase family.

7918:LOC102684062
gene id: 7918:LOC102684062
uniprot id: W5NP13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:LOC102689238
gene id: 7918:LOC102689238
uniprot id: W5NE46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

7918:atp6v1d
gene id: 7918:atp6v1d
uniprot id: W5N9Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

7918:atg16l2
gene id: 7918:atg16l2
uniprot id: W5M407
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

7918:gphb5
gene id: 7918:gphb5
uniprot id: W5MVU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

7918:kiaa1191
gene id: 7918:kiaa1191
uniprot id: W5MYB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

7918:dock10
gene id: 7918:dock10
uniprot id: W5M8G1
names: Similarity
messages: Belongs to the DOCK family.

7918:pigk
gene id: 7918:pigk
uniprot id: W5M7B4
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.

7918:kif19
gene id: 7918:kif19
uniprot id: W5N5D7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:rnaseh2b
gene id: 7918:rnaseh2b
uniprot id: W5MSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

7918:vps13d
gene id: 7918:vps13d
uniprot id: W5M672
names: Similarity
messages: Belongs to the VPS13 family.

7918:tcf25
gene id: 7918:tcf25
uniprot id: W5LZ49
names: Similarity
messages: Belongs to the TCF25 family.

7918:nucb2
gene id: 7918:nucb2
uniprot id: W5M4Z7
names: Similarity
messages: Belongs to the nucleobindin family.

7918:tlx1
gene id: 7918:tlx1
uniprot id: W5N0Z3
names: Subcellular Location Annotation
messages: Nucleus

7918:aif1l
gene id: 7918:aif1l
uniprot id: W5MH00
names: Subcellular Location Annotation
messages: ruffle membrane

7918:exoc4
gene id: 7918:exoc4
uniprot id: W5NF36
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

7918:rps12
gene id: 7918:rps12
uniprot id: W5NHB0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

7918:LOC107078653
gene id: 7918:LOC107078653
uniprot id: W5MNV3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ciapin1
gene id: 7918:ciapin1
uniprot id: W5M5U1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

7918:hdac1
gene id: 7918:hdac1
uniprot id: W5M3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins.
messages: Nucleus

7918:LOC102697213
gene id: 7918:LOC102697213
uniprot id: W5M221
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

7918:hmga1
gene id: 7918:hmga1
uniprot id: W5MUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

7918:nkd2
gene id: 7918:nkd2
uniprot id: W5MNC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

7918:LOC107076798
gene id: 7918:LOC107076798
uniprot id: W5NN72
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:foxk2
gene id: 7918:foxk2
uniprot id: W5N303
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102695888
gene id: 7918:LOC102695888
uniprot id: W5LZR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

7918:srf
gene id: 7918:srf
uniprot id: W5NG09
names: Subcellular Location Annotation
messages: Nucleus

7918:vsx1
gene id: 7918:vsx1
uniprot id: W5NJE3
names: Subcellular Location Annotation
messages: Nucleus

7918:dok2
gene id: 7918:dok2
uniprot id: W5NCI8
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

7918:LOC102682536
gene id: 7918:LOC102682536
uniprot id: W5M141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

7918:polr2i
gene id: 7918:polr2i
uniprot id: W5NC88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

7918:homer1
gene id: 7918:homer1
uniprot id: W5MFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

7918:LOC102698400
gene id: 7918:LOC102698400
uniprot id: W5MSB7
names: Subcellular Location Annotation
messages: Membrane

7918:sft2d1
gene id: 7918:sft2d1
uniprot id: W5NIF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

7918:higd2a
gene id: 7918:higd2a
uniprot id: W5N1Y1
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

7918:LOC102686996
gene id: 7918:LOC102686996
uniprot id: W5NEQ6
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

7918:stim1
gene id: 7918:stim1
uniprot id: W5MMU3
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102697762
gene id: 7918:LOC102697762
uniprot id: W5MTW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

7918:kcnd1
gene id: 7918:kcnd1
uniprot id: W5NB68
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

7918:LOC102697066
gene id: 7918:LOC102697066
uniprot id: W5MI61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

7918:susd2
gene id: 7918:susd2
uniprot id: W5M5J3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:vps18
gene id: 7918:vps18
uniprot id: W5N3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

7918:tecpr1
gene id: 7918:tecpr1
uniprot id: W5MQ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TECPR1 family.
messages: Lysosome membrane
messages: autophagosome membrane

7918:vps33a
gene id: 7918:vps33a
uniprot id: W5MDK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

7918:dnaja2
gene id: 7918:dnaja2
uniprot id: W5MDN1
names: Subcellular Location Annotation
messages: Membrane

7918:pigp
gene id: 7918:pigp
uniprot id: W5MCA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

7918:grid1
gene id: 7918:grid1
uniprot id: W5MP86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

7918:tmprss5
gene id: 7918:tmprss5
uniprot id: W5MAB0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:anapc13
gene id: 7918:anapc13
uniprot id: W5MBG0
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

7918:igf2bp3
gene id: 7918:igf2bp3
uniprot id: W5N0V6
names: Similarity
messages: Belongs to the RRM IMP/VICKZ family.

7918:themis2
gene id: 7918:themis2
uniprot id: W5M5F2
names: Similarity
messages: Belongs to the themis family.

7918:LOC102699181
gene id: 7918:LOC102699181
uniprot id: W5MRG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:cuedc2
gene id: 7918:cuedc2
uniprot id: W5MDZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

7918:rpa1
gene id: 7918:rpa1
uniprot id: W5MH73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

7918:LOC102689709
gene id: 7918:LOC102689709
uniprot id: W5NH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: Vacuole membrane

7918:gsk3b
gene id: 7918:gsk3b
uniprot id: W5MJG8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

7918:tssc4
gene id: 7918:tssc4
uniprot id: W5NLC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TSSC4 family.
messages: Cytoplasm
messages: Nucleus

7918:LOC102695473
gene id: 7918:LOC102695473
uniprot id: W5N6E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

7918:adamts8
gene id: 7918:adamts8
uniprot id: W5M9J1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:LOC102687801
gene id: 7918:LOC102687801
uniprot id: W5MD11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:fas
gene id: 7918:fas
uniprot id: W5MFY8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

7918:peli2
gene id: 7918:peli2
uniprot id: W5MZG0
names: Similarity
messages: Belongs to the pellino family.

7918:sec61g
gene id: 7918:sec61g
uniprot id: W5N7B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:dhrs7c
gene id: 7918:dhrs7c
uniprot id: W5MY09
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:olfm2
gene id: 7918:olfm2
uniprot id: W5MK23
uniprot id: W5MK37
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

7918:ppp1cc
gene id: 7918:ppp1cc
uniprot id: W5MKL1
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.

7918:nprl3
gene id: 7918:nprl3
uniprot id: W5MLV8
uniprot id: W5MLX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

7918:ptbp1
gene id: 7918:ptbp1
uniprot id: W5M0R2
names: Subcellular Location Annotation
messages: Nucleus

7918:cdca7l
gene id: 7918:cdca7l
uniprot id: W5N0L0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:LOC102690258
gene id: 7918:LOC102690258
uniprot id: W5MXC7
uniprot id: W5MXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

7918:hmmr
gene id: 7918:hmmr
uniprot id: W5MUN3
names: Subcellular Location Annotation
messages: spindle

7918:pgd
gene id: 7918:pgd
uniprot id: W5MI18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

7918:LOC102688516
gene id: 7918:LOC102688516
uniprot id: W5NBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

7918:lsm3
gene id: 7918:lsm3
uniprot id: W5N7V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

7918:gpm6b
gene id: 7918:gpm6b
uniprot id: W5MV83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

7918:nkx2-8
gene id: 7918:nkx2-8
uniprot id: W5N9E3
names: Subcellular Location Annotation
messages: Nucleus

7918:duoxa2
gene id: 7918:duoxa2
uniprot id: W5N8J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

7918:LOC102697805
gene id: 7918:LOC102697805
uniprot id: W5N0J0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

7918:fam46a
gene id: 7918:fam46a
uniprot id: W5NKC9
names: Similarity
messages: Belongs to the TENT family.

7918:arg2
gene id: 7918:arg2
uniprot id: W5NA25
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

7918:mef2c
gene id: 7918:mef2c
uniprot id: W5M184
names: Subcellular Location Annotation
messages: Nucleus

7918:limk1
gene id: 7918:limk1
uniprot id: W5MA28
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

7918:etv4
gene id: 7918:etv4
uniprot id: W5N2S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:phc3
gene id: 7918:phc3
uniprot id: W5MK80
names: Subcellular Location Annotation
messages: Nucleus

7918:pbx3
gene id: 7918:pbx3
uniprot id: W5LZC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

7918:atp2b4
gene id: 7918:atp2b4
uniprot id: W5N2F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:pdia4
gene id: 7918:pdia4
uniprot id: W5N712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

7918:ankrd34a
gene id: 7918:ankrd34a
uniprot id: W5NMC7
names: Similarity
messages: Belongs to the ANKRD34 family.

7918:ndufaf1
gene id: 7918:ndufaf1
uniprot id: W5N6U8
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

7918:cacnb4
gene id: 7918:cacnb4
uniprot id: W5M3R7
uniprot id: W5M3T8
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

7918:kitlg
gene id: 7918:kitlg
uniprot id: W5NHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

7918:psmc4
gene id: 7918:psmc4
uniprot id: W5MC82
names: Similarity
messages: Belongs to the AAA ATPase family.

7918:LOC102690768
gene id: 7918:LOC102690768
uniprot id: W5M7L8
names: Subcellular Location Annotation
messages: Membrane

7918:nudt6
gene id: 7918:nudt6
uniprot id: W5M4G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

7918:glg1
gene id: 7918:glg1
uniprot id: W5M034
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

7918:actg1
gene id: 7918:actg1
uniprot id: W5N532
names: Similarity
messages: Belongs to the actin family.

7918:nfia
gene id: 7918:nfia
uniprot id: W5MUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

7918:LOC107078821
gene id: 7918:LOC107078821
uniprot id: W5MWF1
names: Subcellular Location Annotation
messages: Membrane

7918:chrdl2
gene id: 7918:chrdl2
uniprot id: W5M2Q9
names: Subcellular Location Annotation
messages: Secreted

7918:psma2
gene id: 7918:psma2
uniprot id: W5MSJ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

7918:nadsyn1
gene id: 7918:nadsyn1
uniprot id: W5MCF0
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

7918:trappc5
gene id: 7918:trappc5
uniprot id: W5MI51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

7918:eif3m
gene id: 7918:eif3m
uniprot id: W5MAK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

7918:sdc1
gene id: 7918:sdc1
uniprot id: W5NKU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

7918:ttyh2
gene id: 7918:ttyh2
uniprot id: W5N5B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

7918:brk1
gene id: 7918:brk1
uniprot id: W5MXT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

7918:clg14h3orf58
gene id: 7918:clg14h3orf58
uniprot id: W5MM28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

7918:sult4a1
gene id: 7918:sult4a1
uniprot id: W5ND53
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

7918:mpp5
gene id: 7918:mpp5
uniprot id: W5N9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

7918:map2k3
gene id: 7918:map2k3
uniprot id: W5M1V0
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:LOC102690023
gene id: 7918:LOC102690023
uniprot id: W5MHP2
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Homotetramer.

7918:ogfrl1
gene id: 7918:ogfrl1
uniprot id: W5NKJ4
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

7918:ston2
gene id: 7918:ston2
uniprot id: W5MR97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating.
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: synaptosome

7918:csmd1
gene id: 7918:csmd1
uniprot id: W5NJM9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:KEF94 p08
gene id: 7918:KEF94_p08
uniprot id: Q8HQM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

7918:cad
gene id: 7918:cad
uniprot id: W5NFY8
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

7918:LOC102685380
gene id: 7918:LOC102685380
uniprot id: W5LZ75
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

7918:LOC107077559
gene id: 7918:LOC107077559
uniprot id: W5MJ66
names: Similarity
messages: Belongs to the EEIG family.

7918:gnl2
gene id: 7918:gnl2
uniprot id: W5MFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

7918:hint1
gene id: 7918:hint1
uniprot id: W5MNU4
names: Similarity
messages: Belongs to the HINT family.

7918:LOC102689708
gene id: 7918:LOC102689708
uniprot id: W5NCQ9
names: Similarity
messages: Belongs to the nucleoplasmin family.

7918:KEF94 p01
gene id: 7918:KEF94_p01
uniprot id: P29667
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme b groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and probably 6 low-molecular weight proteins.
messages: The full-length protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

7918:stx16
gene id: 7918:stx16
uniprot id: W5MGI8
names: Similarity
messages: Belongs to the syntaxin family.

7918:LOC102688511
gene id: 7918:LOC102688511
uniprot id: W5NP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

7918:hoxd13
gene id: 7918:hoxd13
uniprot id: W5MJV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

7918:foxp2
gene id: 7918:foxp2
uniprot id: V6F9B6
names: Subcellular Location Annotation
messages: Nucleus

7918:foxo1
gene id: 7918:foxo1
uniprot id: W5MQR6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:LOC102687731
gene id: 7918:LOC102687731
uniprot id: W5MHV4
names: Subcellular Location Annotation
messages: Membrane

7918:tpi1
gene id: 7918:tpi1
uniprot id: W5MME2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

7918:LOC102685535
gene id: 7918:LOC102685535
uniprot id: W5M5S8
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102692236
gene id: 7918:LOC102692236
uniprot id: W5M0H7
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

7918:LOC102695243
gene id: 7918:LOC102695243
uniprot id: W5NFE9
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

7918:lrp1b
gene id: 7918:lrp1b
uniprot id: W5LZ27
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:mapre3
gene id: 7918:mapre3
uniprot id: W5NHM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

7918:stk39
gene id: 7918:stk39
uniprot id: W5MNT0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

7918:mmp15
gene id: 7918:mmp15
uniprot id: W5MG61
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

7918:rrs1
gene id: 7918:rrs1
uniprot id: W5NMQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

7918:tmem159
gene id: 7918:tmem159
uniprot id: W5MMX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

7918:irg1
gene id: 7918:irg1
uniprot id: W5MGF4
names: Similarity
messages: Belongs to the PrpD family.

7918:pole
gene id: 7918:pole
uniprot id: W5M8S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

7918:rhbdl3
gene id: 7918:rhbdl3
uniprot id: W5N8I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

7918:nkain2
gene id: 7918:nkain2
uniprot id: W5NL43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

7918:toe1
gene id: 7918:toe1
uniprot id: W5M4Q7
names: Similarity
messages: Belongs to the CAF1 family.

7918:nelfcd
gene id: 7918:nelfcd
uniprot id: W5MGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

7918:LOC107077132
gene id: 7918:LOC107077132
uniprot id: W5N747
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

7918:gatsl3
gene id: 7918:gatsl3
uniprot id: W5M6Z5
names: Similarity
messages: Belongs to the GATS family.

7918:fermt2
gene id: 7918:fermt2
uniprot id: W5N2U4
uniprot id: W5N2U8
names: Similarity
messages: Belongs to the kindlin family.

7918:mtmr2
gene id: 7918:mtmr2
uniprot id: W5MLK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

7918:slc25a12
gene id: 7918:slc25a12
uniprot id: W5MLS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

7918:dlg1
gene id: 7918:dlg1
uniprot id: W5LZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Membrane

7918:rad23a
gene id: 7918:rad23a
uniprot id: W5MMT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

7918:mfsd11
gene id: 7918:mfsd11
uniprot id: W5MZK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

7918:smarcd2
gene id: 7918:smarcd2
uniprot id: W5N2B5
names: Similarity
messages: Belongs to the SMARCD family.

7918:tmem11
gene id: 7918:tmem11
uniprot id: W5M1Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Plays a role in mitochondrial morphogenesis.

7918:atp2a3
gene id: 7918:atp2a3
uniprot id: W5M457
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

7918:LOC102691108
gene id: 7918:LOC102691108
uniprot id: W5M208
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102698142
gene id: 7918:LOC102698142
uniprot id: W5N8N1
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

7918:pin4
gene id: 7918:pin4
uniprot id: W5NB50
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

7918:dcp1a
gene id: 7918:dcp1a
uniprot id: W5N9S2
names: Similarity
messages: Belongs to the DCP1 family.

7918:senp6
gene id: 7918:senp6
uniprot id: W5NJU0
names: Similarity
messages: Belongs to the peptidase C48 family.

7918:pnkd
gene id: 7918:pnkd
uniprot id: W5LXR2
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

7918:LOC102695098
gene id: 7918:LOC102695098
uniprot id: W5M3V2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

7918:abcc9
gene id: 7918:abcc9
uniprot id: W5NE67
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

7918:epha5
gene id: 7918:epha5
uniprot id: W5M460
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102683367
gene id: 7918:LOC102683367
uniprot id: W5LXX8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

7918:LOC102690405
gene id: 7918:LOC102690405
uniprot id: W5NCT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

7918:gdf5
gene id: 7918:gdf5
uniprot id: W5MLS9
names: Similarity
messages: Belongs to the TGF-beta family.

7918:LOC102684587
gene id: 7918:LOC102684587
uniprot id: W5N9G2
names: Similarity
messages: Belongs to the peptidase C2 family.

7918:cul5
gene id: 7918:cul5
uniprot id: W5MIC5
names: Similarity
messages: Belongs to the cullin family.

7918:LOC102693222
gene id: 7918:LOC102693222
uniprot id: W5N9M3
names: Similarity
messages: Belongs to the alpha-actinin family.

7918:mrpl18
gene id: 7918:mrpl18
uniprot id: W5MN90
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

7918:LOC107076885
gene id: 7918:LOC107076885
uniprot id: W5NET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

7918:magt1
gene id: 7918:magt1
uniprot id: W5N8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:use1
gene id: 7918:use1
uniprot id: W5M9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:xrcc6bp1
gene id: 7918:xrcc6bp1
uniprot id: W5NIH1
names: Similarity
messages: Belongs to the peptidase M76 family.

7918:edn1
gene id: 7918:edn1
uniprot id: W5MMT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

7918:copz1
gene id: 7918:copz1
uniprot id: W5MHL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

7918:cdc20b
gene id: 7918:cdc20b
uniprot id: W5M3M4
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

7918:mllt3
gene id: 7918:mllt3
uniprot id: W5MZN4
names: Subcellular Location Annotation
messages: Nucleus

7918:rtfdc1
gene id: 7918:rtfdc1
uniprot id: W5MJ83
names: Similarity
messages: Belongs to the rtf2 family.

7918:grin2a
gene id: 7918:grin2a
uniprot id: W5MGJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

7918:nr1h4
gene id: 7918:nr1h4
uniprot id: W5NDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

7918:LOC102685598
gene id: 7918:LOC102685598
uniprot id: W5MAJ2
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

7918:LOC102687673
gene id: 7918:LOC102687673
uniprot id: W5NBW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

7918:thbs2
gene id: 7918:thbs2
uniprot id: W5NHC5
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:irf6
gene id: 7918:irf6
uniprot id: W5MZS6
names: Subcellular Location Annotation
messages: Nucleus

7918:ppp1r14c
gene id: 7918:ppp1r14c
uniprot id: W5NH63
names: Similarity
messages: Belongs to the PP1 inhibitor family.

7918:clg27h11orf58
gene id: 7918:clg27h11orf58
uniprot id: W5M5D3
names: Similarity
messages: Belongs to the SMAP family.

7918:LOC102692294
gene id: 7918:LOC102692294
uniprot id: W5MS42
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:apitd1
gene id: 7918:apitd1
uniprot id: W5MHY6
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

7918:rap1gds1
gene id: 7918:rap1gds1
uniprot id: W5N4U6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion

7918:ears2
gene id: 7918:ears2
uniprot id: W5M904
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

7918:kcnj6
gene id: 7918:kcnj6
uniprot id: W5MC31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

7918:lrwd1
gene id: 7918:lrwd1
uniprot id: W5M180
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

7918:tfpi2
gene id: 7918:tfpi2
uniprot id: W5MXW7
names: Subcellular Location Annotation
messages: Secreted

7918:cct5
gene id: 7918:cct5
uniprot id: W5N7V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

7918:tmem63a
gene id: 7918:tmem63a
uniprot id: W5NF34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

7918:LOC102687840
gene id: 7918:LOC102687840
uniprot id: W5NJ14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:LOC102694832
gene id: 7918:LOC102694832
uniprot id: W5N819
names: Similarity
messages: Belongs to the intermediate filament family.

7918:ski
gene id: 7918:ski
uniprot id: W5MEW2
names: Similarity
messages: Belongs to the SKI family.

7918:smarca5
gene id: 7918:smarca5
uniprot id: W5MRD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

7918:phactr1
gene id: 7918:phactr1
uniprot id: W5N6A3
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

7918:sec24a
gene id: 7918:sec24a
uniprot id: W5MVR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

7918:LOC102689667
gene id: 7918:LOC102689667
uniprot id: W5MCJ4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:rnpep
gene id: 7918:rnpep
uniprot id: W5MVB4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

7918:ltv1
gene id: 7918:ltv1
uniprot id: W5NEE5
names: Similarity
messages: Belongs to the LTV1 family.

7918:gtf2a1
gene id: 7918:gtf2a1
uniprot id: W5MR56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

7918:stard5
gene id: 7918:stard5
uniprot id: W5N597
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

7918:LOC102683439
gene id: 7918:LOC102683439
uniprot id: W5MF26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:suds3
gene id: 7918:suds3
uniprot id: W5M654
names: Subcellular Location Annotation
messages: Nucleus

7918:jph3
gene id: 7918:jph3
uniprot id: W5M731
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

7918:LOC102683020
gene id: 7918:LOC102683020
uniprot id: W5NJ97
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:atp6ap1l
gene id: 7918:atp6ap1l
uniprot id: W5N6V3
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

7918:LOC107075635
gene id: 7918:LOC107075635
uniprot id: W5LYS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

7918:orc6
gene id: 7918:orc6
uniprot id: W5ME12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

7918:LOC102688210
gene id: 7918:LOC102688210
uniprot id: W5M4B5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:atp5c1
gene id: 7918:atp5c1
uniprot id: W5NF95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

7918:msn
gene id: 7918:msn
uniprot id: W5NBL6
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

7918:pmch
gene id: 7918:pmch
uniprot id: W5NDG8
names: Function
messages: Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH.

7918:kif9
gene id: 7918:kif9
uniprot id: W5MVP2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:mllt11
gene id: 7918:mllt11
uniprot id: W5NMC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

7918:hpgd
gene id: 7918:hpgd
uniprot id: W5N808
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:epcam
gene id: 7918:epcam
uniprot id: W5NHL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:ralb
gene id: 7918:ralb
uniprot id: W5M1R5
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:sema7a
gene id: 7918:sema7a
uniprot id: W5NCK2
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ints2
gene id: 7918:ints2
uniprot id: W5M7Q9
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

7918:LOC102694803
gene id: 7918:LOC102694803
uniprot id: W5MC62
names: Similarity
messages: Belongs to the peptidase S9A family.

7918:rsl24d1
gene id: 7918:rsl24d1
uniprot id: W5N7G9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

7918:tnrc6a
gene id: 7918:tnrc6a
uniprot id: W5ME56
names: Similarity
messages: Belongs to the GW182 family.

7918:dll1
gene id: 7918:dll1
uniprot id: W5NEK8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

7918:elavl2
gene id: 7918:elavl2
uniprot id: W5N4C1
names: Similarity
messages: Belongs to the RRM elav family.

7918:usp9x
gene id: 7918:usp9x
uniprot id: W5M2K6
names: Similarity
messages: Belongs to the peptidase C19 family.

7918:rell1
gene id: 7918:rell1
uniprot id: W5MTS3
names: Similarity
messages: Belongs to the RELT family.

7918:gpd2
gene id: 7918:gpd2
uniprot id: W5MEZ6
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

7918:rpl8
gene id: 7918:rpl8
uniprot id: W5M2G6
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

7918:ghsr
gene id: 7918:ghsr
uniprot id: W5ML13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:znf532
gene id: 7918:znf532
uniprot id: W5N1X7
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

7918:sfrp4
gene id: 7918:sfrp4
uniprot id: W5N0A5
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:hlcs
gene id: 7918:hlcs
uniprot id: W5MCE9
names: Similarity
messages: Belongs to the biotin--protein ligase family.

7918:LOC102692742
gene id: 7918:LOC102692742
uniprot id: W5N052
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:LOC102691411
gene id: 7918:LOC102691411
uniprot id: W5NH25
names: Similarity
messages: Belongs to the type II (or gamma) interferon family.

7918:mrpl13
gene id: 7918:mrpl13
uniprot id: W5MS71
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

7918:ndufs7
gene id: 7918:ndufs7
uniprot id: W5M2T0
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

7918:vapa
gene id: 7918:vapa
uniprot id: W5M365
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:trpt1
gene id: 7918:trpt1
uniprot id: W5LZH1
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

7918:LOC102690807
gene id: 7918:LOC102690807
uniprot id: W5MYD5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

7918:htr1f
gene id: 7918:htr1f
uniprot id: W5NLL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

7918:polr3k
gene id: 7918:polr3k
uniprot id: W5MLE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

7918:kcnk12
gene id: 7918:kcnk12
uniprot id: W5NHK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

7918:LOC102694708
gene id: 7918:LOC102694708
uniprot id: W5NM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:ncl
gene id: 7918:ncl
uniprot id: W5MBP1
names: Subcellular Location Annotation
messages: nucleolus

7918:ddx59
gene id: 7918:ddx59
uniprot id: W5MLV1
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

7918:dkk1
gene id: 7918:dkk1
uniprot id: W5MH02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

7918:gatsl2
gene id: 7918:gatsl2
uniprot id: W5M1K9
names: Similarity
messages: Belongs to the GATS family.

7918:usmg5
gene id: 7918:usmg5
uniprot id: W5N1L3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

7918:vil1
gene id: 7918:vil1
uniprot id: W5MRH2
names: Similarity
messages: Belongs to the villin/gelsolin family.

7918:glp2r
gene id: 7918:glp2r
uniprot id: W5N1N4
names: Subcellular Location Annotation
messages: Membrane

7918:noc3l
gene id: 7918:noc3l
uniprot id: W5MFN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Belongs to the FAM114 family.
messages: nucleolus

7918:frg1
gene id: 7918:frg1
uniprot id: W5N8Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

7918:rpl27a
gene id: 7918:rpl27a
uniprot id: W5M6F2
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

7918:sumf2
gene id: 7918:sumf2
uniprot id: W5M9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

7918:gdpd4
gene id: 7918:gdpd4
uniprot id: W5MHW3
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

7918:usp15
gene id: 7918:usp15
uniprot id: W5NK48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

7918:ppp1r1b
gene id: 7918:ppp1r1b
uniprot id: W5N4Y1
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

7918:sntg1
gene id: 7918:sntg1
uniprot id: W5MFP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

7918:cbfb
gene id: 7918:cbfb
uniprot id: W5MMK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

7918:LOC102696250
gene id: 7918:LOC102696250
uniprot id: W5M312
names: Subcellular Location Annotation
messages: Cytoplasm

7918:tlx2
gene id: 7918:tlx2
uniprot id: W5M1L9
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102698346
gene id: 7918:LOC102698346
uniprot id: W5NDE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

7918:cpq
gene id: 7918:cpq
uniprot id: W5M6J2
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome

7918:LOC102688995
gene id: 7918:LOC102688995
uniprot id: W5MF72
names: Similarity
messages: Belongs to the folate receptor family.

7918:tbr1
gene id: 7918:tbr1
uniprot id: W5MPY0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

7918:LOC102699247
gene id: 7918:LOC102699247
uniprot id: W5MH78
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

7918:LOC107077872
gene id: 7918:LOC107077872
uniprot id: W5NA93
names: Subcellular Location Annotation
messages: Membrane

7918:ext1
gene id: 7918:ext1
uniprot id: W5M5Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

7918:igf2bp1
gene id: 7918:igf2bp1
uniprot id: W5N7N8
names: Similarity
messages: Belongs to the RRM IMP/VICKZ family.

7918:agl
gene id: 7918:agl
uniprot id: W5LYQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

7918:pde6g
gene id: 7918:pde6g
uniprot id: W5N5Y3
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

7918:ren
gene id: 7918:ren
uniprot id: W5N2H9
names: Similarity
messages: Belongs to the peptidase A1 family.

7918:bmp2
gene id: 7918:bmp2
uniprot id: W5NI48
names: Similarity
messages: Belongs to the TGF-beta family.

7918:fuz
gene id: 7918:fuz
uniprot id: W5NNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

7918:slc39a11
gene id: 7918:slc39a11
uniprot id: W5N414
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102684154
gene id: 7918:LOC102684154
uniprot id: W5LYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

7918:fnip1
gene id: 7918:fnip1
uniprot id: W5MW72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

7918:pml
gene id: 7918:pml
uniprot id: W5NCN0
names: Subcellular Location Annotation
messages: Cytoplasm

7918:LOC102691862
gene id: 7918:LOC102691862
uniprot id: W5N6L0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

7918:hmbox1
gene id: 7918:hmbox1
uniprot id: W5NGE0
names: Subcellular Location Annotation
messages: Nucleus

7918:leprotl1
gene id: 7918:leprotl1
uniprot id: W5M427
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

7918:sox12
gene id: 7918:sox12
uniprot id: W5NPA7
names: Subcellular Location Annotation
messages: Nucleus

7918:arhgdig
gene id: 7918:arhgdig
uniprot id: W5MGW3
uniprot id: W5MGY7
names: Similarity
messages: Belongs to the Rho GDI family.

7918:adam10
gene id: 7918:adam10
uniprot id: W5N829
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:adnp
gene id: 7918:adnp
uniprot id: W5M545
names: Subcellular Location Annotation
messages: Nucleus

7918:insr
gene id: 7918:insr
uniprot id: W5M9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

7918:nkx6-1
gene id: 7918:nkx6-1
uniprot id: W5N2S7
names: Subcellular Location Annotation
messages: Nucleus

7918:cacna1e
gene id: 7918:cacna1e
uniprot id: W5MTZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane

7918:dnah7
gene id: 7918:dnah7
uniprot id: W5MCJ1
names: Similarity
messages: Belongs to the dynein heavy chain family.

7918:anapc10
gene id: 7918:anapc10
uniprot id: W5MR58
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

7918:clg2h5orf28
gene id: 7918:clg2h5orf28
uniprot id: W5N3J3
names: Subcellular Location Annotation
messages: Membrane

7918:mrps12
gene id: 7918:mrps12
uniprot id: W5LWT4
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

7918:trim42
gene id: 7918:trim42
uniprot id: W5M9P7
names: Subcellular Location Annotation
messages: Cytoplasm

7918:jakmip2
gene id: 7918:jakmip2
uniprot id: W5MY04
names: Similarity
messages: Belongs to the JAKMIP family.

7918:LOC102682840
gene id: 7918:LOC102682840
uniprot id: W5MQP4
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:hspd1
gene id: 7918:hspd1
uniprot id: W5M8K0
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

7918:polg
gene id: 7918:polg
uniprot id: W5NBB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-A family.
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

7918:LOC102698385
gene id: 7918:LOC102698385
uniprot id: W5MF55
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

7918:LOC102697276
gene id: 7918:LOC102697276
uniprot id: W5NEV8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

7918:itm2c
gene id: 7918:itm2c
uniprot id: W5MAI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

7918:smim12
gene id: 7918:smim12
uniprot id: W5NP14
names: Similarity
messages: Belongs to the SMIM12 family.

7918:gpr132
gene id: 7918:gpr132
uniprot id: W5NMG1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:alox12
gene id: 7918:alox12
uniprot id: W5N9Q5
names: Caution
names: Cofactor
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC107078106
gene id: 7918:LOC107078106
uniprot id: W5NKL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

7918:LOC102685347
gene id: 7918:LOC102685347
uniprot id: W5MF66
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

7918:rnf13
gene id: 7918:rnf13
uniprot id: W5M104
names: Subcellular Location Annotation
messages: Membrane

7918:ppa1
gene id: 7918:ppa1
uniprot id: W5MCY0
names: Similarity
messages: Belongs to the PPase family.

7918:st8sia4
gene id: 7918:st8sia4
uniprot id: W5MRP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:pik3c3
gene id: 7918:pik3c3
uniprot id: W5MSW6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

7918:adck2
gene id: 7918:adck2
uniprot id: W5NIZ9
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

7918:LOC102689809
gene id: 7918:LOC102689809
uniprot id: W5MN61
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

7918:mgst2
gene id: 7918:mgst2
uniprot id: W5MWX1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:lhx4
gene id: 7918:lhx4
uniprot id: W5MSB5
names: Subcellular Location Annotation
messages: Nucleus

7918:plk3
gene id: 7918:plk3
uniprot id: W5M3D5
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

7918:dbnl
gene id: 7918:dbnl
uniprot id: W5ND24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Early endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

7918:glrb
gene id: 7918:glrb
uniprot id: W5MNI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

7918:pdp2
gene id: 7918:pdp2
uniprot id: W5NM37
names: Similarity
messages: Belongs to the PP2C family.

7918:rab3c
gene id: 7918:rab3c
uniprot id: W5MLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

7918:sepsecs
gene id: 7918:sepsecs
uniprot id: W5N3E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

7918:arg1
gene id: 7918:arg1
uniprot id: W5NIT3
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

7918:rpl7l1
gene id: 7918:rpl7l1
uniprot id: W5NG12
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

7918:tmem33
gene id: 7918:tmem33
uniprot id: W5N5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

7918:LOC102684476
gene id: 7918:LOC102684476
uniprot id: W5MFT5
names: Subcellular Location Annotation
messages: Membrane

7918:dtx1
gene id: 7918:dtx1
uniprot id: W5MNG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

7918:rxra
gene id: 7918:rxra
uniprot id: W5MAT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

7918:baiap2
gene id: 7918:baiap2
uniprot id: W5N5K8
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

7918:spock2
gene id: 7918:spock2
uniprot id: W5MD62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:asic4
gene id: 7918:asic4
uniprot id: W5LXB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Cell membrane
messages: Membrane

7918:cep44
gene id: 7918:cep44
uniprot id: W5N800
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

7918:fgf9
gene id: 7918:fgf9
uniprot id: W5M0T9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

7918:LOC102694489
gene id: 7918:LOC102694489
uniprot id: W5N678
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

7918:sephs1
gene id: 7918:sephs1
uniprot id: W5NJ81
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

7918:kcns2
gene id: 7918:kcns2
uniprot id: W5NP83
names: Subcellular Location Annotation
messages: Membrane

7918:il12a
gene id: 7918:il12a
uniprot id: W5M7R3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

7918:nsun5
gene id: 7918:nsun5
uniprot id: W5LYP3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

7918:id2
gene id: 7918:id2
uniprot id: W5NJH0
names: Subcellular Location Annotation
messages: Nucleus

7918:st3gal1
gene id: 7918:st3gal1
uniprot id: A0A0F7RQ81
uniprot id: W5M7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:glo1
gene id: 7918:glo1
uniprot id: W5NKA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

7918:mcm7
gene id: 7918:mcm7
uniprot id: W5N653
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

7918:gal3st1
gene id: 7918:gal3st1
uniprot id: W5M8H2
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

7918:acox3
gene id: 7918:acox3
uniprot id: W5MW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

7918:man2a2
gene id: 7918:man2a2
uniprot id: W5ND75
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

7918:flt1
gene id: 7918:flt1
uniprot id: W5MA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:pomgnt2
gene id: 7918:pomgnt2
uniprot id: W5NP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:hapln1
gene id: 7918:hapln1
uniprot id: W5M1N6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102696345
gene id: 7918:LOC102696345
uniprot id: W5M4J0
uniprot id: W5M4L4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

7918:atg4b
gene id: 7918:atg4b
uniprot id: W5MHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

7918:mrps33
gene id: 7918:mrps33
uniprot id: W5NGV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

7918:ckb
gene id: 7918:ckb
uniprot id: W5MUQ6
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

7918:sptlc3
gene id: 7918:sptlc3
uniprot id: W5NGB0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

7918:LOC102695107
gene id: 7918:LOC102695107
uniprot id: W5M3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

7918:LOC102689871
gene id: 7918:LOC102689871
uniprot id: W5NEI1
names: Similarity
messages: Belongs to the actin family.

7918:atpaf2
gene id: 7918:atpaf2
uniprot id: W5MQS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

7918:galnt10
gene id: 7918:galnt10
uniprot id: W5N3U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:smc2
gene id: 7918:smc2
uniprot id: W5N738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Chromosome
messages: Nucleus

7918:clrn1
gene id: 7918:clrn1
uniprot id: W5M1H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

7918:scamp2
gene id: 7918:scamp2
uniprot id: W5NCP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

7918:LOC102685634
gene id: 7918:LOC102685634
uniprot id: W5LZZ3
names: Similarity
messages: Belongs to the peptidase C2 family.

7918:shh
gene id: 7918:shh
uniprot id: W5N409
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

7918:ssx2ip
gene id: 7918:ssx2ip
uniprot id: W5MEG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

7918:LOC102693997
gene id: 7918:LOC102693997
uniprot id: W5N9E7
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

7918:ube2c
gene id: 7918:ube2c
uniprot id: W5MIB3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:ncapg
gene id: 7918:ncapg
uniprot id: W5M695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

7918:rita1
gene id: 7918:rita1
uniprot id: W5MPK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RITA family.
messages: Cytoplasm
messages: Interacts with RBPJ/RBPSUH.
messages: Nucleus
messages: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

7918:LOC102695161
gene id: 7918:LOC102695161
uniprot id: W5MAM8
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

7918:dok6
gene id: 7918:dok6
uniprot id: W5M767
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

7918:LOC102697609
gene id: 7918:LOC102697609
uniprot id: W5LXU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:fam118b
gene id: 7918:fam118b
uniprot id: W5M4E3
names: Similarity
messages: Belongs to the FAM118 family.

7918:nxph2
gene id: 7918:nxph2
uniprot id: W5LYF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

7918:setd3
gene id: 7918:setd3
uniprot id: W5MQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

7918:tbl1x
gene id: 7918:tbl1x
uniprot id: W5MVH7
names: Similarity
messages: Belongs to the WD repeat EBI family.

7918:ift57
gene id: 7918:ift57
uniprot id: W5N4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

7918:hspa14
gene id: 7918:hspa14
uniprot id: W5NJ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

7918:mbtps2
gene id: 7918:mbtps2
uniprot id: W5M7V7
names: Similarity
messages: Belongs to the peptidase M50A family.

7918:casr
gene id: 7918:casr
uniprot id: W5M4V1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:heph
gene id: 7918:heph
uniprot id: W5NBN3
names: Similarity
messages: Belongs to the multicopper oxidase family.

7918:chac2
gene id: 7918:chac2
uniprot id: W5NHG0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

7918:ska2
gene id: 7918:ska2
uniprot id: W5LZ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

7918:slc25a37
gene id: 7918:slc25a37
uniprot id: W5NCX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:chst14
gene id: 7918:chst14
uniprot id: W5N9H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:scamp4
gene id: 7918:scamp4
uniprot id: W5MHP7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:gabrb3
gene id: 7918:gabrb3
uniprot id: W5MP27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:unk
gene id: 7918:unk
uniprot id: W5N0S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

7918:LOC102695769
gene id: 7918:LOC102695769
uniprot id: W5N9J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:as3mt
gene id: 7918:as3mt
uniprot id: W5N1D6
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

7918:slc39a4
gene id: 7918:slc39a4
uniprot id: W5MLB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

7918:upf1
gene id: 7918:upf1
uniprot id: W5M218
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

7918:tmem102
gene id: 7918:tmem102
uniprot id: W5N8J7
names: Similarity
messages: Belongs to the mab-21 family.

7918:fah
gene id: 7918:fah
uniprot id: W5N514
names: Similarity
messages: Belongs to the FAH family.

7918:dnm3
gene id: 7918:dnm3
uniprot id: W5MWQ0
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

7918:arpc5l
gene id: 7918:arpc5l
uniprot id: W5MCI5
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

7918:osbpl8
gene id: 7918:osbpl8
uniprot id: W5NHG7
names: Similarity
messages: Belongs to the OSBP family.

7918:LOC102695042
gene id: 7918:LOC102695042
uniprot id: W5MNV2
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC107079407
gene id: 7918:LOC107079407
uniprot id: W5M3R5
names: Subcellular Location Annotation
messages: Membrane

7918:pdgfa
gene id: 7918:pdgfa
uniprot id: W5M076
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

7918:dag1
gene id: 7918:dag1
uniprot id: W5N7A6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

7918:atp2a2
gene id: 7918:atp2a2
uniprot id: W5MJY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

7918:LOC102689598
gene id: 7918:LOC102689598
uniprot id: W5N2U0
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102682574
gene id: 7918:LOC102682574
uniprot id: W5NBW2
names: Similarity
messages: Belongs to the Toll-like receptor family.

7918:tjp1
gene id: 7918:tjp1
uniprot id: W5N8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

7918:LOC102695063
gene id: 7918:LOC102695063
uniprot id: W5NA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

7918:gas8
gene id: 7918:gas8
uniprot id: W5LYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum
messages: flagellum axoneme

7918:trappc4
gene id: 7918:trappc4
uniprot id: W5M665
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

7918:LOC102689159
gene id: 7918:LOC102689159
uniprot id: W5NGP6
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

7918:kcnv2
gene id: 7918:kcnv2
uniprot id: W5N460
names: Subcellular Location Annotation
messages: Membrane

7918:wasl
gene id: 7918:wasl
uniprot id: W5NFX1
names: Subcellular Location Annotation
messages: Nucleus

7918:tsg101
gene id: 7918:tsg101
uniprot id: W5LXD4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

7918:klhl22
gene id: 7918:klhl22
uniprot id: W5MHL9
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

7918:rad23b
gene id: 7918:rad23b
uniprot id: W5MUZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

7918:polr3f
gene id: 7918:polr3f
uniprot id: W5NFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

7918:LOC102698342
gene id: 7918:LOC102698342
uniprot id: W5MQC5
uniprot id: W5MQD8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:tlcd1
gene id: 7918:tlcd1
uniprot id: W5MF85
names: Subcellular Location Annotation
messages: Membrane

7918:mdm1
gene id: 7918:mdm1
uniprot id: W5NH29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM1 family.
messages: Nucleus
messages: centriole

7918:LOC102688993
gene id: 7918:LOC102688993
uniprot id: W5LYI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

7918:LOC102693879
gene id: 7918:LOC102693879
uniprot id: W5NN24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:LOC102685348
gene id: 7918:LOC102685348
uniprot id: W5MVW3
names: Similarity
messages: Belongs to the sulfatase family.

7918:nlgn4x
gene id: 7918:nlgn4x
uniprot id: W5MVQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

7918:LOC102682912
gene id: 7918:LOC102682912
uniprot id: W5N0I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

7918:ntsr1
gene id: 7918:ntsr1
uniprot id: W5MFM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:ocln
gene id: 7918:ocln
uniprot id: W5M9V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

7918:LOC102692297
gene id: 7918:LOC102692297
uniprot id: W5MPX7
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

7918:lyn
gene id: 7918:lyn
uniprot id: W5MDZ9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:ppt1
gene id: 7918:ppt1
uniprot id: W5LXU3
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

7918:sulf1
gene id: 7918:sulf1
uniprot id: W5M9I4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

7918:clg7h14orf159
gene id: 7918:clg7h14orf159
uniprot id: W5N6H3
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

7918:c8g
gene id: 7918:c8g
uniprot id: W5M6A1
names: Subcellular Location Annotation
messages: Secreted

7918:eya3
gene id: 7918:eya3
uniprot id: W5M9M0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

7918:nkd1
gene id: 7918:nkd1
uniprot id: W5MKH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

7918:hs6st1
gene id: 7918:hs6st1
uniprot id: W5MIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

7918:sox2
gene id: 7918:sox2
uniprot id: W5NLE2
names: Subcellular Location Annotation
messages: Nucleus

7918:aqp3
gene id: 7918:aqp3
uniprot id: W5MCD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

7918:pnrc2
gene id: 7918:pnrc2
uniprot id: W5NP31
names: Subcellular Location Annotation
messages: Nucleus

7918:psma4
gene id: 7918:psma4
uniprot id: W5NCY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

7918:taf1
gene id: 7918:taf1
uniprot id: W5NCD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

7918:fgf14
gene id: 7918:fgf14
uniprot id: W5M4E9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

7918:dnpep
gene id: 7918:dnpep
uniprot id: W5MX98
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

7918:slc18b1
gene id: 7918:slc18b1
uniprot id: W5NHB1
names: Subcellular Location Annotation
messages: Membrane

7918:malsu1
gene id: 7918:malsu1
uniprot id: W5N0T0
names: Similarity
messages: Belongs to the Iojap/RsfS family.

7918:LOC102688897
gene id: 7918:LOC102688897
uniprot id: W5MW30
names: Subcellular Location Annotation
messages: centrosome

7918:cbl
gene id: 7918:cbl
uniprot id: W5M6I7
names: Domain
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

7918:lnpep
gene id: 7918:lnpep
uniprot id: W5MGX3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

7918:LOC102699211
gene id: 7918:LOC102699211
uniprot id: W5MTR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

7918:LOC102694942
gene id: 7918:LOC102694942
uniprot id: W5N147
names: Subcellular Location Annotation
messages: Membrane

7918:neil3
gene id: 7918:neil3
uniprot id: W5N860
names: Similarity
messages: Belongs to the FPG family.

7918:grk7
gene id: 7918:grk7
uniprot id: W5MN03
uniprot id: W5MN20
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

7918:bfsp1
gene id: 7918:bfsp1
uniprot id: W5NGE6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

7918:oprl1
gene id: 7918:oprl1
uniprot id: W5MDA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
messages: Membrane
messages: Vesicle

7918:smc4
gene id: 7918:smc4
uniprot id: W5M7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family.
messages: Chromosome
messages: Nucleus

7918:ube2t
gene id: 7918:ube2t
uniprot id: W5MTT3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:gns
gene id: 7918:gns
uniprot id: W5NKE0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

7918:seh1l
gene id: 7918:seh1l
uniprot id: W5MTL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

7918:mrpl2
gene id: 7918:mrpl2
uniprot id: W5NFY9
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

7918:ccdc107
gene id: 7918:ccdc107
uniprot id: W5NHE4
names: Similarity
messages: Belongs to the ric-3 family.

7918:LOC102692312
gene id: 7918:LOC102692312
uniprot id: W5M1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

7918:nkap
gene id: 7918:nkap
uniprot id: W5NDP5
names: Similarity
messages: Belongs to the NKAP family.

7918:LOC102684982
gene id: 7918:LOC102684982
uniprot id: W5LZ00
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

7918:LOC102690679
gene id: 7918:LOC102690679
uniprot id: W5NGJ5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

7918:LOC102695862
gene id: 7918:LOC102695862
uniprot id: W5MDW4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:atg4d
gene id: 7918:atg4d
uniprot id: W5MMA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

7918:pdcl2
gene id: 7918:pdcl2
uniprot id: W5N9J6
names: Similarity
messages: Belongs to the phosducin family.

7918:echdc1
gene id: 7918:echdc1
uniprot id: W5NID6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

7918:pygb
gene id: 7918:pygb
uniprot id: W5NJD1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

7918:rnasek
gene id: 7918:rnasek
uniprot id: W5N9P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

7918:mapre2
gene id: 7918:mapre2
uniprot id: W5MGA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

7918:tmem214
gene id: 7918:tmem214
uniprot id: W5NHM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:LOC102693167
gene id: 7918:LOC102693167
uniprot id: W5MG56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:ccbe1
gene id: 7918:ccbe1
uniprot id: W5N233
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:cand2
gene id: 7918:cand2
uniprot id: W5N7R7
names: Similarity
messages: Belongs to the CAND family.

7918:supt4h1
gene id: 7918:supt4h1
uniprot id: W5M539
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

7918:evx1
gene id: 7918:evx1
uniprot id: W5N1S2
names: Subcellular Location Annotation
messages: Nucleus

7918:lhfpl5
gene id: 7918:lhfpl5
uniprot id: W5MZ94
names: Subcellular Location Annotation
messages: Membrane

7918:npc2
gene id: 7918:npc2
uniprot id: W5MY41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

7918:tpt1
gene id: 7918:tpt1
uniprot id: W5ME16
names: Similarity
messages: Belongs to the TCTP family.

7918:erh
gene id: 7918:erh
uniprot id: W5N764
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

7918:LOC102685175
gene id: 7918:LOC102685175
uniprot id: W5MI36
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

7918:kif3a
gene id: 7918:kif3a
uniprot id: W5MWK4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:LOC107077831
gene id: 7918:LOC107077831
uniprot id: W5N827
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle
messages: nucleoplasm

7918:LOC102689984
gene id: 7918:LOC102689984
uniprot id: W5MUD4
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

7918:gsto1
gene id: 7918:gsto1
uniprot id: W5N1U0
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

7918:lonp1
gene id: 7918:lonp1
uniprot id: W5M5N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

7918:ctnna3
gene id: 7918:ctnna3
uniprot id: W5N0W2
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

7918:eml6
gene id: 7918:eml6
uniprot id: W5NES5
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

7918:LOC107076529
gene id: 7918:LOC107076529
uniprot id: W5N5P8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:atl2
gene id: 7918:atl2
uniprot id: W5NFN4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

7918:sh3gl3
gene id: 7918:sh3gl3
uniprot id: W5N5G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

7918:mtfr2
gene id: 7918:mtfr2
uniprot id: W5NH75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

7918:LOC102689937
gene id: 7918:LOC102689937
uniprot id: W5MZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:padi2
gene id: 7918:padi2
uniprot id: W5M555
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Cytoplasm

7918:LOC102691691
gene id: 7918:LOC102691691
uniprot id: W5M976
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

7918:LOC102685072
gene id: 7918:LOC102685072
uniprot id: W5MUZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

7918:LOC102686393
gene id: 7918:LOC102686393
uniprot id: W5NEQ2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

7918:cd40lg
gene id: 7918:cd40lg
uniprot id: W5NDA5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

7918:LOC102691618
gene id: 7918:LOC102691618
uniprot id: W5MR76
names: Subcellular Location Annotation
messages: Nucleus

7918:chd2
gene id: 7918:chd2
uniprot id: W5NAQ3
names: Subcellular Location Annotation
messages: Nucleus

7918:ucp1
gene id: 7918:ucp1
uniprot id: W5MRW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:ccser2
gene id: 7918:ccser2
uniprot id: W5MPE2
names: Similarity
messages: Belongs to the CCSER family.

7918:cmtm4
gene id: 7918:cmtm4
uniprot id: W5MCK2
names: Subcellular Location Annotation
messages: Membrane

7918:pnpla7
gene id: 7918:pnpla7
uniprot id: W5M1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:immp1l
gene id: 7918:immp1l
uniprot id: W5MAZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

7918:bambi
gene id: 7918:bambi
uniprot id: W5MKP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

7918:tppp3
gene id: 7918:tppp3
uniprot id: W5MNL1
names: Similarity
messages: Belongs to the TPPP family.

7918:klhl21
gene id: 7918:klhl21
uniprot id: W5M4G2
names: Subcellular Location Annotation
messages: spindle

7918:ppp6r3
gene id: 7918:ppp6r3
uniprot id: W5M3P7
names: Similarity
messages: Belongs to the SAPS family.

7918:prdm16
gene id: 7918:prdm16
uniprot id: W5MDI2
names: Subcellular Location Annotation
messages: Nucleus

7918:ganc
gene id: 7918:ganc
uniprot id: W5N6Y0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

7918:cct3
gene id: 7918:cct3
uniprot id: W5MK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

7918:ccnb1
gene id: 7918:ccnb1
uniprot id: W5MWV3
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

7918:gtf2h3
gene id: 7918:gtf2h3
uniprot id: W5MFF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

7918:tph2
gene id: 7918:tph2
uniprot id: W5NHD0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

7918:dok4
gene id: 7918:dok4
uniprot id: W5MFJ8
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

7918:gpn3
gene id: 7918:gpn3
uniprot id: W5MK66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

7918:kynu
gene id: 7918:kynu
uniprot id: W5LZ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.

7918:pcmt1
gene id: 7918:pcmt1
uniprot id: W5NK67
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

7918:LOC102692902
gene id: 7918:LOC102692902
uniprot id: W5M747
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

7918:rffl
gene id: 7918:rffl
uniprot id: W5LY12
names: Subcellular Location Annotation
messages: Cell membrane

7918:LOC102685124
gene id: 7918:LOC102685124
uniprot id: W5MRK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

7918:dpys
gene id: 7918:dpys
uniprot id: W5MT36
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

7918:ube2d2
gene id: 7918:ube2d2
uniprot id: W5N4F2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:spata6
gene id: 7918:spata6
uniprot id: W5MSJ6
names: Similarity
messages: Belongs to the SPATA6 family.

7918:stard8
gene id: 7918:stard8
uniprot id: W5NBS6
names: Subcellular Location Annotation
messages: Cytoplasm

7918:ext2
gene id: 7918:ext2
uniprot id: W5M4K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

7918:esr1
gene id: 7918:esr1
uniprot id: W5NHJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer. Can form a heterodimer with ER-beta.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

7918:dcaf10
gene id: 7918:dcaf10
uniprot id: W5N2Q3
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

7918:hs6st3
gene id: 7918:hs6st3
uniprot id: W5MD23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

7918:evc
gene id: 7918:evc
uniprot id: W5MV95
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

7918:LOC102687231
gene id: 7918:LOC102687231
uniprot id: W5MWN9
names: Subcellular Location Annotation
messages: Membrane

7918:srp54
gene id: 7918:srp54
uniprot id: W5MT20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus speckle
messages: The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.
messages: The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

7918:LOC102693553
gene id: 7918:LOC102693553
uniprot id: W5N907
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

7918:itga8
gene id: 7918:itga8
uniprot id: W5MWR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

7918:pde11a
gene id: 7918:pde11a
uniprot id: W5MJ12
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:LOC102695387
gene id: 7918:LOC102695387
uniprot id: W5MWC5
names: Subcellular Location Annotation
messages: Nucleus

7918:rspo3
gene id: 7918:rspo3
uniprot id: W5NIE1
names: Similarity
messages: Belongs to the R-spondin family.

7918:LOC102689304
gene id: 7918:LOC102689304
uniprot id: W5MW43
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.

7918:LOC102687524
gene id: 7918:LOC102687524
uniprot id: W5M3J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

7918:slc6a15
gene id: 7918:slc6a15
uniprot id: W5NHQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

7918:otx1
gene id: 7918:otx1
uniprot id: W5NGP5
names: Subcellular Location Annotation
messages: Nucleus

7918:erap2
gene id: 7918:erap2
uniprot id: W5MGZ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

7918:cdadc1
gene id: 7918:cdadc1
uniprot id: W5MS78
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

7918:xkrx
gene id: 7918:xkrx
uniprot id: W5NDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

7918:tmem19
gene id: 7918:tmem19
uniprot id: W5NHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

7918:LOC102699080
gene id: 7918:LOC102699080
uniprot id: W5MYY1
names: Similarity
messages: Belongs to the sorting nexin family.

7918:arhgef7
gene id: 7918:arhgef7
uniprot id: W5MRT7
names: Subcellular Location Annotation
messages: lamellipodium

7918:chrm4
gene id: 7918:chrm4
uniprot id: W5ME74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

7918:sugct
gene id: 7918:sugct
uniprot id: W5N264
names: Similarity
messages: Belongs to the CoA-transferase III family.

7918:LOC102688763
gene id: 7918:LOC102688763
uniprot id: W5NCE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

7918:tpm4
gene id: 7918:tpm4
uniprot id: W5M718
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

7918:vldlr
gene id: 7918:vldlr
uniprot id: W5N449
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ldb1
gene id: 7918:ldb1
uniprot id: W5N4U5
names: Similarity
messages: Belongs to the LDB family.

7918:ntng1
gene id: 7918:ntng1
uniprot id: W5MMQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:serpine1
gene id: 7918:serpine1
uniprot id: W5N9L0
names: Similarity
messages: Belongs to the serpin family.

7918:LOC102687824
gene id: 7918:LOC102687824
uniprot id: W5NAM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:LOC102693381
gene id: 7918:LOC102693381
uniprot id: W5NPA8
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

7918:acvr2a
gene id: 7918:acvr2a
uniprot id: W5LZH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

7918:LOC102692330
gene id: 7918:LOC102692330
uniprot id: W5NNG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

7918:ncaph2
gene id: 7918:ncaph2
uniprot id: W5NFL0
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

7918:prpsap1
gene id: 7918:prpsap1
uniprot id: W5N7H4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

7918:camk4
gene id: 7918:camk4
uniprot id: W5MWD0
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:rhpn2
gene id: 7918:rhpn2
uniprot id: W5M105
names: Similarity
messages: Belongs to the RHPN family.

7918:tmco3
gene id: 7918:tmco3
uniprot id: W5MUN2
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102684229
gene id: 7918:LOC102684229
uniprot id: W5MRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

7918:dph2
gene id: 7918:dph2
uniprot id: W5M3U8
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

7918:dyrk2
gene id: 7918:dyrk2
uniprot id: W5NH23
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

7918:LOC102690206
gene id: 7918:LOC102690206
uniprot id: W5NI67
names: Similarity
messages: Belongs to the ARTD/PARP family.

7918:gpt2
gene id: 7918:gpt2
uniprot id: W5MDT5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

7918:gpr12
gene id: 7918:gpr12
uniprot id: W5NNT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:med13l
gene id: 7918:med13l
uniprot id: W5MLE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

7918:cpne7
gene id: 7918:cpne7
uniprot id: W5M947
names: Similarity
messages: Belongs to the copine family.

7918:cacnb1
gene id: 7918:cacnb1
uniprot id: W5N554
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

7918:eomes
gene id: 7918:eomes
uniprot id: W5M357
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

7918:dlgap3
gene id: 7918:dlgap3
uniprot id: W5M0X0
names: Similarity
messages: Belongs to the SAPAP family.

7918:myt1
gene id: 7918:myt1
uniprot id: W5MD53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

7918:lztfl1
gene id: 7918:lztfl1
uniprot id: W5N2B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

7918:kcnd3
gene id: 7918:kcnd3
uniprot id: W5MWD5
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

7918:ppargc1a
gene id: 7918:ppargc1a
uniprot id: W5N3J8
names: Subcellular Location Annotation
messages: PML body

7918:serbp1
gene id: 7918:serbp1
uniprot id: W5MJP7
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

7918:tspan8
gene id: 7918:tspan8
uniprot id: W5NHA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:ergic1
gene id: 7918:ergic1
uniprot id: W5N2D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

7918:LOC102688902
gene id: 7918:LOC102688902
uniprot id: W5N225
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

7918:cnih1
gene id: 7918:cnih1
uniprot id: W5N1K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

7918:itgb8
gene id: 7918:itgb8
uniprot id: W5N095
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

7918:atp2b3
gene id: 7918:atp2b3
uniprot id: W5NET1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:LOC107078266
gene id: 7918:LOC107078266
uniprot id: W5N216
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

7918:hcn1
gene id: 7918:hcn1
uniprot id: W5N255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

7918:syf2
gene id: 7918:syf2
uniprot id: W5M4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

7918:cav2
gene id: 7918:cav2
uniprot id: W5NEZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

7918:snrpa1
gene id: 7918:snrpa1
uniprot id: W5N9P6
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

7918:LOC102691779
gene id: 7918:LOC102691779
uniprot id: W5ND29
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:LOC102694949
gene id: 7918:LOC102694949
uniprot id: W5NKG4
names: Similarity
messages: Belongs to the aldo/keto reductase family.

7918:ccdc93
gene id: 7918:ccdc93
uniprot id: W5M5Q1
names: Similarity
messages: Belongs to the CCDC93 family.

7918:cplx1
gene id: 7918:cplx1
uniprot id: W5MTP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

7918:dhx8
gene id: 7918:dhx8
uniprot id: W5N2U1
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102691853
gene id: 7918:LOC102691853
uniprot id: W5NN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

7918:slc39a6
gene id: 7918:slc39a6
uniprot id: W5N520
names: Subcellular Location Annotation
messages: Membrane

7918:slc39a3
gene id: 7918:slc39a3
uniprot id: W5LW87
names: Subcellular Location Annotation
messages: Membrane

7918:tspan17
gene id: 7918:tspan17
uniprot id: W5N1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:myc
gene id: 7918:myc
uniprot id: W5MZP0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

7918:kif1c
gene id: 7918:kif1c
uniprot id: W5N8E0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:LOC102696091
gene id: 7918:LOC102696091
uniprot id: W5M3J9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

7918:stat4
gene id: 7918:stat4
uniprot id: W5MV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

7918:ube2a
gene id: 7918:ube2a
uniprot id: W5NDN3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:rbm8a
gene id: 7918:rbm8a
uniprot id: W5MRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBM8A family.
messages: Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
messages: Cytoplasm
messages: Heterodimer with MAGOH. Part of the mRNA splicing-dependent exon junction complex (EJC) complex; the core complex contains CASC3, EIF4A3, MAGOH and RBM8A.
messages: Nucleus
messages: Nucleus speckle

7918:qpctl
gene id: 7918:qpctl
uniprot id: W5NCA8
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

7918:grk4
gene id: 7918:grk4
uniprot id: W5MWQ6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

7918:gabbr2
gene id: 7918:gabbr2
uniprot id: W5MJZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:dmgdh
gene id: 7918:dmgdh
uniprot id: W5MFB4
names: Similarity
messages: Belongs to the GcvT family.

7918:gck
gene id: 7918:gck
uniprot id: W5NDG7
names: Similarity
messages: Belongs to the hexokinase family.

7918:LOC102685022
gene id: 7918:LOC102685022
uniprot id: W5LZU7
names: Similarity
messages: Belongs to the phospholipase D family.

7918:rpl18a
gene id: 7918:rpl18a
uniprot id: W5NID3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

7918:slc26a9
gene id: 7918:slc26a9
uniprot id: W5MXZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Ion transporter that can act both as an ion channel and anion exchanger. Mainly acts as a chloride channel, which mediate uncoupled chloride anion transport in an alternate-access mechanism where a saturable binding site is alternately exposed to either one or the other side of the membrane. Also acts as a DIDS- and thiosulfate- sensitive anion exchanger the exchange of chloride for bicarbonate ions across the cell membrane.
messages: Membrane

7918:fam221a
gene id: 7918:fam221a
uniprot id: W5N0Y5
names: Similarity
messages: Belongs to the FAM221 family.

7918:pde1b
gene id: 7918:pde1b
uniprot id: W5MCE7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:fzd4
gene id: 7918:fzd4
uniprot id: W5MJP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

7918:pign
gene id: 7918:pign
uniprot id: W5N7I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:LOC102693253
gene id: 7918:LOC102693253
uniprot id: W5M1E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

7918:tmem192
gene id: 7918:tmem192
uniprot id: W5MML2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

7918:ndufs4
gene id: 7918:ndufs4
uniprot id: W5MJ57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

7918:dok5
gene id: 7918:dok5
uniprot id: W5M3P3
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

7918:pole2
gene id: 7918:pole2
uniprot id: W5N091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

7918:atg16l1
gene id: 7918:atg16l1
uniprot id: W5MSH2
uniprot id: W5MSI4
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

7918:ltn1
gene id: 7918:ltn1
uniprot id: W5MRG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

7918:wbscr22
gene id: 7918:wbscr22
uniprot id: W5M002
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

7918:hoxb13
gene id: 7918:hoxb13
uniprot id: W5N7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

7918:esco2
gene id: 7918:esco2
uniprot id: W5NFT4
names: Subcellular Location Annotation
messages: Nucleus

7918:cntnap1
gene id: 7918:cntnap1
uniprot id: W5N3S8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: paranodal septate junction

7918:emc3
gene id: 7918:emc3
uniprot id: W5MXN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

7918:sap18
gene id: 7918:sap18
uniprot id: W5MYE8
names: Function
names: Similarity
messages: Belongs to the SAP18 family.
messages: Involved in the tethering of the SIN3 complex to core histone proteins.

7918:cdkal1
gene id: 7918:cdkal1
uniprot id: W5MR70
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

7918:tmem70
gene id: 7918:tmem70
uniprot id: W5M7J1
names: Similarity
messages: Belongs to the TMEM70 family.

7918:clspn
gene id: 7918:clspn
uniprot id: W5LX44
names: Subcellular Location Annotation
messages: Nucleus

7918:sh3yl1
gene id: 7918:sh3yl1
uniprot id: W5NL03
names: Similarity
messages: Belongs to the SH3YL1 family.

7918:LOC102685633
gene id: 7918:LOC102685633
uniprot id: W5MBS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:triqk
gene id: 7918:triqk
uniprot id: W5MVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:adgrl1
gene id: 7918:adgrl1
uniprot id: W5MQU7
names: Subcellular Location Annotation
messages: Membrane

7918:pigb
gene id: 7918:pigb
uniprot id: W5N7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:lig3
gene id: 7918:lig3
uniprot id: W5M261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

7918:vsig1
gene id: 7918:vsig1
uniprot id: W5N8J8
names: Subcellular Location Annotation
messages: Membrane

7918:trmu
gene id: 7918:trmu
uniprot id: W5NGN9
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

7918:LOC102692662
gene id: 7918:LOC102692662
uniprot id: W5NKI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

7918:chst8
gene id: 7918:chst8
uniprot id: W5M1J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:LOC102694403
gene id: 7918:LOC102694403
uniprot id: W5MYJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:il13ra2
gene id: 7918:il13ra2
uniprot id: W5N846
names: Subcellular Location Annotation
messages: Membrane

7918:LOC107076647
gene id: 7918:LOC107076647
uniprot id: W5NM14
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

7918:drc1
gene id: 7918:drc1
uniprot id: W5NH35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC1 family.
messages: cilium axoneme
messages: flagellum axoneme

7918:LOC102696549
gene id: 7918:LOC102696549
uniprot id: W5NMX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:LOC102698275
gene id: 7918:LOC102698275
uniprot id: W5NNY8
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

7918:LOC107079272
gene id: 7918:LOC107079272
uniprot id: W5N6F1
names: Subcellular Location Annotation
messages: Secreted

7918:LOC102689111
gene id: 7918:LOC102689111
uniprot id: W5N5A2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

7918:kcnk1
gene id: 7918:kcnk1
uniprot id: W5NH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

7918:acmsd
gene id: 7918:acmsd
uniprot id: W5M120
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

7918:ngb
gene id: 7918:ngb
uniprot id: W5MYS7
names: Similarity
messages: Belongs to the globin family.

7918:dyrk1a
gene id: 7918:dyrk1a
uniprot id: W5MC46
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

7918:tceb1
gene id: 7918:tceb1
uniprot id: W5M7M3
names: Similarity
messages: Belongs to the SKP1 family.

7918:memo1
gene id: 7918:memo1
uniprot id: W5NG80
names: Similarity
messages: Belongs to the MEMO1 family.

7918:ror2
gene id: 7918:ror2
uniprot id: W5MNN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:ccm2l
gene id: 7918:ccm2l
uniprot id: W5MDU1
names: Similarity
messages: Belongs to the CCM2 family.

7918:LOC102689161
gene id: 7918:LOC102689161
uniprot id: W5NN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

7918:LOC102696009
gene id: 7918:LOC102696009
uniprot id: W5M1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

7918:LOC102684189
gene id: 7918:LOC102684189
uniprot id: W5N0J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

7918:cflar
gene id: 7918:cflar
uniprot id: W5MUJ7
names: Similarity
messages: Belongs to the peptidase C14A family.

7918:LOC102687440
gene id: 7918:LOC102687440
uniprot id: W5M2H1
names: Similarity
messages: Belongs to the BRINP family.

7918:cenpl
gene id: 7918:cenpl
uniprot id: W5MS61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

7918:calb2
gene id: 7918:calb2
uniprot id: W5MHJ2
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

7918:gatm
gene id: 7918:gatm
uniprot id: W5N5T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development.
messages: Homodimer.
messages: Mitochondrion inner membrane

7918:prkg2
gene id: 7918:prkg2
uniprot id: W5MJT9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

7918:kiaa1324l
gene id: 7918:kiaa1324l
uniprot id: W5NJ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

7918:clg21h9orf114
gene id: 7918:clg21h9orf114
uniprot id: W5M9A0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily.

7918:LOC102696439
gene id: 7918:LOC102696439
uniprot id: W5NNR4
names: Similarity
messages: Belongs to the nanos family.

7918:sgcd
gene id: 7918:sgcd
uniprot id: W5N3Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

7918:clps
gene id: 7918:clps
uniprot id: W5MZ84
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

7918:polr2c
gene id: 7918:polr2c
uniprot id: W5M5Z7
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

7918:hs3st6
gene id: 7918:hs3st6
uniprot id: W5MCG8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

7918:tmem131
gene id: 7918:tmem131
uniprot id: W5MPI0
names: Similarity
messages: Belongs to the TMEM131 family.

7918:pld1
gene id: 7918:pld1
uniprot id: W5MKU5
names: Similarity
messages: Belongs to the phospholipase D family.

7918:sbno2
gene id: 7918:sbno2
uniprot id: W5MB13
names: Similarity
messages: Belongs to the SBNO family.

7918:pigf
gene id: 7918:pigf
uniprot id: W5NHQ4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:isca1
gene id: 7918:isca1
uniprot id: W5M3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

7918:pigl
gene id: 7918:pigl
uniprot id: W5M6Y2
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

7918:lamc2
gene id: 7918:lamc2
uniprot id: W5M205
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

7918:rnft1
gene id: 7918:rnft1
uniprot id: W5M836
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102690085
gene id: 7918:LOC102690085
uniprot id: W5MWF8
names: Subcellular Location Annotation
messages: Membrane

7918:ptp4a1
gene id: 7918:ptp4a1
uniprot id: W5NK84
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

7918:chmp1b
gene id: 7918:chmp1b
uniprot id: W5NCV5
names: Similarity
messages: Belongs to the SNF7 family.

7918:LOC102693428
gene id: 7918:LOC102693428
uniprot id: W5NLT6
names: Similarity
messages: Belongs to the syntaxin family.

7918:LOC102685244
gene id: 7918:LOC102685244
uniprot id: W5NP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

7918:slc16a5
gene id: 7918:slc16a5
uniprot id: W5MXT5
names: Subcellular Location Annotation
messages: Membrane

7918:cacng5
gene id: 7918:cacng5
uniprot id: W5N849
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

7918:LOC102697930
gene id: 7918:LOC102697930
uniprot id: W5M797
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

7918:scrn3
gene id: 7918:scrn3
uniprot id: W5MKL3
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

7918:pabpc4
gene id: 7918:pabpc4
uniprot id: W5M1D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

7918:fam161a
gene id: 7918:fam161a
uniprot id: W5NGR4
names: Similarity
messages: Belongs to the FAM161 family.

7918:hnrnpk
gene id: 7918:hnrnpk
uniprot id: W5M2Q6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm

7918:meis1
gene id: 7918:meis1
uniprot id: W5NGI1
uniprot id: W5NGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

7918:fgf22
gene id: 7918:fgf22
uniprot id: W5MD52
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

7918:cldn18
gene id: 7918:cldn18
uniprot id: W5MGH9
uniprot id: W5MGK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

7918:LOC102698903
gene id: 7918:LOC102698903
uniprot id: W5N323
names: Function
names: Subcellular Location Annotation
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
messages: Mitochondrion inner membrane

7918:LOC102685329
gene id: 7918:LOC102685329
uniprot id: W5NF03
names: Similarity
messages: Belongs to the peptidase M14 family.

7918:galnt3
gene id: 7918:galnt3
uniprot id: W5MNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:nceh1
gene id: 7918:nceh1
uniprot id: W5ML46
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

7918:dnmt3a
gene id: 7918:dnmt3a
uniprot id: W5NHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

7918:gfra4
gene id: 7918:gfra4
uniprot id: W5LY95
names: Similarity
messages: Belongs to the GDNFR family.

7918:LOC102689506
gene id: 7918:LOC102689506
uniprot id: W5NCQ7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

7918:fam163b
gene id: 7918:fam163b
uniprot id: W5M422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

7918:cryl1
gene id: 7918:cryl1
uniprot id: W5MY58
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

7918:eml4
gene id: 7918:eml4
uniprot id: W5NI87
names: Similarity
messages: Belongs to the WD repeat EMAP family.

7918:xpo1
gene id: 7918:xpo1
uniprot id: W5NGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

7918:faah
gene id: 7918:faah
uniprot id: W5M8W4
names: Similarity
messages: Belongs to the amidase family.

7918:syn3
gene id: 7918:syn3
uniprot id: W5NI71
names: Similarity
messages: Belongs to the synapsin family.

7918:fnip2
gene id: 7918:fnip2
uniprot id: W5MN16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

7918:sumo2
gene id: 7918:sumo2
uniprot id: W5N757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

7918:letm1
gene id: 7918:letm1
uniprot id: W5MJE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

7918:cdk18
gene id: 7918:cdk18
uniprot id: W5N1Q9
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:olah
gene id: 7918:olah
uniprot id: W5MWL0
names: Similarity
messages: Belongs to the thioesterase family.

7918:six5
gene id: 7918:six5
uniprot id: W5NCB5
names: Subcellular Location Annotation
messages: Nucleus

7918:p2ry2
gene id: 7918:p2ry2
uniprot id: W5NNV9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:LOC102684990
gene id: 7918:LOC102684990
uniprot id: W5MG70
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

7918:faxc
gene id: 7918:faxc
uniprot id: W5NKG9
names: Similarity
messages: Belongs to the FAX family.

7918:pou3f4
gene id: 7918:pou3f4
uniprot id: W5NLT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

7918:vhl
gene id: 7918:vhl
uniprot id: W5MZ44
names: Similarity
messages: Belongs to the VHL family.

7918:LOC102689307
gene id: 7918:LOC102689307
uniprot id: W5MGB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:tmed3
gene id: 7918:tmed3
uniprot id: W5NAI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

7918:cdkn3
gene id: 7918:cdkn3
uniprot id: W5N1L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: Early endosome
messages: Endosome
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

7918:LOC102698502
gene id: 7918:LOC102698502
uniprot id: W5MCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:dgkk
gene id: 7918:dgkk
uniprot id: W5NAG8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

7918:frrs1
gene id: 7918:frrs1
uniprot id: W5LYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

7918:mapk8
gene id: 7918:mapk8
uniprot id: W5M8N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

7918:ywhae
gene id: 7918:ywhae
uniprot id: W5MJQ4
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

7918:gabrg1
gene id: 7918:gabrg1
uniprot id: W5N3P6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:laptm4a
gene id: 7918:laptm4a
uniprot id: W5NKU2
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

7918:orc4
gene id: 7918:orc4
uniprot id: W5LZL4
uniprot id: W5LZN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

7918:LOC102698868
gene id: 7918:LOC102698868
uniprot id: W5NE29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

7918:LOC102688650
gene id: 7918:LOC102688650
uniprot id: W5MC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

7918:cep63
gene id: 7918:cep63
uniprot id: W5MD58
names: Similarity
messages: Belongs to the CEP63 family.

7918:ndufv3
gene id: 7918:ndufv3
uniprot id: W5M8D3
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

7918:sap30l
gene id: 7918:sap30l
uniprot id: W5N3V2
names: Similarity
messages: Belongs to the SAP30 family.

7918:asun
gene id: 7918:asun
uniprot id: W5NDW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

7918:LOC102690237
gene id: 7918:LOC102690237
uniprot id: W5M985
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:slc24a2
gene id: 7918:slc24a2
uniprot id: W5MYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

7918:gnpda1
gene id: 7918:gnpda1
uniprot id: W5MX43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

7918:tm2d3
gene id: 7918:tm2d3
uniprot id: W5NBF7
names: Subcellular Location Annotation
messages: Membrane

7918:pter
gene id: 7918:pter
uniprot id: W5MWR9
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:mctp2
gene id: 7918:mctp2
uniprot id: W5NAS4
names: Subcellular Location Annotation
messages: Membrane

7918:pik3r2
gene id: 7918:pik3r2
uniprot id: W5M050
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

7918:chst7
gene id: 7918:chst7
uniprot id: W5NMP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

7918:sf3a3
gene id: 7918:sf3a3
uniprot id: W5M667
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3A3 family.
messages: Nucleus

7918:atp2b2
gene id: 7918:atp2b2
uniprot id: W5N928
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:cnn3
gene id: 7918:cnn3
uniprot id: W5MNF1
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

7918:stpg1
gene id: 7918:stpg1
uniprot id: W5M4S9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:edem1
gene id: 7918:edem1
uniprot id: W5MYH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

7918:LOC102691889
gene id: 7918:LOC102691889
uniprot id: W5LXS3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:slc25a10
gene id: 7918:slc25a10
uniprot id: W5N965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:mdfic
gene id: 7918:mdfic
uniprot id: W5NG66
names: Similarity
messages: Belongs to the MDFI family.

7918:sf3b4
gene id: 7918:sf3b4
uniprot id: W5MRL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

7918:mrpl30
gene id: 7918:mrpl30
uniprot id: W5LZW4
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

7918:LOC107076841
gene id: 7918:LOC107076841
uniprot id: W5N0B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

7918:npm3
gene id: 7918:npm3
uniprot id: W5LXC6
names: Similarity
messages: Belongs to the nucleoplasmin family.

7918:LOC107078546
gene id: 7918:LOC107078546
uniprot id: W5MWF5
names: Similarity
messages: Belongs to the FMO family.

7918:tmem55b
gene id: 7918:tmem55b
uniprot id: W5LX78
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

7918:LOC102686539
gene id: 7918:LOC102686539
uniprot id: W5N2A3
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

7918:ctns
gene id: 7918:ctns
uniprot id: W5M6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

7918:ap1b1
gene id: 7918:ap1b1
uniprot id: W5MN65
uniprot id: W5MN72
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

7918:LOC102682294
gene id: 7918:LOC102682294
uniprot id: W5NLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:hmces
gene id: 7918:hmces
uniprot id: W5NB99
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

7918:msh3
gene id: 7918:msh3
uniprot id: W5MD68
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

7918:mrps18c
gene id: 7918:mrps18c
uniprot id: W5N2P8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS18 family.

7918:LOC102692800
gene id: 7918:LOC102692800
uniprot id: W5MZL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

7918:grp
gene id: 7918:grp
uniprot id: W5N1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

7918:sharpin
gene id: 7918:sharpin
uniprot id: W5MR49
names: Similarity
messages: Belongs to the RBR family.

7918:palmd
gene id: 7918:palmd
uniprot id: W5LY92
names: Similarity
messages: Belongs to the paralemmin family.

7918:marveld3
gene id: 7918:marveld3
uniprot id: W5M9U5
names: Subcellular Location Annotation
messages: Membrane

7918:LOC107075820
gene id: 7918:LOC107075820
uniprot id: W5MER4
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

7918:clg1h14orf169
gene id: 7918:clg1h14orf169
uniprot id: W5NFB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Nucleus
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.

7918:bves
gene id: 7918:bves
uniprot id: W5NIG5
names: Similarity
messages: Belongs to the popeye family.

7918:purg
gene id: 7918:purg
uniprot id: W5NLY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

7918:b3gnt7
gene id: 7918:b3gnt7
uniprot id: W5MBR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:hck
gene id: 7918:hck
uniprot id: W5MFD7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:smpd3
gene id: 7918:smpd3
uniprot id: W5M6U4
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

7918:tmem150a
gene id: 7918:tmem150a
uniprot id: W5NE39
names: Subcellular Location Annotation
messages: Membrane

7918:grb2
gene id: 7918:grb2
uniprot id: W5N6Z2
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

7918:fam171a1
gene id: 7918:fam171a1
uniprot id: W5MWN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

7918:lamc1
gene id: 7918:lamc1
uniprot id: W5M265
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

7918:acer3
gene id: 7918:acer3
uniprot id: W5LYJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:gcg
gene id: 7918:gcg
uniprot id: W5MPN6
names: Similarity
messages: Belongs to the glucagon family.

7918:tubd1
gene id: 7918:tubd1
uniprot id: W5M887
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

7918:LOC102683954
gene id: 7918:LOC102683954
uniprot id: W5MEL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

7918:LOC102694358
gene id: 7918:LOC102694358
uniprot id: W5NDQ4
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

7918:magi3
gene id: 7918:magi3
uniprot id: W5MYN9
names: Subcellular Location Annotation
messages: Membrane

7918:timm9
gene id: 7918:timm9
uniprot id: W5MSP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

7918:uvssa
gene id: 7918:uvssa
uniprot id: W5MYM5
names: Similarity
messages: Belongs to the UVSSA family.

7918:vdac1
gene id: 7918:vdac1
uniprot id: W5MW14
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

7918:LOC102698732
gene id: 7918:LOC102698732
uniprot id: W5NJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

7918:tbl3
gene id: 7918:tbl3
uniprot id: W5MQX2
names: Subcellular Location Annotation
messages: nucleolus

7918:dhps
gene id: 7918:dhps
uniprot id: W5MG86
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

7918:plin2
gene id: 7918:plin2
uniprot id: W5N0Y3
names: Similarity
messages: Belongs to the perilipin family.

7918:adamts9
gene id: 7918:adamts9
uniprot id: W5MW40
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:epha10
gene id: 7918:epha10
uniprot id: W5MFW3
names: Subcellular Location Annotation
messages: Membrane

7918:ppm1g
gene id: 7918:ppm1g
uniprot id: W5NEL6
names: Similarity
messages: Belongs to the PP2C family.

7918:endog
gene id: 7918:endog
uniprot id: W5M9B9
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

7918:fbln2
gene id: 7918:fbln2
uniprot id: W5N9J8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:dpm2
gene id: 7918:dpm2
uniprot id: W5MGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

7918:opa3
gene id: 7918:opa3
uniprot id: W5NA68
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

7918:LOC102694859
gene id: 7918:LOC102694859
uniprot id: W5N490
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102685666
gene id: 7918:LOC102685666
uniprot id: W5NNM3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:clg4h4orf48
gene id: 7918:clg4h4orf48
uniprot id: W5M2F6
names: Subcellular Location Annotation
messages: Secreted

7918:tmem8b
gene id: 7918:tmem8b
uniprot id: W5N040
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

7918:bmp15
gene id: 7918:bmp15
uniprot id: W5NAJ0
names: Similarity
messages: Belongs to the TGF-beta family.

7918:LOC102687114
gene id: 7918:LOC102687114
uniprot id: W5MMU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

7918:LOC102689166
gene id: 7918:LOC102689166
uniprot id: W5NCH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

7918:nip7
gene id: 7918:nip7
uniprot id: W5LZK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

7918:sts
gene id: 7918:sts
uniprot id: W5MVK6
names: Similarity
messages: Belongs to the sulfatase family.

7918:lama3
gene id: 7918:lama3
uniprot id: W5LZT2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

7918:elf1
gene id: 7918:elf1
uniprot id: W5MDJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:crtc3
gene id: 7918:crtc3
uniprot id: W5N9Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

7918:fam3d
gene id: 7918:fam3d
uniprot id: W5MWT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

7918:zfyve28
gene id: 7918:zfyve28
uniprot id: W5MIY5
names: Similarity
messages: Belongs to the lst-2 family.

7918:LOC102682539
gene id: 7918:LOC102682539
uniprot id: W5NLM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:cdc25b
gene id: 7918:cdc25b
uniprot id: W5LYK4
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

7918:prkcz
gene id: 7918:prkcz
uniprot id: W5MEZ0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

7918:gmds
gene id: 7918:gmds
uniprot id: W5N5T0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

7918:kcnh2
gene id: 7918:kcnh2
uniprot id: W5MQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

7918:irf8
gene id: 7918:irf8
uniprot id: W5LYD7
names: Subcellular Location Annotation
messages: Nucleus

7918:fgf12
gene id: 7918:fgf12
uniprot id: W5MSR9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

7918:tspan2
gene id: 7918:tspan2
uniprot id: W5MX63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:gpr62
gene id: 7918:gpr62
uniprot id: W5NNY9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:ahsa1
gene id: 7918:ahsa1
uniprot id: W5N6C5
names: Similarity
messages: Belongs to the AHA1 family.

7918:kcnq2
gene id: 7918:kcnq2
uniprot id: W5M0F6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:phactr2
gene id: 7918:phactr2
uniprot id: W5NEE7
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

7918:spdef
gene id: 7918:spdef
uniprot id: W5MUZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:ca10
gene id: 7918:ca10
uniprot id: W5MYY9
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

7918:dfnb59
gene id: 7918:dfnb59
uniprot id: W5MGQ6
names: Similarity
messages: Belongs to the gasdermin family.

7918:usp49
gene id: 7918:usp49
uniprot id: W5N4K9
names: Similarity
messages: Belongs to the peptidase C19 family.

7918:LOC102691763
gene id: 7918:LOC102691763
uniprot id: W5M783
names: Similarity
messages: Belongs to the dysbindin family.

7918:kcnq5
gene id: 7918:kcnq5
uniprot id: W5NH30
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:trmt1l
gene id: 7918:trmt1l
uniprot id: W5M106
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

7918:slc8b1
gene id: 7918:slc8b1
uniprot id: W5MPF1
names: Subcellular Location Annotation
messages: Membrane

7918:lamb2
gene id: 7918:lamb2
uniprot id: W5N6D6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

7918:galnt18
gene id: 7918:galnt18
uniprot id: W5M8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:tfe3
gene id: 7918:tfe3
uniprot id: W5NBS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

7918:ncln
gene id: 7918:ncln
uniprot id: W5M914
names: Function
names: Similarity
messages: Belongs to the nicastrin family.
messages: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.

7918:LOC102694198
gene id: 7918:LOC102694198
uniprot id: W5MZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMN family.
messages: Cajal body
messages: Perikaryon
messages: Z line
messages: gem
messages: neuron projection

7918:LOC102695950
gene id: 7918:LOC102695950
uniprot id: W5MI79
names: Similarity
messages: Belongs to the FXYD family.

7918:cenpu
gene id: 7918:cenpu
uniprot id: W5N8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

7918:LOC102695961
gene id: 7918:LOC102695961
uniprot id: W5MA09
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

7918:ppp4r3a
gene id: 7918:ppp4r3a
uniprot id: W5N6K1
names: Similarity
messages: Belongs to the SMEK family.

7918:atp8a2
gene id: 7918:atp8a2
uniprot id: W5M952
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

7918:sec63
gene id: 7918:sec63
uniprot id: W5NIP1
names: Subcellular Location Annotation
messages: Membrane

7918:si
gene id: 7918:si
uniprot id: W5M708
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:gata3
gene id: 7918:gata3
uniprot id: W5NF99
names: Subcellular Location Annotation
messages: Nucleus

7918:lrrc8d
gene id: 7918:lrrc8d
uniprot id: W5NMI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

7918:hdhd2
gene id: 7918:hdhd2
uniprot id: W5N3Q5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

7918:slc25a28
gene id: 7918:slc25a28
uniprot id: W5MRI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:apoh
gene id: 7918:apoh
uniprot id: W5N889
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:LOC102689245
gene id: 7918:LOC102689245
uniprot id: W5MKW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

7918:efemp2
gene id: 7918:efemp2
uniprot id: W5LXD3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102692773
gene id: 7918:LOC102692773
uniprot id: W5MXJ7
names: Similarity
messages: Belongs to the RCAN family.

7918:irx6
gene id: 7918:irx6
uniprot id: W5MJM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

7918:psma6
gene id: 7918:psma6
uniprot id: W5MS18
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

7918:cpsf4
gene id: 7918:cpsf4
uniprot id: W5MBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

7918:nefl
gene id: 7918:nefl
uniprot id: W5NF82
names: Similarity
messages: Belongs to the intermediate filament family.

7918:tmcc1
gene id: 7918:tmcc1
uniprot id: W5N5X7
names: Similarity
messages: Belongs to the TEX28 family.

7918:LOC102695073
gene id: 7918:LOC102695073
uniprot id: W5MUN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

7918:ccdc65
gene id: 7918:ccdc65
uniprot id: W5MM06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC1 family.
messages: cilium axoneme
messages: flagellum axoneme

7918:hsp90aa1
gene id: 7918:hsp90aa1
uniprot id: W5N0J2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

7918:hmgn3
gene id: 7918:hmgn3
uniprot id: W5NHB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

7918:fat3
gene id: 7918:fat3
uniprot id: W5MK81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:atp10b
gene id: 7918:atp10b
uniprot id: W5MXP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

7918:rarg
gene id: 7918:rarg
uniprot id: W5MGN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

7918:wnt7b
gene id: 7918:wnt7b
uniprot id: W5NK83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:eml2
gene id: 7918:eml2
uniprot id: W5NC62
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

7918:jak3
gene id: 7918:jak3
uniprot id: W5M4D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

7918:adra2c
gene id: 7918:adra2c
uniprot id: W5NND0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:ruvbl1
gene id: 7918:ruvbl1
uniprot id: W5NB75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

7918:hoxd3
gene id: 7918:hoxd3
uniprot id: W5MJG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

7918:trh
gene id: 7918:trh
uniprot id: W5MZE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Secreted

7918:dusp9
gene id: 7918:dusp9
uniprot id: W5NER1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

7918:trpc4
gene id: 7918:trpc4
uniprot id: W5MPU6
names: Subcellular Location Annotation
messages: Membrane

7918:grem2
gene id: 7918:grem2
uniprot id: W5NLG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

7918:rfc4
gene id: 7918:rfc4
uniprot id: W5LXX2
names: Similarity
messages: Belongs to the activator 1 small subunits family.

7918:cacng3
gene id: 7918:cacng3
uniprot id: W5MDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

7918:cks2
gene id: 7918:cks2
uniprot id: W5N1B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

7918:pdgfrl
gene id: 7918:pdgfrl
uniprot id: W5N938
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.

7918:LOC102698680
gene id: 7918:LOC102698680
uniprot id: W5NA06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

7918:sag
gene id: 7918:sag
uniprot id: W5MSF3
names: Similarity
messages: Belongs to the arrestin family.

7918:pkp3
gene id: 7918:pkp3
uniprot id: W5MI57
names: Similarity
messages: Belongs to the beta-catenin family.

7918:LOC102696733
gene id: 7918:LOC102696733
uniprot id: W5NNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

7918:cmbl
gene id: 7918:cmbl
uniprot id: W5N7U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

7918:anapc5
gene id: 7918:anapc5
uniprot id: W5MCJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

7918:prkcd
gene id: 7918:prkcd
uniprot id: W5NB04
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.
messages: Cytoplasm
messages: Interacts with PDPK1 (via N-terminal region), RAD9A, CDCP1, MUC1 and VASP.
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: perinuclear region

7918:dnah9
gene id: 7918:dnah9
uniprot id: W5N2W8
names: Similarity
messages: Belongs to the dynein heavy chain family.

7918:nadk2
gene id: 7918:nadk2
uniprot id: W5N4X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

7918:hoxb5
gene id: 7918:hoxb5
uniprot id: W5N7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

7918:lin54
gene id: 7918:lin54
uniprot id: W5MXH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

7918:ppp1r1c
gene id: 7918:ppp1r1c
uniprot id: W5MHU3
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

7918:nlk
gene id: 7918:nlk
uniprot id: W5MEN2
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

7918:bok
gene id: 7918:bok
uniprot id: W5MHB6
names: Similarity
messages: Belongs to the Bcl-2 family.

7918:mthfd1
gene id: 7918:mthfd1
uniprot id: W5N5G8
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

7918:fabp7
gene id: 7918:fabp7
uniprot id: W5NL36
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

7918:wt1
gene id: 7918:wt1
uniprot id: W5MAL8
uniprot id: W5MAN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

7918:LOC102683569
gene id: 7918:LOC102683569
uniprot id: W5NN80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

7918:ap4m1
gene id: 7918:ap4m1
uniprot id: W5N669
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal.
messages: Early endosome
messages: trans-Golgi network membrane

7918:mnd1
gene id: 7918:mnd1
uniprot id: W5MPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

7918:scarb2
gene id: 7918:scarb2
uniprot id: W5M8G7
names: Similarity
messages: Belongs to the CD36 family.

7918:dclk1
gene id: 7918:dclk1
uniprot id: W5MPA6
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

7918:syndig1l
gene id: 7918:syndig1l
uniprot id: W5MY67
names: Similarity
messages: Belongs to the CD225/Dispanin family.

7918:march11
gene id: 7918:march11
uniprot id: W5N4K5
names: Subcellular Location Annotation
messages: Membrane

7918:nrde2
gene id: 7918:nrde2
uniprot id: W5MRL3
names: Similarity
messages: Belongs to the NRDE2 family.

7918:mdk
gene id: 7918:mdk
uniprot id: W5MEA0
names: Similarity
messages: Belongs to the pleiotrophin family.

7918:LOC102685669
gene id: 7918:LOC102685669
uniprot id: W5MCD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

7918:fam13b
gene id: 7918:fam13b
uniprot id: W5N384
names: Similarity
messages: Belongs to the FAM13 family.

7918:psme3
gene id: 7918:psme3
uniprot id: W5N2X4
names: Similarity
messages: Belongs to the PA28 family.

7918:LOC102690714
gene id: 7918:LOC102690714
uniprot id: W5M1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

7918:chrm5
gene id: 7918:chrm5
uniprot id: W5NMF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

7918:gstcd
gene id: 7918:gstcd
uniprot id: W5N4J2
names: Similarity
messages: Belongs to the GSTCD family.

7918:dhdds
gene id: 7918:dhdds
uniprot id: W5ME95
names: Similarity
messages: Belongs to the UPP synthase family.

7918:csmd3
gene id: 7918:csmd3
uniprot id: W5M6F4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:foxd2
gene id: 7918:foxd2
uniprot id: W5NMJ2
names: Subcellular Location Annotation
messages: Nucleus

7918:mylk
gene id: 7918:mylk
uniprot id: W5MEA4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

7918:isy1
gene id: 7918:isy1
uniprot id: W5N9D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

7918:mtmr7
gene id: 7918:mtmr7
uniprot id: W5N960
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

7918:LOC102685930
gene id: 7918:LOC102685930
uniprot id: W5MVQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

7918:c1qbp
gene id: 7918:c1qbp
uniprot id: W5M4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

7918:LOC102691803
gene id: 7918:LOC102691803
uniprot id: W5MVJ3
uniprot id: W5MVJ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

7918:rplp1
gene id: 7918:rplp1
uniprot id: W5MLX5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

7918:vma21
gene id: 7918:vma21
uniprot id: W5NBZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

7918:lsm5
gene id: 7918:lsm5
uniprot id: W5N5H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

7918:edem3
gene id: 7918:edem3
uniprot id: W5MW27
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

7918:ogfr
gene id: 7918:ogfr
uniprot id: W5M8B0
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

7918:rabac1
gene id: 7918:rabac1
uniprot id: W5MAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

7918:casd1
gene id: 7918:casd1
uniprot id: W5MY98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

7918:gpat3
gene id: 7918:gpat3
uniprot id: W5N2S0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

7918:edil3
gene id: 7918:edil3
uniprot id: W5M1M1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:tradd
gene id: 7918:tradd
uniprot id: W5MMP9
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

7918:LOC102692042
gene id: 7918:LOC102692042
uniprot id: W5M3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

7918:rag1
gene id: 7918:rag1
uniprot id: W5LZ93
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

7918:nr3c1
gene id: 7918:nr3c1
uniprot id: W5MWX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

7918:LOC102691805
gene id: 7918:LOC102691805
uniprot id: W5N0G1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:LOC102689444
gene id: 7918:LOC102689444
uniprot id: W5NEY8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

7918:plk4
gene id: 7918:plk4
uniprot id: W5MXN7
names: Subcellular Location Annotation
messages: centriole

7918:mrpl44
gene id: 7918:mrpl44
uniprot id: W5MTR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion

7918:LOC102685743
gene id: 7918:LOC102685743
uniprot id: W5NJY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

7918:lyve1
gene id: 7918:lyve1
uniprot id: W5M859
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:edem2
gene id: 7918:edem2
uniprot id: W5M9N8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

7918:ddx24
gene id: 7918:ddx24
uniprot id: W5N5V2
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

7918:clcn4
gene id: 7918:clcn4
uniprot id: W5MKE5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:slc25a27
gene id: 7918:slc25a27
uniprot id: W5NG03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:rho
gene id: 7918:rho
uniprot id: W5N608
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

7918:sgpl1
gene id: 7918:sgpl1
uniprot id: W5N0J9
names: Similarity
messages: Belongs to the group II decarboxylase family.

7918:dgkb
gene id: 7918:dgkb
uniprot id: W5MZM3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

7918:LOC107077586
gene id: 7918:LOC107077586
uniprot id: W5MRV5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:bre
gene id: 7918:bre
uniprot id: W5NKR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

7918:wapl
gene id: 7918:wapl
uniprot id: W5MP36
names: Similarity
messages: Belongs to the WAPL family.

7918:LOC102692047
gene id: 7918:LOC102692047
uniprot id: W5MP18
names: Similarity
messages: Belongs to the ATG8 family.

7918:mtnr1b
gene id: 7918:mtnr1b
uniprot id: W5MKE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

7918:rpl4
gene id: 7918:rpl4
uniprot id: W5N8Z5
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

7918:LOC102685361
gene id: 7918:LOC102685361
uniprot id: W5M6I5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:glmp
gene id: 7918:glmp
uniprot id: W5MK22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLMP family.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

7918:LOC102690077
gene id: 7918:LOC102690077
uniprot id: W5N4Z5
names: Similarity
messages: Belongs to the threonine aldolase family.

7918:tmc8
gene id: 7918:tmc8
uniprot id: W5N4L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

7918:clg23h16orf70
gene id: 7918:clg23h16orf70
uniprot id: W5MMI8
names: Similarity
messages: Belongs to the PHAF1 family.

7918:slc22a5
gene id: 7918:slc22a5
uniprot id: W5MWC2
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

7918:atrnl1
gene id: 7918:atrnl1
uniprot id: W5N5S1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102698426
gene id: 7918:LOC102698426
uniprot id: W5M810
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

7918:zc3hc1
gene id: 7918:zc3hc1
uniprot id: W5NG97
names: Subcellular Location Annotation
messages: Nucleus

7918:recql4
gene id: 7918:recql4
uniprot id: W5ML25
names: Subcellular Location Annotation
messages: Nucleus

7918:gbx2
gene id: 7918:gbx2
uniprot id: W5MBK2
names: Subcellular Location Annotation
messages: Nucleus

7918:cldn19
gene id: 7918:cldn19
uniprot id: W5LXZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:trub1
gene id: 7918:trub1
uniprot id: W5N5S7
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

7918:slc16a1
gene id: 7918:slc16a1
uniprot id: W5MW04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

7918:mrps36
gene id: 7918:mrps36
uniprot id: W5ML70
names: Subcellular Location Annotation
messages: Mitochondrion

7918:htr1d
gene id: 7918:htr1d
uniprot id: W5NP23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:stk33
gene id: 7918:stk33
uniprot id: W5M689
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:slc35f2
gene id: 7918:slc35f2
uniprot id: W5MIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

7918:ap2s1
gene id: 7918:ap2s1
uniprot id: W5NCH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

7918:edn3
gene id: 7918:edn3
uniprot id: W5M6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

7918:LOC102698785
gene id: 7918:LOC102698785
uniprot id: W5M160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

7918:dlgap1
gene id: 7918:dlgap1
uniprot id: W5M5Q3
names: Similarity
messages: Belongs to the SAPAP family.

7918:sec24d
gene id: 7918:sec24d
uniprot id: W5N473
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

7918:LOC102682520
gene id: 7918:LOC102682520
uniprot id: W5N2I5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

7918:LOC102696352
gene id: 7918:LOC102696352
uniprot id: W5MIF5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:trim32
gene id: 7918:trim32
uniprot id: W5NLE0
names: Similarity
messages: Belongs to the TRIM/RBCC family.

7918:rprd1a
gene id: 7918:rprd1a
uniprot id: W5M7E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

7918:ndst2
gene id: 7918:ndst2
uniprot id: W5N5A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

7918:rbm15
gene id: 7918:rbm15
uniprot id: W5NN34
names: Similarity
messages: Belongs to the RRM Spen family.

7918:gpx8
gene id: 7918:gpx8
uniprot id: W5M3N7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

7918:sncb
gene id: 7918:sncb
uniprot id: W5N1T7
names: Similarity
messages: Belongs to the synuclein family.

7918:map2k4
gene id: 7918:map2k4
uniprot id: W5N2R1
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:acsf2
gene id: 7918:acsf2
uniprot id: W5MXW1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

7918:LOC102688352
gene id: 7918:LOC102688352
uniprot id: W5NCF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

7918:pigw
gene id: 7918:pigw
uniprot id: W5NLM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

7918:odf2
gene id: 7918:odf2
uniprot id: W5MFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

7918:snrpd3
gene id: 7918:snrpd3
uniprot id: W5MJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

7918:col4a3bp
gene id: 7918:col4a3bp
uniprot id: W5MDW7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

7918:ier5
gene id: 7918:ier5
uniprot id: W5NMJ1
names: Similarity
messages: Belongs to the IER family.

7918:snupn
gene id: 7918:snupn
uniprot id: W5ND32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

7918:borcs8
gene id: 7918:borcs8
uniprot id: W5MBH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

7918:ftsj1
gene id: 7918:ftsj1
uniprot id: W5NFA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

7918:grik4
gene id: 7918:grik4
uniprot id: W5M1V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

7918:hnf1a
gene id: 7918:hnf1a
uniprot id: W5M4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

7918:LOC102683581
gene id: 7918:LOC102683581
uniprot id: W5N7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

7918:cdk6
gene id: 7918:cdk6
uniprot id: W5MXP0
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:LOC102689847
gene id: 7918:LOC102689847
uniprot id: W5NGT5
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

7918:glud1
gene id: 7918:glud1
uniprot id: W5N3V3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

7918:mpped2
gene id: 7918:mpped2
uniprot id: W5MB71
names: Similarity
messages: Belongs to the UPF0046 family.

7918:frzb
gene id: 7918:frzb
uniprot id: W5MI46
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

7918:pkm
gene id: 7918:pkm
uniprot id: W5NDB3
names: Similarity
messages: Belongs to the pyruvate kinase family.

7918:elmo3
gene id: 7918:elmo3
uniprot id: W5MGQ7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

7918:ube2k
gene id: 7918:ube2k
uniprot id: W5N5T9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:dner
gene id: 7918:dner
uniprot id: W5MNN0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:enpep
gene id: 7918:enpep
uniprot id: W5N1E1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

7918:dusp16
gene id: 7918:dusp16
uniprot id: W5NIB1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

7918:rdh13
gene id: 7918:rdh13
uniprot id: W5NFJ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:ndnf
gene id: 7918:ndnf
uniprot id: W5MUB1
names: Subcellular Location Annotation
messages: Secreted

7918:dck
gene id: 7918:dck
uniprot id: W5N0Q0
names: Similarity
messages: Belongs to the DCK/DGK family.

7918:akirin2
gene id: 7918:akirin2
uniprot id: W5NJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

7918:cdip1
gene id: 7918:cdip1
uniprot id: W5MLF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

7918:wasf1
gene id: 7918:wasf1
uniprot id: W5NKN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

7918:dnmt1
gene id: 7918:dnmt1
uniprot id: W5MKW5
uniprot id: W5MKX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

7918:pfdn6
gene id: 7918:pfdn6
uniprot id: W5LWJ2
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

7918:acta2
gene id: 7918:acta2
uniprot id: W5MG06
names: Similarity
messages: Belongs to the actin family.

7918:pskh1
gene id: 7918:pskh1
uniprot id: W5MI47
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:crmp1
gene id: 7918:crmp1
uniprot id: W5MVC3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

7918:tmeff2
gene id: 7918:tmeff2
uniprot id: W5MCN0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102686884
gene id: 7918:LOC102686884
uniprot id: W5N598
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

7918:ebag9
gene id: 7918:ebag9
uniprot id: W5M565
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

7918:LOC107079131
gene id: 7918:LOC107079131
uniprot id: W5MIW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

7918:rpl10
gene id: 7918:rpl10
uniprot id: W5NEL8
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

7918:phospho2
gene id: 7918:phospho2
uniprot id: W5NMS4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

7918:gprc5b
gene id: 7918:gprc5b
uniprot id: W5M4V4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:lamtor3
gene id: 7918:lamtor3
uniprot id: W5N176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

7918:chst1
gene id: 7918:chst1
uniprot id: W5NLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

7918:casc4
gene id: 7918:casc4
uniprot id: W5N8J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

7918:LOC102697098
gene id: 7918:LOC102697098
uniprot id: W5NAI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

7918:psma1
gene id: 7918:psma1
uniprot id: W5M5T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

7918:rnf167
gene id: 7918:rnf167
uniprot id: W5N851
names: Subcellular Location Annotation
messages: Membrane

7918:fam57a
gene id: 7918:fam57a
uniprot id: W5MIS9
names: Subcellular Location Annotation
messages: Membrane

7918:tmem218
gene id: 7918:tmem218
uniprot id: W5MDD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

7918:LOC107077917
gene id: 7918:LOC107077917
uniprot id: W5NDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

7918:nsa2
gene id: 7918:nsa2
uniprot id: W5MDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

7918:clu
gene id: 7918:clu
uniprot id: W5NJB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol

7918:LOC102697259
gene id: 7918:LOC102697259
uniprot id: W5MI91
names: Similarity
messages: Belongs to the perilipin family.

7918:lamb1
gene id: 7918:lamb1
uniprot id: W5NG27
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

7918:pla2g10
gene id: 7918:pla2g10
uniprot id: W5LX63
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

7918:fgfr2
gene id: 7918:fgfr2
uniprot id: W5MQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:zdhhc2
gene id: 7918:zdhhc2
uniprot id: W5N980
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

7918:tcp11
gene id: 7918:tcp11
uniprot id: W5MV71
names: Similarity
messages: Belongs to the TCP11 family.

7918:il12rb2
gene id: 7918:il12rb2
uniprot id: W5MJM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

7918:nf2
gene id: 7918:nf2
uniprot id: W5M7H1
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

7918:LOC102690701
gene id: 7918:LOC102690701
uniprot id: W5MU65
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:lypla2
gene id: 7918:lypla2
uniprot id: W5LYH2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

7918:cd247
gene id: 7918:cd247
uniprot id: W5MU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

7918:tyw3
gene id: 7918:tyw3
uniprot id: W5M6R5
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

7918:gpr3
gene id: 7918:gpr3
uniprot id: W5NP25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:LOC102686760
gene id: 7918:LOC102686760
uniprot id: W5NK07
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

7918:mycl
gene id: 7918:mycl
uniprot id: W5M1Y9
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

7918:s1pr3
gene id: 7918:s1pr3
uniprot id: W5NLZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:mtfr1
gene id: 7918:mtfr1
uniprot id: W5MBS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

7918:donson
gene id: 7918:donson
uniprot id: W5MYP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

7918:cplx2
gene id: 7918:cplx2
uniprot id: W5N0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

7918:rpl22
gene id: 7918:rpl22
uniprot id: W5MC08
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

7918:csnk1d
gene id: 7918:csnk1d
uniprot id: W5N3C6
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:lamtor1
gene id: 7918:lamtor1
uniprot id: W5MMA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

7918:lrrc8a
gene id: 7918:lrrc8a
uniprot id: W5MA41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

7918:LOC102690949
gene id: 7918:LOC102690949
uniprot id: W5MPS7
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:insig1
gene id: 7918:insig1
uniprot id: W5N440
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

7918:cript
gene id: 7918:cript
uniprot id: W5NHP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

7918:phox2b
gene id: 7918:phox2b
uniprot id: W5N5J7
names: Subcellular Location Annotation
messages: Nucleus

7918:zfpm2
gene id: 7918:zfpm2
uniprot id: W5MSZ3
names: Subcellular Location Annotation
messages: Nucleus

7918:nras
gene id: 7918:nras
uniprot id: W5MWN4
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:itpr1
gene id: 7918:itpr1
uniprot id: W5MYT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

7918:ntn4
gene id: 7918:ntn4
uniprot id: W5NFH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ifih1
gene id: 7918:ifih1
uniprot id: W5MPI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

7918:cnpy1
gene id: 7918:cnpy1
uniprot id: W5N426
names: Similarity
messages: Belongs to the canopy family.

7918:gsx1
gene id: 7918:gsx1
uniprot id: W5M9M8
names: Subcellular Location Annotation
messages: Nucleus

7918:gpc5
gene id: 7918:gpc5
uniprot id: W5MBH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

7918:acvr1c
gene id: 7918:acvr1c
uniprot id: W5MFA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

7918:slc4a2
gene id: 7918:slc4a2
uniprot id: W5MW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

7918:LOC102684477
gene id: 7918:LOC102684477
uniprot id: W5MUQ4
names: Subcellular Location Annotation
messages: Cytoplasm

7918:kif14
gene id: 7918:kif14
uniprot id: W5MLS0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:sgsm1
gene id: 7918:sgsm1
uniprot id: W5M930
names: Similarity
messages: Belongs to the RUTBC family.

7918:gatad1
gene id: 7918:gatad1
uniprot id: W5MXE3
names: Subcellular Location Annotation
messages: Nucleus

7918:smad1
gene id: 7918:smad1
uniprot id: W5MQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

7918:slc25a46
gene id: 7918:slc25a46
uniprot id: W5MWI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

7918:piwil2
gene id: 7918:piwil2
uniprot id: W5NEA8
names: Similarity
messages: Belongs to the argonaute family.

7918:hdac2
gene id: 7918:hdac2
uniprot id: W5NK25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

7918:rnd3
gene id: 7918:rnd3
uniprot id: W5M090
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

7918:dpy19l3
gene id: 7918:dpy19l3
uniprot id: W5MF53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

7918:LOC102686398
gene id: 7918:LOC102686398
uniprot id: W5MUI8
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

7918:LOC102691137
gene id: 7918:LOC102691137
uniprot id: W5M445
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

7918:slc27a6
gene id: 7918:slc27a6
uniprot id: W5MP42
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

7918:foxl2
gene id: 7918:foxl2
uniprot id: W5NLI5
names: Subcellular Location Annotation
messages: Nucleus

7918:anxa1
gene id: 7918:anxa1
uniprot id: W5MTW7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium

7918:scamp5
gene id: 7918:scamp5
uniprot id: W5NAA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

7918:rbm46
gene id: 7918:rbm46
uniprot id: W5MNW9
names: Subcellular Location Annotation
messages: Cytoplasm

7918:rybp
gene id: 7918:rybp
uniprot id: W5MUZ5
names: Subcellular Location Annotation
messages: Nucleus

7918:slc25a36
gene id: 7918:slc25a36
uniprot id: W5M9K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:tmc3
gene id: 7918:tmc3
uniprot id: W5N5B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

7918:LOC102698091
gene id: 7918:LOC102698091
uniprot id: W5NNQ9
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

7918:ern1
gene id: 7918:ern1
uniprot id: W5N8F3
names: Subcellular Location Annotation
messages: Membrane

7918:eif3l
gene id: 7918:eif3l
uniprot id: W5NH56
uniprot id: W5NH58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

7918:LOC102691665
gene id: 7918:LOC102691665
uniprot id: W5NM12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

7918:gpc6
gene id: 7918:gpc6
uniprot id: W5MBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

7918:LOC102687045
gene id: 7918:LOC102687045
uniprot id: W5N247
names: Similarity
messages: Belongs to the MS4A family.

7918:slc25a30
gene id: 7918:slc25a30
uniprot id: W5MDX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:LOC102694171
gene id: 7918:LOC102694171
uniprot id: W5N6I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

7918:mrps7
gene id: 7918:mrps7
uniprot id: W5N715
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

7918:LOC102698802
gene id: 7918:LOC102698802
uniprot id: W5NFX0
names: Similarity
messages: Belongs to the uridine kinase family.

7918:ovol3
gene id: 7918:ovol3
uniprot id: W5NC90
names: Subcellular Location Annotation
messages: Nucleus

7918:rpap2
gene id: 7918:rpap2
uniprot id: W5MBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.

7918:rab3gap1
gene id: 7918:rab3gap1
uniprot id: W5M0S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm
messages: Endoplasmic reticulum

7918:siah1
gene id: 7918:siah1
uniprot id: W5ML82
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

7918:nsf
gene id: 7918:nsf
uniprot id: W5N5U0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

7918:gpd1l
gene id: 7918:gpd1l
uniprot id: W5M2H7
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

7918:aldh6a1
gene id: 7918:aldh6a1
uniprot id: W5MYG1
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.

7918:mtfp1
gene id: 7918:mtfp1
uniprot id: W5ML65
names: Similarity
messages: Belongs to the MTFP1 family.

7918:apln
gene id: 7918:apln
uniprot id: W5NDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apelin family.
messages: extracellular space

7918:clg11h8orf37
gene id: 7918:clg11h8orf37
uniprot id: W5MNX0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

7918:loxl1
gene id: 7918:loxl1
uniprot id: W5NAA5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

7918:krtcap2
gene id: 7918:krtcap2
uniprot id: W5MIN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

7918:elmo2
gene id: 7918:elmo2
uniprot id: W5M492
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

7918:elp3
gene id: 7918:elp3
uniprot id: W5NGA8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

7918:LOC102691446
gene id: 7918:LOC102691446
uniprot id: W5MA50
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

7918:sptssa
gene id: 7918:sptssa
uniprot id: W5MT86
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:lpar1
gene id: 7918:lpar1
uniprot id: W5M430
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

7918:timm8a
gene id: 7918:timm8a
uniprot id: W5NDZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

7918:ogn
gene id: 7918:ogn
uniprot id: W5N8Y4
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

7918:senp7
gene id: 7918:senp7
uniprot id: W5MTA3
names: Similarity
messages: Belongs to the peptidase C48 family.

7918:obfc1
gene id: 7918:obfc1
uniprot id: W5N237
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

7918:LOC102691398
gene id: 7918:LOC102691398
uniprot id: W5MXC6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:dync1li1
gene id: 7918:dync1li1
uniprot id: W5LZU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

7918:ago2
gene id: 7918:ago2
uniprot id: W5MM32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

7918:c8a
gene id: 7918:c8a
uniprot id: W5MQR4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:grina
gene id: 7918:grina
uniprot id: W5MPX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

7918:cdk11a
gene id: 7918:cdk11a
uniprot id: W5MGP4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

7918:qsox1
gene id: 7918:qsox1
uniprot id: W5MSC8
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

7918:cldn2
gene id: 7918:cldn2
uniprot id: W5NLT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

7918:LOC107077156
gene id: 7918:LOC107077156
uniprot id: W5N4Q6
names: Similarity
messages: Belongs to the CFAP97 family.

7918:ndufb10
gene id: 7918:ndufb10
uniprot id: W5MR23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

7918:hoxa3
gene id: 7918:hoxa3
uniprot id: W5N1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

7918:csf1r
gene id: 7918:csf1r
uniprot id: W5MZ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:phax
gene id: 7918:phax
uniprot id: W5MPU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

7918:gch1
gene id: 7918:gch1
uniprot id: W5N2M9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

7918:gpcpd1
gene id: 7918:gpcpd1
uniprot id: W5NI69
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

7918:LOC102695966
gene id: 7918:LOC102695966
uniprot id: W5NAV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

7918:rpl37
gene id: 7918:rpl37
uniprot id: W5MZH3
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

7918:cdk5r2
gene id: 7918:cdk5r2
uniprot id: W5NMS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

7918:srp72
gene id: 7918:srp72
uniprot id: W5M3Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

7918:opn3
gene id: 7918:opn3
uniprot id: W5NIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

7918:nat9
gene id: 7918:nat9
uniprot id: W5MZA3
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

7918:zbed4
gene id: 7918:zbed4
uniprot id: W5NN02
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC107077761
gene id: 7918:LOC107077761
uniprot id: W5MZW9
names: Similarity
messages: Belongs to the HEBP family.

7918:cdk5
gene id: 7918:cdk5
uniprot id: W5MSH3
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:hrsp12
gene id: 7918:hrsp12
uniprot id: W5MUF4
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

7918:ttc4
gene id: 7918:ttc4
uniprot id: W5MQ81
names: Similarity
messages: Belongs to the TTC4 family.

7918:gngt2
gene id: 7918:gngt2
uniprot id: W5N619
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

7918:tbccd1
gene id: 7918:tbccd1
uniprot id: W5M920
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

7918:ispd
gene id: 7918:ispd
uniprot id: W5MZQ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

7918:dock1
gene id: 7918:dock1
uniprot id: W5MM11
names: Similarity
messages: Belongs to the DOCK family.

7918:dctn6
gene id: 7918:dctn6
uniprot id: W5N6K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.
messages: cytoskeleton

7918:aqp8
gene id: 7918:aqp8
uniprot id: W5MDP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

7918:LOC102687711
gene id: 7918:LOC102687711
uniprot id: W5MVY3
names: Similarity
messages: Belongs to the CD99 family.

7918:LOC102692732
gene id: 7918:LOC102692732
uniprot id: W5NCY9
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

7918:nipsnap1
gene id: 7918:nipsnap1
uniprot id: W5M6X8
names: Similarity
messages: Belongs to the NipSnap family.

7918:clstn2
gene id: 7918:clstn2
uniprot id: W5M9T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

7918:fam135a
gene id: 7918:fam135a
uniprot id: W5NKG8
names: Similarity
messages: Belongs to the FAM135 family.

7918:nipal4
gene id: 7918:nipal4
uniprot id: W5MUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

7918:LOC102693418
gene id: 7918:LOC102693418
uniprot id: W5LWZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

7918:gcnt3
gene id: 7918:gcnt3
uniprot id: W5NN52
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

7918:atp6ap2
gene id: 7918:atp6ap2
uniprot id: W5MMV7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

7918:panx2
gene id: 7918:panx2
uniprot id: W5NEM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

7918:tmc6
gene id: 7918:tmc6
uniprot id: W5N4K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

7918:myoc
gene id: 7918:myoc
uniprot id: W5MWJ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ythdf2
gene id: 7918:ythdf2
uniprot id: W5MDK4
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

7918:hoxb7
gene id: 7918:hoxb7
uniprot id: W5N7H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

7918:LOC102685351
gene id: 7918:LOC102685351
uniprot id: W5NJD5
names: Subcellular Location Annotation
messages: Nucleus

7918:lsm6
gene id: 7918:lsm6
uniprot id: W5MQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

7918:grik2
gene id: 7918:grik2
uniprot id: W5NIH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

7918:fes
gene id: 7918:fes
uniprot id: W5ND67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

7918:LOC102686226
gene id: 7918:LOC102686226
uniprot id: W5MS51
names: Similarity
messages: Belongs to the peptidase A1 family.

7918:slc9a3r1
gene id: 7918:slc9a3r1
uniprot id: W5MZ63
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

7918:prdx2
gene id: 7918:prdx2
uniprot id: W5MMI9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

7918:itgae
gene id: 7918:itgae
uniprot id: W5M6Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

7918:LOC102687958
gene id: 7918:LOC102687958
uniprot id: W5N5F2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion

7918:crtac1
gene id: 7918:crtac1
uniprot id: W5MR59
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ccnb3
gene id: 7918:ccnb3
uniprot id: W5NAH3
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

7918:dpf3
gene id: 7918:dpf3
uniprot id: W5N3J9
names: Similarity
messages: Belongs to the requiem/DPF family.

7918:cdk5rap1
gene id: 7918:cdk5rap1
uniprot id: W5M033
names: Similarity
messages: Belongs to the methylthiotransferase family. MiaB subfamily.

7918:frat2
gene id: 7918:frat2
uniprot id: W5NP72
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

7918:stom
gene id: 7918:stom
uniprot id: W5ME84
uniprot id: W5MEA2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

7918:foxp1
gene id: 7918:foxp1
uniprot id: W5MV48
names: Subcellular Location Annotation
messages: Nucleus

7918:pola1
gene id: 7918:pola1
uniprot id: W5M1E0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

7918:piezo1
gene id: 7918:piezo1
uniprot id: W5MBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Membrane

7918:uevld
gene id: 7918:uevld
uniprot id: W5MBH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

7918:lipg
gene id: 7918:lipg
uniprot id: W5MZT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:LOC102685801
gene id: 7918:LOC102685801
uniprot id: W5MGU5
names: Similarity
messages: Belongs to the neutral ceramidase family.

7918:fbn1
gene id: 7918:fbn1
uniprot id: W5N6M2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:hint3
gene id: 7918:hint3
uniprot id: W5NIE8
names: Similarity
messages: Belongs to the HINT family.

7918:psmb1
gene id: 7918:psmb1
uniprot id: W5NEK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

7918:gad1
gene id: 7918:gad1
uniprot id: W5MMB2
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

7918:prdm1
gene id: 7918:prdm1
uniprot id: W5NIF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

7918:ca2
gene id: 7918:ca2
uniprot id: W5N555
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

7918:wfikkn1
gene id: 7918:wfikkn1
uniprot id: W5MIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WFIKKN family.
messages: Secreted

7918:kif16b
gene id: 7918:kif16b
uniprot id: W5NGC9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:slc25a3
gene id: 7918:slc25a3
uniprot id: W5NEF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

7918:ube2g1
gene id: 7918:ube2g1
uniprot id: W5M3S2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:LOC102696020
gene id: 7918:LOC102696020
uniprot id: W5MPT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:pten
gene id: 7918:pten
uniprot id: W5MGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

7918:LOC102691943
gene id: 7918:LOC102691943
uniprot id: W5MQ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

7918:hapln3
gene id: 7918:hapln3
uniprot id: W5NA55
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:prox1
gene id: 7918:prox1
uniprot id: W5NJ21
names: Subcellular Location Annotation
messages: Nucleus

7918:zfhx3
gene id: 7918:zfhx3
uniprot id: W5M9H1
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102687255
gene id: 7918:LOC102687255
uniprot id: W5NMB8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

7918:LOC102696005
gene id: 7918:LOC102696005
uniprot id: W5MT19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

7918:LOC107077579
gene id: 7918:LOC107077579
uniprot id: W5MIE7
names: Similarity
messages: Belongs to the AKAP95 family.

7918:aldh4a1
gene id: 7918:aldh4a1
uniprot id: W5MB62
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

7918:lpcat1
gene id: 7918:lpcat1
uniprot id: W5MR02
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

7918:LOC102698526
gene id: 7918:LOC102698526
uniprot id: W5MBD6
names: Similarity
messages: Belongs to the nicastrin family.

7918:zbtb8os
gene id: 7918:zbtb8os
uniprot id: W5M2J6
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

7918:metap2
gene id: 7918:metap2
uniprot id: W5NFI0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

7918:snrpf
gene id: 7918:snrpf
uniprot id: W5NFH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

7918:ccdc149
gene id: 7918:ccdc149
uniprot id: W5N3G7
names: Similarity
messages: Belongs to the CCDC149 family.

7918:ubac2
gene id: 7918:ubac2
uniprot id: W5M5X2
names: Subcellular Location Annotation
messages: Membrane

7918:grm8
gene id: 7918:grm8
uniprot id: W5NFV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

7918:smad9
gene id: 7918:smad9
uniprot id: W5MPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

7918:mrpl34
gene id: 7918:mrpl34
uniprot id: W5M574
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

7918:galr1
gene id: 7918:galr1
uniprot id: W5M8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

7918:ankrd34b
gene id: 7918:ankrd34b
uniprot id: W5NLW9
names: Similarity
messages: Belongs to the ANKRD34 family.

7918:pias2
gene id: 7918:pias2
uniprot id: W5MI21
names: Similarity
messages: Belongs to the PIAS family.

7918:LOC107080041
gene id: 7918:LOC107080041
uniprot id: W5MEB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

7918:gnpat
gene id: 7918:gnpat
uniprot id: W5NFL2
names: Similarity
messages: Belongs to the GPAT/DAPAT family.

7918:cdh15
gene id: 7918:cdh15
uniprot id: W5MAX2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

7918:zgpat
gene id: 7918:zgpat
uniprot id: W5M0K9
names: Subcellular Location Annotation
messages: Nucleus

7918:gorasp2
gene id: 7918:gorasp2
uniprot id: W5MM78
names: Similarity
messages: Belongs to the GORASP family.

7918:anapc4
gene id: 7918:anapc4
uniprot id: W5N9M5
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

7918:fgd6
gene id: 7918:fgd6
uniprot id: W5NFI7
names: Subcellular Location Annotation
messages: cytoskeleton

7918:ccdc67
gene id: 7918:ccdc67
uniprot id: W5MKJ8
names: Similarity
messages: Belongs to the CEP63 family.

7918:arhgef9
gene id: 7918:arhgef9
uniprot id: W5NBG5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

7918:LOC102689651
gene id: 7918:LOC102689651
uniprot id: W5NMY1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:slc35a1
gene id: 7918:slc35a1
uniprot id: W5NJW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:hspb8
gene id: 7918:hspb8
uniprot id: W5M5Y3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

7918:LOC102692470
gene id: 7918:LOC102692470
uniprot id: W5MMT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

7918:gucy1a3
gene id: 7918:gucy1a3
uniprot id: W5MNU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

7918:chsy3
gene id: 7918:chsy3
uniprot id: W5MNV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

7918:LOC102687689
gene id: 7918:LOC102687689
uniprot id: W5MS82
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102686079
gene id: 7918:LOC102686079
uniprot id: W5NNJ5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:nrg1
gene id: 7918:nrg1
uniprot id: W5MY11
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

7918:LOC102699233
gene id: 7918:LOC102699233
uniprot id: W5NMI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

7918:gimd1
gene id: 7918:gimd1
uniprot id: W5N4N8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

7918:atxn10
gene id: 7918:atxn10
uniprot id: W5NK81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
messages: perinuclear region

7918:nsmce2
gene id: 7918:nsmce2
uniprot id: W5MV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

7918:usp16
gene id: 7918:usp16
uniprot id: W5MRJ8
names: Similarity
messages: Belongs to the peptidase C19 family.

7918:sppl3
gene id: 7918:sppl3
uniprot id: W5M4Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

7918:dnttip2
gene id: 7918:dnttip2
uniprot id: W5MTS6
names: Subcellular Location Annotation
messages: nucleolus

7918:LOC102698690
gene id: 7918:LOC102698690
uniprot id: W5NBT4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:fli1
gene id: 7918:fli1
uniprot id: W5M3T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:btbd10
gene id: 7918:btbd10
uniprot id: W5M8M0
uniprot id: W5M8P4
names: Subcellular Location Annotation
messages: Cytoplasm

7918:asrgl1
gene id: 7918:asrgl1
uniprot id: W5NH49
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

7918:scamp1
gene id: 7918:scamp1
uniprot id: W5MF54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

7918:sntg2
gene id: 7918:sntg2
uniprot id: W5NI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

7918:ppp2cb
gene id: 7918:ppp2cb
uniprot id: W5MXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

7918:hbp1
gene id: 7918:hbp1
uniprot id: W5NFS1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

7918:opn5
gene id: 7918:opn5
uniprot id: W5NID2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

7918:dusp4
gene id: 7918:dusp4
uniprot id: W5N301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

7918:LOC102697534
gene id: 7918:LOC102697534
uniprot id: W5N9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

7918:cebpb
gene id: 7918:cebpb
uniprot id: W5NPA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

7918:ppib
gene id: 7918:ppib
uniprot id: W5NCW0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

7918:med20
gene id: 7918:med20
uniprot id: W5N4L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

7918:npl
gene id: 7918:npl
uniprot id: W5MVZ7
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

7918:hmox2
gene id: 7918:hmox2
uniprot id: W5M3C3
names: Similarity
messages: Belongs to the heme oxygenase family.

7918:scd5
gene id: 7918:scd5
uniprot id: W5MXL1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

7918:ubiad1
gene id: 7918:ubiad1
uniprot id: W5MGX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

7918:pebp1
gene id: 7918:pebp1
uniprot id: W5M6B4
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

7918:LOC107075521
gene id: 7918:LOC107075521
uniprot id: W5MKT4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:gpr180
gene id: 7918:gpr180
uniprot id: W5MBX1
names: Subcellular Location Annotation
messages: Membrane

7918:chmp1a
gene id: 7918:chmp1a
uniprot id: W5M586
names: Similarity
messages: Belongs to the SNF7 family.

7918:haus3
gene id: 7918:haus3
uniprot id: W5M2Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

7918:wdr24
gene id: 7918:wdr24
uniprot id: W5M701
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR24 family.
messages: Lysosome membrane

7918:kif21a
gene id: 7918:kif21a
uniprot id: W5NGR6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:LOC102689385
gene id: 7918:LOC102689385
uniprot id: W5MSM1
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102684742
gene id: 7918:LOC102684742
uniprot id: W5NP71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit and a regulatory subunit.
messages: Membrane

7918:atrx
gene id: 7918:atrx
uniprot id: W5N8A1
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

7918:gap43
gene id: 7918:gap43
uniprot id: W5M469
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Cell membrane
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: filopodium membrane
messages: growth cone membrane

7918:rpgrip1l
gene id: 7918:rpgrip1l
uniprot id: W5MJV6
names: Similarity
messages: Belongs to the RPGRIP1 family.

7918:LOC102691733
gene id: 7918:LOC102691733
uniprot id: W5MZQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

7918:cnot1
gene id: 7918:cnot1
uniprot id: W5MGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

7918:clg2h9orf3
gene id: 7918:clg2h9orf3
uniprot id: W5MSJ1
names: Similarity
messages: Belongs to the peptidase M1 family.

7918:LOC102692145
gene id: 7918:LOC102692145
uniprot id: W5MQ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

7918:slc39a10
gene id: 7918:slc39a10
uniprot id: W5MCL2
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102696589
gene id: 7918:LOC102696589
uniprot id: W5NNK1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

7918:LOC102686991
gene id: 7918:LOC102686991
uniprot id: W5ME49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

7918:LOC107077915
gene id: 7918:LOC107077915
uniprot id: W5NE68
names: Similarity
messages: Belongs to the tumor necrosis factor family.

7918:arpin
gene id: 7918:arpin
uniprot id: W5NAY9
names: Similarity
messages: Belongs to the Arpin family.

7918:taf2
gene id: 7918:taf2
uniprot id: W5MS13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

7918:slc17a8
gene id: 7918:slc17a8
uniprot id: W5NDK8
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102686920
gene id: 7918:LOC102686920
uniprot id: W5NBF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

7918:kit
gene id: 7918:kit
uniprot id: W5N9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:melk
gene id: 7918:melk
uniprot id: W5N566
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

7918:map3k5
gene id: 7918:map3k5
uniprot id: W5NK77
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

7918:LOC107078243
gene id: 7918:LOC107078243
uniprot id: J3AMA0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:phka1
gene id: 7918:phka1
uniprot id: W5NAZ3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

7918:grm4
gene id: 7918:grm4
uniprot id: W5MUR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

7918:LOC102688307
gene id: 7918:LOC102688307
uniprot id: W5NLS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:dgkq
gene id: 7918:dgkq
uniprot id: W5N2P4
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

7918:psmc2
gene id: 7918:psmc2
uniprot id: W5NGB7
names: Similarity
messages: Belongs to the AAA ATPase family.

7918:dgat2
gene id: 7918:dgat2
uniprot id: W5MBB3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:cav1
gene id: 7918:cav1
uniprot id: W5NEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

7918:chst11
gene id: 7918:chst11
uniprot id: W5ND03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:rpl23
gene id: 7918:rpl23
uniprot id: W5N8E8
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

7918:rpa3
gene id: 7918:rpa3
uniprot id: W5MZ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

7918:slc6a3
gene id: 7918:slc6a3
uniprot id: W5MR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

7918:pold3
gene id: 7918:pold3
uniprot id: W5M2S8
names: Subcellular Location Annotation
messages: Nucleus

7918:pth1r
gene id: 7918:pth1r
uniprot id: W5MT69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

7918:tmem41a
gene id: 7918:tmem41a
uniprot id: W5MTJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

7918:sesn3
gene id: 7918:sesn3
uniprot id: W5MLE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

7918:tmem233
gene id: 7918:tmem233
uniprot id: W5M030
names: Similarity
messages: Belongs to the CD225/Dispanin family.

7918:fam96b
gene id: 7918:fam96b
uniprot id: W5MC32
names: Similarity
messages: Belongs to the MIP18 family.

7918:upk1b
gene id: 7918:upk1b
uniprot id: W5M4D6
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102686084
gene id: 7918:LOC102686084
uniprot id: W5NF60
names: Similarity
messages: Belongs to the peptidase C2 family.

7918:amacr
gene id: 7918:amacr
uniprot id: W5N3E7
names: Similarity
messages: Belongs to the CoA-transferase III family.

7918:glyr1
gene id: 7918:glyr1
uniprot id: W5LYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

7918:lhfp
gene id: 7918:lhfp
uniprot id: W5MQU1
names: Subcellular Location Annotation
messages: Membrane

7918:cwf19l2
gene id: 7918:cwf19l2
uniprot id: W5MIU9
names: Similarity
messages: Belongs to the CWF19 family.

7918:fbn2
gene id: 7918:fbn2
uniprot id: W5MP95
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:dhx15
gene id: 7918:dhx15
uniprot id: W5N3I5
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

7918:LOC102690649
gene id: 7918:LOC102690649
uniprot id: W5NE92
names: Similarity
messages: Belongs to the AAA ATPase family.

7918:sox11
gene id: 7918:sox11
uniprot id: W5NNA0
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102697166
gene id: 7918:LOC102697166
uniprot id: W5MTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

7918:kif4a
gene id: 7918:kif4a
uniprot id: W5N8U7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:bloc1s2
gene id: 7918:bloc1s2
uniprot id: W5MQM2
names: Similarity
messages: Belongs to the BLOC1S2 family.

7918:gabra5
gene id: 7918:gabra5
uniprot id: W5MP10
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:emc6
gene id: 7918:emc6
uniprot id: W5NLM1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:nr5a2
gene id: 7918:nr5a2
uniprot id: W5MLP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

7918:ino80c
gene id: 7918:ino80c
uniprot id: W5MD85
names: Subcellular Location Annotation
messages: Nucleus

7918:lhx2
gene id: 7918:lhx2
uniprot id: W5MD70
names: Subcellular Location Annotation
messages: Nucleus

7918:egr3
gene id: 7918:egr3
uniprot id: W5NCM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

7918:epgn
gene id: 7918:epgn
uniprot id: W5N2G6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102691232
gene id: 7918:LOC102691232
uniprot id: W5M3Z9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:LOC107079304
gene id: 7918:LOC107079304
uniprot id: W5N6Y2
names: Similarity
messages: Belongs to the tachykinin family.

7918:mfsd6
gene id: 7918:mfsd6
uniprot id: W5MUR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

7918:aff4
gene id: 7918:aff4
uniprot id: W5MX90
names: Similarity
messages: Belongs to the AF4 family.

7918:tmem201
gene id: 7918:tmem201
uniprot id: W5MJ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

7918:fam69c
gene id: 7918:fam69c
uniprot id: W5N2M5
names: Similarity
messages: Belongs to the DIPK family.

7918:tmem43
gene id: 7918:tmem43
uniprot id: W5N620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

7918:ak2
gene id: 7918:ak2
uniprot id: W5LYR1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.

7918:sema3f
gene id: 7918:sema3f
uniprot id: W5MYD6
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:cdc37
gene id: 7918:cdc37
uniprot id: W5ML97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

7918:nsun4
gene id: 7918:nsun4
uniprot id: W5M926
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

7918:trabd2b
gene id: 7918:trabd2b
uniprot id: W5MVQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

7918:LOC102692997
gene id: 7918:LOC102692997
uniprot id: W5MND6
names: Similarity
messages: Belongs to the GADD45 family.

7918:LOC102697183
gene id: 7918:LOC102697183
uniprot id: W5MLD9
names: Subcellular Location Annotation
messages: Membrane

7918:drgx
gene id: 7918:drgx
uniprot id: W5M989
names: Subcellular Location Annotation
messages: Nucleus

7918:med15
gene id: 7918:med15
uniprot id: W5MHF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

7918:slc13a3
gene id: 7918:slc13a3
uniprot id: W5M237
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

7918:sema4f
gene id: 7918:sema4f
uniprot id: W5LZY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102698103
gene id: 7918:LOC102698103
uniprot id: W5NFY3
uniprot id: W5NFY5
names: Similarity
messages: Belongs to the PACS family.

7918:mterf4
gene id: 7918:mterf4
uniprot id: W5MFX0
names: Similarity
messages: Belongs to the mTERF family.

7918:whamm
gene id: 7918:whamm
uniprot id: W5N5P9
names: Subcellular Location Annotation
messages: Membrane

7918:nmd3
gene id: 7918:nmd3
uniprot id: W5M763
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

7918:osbp2
gene id: 7918:osbp2
uniprot id: W5MN37
names: Similarity
messages: Belongs to the OSBP family.

7918:hmx2
gene id: 7918:hmx2
uniprot id: W5MNI3
names: Subcellular Location Annotation
messages: Nucleus

7918:igfbp3
gene id: 7918:igfbp3
uniprot id: W5N652
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:LOC107078452
gene id: 7918:LOC107078452
uniprot id: W5NKH4
names: Similarity
messages: Belongs to the peptidase S8 family.

7918:acad8
gene id: 7918:acad8
uniprot id: W5MCH4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

7918:lmod1
gene id: 7918:lmod1
uniprot id: W5MVD2
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

7918:sf3b6
gene id: 7918:sf3b6
uniprot id: W5NIA0
names: Subcellular Location Annotation
messages: Nucleus

7918:clg3h11orf70
gene id: 7918:clg3h11orf70
uniprot id: W5MEL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

7918:yeats2
gene id: 7918:yeats2
uniprot id: W5MG18
names: Subcellular Location Annotation
messages: Nucleus

7918:narfl
gene id: 7918:narfl
uniprot id: W5MCX7
names: Similarity
messages: Belongs to the NARF family.

7918:slc30a5
gene id: 7918:slc30a5
uniprot id: W5MWW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: trans-Golgi network membrane

7918:ptprn2
gene id: 7918:ptprn2
uniprot id: W5N3T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

7918:xkr8
gene id: 7918:xkr8
uniprot id: W5M9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

7918:tm4sf19
gene id: 7918:tm4sf19
uniprot id: W5MU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

7918:LOC102692089
gene id: 7918:LOC102692089
uniprot id: W5LXV0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:srsf1
gene id: 7918:srsf1
uniprot id: W5MFT3
names: Similarity
messages: Belongs to the splicing factor SR family.

7918:foxb1
gene id: 7918:foxb1
uniprot id: W5NN51
names: Subcellular Location Annotation
messages: Nucleus

7918:gapdh
gene id: 7918:gapdh
uniprot id: W5MJ53
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

7918:gata2
gene id: 7918:gata2
uniprot id: W5NB88
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102683252
gene id: 7918:LOC102683252
uniprot id: W5NHY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.
messages: May affect the rate of fibrils formation.
messages: extracellular matrix

7918:cep19
gene id: 7918:cep19
uniprot id: W5MI02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

7918:LOC102684306
gene id: 7918:LOC102684306
uniprot id: W5NIK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

7918:fgf5
gene id: 7918:fgf5
uniprot id: W5MK13
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

7918:LOC107075583
gene id: 7918:LOC107075583
uniprot id: W5M9R3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:syt14
gene id: 7918:syt14
uniprot id: W5NKS5
names: Similarity
messages: Belongs to the synaptotagmin family.

7918:rspo2
gene id: 7918:rspo2
uniprot id: W5M5M8
names: Similarity
messages: Belongs to the R-spondin family.

7918:psmd1
gene id: 7918:psmd1
uniprot id: W5MB58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

7918:zdhhc22
gene id: 7918:zdhhc22
uniprot id: W5MYY5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

7918:kif2a
gene id: 7918:kif2a
uniprot id: W5MM89
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:mapk1
gene id: 7918:mapk1
uniprot id: W5M1V2
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

7918:foxm1
gene id: 7918:foxm1
uniprot id: W5NII9
names: Subcellular Location Annotation
messages: Nucleus

7918:slc35b2
gene id: 7918:slc35b2
uniprot id: W5NHZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

7918:LOC102683352
gene id: 7918:LOC102683352
uniprot id: W5MH98
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

7918:cdh5
gene id: 7918:cdh5
uniprot id: W5MD02
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

7918:LOC102697551
gene id: 7918:LOC102697551
uniprot id: W5MPZ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:fam168a
gene id: 7918:fam168a
uniprot id: W5MGP2
names: Similarity
messages: Belongs to the FAM168 family.

7918:p2ry13
gene id: 7918:p2ry13
uniprot id: W5NLH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:LOC102694784
gene id: 7918:LOC102694784
uniprot id: W5NBG6
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:kcnk6
gene id: 7918:kcnk6
uniprot id: W5NB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

7918:atad1
gene id: 7918:atad1
uniprot id: W5MGH4
names: Similarity
messages: Belongs to the AAA ATPase family.

7918:flna
gene id: 7918:flna
uniprot id: W5NEN1
names: Similarity
messages: Belongs to the filamin family.

7918:xrcc5
gene id: 7918:xrcc5
uniprot id: W5MU37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase.

7918:sv2c
gene id: 7918:sv2c
uniprot id: W5ME58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

7918:lpin2
gene id: 7918:lpin2
uniprot id: W5MZ40
names: Similarity
messages: Belongs to the lipin family.

7918:ppm1a
gene id: 7918:ppm1a
uniprot id: W5MVB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

7918:pdx1
gene id: 7918:pdx1
uniprot id: W5M9N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

7918:tnmd
gene id: 7918:tnmd
uniprot id: W5NE27
names: Similarity
messages: Belongs to the chondromodulin-1 family.

7918:snf8
gene id: 7918:snf8
uniprot id: W5N7M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

7918:xrcc1
gene id: 7918:xrcc1
uniprot id: W5MEK0
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102688593
gene id: 7918:LOC102688593
uniprot id: W5N5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

7918:shq1
gene id: 7918:shq1
uniprot id: W5MUY3
names: Similarity
messages: Belongs to the SHQ1 family.

7918:dennd6a
gene id: 7918:dennd6a
uniprot id: W5N6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

7918:mtg2
gene id: 7918:mtg2
uniprot id: W5M7Q4
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

7918:LOC102684175
gene id: 7918:LOC102684175
uniprot id: W5M652
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:gria2
gene id: 7918:gria2
uniprot id: W5MNG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

7918:unc5b
gene id: 7918:unc5b
uniprot id: W5MQV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

7918:dopey2
gene id: 7918:dopey2
uniprot id: W5MIM8
names: Similarity
messages: Belongs to the dopey family.

7918:rplp0
gene id: 7918:rplp0
uniprot id: W5M0N0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

7918:LOC107079953
gene id: 7918:LOC107079953
uniprot id: W5M200
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:snx18
gene id: 7918:snx18
uniprot id: W5MJB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

7918:clg10h1orf123
gene id: 7918:clg10h1orf123
uniprot id: W5MG92
names: Similarity
messages: Belongs to the UPF0587 family.

7918:tssk6
gene id: 7918:tssk6
uniprot id: W5NM79
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:lypla1
gene id: 7918:lypla1
uniprot id: W5MEQ7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

7918:mphosph10
gene id: 7918:mphosph10
uniprot id: W5N8B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

7918:lhfpl3
gene id: 7918:lhfpl3
uniprot id: W5NEJ4
names: Subcellular Location Annotation
messages: Membrane

7918:top1mt
gene id: 7918:top1mt
uniprot id: W5MPB0
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

7918:cpeb4
gene id: 7918:cpeb4
uniprot id: W5MRX5
names: Similarity
messages: Belongs to the RRM CPEB family.

7918:LOC102689202
gene id: 7918:LOC102689202
uniprot id: W5NMJ3
names: Subcellular Location Annotation
messages: Nucleus

7918:hoxb8
gene id: 7918:hoxb8
uniprot id: W5N7H2
names: Subcellular Location Annotation
messages: Nucleus

7918:dynll1
gene id: 7918:dynll1
uniprot id: W5MQD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

7918:LOC102695732
gene id: 7918:LOC102695732
uniprot id: W5NB47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:mpeg1
gene id: 7918:mpeg1
uniprot id: W5MMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

7918:cdh18
gene id: 7918:cdh18
uniprot id: W5N567
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

7918:LOC102687133
gene id: 7918:LOC102687133
uniprot id: W5N240
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

7918:pam16
gene id: 7918:pam16
uniprot id: W5M329
names: Similarity
messages: Belongs to the TIM16/PAM16 family.

7918:ndufa1
gene id: 7918:ndufa1
uniprot id: W5NDP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

7918:ppp1r3c
gene id: 7918:ppp1r3c
uniprot id: W5MFU8
names: Domain
names: Function
names: Subunit
messages: Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
messages: Interacts with PPP1CC catalytic subunit of PP1 and associates with glycogen. Forms complexes with glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.
messages: The N-terminal region is required for binding to PP1, the central region is required for binding to glycogen and the C-terminal region is required for binding to glycogen phosphorylase glycogen synthase and phosphorylase kinase.

7918:kpna5
gene id: 7918:kpna5
uniprot id: W5NKK4
names: Similarity
messages: Belongs to the importin alpha family.

7918:LOC102682856
gene id: 7918:LOC102682856
uniprot id: W5MDT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

7918:LOC102685718
gene id: 7918:LOC102685718
uniprot id: W5NB41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

7918:slc35f1
gene id: 7918:slc35f1
uniprot id: W5NL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

7918:LOC102696199
gene id: 7918:LOC102696199
uniprot id: W5MVN1
names: Subcellular Location Annotation
messages: cytoskeleton

7918:srd5a2
gene id: 7918:srd5a2
uniprot id: W5NG83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

7918:capn6
gene id: 7918:capn6
uniprot id: W5N8X1
names: Similarity
messages: Belongs to the peptidase C2 family.

7918:syt17
gene id: 7918:syt17
uniprot id: W5MJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Membrane

7918:clcn2
gene id: 7918:clcn2
uniprot id: W5MQT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

7918:slc2a4
gene id: 7918:slc2a4
uniprot id: W5N8U2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

7918:p3h1
gene id: 7918:p3h1
uniprot id: W5LY79
names: Similarity
messages: Belongs to the leprecan family.

7918:myb
gene id: 7918:myb
uniprot id: W5NH90
names: Subcellular Location Annotation
messages: Nucleus

7918:uxs1
gene id: 7918:uxs1
uniprot id: W5MQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

7918:KEF94 p07
gene id: 7918:KEF94_p07
uniprot id: Q8HQM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

7918:rrp1b
gene id: 7918:rrp1b
uniprot id: W5M922
names: Similarity
messages: Belongs to the RRP1 family.

7918:LOC102699074
gene id: 7918:LOC102699074
uniprot id: W5MZK0
names: Similarity
messages: Belongs to the copine family.

7918:LOC102692216
gene id: 7918:LOC102692216
uniprot id: W5MRU8
names: Cofactor
messages: Binds 1 Fe cation per subunit.

7918:LOC102690906
gene id: 7918:LOC102690906
uniprot id: W5MHQ7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

7918:nol11
gene id: 7918:nol11
uniprot id: W5N807
names: Subcellular Location Annotation
messages: nucleolus

7918:scarb1
gene id: 7918:scarb1
uniprot id: W5M0W2
names: Similarity
messages: Belongs to the CD36 family.

7918:dctn5
gene id: 7918:dctn5
uniprot id: W5MEI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

7918:sohlh2
gene id: 7918:sohlh2
uniprot id: W5MPC0
names: Subcellular Location Annotation
messages: Nucleus

7918:ide
gene id: 7918:ide
uniprot id: W5MJN7
names: Similarity
messages: Belongs to the peptidase M16 family.

7918:nkx6-2
gene id: 7918:nkx6-2
uniprot id: W5MKR6
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102687167
gene id: 7918:LOC102687167
uniprot id: W5NML2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:LOC102697499
gene id: 7918:LOC102697499
uniprot id: W5NII2
names: Similarity
messages: Belongs to the ARTD/PARP family.

7918:rpe
gene id: 7918:rpe
uniprot id: W5MBE7
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

7918:LOC102695383
gene id: 7918:LOC102695383
uniprot id: W5MYU5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

7918:kcnk5
gene id: 7918:kcnk5
uniprot id: W5NKS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

7918:nkain4
gene id: 7918:nkain4
uniprot id: W5MCH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

7918:LOC102686962
gene id: 7918:LOC102686962
uniprot id: W5MMH5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

7918:LOC102692101
gene id: 7918:LOC102692101
uniprot id: W5MMC1
names: Subcellular Location Annotation
messages: Membrane

7918:ca5a
gene id: 7918:ca5a
uniprot id: W5M7A4
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

7918:sema3a
gene id: 7918:sema3a
uniprot id: W5NHZ6
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102685659
gene id: 7918:LOC102685659
uniprot id: W5N2Y9
names: Subcellular Location Annotation
messages: Nucleus

7918:acss2
gene id: 7918:acss2
uniprot id: W5MEC9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

7918:phox2a
gene id: 7918:phox2a
uniprot id: W5MLX3
names: Subcellular Location Annotation
messages: Nucleus

7918:stoml1
gene id: 7918:stoml1
uniprot id: W5NCM4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

7918:kmt5b
gene id: 7918:kmt5b
uniprot id: W5M410
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

7918:exoc1
gene id: 7918:exoc1
uniprot id: W5N9I5
uniprot id: W5N9I8
names: Similarity
messages: Belongs to the SEC3 family.

7918:LOC102682481
gene id: 7918:LOC102682481
uniprot id: W5NG01
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:kcnj3
gene id: 7918:kcnj3
uniprot id: W5MEV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

7918:xpa
gene id: 7918:xpa
uniprot id: W5MTK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

7918:LOC102698209
gene id: 7918:LOC102698209
uniprot id: W5NP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:LOC102698392
gene id: 7918:LOC102698392
uniprot id: W5NIB5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

7918:LOC102684999
gene id: 7918:LOC102684999
uniprot id: W5NC56
names: Subcellular Location Annotation
messages: Nucleus

7918:tpd52l1
gene id: 7918:tpd52l1
uniprot id: W5NL47
uniprot id: W5NL49
names: Similarity
messages: Belongs to the TPD52 family.

7918:pik3ca
gene id: 7918:pik3ca
uniprot id: W5LYU4
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

7918:prcp
gene id: 7918:prcp
uniprot id: W5MF96
names: Similarity
messages: Belongs to the peptidase S28 family.

7918:tprg1l
gene id: 7918:tprg1l
uniprot id: W5MDF2
names: Similarity
messages: Belongs to the TPRG1 family.

7918:intu
gene id: 7918:intu
uniprot id: W5N4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

7918:elavl1
gene id: 7918:elavl1
uniprot id: W5LW06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

7918:cpe
gene id: 7918:cpe
uniprot id: W5MME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Membrane
messages: secretory vesicle membrane

7918:bmpr1a
gene id: 7918:bmpr1a
uniprot id: W5N3Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

7918:clic3
gene id: 7918:clic3
uniprot id: W5M1H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

7918:mtmr1
gene id: 7918:mtmr1
uniprot id: W5NB24
uniprot id: W5NB26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

7918:LOC102695765
gene id: 7918:LOC102695765
uniprot id: W5M9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

7918:slc2a11
gene id: 7918:slc2a11
uniprot id: W5MIB0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

7918:LOC102682726
gene id: 7918:LOC102682726
uniprot id: W5MYG7
names: Subcellular Location Annotation
messages: Nucleus

7918:nono
gene id: 7918:nono
uniprot id: W5NBY9
names: Subcellular Location Annotation
messages: Nucleus speckle

7918:LOC102683657
gene id: 7918:LOC102683657
uniprot id: W5MQV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

7918:hmbs
gene id: 7918:hmbs
uniprot id: W5M7T4
names: Similarity
messages: Belongs to the HMBS family.

7918:LOC107077152
gene id: 7918:LOC107077152
uniprot id: W5N7R5
names: Similarity
messages: Belongs to the SPARC family.

7918:tgm2
gene id: 7918:tgm2
uniprot id: W5LYX2
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

7918:LOC102682218
gene id: 7918:LOC102682218
uniprot id: W5MXQ6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:snx11
gene id: 7918:snx11
uniprot id: W5N7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

7918:LOC102684614
gene id: 7918:LOC102684614
uniprot id: W5LYB1
names: Subunit
messages: Monomer.

7918:shox2
gene id: 7918:shox2
uniprot id: W5M878
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102695813
gene id: 7918:LOC102695813
uniprot id: W5MHW2
names: Similarity
messages: Belongs to the MIF family.

7918:usp30
gene id: 7918:usp30
uniprot id: W5MAJ6
names: Similarity
messages: Belongs to the peptidase C19 family.

7918:sumo3
gene id: 7918:sumo3
uniprot id: W5MSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

7918:wisp3
gene id: 7918:wisp3
uniprot id: W5NK35
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:egfl7
gene id: 7918:egfl7
uniprot id: W5M7I2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:impad1
gene id: 7918:impad1
uniprot id: W5MDF4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

7918:dclk3
gene id: 7918:dclk3
uniprot id: W5MBJ0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

7918:mrpl16
gene id: 7918:mrpl16
uniprot id: W5MYK8
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

7918:dact2
gene id: 7918:dact2
uniprot id: W5NH68
names: Similarity
messages: Belongs to the dapper family.

7918:tpra1
gene id: 7918:tpra1
uniprot id: W5N8P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

7918:LOC102687816
gene id: 7918:LOC102687816
uniprot id: W5N5S2
names: Similarity
messages: Belongs to the ARTD/PARP family.

7918:hoxb1
gene id: 7918:hoxb1
uniprot id: W5N7F2
names: Subcellular Location Annotation
messages: Nucleus

7918:nmnat2
gene id: 7918:nmnat2
uniprot id: W5M1V1
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

7918:cdh7
gene id: 7918:cdh7
uniprot id: W5N2Z5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

7918:top1
gene id: 7918:top1
uniprot id: W5MAN7
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

7918:atp5g3
gene id: 7918:atp5g3
uniprot id: W5MK15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

7918:vegfa
gene id: 7918:vegfa
uniprot id: W5NGF6
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

7918:adgra1
gene id: 7918:adgra1
uniprot id: W5MKE3
names: Subcellular Location Annotation
messages: Membrane

7918:marveld2
gene id: 7918:marveld2
uniprot id: W5M9P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

7918:capn7
gene id: 7918:capn7
uniprot id: W5M127
names: Similarity
messages: Belongs to the peptidase C2 family.

7918:frem3
gene id: 7918:frem3
uniprot id: W5MRA3
names: Similarity
messages: Belongs to the FRAS1 family.

7918:paqr8
gene id: 7918:paqr8
uniprot id: W5NN85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

7918:ulk3
gene id: 7918:ulk3
uniprot id: W5NBH8
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:cope
gene id: 7918:cope
uniprot id: W5M8V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

7918:LOC102686735
gene id: 7918:LOC102686735
uniprot id: W5M1G8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

7918:pgm2l1
gene id: 7918:pgm2l1
uniprot id: W5M2Y0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

7918:lmln
gene id: 7918:lmln
uniprot id: W5M4S7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

7918:lancl3
gene id: 7918:lancl3
uniprot id: W5MM88
names: Similarity
messages: Belongs to the LanC-like protein family.

7918:ptgis
gene id: 7918:ptgis
uniprot id: W5M5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

7918:brox
gene id: 7918:brox
uniprot id: W5NI13
names: Similarity
messages: Belongs to the BROX family.

7918:LOC102683298
gene id: 7918:LOC102683298
uniprot id: W5NC03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

7918:vamp1
gene id: 7918:vamp1
uniprot id: W5MJN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

7918:lmnb1
gene id: 7918:lmnb1
uniprot id: W5MPR1
names: Similarity
messages: Belongs to the intermediate filament family.

7918:skp1
gene id: 7918:skp1
uniprot id: W5MVY0
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

7918:vbp1
gene id: 7918:vbp1
uniprot id: W5NCL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

7918:hspb7
gene id: 7918:hspb7
uniprot id: W5MMN1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

7918:paqr6
gene id: 7918:paqr6
uniprot id: W5MP43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

7918:tor3a
gene id: 7918:tor3a
uniprot id: W5MUA9
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

7918:LOC102693775
gene id: 7918:LOC102693775
uniprot id: W5NHP8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

7918:ehf
gene id: 7918:ehf
uniprot id: W5LZE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:rpl29
gene id: 7918:rpl29
uniprot id: W5N8Q2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

7918:gnrh1
gene id: 7918:gnrh1
uniprot id: W5NCT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins.

7918:aprt
gene id: 7918:aprt
uniprot id: W5MBF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm

7918:LOC102690813
gene id: 7918:LOC102690813
uniprot id: W5NH02
names: Similarity
messages: Belongs to the VHL family.

7918:LOC102684193
gene id: 7918:LOC102684193
uniprot id: W5LYF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

7918:csnk1g3
gene id: 7918:csnk1g3
uniprot id: W5MQ25
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

7918:LOC102694349
gene id: 7918:LOC102694349
uniprot id: W5MCC7
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion

7918:ube2d1
gene id: 7918:ube2d1
uniprot id: W5MHC2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:plod2
gene id: 7918:plod2
uniprot id: W5MM12
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

7918:timm50
gene id: 7918:timm50
uniprot id: W5NBT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Mitochondrion inner membrane

7918:adamts16
gene id: 7918:adamts16
uniprot id: W5MQS8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:LOC102696699
gene id: 7918:LOC102696699
uniprot id: W5N3B6
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:LOC102683363
gene id: 7918:LOC102683363
uniprot id: W5N0D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

7918:itgav
gene id: 7918:itgav
uniprot id: W5MIN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

7918:fignl1
gene id: 7918:fignl1
uniprot id: W5NP70
names: Similarity
messages: Belongs to the AAA ATPase family.

7918:eif3g
gene id: 7918:eif3g
uniprot id: W5MKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

7918:csrnp3
gene id: 7918:csrnp3
uniprot id: W5MNW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

7918:LOC102693976
gene id: 7918:LOC102693976
uniprot id: W5M977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

7918:tacr1
gene id: 7918:tacr1
uniprot id: W5NE53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:aatf
gene id: 7918:aatf
uniprot id: W5MC79
names: Similarity
messages: Belongs to the AATF family.

7918:mpv17l2
gene id: 7918:mpv17l2
uniprot id: W5M1I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

7918:nr2e3
gene id: 7918:nr2e3
uniprot id: W5NCS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:slc4a10
gene id: 7918:slc4a10
uniprot id: W5MPV9
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

7918:tp53
gene id: 7918:tp53
uniprot id: W5N8V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

7918:cul4a
gene id: 7918:cul4a
uniprot id: W5MUF3
names: Similarity
messages: Belongs to the cullin family.

7918:LOC107075332
gene id: 7918:LOC107075332
uniprot id: W5MQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

7918:ethe1
gene id: 7918:ethe1
uniprot id: W5MEU1
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

7918:mogs
gene id: 7918:mogs
uniprot id: W5M373
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

7918:LOC102693234
gene id: 7918:LOC102693234
uniprot id: W5MUP5
names: Similarity
messages: Belongs to the FRAS1 family.

7918:LOC102682872
gene id: 7918:LOC102682872
uniprot id: W5ME55
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:mb21d2
gene id: 7918:mb21d2
uniprot id: W5MSQ9
names: Similarity
messages: Belongs to the mab-21 family.

7918:prepl
gene id: 7918:prepl
uniprot id: W5NHW9
names: Similarity
messages: Belongs to the peptidase S9A family.

7918:camkmt
gene id: 7918:camkmt
uniprot id: W5NHV8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:bmpr1b
gene id: 7918:bmpr1b
uniprot id: W5N5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

7918:slc25a42
gene id: 7918:slc25a42
uniprot id: W5MBR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:slc25a4
gene id: 7918:slc25a4
uniprot id: W5N8M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

7918:stard3nl
gene id: 7918:stard3nl
uniprot id: W5N086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Membrane

7918:unc45a
gene id: 7918:unc45a
uniprot id: W5ND84
names: Subcellular Location Annotation
messages: perinuclear region

7918:zdhhc7
gene id: 7918:zdhhc7
uniprot id: W5LZC9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

7918:mmaa
gene id: 7918:mmaa
uniprot id: W5MQY5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

7918:LOC102684556
gene id: 7918:LOC102684556
uniprot id: W5MEV9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

7918:tomm20
gene id: 7918:tomm20
uniprot id: W5NG25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

7918:cecr1
gene id: 7918:cecr1
uniprot id: W5NIL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

7918:pop4
gene id: 7918:pop4
uniprot id: W5MEE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

7918:hadhb
gene id: 7918:hadhb
uniprot id: W5NHQ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

7918:emc2
gene id: 7918:emc2
uniprot id: W5M5I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

7918:prpf38b
gene id: 7918:prpf38b
uniprot id: W5MMD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

7918:sft2d3
gene id: 7918:sft2d3
uniprot id: W5NLK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

7918:LOC102697178
gene id: 7918:LOC102697178
uniprot id: W5MTC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

7918:LOC102684155
gene id: 7918:LOC102684155
uniprot id: W5NA02
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

7918:fam189a1
gene id: 7918:fam189a1
uniprot id: W5N8D5
names: Similarity
messages: Belongs to the ENTREP family.

7918:ptpn2
gene id: 7918:ptpn2
uniprot id: W5MTN1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

7918:lipi
gene id: 7918:lipi
uniprot id: W5MT16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

7918:wif1
gene id: 7918:wif1
uniprot id: W5NGZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC107077149
gene id: 7918:LOC107077149
uniprot id: W5NFT0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:flnc
gene id: 7918:flnc
uniprot id: W5NFM5
names: Similarity
messages: Belongs to the filamin family.

7918:htra4
gene id: 7918:htra4
uniprot id: W5ND81
names: Similarity
messages: Belongs to the peptidase S1C family.

7918:nr2f2
gene id: 7918:nr2f2
uniprot id: W5NAS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:slc18a3
gene id: 7918:slc18a3
uniprot id: W5NNX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

7918:stag1
gene id: 7918:stag1
uniprot id: W5MLD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

7918:abcc3
gene id: 7918:abcc3
uniprot id: W5MYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

7918:LOC102686515
gene id: 7918:LOC102686515
uniprot id: W5NAM2
names: Subcellular Location Annotation
messages: Membrane

7918:arl5b
gene id: 7918:arl5b
uniprot id: W5MY42
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

7918:tmem126a
gene id: 7918:tmem126a
uniprot id: W5MDK6
names: Subcellular Location Annotation
messages: Membrane

7918:nfe2l3
gene id: 7918:nfe2l3
uniprot id: W5N1C4
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

7918:cemip
gene id: 7918:cemip
uniprot id: W5N562
names: Similarity
messages: Belongs to the CEMIP family.

7918:LOC102682223
gene id: 7918:LOC102682223
uniprot id: W5N0A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

7918:mpp1
gene id: 7918:mpp1
uniprot id: W5N8I4
names: Similarity
messages: Belongs to the MAGUK family.

7918:LOC102695679
gene id: 7918:LOC102695679
uniprot id: W5MAY1
names: Similarity
messages: Belongs to the importin alpha family.

7918:sh3bp5
gene id: 7918:sh3bp5
uniprot id: W5M155
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

7918:mrpl3
gene id: 7918:mrpl3
uniprot id: W5M025
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

7918:opn4
gene id: 7918:opn4
uniprot id: W5N436
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:aqp9
gene id: 7918:aqp9
uniprot id: W5N7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

7918:nek6
gene id: 7918:nek6
uniprot id: W5MD46
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:agpat3
gene id: 7918:agpat3
uniprot id: W5M7Z6
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

7918:slc6a1
gene id: 7918:slc6a1
uniprot id: W5N949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

7918:dpy30
gene id: 7918:dpy30
uniprot id: W5NG75
names: Similarity
messages: Belongs to the dpy-30 family.

7918:pdlim3
gene id: 7918:pdlim3
uniprot id: W5N8S4
names: Subcellular Location Annotation
messages: Z line

7918:matk
gene id: 7918:matk
uniprot id: W5M8I0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:nsun6
gene id: 7918:nsun6
uniprot id: W5MY52
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:fam49a
gene id: 7918:fam49a
uniprot id: W5NI97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

7918:LOC102697332
gene id: 7918:LOC102697332
uniprot id: W5LXU5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

7918:ugp2
gene id: 7918:ugp2
uniprot id: W5NGN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

7918:pex6
gene id: 7918:pex6
uniprot id: W5NEY3
names: Subcellular Location Annotation
messages: cytosol

7918:LOC102683435
gene id: 7918:LOC102683435
uniprot id: W5MQ45
names: Similarity
messages: Belongs to the TRIM/RBCC family.

7918:plbd2
gene id: 7918:plbd2
uniprot id: W5MNZ0
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

7918:LOC102683986
gene id: 7918:LOC102683986
uniprot id: W5N9D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:emc8
gene id: 7918:emc8
uniprot id: W5LY47
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

7918:LOC102687846
gene id: 7918:LOC102687846
uniprot id: W5MN44
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

7918:slc16a9
gene id: 7918:slc16a9
uniprot id: W5MHY3
names: Subcellular Location Annotation
messages: Membrane

7918:paics
gene id: 7918:paics
uniprot id: W5N9F1
names: Similarity
names: Subunit
messages: Homooctamer.
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
messages: In the N-terminal section; belongs to the SAICAR synthetase family.

7918:tamm41
gene id: 7918:tamm41
uniprot id: W5N967
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

7918:murc
gene id: 7918:murc
uniprot id: W5N4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

7918:jph2
gene id: 7918:jph2
uniprot id: W5M1U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

7918:LOC102694391
gene id: 7918:LOC102694391
uniprot id: W5MHR0
names: Similarity
messages: Belongs to the MS4A family.

7918:eps8
gene id: 7918:eps8
uniprot id: W5NI99
names: Similarity
messages: Belongs to the EPS8 family.

7918:fam83b
gene id: 7918:fam83b
uniprot id: W5NJT6
names: Similarity
messages: Belongs to the FAM83 family.

7918:folh1b
gene id: 7918:folh1b
uniprot id: W5MK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

7918:arl11
gene id: 7918:arl11
uniprot id: W5NMP5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

7918:timp4
gene id: 7918:timp4
uniprot id: W5N987
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

7918:nedd9
gene id: 7918:nedd9
uniprot id: W5MMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

7918:gtf2b
gene id: 7918:gtf2b
uniprot id: W5MCI0
names: Similarity
messages: Belongs to the TFIIB family.

7918:prpf18
gene id: 7918:prpf18
uniprot id: W5NJ71
uniprot id: W5NJ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

7918:adamts19
gene id: 7918:adamts19
uniprot id: W5MNZ9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:LOC102689775
gene id: 7918:LOC102689775
uniprot id: W5MLI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

7918:galr2
gene id: 7918:galr2
uniprot id: W5N635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

7918:tpd52
gene id: 7918:tpd52
uniprot id: W5M4L7
names: Similarity
messages: Belongs to the TPD52 family.

7918:LOC102691800
gene id: 7918:LOC102691800
uniprot id: W5MDG3
names: Similarity
messages: Belongs to the peptidase C1 family.

7918:hexb
gene id: 7918:hexb
uniprot id: W5MYR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

7918:lox
gene id: 7918:lox
uniprot id: W5MQJ5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

7918:dok1
gene id: 7918:dok1
uniprot id: W5LZS0
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

7918:npepl1
gene id: 7918:npepl1
uniprot id: W5MGL2
names: Similarity
messages: Belongs to the peptidase M17 family.

7918:LOC102695530
gene id: 7918:LOC102695530
uniprot id: W5MWH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

7918:hsd17b7
gene id: 7918:hsd17b7
uniprot id: W5MJR5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

7918:hhex
gene id: 7918:hhex
uniprot id: W5MJJ1
names: Subcellular Location Annotation
messages: Nucleus

7918:clg2h9orf64
gene id: 7918:clg2h9orf64
uniprot id: W5M2L4
names: Function
names: Similarity
messages: Belongs to the QNG1 protein family.
messages: Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.

7918:irx5
gene id: 7918:irx5
uniprot id: W5MJP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

7918:tpd52l2
gene id: 7918:tpd52l2
uniprot id: W5MCU6
names: Similarity
messages: Belongs to the TPD52 family.

7918:fam3b
gene id: 7918:fam3b
uniprot id: W5LZT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

7918:ampd2
gene id: 7918:ampd2
uniprot id: W5N3K3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

7918:stmn2
gene id: 7918:stmn2
uniprot id: W5MB43
names: Similarity
messages: Belongs to the stathmin family.

7918:olfml2a
gene id: 7918:olfml2a
uniprot id: W5MCQ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:cnksr1
gene id: 7918:cnksr1
uniprot id: W5ME27
names: Similarity
messages: Belongs to the CNKSR family.

7918:glra1
gene id: 7918:glra1
uniprot id: W5N0Z5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

7918:tk2
gene id: 7918:tk2
uniprot id: W5MCQ7
names: Similarity
messages: Belongs to the DCK/DGK family.

7918:diexf
gene id: 7918:diexf
uniprot id: W5NKS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

7918:rgs9bp
gene id: 7918:rgs9bp
uniprot id: W5NM30
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

7918:chst13
gene id: 7918:chst13
uniprot id: W5N8H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:fam207a
gene id: 7918:fam207a
uniprot id: W5MRK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

7918:LOC102692054
gene id: 7918:LOC102692054
uniprot id: W5NHZ8
names: Similarity
messages: Belongs to the peptidase C2 family.

7918:mertk
gene id: 7918:mertk
uniprot id: W5NIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

7918:tspan31
gene id: 7918:tspan31
uniprot id: W5M8M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:fam134b
gene id: 7918:fam134b
uniprot id: W5N4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:LOC102693889
gene id: 7918:LOC102693889
uniprot id: W5MUD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

7918:LOC102688988
gene id: 7918:LOC102688988
uniprot id: W5MIR4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: desmosome

7918:arl6ip5
gene id: 7918:arl6ip5
uniprot id: W5MVE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

7918:LOC107079202
gene id: 7918:LOC107079202
uniprot id: W5MUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

7918:mettl10
gene id: 7918:mettl10
uniprot id: W5MMZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

7918:nhej1
gene id: 7918:nhej1
uniprot id: W5MY49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

7918:cul3
gene id: 7918:cul3
uniprot id: W5M8M2
names: Similarity
messages: Belongs to the cullin family.

7918:LOC102683391
gene id: 7918:LOC102683391
uniprot id: W5MTB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

7918:ndufb1
gene id: 7918:ndufb1
uniprot id: W5N9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

7918:slc24a1
gene id: 7918:slc24a1
uniprot id: W5N8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

7918:tsen54
gene id: 7918:tsen54
uniprot id: W5MZE2
names: Similarity
messages: Belongs to the SEN54 family.

7918:supv3l1
gene id: 7918:supv3l1
uniprot id: W5MS15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

7918:yars
gene id: 7918:yars
uniprot id: W5M2B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus

7918:tmem165
gene id: 7918:tmem165
uniprot id: W5N9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

7918:wnt7a
gene id: 7918:wnt7a
uniprot id: W5N9K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:LOC102684644
gene id: 7918:LOC102684644
uniprot id: W5MYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:orc2
gene id: 7918:orc2
uniprot id: W5MUG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

7918:LOC102691882
gene id: 7918:LOC102691882
uniprot id: W5N5M5
names: Subcellular Location Annotation
messages: Membrane

7918:gcnt1
gene id: 7918:gcnt1
uniprot id: W5NLY4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

7918:gdf6
gene id: 7918:gdf6
uniprot id: W5M4Z8
names: Similarity
messages: Belongs to the TGF-beta family.

7918:fgb
gene id: 7918:fgb
uniprot id: W5MP92
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

7918:uckl1
gene id: 7918:uckl1
uniprot id: W5MBZ5
uniprot id: W5MC09
names: Similarity
messages: Belongs to the uridine kinase family.

7918:ergic2
gene id: 7918:ergic2
uniprot id: W5ND93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

7918:LOC102686825
gene id: 7918:LOC102686825
uniprot id: W5NGA5
names: Subcellular Location Annotation
messages: Membrane

7918:rtn4ip1
gene id: 7918:rtn4ip1
uniprot id: W5NIL9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

7918:lamtor2
gene id: 7918:lamtor2
uniprot id: W5MR11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

7918:cdv3
gene id: 7918:cdv3
uniprot id: W5N2I1
names: Similarity
messages: Belongs to the CDV3 family.

7918:sgsh
gene id: 7918:sgsh
uniprot id: W5N480
names: Similarity
messages: Belongs to the sulfatase family.

7918:LOC102697453
gene id: 7918:LOC102697453
uniprot id: W5MQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:stoml2
gene id: 7918:stoml2
uniprot id: W5MA90
names: Similarity
messages: Belongs to the band 7/mec-2 family.

7918:rapgef6
gene id: 7918:rapgef6
uniprot id: W5MW49
names: Similarity
messages: Belongs to the RAPGEF2 family.

7918:myo9b
gene id: 7918:myo9b
uniprot id: W5M997
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

7918:tub
gene id: 7918:tub
uniprot id: W5M618
uniprot id: W5M628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

7918:bmp1
gene id: 7918:bmp1
uniprot id: W5NCL2
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:mrpl17
gene id: 7918:mrpl17
uniprot id: W5MA92
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

7918:epc2
gene id: 7918:epc2
uniprot id: W5LZV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

7918:p2rx5
gene id: 7918:p2rx5
uniprot id: W5M6K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

7918:bmp10
gene id: 7918:bmp10
uniprot id: W5NE19
names: Similarity
messages: Belongs to the TGF-beta family.

7918:antxr2
gene id: 7918:antxr2
uniprot id: W5MK56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

7918:LOC102687908
gene id: 7918:LOC102687908
uniprot id: W5MIL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

7918:bnip3
gene id: 7918:bnip3
uniprot id: W5ML71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

7918:cpeb3
gene id: 7918:cpeb3
uniprot id: W5MJS6
names: Similarity
messages: Belongs to the RRM CPEB family.

7918:slc6a6
gene id: 7918:slc6a6
uniprot id: W5N7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

7918:kcng4
gene id: 7918:kcng4
uniprot id: W5M2S0
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102689119
gene id: 7918:LOC102689119
uniprot id: W5NDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

7918:pknox1
gene id: 7918:pknox1
uniprot id: W5M8B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

7918:cebpz
gene id: 7918:cebpz
uniprot id: W5NJP2
names: Similarity
messages: Belongs to the CBF/MAK21 family.

7918:ddx56
gene id: 7918:ddx56
uniprot id: W5NDH6
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

7918:msh2
gene id: 7918:msh2
uniprot id: W5NHL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

7918:zw10
gene id: 7918:zw10
uniprot id: W5MAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

7918:parn
gene id: 7918:parn
uniprot id: W5LXE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm

7918:ldhd
gene id: 7918:ldhd
uniprot id: W5M6C1
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

7918:arpc2
gene id: 7918:arpc2
uniprot id: W5MS34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

7918:unc5c
gene id: 7918:unc5c
uniprot id: W5N5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

7918:hat1
gene id: 7918:hat1
uniprot id: W5MLN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

7918:sptlc2
gene id: 7918:sptlc2
uniprot id: W5MQP1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

7918:mrpl41
gene id: 7918:mrpl41
uniprot id: W5NLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

7918:pde4b
gene id: 7918:pde4b
uniprot id: W5MJ19
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:slc30a8
gene id: 7918:slc30a8
uniprot id: W5M636
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

7918:zmynd10
gene id: 7918:zmynd10
uniprot id: W5NA72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ZMYND10 family.
messages: Dynein axonemal particle
messages: Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins.
messages: centriolar satellite

7918:hapln2
gene id: 7918:hapln2
uniprot id: W5MN99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:tp63
gene id: 7918:tp63
uniprot id: W5MCU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Nucleus

7918:e2f7
gene id: 7918:e2f7
uniprot id: W5NHH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

7918:stard6
gene id: 7918:stard6
uniprot id: W5M6N1
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

7918:tomm22
gene id: 7918:tomm22
uniprot id: W5N1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

7918:LOC102688248
gene id: 7918:LOC102688248
uniprot id: W5NCI7
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

7918:gjd2
gene id: 7918:gjd2
uniprot id: W5N2W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:mrps10
gene id: 7918:mrps10
uniprot id: W5NL13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

7918:parp1
gene id: 7918:parp1
uniprot id: W5NFP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.

7918:chrm1
gene id: 7918:chrm1
uniprot id: W5NM59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

7918:LOC102688225
gene id: 7918:LOC102688225
uniprot id: W5N5U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:chst3
gene id: 7918:chst3
uniprot id: W5ME72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

7918:LOC102692094
gene id: 7918:LOC102692094
uniprot id: W5MS12
names: Similarity
messages: Belongs to the intermediate filament family.

7918:tfeb
gene id: 7918:tfeb
uniprot id: W5N2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

7918:sidt1
gene id: 7918:sidt1
uniprot id: W5M504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

7918:fam129c
gene id: 7918:fam129c
uniprot id: W5MPV1
names: Similarity
messages: Belongs to the Niban family.

7918:spi1
gene id: 7918:spi1
uniprot id: W5MGN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:tekt3
gene id: 7918:tekt3
uniprot id: W5N6C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

7918:fzd3
gene id: 7918:fzd3
uniprot id: W5NGI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:st6gal2
gene id: 7918:st6gal2
uniprot id: W5MQU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:grik3
gene id: 7918:grik3
uniprot id: W5M5Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

7918:ap3m2
gene id: 7918:ap3m2
uniprot id: W5NF04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

7918:bcl7b
gene id: 7918:bcl7b
uniprot id: W5LYI7
names: Similarity
messages: Belongs to the BCL7 family.

7918:LOC102690822
gene id: 7918:LOC102690822
uniprot id: W5MD82
names: Subcellular Location Annotation
messages: Cytoplasm

7918:tubgcp4
gene id: 7918:tubgcp4
uniprot id: W5NA20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

7918:fat2
gene id: 7918:fat2
uniprot id: W5N170
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:stx4
gene id: 7918:stx4
uniprot id: W5M4P4
names: Similarity
messages: Belongs to the syntaxin family.

7918:pex10
gene id: 7918:pex10
uniprot id: W5MEJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Membrane
messages: Peroxisome membrane

7918:hras
gene id: 7918:hras
uniprot id: W5LXA0
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:slc20a2
gene id: 7918:slc20a2
uniprot id: W5MZV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

7918:trpc6
gene id: 7918:trpc6
uniprot id: W5MEA1
names: Subcellular Location Annotation
messages: Membrane

7918:dpp7
gene id: 7918:dpp7
uniprot id: W5M003
names: Similarity
messages: Belongs to the peptidase S28 family.

7918:pla2g12a
gene id: 7918:pla2g12a
uniprot id: W5N375
names: Subcellular Location Annotation
messages: Secreted

7918:erbb2
gene id: 7918:erbb2
uniprot id: W5N4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

7918:slco2b1
gene id: 7918:slco2b1
uniprot id: W5MY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

7918:pgc
gene id: 7918:pgc
uniprot id: W5N4U3
names: Similarity
messages: Belongs to the peptidase A1 family.

7918:tm7sf3
gene id: 7918:tm7sf3
uniprot id: W5NDL2
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102697879
gene id: 7918:LOC102697879
uniprot id: W5N660
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:rpl3l
gene id: 7918:rpl3l
uniprot id: W5MR39
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

7918:insm1
gene id: 7918:insm1
uniprot id: W5NNA1
names: Subcellular Location Annotation
messages: Nucleus

7918:sdpr
gene id: 7918:sdpr
uniprot id: W5MCQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

7918:mab21l3
gene id: 7918:mab21l3
uniprot id: W5MZL0
names: Similarity
messages: Belongs to the mab-21 family.

7918:LOC102693301
gene id: 7918:LOC102693301
uniprot id: W5NN04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

7918:clg2h18orf32
gene id: 7918:clg2h18orf32
uniprot id: W5N121
names: Similarity
messages: Belongs to the UPF0729 family.

7918:ngfr
gene id: 7918:ngfr
uniprot id: W5N119
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102686600
gene id: 7918:LOC102686600
uniprot id: W5N5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

7918:pcmtd2
gene id: 7918:pcmtd2
uniprot id: W5MD24
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

7918:clg5h10orf53
gene id: 7918:clg5h10orf53
uniprot id: W5MEQ8
names: Similarity
messages: Belongs to the UPF0728 family.

7918:arid1a
gene id: 7918:arid1a
uniprot id: W5M835
names: Subcellular Location Annotation
messages: Nucleus

7918:mycbp
gene id: 7918:mycbp
uniprot id: W5MEZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

7918:gins2
gene id: 7918:gins2
uniprot id: W5LY21
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

7918:tnfsf11
gene id: 7918:tnfsf11
uniprot id: W5MEX9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

7918:adamts15
gene id: 7918:adamts15
uniprot id: W5M9N9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:LOC102693044
gene id: 7918:LOC102693044
uniprot id: W5NIC3
names: Subcellular Location Annotation
messages: Membrane

7918:inpp5a
gene id: 7918:inpp5a
uniprot id: W5MKU3
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

7918:camk1g
gene id: 7918:camk1g
uniprot id: W5N003
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:tmco1
gene id: 7918:tmco1
uniprot id: W5MG20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:lin52
gene id: 7918:lin52
uniprot id: W5MYE2
names: Similarity
messages: Belongs to the lin-52 family.

7918:mc5r
gene id: 7918:mc5r
uniprot id: W5NP82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

7918:ttc39b
gene id: 7918:ttc39b
uniprot id: W5N1Q4
names: Similarity
messages: Belongs to the TTC39 family.

7918:phf19
gene id: 7918:phf19
uniprot id: W5MHA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

7918:brd1
gene id: 7918:brd1
uniprot id: W5NGK8
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102684216
gene id: 7918:LOC102684216
uniprot id: W5MZL6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

7918:ss18l1
gene id: 7918:ss18l1
uniprot id: W5M7R6
names: Similarity
messages: Belongs to the SS18 family.

7918:dcc
gene id: 7918:dcc
uniprot id: W5M6E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

7918:aplp2
gene id: 7918:aplp2
uniprot id: W5LYJ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:prpf4b
gene id: 7918:prpf4b
uniprot id: W5N2S6
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

7918:slc16a2
gene id: 7918:slc16a2
uniprot id: W5N858
names: Subcellular Location Annotation
messages: Membrane

7918:ubr2
gene id: 7918:ubr2
uniprot id: W5NIB6
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

7918:LOC102694387
gene id: 7918:LOC102694387
uniprot id: W5NNR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

7918:clg7hxorf56
gene id: 7918:clg7hxorf56
uniprot id: W5NBU3
names: Similarity
messages: Belongs to the STEEP1 family.

7918:gpr156
gene id: 7918:gpr156
uniprot id: W5MJD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:LOC102688843
gene id: 7918:LOC102688843
uniprot id: W5N5W9
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

7918:sfr1
gene id: 7918:sfr1
uniprot id: W5N1W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

7918:stxbp5
gene id: 7918:stxbp5
uniprot id: W5NGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

7918:thap1
gene id: 7918:thap1
uniprot id: W5M612
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

7918:mmp2
gene id: 7918:mmp2
uniprot id: W5MJL2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: extracellular matrix

7918:rps17
gene id: 7918:rps17
uniprot id: W5NCV6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

7918:fgf1
gene id: 7918:fgf1
uniprot id: W5MX08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

7918:wasf2
gene id: 7918:wasf2
uniprot id: W5MB33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

7918:LOC102692865
gene id: 7918:LOC102692865
uniprot id: W5NKJ8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

7918:tle1
gene id: 7918:tle1
uniprot id: W5MUT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

7918:fam72a
gene id: 7918:fam72a
uniprot id: W5N2W3
names: Similarity
messages: Belongs to the FAM72 family.

7918:llgl1
gene id: 7918:llgl1
uniprot id: W5MC81
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

7918:fbxo9
gene id: 7918:fbxo9
uniprot id: W5NJQ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9).
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and acts as a regulator of mTOR signaling.

7918:LOC102687756
gene id: 7918:LOC102687756
uniprot id: W5N8G7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

7918:rnmt
gene id: 7918:rnmt
uniprot id: W5MTE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

7918:lhx8
gene id: 7918:lhx8
uniprot id: W5M6T0
names: Subcellular Location Annotation
messages: Nucleus

7918:fgd5
gene id: 7918:fgd5
uniprot id: W5MZ81
names: Subcellular Location Annotation
messages: cytoskeleton

7918:ssr1
gene id: 7918:ssr1
uniprot id: W5N197
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-alpha family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

7918:atp2c1
gene id: 7918:atp2c1
uniprot id: W5M0B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:b3gnt8
gene id: 7918:b3gnt8
uniprot id: W5NM08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:sfxn4
gene id: 7918:sfxn4
uniprot id: W5MU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

7918:fam46c
gene id: 7918:fam46c
uniprot id: W5NMQ1
names: Similarity
messages: Belongs to the TENT family.

7918:dclk2
gene id: 7918:dclk2
uniprot id: W5MQ78
uniprot id: W5MQ89
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

7918:tshz3
gene id: 7918:tshz3
uniprot id: W5MEY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

7918:LOC102699180
gene id: 7918:LOC102699180
uniprot id: W5MHD5
names: Subcellular Location Annotation
messages: Cytoplasm

7918:LOC102689647
gene id: 7918:LOC102689647
uniprot id: W5NE55
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102697516
gene id: 7918:LOC102697516
uniprot id: W5MQ79
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

7918:rps6ka3
gene id: 7918:rps6ka3
uniprot id: W5M7H5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

7918:paqr3
gene id: 7918:paqr3
uniprot id: W5MKG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

7918:prosc
gene id: 7918:prosc
uniprot id: W5NF62
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

7918:sfmbt2
gene id: 7918:sfmbt2
uniprot id: W5NF79
names: Subcellular Location Annotation
messages: Nucleus

7918:mgrn1
gene id: 7918:mgrn1
uniprot id: W5MLJ8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

7918:LOC102689744
gene id: 7918:LOC102689744
uniprot id: W5N5E9
names: Similarity
messages: Belongs to the IL-6 superfamily.

7918:LOC102698131
gene id: 7918:LOC102698131
uniprot id: W5ND39
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

7918:LOC102692485
gene id: 7918:LOC102692485
uniprot id: W5NLU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:chuk
gene id: 7918:chuk
uniprot id: W5MAB2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:snx10
gene id: 7918:snx10
uniprot id: W5N1H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

7918:aarsd1
gene id: 7918:aarsd1
uniprot id: W5N331
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

7918:arid5b
gene id: 7918:arid5b
uniprot id: W5MIL2
names: Similarity
messages: Belongs to the ARID5B family.

7918:LOC102691663
gene id: 7918:LOC102691663
uniprot id: W5N3K9
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

7918:mcoln2
gene id: 7918:mcoln2
uniprot id: W5ME71
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

7918:LOC102697165
gene id: 7918:LOC102697165
uniprot id: W5MRC9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

7918:myo3b
gene id: 7918:myo3b
uniprot id: W5MMG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

7918:fam188a
gene id: 7918:fam188a
uniprot id: W5MWT9
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

7918:kiaa1324
gene id: 7918:kiaa1324
uniprot id: W5MVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

7918:LOC102690904
gene id: 7918:LOC102690904
uniprot id: W5M1Y0
names: Subcellular Location Annotation
messages: Membrane

7918:gpr37
gene id: 7918:gpr37
uniprot id: W5NFW2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:lpar2
gene id: 7918:lpar2
uniprot id: W5MIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

7918:rora
gene id: 7918:rora
uniprot id: W5NC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:pcyt1b
gene id: 7918:pcyt1b
uniprot id: W5M146
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

7918:acss3
gene id: 7918:acss3
uniprot id: W5NHL9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

7918:dcstamp
gene id: 7918:dcstamp
uniprot id: W5MT47
names: Subcellular Location Annotation
messages: Membrane

7918:tmem182
gene id: 7918:tmem182
uniprot id: W5MQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

7918:anxa5
gene id: 7918:anxa5
uniprot id: W5M5C4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

7918:LOC102691296
gene id: 7918:LOC102691296
uniprot id: M1ZMJ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

7918:fam19a2
gene id: 7918:fam19a2
uniprot id: W5NI47
names: Similarity
messages: Belongs to the TAFA family.

7918:ism2
gene id: 7918:ism2
uniprot id: W5MQM7
names: Similarity
messages: Belongs to the isthmin family.

7918:zfyve27
gene id: 7918:zfyve27
uniprot id: W5MR19
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

7918:tln1
gene id: 7918:tln1
uniprot id: W5MYM4
names: Subcellular Location Annotation
messages: cytoskeleton

7918:ptprn
gene id: 7918:ptprn
uniprot id: W5MXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

7918:mut
gene id: 7918:mut
uniprot id: W5NIT4
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

7918:tmem255b
gene id: 7918:tmem255b
uniprot id: W5MUU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

7918:slc25a40
gene id: 7918:slc25a40
uniprot id: W5MWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:mrpl37
gene id: 7918:mrpl37
uniprot id: W5M656
names: Subcellular Location Annotation
messages: Mitochondrion

7918:bbs5
gene id: 7918:bbs5
uniprot id: W5MN19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: centriolar satellite
messages: cilium membrane

7918:naa40
gene id: 7918:naa40
uniprot id: W5M159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

7918:cs
gene id: 7918:cs
uniprot id: W5MB20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

7918:slc25a29
gene id: 7918:slc25a29
uniprot id: W5N0W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:slc35f4
gene id: 7918:slc35f4
uniprot id: W5MZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

7918:cfap36
gene id: 7918:cfap36
uniprot id: W5NE64
names: Similarity
messages: Belongs to the CFAP36 family.

7918:manba
gene id: 7918:manba
uniprot id: W5N2J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

7918:LOC102697984
gene id: 7918:LOC102697984
uniprot id: W5MIJ6
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

7918:gnpda2
gene id: 7918:gnpda2
uniprot id: W5N3R5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

7918:cacng2
gene id: 7918:cacng2
uniprot id: W5MZJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

7918:glce
gene id: 7918:glce
uniprot id: W5N9C7
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

7918:LOC102694640
gene id: 7918:LOC102694640
uniprot id: W5NLD2
names: Similarity
messages: Belongs to the glycosyltransferase 92 family.

7918:chi3l2
gene id: 7918:chi3l2
uniprot id: W5N1J0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

7918:LOC102688551
gene id: 7918:LOC102688551
uniprot id: W5NAT4
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

7918:LOC107077033
gene id: 7918:LOC107077033
uniprot id: W5MD98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

7918:gucy2f
gene id: 7918:gucy2f
uniprot id: W5NAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

7918:LOC102697842
gene id: 7918:LOC102697842
uniprot id: W5MLY4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

7918:cand1
gene id: 7918:cand1
uniprot id: W5NH16
names: Similarity
messages: Belongs to the CAND family.

7918:ogfod1
gene id: 7918:ogfod1
uniprot id: W5MMU6
names: Similarity
messages: Belongs to the TPA1 family.

7918:epha8
gene id: 7918:epha8
uniprot id: W5LXN4
names: Subcellular Location Annotation
messages: Membrane

7918:reep3
gene id: 7918:reep3
uniprot id: W5MIZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

7918:ttc39c
gene id: 7918:ttc39c
uniprot id: W5MHN2
names: Similarity
messages: Belongs to the TTC39 family.

7918:adcyap1r1
gene id: 7918:adcyap1r1
uniprot id: W5MTG6
names: Subcellular Location Annotation
messages: Membrane

7918:gipc1
gene id: 7918:gipc1
uniprot id: W5MUT0
names: Similarity
messages: Belongs to the GIPC family.

7918:stat3
gene id: 7918:stat3
uniprot id: W5N463
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

7918:ppp3r1
gene id: 7918:ppp3r1
uniprot id: W5NGG8
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

7918:ippk
gene id: 7918:ippk
uniprot id: W5N8V5
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

7918:LOC102689654
gene id: 7918:LOC102689654
uniprot id: W5N640
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

7918:esyt3
gene id: 7918:esyt3
uniprot id: W5M6F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:pdgfd
gene id: 7918:pdgfd
uniprot id: W5MJD4
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:avpr1a
gene id: 7918:avpr1a
uniprot id: W5NK33
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:unc5d
gene id: 7918:unc5d
uniprot id: W5NDA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

7918:samd4a
gene id: 7918:samd4a
uniprot id: W5N2P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

7918:nppc
gene id: 7918:nppc
uniprot id: W5MBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

7918:rps2
gene id: 7918:rps2
uniprot id: W5MR12
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

7918:adrb1
gene id: 7918:adrb1
uniprot id: W5NNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:gpr65
gene id: 7918:gpr65
uniprot id: W5MPM5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:acsf3
gene id: 7918:acsf3
uniprot id: W5MB12
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

7918:LOC102697133
gene id: 7918:LOC102697133
uniprot id: W5NBS0
names: Similarity
messages: Belongs to the MDFI family.

7918:rpl27
gene id: 7918:rpl27
uniprot id: W5N347
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

7918:LOC102698548
gene id: 7918:LOC102698548
uniprot id: W5NP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:LOC102689754
gene id: 7918:LOC102689754
uniprot id: W5M5J7
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

7918:hipk4
gene id: 7918:hipk4
uniprot id: W5NC79
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:mov10
gene id: 7918:mov10
uniprot id: W5MW54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

7918:hsbp1
gene id: 7918:hsbp1
uniprot id: W5M2N7
names: Similarity
messages: Belongs to the HSBP1 family.

7918:ap5m1
gene id: 7918:ap5m1
uniprot id: W5MZ91
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

7918:pusl1
gene id: 7918:pusl1
uniprot id: W5M2I8
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

7918:mvb12b
gene id: 7918:mvb12b
uniprot id: W5LZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

7918:mrm1
gene id: 7918:mrm1
uniprot id: W5MC38
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

7918:nim1k
gene id: 7918:nim1k
uniprot id: W5MNB0
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:tmem147
gene id: 7918:tmem147
uniprot id: W5M711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM147 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:slc4a3
gene id: 7918:slc4a3
uniprot id: W5MSB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:trpc1
gene id: 7918:trpc1
uniprot id: W5MMH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

7918:ndufs3
gene id: 7918:ndufs3
uniprot id: W5MFZ6
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

7918:fam19a4
gene id: 7918:fam19a4
uniprot id: W5MVK2
names: Similarity
messages: Belongs to the TAFA family.

7918:spcs1
gene id: 7918:spcs1
uniprot id: W5MWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:ndufa8
gene id: 7918:ndufa8
uniprot id: W5M514
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

7918:acaa1
gene id: 7918:acaa1
uniprot id: W5MU79
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

7918:nudt12
gene id: 7918:nudt12
uniprot id: W5MRZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

7918:tll1
gene id: 7918:tll1
uniprot id: W5M705
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:cnot6l
gene id: 7918:cnot6l
uniprot id: W5MKU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

7918:gk5
gene id: 7918:gk5
uniprot id: W5MMV1
names: Similarity
messages: Belongs to the FGGY kinase family.

7918:LOC102698039
gene id: 7918:LOC102698039
uniprot id: W5M228
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:kif11
gene id: 7918:kif11
uniprot id: W5MJL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
messages: spindle pole

7918:prlr
gene id: 7918:prlr
uniprot id: W5N1M6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

7918:syngr3
gene id: 7918:syngr3
uniprot id: W5MFY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

7918:olfml2b
gene id: 7918:olfml2b
uniprot id: W5LZ58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102689180
gene id: 7918:LOC102689180
uniprot id: W5N307
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

7918:lmod3
gene id: 7918:lmod3
uniprot id: W5MVC2
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

7918:ldlrad4
gene id: 7918:ldlrad4
uniprot id: W5MTI2
uniprot id: W5MTJ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:etv6
gene id: 7918:etv6
uniprot id: W5NI56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:LOC102682740
gene id: 7918:LOC102682740
uniprot id: W5NLM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:clg17hxorf36
gene id: 7918:clg17hxorf36
uniprot id: W5M112
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

7918:psmc5
gene id: 7918:psmc5
uniprot id: W5N296
names: Similarity
messages: Belongs to the AAA ATPase family.

7918:plac8
gene id: 7918:plac8
uniprot id: W5MXE4
names: Similarity
messages: Belongs to the cornifelin family.

7918:slc2a12
gene id: 7918:slc2a12
uniprot id: W5NHA1
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

7918:nipa2
gene id: 7918:nipa2
uniprot id: W5MNK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

7918:gkap1
gene id: 7918:gkap1
uniprot id: W5M2G5
names: Similarity
messages: Belongs to the GKAP1 family.

7918:xpr1
gene id: 7918:xpr1
uniprot id: W5MUH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

7918:adcy1
gene id: 7918:adcy1
uniprot id: W5N677
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

7918:hibadh
gene id: 7918:hibadh
uniprot id: W5N1T5
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

7918:LOC107075873
gene id: 7918:LOC107075873
uniprot id: W5LWX9
names: Similarity
messages: Belongs to the TMEM121 family.

7918:cnih4
gene id: 7918:cnih4
uniprot id: W5NFQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

7918:mrps24
gene id: 7918:mrps24
uniprot id: W5NDX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

7918:LOC102688014
gene id: 7918:LOC102688014
uniprot id: W5NE17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Membrane

7918:itpk1
gene id: 7918:itpk1
uniprot id: W5N673
names: Similarity
messages: Belongs to the ITPK1 family.

7918:eif6
gene id: 7918:eif6
uniprot id: W5MM18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

7918:LOC102689714
gene id: 7918:LOC102689714
uniprot id: W5N2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

7918:plxnd1
gene id: 7918:plxnd1
uniprot id: W5N5Z3
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:cwc15
gene id: 7918:cwc15
uniprot id: W5MLC8
names: Similarity
messages: Belongs to the CWC15 family.

7918:tlr9
gene id: 7918:tlr9
uniprot id: W5NA34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

7918:LOC102682585
gene id: 7918:LOC102682585
uniprot id: W5MJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:agtr1
gene id: 7918:agtr1
uniprot id: W5NLK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

7918:ostc
gene id: 7918:ostc
uniprot id: W5MZH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

7918:csta
gene id: 7918:csta
uniprot id: W5M5Y7
names: Similarity
messages: Belongs to the cystatin family.

7918:polr2d
gene id: 7918:polr2d
uniprot id: W5MRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

7918:pax1
gene id: 7918:pax1
uniprot id: W5NJP6
names: Subcellular Location Annotation
messages: Nucleus

7918:spty2d1
gene id: 7918:spty2d1
uniprot id: W5M1E4
names: Similarity
messages: Belongs to the SPT2 family.

7918:rbpms2
gene id: 7918:rbpms2
uniprot id: W5NCX9
names: Subcellular Location Annotation
messages: Cytoplasm

7918:setd6
gene id: 7918:setd6
uniprot id: W5MGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

7918:wdr44
gene id: 7918:wdr44
uniprot id: W5NEA5
names: Subcellular Location Annotation
messages: trans-Golgi network

7918:LOC102686537
gene id: 7918:LOC102686537
uniprot id: W5MRT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:stx1b
gene id: 7918:stx1b
uniprot id: W5M4S1
names: Similarity
messages: Belongs to the syntaxin family.

7918:LOC102698357
gene id: 7918:LOC102698357
uniprot id: W5MNJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

7918:spx
gene id: 7918:spx
uniprot id: W5NE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

7918:cd79b
gene id: 7918:cd79b
uniprot id: W5N6I8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:LOC102683350
gene id: 7918:LOC102683350
uniprot id: W5NLN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

7918:LOC102691530
gene id: 7918:LOC102691530
uniprot id: W5N2Q6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

7918:LOC102682246
gene id: 7918:LOC102682246
uniprot id: W5MVX6
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

7918:tbce
gene id: 7918:tbce
uniprot id: W5NG15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCE family.
messages: Cytoplasm

7918:mef2a
gene id: 7918:mef2a
uniprot id: W5NAT5
uniprot id: W5NAT7
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102689759
gene id: 7918:LOC102689759
uniprot id: W5MNP3
names: Similarity
messages: Belongs to the HARBI1 family.

7918:LOC102683359
gene id: 7918:LOC102683359
uniprot id: W5NDQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

7918:nop58
gene id: 7918:nop58
uniprot id: W5MVW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

7918:slc7a4
gene id: 7918:slc7a4
uniprot id: W5MNM9
names: Subcellular Location Annotation
messages: Membrane

7918:tlcd2
gene id: 7918:tlcd2
uniprot id: W5MAG8
names: Subcellular Location Annotation
messages: Membrane

7918:smpd2
gene id: 7918:smpd2
uniprot id: W5MU44
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

7918:LOC102695285
gene id: 7918:LOC102695285
uniprot id: W5MXJ1
names: Similarity
messages: Belongs to the peptidase S51 family.

7918:cxcr5
gene id: 7918:cxcr5
uniprot id: W5LXM4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:mon1b
gene id: 7918:mon1b
uniprot id: W5NB46
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

7918:kcnc2
gene id: 7918:kcnc2
uniprot id: W5NHD5
names: Subcellular Location Annotation
messages: Membrane

7918:eif3h
gene id: 7918:eif3h
uniprot id: W5M698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

7918:ephb3
gene id: 7918:ephb3
uniprot id: W5MQ37
names: Subcellular Location Annotation
messages: Membrane

7918:cdc6
gene id: 7918:cdc6
uniprot id: W5N7U1
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

7918:znf703
gene id: 7918:znf703
uniprot id: W5NE16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

7918:hm13
gene id: 7918:hm13
uniprot id: W5M941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

7918:LOC102691301
gene id: 7918:LOC102691301
uniprot id: W5N3C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

7918:uck2
gene id: 7918:uck2
uniprot id: W5MG43
names: Similarity
messages: Belongs to the uridine kinase family.

7918:acadsb
gene id: 7918:acadsb
uniprot id: W5MNL8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

7918:plcd3
gene id: 7918:plcd3
uniprot id: W5N0K4
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

7918:stmn1
gene id: 7918:stmn1
uniprot id: W5M798
names: Similarity
messages: Belongs to the stathmin family.

7918:sstr2
gene id: 7918:sstr2
uniprot id: W5NMK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

7918:ncoa7
gene id: 7918:ncoa7
uniprot id: W5NIF3
names: Similarity
messages: Belongs to the OXR1 family.

7918:mstn
gene id: 7918:mstn
uniprot id: W5MQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

7918:bax
gene id: 7918:bax
uniprot id: W5MCT6
names: Similarity
messages: Belongs to the Bcl-2 family.

7918:tbl1xr1
gene id: 7918:tbl1xr1
uniprot id: W5LYJ3
names: Similarity
messages: Belongs to the WD repeat EBI family.

7918:cdc123
gene id: 7918:cdc123
uniprot id: W5NFD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

7918:LOC102684262
gene id: 7918:LOC102684262
uniprot id: W5MR05
names: Similarity
messages: Belongs to the tumor necrosis factor family.

7918:tada3
gene id: 7918:tada3
uniprot id: W5NBA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

7918:gdf11
gene id: 7918:gdf11
uniprot id: W5M7H2
names: Similarity
messages: Belongs to the TGF-beta family.

7918:LOC102694116
gene id: 7918:LOC102694116
uniprot id: W5MVE3
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

7918:copz2
gene id: 7918:copz2
uniprot id: W5N7B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

7918:tmem150b
gene id: 7918:tmem150b
uniprot id: W5N077
names: Subcellular Location Annotation
messages: Membrane

7918:nox1
gene id: 7918:nox1
uniprot id: W5NDX2
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102692611
gene id: 7918:LOC102692611
uniprot id: W5N0N7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:vgll2
gene id: 7918:vgll2
uniprot id: W5NKL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

7918:usp48
gene id: 7918:usp48
uniprot id: W5M0V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

7918:prrx1
gene id: 7918:prrx1
uniprot id: A0A075B5H8
uniprot id: W5VNG1
uniprot id: W5VP01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

7918:LOC102690200
gene id: 7918:LOC102690200
uniprot id: W5N8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:cyhr1
gene id: 7918:cyhr1
uniprot id: W5MF04
names: Similarity
messages: Belongs to the ZFTRAF1 family.

7918:panx3
gene id: 7918:panx3
uniprot id: W5MDI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

7918:soat1
gene id: 7918:soat1
uniprot id: W5MU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:LOC102683376
gene id: 7918:LOC102683376
uniprot id: W5MZA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:hoxa5
gene id: 7918:hoxa5
uniprot id: W5N1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

7918:aifm1
gene id: 7918:aifm1
uniprot id: W5NE37
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

7918:foxd1
gene id: 7918:foxd1
uniprot id: W5NLZ0
names: Subcellular Location Annotation
messages: Nucleus

7918:eif4e3
gene id: 7918:eif4e3
uniprot id: W5MV19
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

7918:top2a
gene id: 7918:top2a
uniprot id: W5N5J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.

7918:rap1a
gene id: 7918:rap1a
uniprot id: W5MWG6
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:psmd3
gene id: 7918:psmd3
uniprot id: W5N5G2
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

7918:rwdd3
gene id: 7918:rwdd3
uniprot id: W5MNL2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:fam96a
gene id: 7918:fam96a
uniprot id: W5N9L4
names: Similarity
messages: Belongs to the MIP18 family.

7918:LOC102696936
gene id: 7918:LOC102696936
uniprot id: W5M6P8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

7918:LOC107076807
gene id: 7918:LOC107076807
uniprot id: W5N1D9
names: Similarity
messages: Belongs to the peptidase A1 family.

7918:adck4
gene id: 7918:adck4
uniprot id: W5NB52
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

7918:nmu
gene id: 7918:nmu
uniprot id: W5N9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NmU family.
messages: Secreted

7918:eif2d
gene id: 7918:eif2d
uniprot id: W5N343
names: Similarity
messages: Belongs to the eIF2D family.

7918:hexim1
gene id: 7918:hexim1
uniprot id: W5NLV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

7918:chaf1b
gene id: 7918:chaf1b
uniprot id: W5MIT6
names: Subcellular Location Annotation
messages: Nucleus

7918:a1cf
gene id: 7918:a1cf
uniprot id: W5MGV1
names: Subcellular Location Annotation
messages: Cytoplasm

7918:galnt2
gene id: 7918:galnt2
uniprot id: W5NEG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:myo6
gene id: 7918:myo6
uniprot id: W5NJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus
messages: ruffle membrane
messages: trans-Golgi network membrane

7918:senp3
gene id: 7918:senp3
uniprot id: W5NB01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

7918:cfi
gene id: 7918:cfi
uniprot id: W5N354
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:myh10
gene id: 7918:myh10
uniprot id: W5N6P1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

7918:tmem115
gene id: 7918:tmem115
uniprot id: W5NA78
names: Subcellular Location Annotation
messages: Membrane

7918:cpxm2
gene id: 7918:cpxm2
uniprot id: W5MNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

7918:LOC102687507
gene id: 7918:LOC102687507
uniprot id: W5NFC6
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

7918:LOC102689826
gene id: 7918:LOC102689826
uniprot id: W5N154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

7918:LOC102687623
gene id: 7918:LOC102687623
uniprot id: W5NAL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

7918:six2
gene id: 7918:six2
uniprot id: W5NHV4
names: Subcellular Location Annotation
messages: Nucleus

7918:pkp1
gene id: 7918:pkp1
uniprot id: W5MUF2
names: Similarity
messages: Belongs to the beta-catenin family.

7918:LOC102689507
gene id: 7918:LOC102689507
uniprot id: W5NGT0
uniprot id: W5NGT1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

7918:aldh1a2
gene id: 7918:aldh1a2
uniprot id: W5N7Y5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

7918:fam69a
gene id: 7918:fam69a
uniprot id: W5MB21
names: Similarity
messages: Belongs to the DIPK family.

7918:b3gat1
gene id: 7918:b3gat1
uniprot id: W5M5A7
uniprot id: W5M5B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:tfdp2
gene id: 7918:tfdp2
uniprot id: W5MMW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

7918:LOC102685547
gene id: 7918:LOC102685547
uniprot id: W5MIY7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

7918:ccndbp1
gene id: 7918:ccndbp1
uniprot id: W5MJP6
names: Similarity
messages: Belongs to the CCNDBP1 family.

7918:snx33
gene id: 7918:snx33
uniprot id: W5NA88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

7918:rps23
gene id: 7918:rps23
uniprot id: W5N6V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Rough endoplasmic reticulum

7918:efna5
gene id: 7918:efna5
uniprot id: W5MS01
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:cstf3
gene id: 7918:cstf3
uniprot id: W5MA67
names: Subcellular Location Annotation
messages: Nucleus

7918:itgb4
gene id: 7918:itgb4
uniprot id: W5N0M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

7918:usp1
gene id: 7918:usp1
uniprot id: W5MHQ6
names: Similarity
messages: Belongs to the peptidase C19 family.

7918:mcur1
gene id: 7918:mcur1
uniprot id: W5N0K0
names: Similarity
messages: Belongs to the CCDC90 family.

7918:LOC102687009
gene id: 7918:LOC102687009
uniprot id: W5NAK5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

7918:cnn2
gene id: 7918:cnn2
uniprot id: W5M3L4
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

7918:drd3
gene id: 7918:drd3
uniprot id: W5M5T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:LOC102693995
gene id: 7918:LOC102693995
uniprot id: W5MZW6
names: Subcellular Location Annotation
messages: Secreted

7918:dusp12
gene id: 7918:dusp12
uniprot id: W5LZD2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

7918:mapk4
gene id: 7918:mapk4
uniprot id: W5N5A5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

7918:kcnmb4
gene id: 7918:kcnmb4
uniprot id: W5NH87
names: Subcellular Location Annotation
messages: Membrane

7918:kcnk3
gene id: 7918:kcnk3
uniprot id: W5NHX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

7918:LOC102689040
gene id: 7918:LOC102689040
uniprot id: W5N5Y0
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

7918:gins1
gene id: 7918:gins1
uniprot id: W5NJA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

7918:LOC102686597
gene id: 7918:LOC102686597
uniprot id: W5MJ23
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
messages: Belongs to the MoaD family. MOCS2A subfamily.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2B).
messages: cytosol

7918:epyc
gene id: 7918:epyc
uniprot id: W5NHX7
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

7918:jun
gene id: 7918:jun
uniprot id: W5NMJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

7918:LOC102688866
gene id: 7918:LOC102688866
uniprot id: W5MNI0
names: Similarity
messages: Belongs to the MS4A family.

7918:plpp3
gene id: 7918:plpp3
uniprot id: W5MQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

7918:plxna2
gene id: 7918:plxna2
uniprot id: W5MYH1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:LOC102688818
gene id: 7918:LOC102688818
uniprot id: W5MHF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:slc44a1
gene id: 7918:slc44a1
uniprot id: W5N0K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

7918:epha6
gene id: 7918:epha6
uniprot id: W5MWQ2
names: Subcellular Location Annotation
messages: Membrane

7918:sh2b2
gene id: 7918:sh2b2
uniprot id: W5M019
names: Similarity
messages: Belongs to the SH2B adapter family.

7918:ccnh
gene id: 7918:ccnh
uniprot id: W5M1F5
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

7918:parl
gene id: 7918:parl
uniprot id: W5MSN7
names: Subcellular Location Annotation
messages: Membrane

7918:polb
gene id: 7918:polb
uniprot id: W5NF22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

7918:fopnl
gene id: 7918:fopnl
uniprot id: W5MK61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

7918:chrdl1
gene id: 7918:chrdl1
uniprot id: W5N8S6
names: Subcellular Location Annotation
messages: Secreted

7918:nifk
gene id: 7918:nifk
uniprot id: W5M2A4
names: Subcellular Location Annotation
messages: nucleolus

7918:atp5l
gene id: 7918:atp5l
uniprot id: W5M8U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

7918:chac1
gene id: 7918:chac1
uniprot id: W5N3C4
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

7918:LOC102691911
gene id: 7918:LOC102691911
uniprot id: W5NMC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

7918:chmp6
gene id: 7918:chmp6
uniprot id: W5N5J6
names: Similarity
messages: Belongs to the SNF7 family.

7918:ric8a
gene id: 7918:ric8a
uniprot id: W5M379
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

7918:LOC102689968
gene id: 7918:LOC102689968
uniprot id: W5NCT2
names: Similarity
messages: Belongs to the actin family.

7918:sntb1
gene id: 7918:sntb1
uniprot id: W5MS96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

7918:LOC102697981
gene id: 7918:LOC102697981
uniprot id: W5MDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

7918:galt
gene id: 7918:galt
uniprot id: W5N3M7
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

7918:dmrta1
gene id: 7918:dmrta1
uniprot id: W5N4B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

7918:arhgef6
gene id: 7918:arhgef6
uniprot id: W5NDC3
names: Subcellular Location Annotation
messages: lamellipodium

7918:LOC102699131
gene id: 7918:LOC102699131
uniprot id: W5N089
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

7918:fbxo32
gene id: 7918:fbxo32
uniprot id: W5MV25
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102688085
gene id: 7918:LOC102688085
uniprot id: W5N338
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

7918:mipep
gene id: 7918:mipep
uniprot id: W5M0H9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

7918:foxe1
gene id: 7918:foxe1
uniprot id: W5NNE6
names: Subcellular Location Annotation
messages: Nucleus

7918:btg2
gene id: 7918:btg2
uniprot id: W5N011
names: Similarity
messages: Belongs to the BTG family.

7918:ngrn
gene id: 7918:ngrn
uniprot id: W5N3C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

7918:lsm1
gene id: 7918:lsm1
uniprot id: W5NDD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

7918:d2hgdh
gene id: 7918:d2hgdh
uniprot id: W5MI62
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

7918:mettl8
gene id: 7918:mettl8
uniprot id: W5MM05
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

7918:tmem14a
gene id: 7918:tmem14a
uniprot id: W5NJQ1
names: Similarity
messages: Belongs to the TMEM14 family.

7918:LOC102695578
gene id: 7918:LOC102695578
uniprot id: W5MYV4
names: Similarity
messages: Belongs to the TAFA family.

7918:hoxc5
gene id: 7918:hoxc5
uniprot id: W5MH21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

7918:tbpl1
gene id: 7918:tbpl1
uniprot id: W5NHA3
names: Similarity
messages: Belongs to the TBP family.

7918:upf2
gene id: 7918:upf2
uniprot id: W5NFB7
names: Subcellular Location Annotation
messages: Cytoplasm

7918:itga2b
gene id: 7918:itga2b
uniprot id: W5N6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

7918:cask
gene id: 7918:cask
uniprot id: W5M216
names: Similarity
messages: Belongs to the MAGUK family.

7918:diablo
gene id: 7918:diablo
uniprot id: W5MSS5
names: Subcellular Location Annotation
messages: Mitochondrion

7918:LOC102685814
gene id: 7918:LOC102685814
uniprot id: W5MMS9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

7918:igf2
gene id: 7918:igf2
uniprot id: W5M137
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

7918:tmem50b
gene id: 7918:tmem50b
uniprot id: W5M958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

7918:dkk2
gene id: 7918:dkk2
uniprot id: W5N4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

7918:hephl1
gene id: 7918:hephl1
uniprot id: W5ML02
names: Similarity
messages: Belongs to the multicopper oxidase family.

7918:nsun2
gene id: 7918:nsun2
uniprot id: W5MQK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: extracellular exosome

7918:gdi1
gene id: 7918:gdi1
uniprot id: W5NEJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

7918:LOC102682806
gene id: 7918:LOC102682806
uniprot id: W5M4Y5
names: Similarity
messages: Belongs to the intermediate filament family.

7918:mef2b
gene id: 7918:mef2b
uniprot id: W5MBL7
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102689801
gene id: 7918:LOC102689801
uniprot id: W5NCP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:cnn1
gene id: 7918:cnn1
uniprot id: W5MNF9
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

7918:adi1
gene id: 7918:adi1
uniprot id: W5NKX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

7918:mmp19
gene id: 7918:mmp19
uniprot id: W5M9J9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

7918:nt5c3a
gene id: 7918:nt5c3a
uniprot id: W5M3W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

7918:ptp4a2
gene id: 7918:ptp4a2
uniprot id: W5M0E4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

7918:glb1
gene id: 7918:glb1
uniprot id: W5LXP8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

7918:pdgfc
gene id: 7918:pdgfc
uniprot id: W5MNK0
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:dars
gene id: 7918:dars
uniprot id: W5LY06
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

7918:fubp1
gene id: 7918:fubp1
uniprot id: W5M7W4
names: Subcellular Location Annotation
messages: Nucleus

7918:chsy1
gene id: 7918:chsy1
uniprot id: W5N9N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

7918:LOC107077069
gene id: 7918:LOC107077069
uniprot id: W5MT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

7918:fam193b
gene id: 7918:fam193b
uniprot id: W5N253
names: Similarity
messages: Belongs to the FAM193 family.

7918:eci1
gene id: 7918:eci1
uniprot id: W5MHG1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

7918:asf1a
gene id: 7918:asf1a
uniprot id: W5MP83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

7918:tfap2e
gene id: 7918:tfap2e
uniprot id: W5LXF0
names: Similarity
messages: Belongs to the AP-2 family.

7918:zhx2
gene id: 7918:zhx2
uniprot id: W5NP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

7918:ifi35
gene id: 7918:ifi35
uniprot id: W5N365
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

7918:wdr35
gene id: 7918:wdr35
uniprot id: W5NKT8
names: Subcellular Location Annotation
messages: centrosome
messages: cilium basal body

7918:gemin2
gene id: 7918:gemin2
uniprot id: W5MS93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.

7918:rpl32
gene id: 7918:rpl32
uniprot id: W5N7Q5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

7918:slc13a1
gene id: 7918:slc13a1
uniprot id: W5NFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

7918:LOC102690809
gene id: 7918:LOC102690809
uniprot id: W5N8K7
uniprot id: W5N8L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:polr3d
gene id: 7918:polr3d
uniprot id: W5NGQ5
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102697324
gene id: 7918:LOC102697324
uniprot id: W5M2W7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:adgrd1
gene id: 7918:adgrd1
uniprot id: W5MGK2
names: Subcellular Location Annotation
messages: Membrane

7918:vat1l
gene id: 7918:vat1l
uniprot id: W5M8A6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

7918:dph6
gene id: 7918:dph6
uniprot id: W5N319
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

7918:cebpd
gene id: 7918:cebpd
uniprot id: W5NMR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

7918:tmem121
gene id: 7918:tmem121
uniprot id: W5NLS3
names: Similarity
messages: Belongs to the TMEM121 family.

7918:setd1b
gene id: 7918:setd1b
uniprot id: W5MCY9
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

7918:dusp3
gene id: 7918:dusp3
uniprot id: W5N2P5
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

7918:lzic
gene id: 7918:lzic
uniprot id: W5MIQ8
names: Similarity
messages: Belongs to the CTNNBIP1 family.

7918:nsmce4a
gene id: 7918:nsmce4a
uniprot id: W5MQN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

7918:fbxo25
gene id: 7918:fbxo25
uniprot id: W5NKZ8
uniprot id: W5NKZ9
names: Subcellular Location Annotation
messages: Nucleus

7918:znf706
gene id: 7918:znf706
uniprot id: W5MTU7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:prkce
gene id: 7918:prkce
uniprot id: W5NHU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

7918:mal2
gene id: 7918:mal2
uniprot id: W5MRU5
names: Subcellular Location Annotation
messages: Membrane

7918:zmpste24
gene id: 7918:zmpste24
uniprot id: W5MA06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

7918:nrdc
gene id: 7918:nrdc
uniprot id: W5MUK5
names: Similarity
messages: Belongs to the peptidase M16 family.

7918:LOC102694828
gene id: 7918:LOC102694828
uniprot id: W5MAL4
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

7918:smdt1
gene id: 7918:smdt1
uniprot id: W5N217
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

7918:polr2h
gene id: 7918:polr2h
uniprot id: W5MR91
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.

7918:tnip2
gene id: 7918:tnip2
uniprot id: W5N7T9
names: Subcellular Location Annotation
messages: Cytoplasm

7918:LOC102698253
gene id: 7918:LOC102698253
uniprot id: W5MKT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

7918:samd4b
gene id: 7918:samd4b
uniprot id: W5NBG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

7918:LOC102693901
gene id: 7918:LOC102693901
uniprot id: W5M761
uniprot id: W5M779
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

7918:LOC102694874
gene id: 7918:LOC102694874
uniprot id: W5MUL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

7918:LOC102689521
gene id: 7918:LOC102689521
uniprot id: W5MST4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:crebbp
gene id: 7918:crebbp
uniprot id: W5M482
names: Subcellular Location Annotation
messages: Cytoplasm

7918:vps29
gene id: 7918:vps29
uniprot id: W5MK92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

7918:acta1
gene id: 7918:acta1
uniprot id: W5NEI1
names: Similarity
messages: Belongs to the actin family.

7918:onecut1
gene id: 7918:onecut1
uniprot id: W5N7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

7918:LOC102683321
gene id: 7918:LOC102683321
uniprot id: W5NJM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

7918:slc10a6
gene id: 7918:slc10a6
uniprot id: W5M9F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

7918:LOC102690003
gene id: 7918:LOC102690003
uniprot id: W5NI60
names: Similarity
messages: Belongs to the ARTD/PARP family.

7918:ddx43
gene id: 7918:ddx43
uniprot id: W5NH17
names: Similarity
messages: Belongs to the DEAD box helicase family.

7918:slc13a5
gene id: 7918:slc13a5
uniprot id: W5MGV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

7918:svbp
gene id: 7918:svbp
uniprot id: W5LYP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

7918:LOC102696538
gene id: 7918:LOC102696538
uniprot id: W5NNN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

7918:nhsl2
gene id: 7918:nhsl2
uniprot id: W5NAW6
names: Similarity
messages: Belongs to the NHS family.

7918:gjc1
gene id: 7918:gjc1
uniprot id: W5NLV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:tyrp1
gene id: 7918:tyrp1
uniprot id: W5N6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

7918:LOC102697622
gene id: 7918:LOC102697622
uniprot id: W5NDS0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

7918:LOC102698082
gene id: 7918:LOC102698082
uniprot id: W5N2C2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:pepd
gene id: 7918:pepd
uniprot id: W5M1G9
names: Similarity
messages: Belongs to the peptidase M24B family.

7918:pou4f2
gene id: 7918:pou4f2
uniprot id: W5MQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

7918:hpse2
gene id: 7918:hpse2
uniprot id: W5MRQ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

7918:bgn
gene id: 7918:bgn
uniprot id: W5NEN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

7918:stag3
gene id: 7918:stag3
uniprot id: W5N691
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

7918:txk
gene id: 7918:txk
uniprot id: W5N266
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:txnip
gene id: 7918:txnip
uniprot id: W5MNM4
names: Similarity
messages: Belongs to the arrestin family.

7918:nfic
gene id: 7918:nfic
uniprot id: W5LZA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

7918:dusp6
gene id: 7918:dusp6
uniprot id: W5NHW7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

7918:nacc2
gene id: 7918:nacc2
uniprot id: W5M8D4
names: Subcellular Location Annotation
messages: Nucleus

7918:gba2
gene id: 7918:gba2
uniprot id: W5MT07
names: Function
names: Similarity
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

7918:kras
gene id: 7918:kras
uniprot id: W5NE07
uniprot id: W5NE08
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:tcf7l1
gene id: 7918:tcf7l1
uniprot id: W5ND38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

7918:cebpa
gene id: 7918:cebpa
uniprot id: W5NM32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

7918:tp53inp1
gene id: 7918:tp53inp1
uniprot id: W5MH15
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

7918:KEF94 p12
gene id: 7918:KEF94_p12
uniprot id: Q8HQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

7918:napg
gene id: 7918:napg
uniprot id: W5M306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane

7918:tp73
gene id: 7918:tp73
uniprot id: W5MD84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

7918:taf4
gene id: 7918:taf4
uniprot id: W5M7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

7918:LOC102697295
gene id: 7918:LOC102697295
uniprot id: W5MZ72
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

7918:LOC102684218
gene id: 7918:LOC102684218
uniprot id: W5N825
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

7918:chrd
gene id: 7918:chrd
uniprot id: W5MQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chordin family.
messages: Secreted

7918:apc
gene id: 7918:apc
uniprot id: W5MW81
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

7918:LOC102686129
gene id: 7918:LOC102686129
uniprot id: W5MRJ5
names: Subcellular Location Annotation
messages: Nucleus

7918:stk32c
gene id: 7918:stk32c
uniprot id: W5MKX9
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:LOC102687269
gene id: 7918:LOC102687269
uniprot id: W5NA02
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

7918:gpbp1l1
gene id: 7918:gpbp1l1
uniprot id: W5MFH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

7918:fam163a
gene id: 7918:fam163a
uniprot id: W5MRS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

7918:bmp4
gene id: 7918:bmp4
uniprot id: W5N2R3
names: Similarity
messages: Belongs to the TGF-beta family.

7918:LOC102693973
gene id: 7918:LOC102693973
uniprot id: W5M7V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

7918:mpv17
gene id: 7918:mpv17
uniprot id: W5NFX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

7918:LOC102682483
gene id: 7918:LOC102682483
uniprot id: W5NN87
names: Similarity
messages: Belongs to the syntaxin family.

7918:suclg1
gene id: 7918:suclg1
uniprot id: W5M3S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

7918:csf3r
gene id: 7918:csf3r
uniprot id: W5M5V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

7918:LOC102693624
gene id: 7918:LOC102693624
uniprot id: W5NFW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

7918:pou3f3
gene id: 7918:pou3f3
uniprot id: W5MQE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

7918:csnk1g1
gene id: 7918:csnk1g1
uniprot id: W5NCV9
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

7918:wnt9a
gene id: 7918:wnt9a
uniprot id: W5MS81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:rab11fip4
gene id: 7918:rab11fip4
uniprot id: W5N8R8
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

7918:adgrb3
gene id: 7918:adgrb3
uniprot id: W5NKB4
names: Subcellular Location Annotation
messages: Membrane

7918:fabp1
gene id: 7918:fabp1
uniprot id: W5LYZ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

7918:LOC102683847
gene id: 7918:LOC102683847
uniprot id: W5MYN6
uniprot id: W5MYP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

7918:ube2u
gene id: 7918:ube2u
uniprot id: W5MID8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:LOC102694108
gene id: 7918:LOC102694108
uniprot id: W5M6M0
names: Similarity
messages: Belongs to the serpin family.

7918:p3h2
gene id: 7918:p3h2
uniprot id: W5MCS2
names: Similarity
messages: Belongs to the leprecan family.

7918:lyrm5
gene id: 7918:lyrm5
uniprot id: W5NE10
names: Similarity
messages: Belongs to the complex I LYR family.

7918:LOC102689930
gene id: 7918:LOC102689930
uniprot id: W5N3W8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:ddah1
gene id: 7918:ddah1
uniprot id: W5MDQ8
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

7918:derl2
gene id: 7918:derl2
uniprot id: W5M358
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:gpsm2
gene id: 7918:gpsm2
uniprot id: W5MM52
names: Similarity
messages: Belongs to the GPSM family.

7918:prrx2
gene id: 7918:prrx2
uniprot id: A0A075B5H9
uniprot id: W5VVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

7918:LOC102685500
gene id: 7918:LOC102685500
uniprot id: W5LZQ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

7918:grm7
gene id: 7918:grm7
uniprot id: W5N794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

7918:LOC102689698
gene id: 7918:LOC102689698
uniprot id: W5MGW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

7918:LOC102682377
gene id: 7918:LOC102682377
uniprot id: W5M2Y6
names: Similarity
messages: Belongs to the peptidase M17 family.

7918:cnot10
gene id: 7918:cnot10
uniprot id: W5LZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT10 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.
messages: Cytoplasm
messages: Nucleus

7918:LOC102687482
gene id: 7918:LOC102687482
uniprot id: W5MHA0
names: Subcellular Location Annotation
messages: Nucleus

7918:trpm3
gene id: 7918:trpm3
uniprot id: W5MTD7
names: Subcellular Location Annotation
messages: Membrane

7918:znf488
gene id: 7918:znf488
uniprot id: W5M8D9
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102694928
gene id: 7918:LOC102694928
uniprot id: W5LZ61
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:gchfr
gene id: 7918:gchfr
uniprot id: W5N4U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

7918:chrm3
gene id: 7918:chrm3
uniprot id: W5NLG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

7918:gja9
gene id: 7918:gja9
uniprot id: W5NP33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:basp1
gene id: 7918:basp1
uniprot id: W5NNQ2
names: Similarity
messages: Belongs to the BASP1 family.

7918:cux2
gene id: 7918:cux2
uniprot id: W5MKU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

7918:rpl15
gene id: 7918:rpl15
uniprot id: W5MIL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL15 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: Cytoplasm

7918:tp53inp2
gene id: 7918:tp53inp2
uniprot id: W5MAD2
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

7918:spock3
gene id: 7918:spock3
uniprot id: W5M6Y0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:gpr83
gene id: 7918:gpr83
uniprot id: W5ML47
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:osbpl11
gene id: 7918:osbpl11
uniprot id: W5M4M2
names: Similarity
messages: Belongs to the OSBP family.

7918:LOC102695978
gene id: 7918:LOC102695978
uniprot id: W5MS72
names: Similarity
messages: Belongs to the hexokinase family.

7918:LOC102696224
gene id: 7918:LOC102696224
uniprot id: W5MJE7
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

7918:slc1a7
gene id: 7918:slc1a7
uniprot id: W5MGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

7918:smad6
gene id: 7918:smad6
uniprot id: W5N921
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

7918:hoxa13
gene id: 7918:hoxa13
uniprot id: W5N1Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

7918:fkrp
gene id: 7918:fkrp
uniprot id: W5NMH5
names: Similarity
messages: Belongs to the LicD transferase family.

7918:creb5
gene id: 7918:creb5
uniprot id: W5N1Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.
messages: Binds to the cAMP response element and activates transcription.
messages: Nucleus

7918:tfb2m
gene id: 7918:tfb2m
uniprot id: W5NIV4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:popdc2
gene id: 7918:popdc2
uniprot id: W5M212
names: Similarity
messages: Belongs to the popeye family.

7918:LOC102691855
gene id: 7918:LOC102691855
uniprot id: W5NKY0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:gsr
gene id: 7918:gsr
uniprot id: W5N2R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

7918:aldoc
gene id: 7918:aldoc
uniprot id: W5MFX9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

7918:gng7
gene id: 7918:gng7
uniprot id: W5LXE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

7918:amotl2
gene id: 7918:amotl2
uniprot id: W5MD77
names: Similarity
messages: Belongs to the angiomotin family.

7918:abcc2
gene id: 7918:abcc2
uniprot id: W5N534
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

7918:pde4c
gene id: 7918:pde4c
uniprot id: W5M1P0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:amfr
gene id: 7918:amfr
uniprot id: W5MJ61
names: Subcellular Location Annotation
messages: Membrane

7918:nphs2
gene id: 7918:nphs2
uniprot id: W5MRM9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

7918:uba5
gene id: 7918:uba5
uniprot id: W5N0U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
messages: Golgi apparatus

7918:cdc34
gene id: 7918:cdc34
uniprot id: W5MHA7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:tmem57
gene id: 7918:tmem57
uniprot id: W5M414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

7918:lacc1
gene id: 7918:lacc1
uniprot id: W5MEJ7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

7918:uba7
gene id: 7918:uba7
uniprot id: W5MY20
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

7918:LOC107078618
gene id: 7918:LOC107078618
uniprot id: W5MGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

7918:p3h3
gene id: 7918:p3h3
uniprot id: W5MM55
names: Similarity
messages: Belongs to the leprecan family.

7918:mterf1
gene id: 7918:mterf1
uniprot id: W5NP90
names: Similarity
messages: Belongs to the mTERF family.

7918:dcp2
gene id: 7918:dcp2
uniprot id: W5MRH8
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

7918:LOC102691058
gene id: 7918:LOC102691058
uniprot id: W5NFF1
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

7918:specc1l
gene id: 7918:specc1l
uniprot id: W5MJK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

7918:LOC102691210
gene id: 7918:LOC102691210
uniprot id: W5ND05
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

7918:ndufb11
gene id: 7918:ndufb11
uniprot id: W5NAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

7918:ppp4r2
gene id: 7918:ppp4r2
uniprot id: W5MUV0
names: Similarity
messages: Belongs to the PPP4R2 family.

7918:LOC102692206
gene id: 7918:LOC102692206
uniprot id: W5N9H5
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

7918:dock8
gene id: 7918:dock8
uniprot id: W5MSN1
names: Similarity
messages: Belongs to the DOCK family.

7918:LOC102695349
gene id: 7918:LOC102695349
uniprot id: W5N6C7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

7918:coq6
gene id: 7918:coq6
uniprot id: W5MYN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

7918:gpatch11
gene id: 7918:gpatch11
uniprot id: W5NG43
names: Similarity
messages: Belongs to the GPATCH11 family.

7918:atg7
gene id: 7918:atg7
uniprot id: W5N955
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress.
messages: Homodimer.
messages: Preautophagosomal structure

7918:LOC102692643
gene id: 7918:LOC102692643
uniprot id: W5MJ43
names: Subcellular Location Annotation
messages: Nucleus

7918:trappc3
gene id: 7918:trappc3
uniprot id: W5M0H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

7918:mex3c
gene id: 7918:mex3c
uniprot id: W5N5E4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:hdc
gene id: 7918:hdc
uniprot id: W5N5X4
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

7918:pcsk2
gene id: 7918:pcsk2
uniprot id: W5NGE3
names: Similarity
messages: Belongs to the peptidase S8 family.

7918:tmem8c
gene id: 7918:tmem8c
uniprot id: W5M3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

7918:LOC102694151
gene id: 7918:LOC102694151
uniprot id: W5LY03
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

7918:tcea1
gene id: 7918:tcea1
uniprot id: W5MES7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

7918:esrrg
gene id: 7918:esrrg
uniprot id: W5NGM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

7918:shox
gene id: 7918:shox
uniprot id: W5M3K7
names: Subcellular Location Annotation
messages: Nucleus

7918:gmnn
gene id: 7918:gmnn
uniprot id: W5MAW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

7918:dolpp1
gene id: 7918:dolpp1
uniprot id: W5M9L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

7918:copb1
gene id: 7918:copb1
uniprot id: W5M5X7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

7918:slc8a1
gene id: 7918:slc8a1
uniprot id: W5NFH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

7918:zc3h12b
gene id: 7918:zc3h12b
uniprot id: W5NBK0
names: Similarity
messages: Belongs to the ZC3H12 family.

7918:LOC102682156
gene id: 7918:LOC102682156
uniprot id: W5MVA1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:pofut2
gene id: 7918:pofut2
uniprot id: W5MA61
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

7918:slc17a5
gene id: 7918:slc17a5
uniprot id: W5NH12
names: Subcellular Location Annotation
messages: Membrane

7918:mocos
gene id: 7918:mocos
uniprot id: W5MCM0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

7918:atp5f1
gene id: 7918:atp5f1
uniprot id: W5MZN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

7918:tbx4
gene id: 7918:tbx4
uniprot id: W5MCI9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

7918:bcar1
gene id: 7918:bcar1
uniprot id: W5MMY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

7918:ctnnbip1
gene id: 7918:ctnnbip1
uniprot id: W5MIS0
names: Similarity
messages: Belongs to the CTNNBIP1 family.

7918:rad1
gene id: 7918:rad1
uniprot id: W5N1G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

7918:chrna2
gene id: 7918:chrna2
uniprot id: W5NL17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:mfrp
gene id: 7918:mfrp
uniprot id: W5MHJ1
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102697829
gene id: 7918:LOC102697829
uniprot id: W5MXV3
names: Similarity
messages: Belongs to the peptidase C14A family.

7918:tdrd3
gene id: 7918:tdrd3
uniprot id: W5MB28
names: Function
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1.

7918:acss1
gene id: 7918:acss1
uniprot id: W5NJF0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

7918:itpa
gene id: 7918:itpa
uniprot id: W5MWK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

7918:nkrf
gene id: 7918:nkrf
uniprot id: W5NDN4
names: Similarity
messages: Belongs to the CARF family.

7918:insig2
gene id: 7918:insig2
uniprot id: W5M5U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

7918:osbpl1a
gene id: 7918:osbpl1a
uniprot id: W5MHF0
names: Similarity
messages: Belongs to the OSBP family.

7918:fam214b
gene id: 7918:fam214b
uniprot id: W5MAB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

7918:map3k9
gene id: 7918:map3k9
uniprot id: W5N9K2
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

7918:mtmr8
gene id: 7918:mtmr8
uniprot id: W5NBI1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

7918:wnt4
gene id: 7918:wnt4
uniprot id: W5LYR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:exoc6
gene id: 7918:exoc6
uniprot id: W5MJE5
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

7918:gprc5c
gene id: 7918:gprc5c
uniprot id: W5N609
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:fbxo45
gene id: 7918:fbxo45
uniprot id: W5MTZ5
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

7918:adora2b
gene id: 7918:adora2b
uniprot id: W5M746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:tspan1
gene id: 7918:tspan1
uniprot id: W5MEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:dym
gene id: 7918:dym
uniprot id: W5N149
names: Similarity
messages: Belongs to the dymeclin family.

7918:cpvl
gene id: 7918:cpvl
uniprot id: W5M9P0
names: Similarity
messages: Belongs to the peptidase S10 family.

7918:LOC102695056
gene id: 7918:LOC102695056
uniprot id: W5NBF2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

7918:prkci
gene id: 7918:prkci
uniprot id: W5MK54
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

7918:ugt8
gene id: 7918:ugt8
uniprot id: W5M6S2
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

7918:adamts2
gene id: 7918:adamts2
uniprot id: W5MVG7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:ccser1
gene id: 7918:ccser1
uniprot id: W5N5F0
names: Similarity
messages: Belongs to the CCSER family.

7918:LOC107075725
gene id: 7918:LOC107075725
uniprot id: W5MLJ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102686319
gene id: 7918:LOC102686319
uniprot id: W5NLY3
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102693725
gene id: 7918:LOC102693725
uniprot id: W5M2Q3
names: Subcellular Location Annotation
messages: Membrane

7918:tacr3
gene id: 7918:tacr3
uniprot id: W5N2C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:smg9
gene id: 7918:smg9
uniprot id: W5M981
names: Similarity
messages: Belongs to the SMG9 family.

7918:LOC102686983
gene id: 7918:LOC102686983
uniprot id: W5MPD6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

7918:calcrl
gene id: 7918:calcrl
uniprot id: W5MG28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

7918:c1d
gene id: 7918:c1d
uniprot id: W5NGH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

7918:f3
gene id: 7918:f3
uniprot id: W5MNC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

7918:atl1
gene id: 7918:atl1
uniprot id: W5N1V8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

7918:fmnl2
gene id: 7918:fmnl2
uniprot id: W5MEC8
names: Similarity
messages: Belongs to the formin homology family.

7918:abcb1
gene id: 7918:abcb1
uniprot id: W5MWI1
names: Subcellular Location Annotation
messages: Membrane

7918:enoph1
gene id: 7918:enoph1
uniprot id: W5MXN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

7918:romo1
gene id: 7918:romo1
uniprot id: W5MK85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

7918:hhat
gene id: 7918:hhat
uniprot id: W5NEX7
names: Subcellular Location Annotation
messages: Membrane

7918:dimt1
gene id: 7918:dimt1
uniprot id: W5MMA5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

7918:psmb2
gene id: 7918:psmb2
uniprot id: W5LXC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

7918:htr1a
gene id: 7918:htr1a
uniprot id: W5NLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:denr
gene id: 7918:denr
uniprot id: W5ME29
names: Similarity
messages: Belongs to the DENR family.

7918:LOC102691074
gene id: 7918:LOC102691074
uniprot id: W5NB05
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

7918:stambp
gene id: 7918:stambp
uniprot id: W5ND52
names: Similarity
messages: Belongs to the peptidase M67C family.

7918:LOC102698011
gene id: 7918:LOC102698011
uniprot id: W5MSP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:sema6d
gene id: 7918:sema6d
uniprot id: W5N6U0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:arsg
gene id: 7918:arsg
uniprot id: W5N3V6
names: Similarity
messages: Belongs to the sulfatase family.

7918:fez1
gene id: 7918:fez1
uniprot id: W5MCM5
names: Similarity
messages: Belongs to the zygin family.

7918:LOC102687742
gene id: 7918:LOC102687742
uniprot id: W5NC83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:LOC102682208
gene id: 7918:LOC102682208
uniprot id: W5M4X5
names: Similarity
messages: Belongs to the neuritin family.

7918:itga1
gene id: 7918:itga1
uniprot id: W5MIT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

7918:ap1m2
gene id: 7918:ap1m2
uniprot id: W5MM38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

7918:tfrc
gene id: 7918:tfrc
uniprot id: W5MJ70
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

7918:fgfbp1
gene id: 7918:fgfbp1
uniprot id: W5NNS2
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

7918:irx2
gene id: 7918:irx2
uniprot id: W5MQV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

7918:tmem38a
gene id: 7918:tmem38a
uniprot id: W5M070
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

7918:ppil1
gene id: 7918:ppil1
uniprot id: W5N4E9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

7918:pisd
gene id: 7918:pisd
uniprot id: W5LZY6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

7918:pkd2l1
gene id: 7918:pkd2l1
uniprot id: W5MZX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane
messages: cilium membrane

7918:dusp10
gene id: 7918:dusp10
uniprot id: W5NHY7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

7918:ddx21
gene id: 7918:ddx21
uniprot id: W5MRW7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

7918:mex3a
gene id: 7918:mex3a
uniprot id: W5MQW6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:rpl13
gene id: 7918:rpl13
uniprot id: W5M8Z4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

7918:ano7
gene id: 7918:ano7
uniprot id: W5MRH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

7918:arrb1
gene id: 7918:arrb1
uniprot id: W5M3W4
names: Similarity
messages: Belongs to the arrestin family.

7918:itga2
gene id: 7918:itga2
uniprot id: W5MIW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

7918:gfra2
gene id: 7918:gfra2
uniprot id: W5NCJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

7918:ccnc
gene id: 7918:ccnc
uniprot id: W5NKF6
names: Similarity
messages: Belongs to the cyclin family.

7918:mcts1
gene id: 7918:mcts1
uniprot id: W5NDR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

7918:phc2
gene id: 7918:phc2
uniprot id: W5M7N4
names: Subcellular Location Annotation
messages: Nucleus

7918:atp6v0a2
gene id: 7918:atp6v0a2
uniprot id: W5MFM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

7918:snrnp200
gene id: 7918:snrnp200
uniprot id: W5NDJ9
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

7918:itm2b
gene id: 7918:itm2b
uniprot id: W5MWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

7918:LOC102694961
gene id: 7918:LOC102694961
uniprot id: W5MT11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

7918:reep6
gene id: 7918:reep6
uniprot id: W5LWZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

7918:LOC102682579
gene id: 7918:LOC102682579
uniprot id: W5MSS9
names: Similarity
messages: Belongs to the centaurin gamma-like family.

7918:LOC102685941
gene id: 7918:LOC102685941
uniprot id: W5NCH4
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

7918:spire1
gene id: 7918:spire1
uniprot id: W5MUY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

7918:clg12h2orf88
gene id: 7918:clg12h2orf88
uniprot id: W5NMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

7918:sgta
gene id: 7918:sgta
uniprot id: W5LWG4
names: Similarity
messages: Belongs to the SGT family.

7918:jph1
gene id: 7918:jph1
uniprot id: W5M7G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

7918:gcsh
gene id: 7918:gcsh
uniprot id: W5M8V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

7918:ttc19
gene id: 7918:ttc19
uniprot id: W5MW24
names: Similarity
messages: Belongs to the TTC19 family.

7918:gng5
gene id: 7918:gng5
uniprot id: W5MVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

7918:rab18
gene id: 7918:rab18
uniprot id: W5ML35
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

7918:sept12
gene id: 7918:sept12
uniprot id: W5MID6
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

7918:LOC102698397
gene id: 7918:LOC102698397
uniprot id: W5M8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:mtrf1
gene id: 7918:mtrf1
uniprot id: W5MFL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

7918:mustn1
gene id: 7918:mustn1
uniprot id: W5NB12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

7918:meis2
gene id: 7918:meis2
uniprot id: W5N349
uniprot id: W5N356
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

7918:znf711
gene id: 7918:znf711
uniprot id: W5NCH6
names: Subcellular Location Annotation
messages: Nucleus

7918:ube4b
gene id: 7918:ube4b
uniprot id: W5MIE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

7918:LOC102698564
gene id: 7918:LOC102698564
uniprot id: W5MRT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

7918:mon2
gene id: 7918:mon2
uniprot id: W5NK40
names: Similarity
messages: Belongs to the MON2 family.

7918:LOC102693979
gene id: 7918:LOC102693979
uniprot id: W5MN93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

7918:slc35c2
gene id: 7918:slc35c2
uniprot id: W5M4C8
names: Subcellular Location Annotation
messages: Membrane

7918:fam109a
gene id: 7918:fam109a
uniprot id: W5NNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

7918:LOC107077642
gene id: 7918:LOC107077642
uniprot id: W5MWD8
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

7918:ccnyl1
gene id: 7918:ccnyl1
uniprot id: W5M9R1
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

7918:LOC102683953
gene id: 7918:LOC102683953
uniprot id: W5M1G5
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.

7918:mak16
gene id: 7918:mak16
uniprot id: W5NDC0
names: Similarity
messages: Belongs to the MAK16 family.

7918:LOC102697743
gene id: 7918:LOC102697743
uniprot id: W5N8L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:b3gat2
gene id: 7918:b3gat2
uniprot id: W5NKI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:tube1
gene id: 7918:tube1
uniprot id: W5NK34
names: Similarity
messages: Belongs to the tubulin family.

7918:LOC102694802
gene id: 7918:LOC102694802
uniprot id: W5MRD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

7918:slc22a31
gene id: 7918:slc22a31
uniprot id: W5MAU1
names: Subcellular Location Annotation
messages: Membrane

7918:med8
gene id: 7918:med8
uniprot id: W5MA52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

7918:galntl6
gene id: 7918:galntl6
uniprot id: W5N7V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:grpel1
gene id: 7918:grpel1
uniprot id: W5MVQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

7918:pqlc1
gene id: 7918:pqlc1
uniprot id: W5MPF3
names: Subcellular Location Annotation
messages: Membrane

7918:cops7a
gene id: 7918:cops7a
uniprot id: W5MMG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

7918:LOC102683613
gene id: 7918:LOC102683613
uniprot id: W5N136
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

7918:mterf2
gene id: 7918:mterf2
uniprot id: W5NMZ1
names: Similarity
messages: Belongs to the mTERF family.

7918:ppp2ca
gene id: 7918:ppp2ca
uniprot id: W5MVW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

7918:hhatl
gene id: 7918:hhatl
uniprot id: W5MTW1
names: Subcellular Location Annotation
messages: Membrane

7918:txlna
gene id: 7918:txlna
uniprot id: W5M308
names: Similarity
messages: Belongs to the taxilin family.

7918:LOC102695873
gene id: 7918:LOC102695873
uniprot id: W5MYD3
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:slc24a4
gene id: 7918:slc24a4
uniprot id: W5N9S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

7918:LOC102687631
gene id: 7918:LOC102687631
uniprot id: W5MBM0
names: Similarity
messages: Belongs to the peptidase C1 family.

7918:scfd2
gene id: 7918:scfd2
uniprot id: W5N9U0
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

7918:LOC102698052
gene id: 7918:LOC102698052
uniprot id: W5MKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

7918:p2ry8
gene id: 7918:p2ry8
uniprot id: W5NML6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:notch1
gene id: 7918:notch1
uniprot id: W5M6R2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

7918:ppm1l
gene id: 7918:ppm1l
uniprot id: W5M784
names: Similarity
messages: Belongs to the PP2C family.

7918:ptk7
gene id: 7918:ptk7
uniprot id: W5NG04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:nptx1
gene id: 7918:nptx1
uniprot id: W5N7E0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:fut8
gene id: 7918:fut8
uniprot id: A0A0A1TKW1
uniprot id: W5N9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

7918:LOC102698126
gene id: 7918:LOC102698126
uniprot id: W5N9U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:eif4e1b
gene id: 7918:eif4e1b
uniprot id: W5N1P4
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

7918:lsm4
gene id: 7918:lsm4
uniprot id: W5M1T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

7918:saraf
gene id: 7918:saraf
uniprot id: W5M444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:LOC102690600
gene id: 7918:LOC102690600
uniprot id: W5N3N5
names: Subcellular Location Annotation
messages: Cytoplasm

7918:dock5
gene id: 7918:dock5
uniprot id: W5NF97
names: Similarity
messages: Belongs to the DOCK family.

7918:LOC102687462
gene id: 7918:LOC102687462
uniprot id: W5LZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

7918:gpr61
gene id: 7918:gpr61
uniprot id: W5NN37
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:rrp36
gene id: 7918:rrp36
uniprot id: W5NFX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

7918:coro6
gene id: 7918:coro6
uniprot id: W5MHW1
names: Similarity
messages: Belongs to the WD repeat coronin family.

7918:LOC102684739
gene id: 7918:LOC102684739
uniprot id: W5MT62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

7918:nhp2
gene id: 7918:nhp2
uniprot id: W5MTQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

7918:kcna1
gene id: 7918:kcna1
uniprot id: W5NN03
names: Subcellular Location Annotation
messages: Membrane

7918:daw1
gene id: 7918:daw1
uniprot id: W5MNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

7918:arhgef3
gene id: 7918:arhgef3
uniprot id: W5N723
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

7918:gbf1
gene id: 7918:gbf1
uniprot id: W5MTH0
names: Subcellular Location Annotation
messages: Golgi apparatus

7918:slc30a3
gene id: 7918:slc30a3
uniprot id: W5NFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

7918:cluh
gene id: 7918:cluh
uniprot id: W5MAD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

7918:pcolce2
gene id: 7918:pcolce2
uniprot id: W5MMF7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:sox1
gene id: 7918:sox1
uniprot id: W5NMP4
names: Subcellular Location Annotation
messages: Nucleus

7918:slco5a1
gene id: 7918:slco5a1
uniprot id: W5M9B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

7918:dscc1
gene id: 7918:dscc1
uniprot id: W5MS32
names: Similarity
messages: Belongs to the DCC1 family.

7918:snx9
gene id: 7918:snx9
uniprot id: W5NJ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

7918:iqsec1
gene id: 7918:iqsec1
uniprot id: W5N9I3
names: Similarity
messages: Belongs to the BRAG family.

7918:mgmt
gene id: 7918:mgmt
uniprot id: W5MLJ7
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

7918:LOC102683145
gene id: 7918:LOC102683145
uniprot id: W5MES6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

7918:clg4h20orf27
gene id: 7918:clg4h20orf27
uniprot id: W5M0C2
names: Similarity
messages: Belongs to the ADISSP family.

7918:psma3
gene id: 7918:psma3
uniprot id: W5MSR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

7918:KEF94 p11
gene id: 7918:KEF94_p11
uniprot id: Q8HQN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

7918:sf3b5
gene id: 7918:sf3b5
uniprot id: W5NLE8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

7918:LOC102686519
gene id: 7918:LOC102686519
uniprot id: W5LZY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

7918:neurod2
gene id: 7918:neurod2
uniprot id: W5NLW4
names: Subcellular Location Annotation
messages: Nucleus

7918:pigu
gene id: 7918:pigu
uniprot id: W5MKF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:uggt1
gene id: 7918:uggt1
uniprot id: W5MIJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

7918:hoxd9
gene id: 7918:hoxd9
uniprot id: W5MJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

7918:plpp1
gene id: 7918:plpp1
uniprot id: W5MVS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

7918:slc47a1
gene id: 7918:slc47a1
uniprot id: W5MGE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

7918:pou2f3
gene id: 7918:pou2f3
uniprot id: W5M245
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

7918:LOC102693230
gene id: 7918:LOC102693230
uniprot id: W5N294
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

7918:LOC102692895
gene id: 7918:LOC102692895
uniprot id: W5MBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

7918:rpl21
gene id: 7918:rpl21
uniprot id: W5M9C6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

7918:egflam
gene id: 7918:egflam
uniprot id: W5N4K8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:dync2h1
gene id: 7918:dync2h1
uniprot id: W5MJI1
names: Similarity
messages: Belongs to the dynein heavy chain family.

7918:LOC102693503
gene id: 7918:LOC102693503
uniprot id: W5NJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

7918:strip1
gene id: 7918:strip1
uniprot id: W5N139
names: Similarity
messages: Belongs to the STRIP family.

7918:pde8b
gene id: 7918:pde8b
uniprot id: W5MET4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:LOC102697845
gene id: 7918:LOC102697845
uniprot id: W5M384
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

7918:dapk2
gene id: 7918:dapk2
uniprot id: W5NCC4
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:rab32
gene id: 7918:rab32
uniprot id: W5NGY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

7918:ptprd
gene id: 7918:ptprd
uniprot id: W5N6X6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

7918:clg9h5orf22
gene id: 7918:clg9h5orf22
uniprot id: W5N5C4
names: Similarity
messages: Belongs to the UPF0489 family.

7918:mrps25
gene id: 7918:mrps25
uniprot id: W5MZB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

7918:gabrg3
gene id: 7918:gabrg3
uniprot id: W5MNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:alx4
gene id: 7918:alx4
uniprot id: W5M4M0
names: Subcellular Location Annotation
messages: Nucleus

7918:hcn4
gene id: 7918:hcn4
uniprot id: W5NBA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

7918:ddr2
gene id: 7918:ddr2
uniprot id: W5MJU0
names: Subcellular Location Annotation
messages: Membrane

7918:fam160b1
gene id: 7918:fam160b1
uniprot id: W5N5T4
names: Similarity
messages: Belongs to the FHIP family.

7918:hgd
gene id: 7918:hgd
uniprot id: W5M1I1
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

7918:LOC102695719
gene id: 7918:LOC102695719
uniprot id: W5N335
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

7918:LOC102696916
gene id: 7918:LOC102696916
uniprot id: W5N2K7
names: Similarity
messages: Belongs to the cytochrome b5 family.

7918:LOC107079496
gene id: 7918:LOC107079496
uniprot id: W5MXK8
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

7918:LOC102691579
gene id: 7918:LOC102691579
uniprot id: W5MDR4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

7918:wdr4
gene id: 7918:wdr4
uniprot id: W5M8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat TRM82 family.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

7918:ilvbl
gene id: 7918:ilvbl
uniprot id: W5M4Y1
names: Similarity
messages: Belongs to the TPP enzyme family.

7918:camk2b
gene id: 7918:camk2b
uniprot id: W5NDX0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

7918:LOC102684901
gene id: 7918:LOC102684901
uniprot id: W5NG90
names: Similarity
messages: Belongs to the IL-17 family.

7918:LOC102692823
gene id: 7918:LOC102692823
uniprot id: W5NCU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

7918:lamb3
gene id: 7918:lamb3
uniprot id: W5MZY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:u2af2
gene id: 7918:u2af2
uniprot id: W5MY39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

7918:ccne1
gene id: 7918:ccne1
uniprot id: W5MEP2
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

7918:smg8
gene id: 7918:smg8
uniprot id: W5LZ40
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

7918:ybey
gene id: 7918:ybey
uniprot id: W5MR38
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

7918:cenpq
gene id: 7918:cenpq
uniprot id: W5MYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

7918:klc4
gene id: 7918:klc4
uniprot id: W5NFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

7918:mrpl51
gene id: 7918:mrpl51
uniprot id: W5MJP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.
messages: Mitochondrion

7918:ssr4
gene id: 7918:ssr4
uniprot id: W5NA95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

7918:LOC102686415
gene id: 7918:LOC102686415
uniprot id: W5MQL3
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:cck
gene id: 7918:cck
uniprot id: W5LZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

7918:mrpl4
gene id: 7918:mrpl4
uniprot id: W5NIT7
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

7918:naa10
gene id: 7918:naa10
uniprot id: W5NCD4
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

7918:junb
gene id: 7918:junb
uniprot id: W5NP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

7918:adgra2
gene id: 7918:adgra2
uniprot id: W5NCP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

7918:unkl
gene id: 7918:unkl
uniprot id: W5M7H9
uniprot id: W5M7J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

7918:LOC102689735
gene id: 7918:LOC102689735
uniprot id: W5MP19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

7918:gosr2
gene id: 7918:gosr2
uniprot id: W5N388
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

7918:mchr2
gene id: 7918:mchr2
uniprot id: W5NKF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:mpp2
gene id: 7918:mpp2
uniprot id: W5N6A4
names: Similarity
messages: Belongs to the MAGUK family.

7918:LOC107075561
gene id: 7918:LOC107075561
uniprot id: W5ME97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

7918:trdmt1
gene id: 7918:trdmt1
uniprot id: W5MX29
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

7918:alg9
gene id: 7918:alg9
uniprot id: W5LZL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:sh3gl2
gene id: 7918:sh3gl2
uniprot id: W5N201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

7918:LOC102697379
gene id: 7918:LOC102697379
uniprot id: W5MTM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ergic3
gene id: 7918:ergic3
uniprot id: W5MK65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

7918:dhtkd1
gene id: 7918:dhtkd1
uniprot id: W5NFC7
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

7918:rogdi
gene id: 7918:rogdi
uniprot id: W5LYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Presynapse
messages: Vesicle
messages: synaptic vesicle

7918:chga
gene id: 7918:chga
uniprot id: W5N679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

7918:dlx2
gene id: 7918:dlx2
uniprot id: W5MLF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

7918:arsi
gene id: 7918:arsi
uniprot id: W5MZ90
names: Similarity
messages: Belongs to the sulfatase family.

7918:neo1
gene id: 7918:neo1
uniprot id: W5NCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

7918:metap1
gene id: 7918:metap1
uniprot id: W5N309
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

7918:LOC102697368
gene id: 7918:LOC102697368
uniprot id: W5MTN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

7918:rfx2
gene id: 7918:rfx2
uniprot id: W5LY52
names: Subcellular Location Annotation
messages: Nucleus

7918:gpr137b
gene id: 7918:gpr137b
uniprot id: W5NFR8
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

7918:ptpn21
gene id: 7918:ptpn21
uniprot id: W5MPE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

7918:fam189a2
gene id: 7918:fam189a2
uniprot id: W5MT24
names: Similarity
messages: Belongs to the ENTREP family.

7918:phtf2
gene id: 7918:phtf2
uniprot id: W5NGG2
names: Subcellular Location Annotation
messages: Membrane

7918:kin
gene id: 7918:kin
uniprot id: W5NF93
names: Similarity
messages: Belongs to the KIN17 family.

7918:pard3b
gene id: 7918:pard3b
uniprot id: W5MYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

7918:LOC102682629
gene id: 7918:LOC102682629
uniprot id: W5N0D0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

7918:LOC102689036
gene id: 7918:LOC102689036
uniprot id: W5NKB6
names: Similarity
messages: Belongs to the avidin/streptavidin family.

7918:nasp
gene id: 7918:nasp
uniprot id: W5MFQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

7918:gmfg
gene id: 7918:gmfg
uniprot id: W5NBG2
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

7918:chst2
gene id: 7918:chst2
uniprot id: W5NLK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

7918:xrcc4
gene id: 7918:xrcc4
uniprot id: W5M1T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

7918:tec
gene id: 7918:tec
uniprot id: W5N257
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:tmem39a
gene id: 7918:tmem39a
uniprot id: W5MTR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

7918:pi4ka
gene id: 7918:pi4ka
uniprot id: W5M2N3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

7918:LOC102697049
gene id: 7918:LOC102697049
uniprot id: W5M7D5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

7918:nrn1
gene id: 7918:nrn1
uniprot id: W5N148
names: Similarity
messages: Belongs to the neuritin family.

7918:galnt14
gene id: 7918:galnt14
uniprot id: W5NJE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:mcm6
gene id: 7918:mcm6
uniprot id: W5LXW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

7918:gnb1
gene id: 7918:gnb1
uniprot id: W5MGC5
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

7918:dgcr2
gene id: 7918:dgcr2
uniprot id: W5MC37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:adora2a
gene id: 7918:adora2a
uniprot id: W5MJI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

7918:irf7
gene id: 7918:irf7
uniprot id: W5LWA7
names: Subcellular Location Annotation
messages: Nucleus

7918:zdhhc21
gene id: 7918:zdhhc21
uniprot id: W5MZX6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

7918:nudt21
gene id: 7918:nudt21
uniprot id: W5MMW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus

7918:LOC102698940
gene id: 7918:LOC102698940
uniprot id: W5M4N9
names: Similarity
messages: Belongs to the centrin family.

7918:prok2
gene id: 7918:prok2
uniprot id: W5MV09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

7918:cabin1
gene id: 7918:cabin1
uniprot id: W5MHS8
names: Subcellular Location Annotation
messages: Nucleus

7918:ndufa5
gene id: 7918:ndufa5
uniprot id: W5NFY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

7918:rgmb
gene id: 7918:rgmb
uniprot id: W5MH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

7918:eme1
gene id: 7918:eme1
uniprot id: W5MZ11
names: Similarity
messages: Belongs to the EME1/MMS4 family.

7918:galnt7
gene id: 7918:galnt7
uniprot id: W5N7X2
uniprot id: W5N7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:spsb1
gene id: 7918:spsb1
uniprot id: W5MJB0
names: Similarity
messages: Belongs to the SPSB family.

7918:dnaja4
gene id: 7918:dnaja4
uniprot id: W5NC87
names: Subcellular Location Annotation
messages: Membrane

7918:bcap31
gene id: 7918:bcap31
uniprot id: W5NBE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

7918:cat
gene id: 7918:cat
uniprot id: W5LYH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

7918:bmpr2
gene id: 7918:bmpr2
uniprot id: W5MVP1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

7918:rag2
gene id: 7918:rag2
uniprot id: W5NLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

7918:lcmt1
gene id: 7918:lcmt1
uniprot id: W5MDM9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

7918:LOC102685379
gene id: 7918:LOC102685379
uniprot id: W5NBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

7918:cldn12
gene id: 7918:cldn12
uniprot id: W5NP88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

7918:fam214a
gene id: 7918:fam214a
uniprot id: W5N7C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

7918:rap2a
gene id: 7918:rap2a
uniprot id: W5M7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

7918:cass4
gene id: 7918:cass4
uniprot id: W5M6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

7918:vrk2
gene id: 7918:vrk2
uniprot id: W5NGX7
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:mns1
gene id: 7918:mns1
uniprot id: W5N7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

7918:nr4a3
gene id: 7918:nr4a3
uniprot id: W5MDI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:vgll3
gene id: 7918:vgll3
uniprot id: W5MX24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

7918:rps4x
gene id: 7918:rps4x
uniprot id: W5NAX0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

7918:LOC102689437
gene id: 7918:LOC102689437
uniprot id: W5MF71
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:tpst1
gene id: 7918:tpst1
uniprot id: W5MDA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

7918:igfbp2
gene id: 7918:igfbp2
uniprot id: W5MS99
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:lamp3
gene id: 7918:lamp3
uniprot id: W5LXP0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

7918:svop
gene id: 7918:svop
uniprot id: W5MAN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

7918:ppip5k1
gene id: 7918:ppip5k1
uniprot id: W5NA49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

7918:LOC102698162
gene id: 7918:LOC102698162
uniprot id: W5NEW0
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:traf1
gene id: 7918:traf1
uniprot id: W5MH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

7918:hsd11b2
gene id: 7918:hsd11b2
uniprot id: W5MNG8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:adam8
gene id: 7918:adam8
uniprot id: W5MA26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:kdm1a
gene id: 7918:kdm1a
uniprot id: W5MAF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family.
messages: Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity.
messages: Nucleus
messages: The SWIRM domain may act as an anchor site for a histone tail.

7918:hmgn5
gene id: 7918:hmgn5
uniprot id: W5NCX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

7918:dcbld1
gene id: 7918:dcbld1
uniprot id: W5NKM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:pfn3
gene id: 7918:pfn3
uniprot id: W5NP47
names: Similarity
messages: Belongs to the profilin family.

7918:LOC102692225
gene id: 7918:LOC102692225
uniprot id: W5MEG8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102695321
gene id: 7918:LOC102695321
uniprot id: W5MF68
names: Function
names: Similarity
messages: Belongs to the CMP-Neu5Ac hydroxylase family.
messages: Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.

7918:LOC102683151
gene id: 7918:LOC102683151
uniprot id: W5MF12
names: Similarity
messages: Belongs to the aldo/keto reductase family.

7918:gaa
gene id: 7918:gaa
uniprot id: W5N8Z9
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:tmem8a
gene id: 7918:tmem8a
uniprot id: W5MH54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

7918:hmgcs1
gene id: 7918:hmgcs1
uniprot id: W5MYI8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

7918:llph
gene id: 7918:llph
uniprot id: W5NED1
names: Similarity
messages: Belongs to the learning-associated protein family.

7918:cdca2
gene id: 7918:cdca2
uniprot id: W5NEZ6
names: Subcellular Location Annotation
messages: Nucleus

7918:stc1
gene id: 7918:stc1
uniprot id: W5NCY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

7918:h3f3b
gene id: 7918:h3f3b
uniprot id: W5NA02
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

7918:lhfpl2
gene id: 7918:lhfpl2
uniprot id: W5MF70
names: Subcellular Location Annotation
messages: Membrane

7918:vipr2
gene id: 7918:vipr2
uniprot id: W5N3J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

7918:entpd3
gene id: 7918:entpd3
uniprot id: W5LYE1
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

7918:tmtc2
gene id: 7918:tmtc2
uniprot id: W5NHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

7918:adgrv1
gene id: 7918:adgrv1
uniprot id: W5M0X7
uniprot id: W5M0Z3
names: Subcellular Location Annotation
messages: Membrane

7918:ndufb8
gene id: 7918:ndufb8
uniprot id: W5MDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

7918:pappa2
gene id: 7918:pappa2
uniprot id: W5M2R1
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ube3a
gene id: 7918:ube3a
uniprot id: W5MP80
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

7918:znf830
gene id: 7918:znf830
uniprot id: W5MCG0
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus speckle

7918:wnt16
gene id: 7918:wnt16
uniprot id: W5NFP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:noc4l
gene id: 7918:noc4l
uniprot id: W5MG30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Nucleus membrane

7918:gpatch1
gene id: 7918:gpatch1
uniprot id: W5M143
names: Similarity
messages: Belongs to the GPATCH1 family.

7918:tac1
gene id: 7918:tac1
uniprot id: W5MYV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

7918:eftud2
gene id: 7918:eftud2
uniprot id: W5N0D6
names: Subcellular Location Annotation
messages: Nucleus

7918:atp10a
gene id: 7918:atp10a
uniprot id: W5MP55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

7918:casp6
gene id: 7918:casp6
uniprot id: W5N383
names: Similarity
messages: Belongs to the peptidase C14A family.

7918:mfsd9
gene id: 7918:mfsd9
uniprot id: W5MQ91
names: Subcellular Location Annotation
messages: Membrane

7918:atg3
gene id: 7918:atg3
uniprot id: W5M0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

7918:capn3
gene id: 7918:capn3
uniprot id: W5N7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

7918:tmprss2
gene id: 7918:tmprss2
uniprot id: W5LZM8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:eaf2
gene id: 7918:eaf2
uniprot id: W5M2M4
names: Similarity
messages: Belongs to the EAF family.

7918:LOC102696922
gene id: 7918:LOC102696922
uniprot id: W5MIB7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:tshz2
gene id: 7918:tshz2
uniprot id: W5M3C1
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

7918:golm1
gene id: 7918:golm1
uniprot id: W5M371
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

7918:rorb
gene id: 7918:rorb
uniprot id: W5MU03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:dhcr7
gene id: 7918:dhcr7
uniprot id: W5MCC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

7918:unc5a
gene id: 7918:unc5a
uniprot id: W5N214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

7918:aldh18a1
gene id: 7918:aldh18a1
uniprot id: W5N2X6
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

7918:copg2
gene id: 7918:copg2
uniprot id: W5NF14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

7918:tubgcp3
gene id: 7918:tubgcp3
uniprot id: W5MS07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

7918:lect1
gene id: 7918:lect1
uniprot id: W5MDE1
names: Similarity
messages: Belongs to the chondromodulin-1 family.

7918:agk
gene id: 7918:agk
uniprot id: W5NIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

7918:cacybp
gene id: 7918:cacybp
uniprot id: W5M3A3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

7918:rpn2
gene id: 7918:rpn2
uniprot id: W5LZY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

7918:gna12
gene id: 7918:gna12
uniprot id: W5M9R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

7918:urod
gene id: 7918:urod
uniprot id: W5M569
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

7918:mfsd5
gene id: 7918:mfsd5
uniprot id: W5NNU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

7918:nav2
gene id: 7918:nav2
uniprot id: W5MBS6
names: Similarity
messages: Belongs to the Nav/unc-53 family.

7918:wnt10b
gene id: 7918:wnt10b
uniprot id: W5MM62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:armc9
gene id: 7918:armc9
uniprot id: W5MBU9
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cilium basal body

7918:pllp
gene id: 7918:pllp
uniprot id: W5MLT2
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102687962
gene id: 7918:LOC102687962
uniprot id: W5MV67
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:cachd1
gene id: 7918:cachd1
uniprot id: W5MIF6
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

7918:cdx1
gene id: 7918:cdx1
uniprot id: W5MZ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

7918:irf4
gene id: 7918:irf4
uniprot id: W5N5W4
names: Subcellular Location Annotation
messages: Nucleus

7918:ubap2l
gene id: 7918:ubap2l
uniprot id: W5MLG5
names: Subcellular Location Annotation
messages: Cytoplasm

7918:vat1
gene id: 7918:vat1
uniprot id: W5N071
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

7918:mat1a
gene id: 7918:mat1a
uniprot id: W5N4C3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

7918:nosip
gene id: 7918:nosip
uniprot id: W5NKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.
messages: Nucleus

7918:abcc10
gene id: 7918:abcc10
uniprot id: W5NJ59
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102695885
gene id: 7918:LOC102695885
uniprot id: W5MHK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:dsel
gene id: 7918:dsel
uniprot id: W5NNQ1
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

7918:rpl30
gene id: 7918:rpl30
uniprot id: W5MUG1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

7918:pim2
gene id: 7918:pim2
uniprot id: W5NBD3
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

7918:miox
gene id: 7918:miox
uniprot id: W5NJI0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

7918:ywhag
gene id: 7918:ywhag
uniprot id: W5M4X0
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

7918:gpam
gene id: 7918:gpam
uniprot id: W5N3B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

7918:nob1
gene id: 7918:nob1
uniprot id: W5LZQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

7918:tmed2
gene id: 7918:tmed2
uniprot id: W5MF34
uniprot id: W5MF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

7918:pank4
gene id: 7918:pank4
uniprot id: W5MBK5
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

7918:ogt
gene id: 7918:ogt
uniprot id: W5NCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

7918:bmx
gene id: 7918:bmx
uniprot id: W5MLW3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:cltc
gene id: 7918:cltc
uniprot id: W5M8E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

7918:dnm1
gene id: 7918:dnm1
uniprot id: W5MC01
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

7918:ciao1
gene id: 7918:ciao1
uniprot id: W5NDK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

7918:LOC102694852
gene id: 7918:LOC102694852
uniprot id: W5NN79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

7918:itih2
gene id: 7918:itih2
uniprot id: W5NF90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

7918:ndufc1
gene id: 7918:ndufc1
uniprot id: W5MX32
names: Similarity
names: Subunit
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.

7918:nr1d2
gene id: 7918:nr1d2
uniprot id: W5MIN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:ppp1r9a
gene id: 7918:ppp1r9a
uniprot id: W5MYD7
names: Subcellular Location Annotation
messages: cytoskeleton

7918:hopx
gene id: 7918:hopx
uniprot id: W5MTE7
names: Subcellular Location Annotation
messages: Nucleus

7918:prps2
gene id: 7918:prps2
uniprot id: W5MUX5
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

7918:acsl6
gene id: 7918:acsl6
uniprot id: W5MW90
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

7918:nme7
gene id: 7918:nme7
uniprot id: W5MPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: cilium axoneme

7918:capza1
gene id: 7918:capza1
uniprot id: W5MW64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

7918:sar1b
gene id: 7918:sar1b
uniprot id: W5MVS9
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

7918:syk
gene id: 7918:syk
uniprot id: W5MNI7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

7918:dis3
gene id: 7918:dis3
uniprot id: W5MZV9
names: Similarity
messages: Belongs to the RNR ribonuclease family.

7918:maf1
gene id: 7918:maf1
uniprot id: W5MQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

7918:rps6kb1
gene id: 7918:rps6kb1
uniprot id: W5M868
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

7918:arl2
gene id: 7918:arl2
uniprot id: W5M2C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

7918:LOC102682163
gene id: 7918:LOC102682163
uniprot id: W5MZ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:luc7l3
gene id: 7918:luc7l3
uniprot id: W5MYI0
names: Similarity
messages: Belongs to the Luc7 family.

7918:fam167a
gene id: 7918:fam167a
uniprot id: W5NFR9
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

7918:LOC102683559
gene id: 7918:LOC102683559
uniprot id: W5NLN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:sncg
gene id: 7918:sncg
uniprot id: W5N3W3
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

7918:fam234a
gene id: 7918:fam234a
uniprot id: W5MMH2
names: Similarity
messages: Belongs to the FAM234 family.

7918:pomgnt1
gene id: 7918:pomgnt1
uniprot id: W5MEV3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

7918:LOC102694187
gene id: 7918:LOC102694187
uniprot id: W5NMV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

7918:ccdc124
gene id: 7918:ccdc124
uniprot id: W5M4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC124 family.
messages: Midbody

7918:LOC102689592
gene id: 7918:LOC102689592
uniprot id: W5MWW8
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:KEF94 p03
gene id: 7918:KEF94_p03
uniprot id: Q8HQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

7918:lgr4
gene id: 7918:lgr4
uniprot id: W5MH89
names: Subcellular Location Annotation
messages: Membrane

7918:mpdz
gene id: 7918:mpdz
uniprot id: W5N6R5
names: Subcellular Location Annotation
messages: tight junction

7918:rps19bp1
gene id: 7918:rps19bp1
uniprot id: W5MZ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

7918:ccdc58
gene id: 7918:ccdc58
uniprot id: W5M614
names: Similarity
messages: Belongs to the MIX23 family.

7918:tmem151b
gene id: 7918:tmem151b
uniprot id: W5NHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

7918:myo16
gene id: 7918:myo16
uniprot id: W5MR74
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

7918:cxcr4
gene id: 7918:cxcr4
uniprot id: W5LY38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

7918:nemp2
gene id: 7918:nemp2
uniprot id: W5MUT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

7918:ttll6
gene id: 7918:ttll6
uniprot id: W5N7J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neugrin family.
messages: Forms a regulatory protein-RNA complex, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA. Interacts with 16S mt-rRNA; this interaction is direct.
messages: Mitochondrion membrane
messages: Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.

7918:chek1
gene id: 7918:chek1
uniprot id: W5LY73
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

7918:ndrg1
gene id: 7918:ndrg1
uniprot id: W5MKJ1
uniprot id: W5MKK6
names: Similarity
messages: Belongs to the NDRG family.

7918:hadh
gene id: 7918:hadh
uniprot id: W5N3A9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

7918:LOC102695806
gene id: 7918:LOC102695806
uniprot id: W5N895
names: Similarity
messages: Belongs to the beta-catenin family.

7918:ak3
gene id: 7918:ak3
uniprot id: W5MZK4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

7918:sppl2b
gene id: 7918:sppl2b
uniprot id: W5M9X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

7918:gapdhs
gene id: 7918:gapdhs
uniprot id: W5M727
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

7918:LOC102684856
gene id: 7918:LOC102684856
uniprot id: W5MV41
names: Subcellular Location Annotation
messages: Membrane

7918:cops4
gene id: 7918:cops4
uniprot id: W5MXF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

7918:stac2
gene id: 7918:stac2
uniprot id: W5N526
names: Subcellular Location Annotation
messages: sarcolemma

7918:prdm5
gene id: 7918:prdm5
uniprot id: W5MU99
names: Subcellular Location Annotation
messages: Nucleus

7918:ppm1b
gene id: 7918:ppm1b
uniprot id: W5NHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

7918:trmt61a
gene id: 7918:trmt61a
uniprot id: W5MUR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

7918:gria4
gene id: 7918:gria4
uniprot id: W5MJA4
uniprot id: W5MJC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

7918:LOC102695483
gene id: 7918:LOC102695483
uniprot id: W5MAV4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

7918:tfpi
gene id: 7918:tfpi
uniprot id: W5MG64
names: Subcellular Location Annotation
messages: Secreted

7918:LOC102698566
gene id: 7918:LOC102698566
uniprot id: W5MN89
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102688336
gene id: 7918:LOC102688336
uniprot id: W5M7H7
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:flt3
gene id: 7918:flt3
uniprot id: W5M9U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:ict1
gene id: 7918:ict1
uniprot id: W5N0E2
names: Subcellular Location Annotation
messages: Mitochondrion

7918:ppp3cc
gene id: 7918:ppp3cc
uniprot id: W5NEB9
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

7918:tp53bp1
gene id: 7918:tp53bp1
uniprot id: W5NA27
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102690567
gene id: 7918:LOC102690567
uniprot id: W5NMC8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:pim3
gene id: 7918:pim3
uniprot id: W5NGK0
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

7918:adcy7
gene id: 7918:adcy7
uniprot id: W5MKQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

7918:kpnb1
gene id: 7918:kpnb1
uniprot id: W5N8K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

7918:usp3
gene id: 7918:usp3
uniprot id: W5NCF8
names: Similarity
messages: Belongs to the peptidase C19 family.

7918:efnb2
gene id: 7918:efnb2
uniprot id: W5MZ01
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:LOC102688627
gene id: 7918:LOC102688627
uniprot id: W5M116
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

7918:actr3
gene id: 7918:actr3
uniprot id: W5M547
names: Similarity
messages: Belongs to the actin family.

7918:dohh
gene id: 7918:dohh
uniprot id: W5LZF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

7918:rps6ka1
gene id: 7918:rps6ka1
uniprot id: W5MDY7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

7918:polr3h
gene id: 7918:polr3h
uniprot id: W5N0X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

7918:LOC102686641
gene id: 7918:LOC102686641
uniprot id: W5NJI1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

7918:LOC107078555
gene id: 7918:LOC107078555
uniprot id: W5NP12
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:tmsb4x
gene id: 7918:tmsb4x
uniprot id: W5MV16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

7918:tmem186
gene id: 7918:tmem186
uniprot id: W5MHT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

7918:pcsk5
gene id: 7918:pcsk5
uniprot id: W5MUD3
names: Similarity
messages: Belongs to the peptidase S8 family.

7918:slco4a1
gene id: 7918:slco4a1
uniprot id: W5MFK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:cep290
gene id: 7918:cep290
uniprot id: W5NHU3
names: Subcellular Location Annotation
messages: cilium basal body

7918:thoc5
gene id: 7918:thoc5
uniprot id: W5MPB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

7918:LOC102691037
gene id: 7918:LOC102691037
uniprot id: W5MRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

7918:lin28a
gene id: 7918:lin28a
uniprot id: W5M6F0
names: Similarity
messages: Belongs to the lin-28 family.

7918:agtpbp1
gene id: 7918:agtpbp1
uniprot id: W5M2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

7918:ptcd2
gene id: 7918:ptcd2
uniprot id: W5MZ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

7918:sema5b
gene id: 7918:sema5b
uniprot id: W5M396
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:KEF94 p04
gene id: 7918:KEF94_p04
uniprot id: Q8HQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

7918:gadd45b
gene id: 7918:gadd45b
uniprot id: W5LXI1
names: Similarity
messages: Belongs to the GADD45 family.

7918:LOC102692212
gene id: 7918:LOC102692212
uniprot id: W5NJL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:LOC102686767
gene id: 7918:LOC102686767
uniprot id: W5MNJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

7918:papolg
gene id: 7918:papolg
uniprot id: W5NGX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

7918:stmn3
gene id: 7918:stmn3
uniprot id: W5M0S2
names: Similarity
messages: Belongs to the stathmin family.

7918:foxf1
gene id: 7918:foxf1
uniprot id: W5LYG4
names: Subcellular Location Annotation
messages: Nucleus

7918:mab21l2
gene id: 7918:mab21l2
uniprot id: W5NNB6
names: Similarity
messages: Belongs to the mab-21 family.

7918:kcnn2
gene id: 7918:kcnn2
uniprot id: W5MRE5
names: Subcellular Location Annotation
messages: Membrane

7918:slc28a1
gene id: 7918:slc28a1
uniprot id: W5NBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

7918:LOC102698019
gene id: 7918:LOC102698019
uniprot id: W5N333
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

7918:slc24a3
gene id: 7918:slc24a3
uniprot id: W5NH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

7918:atp2b1
gene id: 7918:atp2b1
uniprot id: W5NHX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:sirt5
gene id: 7918:sirt5
uniprot id: W5N683
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:gfod1
gene id: 7918:gfod1
uniprot id: W5MX86
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

7918:rplp2
gene id: 7918:rplp2
uniprot id: W5MX37
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

7918:slc26a5
gene id: 7918:slc26a5
uniprot id: W5NGB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

7918:mrpl28
gene id: 7918:mrpl28
uniprot id: W5NCC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

7918:eif4h
gene id: 7918:eif4h
uniprot id: W5LXX0
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

7918:gdnf
gene id: 7918:gdnf
uniprot id: W5N4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

7918:fam162b
gene id: 7918:fam162b
uniprot id: W5NKK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

7918:srp14
gene id: 7918:srp14
uniprot id: W5N535
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

7918:metap1d
gene id: 7918:metap1d
uniprot id: W5MLI7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.

7918:srd5a1
gene id: 7918:srd5a1
uniprot id: W5MQI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

7918:atxn3
gene id: 7918:atxn3
uniprot id: W5N5R8
names: Subcellular Location Annotation
messages: Nucleus

7918:zpr1
gene id: 7918:zpr1
uniprot id: W5MEC2
names: Similarity
messages: Belongs to the ZPR1 family.

7918:plekha8
gene id: 7918:plekha8
uniprot id: W5MG90
names: Subcellular Location Annotation
messages: trans-Golgi network membrane

7918:zhx1
gene id: 7918:zhx1
uniprot id: W5MSF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

7918:dtd1
gene id: 7918:dtd1
uniprot id: W5NGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

7918:LOC102687033
gene id: 7918:LOC102687033
uniprot id: W5MMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

7918:aida
gene id: 7918:aida
uniprot id: W5NI16
uniprot id: W5NI17
names: Similarity
messages: Belongs to the AIDA family.

7918:ptpre
gene id: 7918:ptpre
uniprot id: W5MLP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

7918:snx31
gene id: 7918:snx31
uniprot id: W5MTX7
names: Similarity
messages: Belongs to the sorting nexin family.

7918:becn1
gene id: 7918:becn1
uniprot id: W5N032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beclin family.
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: autophagosome
messages: trans-Golgi network membrane

7918:hook2
gene id: 7918:hook2
uniprot id: W5MML1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

7918:rspo4
gene id: 7918:rspo4
uniprot id: W5MKX4
names: Similarity
messages: Belongs to the R-spondin family.

7918:tlr7
gene id: 7918:tlr7
uniprot id: W5MUY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

7918:hip1r
gene id: 7918:hip1r
uniprot id: W5ME89
names: Similarity
messages: Belongs to the SLA2 family.

7918:sema4g
gene id: 7918:sema4g
uniprot id: W5N4K4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102689088
gene id: 7918:LOC102689088
uniprot id: W5M088
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:taz
gene id: 7918:taz
uniprot id: W5NEK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

7918:mrps17
gene id: 7918:mrps17
uniprot id: W5M965
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

7918:lsm2
gene id: 7918:lsm2
uniprot id: W5MD35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

7918:slc25a19
gene id: 7918:slc25a19
uniprot id: W5N703
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:psmb3
gene id: 7918:psmb3
uniprot id: W5N8C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

7918:LOC102684098
gene id: 7918:LOC102684098
uniprot id: W5MAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane

7918:atg9a
gene id: 7918:atg9a
uniprot id: W5MT81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

7918:LOC102696902
gene id: 7918:LOC102696902
uniprot id: W5M7G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

7918:pld4
gene id: 7918:pld4
uniprot id: W5N523
names: Similarity
messages: Belongs to the phospholipase D family.

7918:suclg2
gene id: 7918:suclg2
uniprot id: W5MVN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

7918:ntf3
gene id: 7918:ntf3
uniprot id: W5NKD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

7918:myo1c
gene id: 7918:myo1c
uniprot id: W5MJM2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

7918:rcan3
gene id: 7918:rcan3
uniprot id: W5M4I4
names: Similarity
messages: Belongs to the RCAN family.

7918:smarcb1
gene id: 7918:smarcb1
uniprot id: W5MI82
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

7918:elp2
gene id: 7918:elp2
uniprot id: W5MK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

7918:LOC102696701
gene id: 7918:LOC102696701
uniprot id: W5MDW1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

7918:bcl9
gene id: 7918:bcl9
uniprot id: W5MJ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

7918:nrxn1
gene id: 7918:nrxn1
uniprot id: W5NHH2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:fam162a
gene id: 7918:fam162a
uniprot id: W5M639
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

7918:parpbp
gene id: 7918:parpbp
uniprot id: W5NDG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PARI family.
messages: Cytoplasm
messages: Nucleus

7918:jakmip1
gene id: 7918:jakmip1
uniprot id: W5MVG0
names: Similarity
messages: Belongs to the JAKMIP family.

7918:desi1
gene id: 7918:desi1
uniprot id: W5N0K1
names: Similarity
messages: Belongs to the DeSI family.

7918:scg3
gene id: 7918:scg3
uniprot id: W5N711
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

7918:adprh
gene id: 7918:adprh
uniprot id: W5MWT1
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

7918:rars
gene id: 7918:rars
uniprot id: W5N3M5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

7918:itga6
gene id: 7918:itga6
uniprot id: W5MLC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

7918:dusp8
gene id: 7918:dusp8
uniprot id: W5M085
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

7918:gtf2h5
gene id: 7918:gtf2h5
uniprot id: W5NHF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

7918:slc35d1
gene id: 7918:slc35d1
uniprot id: W5MJH7
names: Subcellular Location Annotation
messages: Membrane

7918:fundc1
gene id: 7918:fundc1
uniprot id: W5M1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

7918:LOC102691742
gene id: 7918:LOC102691742
uniprot id: W5NAA7
names: Similarity
messages: Belongs to the Rab GDI family.

7918:pde9a
gene id: 7918:pde9a
uniprot id: W5M8K2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:LOC102692780
gene id: 7918:LOC102692780
uniprot id: W5M751
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:chat
gene id: 7918:chat
uniprot id: W5MEN0
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

7918:rpl3
gene id: 7918:rpl3
uniprot id: W5MZG8
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

7918:LOC102686698
gene id: 7918:LOC102686698
uniprot id: W5M447
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

7918:slc45a2
gene id: 7918:slc45a2
uniprot id: W5N3F8
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102697245
gene id: 7918:LOC102697245
uniprot id: W5LZF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

7918:abi2
gene id: 7918:abi2
uniprot id: W5MWB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

7918:diras2
gene id: 7918:diras2
uniprot id: W5NLY1
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:LOC102698583
gene id: 7918:LOC102698583
uniprot id: W5MH25
names: Similarity
messages: Belongs to the peptidase S10 family.

7918:ctbp1
gene id: 7918:ctbp1
uniprot id: W5MYK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

7918:caly
gene id: 7918:caly
uniprot id: W5M9U8
names: Similarity
messages: Belongs to the NSG family.

7918:opa1
gene id: 7918:opa1
uniprot id: W5MCD8
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

7918:hsdl1
gene id: 7918:hsdl1
uniprot id: W5NL31
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:arid3b
gene id: 7918:arid3b
uniprot id: W5NDD8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer with ARID3A. Interacts with unphosphorylated RB1.
messages: Nucleus
messages: Transcription factor.

7918:slc39a14
gene id: 7918:slc39a14
uniprot id: W5NEB4
names: Subcellular Location Annotation
messages: Membrane

7918:shkbp1
gene id: 7918:shkbp1
uniprot id: W5NBB1
names: Similarity
messages: Belongs to the KCTD3 family.

7918:rcl1
gene id: 7918:rcl1
uniprot id: W5MVL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Part of the small subunit (SSU) processome, composed of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3.
messages: nucleolus

7918:med28
gene id: 7918:med28
uniprot id: W5M624
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

7918:oprd1
gene id: 7918:oprd1
uniprot id: W5M7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:lgr6
gene id: 7918:lgr6
uniprot id: W5MTU9
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102698328
gene id: 7918:LOC102698328
uniprot id: W5NBA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:rhbdl2
gene id: 7918:rhbdl2
uniprot id: W5MEX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
messages: Membrane

7918:cacng4
gene id: 7918:cacng4
uniprot id: W5N847
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

7918:pcsk6
gene id: 7918:pcsk6
uniprot id: W5N9R2
names: Similarity
messages: Belongs to the peptidase S8 family.

7918:cdkn1a
gene id: 7918:cdkn1a
uniprot id: W5N462
names: Similarity
messages: Belongs to the CDI family.

7918:vps41
gene id: 7918:vps41
uniprot id: W5MZY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

7918:LOC102687218
gene id: 7918:LOC102687218
uniprot id: W5MBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

7918:iapp
gene id: 7918:iapp
uniprot id: W5NE86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
messages: Secreted

7918:pdgfrb
gene id: 7918:pdgfrb
uniprot id: W5MZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:dpt
gene id: 7918:dpt
uniprot id: W5MPW7
names: Similarity
messages: Belongs to the dermatopontin family.

7918:LOC102696484
gene id: 7918:LOC102696484
uniprot id: W5M8G3
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

7918:barx2
gene id: 7918:barx2
uniprot id: W5M3B0
names: Subcellular Location Annotation
messages: Nucleus

7918:tmem136
gene id: 7918:tmem136
uniprot id: W5M224
names: Subcellular Location Annotation
messages: Membrane

7918:slc4a1
gene id: 7918:slc4a1
uniprot id: W5N2L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

7918:etv7
gene id: 7918:etv7
uniprot id: W5MX12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:unc50
gene id: 7918:unc50
uniprot id: W5M0G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

7918:slc15a2
gene id: 7918:slc15a2
uniprot id: W5M300
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.

7918:entpd6
gene id: 7918:entpd6
uniprot id: W5NJD9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

7918:kif3c
gene id: 7918:kif3c
uniprot id: W5NHP0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:pgls
gene id: 7918:pgls
uniprot id: W5MPW5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

7918:uba1
gene id: 7918:uba1
uniprot id: W5NAJ3
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

7918:lhx3
gene id: 7918:lhx3
uniprot id: W5M8B6
names: Subcellular Location Annotation
messages: Nucleus

7918:gad2
gene id: 7918:gad2
uniprot id: W5MLV0
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

7918:ndufb7
gene id: 7918:ndufb7
uniprot id: W5MUW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

7918:LOC102690618
gene id: 7918:LOC102690618
uniprot id: W5LZM0
names: Subcellular Location Annotation
messages: Nucleus

7918:kif3b
gene id: 7918:kif3b
uniprot id: W5MF46
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:bicc1
gene id: 7918:bicc1
uniprot id: W5MHJ8
names: Similarity
messages: Belongs to the BicC family.

7918:fam83g
gene id: 7918:fam83g
uniprot id: W5MF74
names: Similarity
messages: Belongs to the FAM83 family.

7918:atp6v1b1
gene id: 7918:atp6v1b1
uniprot id: W5M0G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

7918:acy1
gene id: 7918:acy1
uniprot id: W5NA85
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm

7918:hs3st2
gene id: 7918:hs3st2
uniprot id: W5M8G8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

7918:igfbp6
gene id: 7918:igfbp6
uniprot id: W5M8T4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:mrpl47
gene id: 7918:mrpl47
uniprot id: W5LZA3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

7918:snx3
gene id: 7918:snx3
uniprot id: W5NIP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

7918:ero1a
gene id: 7918:ero1a
uniprot id: W5N2H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

7918:kif21b
gene id: 7918:kif21b
uniprot id: W5MZF1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:mtx2
gene id: 7918:mtx2
uniprot id: W5MJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

7918:csnk2a1
gene id: 7918:csnk2a1
uniprot id: W5M2F4
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:nfxl1
gene id: 7918:nfxl1
uniprot id: W5N2A9
names: Similarity
messages: Belongs to the NFX1 family.

7918:ccdc22
gene id: 7918:ccdc22
uniprot id: W5NAZ6
names: Similarity
messages: Belongs to the CCDC22 family.

7918:recql5
gene id: 7918:recql5
uniprot id: W5N0H1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

7918:ints10
gene id: 7918:ints10
uniprot id: W5N5D8
uniprot id: W5N5E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

7918:nup50
gene id: 7918:nup50
uniprot id: W5NIG0
names: Subcellular Location Annotation
messages: nuclear pore complex

7918:fam150a
gene id: 7918:fam150a
uniprot id: W5MF77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

7918:sh3pxd2a
gene id: 7918:sh3pxd2a
uniprot id: W5N250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm

7918:kdelr2
gene id: 7918:kdelr2
uniprot id: W5MP65
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:tmem178b
gene id: 7918:tmem178b
uniprot id: W5NGW0
names: Similarity
messages: Belongs to the TMEM178 family.

7918:LOC102682995
gene id: 7918:LOC102682995
uniprot id: W5MJQ3
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

7918:LOC102693186
gene id: 7918:LOC102693186
uniprot id: W5M7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

7918:inadl
gene id: 7918:inadl
uniprot id: W5MUV5
names: Subcellular Location Annotation
messages: tight junction

7918:mrps16
gene id: 7918:mrps16
uniprot id: W5M8I4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

7918:nov
gene id: 7918:nov
uniprot id: W5MRV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:emx2
gene id: 7918:emx2
uniprot id: W5MTY2
names: Subcellular Location Annotation
messages: Nucleus

7918:mdh1b
gene id: 7918:mdh1b
uniprot id: W5MWJ0
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

7918:LOC102693174
gene id: 7918:LOC102693174
uniprot id: W5MI12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

7918:wnt3
gene id: 7918:wnt3
uniprot id: W5N5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:sphkap
gene id: 7918:sphkap
uniprot id: W5MNS3
names: Similarity
messages: Belongs to the AKAP110 family.

7918:mon1a
gene id: 7918:mon1a
uniprot id: W5MY90
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

7918:maml3
gene id: 7918:maml3
uniprot id: W5MWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

7918:abhd15
gene id: 7918:abhd15
uniprot id: W5MHM8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

7918:ino80
gene id: 7918:ino80
uniprot id: W5N3E8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

7918:map3k7
gene id: 7918:map3k7
uniprot id: W5NK00
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

7918:LOC102696796
gene id: 7918:LOC102696796
uniprot id: W5M8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

7918:fam161b
gene id: 7918:fam161b
uniprot id: W5MYQ2
names: Similarity
messages: Belongs to the FAM161 family.

7918:LOC102688707
gene id: 7918:LOC102688707
uniprot id: W5N5S4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:churc1
gene id: 7918:churc1
uniprot id: W5N7Q1
names: Similarity
messages: Belongs to the Churchill family.

7918:LOC102685098
gene id: 7918:LOC102685098
uniprot id: W5NG92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

7918:ndufs5
gene id: 7918:ndufs5
uniprot id: W5LYV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

7918:st7
gene id: 7918:st7
uniprot id: W5NEY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

7918:farsb
gene id: 7918:farsb
uniprot id: W5M995
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

7918:trappc2l
gene id: 7918:trappc2l
uniprot id: W5MBA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network
messages: perinuclear region

7918:akt1
gene id: 7918:akt1
uniprot id: W5N501
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

7918:LOC102684264
gene id: 7918:LOC102684264
uniprot id: W5N2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KLHL3 family.
messages: cytoskeleton
messages: cytosol

7918:hsp90b1
gene id: 7918:hsp90b1
uniprot id: W5NCY3
names: Similarity
messages: Belongs to the heat shock protein 90 family.

7918:tcp1
gene id: 7918:tcp1
uniprot id: W5NH57
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

7918:tenm3
gene id: 7918:tenm3
uniprot id: W5N892
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:atp1b4
gene id: 7918:atp1b4
uniprot id: W5NDQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

7918:wnt5b
gene id: 7918:wnt5b
uniprot id: W5NIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:exoc6b
gene id: 7918:exoc6b
uniprot id: W5LZA5
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

7918:KEF94 p02
gene id: 7918:KEF94_p02
uniprot id: Q8HQM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

7918:LOC102695882
gene id: 7918:LOC102695882
uniprot id: W5NGJ2
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

7918:hsf1
gene id: 7918:hsf1
uniprot id: W5MKU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

7918:LOC102693904
gene id: 7918:LOC102693904
uniprot id: W5MNH1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:il10
gene id: 7918:il10
uniprot id: W5N369
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

7918:vps37c
gene id: 7918:vps37c
uniprot id: W5MNJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

7918:gtdc1
gene id: 7918:gtdc1
uniprot id: W5LZ99
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

7918:tmem18
gene id: 7918:tmem18
uniprot id: W5NL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

7918:hsd17b2
gene id: 7918:hsd17b2
uniprot id: W5M2B9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:coq10b
gene id: 7918:coq10b
uniprot id: W5M8H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

7918:tnfrsf11b
gene id: 7918:tnfrsf11b
uniprot id: W5MRR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:snx17
gene id: 7918:snx17
uniprot id: W5NJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

7918:ndrg4
gene id: 7918:ndrg4
uniprot id: W5M6G7
names: Similarity
messages: Belongs to the NDRG family.

7918:LOC102694593
gene id: 7918:LOC102694593
uniprot id: W5N9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

7918:myog
gene id: 7918:myog
uniprot id: W5MXM9
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

7918:LOC102685189
gene id: 7918:LOC102685189
uniprot id: W5N822
names: Similarity
messages: Belongs to the DNase I family.

7918:LOC102697612
gene id: 7918:LOC102697612
uniprot id: W5MPF5
names: Subcellular Location Annotation
messages: Secreted

7918:stk38l
gene id: 7918:stk38l
uniprot id: W5NDM4
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:rap2b
gene id: 7918:rap2b
uniprot id: W5NLH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

7918:uros
gene id: 7918:uros
uniprot id: W5MMG7
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

7918:tdo2
gene id: 7918:tdo2
uniprot id: W5MNP8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:xylt1
gene id: 7918:xylt1
uniprot id: W5MJC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

7918:gpr68
gene id: 7918:gpr68
uniprot id: W5NMG3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:LOC102685890
gene id: 7918:LOC102685890
uniprot id: W5MP49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

7918:ldlr
gene id: 7918:ldlr
uniprot id: W5MM69
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:eef2k
gene id: 7918:eef2k
uniprot id: W5MNS9
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

7918:slc39a8
gene id: 7918:slc39a8
uniprot id: W5N2M8
names: Subcellular Location Annotation
messages: Membrane

7918:rnf170
gene id: 7918:rnf170
uniprot id: W5M630
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:cryab
gene id: 7918:cryab
uniprot id: W5LZU6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

7918:pif1
gene id: 7918:pif1
uniprot id: W5M9E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.
messages: Mitochondrion
messages: Monomer.
messages: Nucleus

7918:raly
gene id: 7918:raly
uniprot id: W5MK27
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

7918:actr6
gene id: 7918:actr6
uniprot id: W5NDF3
names: Similarity
messages: Belongs to the actin family.

7918:LOC102683823
gene id: 7918:LOC102683823
uniprot id: W5N692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

7918:stam
gene id: 7918:stam
uniprot id: W5MYF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

7918:hmgcl
gene id: 7918:hmgcl
uniprot id: W5M118
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

7918:b3galnt2
gene id: 7918:b3galnt2
uniprot id: W5NG13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:abcb7
gene id: 7918:abcb7
uniprot id: W5N873
names: Subcellular Location Annotation
messages: Membrane

7918:cln5
gene id: 7918:cln5
uniprot id: W5MGC2
names: Similarity
messages: Belongs to the CLN5 family.

7918:fzd9
gene id: 7918:fzd9
uniprot id: W5NMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

7918:adssl1
gene id: 7918:adssl1
uniprot id: W5N4X1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

7918:nodal
gene id: 7918:nodal
uniprot id: W5MCN4
names: Similarity
messages: Belongs to the TGF-beta family.

7918:cmpk2
gene id: 7918:cmpk2
uniprot id: W5NJG5
names: Similarity
messages: Belongs to the thymidylate kinase family.

7918:arpc3
gene id: 7918:arpc3
uniprot id: W5MK48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

7918:ncbp3
gene id: 7918:ncbp3
uniprot id: W5MI94
names: Similarity
messages: Belongs to the NCBP3 family.

7918:htr5a
gene id: 7918:htr5a
uniprot id: W5N445
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:pigh
gene id: 7918:pigh
uniprot id: W5N3H0
names: Similarity
messages: Belongs to the PIGH family.

7918:eda2r
gene id: 7918:eda2r
uniprot id: W5NBP3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:lage3
gene id: 7918:lage3
uniprot id: W5NEX3
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

7918:LOC102691383
gene id: 7918:LOC102691383
uniprot id: W5NGU4
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

7918:LOC107076905
gene id: 7918:LOC107076905
uniprot id: W5N9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:mfsd14a
gene id: 7918:mfsd14a
uniprot id: W5MT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

7918:nrg2
gene id: 7918:nrg2
uniprot id: W5N4J3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:LOC102692279
gene id: 7918:LOC102692279
uniprot id: W5N438
names: Similarity
messages: Belongs to the DCK/DGK family.

7918:tspan13
gene id: 7918:tspan13
uniprot id: W5MZV5
names: Subcellular Location Annotation
messages: Membrane

7918:mmp11
gene id: 7918:mmp11
uniprot id: W5MI10
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

7918:LOC102685508
gene id: 7918:LOC102685508
uniprot id: W5N1C1
names: Similarity
messages: Belongs to the peptidase A1 family.

7918:nid2
gene id: 7918:nid2
uniprot id: W5N2B6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

7918:LOC102682611
gene id: 7918:LOC102682611
uniprot id: W5M8Z6
names: Similarity
messages: Belongs to the pro/parathymosin family.

7918:vps26a
gene id: 7918:vps26a
uniprot id: W5MRZ6
names: Similarity
messages: Belongs to the VPS26 family.

7918:LOC102693289
gene id: 7918:LOC102693289
uniprot id: W5N540
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:LOC107079423
gene id: 7918:LOC107079423
uniprot id: W5M848
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

7918:isoc1
gene id: 7918:isoc1
uniprot id: W5MP11
names: Similarity
messages: Belongs to the isochorismatase family.

7918:osbpl6
gene id: 7918:osbpl6
uniprot id: W5MIR8
names: Similarity
messages: Belongs to the OSBP family.

7918:LOC102698415
gene id: 7918:LOC102698415
uniprot id: W5MZI0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

7918:lhx6
gene id: 7918:lhx6
uniprot id: W5M563
names: Subcellular Location Annotation
messages: Nucleus

7918:atp2c2
gene id: 7918:atp2c2
uniprot id: W5M462
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:naa35
gene id: 7918:naa35
uniprot id: W5M338
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

7918:LOC102698456
gene id: 7918:LOC102698456
uniprot id: W5MKV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:fh
gene id: 7918:fh
uniprot id: W5NIM8
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

7918:tm9sf2
gene id: 7918:tm9sf2
uniprot id: W5M5T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

7918:LOC102694308
gene id: 7918:LOC102694308
uniprot id: W5N2J7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

7918:elmo1
gene id: 7918:elmo1
uniprot id: W5MJP2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

7918:dnajb14
gene id: 7918:dnajb14
uniprot id: W5N342
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:terf1
gene id: 7918:terf1
uniprot id: W5M814
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus

7918:drd5
gene id: 7918:drd5
uniprot id: W5NNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:LOC102692580
gene id: 7918:LOC102692580
uniprot id: W5NNR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

7918:kpna6
gene id: 7918:kpna6
uniprot id: W5M2Y3
names: Similarity
messages: Belongs to the importin alpha family.

7918:ereg
gene id: 7918:ereg
uniprot id: W5N2H3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:fbln1
gene id: 7918:fbln1
uniprot id: W5NK75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:nnt
gene id: 7918:nnt
uniprot id: W5N3B2
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

7918:camk2n2
gene id: 7918:camk2n2
uniprot id: W5MFR9
names: Similarity
messages: Belongs to the CAMK2N family.

7918:mettl14
gene id: 7918:mettl14
uniprot id: W5M6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MT-A70-like family.
messages: Heterodimer; heterodimerizes with mettl3 to form an antiparallel heterodimer that constitutes an active methyltransferase.
messages: Nucleus
messages: The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with mettl3, mettl14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing.

7918:hmgcr
gene id: 7918:hmgcr
uniprot id: W5MDU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

7918:aar2
gene id: 7918:aar2
uniprot id: W5MBL6
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

7918:tada1
gene id: 7918:tada1
uniprot id: W5MWV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

7918:usp14
gene id: 7918:usp14
uniprot id: W5M1Z1
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

7918:prom2
gene id: 7918:prom2
uniprot id: W5NE32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

7918:thumpd3
gene id: 7918:thumpd3
uniprot id: W5MUB7
names: Similarity
messages: Belongs to the methyltransferase superfamily.

7918:LOC102697730
gene id: 7918:LOC102697730
uniprot id: W5NA87
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102685877
gene id: 7918:LOC102685877
uniprot id: W5MW93
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:slc9a7
gene id: 7918:slc9a7
uniprot id: W5MNB8
uniprot id: W5MND3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

7918:cdh20
gene id: 7918:cdh20
uniprot id: W5N5E5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

7918:LOC102688611
gene id: 7918:LOC102688611
uniprot id: W5M4Y3
names: Similarity
messages: Belongs to the phospholipase D family.

7918:bcap29
gene id: 7918:bcap29
uniprot id: W5NFQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

7918:top2b
gene id: 7918:top2b
uniprot id: W5MJ16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

7918:slc48a1
gene id: 7918:slc48a1
uniprot id: W5MD39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

7918:tfap2b
gene id: 7918:tfap2b
uniprot id: W5NHR2
names: Similarity
messages: Belongs to the AP-2 family.

7918:aes
gene id: 7918:aes
uniprot id: W5MH46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

7918:hn1
gene id: 7918:hn1
uniprot id: W5N762
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

7918:gfap
gene id: 7918:gfap
uniprot id: W5N1M7
names: Similarity
messages: Belongs to the intermediate filament family.

7918:LOC102696823
gene id: 7918:LOC102696823
uniprot id: W5N6V4
names: Similarity
messages: Belongs to the BolA/IbaG family.

7918:psme4
gene id: 7918:psme4
uniprot id: W5NHE8
names: Similarity
messages: Belongs to the BLM10 family.

7918:atp6v1f
gene id: 7918:atp6v1f
uniprot id: W5NEW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

7918:mmp16
gene id: 7918:mmp16
uniprot id: W5MWJ7
uniprot id: W5MWK7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

7918:chrnd
gene id: 7918:chrnd
uniprot id: W5MFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:man1a1
gene id: 7918:man1a1
uniprot id: W5NL25
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

7918:wtap
gene id: 7918:wtap
uniprot id: W5NH48
names: Similarity
messages: Belongs to the fl(2)d family.

7918:inpp5d
gene id: 7918:inpp5d
uniprot id: W5MDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

7918:me3
gene id: 7918:me3
uniprot id: W5MTP7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

7918:tm4sf20
gene id: 7918:tm4sf20
uniprot id: W5MTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

7918:grk6
gene id: 7918:grk6
uniprot id: W5N3I3
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

7918:dennd6b
gene id: 7918:dennd6b
uniprot id: W5NJE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Recycling endosome

7918:mmd
gene id: 7918:mmd
uniprot id: W5N344
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

7918:rap1b
gene id: 7918:rap1b
uniprot id: W5NH34
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:dram1
gene id: 7918:dram1
uniprot id: W5NDH2
names: Subcellular Location Annotation
messages: Membrane

7918:syndig1
gene id: 7918:syndig1
uniprot id: W5NJG3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

7918:cldn7
gene id: 7918:cldn7
uniprot id: W5N8P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:kcnt2
gene id: 7918:kcnt2
uniprot id: W5MKV6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:rbm48
gene id: 7918:rbm48
uniprot id: W5MXI0
names: Function
names: Similarity
messages: As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
messages: Belongs to the RBM48 family.

7918:LOC102686811
gene id: 7918:LOC102686811
uniprot id: W5MWH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

7918:tacr2
gene id: 7918:tacr2
uniprot id: W5MS85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:th
gene id: 7918:th
uniprot id: W5M177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

7918:dzip1
gene id: 7918:dzip1
uniprot id: W5MCM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: cilium basal body

7918:utrn
gene id: 7918:utrn
uniprot id: W5NH18
names: Function
names: Subcellular Location Annotation
messages: May play a role in anchoring the cytoskeleton to the plasma membrane.
messages: cytoskeleton

7918:uhrf2
gene id: 7918:uhrf2
uniprot id: W5MV89
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

7918:skor2
gene id: 7918:skor2
uniprot id: W5N3R2
names: Similarity
messages: Belongs to the SKI family.

7918:ift43
gene id: 7918:ift43
uniprot id: W5MX77
uniprot id: W5MX88
names: Similarity
messages: Belongs to the IFT43 family.

7918:kcnj5
gene id: 7918:kcnj5
uniprot id: W5M3W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

7918:gmppa
gene id: 7918:gmppa
uniprot id: W5LXI7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

7918:fam126b
gene id: 7918:fam126b
uniprot id: W5MUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Hyccin family.
messages: Cell membrane
messages: Membrane
messages: cytosol

7918:lin9
gene id: 7918:lin9
uniprot id: W5NFN8
names: Similarity
messages: Belongs to the lin-9 family.

7918:LOC102691668
gene id: 7918:LOC102691668
uniprot id: W5MQ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

7918:mff
gene id: 7918:mff
uniprot id: W5MTQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

7918:cnih3
gene id: 7918:cnih3
uniprot id: W5NG41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

7918:habp4
gene id: 7918:habp4
uniprot id: W5MS54
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

7918:LOC102690400
gene id: 7918:LOC102690400
uniprot id: W5N023
names: Similarity
messages: Belongs to the BicC family.

7918:srp9
gene id: 7918:srp9
uniprot id: W5NG24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

7918:golt1b
gene id: 7918:golt1b
uniprot id: W5NE79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

7918:ppef2
gene id: 7918:ppef2
uniprot id: W5M8R5
names: Similarity
messages: Belongs to the PPP phosphatase family.

7918:pck1
gene id: 7918:pck1
uniprot id: W5MJT2
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

7918:cdo1
gene id: 7918:cdo1
uniprot id: W5MR64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

7918:prdm12
gene id: 7918:prdm12
uniprot id: W5MDT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

7918:LOC102682643
gene id: 7918:LOC102682643
uniprot id: W5NDH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium

7918:srp19
gene id: 7918:srp19
uniprot id: W5MW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm

7918:anpep
gene id: 7918:anpep
uniprot id: W5NB25
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

7918:elof1
gene id: 7918:elof1
uniprot id: W5MNE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

7918:spsb4
gene id: 7918:spsb4
uniprot id: W5M9N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

7918:zic3
gene id: 7918:zic3
uniprot id: W5NDE1
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

7918:st7l
gene id: 7918:st7l
uniprot id: W5MW97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

7918:jak1
gene id: 7918:jak1
uniprot id: W5MIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

7918:LOC102694972
gene id: 7918:LOC102694972
uniprot id: W5M8W9
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

7918:acp1
gene id: 7918:acp1
uniprot id: W5NL04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

7918:man1a2
gene id: 7918:man1a2
uniprot id: W5MZ14
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

7918:syncrip
gene id: 7918:syncrip
uniprot id: W5NJV6
names: Subcellular Location Annotation
messages: Cytoplasm

7918:cdk14
gene id: 7918:cdk14
uniprot id: W5MX19
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:LOC102697476
gene id: 7918:LOC102697476
uniprot id: W5M1K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

7918:LOC102697293
gene id: 7918:LOC102697293
uniprot id: W5NAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

7918:LOC102686674
gene id: 7918:LOC102686674
uniprot id: W5M1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

7918:ralyl
gene id: 7918:ralyl
uniprot id: W5N524
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

7918:clg10h17orf62
gene id: 7918:clg10h17orf62
uniprot id: W5N1H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:runx1
gene id: 7918:runx1
uniprot id: W5MYN0
names: Subcellular Location Annotation
messages: Nucleus

7918:meaf6
gene id: 7918:meaf6
uniprot id: W5MF92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

7918:LOC102686449
gene id: 7918:LOC102686449
uniprot id: W5MC07
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102692770
gene id: 7918:LOC102692770
uniprot id: W5MLZ3
names: Similarity
messages: Belongs to the globin family.

7918:LOC102685658
gene id: 7918:LOC102685658
uniprot id: W5MRG0
names: Subcellular Location Annotation
messages: Cytoplasm

7918:ppp2r3c
gene id: 7918:ppp2r3c
uniprot id: W5MS39
names: Subcellular Location Annotation
messages: Nucleus

7918:cpne2
gene id: 7918:cpne2
uniprot id: W5MM07
names: Similarity
messages: Belongs to the copine family.

7918:thrb
gene id: 7918:thrb
uniprot id: W5MIS2
uniprot id: W5MIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

7918:psmg2
gene id: 7918:psmg2
uniprot id: W5MTQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

7918:LOC102693226
gene id: 7918:LOC102693226
uniprot id: W5NH59
names: Similarity
messages: Belongs to the peptidase A1 family.

7918:zdhhc12
gene id: 7918:zdhhc12
uniprot id: W5MG21
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

7918:sfrp1
gene id: 7918:sfrp1
uniprot id: W5NEE1
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:uhrf1
gene id: 7918:uhrf1
uniprot id: W5LVF4
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications.
messages: Nucleus
messages: The YDG domain mediates the interaction with histone H3.
messages: The tudor-like regions specifically recognize and bind histone H3 unmethylated at 'Arg-2' (H3R2me0), while the PHD-type zinc finger specifically recognizes and binds histone H3 trimethylated at 'Lys-9' (H3K9me3).

7918:med27
gene id: 7918:med27
uniprot id: W5M9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 27 family.
messages: Nucleus

7918:LOC102683198
gene id: 7918:LOC102683198
uniprot id: W5MK26
uniprot id: W5MK40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

7918:spata18
gene id: 7918:spata18
uniprot id: W5N9S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

7918:LOC102684715
gene id: 7918:LOC102684715
uniprot id: W5N741
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

7918:LOC102691675
gene id: 7918:LOC102691675
uniprot id: W5N4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

7918:mlf1
gene id: 7918:mlf1
uniprot id: W5M841
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

7918:mettl6
gene id: 7918:mettl6
uniprot id: W5M191
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

7918:LOC102686793
gene id: 7918:LOC102686793
uniprot id: W5LZ24
names: Similarity
messages: Belongs to the intermediate filament family.

7918:LOC102692059
gene id: 7918:LOC102692059
uniprot id: W5MI70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

7918:tonsl
gene id: 7918:tonsl
uniprot id: W5MF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tonsoku family.
messages: Chromosome

7918:bbs2
gene id: 7918:bbs2
uniprot id: W5MMG5
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

7918:il17b
gene id: 7918:il17b
uniprot id: W5MS55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

7918:ddx54
gene id: 7918:ddx54
uniprot id: W5MPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: nucleolus

7918:LOC107079013
gene id: 7918:LOC107079013
uniprot id: W5ME94
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:mrpl43
gene id: 7918:mrpl43
uniprot id: W5N4I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

7918:trappc2
gene id: 7918:trappc2
uniprot id: W5MV58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

7918:nxt2
gene id: 7918:nxt2
uniprot id: W5NB64
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

7918:ctso
gene id: 7918:ctso
uniprot id: W5MNN3
names: Similarity
messages: Belongs to the peptidase C1 family.

7918:nkain3
gene id: 7918:nkain3
uniprot id: W5MC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

7918:ost4
gene id: 7918:ost4
uniprot id: W5NN86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:impa2
gene id: 7918:impa2
uniprot id: W5M287
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

7918:far1
gene id: 7918:far1
uniprot id: W5M9K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

7918:LOC102694223
gene id: 7918:LOC102694223
uniprot id: W5NFW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

7918:sin3b
gene id: 7918:sin3b
uniprot id: W5LVE3
names: Subcellular Location Annotation
messages: Nucleus

7918:gpr34
gene id: 7918:gpr34
uniprot id: W5NML5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:mad1l1
gene id: 7918:mad1l1
uniprot id: W5LZN2
names: Similarity
messages: Belongs to the MAD1 family.

7918:kif26b
gene id: 7918:kif26b
uniprot id: W5NIV7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:hs2st1
gene id: 7918:hs2st1
uniprot id: W5MCS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:homer2
gene id: 7918:homer2
uniprot id: W5N5N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

7918:sema3c
gene id: 7918:sema3c
uniprot id: W5NGI4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:imp3
gene id: 7918:imp3
uniprot id: W5MVX8
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

7918:gcnt2
gene id: 7918:gcnt2
uniprot id: W5N6I1
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

7918:tbcb
gene id: 7918:tbcb
uniprot id: W5NCB8
names: Similarity
messages: Belongs to the TBCB family.

7918:dlx5
gene id: 7918:dlx5
uniprot id: W5MYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

7918:utp14a
gene id: 7918:utp14a
uniprot id: W5NDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

7918:grpr
gene id: 7918:grpr
uniprot id: W5MM74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:asic2
gene id: 7918:asic2
uniprot id: W5N2C1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:gpr155
gene id: 7918:gpr155
uniprot id: W5MKI0
names: Subcellular Location Annotation
messages: Membrane

7918:gucy1a2
gene id: 7918:gucy1a2
uniprot id: W5MIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

7918:LOC102685937
gene id: 7918:LOC102685937
uniprot id: W5N1Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:cspg4
gene id: 7918:cspg4
uniprot id: W5NA89
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ccnt2
gene id: 7918:ccnt2
uniprot id: W5M0Y3
names: Similarity
messages: Belongs to the cyclin family.

7918:grk5
gene id: 7918:grk5
uniprot id: W5N033
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

7918:nkx1-1
gene id: 7918:nkx1-1
uniprot id: W5MYN2
names: Subcellular Location Annotation
messages: Nucleus

7918:adtrp
gene id: 7918:adtrp
uniprot id: W5MMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

7918:grhl1
gene id: 7918:grhl1
uniprot id: W5NJJ9
names: Subcellular Location Annotation
messages: Nucleus

7918:slc2a9
gene id: 7918:slc2a9
uniprot id: W5MUU4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

7918:katnb1
gene id: 7918:katnb1
uniprot id: W5MGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat KATNB1 family.
messages: Cytoplasm
messages: Interacts with KATNA1. This interaction enhances the microtubule binding and severing activity of KATNA1 and also targets this activity to the centrosome.
messages: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

7918:march9
gene id: 7918:march9
uniprot id: W5M8G6
names: Subcellular Location Annotation
messages: Membrane

7918:pax6
gene id: 7918:pax6
uniprot id: W5MAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

7918:mapk6
gene id: 7918:mapk6
uniprot id: W5N745
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

7918:kdr
gene id: 7918:kdr
uniprot id: W5NA10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

7918:tmod1
gene id: 7918:tmod1
uniprot id: W5N009
names: Subcellular Location Annotation
messages: cytoskeleton

7918:cry1
gene id: 7918:cry1
uniprot id: W5NDT4
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

7918:npc1
gene id: 7918:npc1
uniprot id: W5M0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

7918:strip2
gene id: 7918:strip2
uniprot id: W5NG89
names: Similarity
messages: Belongs to the STRIP family.

7918:clstn3
gene id: 7918:clstn3
uniprot id: W5MLW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

7918:kdm6a
gene id: 7918:kdm6a
uniprot id: W5M1D4
uniprot id: W5M1F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTX family.
messages: Nucleus

7918:LOC102699254
gene id: 7918:LOC102699254
uniprot id: W5NLM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

7918:LOC102687541
gene id: 7918:LOC102687541
uniprot id: W5NBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

7918:itgb6
gene id: 7918:itgb6
uniprot id: W5MQ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

7918:arid3a
gene id: 7918:arid3a
uniprot id: W5M355
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer.
messages: Nucleus
messages: Transcription factor.

7918:riok3
gene id: 7918:riok3
uniprot id: W5M0N7
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

7918:lamp1
gene id: 7918:lamp1
uniprot id: W5MUH1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

7918:LOC102695672
gene id: 7918:LOC102695672
uniprot id: W5MLL8
names: Subcellular Location Annotation
messages: Membrane

7918:smc3
gene id: 7918:smc3
uniprot id: W5N3G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

7918:foxp3
gene id: 7918:foxp3
uniprot id: W5NAV2
names: Subcellular Location Annotation
messages: Nucleus

7918:gata1
gene id: 7918:gata1
uniprot id: W5NC15
names: Subcellular Location Annotation
messages: Nucleus

7918:porcn
gene id: 7918:porcn
uniprot id: W5NAL5
names: Subcellular Location Annotation
messages: Membrane

7918:crybb2
gene id: 7918:crybb2
uniprot id: W5M599
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

7918:etfa
gene id: 7918:etfa
uniprot id: W5NBV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

7918:ggt7
gene id: 7918:ggt7
uniprot id: W5MAI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

7918:crabp1
gene id: 7918:crabp1
uniprot id: W5ND13
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

7918:LOC102690982
gene id: 7918:LOC102690982
uniprot id: W5NCZ3
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102695725
gene id: 7918:LOC102695725
uniprot id: W5M6T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

7918:lamb4
gene id: 7918:lamb4
uniprot id: W5NG29
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

7918:atp10d
gene id: 7918:atp10d
uniprot id: W5N152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

7918:gins3
gene id: 7918:gins3
uniprot id: W5M6E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

7918:csnk1a1
gene id: 7918:csnk1a1
uniprot id: W5N2N1
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:LOC102696239
gene id: 7918:LOC102696239
uniprot id: W5MWS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

7918:mogat3
gene id: 7918:mogat3
uniprot id: W5N803
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

7918:sgol2
gene id: 7918:sgol2
uniprot id: W5M884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

7918:LOC102696443
gene id: 7918:LOC102696443
uniprot id: W5MNQ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:mogat2
gene id: 7918:mogat2
uniprot id: W5MB89
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:frem1
gene id: 7918:frem1
uniprot id: W5MYY6
names: Similarity
messages: Belongs to the FRAS1 family.

7918:cdc73
gene id: 7918:cdc73
uniprot id: W5MKT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

7918:ska1
gene id: 7918:ska1
uniprot id: W5N5A0
names: Similarity
messages: Belongs to the SKA1 family.

7918:gpkow
gene id: 7918:gpkow
uniprot id: W5NC37
uniprot id: W5NC39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus
messages: RNA-binding protein involved in pre-mRNA splicing.

7918:epha4
gene id: 7918:epha4
uniprot id: W5M9H5
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

7918:LOC107077303
gene id: 7918:LOC107077303
uniprot id: W5MAQ1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

7918:LOC102695287
gene id: 7918:LOC102695287
uniprot id: W5LXR4
names: Subcellular Location Annotation
messages: extracellular space

7918:cacnb2
gene id: 7918:cacnb2
uniprot id: W5MY77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: sarcolemma

7918:ncoa3
gene id: 7918:ncoa3
uniprot id: W5M8R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

7918:vopp1
gene id: 7918:vopp1
uniprot id: W5MXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

7918:nus1
gene id: 7918:nus1
uniprot id: W5NKN3
names: Similarity
messages: Belongs to the UPP synthase family.

7918:LOC102683448
gene id: 7918:LOC102683448
uniprot id: W5NP42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:clstn1
gene id: 7918:clstn1
uniprot id: W5MIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

7918:rnaset2
gene id: 7918:rnaset2
uniprot id: W5NJI8
names: Similarity
messages: Belongs to the RNase T2 family.

7918:dnah5
gene id: 7918:dnah5
uniprot id: W5LXA4
names: Similarity
messages: Belongs to the dynein heavy chain family.

7918:p2ry1
gene id: 7918:p2ry1
uniprot id: W5NLH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:hoxa11
gene id: 7918:hoxa11
uniprot id: W5N1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

7918:LOC102699198
gene id: 7918:LOC102699198
uniprot id: W5LYQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-12B family.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Secreted

7918:tubg1
gene id: 7918:tubg1
uniprot id: W5N3U4
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

7918:slc25a13
gene id: 7918:slc25a13
uniprot id: W5MYM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

7918:eif3b
gene id: 7918:eif3b
uniprot id: W5M9I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

7918:ddx55
gene id: 7918:ddx55
uniprot id: W5MF80
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

7918:areg
gene id: 7918:areg
uniprot id: W5N2I2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:elovl2
gene id: 7918:elovl2
uniprot id: W5N6B7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL2 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

7918:ggt5
gene id: 7918:ggt5
uniprot id: W5MC95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

7918:LOC102684941
gene id: 7918:LOC102684941
uniprot id: W5LZF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

7918:otp
gene id: 7918:otp
uniprot id: W5MEZ9
names: Subcellular Location Annotation
messages: Nucleus

7918:ptpn13
gene id: 7918:ptpn13
uniprot id: W5N2F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

7918:LOC102684566
gene id: 7918:LOC102684566
uniprot id: W5LW35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

7918:trabd2a
gene id: 7918:trabd2a
uniprot id: W5M681
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

7918:psmd5
gene id: 7918:psmd5
uniprot id: W5M622
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

7918:ctse
gene id: 7918:ctse
uniprot id: W5N4U9
names: Similarity
messages: Belongs to the peptidase A1 family.

7918:tardbp
gene id: 7918:tardbp
uniprot id: W5MHW9
names: Subcellular Location Annotation
messages: Nucleus

7918:ap1s3
gene id: 7918:ap1s3
uniprot id: W5M8Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

7918:sox21
gene id: 7918:sox21
uniprot id: W5NMM8
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102685227
gene id: 7918:LOC102685227
uniprot id: W5NHR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

7918:caskin1
gene id: 7918:caskin1
uniprot id: W5MEY2
names: Subcellular Location Annotation
messages: Cytoplasm

7918:psap
gene id: 7918:psap
uniprot id: W5MQ57
names: Function
names: Subcellular Location Annotation
messages: Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
messages: Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
messages: Secreted

7918:LOC102691070
gene id: 7918:LOC102691070
uniprot id: W5MM50
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

7918:pou3f1
gene id: 7918:pou3f1
uniprot id: W5NP34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

7918:csnk2a2
gene id: 7918:csnk2a2
uniprot id: W5M7Q7
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:dyx1c1
gene id: 7918:dyx1c1
uniprot id: W5N7K3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Dynein axonemal particle
messages: neuron projection

7918:alg2
gene id: 7918:alg2
uniprot id: W5MDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

7918:mmp24
gene id: 7918:mmp24
uniprot id: W5MM00
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

7918:faslg
gene id: 7918:faslg
uniprot id: W5MWU1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

7918:lyrm4
gene id: 7918:lyrm4
uniprot id: W5N120
names: Similarity
messages: Belongs to the complex I LYR family.

7918:lyrm9
gene id: 7918:lyrm9
uniprot id: W5MEL0
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

7918:crat
gene id: 7918:crat
uniprot id: W5M2G0
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

7918:cnnm2
gene id: 7918:cnnm2
uniprot id: W5N1E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

7918:foxb2
gene id: 7918:foxb2
uniprot id: W5NLY5
names: Subcellular Location Annotation
messages: Nucleus

7918:pappa
gene id: 7918:pappa
uniprot id: W5MBC1
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:eda
gene id: 7918:eda
uniprot id: W5NBV4
names: Similarity
messages: Belongs to the tumor necrosis factor family.

7918:mcm2
gene id: 7918:mcm2
uniprot id: W5N7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

7918:srpx
gene id: 7918:srpx
uniprot id: W5MMI6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ano4
gene id: 7918:ano4
uniprot id: W5NDK0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:LOC102686834
gene id: 7918:LOC102686834
uniprot id: W5MFS3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:taf6
gene id: 7918:taf6
uniprot id: W5N9G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

7918:sumf1
gene id: 7918:sumf1
uniprot id: W5MYV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

7918:tmem91
gene id: 7918:tmem91
uniprot id: W5NA57
names: Similarity
messages: Belongs to the CD225/Dispanin family.

7918:LOC102688062
gene id: 7918:LOC102688062
uniprot id: W5MIP3
names: Subcellular Location Annotation
messages: Membrane

7918:LOC107076742
gene id: 7918:LOC107076742
uniprot id: W5NEV3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ramp3
gene id: 7918:ramp3
uniprot id: W5N6X3
names: Similarity
messages: Belongs to the RAMP family.

7918:tulp1
gene id: 7918:tulp1
uniprot id: W5MU22
names: Similarity
messages: Belongs to the TUB family.

7918:LOC102687658
gene id: 7918:LOC102687658
uniprot id: W5MX70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

7918:LOC102698980
gene id: 7918:LOC102698980
uniprot id: W5M0U9
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102696638
gene id: 7918:LOC102696638
uniprot id: W5MZZ1
names: Subcellular Location Annotation
messages: Membrane

7918:sypl1
gene id: 7918:sypl1
uniprot id: W5NFT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

7918:ip6k3
gene id: 7918:ip6k3
uniprot id: W5N4I6
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

7918:nek3
gene id: 7918:nek3
uniprot id: W5MQZ0
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:tacc1
gene id: 7918:tacc1
uniprot id: W5ND72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

7918:folr2
gene id: 7918:folr2
uniprot id: W5MM21
names: Similarity
messages: Belongs to the folate receptor family.

7918:il20
gene id: 7918:il20
uniprot id: W5N385
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

7918:tmem106b
gene id: 7918:tmem106b
uniprot id: W5MZD5
names: Similarity
messages: Belongs to the TMEM106 family.

7918:LOC102694931
gene id: 7918:LOC102694931
uniprot id: W5N2T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

7918:fam73b
gene id: 7918:fam73b
uniprot id: W5M9G0
names: Similarity
messages: Belongs to the mitoguardin family.

7918:ccdc153
gene id: 7918:ccdc153
uniprot id: W5M6C5
names: Similarity
messages: Belongs to the UPF0610 family.

7918:pex14
gene id: 7918:pex14
uniprot id: W5MHQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
messages: Peroxisome membrane

7918:paip2
gene id: 7918:paip2
uniprot id: W5N0P9
names: Similarity
messages: Belongs to the PAIP2 family.

7918:tf
gene id: 7918:tf
uniprot id: W5MU77
names: Similarity
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.

7918:pnoc
gene id: 7918:pnoc
uniprot id: W5NGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

7918:slbp
gene id: 7918:slbp
uniprot id: W5MYS3
names: Similarity
messages: Belongs to the SLBP family.

7918:ctnnb1
gene id: 7918:ctnnb1
uniprot id: W5LZL6
names: Similarity
messages: Belongs to the beta-catenin family.

7918:vcp
gene id: 7918:vcp
uniprot id: W5MHV1
names: Similarity
messages: Belongs to the AAA ATPase family.

7918:mms22l
gene id: 7918:mms22l
uniprot id: W5NKH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

7918:mdh1
gene id: 7918:mdh1
uniprot id: W5NGN6
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

7918:LOC102695655
gene id: 7918:LOC102695655
uniprot id: W5MZJ6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:phkg1
gene id: 7918:phkg1
uniprot id: W5M9H9
names: Subunit
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

7918:stac
gene id: 7918:stac
uniprot id: W5MBH4
names: Subcellular Location Annotation
messages: sarcolemma

7918:rasgrp1
gene id: 7918:rasgrp1
uniprot id: W5N394
names: Similarity
messages: Belongs to the RASGRP family.

7918:LOC102696734
gene id: 7918:LOC102696734
uniprot id: W5NLM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:cdk15
gene id: 7918:cdk15
uniprot id: W5MVZ3
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:LOC102693627
gene id: 7918:LOC102693627
uniprot id: W5MSG2
names: Subcellular Location Annotation
messages: Membrane

7918:tmem144
gene id: 7918:tmem144
uniprot id: W5MNB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

7918:atp5g1
gene id: 7918:atp5g1
uniprot id: W5N7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

7918:pms1
gene id: 7918:pms1
uniprot id: W5MQR1
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

7918:LOC102695582
gene id: 7918:LOC102695582
uniprot id: W5MSP7
names: Subcellular Location Annotation
messages: Nucleus

7918:syt1
gene id: 7918:syt1
uniprot id: W5NHI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: synaptic vesicle membrane

7918:pih1d2
gene id: 7918:pih1d2
uniprot id: W5M037
names: Similarity
messages: Belongs to the PIH1 family.

7918:map3k6
gene id: 7918:map3k6
uniprot id: W5M4W8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

7918:LOC102687755
gene id: 7918:LOC102687755
uniprot id: W5N5D2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: Secreted

7918:LOC102688505
gene id: 7918:LOC102688505
uniprot id: W5N5G1
names: Similarity
messages: Belongs to the intermediate filament family.

7918:LOC102696303
gene id: 7918:LOC102696303
uniprot id: W5NDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

7918:nol10
gene id: 7918:nol10
uniprot id: W5NIX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

7918:abca5
gene id: 7918:abca5
uniprot id: W5N5I4
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102691080
gene id: 7918:LOC102691080
uniprot id: W5NNX8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

7918:mfi2
gene id: 7918:mfi2
uniprot id: W5M009
names: Similarity
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.

7918:LOC102690688
gene id: 7918:LOC102690688
uniprot id: W5M4Q6
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

7918:LOC102690375
gene id: 7918:LOC102690375
uniprot id: W5NGS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:tubgcp5
gene id: 7918:tubgcp5
uniprot id: W5MNF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

7918:hs3st5
gene id: 7918:hs3st5
uniprot id: W5NK24
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

7918:nap1l4
gene id: 7918:nap1l4
uniprot id: W5M0N4
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

7918:cactin
gene id: 7918:cactin
uniprot id: W5MHS3
names: Similarity
messages: Belongs to the CACTIN family.

7918:grin2c
gene id: 7918:grin2c
uniprot id: W5MZ80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

7918:rarb
gene id: 7918:rarb
uniprot id: W5MIX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

7918:dock7
gene id: 7918:dock7
uniprot id: W5MHV0
names: Similarity
messages: Belongs to the DOCK family.

7918:crbn
gene id: 7918:crbn
uniprot id: W5MYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

7918:cops7b
gene id: 7918:cops7b
uniprot id: W5MFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

7918:sema3d
gene id: 7918:sema3d
uniprot id: W5NHZ9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:vax2
gene id: 7918:vax2
uniprot id: W5M0D9
names: Subcellular Location Annotation
messages: Nucleus

7918:tbxas1
gene id: 7918:tbxas1
uniprot id: W5NJU5
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:itgb3
gene id: 7918:itgb3
uniprot id: W5N275
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

7918:b4galt5
gene id: 7918:b4galt5
uniprot id: W5MBD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

7918:LOC102691822
gene id: 7918:LOC102691822
uniprot id: W5N5N9
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

7918:ssr3
gene id: 7918:ssr3
uniprot id: W5M664
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

7918:LOC102698783
gene id: 7918:LOC102698783
uniprot id: W5MAW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

7918:capza2
gene id: 7918:capza2
uniprot id: W5NEY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

7918:LOC102694326
gene id: 7918:LOC102694326
uniprot id: W5MMD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

7918:smpd1
gene id: 7918:smpd1
uniprot id: W5MTI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

7918:fam76b
gene id: 7918:fam76b
uniprot id: W5MLF8
names: Similarity
messages: Belongs to the FAM76 family.

7918:nploc4
gene id: 7918:nploc4
uniprot id: W5N5X1
names: Similarity
messages: Belongs to the NPL4 family.

7918:hdac8
gene id: 7918:hdac8
uniprot id: W5NAX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

7918:mbtd1
gene id: 7918:mbtd1
uniprot id: W5MYT7
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102698835
gene id: 7918:LOC102698835
uniprot id: W5N391
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

7918:tbp
gene id: 7918:tbp
uniprot id: W5NEJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

7918:gbe1
gene id: 7918:gbe1
uniprot id: W5MRC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

7918:parp14
gene id: 7918:parp14
uniprot id: W5M6S1
names: Similarity
messages: Belongs to the ARTD/PARP family.

7918:hoxc11
gene id: 7918:hoxc11
uniprot id: W5MGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

7918:cap1
gene id: 7918:cap1
uniprot id: W5LXQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

7918:oprk1
gene id: 7918:oprk1
uniprot id: W5MF06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:ubald2
gene id: 7918:ubald2
uniprot id: W5MZI3
names: Similarity
messages: Belongs to the UBALD family.

7918:ezh2
gene id: 7918:ezh2
uniprot id: W5N725
names: Subcellular Location Annotation
messages: Nucleus

7918:hoxb9
gene id: 7918:hoxb9
uniprot id: W5N7H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

7918:LOC107075665
gene id: 7918:LOC107075665
uniprot id: W5MYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

7918:fam160a2
gene id: 7918:fam160a2
uniprot id: W5MHN4
names: Similarity
messages: Belongs to the FHIP family.

7918:LOC107075805
gene id: 7918:LOC107075805
uniprot id: W5M281
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

7918:prom1
gene id: 7918:prom1
uniprot id: W5M5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

7918:casp1
gene id: 7918:casp1
uniprot id: W5LZT4
names: Similarity
messages: Belongs to the peptidase C14A family.

7918:LOC102692977
gene id: 7918:LOC102692977
uniprot id: W5M774
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:blmh
gene id: 7918:blmh
uniprot id: W5MI71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

7918:osbpl5
gene id: 7918:osbpl5
uniprot id: W5M0I8
names: Similarity
messages: Belongs to the OSBP family.

7918:dscr3
gene id: 7918:dscr3
uniprot id: W5MC60
names: Similarity
messages: Belongs to the VPS26 family.

7918:zfhx4
gene id: 7918:zfhx4
uniprot id: W5N7K1
names: Subcellular Location Annotation
messages: Nucleus

7918:trmt11
gene id: 7918:trmt11
uniprot id: W5NIE5
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

7918:me2
gene id: 7918:me2
uniprot id: W5N5C8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

7918:tmem199
gene id: 7918:tmem199
uniprot id: W5LXP3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:c8b
gene id: 7918:c8b
uniprot id: W5MQT1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:ppp1r2
gene id: 7918:ppp1r2
uniprot id: W5MBE1
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

7918:LOC102694189
gene id: 7918:LOC102694189
uniprot id: W5MHM6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:slc35e1
gene id: 7918:slc35e1
uniprot id: W5M094
names: Subcellular Location Annotation
messages: Membrane

7918:olfm3
gene id: 7918:olfm3
uniprot id: W5MMX5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Synapse

7918:gabrp
gene id: 7918:gabrp
uniprot id: W5MKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:abcg5
gene id: 7918:abcg5
uniprot id: W5NI14
names: Subcellular Location Annotation
messages: Membrane

7918:trmt44
gene id: 7918:trmt44
uniprot id: W5MW83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

7918:LOC102682983
gene id: 7918:LOC102682983
uniprot id: W5NNM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

7918:rabep1
gene id: 7918:rabep1
uniprot id: W5M342
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

7918:arl5a
gene id: 7918:arl5a
uniprot id: W5M3V9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

7918:LOC102693076
gene id: 7918:LOC102693076
uniprot id: W5MQM3
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

7918:kif23
gene id: 7918:kif23
uniprot id: W5N9F2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:rbm42
gene id: 7918:rbm42
uniprot id: W5M6H6
names: Similarity
messages: Belongs to the RRM RBM42 family.

7918:fam129a
gene id: 7918:fam129a
uniprot id: W5M154
names: Similarity
messages: Belongs to the Niban family.

7918:LOC102696950
gene id: 7918:LOC102696950
uniprot id: W5N8M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:kdm3a
gene id: 7918:kdm3a
uniprot id: W5MY10
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

7918:vkorc1l1
gene id: 7918:vkorc1l1
uniprot id: W5M5D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:haus1
gene id: 7918:haus1
uniprot id: W5MZB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

7918:LOC102694831
gene id: 7918:LOC102694831
uniprot id: W5MSJ0
uniprot id: W5MSK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:LOC102697528
gene id: 7918:LOC102697528
uniprot id: W5NJD8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

7918:stx19
gene id: 7918:stx19
uniprot id: W5NLL3
names: Similarity
messages: Belongs to the syntaxin family.

7918:pik3c2a
gene id: 7918:pik3c2a
uniprot id: W5M537
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

7918:thoc2
gene id: 7918:thoc2
uniprot id: W5NBA6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THOC2 family.
messages: Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with THOC1, POLDIP3 and ZC3H11A.
messages: Nucleus

7918:prkaa2
gene id: 7918:prkaa2
uniprot id: W5MQQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Cytoplasm
messages: Nucleus

7918:wnt2b
gene id: 7918:wnt2b
uniprot id: W5MWA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:LOC102695551
gene id: 7918:LOC102695551
uniprot id: W5N6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

7918:LOC102689800
gene id: 7918:LOC102689800
uniprot id: W5NLR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:psip1
gene id: 7918:psip1
uniprot id: W5N1U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

7918:LOC102692397
gene id: 7918:LOC102692397
uniprot id: W5NNV2
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102692087
gene id: 7918:LOC102692087
uniprot id: W5MXB5
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

7918:tmem63b
gene id: 7918:tmem63b
uniprot id: W5NGG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

7918:LOC102688917
gene id: 7918:LOC102688917
uniprot id: W5NNQ5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:harbi1
gene id: 7918:harbi1
uniprot id: W5MEM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

7918:psmb7
gene id: 7918:psmb7
uniprot id: W5MD30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

7918:eif3e
gene id: 7918:eif3e
uniprot id: W5M5L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm
messages: Nucleus

7918:gnb5
gene id: 7918:gnb5
uniprot id: W5N756
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

7918:LOC102696344
gene id: 7918:LOC102696344
uniprot id: W5MPQ0
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

7918:ap3b1
gene id: 7918:ap3b1
uniprot id: W5MF35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

7918:tspan6
gene id: 7918:tspan6
uniprot id: W5NDV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:matn4
gene id: 7918:matn4
uniprot id: W5MLI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:raf1
gene id: 7918:raf1
uniprot id: W5N9C1
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

7918:szrd1
gene id: 7918:szrd1
uniprot id: W5MMB8
names: Similarity
messages: Belongs to the SZRD1 family.

7918:rrad
gene id: 7918:rrad
uniprot id: W5MC65
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

7918:khdrbs2
gene id: 7918:khdrbs2
uniprot id: W5NK72
names: Similarity
messages: Belongs to the KHDRBS family.

7918:lama2
gene id: 7918:lama2
uniprot id: W5NL66
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

7918:nefm
gene id: 7918:nefm
uniprot id: W5NF84
names: Similarity
messages: Belongs to the intermediate filament family.

7918:usp37
gene id: 7918:usp37
uniprot id: W5MR55
names: Similarity
messages: Belongs to the peptidase C19 family.

7918:zfp36l1
gene id: 7918:zfp36l1
uniprot id: W5N997
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

7918:LOC102690458
gene id: 7918:LOC102690458
uniprot id: W5ML86
names: Cofactor
messages: Divalent metal ions. Mg(2+) is the most effective.

7918:eral1
gene id: 7918:eral1
uniprot id: W5M6A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.

7918:pgpep1
gene id: 7918:pgpep1
uniprot id: W5M1X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

7918:dynlt1
gene id: 7918:dynlt1
uniprot id: W5NHE3
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

7918:plppr3
gene id: 7918:plppr3
uniprot id: W5M0Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

7918:trim63
gene id: 7918:trim63
uniprot id: W5MBB6
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

7918:bcr
gene id: 7918:bcr
uniprot id: W5MJR0
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

7918:fam46b
gene id: 7918:fam46b
uniprot id: W5M7U9
names: Similarity
messages: Belongs to the TENT family.

7918:cct8
gene id: 7918:cct8
uniprot id: W5MRL7
uniprot id: W5MRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

7918:LOC102695604
gene id: 7918:LOC102695604
uniprot id: W5MUK8
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

7918:dao
gene id: 7918:dao
uniprot id: W5MAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

7918:elp5
gene id: 7918:elp5
uniprot id: W5NB21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

7918:zdhhc6
gene id: 7918:zdhhc6
uniprot id: W5N350
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

7918:trpm4
gene id: 7918:trpm4
uniprot id: W5NKS7
names: Subcellular Location Annotation
messages: Membrane

7918:masp2
gene id: 7918:masp2
uniprot id: W5MHL3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:mfsd10
gene id: 7918:mfsd10
uniprot id: W5N0Y8
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102687853
gene id: 7918:LOC102687853
uniprot id: W5MMZ5
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

7918:gpr4
gene id: 7918:gpr4
uniprot id: W5NMG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:podxl2
gene id: 7918:podxl2
uniprot id: W5N7Y4
names: Subcellular Location Annotation
messages: Membrane

7918:mok
gene id: 7918:mok
uniprot id: W5N0F4
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:dnttip1
gene id: 7918:dnttip1
uniprot id: W5MID3
names: Subcellular Location Annotation
messages: Nucleus

7918:fam124b
gene id: 7918:fam124b
uniprot id: W5M8P2
names: Similarity
messages: Belongs to the FAM124 family.

7918:LOC102688971
gene id: 7918:LOC102688971
uniprot id: W5N2Z8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

7918:opn1sw
gene id: 7918:opn1sw
uniprot id: W5NET8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

7918:kcnb2
gene id: 7918:kcnb2
uniprot id: W5M847
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: dendrite

7918:LOC102687197
gene id: 7918:LOC102687197
uniprot id: W5NDZ5
names: Similarity
messages: Belongs to the intermediate filament family.

7918:srxn1
gene id: 7918:srxn1
uniprot id: W5M2J1
names: Similarity
messages: Belongs to the sulfiredoxin family.

7918:LOC102691443
gene id: 7918:LOC102691443
uniprot id: W5LVD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

7918:LOC102682152
gene id: 7918:LOC102682152
uniprot id: W5N4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

7918:impact
gene id: 7918:impact
uniprot id: W5MHA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

7918:kcng2
gene id: 7918:kcng2
uniprot id: W5MPG7
names: Subcellular Location Annotation
messages: Membrane

7918:ada
gene id: 7918:ada
uniprot id: W5M1D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

7918:hoxb3
gene id: 7918:hoxb3
uniprot id: W5N7F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

7918:mrpl35
gene id: 7918:mrpl35
uniprot id: W5MY38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

7918:slc5a6
gene id: 7918:slc5a6
uniprot id: W5NG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

7918:pgap2
gene id: 7918:pgap2
uniprot id: W5MMX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

7918:zufsp
gene id: 7918:zufsp
uniprot id: W5NKK2
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

7918:znrf3
gene id: 7918:znrf3
uniprot id: W5M5P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

7918:xkr7
gene id: 7918:xkr7
uniprot id: W5MDS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

7918:slc39a9
gene id: 7918:slc39a9
uniprot id: W5NA31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

7918:lamp5
gene id: 7918:lamp5
uniprot id: W5NI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Membrane

7918:esr2
gene id: 7918:esr2
uniprot id: W5MW66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

7918:c7
gene id: 7918:c7
uniprot id: W5MMS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:LOC102698599
gene id: 7918:LOC102698599
uniprot id: W5NIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

7918:LOC102697629
gene id: 7918:LOC102697629
uniprot id: W5N774
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

7918:chrna5
gene id: 7918:chrna5
uniprot id: W5NAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:zyg11b
gene id: 7918:zyg11b
uniprot id: W5MX18
names: Similarity
messages: Belongs to the zyg-11 family.

7918:gls
gene id: 7918:gls
uniprot id: W5MUW9
names: Similarity
messages: Belongs to the glutaminase family.

7918:pex13
gene id: 7918:pex13
uniprot id: W5NGV5
names: Similarity
messages: Belongs to the peroxin-13 family.

7918:mdga2
gene id: 7918:mdga2
uniprot id: W5N025
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:LOC102691397
gene id: 7918:LOC102691397
uniprot id: W5MTJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

7918:xkr9
gene id: 7918:xkr9
uniprot id: W5M8Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

7918:rps7
gene id: 7918:rps7
uniprot id: W5NKX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

7918:grm3
gene id: 7918:grm3
uniprot id: W5NJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

7918:KEF94 p10
gene id: 7918:KEF94_p10
uniprot id: Q8HQN0
uniprot id: W5NPB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

7918:meox1
gene id: 7918:meox1
uniprot id: W5N2R0
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102698363
gene id: 7918:LOC102698363
uniprot id: W5MN58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

7918:LOC102687325
gene id: 7918:LOC102687325
uniprot id: W5NGI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

7918:LOC102683109
gene id: 7918:LOC102683109
uniprot id: W5N4C8
names: Similarity
messages: Belongs to the dpy-30 family.

7918:traf3
gene id: 7918:traf3
uniprot id: W5MUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

7918:ufc1
gene id: 7918:ufc1
uniprot id: W5M1L5
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

7918:sox4
gene id: 7918:sox4
uniprot id: W5NP80
names: Subcellular Location Annotation
messages: Nucleus

7918:rsph3
gene id: 7918:rsph3
uniprot id: W5NHV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flagellar radial spoke RSP3 family.
messages: flagellum axoneme

7918:aup1
gene id: 7918:aup1
uniprot id: W5M1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AUP1 family.
messages: Membrane

7918:zdhhc8
gene id: 7918:zdhhc8
uniprot id: W5M3T4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

7918:pcyox1l
gene id: 7918:pcyox1l
uniprot id: W5MS66
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

7918:pde2a
gene id: 7918:pde2a
uniprot id: W5MLN1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:rgn
gene id: 7918:rgn
uniprot id: W5MN57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

7918:sox3
gene id: 7918:sox3
uniprot id: W5NLT9
names: Subcellular Location Annotation
messages: Nucleus

7918:fbxo34
gene id: 7918:fbxo34
uniprot id: W5N1E6
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

7918:avpi1
gene id: 7918:avpi1
uniprot id: W5M7S4
names: Function
messages: May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.

7918:ndufb6
gene id: 7918:ndufb6
uniprot id: W5N7D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

7918:irx4
gene id: 7918:irx4
uniprot id: W5MQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

7918:txnl4a
gene id: 7918:txnl4a
uniprot id: W5MPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

7918:LOC102685645
gene id: 7918:LOC102685645
uniprot id: W5NA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

7918:fam102b
gene id: 7918:fam102b
uniprot id: W5MMI1
names: Similarity
messages: Belongs to the EEIG family.

7918:cacng1
gene id: 7918:cacng1
uniprot id: W5N843
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

7918:ssbp2
gene id: 7918:ssbp2
uniprot id: W5M207
names: Subcellular Location Annotation
messages: Nucleus

7918:rnf157
gene id: 7918:rnf157
uniprot id: W5MZH5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

7918:tpp2
gene id: 7918:tpp2
uniprot id: W5MV60
uniprot id: W5MV65
names: Similarity
messages: Belongs to the peptidase S8 family.

7918:wars
gene id: 7918:wars
uniprot id: W5N0U5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

7918:usp44
gene id: 7918:usp44
uniprot id: W5NFH5
names: Similarity
messages: Belongs to the peptidase C19 family.

7918:reep2
gene id: 7918:reep2
uniprot id: W5MTD5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:LOC102691553
gene id: 7918:LOC102691553
uniprot id: W5MNF0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:slc35f6
gene id: 7918:slc35f6
uniprot id: W5NHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

7918:LOC102691741
gene id: 7918:LOC102691741
uniprot id: W5N4A4
names: Similarity
messages: Belongs to the DDIT4 family.

7918:cnksr2
gene id: 7918:cnksr2
uniprot id: W5M7N5
names: Similarity
messages: Belongs to the CNKSR family.

7918:clns1a
gene id: 7918:clns1a
uniprot id: W5MHL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

7918:elovl7
gene id: 7918:elovl7
uniprot id: W5MLX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:LOC102691496
gene id: 7918:LOC102691496
uniprot id: M1ZML6
uniprot id: W5MWY5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.
messages: Peroxisome

7918:marcks
gene id: 7918:marcks
uniprot id: W5NK27
names: Similarity
messages: Belongs to the MARCKS family.

7918:tmem200a
gene id: 7918:tmem200a
uniprot id: W5NMX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

7918:lancl2
gene id: 7918:lancl2
uniprot id: W5MXI2
names: Similarity
messages: Belongs to the LanC-like protein family.

7918:il17rd
gene id: 7918:il17rd
uniprot id: W5N713
names: Subcellular Location Annotation
messages: Membrane

7918:nog
gene id: 7918:nog
uniprot id: W5NMJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

7918:pnmt
gene id: 7918:pnmt
uniprot id: W5N4U7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

7918:LOC102698806
gene id: 7918:LOC102698806
uniprot id: W5LYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

7918:cpm
gene id: 7918:cpm
uniprot id: W5NH45
names: Similarity
messages: Belongs to the peptidase M14 family.

7918:stk38
gene id: 7918:stk38
uniprot id: W5N0J8
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:med17
gene id: 7918:med17
uniprot id: W5MKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

7918:cstf1
gene id: 7918:cstf1
uniprot id: W5M6N5
names: Subcellular Location Annotation
messages: Nucleus

7918:tmem135
gene id: 7918:tmem135
uniprot id: W5MJQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane

7918:thoc7
gene id: 7918:thoc7
uniprot id: W5MWC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

7918:pdhx
gene id: 7918:pdhx
uniprot id: W5LZJ0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

7918:LOC102693964
gene id: 7918:LOC102693964
uniprot id: W5MMA8
names: Similarity
messages: Belongs to the globin family.

7918:cpeb1
gene id: 7918:cpeb1
uniprot id: W5NCW8
names: Similarity
messages: Belongs to the RRM CPEB family.

7918:pus1
gene id: 7918:pus1
uniprot id: W5MG95
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

7918:otop2
gene id: 7918:otop2
uniprot id: W5N686
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

7918:tm4sf5
gene id: 7918:tm4sf5
uniprot id: W5N9V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

7918:tex261
gene id: 7918:tex261
uniprot id: W5M0I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

7918:LOC102696963
gene id: 7918:LOC102696963
uniprot id: W5N1N6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

7918:pdss1
gene id: 7918:pdss1
uniprot id: W5MLK8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

7918:sept10
gene id: 7918:sept10
uniprot id: W5MW39
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

7918:LOC102683382
gene id: 7918:LOC102683382
uniprot id: W5NME2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

7918:nup205
gene id: 7918:nup205
uniprot id: W5NIQ6
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

7918:LOC102694050
gene id: 7918:LOC102694050
uniprot id: W5M844
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

7918:LOC107079849
gene id: 7918:LOC107079849
uniprot id: W5M3I3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:acaa2
gene id: 7918:acaa2
uniprot id: W5MZS1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

7918:pde6h
gene id: 7918:pde6h
uniprot id: W5N2L2
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

7918:clg21h9orf116
gene id: 7918:clg21h9orf116
uniprot id: W5M7R1
names: Subcellular Location Annotation
messages: cilium axoneme

7918:tfec
gene id: 7918:tfec
uniprot id: W5NG68
uniprot id: W5NG70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

7918:rin2
gene id: 7918:rin2
uniprot id: W5NH09
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

7918:inpp4a
gene id: 7918:inpp4a
uniprot id: W5MQ60
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

7918:lpin1
gene id: 7918:lpin1
uniprot id: W5NIZ0
names: Similarity
messages: Belongs to the lipin family.

7918:dusp27
gene id: 7918:dusp27
uniprot id: W5MTY1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

7918:srp68
gene id: 7918:srp68
uniprot id: W5N7R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

7918:LOC102683880
gene id: 7918:LOC102683880
uniprot id: W5MUM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

7918:pptc7
gene id: 7918:pptc7
uniprot id: W5MKF9
names: Similarity
messages: Belongs to the PP2C family.

7918:dock4
gene id: 7918:dock4
uniprot id: W5NG48
names: Similarity
messages: Belongs to the DOCK family.

7918:gpr20
gene id: 7918:gpr20
uniprot id: W5NP76
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:LOC102691183
gene id: 7918:LOC102691183
uniprot id: W5NIT5
names: Subcellular Location Annotation
messages: Membrane

7918:snx5
gene id: 7918:snx5
uniprot id: W5NFA5
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

7918:gpc2
gene id: 7918:gpc2
uniprot id: W5N6B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

7918:tsc22d3
gene id: 7918:tsc22d3
uniprot id: W5N948
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

7918:serpine3
gene id: 7918:serpine3
uniprot id: W5MW74
names: Similarity
messages: Belongs to the serpin family.

7918:rab27a
gene id: 7918:rab27a
uniprot id: W5N7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

7918:fgf3
gene id: 7918:fgf3
uniprot id: W5MCR1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

7918:LOC102684400
gene id: 7918:LOC102684400
uniprot id: W5N7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

7918:pkig
gene id: 7918:pkig
uniprot id: W5M1E7
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

7918:nlgn1
gene id: 7918:nlgn1
uniprot id: W5LYB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

7918:LOC102698174
gene id: 7918:LOC102698174
uniprot id: W5MGT6
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:LOC102690342
gene id: 7918:LOC102690342
uniprot id: W5MZT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:atxn7l3
gene id: 7918:atxn7l3
uniprot id: W5N2G3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of some SAGA transcription coactivator-HAT complexes. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain forms part of the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

7918:coro2b
gene id: 7918:coro2b
uniprot id: W5N9B0
names: Similarity
messages: Belongs to the WD repeat coronin family.

7918:neto1
gene id: 7918:neto1
uniprot id: W5N837
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102698220
gene id: 7918:LOC102698220
uniprot id: W5N346
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

7918:mcoln3
gene id: 7918:mcoln3
uniprot id: W5ME37
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

7918:LOC102692624
gene id: 7918:LOC102692624
uniprot id: W5N7E3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:ca6
gene id: 7918:ca6
uniprot id: W5MJU1
names: Caution
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversible hydration of carbon dioxide.

7918:foxo3
gene id: 7918:foxo3
uniprot id: W5NIQ0
names: Subcellular Location Annotation
messages: Nucleus

7918:ndfip2
gene id: 7918:ndfip2
uniprot id: W5MAM2
names: Subcellular Location Annotation
messages: Membrane

7918:s100z
gene id: 7918:s100z
uniprot id: W5MEL8
names: Similarity
messages: Belongs to the S-100 family.

7918:LOC102684260
gene id: 7918:LOC102684260
uniprot id: W5NNX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:clg23h16orf87
gene id: 7918:clg23h16orf87
uniprot id: W5MDX2
names: Similarity
messages: Belongs to the UPF0547 family.

7918:tctex1d2
gene id: 7918:tctex1d2
uniprot id: W5MPX0
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

7918:hspa4
gene id: 7918:hspa4
uniprot id: W5MX67
names: Similarity
messages: Belongs to the heat shock protein 70 family.

7918:pde6b
gene id: 7918:pde6b
uniprot id: W5N355
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:LOC102696601
gene id: 7918:LOC102696601
uniprot id: W5MIV4
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

7918:tyr
gene id: 7918:tyr
uniprot id: W5MJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

7918:rab3a
gene id: 7918:rab3a
uniprot id: W5M1K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

7918:dpcd
gene id: 7918:dpcd
uniprot id: W5N166
names: Similarity
messages: Belongs to the DPCD family.

7918:galnt8
gene id: 7918:galnt8
uniprot id: W5NIW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:yme1l1
gene id: 7918:yme1l1
uniprot id: W5MLA2
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

7918:LOC102688038
gene id: 7918:LOC102688038
uniprot id: W5NP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

7918:mnx1
gene id: 7918:mnx1
uniprot id: W5N3W1
names: Subcellular Location Annotation
messages: Nucleus

7918:cutc
gene id: 7918:cutc
uniprot id: W5N504
names: Similarity
messages: Belongs to the CutC family.

7918:pdcd5
gene id: 7918:pdcd5
uniprot id: W5M0J1
names: Similarity
messages: Belongs to the PDCD5 family.

7918:adam11
gene id: 7918:adam11
uniprot id: W5N0I0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:rhot1
gene id: 7918:rhot1
uniprot id: W5N8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

7918:LOC107077373
gene id: 7918:LOC107077373
uniprot id: W5MV63
names: Similarity
messages: Belongs to the MDFI family.

7918:bet1l
gene id: 7918:bet1l
uniprot id: W5M345
names: Subcellular Location Annotation
messages: Membrane

7918:fktn
gene id: 7918:fktn
uniprot id: W5M5J1
names: Similarity
messages: Belongs to the LicD transferase family.

7918:LOC102683960
gene id: 7918:LOC102683960
uniprot id: W5MII2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:nde1
gene id: 7918:nde1
uniprot id: W5MK97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

7918:ung
gene id: 7918:ung
uniprot id: W5MAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

7918:b3gnt3
gene id: 7918:b3gnt3
uniprot id: W5M468
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:LOC102698046
gene id: 7918:LOC102698046
uniprot id: W5MIZ3
names: Similarity
messages: Belongs to the TPPP family.

7918:myeov2
gene id: 7918:myeov2
uniprot id: W5MJJ0
names: Similarity
messages: Belongs to the CSN9 family.

7918:ing3
gene id: 7918:ing3
uniprot id: W5NFN2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

7918:cldn8
gene id: 7918:cldn8
uniprot id: W5NNE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:scube2
gene id: 7918:scube2
uniprot id: W5M706
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:tm6sf2
gene id: 7918:tm6sf2
uniprot id: W5MB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

7918:LOC102689055
gene id: 7918:LOC102689055
uniprot id: W5MCB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

7918:nudc
gene id: 7918:nudc
uniprot id: W5M8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

7918:podxl
gene id: 7918:podxl
uniprot id: W5NF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the podocalyxin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: filopodium
messages: lamellipodium
messages: microvillus
messages: ruffle

7918:eif2b1
gene id: 7918:eif2b1
uniprot id: W5MF99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

7918:pdk3
gene id: 7918:pdk3
uniprot id: W5M115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

7918:traf2
gene id: 7918:traf2
uniprot id: W5LXT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

7918:LOC102689665
gene id: 7918:LOC102689665
uniprot id: W5MJ90
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:arpp19
gene id: 7918:arpp19
uniprot id: W5N7B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

7918:nipal1
gene id: 7918:nipal1
uniprot id: W5N279
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

7918:glis3
gene id: 7918:glis3
uniprot id: W5N5R6
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

7918:ctbp2
gene id: 7918:ctbp2
uniprot id: W5MMR5
uniprot id: W5MMT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

7918:ms4a12
gene id: 7918:ms4a12
uniprot id: W5MNH9
names: Similarity
messages: Belongs to the MS4A family.

7918:strn
gene id: 7918:strn
uniprot id: W5NG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

7918:snx8
gene id: 7918:snx8
uniprot id: W5LZX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

7918:nsun7
gene id: 7918:nsun7
uniprot id: W5N5Q3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102687628
gene id: 7918:LOC102687628
uniprot id: W5MKP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

7918:foxf2
gene id: 7918:foxf2
uniprot id: W5N5T3
names: Subcellular Location Annotation
messages: Nucleus

7918:hapln4
gene id: 7918:hapln4
uniprot id: W5MB73
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:clcn5
gene id: 7918:clcn5
uniprot id: W5NAI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:LOC102682342
gene id: 7918:LOC102682342
uniprot id: W5NM36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

7918:pop7
gene id: 7918:pop7
uniprot id: W5NLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like Alba family.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: nucleolus

7918:ndufa7
gene id: 7918:ndufa7
uniprot id: W5M424
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

7918:akap9
gene id: 7918:akap9
uniprot id: W5MX58
names: Subcellular Location Annotation
messages: centrosome

7918:npy1r
gene id: 7918:npy1r
uniprot id: W5MMQ5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:ctsh
gene id: 7918:ctsh
uniprot id: W5NAF9
names: Similarity
messages: Belongs to the peptidase C1 family.

7918:ildr1
gene id: 7918:ildr1
uniprot id: W5MTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

7918:snrpg
gene id: 7918:snrpg
uniprot id: W5NF71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

7918:LOC102695878
gene id: 7918:LOC102695878
uniprot id: W5MAS1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:LOC102696192
gene id: 7918:LOC102696192
uniprot id: W5MPV8
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

7918:meox2
gene id: 7918:meox2
uniprot id: W5MZP5
names: Subcellular Location Annotation
messages: Nucleus

7918:tm9sf4
gene id: 7918:tm9sf4
uniprot id: W5MFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

7918:atp6v0e1
gene id: 7918:atp6v0e1
uniprot id: W5MS38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

7918:LOC102687267
gene id: 7918:LOC102687267
uniprot id: W5MVI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

7918:LOC102699044
gene id: 7918:LOC102699044
uniprot id: W5M0P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

7918:lgals3bp
gene id: 7918:lgals3bp
uniprot id: W5N4R9
names: Subcellular Location Annotation
messages: extracellular matrix

7918:atp6v0a4
gene id: 7918:atp6v0a4
uniprot id: W5NJW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

7918:tmcc2
gene id: 7918:tmcc2
uniprot id: W5N4Q9
names: Similarity
messages: Belongs to the TEX28 family.

7918:rax
gene id: 7918:rax
uniprot id: W5N1Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus
messages: Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.

7918:rpf1
gene id: 7918:rpf1
uniprot id: W5MV94
names: Subcellular Location Annotation
messages: nucleolus

7918:cdh8
gene id: 7918:cdh8
uniprot id: W5MD66
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

7918:xkr4
gene id: 7918:xkr4
uniprot id: W5ME82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

7918:crh
gene id: 7918:crh
uniprot id: W5NMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

7918:egf
gene id: 7918:egf
uniprot id: W5N1G8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:tmem237
gene id: 7918:tmem237
uniprot id: W5MW63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

7918:irx3
gene id: 7918:irx3
uniprot id: W5MJR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

7918:xpnpep2
gene id: 7918:xpnpep2
uniprot id: W5NDU1
names: Similarity
messages: Belongs to the peptidase M24B family.

7918:cdk20
gene id: 7918:cdk20
uniprot id: W5NC09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: cilium

7918:LOC102698824
gene id: 7918:LOC102698824
uniprot id: W5NAH6
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:actr2
gene id: 7918:actr2
uniprot id: W5NGJ0
uniprot id: W5NGJ1
names: Similarity
messages: Belongs to the actin family.

7918:adcy9
gene id: 7918:adcy9
uniprot id: W5M448
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

7918:asf1b
gene id: 7918:asf1b
uniprot id: W5MV14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

7918:kcnd2
gene id: 7918:kcnd2
uniprot id: W5NFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

7918:aurkaip1
gene id: 7918:aurkaip1
uniprot id: W5M501
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

7918:oxct1
gene id: 7918:oxct1
uniprot id: W5MMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

7918:man2a1
gene id: 7918:man2a1
uniprot id: W5MWN5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

7918:slc27a1
gene id: 7918:slc27a1
uniprot id: W5MPY4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

7918:phka2
gene id: 7918:phka2
uniprot id: W5ML17
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

7918:cdkl1
gene id: 7918:cdkl1
uniprot id: W5N1S5
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:LOC102686012
gene id: 7918:LOC102686012
uniprot id: W5NIY3
names: Subcellular Location Annotation
messages: Membrane

7918:pgm1
gene id: 7918:pgm1
uniprot id: W5MI76
names: Similarity
messages: Belongs to the phosphohexose mutase family.

7918:st18
gene id: 7918:st18
uniprot id: W5MFD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

7918:b3galt6
gene id: 7918:b3galt6
uniprot id: W5NNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:cpz
gene id: 7918:cpz
uniprot id: W5MWB3
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102688351
gene id: 7918:LOC102688351
uniprot id: W5NCB2
names: Subcellular Location Annotation
messages: Nucleus

7918:sde2
gene id: 7918:sde2
uniprot id: W5NF39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Cytoplasm
messages: Nucleus

7918:ngf
gene id: 7918:ngf
uniprot id: W5NN17
names: Similarity
messages: Belongs to the NGF-beta family.

7918:mogat1
gene id: 7918:mogat1
uniprot id: W5M964
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:rab4a
gene id: 7918:rab4a
uniprot id: W5NEI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

7918:dbndd1
gene id: 7918:dbndd1
uniprot id: W5LYQ1
names: Similarity
messages: Belongs to the dysbindin family.

7918:LOC102696592
gene id: 7918:LOC102696592
uniprot id: W5MLV7
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

7918:ucma
gene id: 7918:ucma
uniprot id: W5NFE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

7918:b3galt1
gene id: 7918:b3galt1
uniprot id: W5NMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

7918:slc24a5
gene id: 7918:slc24a5
uniprot id: W5N6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

7918:sec24c
gene id: 7918:sec24c
uniprot id: W5N4A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

7918:ppp1r21
gene id: 7918:ppp1r21
uniprot id: W5NHJ4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

7918:mysm1
gene id: 7918:mysm1
uniprot id: W5MR04
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

7918:sec22b
gene id: 7918:sec22b
uniprot id: W5MVY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

7918:fbln7
gene id: 7918:fbln7
uniprot id: W5NIH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:ntmt1
gene id: 7918:ntmt1
uniprot id: W5M2J9
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

7918:tmem120a
gene id: 7918:tmem120a
uniprot id: W5M0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

7918:vps45
gene id: 7918:vps45
uniprot id: W5MPV5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

7918:polr1b
gene id: 7918:polr1b
uniprot id: W5NIJ4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

7918:amn
gene id: 7918:amn
uniprot id: W5MUG7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:prok1
gene id: 7918:prok1
uniprot id: W5N194
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

7918:fermt1
gene id: 7918:fermt1
uniprot id: W5NI53
names: Similarity
messages: Belongs to the kindlin family.

7918:egr2
gene id: 7918:egr2
uniprot id: W5MIS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

7918:LOC102695284
gene id: 7918:LOC102695284
uniprot id: W5MT15
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

7918:calhm3
gene id: 7918:calhm3
uniprot id: W5N1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

7918:mkx
gene id: 7918:mkx
uniprot id: W5ML14
names: Subcellular Location Annotation
messages: Nucleus

7918:KEF94 p05
gene id: 7918:KEF94_p05
uniprot id: Q8HQM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

7918:b4galt4
gene id: 7918:b4galt4
uniprot id: W5M4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

7918:trim62
gene id: 7918:trim62
uniprot id: W5LYW3
names: Subcellular Location Annotation
messages: Cytoplasm

7918:ctsd
gene id: 7918:ctsd
uniprot id: W5M2U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

7918:odf2l
gene id: 7918:odf2l
uniprot id: W5MDA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

7918:thbs4
gene id: 7918:thbs4
uniprot id: W5MFY7
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:prkacb
gene id: 7918:prkacb
uniprot id: W5MP60
uniprot id: W5MP72
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

7918:LOC102687130
gene id: 7918:LOC102687130
uniprot id: W5NC72
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PTBP2; the interaction is direct.
messages: Nucleus

7918:iqcd
gene id: 7918:iqcd
uniprot id: W5MPJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC10 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
messages: flagellum axoneme

7918:twistnb
gene id: 7918:twistnb
uniprot id: W5N055
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

7918:sema6c
gene id: 7918:sema6c
uniprot id: W5MLZ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:rps21
gene id: 7918:rps21
uniprot id: W5MDY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

7918:lzts2
gene id: 7918:lzts2
uniprot id: W5N4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

7918:tspan12
gene id: 7918:tspan12
uniprot id: W5NFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:ak5
gene id: 7918:ak5
uniprot id: W5M7G3
names: Similarity
messages: Belongs to the adenylate kinase family.

7918:rrp8
gene id: 7918:rrp8
uniprot id: W5MTK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Probable methyltransferase required to silence rDNA.
messages: nucleolus

7918:dpm3
gene id: 7918:dpm3
uniprot id: W5NMC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

7918:fat1
gene id: 7918:fat1
uniprot id: W5N8Y9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:pde3b
gene id: 7918:pde3b
uniprot id: W5M5R4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:per1
gene id: 7918:per1
uniprot id: W5N754
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:col4a6
gene id: 7918:col4a6
uniprot id: W5NAM9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

7918:clta
gene id: 7918:clta
uniprot id: W5MZ97
uniprot id: W5MZA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

7918:csk
gene id: 7918:csk
uniprot id: W5NBI7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:copb2
gene id: 7918:copb2
uniprot id: W5MA32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

7918:hoxc13
gene id: 7918:hoxc13
uniprot id: W5MGU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

7918:ints12
gene id: 7918:ints12
uniprot id: W5N4H8
names: Similarity
messages: Belongs to the Integrator subunit 12 family.

7918:LOC102689192
gene id: 7918:LOC102689192
uniprot id: W5NN11
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102695738
gene id: 7918:LOC102695738
uniprot id: W5MH63
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

7918:trip13
gene id: 7918:trip13
uniprot id: W5MNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

7918:nmb
gene id: 7918:nmb
uniprot id: W5NBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

7918:gpr161
gene id: 7918:gpr161
uniprot id: W5MQ15
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:map2k1
gene id: 7918:map2k1
uniprot id: W5N8Y7
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:tti2
gene id: 7918:tti2
uniprot id: W5NDB6
names: Similarity
messages: Belongs to the TTI2 family.

7918:orc1
gene id: 7918:orc1
uniprot id: W5MGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

7918:rad50
gene id: 7918:rad50
uniprot id: W5MWI4
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

7918:cds1
gene id: 7918:cds1
uniprot id: W5MJL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

7918:rhpn1
gene id: 7918:rhpn1
uniprot id: W5MQ06
names: Similarity
messages: Belongs to the RHPN family.

7918:LOC102694723
gene id: 7918:LOC102694723
uniprot id: W5NH73
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

7918:LOC102685261
gene id: 7918:LOC102685261
uniprot id: W5MJF0
names: Subcellular Location Annotation
messages: Nucleus

7918:gucy1b3
gene id: 7918:gucy1b3
uniprot id: W5MNT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

7918:nmt2
gene id: 7918:nmt2
uniprot id: W5MWM4
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

7918:haao
gene id: 7918:haao
uniprot id: W5NI59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

7918:oplah
gene id: 7918:oplah
uniprot id: W5MQX0
names: Similarity
messages: Belongs to the oxoprolinase family.

7918:LOC102682306
gene id: 7918:LOC102682306
uniprot id: W5N134
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

7918:sppl2a
gene id: 7918:sppl2a
uniprot id: W5N647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

7918:slc19a2
gene id: 7918:slc19a2
uniprot id: W5M0K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

7918:tmem35
gene id: 7918:tmem35
uniprot id: W5NDX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

7918:LOC102686740
gene id: 7918:LOC102686740
uniprot id: W5N7G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

7918:slc35b4
gene id: 7918:slc35b4
uniprot id: W5NF28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

7918:fgf13
gene id: 7918:fgf13
uniprot id: W5NDE4
uniprot id: W5NDE6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

7918:pou4f1
gene id: 7918:pou4f1
uniprot id: W5MAW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

7918:rpe65
gene id: 7918:rpe65
uniprot id: W5MTE8
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

7918:LOC102695089
gene id: 7918:LOC102695089
uniprot id: W5MXH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

7918:LOC102692420
gene id: 7918:LOC102692420
uniprot id: W5N7D7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:uba3
gene id: 7918:uba3
uniprot id: W5MVG5
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

7918:hesx1
gene id: 7918:hesx1
uniprot id: W5N702
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

7918:LOC102698678
gene id: 7918:LOC102698678
uniprot id: W5N477
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:cldn10
gene id: 7918:cldn10
uniprot id: W5MC97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

7918:rbpj
gene id: 7918:rbpj
uniprot id: W5MU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

7918:svep1
gene id: 7918:svep1
uniprot id: W5N783
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:med6
gene id: 7918:med6
uniprot id: W5N9J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

7918:eif4a2
gene id: 7918:eif4a2
uniprot id: W5LXU4
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

7918:LOC102688110
gene id: 7918:LOC102688110
uniprot id: W5MXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

7918:itk
gene id: 7918:itk
uniprot id: W5MUG5
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:smc5
gene id: 7918:smc5
uniprot id: W5MT96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

7918:psmc3ip
gene id: 7918:psmc3ip
uniprot id: W5N3W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

7918:LOC102682207
gene id: 7918:LOC102682207
uniprot id: W5LYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

7918:dtd2
gene id: 7918:dtd2
uniprot id: W5MTH7
names: Similarity
messages: Belongs to the DTD family.

7918:nfib
gene id: 7918:nfib
uniprot id: W5MZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

7918:hlx
gene id: 7918:hlx
uniprot id: W5NHY6
names: Subcellular Location Annotation
messages: Nucleus

7918:pcyox1
gene id: 7918:pcyox1
uniprot id: W5NF69
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

7918:mboat7
gene id: 7918:mboat7
uniprot id: W5MMU9
names: Subcellular Location Annotation
messages: Membrane

7918:KEF94 p13
gene id: 7918:KEF94_p13
uniprot id: Q8HQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

7918:LOC102688367
gene id: 7918:LOC102688367
uniprot id: W5MLZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

7918:adamts14
gene id: 7918:adamts14
uniprot id: W5MCG7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:tmem65
gene id: 7918:tmem65
uniprot id: W5MRE8
names: Subcellular Location Annotation
messages: Membrane

7918:lmbr1
gene id: 7918:lmbr1
uniprot id: W5N3Z3
names: Similarity
messages: Belongs to the LIMR family.

7918:notum
gene id: 7918:notum
uniprot id: W5N4E5
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

7918:gls2
gene id: 7918:gls2
uniprot id: W5MBZ8
names: Similarity
messages: Belongs to the glutaminase family.

7918:LOC102694411
gene id: 7918:LOC102694411
uniprot id: W5NP41
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

7918:wdr12
gene id: 7918:wdr12
uniprot id: W5MVU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

7918:eif4e
gene id: 7918:eif4e
uniprot id: W5N2Z6
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

7918:steap2
gene id: 7918:steap2
uniprot id: W5MWP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

7918:LOC102682951
gene id: 7918:LOC102682951
uniprot id: W5LXY2
names: Similarity
messages: Belongs to the CDI family.

7918:LOC102685476
gene id: 7918:LOC102685476
uniprot id: W5ME01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

7918:spic
gene id: 7918:spic
uniprot id: W5NDI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

7918:eri1
gene id: 7918:eri1
uniprot id: W5N2U9
names: Subcellular Location Annotation
messages: Cytoplasm

7918:fancm
gene id: 7918:fancm
uniprot id: W5MZV3
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.

7918:fasn
gene id: 7918:fasn
uniprot id: W5N3H3
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

7918:foxg1
gene id: 7918:foxg1
uniprot id: W5NME8
names: Subcellular Location Annotation
messages: Nucleus

7918:nans
gene id: 7918:nans
uniprot id: W5MZB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-III AFP family.
messages: Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth.
messages: Secreted

7918:puf60
gene id: 7918:puf60
uniprot id: W5MVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

7918:bloc1s5
gene id: 7918:bloc1s5
uniprot id: W5N6N0
names: Function
names: Similarity
messages: Belongs to the BLOC1S5 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).

7918:hbegf
gene id: 7918:hbegf
uniprot id: W5N464
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:LOC102687447
gene id: 7918:LOC102687447
uniprot id: W5N1Y0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

7918:kcnf1
gene id: 7918:kcnf1
uniprot id: W5NN96
names: Subcellular Location Annotation
messages: Membrane

7918:map1lc3b
gene id: 7918:map1lc3b
uniprot id: W5M703
names: Similarity
messages: Belongs to the ATG8 family.

7918:fam110d
gene id: 7918:fam110d
uniprot id: W5NMA8
names: Similarity
messages: Belongs to the FAM110 family.

7918:LOC102692092
gene id: 7918:LOC102692092
uniprot id: W5M4K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways.

7918:kri1
gene id: 7918:kri1
uniprot id: W5MM09
names: Similarity
messages: Belongs to the KRI1 family.

7918:LOC102693669
gene id: 7918:LOC102693669
uniprot id: W5NL00
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102690992
gene id: 7918:LOC102690992
uniprot id: W5NMH3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:lama5
gene id: 7918:lama5
uniprot id: W5ME48
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

7918:cd200r1
gene id: 7918:cd200r1
uniprot id: W5MAJ5
names: Similarity
messages: Belongs to the CD200R family.

7918:snap25
gene id: 7918:snap25
uniprot id: W5NG65
uniprot id: W5NG67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

7918:lin7a
gene id: 7918:lin7a
uniprot id: W5NHL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

7918:LOC102683983
gene id: 7918:LOC102683983
uniprot id: W5MH28
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

7918:efnb1
gene id: 7918:efnb1
uniprot id: W5NBU6
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:med18
gene id: 7918:med18
uniprot id: W5M5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

7918:ndufb3
gene id: 7918:ndufb3
uniprot id: W5MUI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

7918:pde5a
gene id: 7918:pde5a
uniprot id: W5N6D2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:unc13c
gene id: 7918:unc13c
uniprot id: W5N7G4
names: Subcellular Location Annotation
messages: Cytoplasm

7918:enkd1
gene id: 7918:enkd1
uniprot id: W5NF17
names: Subcellular Location Annotation
messages: cilium axoneme

7918:faim2
gene id: 7918:faim2
uniprot id: W5MGI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

7918:LOC102684512
gene id: 7918:LOC102684512
uniprot id: W5MQA7
names: Subcellular Location Annotation
messages: Membrane

7918:LOC107078362
gene id: 7918:LOC107078362
uniprot id: W5MAA6
names: Subcellular Location Annotation
messages: Nucleus

7918:themis
gene id: 7918:themis
uniprot id: W5NL72
names: Similarity
messages: Belongs to the themis family.

7918:lgr5
gene id: 7918:lgr5
uniprot id: W5NHA9
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102689614
gene id: 7918:LOC102689614
uniprot id: W5LZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

7918:polr1a
gene id: 7918:polr1a
uniprot id: W5MYA4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

7918:sgcz
gene id: 7918:sgcz
uniprot id: W5N9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

7918:slco4c1
gene id: 7918:slco4c1
uniprot id: W5MRT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

7918:pknox2
gene id: 7918:pknox2
uniprot id: W5MDF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

7918:LOC102690781
gene id: 7918:LOC102690781
uniprot id: W5NB17
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

7918:rab9a
gene id: 7918:rab9a
uniprot id: W5NLL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

7918:slc7a2
gene id: 7918:slc7a2
uniprot id: W5N946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

7918:rragc
gene id: 7918:rragc
uniprot id: W5MF20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

7918:LOC102693175
gene id: 7918:LOC102693175
uniprot id: W5M7B2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:mrgbp
gene id: 7918:mrgbp
uniprot id: W5M8Y5
uniprot id: W5M902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

7918:LOC102690812
gene id: 7918:LOC102690812
uniprot id: W5NCS6
names: Similarity
messages: Belongs to the calreticulin family.

7918:crebl2
gene id: 7918:crebl2
uniprot id: W5NIB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

7918:slc5a7
gene id: 7918:slc5a7
uniprot id: W5MWI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

7918:ube2d3
gene id: 7918:ube2d3
uniprot id: W5N4F2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:nav3
gene id: 7918:nav3
uniprot id: W5NHH7
names: Similarity
messages: Belongs to the Nav/unc-53 family.

7918:il1rapl1
gene id: 7918:il1rapl1
uniprot id: W5MSP3
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

7918:nrf1
gene id: 7918:nrf1
uniprot id: W5NG93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

7918:me1
gene id: 7918:me1
uniprot id: W5NKE6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

7918:ace
gene id: 7918:ace
uniprot id: W5N3G1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

7918:clg9h7orf25
gene id: 7918:clg9h7orf25
uniprot id: W5N1Z4
names: Similarity
messages: Belongs to the UPF0415 family.

7918:zeb1
gene id: 7918:zeb1
uniprot id: W5MK51
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

7918:LOC102687474
gene id: 7918:LOC102687474
uniprot id: W5N312
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

7918:sypl2
gene id: 7918:sypl2
uniprot id: W5N3G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

7918:adcy5
gene id: 7918:adcy5
uniprot id: W5M3J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

7918:tfap2d
gene id: 7918:tfap2d
uniprot id: W5NHQ8
names: Similarity
messages: Belongs to the AP-2 family.

7918:nol8
gene id: 7918:nol8
uniprot id: W5N8Y8
names: Subcellular Location Annotation
messages: nucleolus

7918:gpr39
gene id: 7918:gpr39
uniprot id: W5M500
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:LOC102694168
gene id: 7918:LOC102694168
uniprot id: W5MMC3
names: Similarity
messages: Belongs to the globin family.

7918:wnt3a
gene id: 7918:wnt3a
uniprot id: W5MS70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

7918:chd5
gene id: 7918:chd5
uniprot id: W5MC98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

7918:rps13
gene id: 7918:rps13
uniprot id: W5M556
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

7918:blm
gene id: 7918:blm
uniprot id: W5NAF0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

7918:LOC102691961
gene id: 7918:LOC102691961
uniprot id: W5M7C5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane

7918:npffr1
gene id: 7918:npffr1
uniprot id: W5MCV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

7918:arl3
gene id: 7918:arl3
uniprot id: W5N4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

7918:grik1
gene id: 7918:grik1
uniprot id: W5MRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

7918:LOC102698311
gene id: 7918:LOC102698311
uniprot id: W5M944
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

7918:nxpe3
gene id: 7918:nxpe3
uniprot id: W5MTI6
names: Similarity
messages: Belongs to the NXPE family.

7918:hacd4
gene id: 7918:hacd4
uniprot id: W5MZJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:kcnh6
gene id: 7918:kcnh6
uniprot id: W5N1P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily.
messages: Membrane

7918:mctp1
gene id: 7918:mctp1
uniprot id: W5M089
names: Subcellular Location Annotation
messages: Membrane

7918:pmp22
gene id: 7918:pmp22
uniprot id: W5N6C2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:fam136a
gene id: 7918:fam136a
uniprot id: W5NF72
names: Similarity
messages: Belongs to the FAM136 family.

7918:ctbs
gene id: 7918:ctbs
uniprot id: W5MVC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Lysosome

7918:ppp2r2b
gene id: 7918:ppp2r2b
uniprot id: W5MS76
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

7918:vwc2
gene id: 7918:vwc2
uniprot id: W5MCB8
names: Subcellular Location Annotation
messages: Synapse

7918:slc25a15
gene id: 7918:slc25a15
uniprot id: W5MQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

7918:gabra2
gene id: 7918:gabra2
uniprot id: W5N3N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

7918:vps37a
gene id: 7918:vps37a
uniprot id: W5N969
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

7918:xk
gene id: 7918:xk
uniprot id: W5MMA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

7918:cenpo
gene id: 7918:cenpo
uniprot id: W5NG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

7918:stmn4
gene id: 7918:stmn4
uniprot id: W5NG85
names: Similarity
messages: Belongs to the stathmin family.

7918:star
gene id: 7918:star
uniprot id: W5NDE8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

7918:rpsa
gene id: 7918:rpsa
uniprot id: W5N2E1
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

7918:evl
gene id: 7918:evl
uniprot id: W5N0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: cytoskeleton

7918:galnt13
gene id: 7918:galnt13
uniprot id: W5MEQ0
uniprot id: W5MES0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

7918:rbfox3
gene id: 7918:rbfox3
uniprot id: W5N392
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

7918:rps3
gene id: 7918:rps3
uniprot id: W5MH79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: spindle

7918:slc12a4
gene id: 7918:slc12a4
uniprot id: W5MJC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

7918:mcm8
gene id: 7918:mcm8
uniprot id: W5NI58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

7918:ndrg3
gene id: 7918:ndrg3
uniprot id: W5M9L8
names: Similarity
messages: Belongs to the NDRG family.

7918:LOC102683224
gene id: 7918:LOC102683224
uniprot id: W5NJ98
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

7918:npy4r
gene id: 7918:npy4r
uniprot id: W5NNY2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

7918:dnah3
gene id: 7918:dnah3
uniprot id: W5MMU7
names: Similarity
messages: Belongs to the dynein heavy chain family.

7918:atad2b
gene id: 7918:atad2b
uniprot id: W5NIR7
names: Similarity
messages: Belongs to the AAA ATPase family.

7918:taf13
gene id: 7918:taf13
uniprot id: W5M4T1
names: Subcellular Location Annotation
messages: Nucleus

7918:snx2
gene id: 7918:snx2
uniprot id: W5MQE5
uniprot id: W5MQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

7918:LOC102696541
gene id: 7918:LOC102696541
uniprot id: W5MR73
names: Similarity
messages: Belongs to the MS4A family.

7918:acvr2b
gene id: 7918:acvr2b
uniprot id: W5MUV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

7918:gdf7
gene id: 7918:gdf7
uniprot id: W5NKV5
names: Similarity
messages: Belongs to the TGF-beta family.

7918:dmrta2
gene id: 7918:dmrta2
uniprot id: W5MST1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

7918:tspan15
gene id: 7918:tspan15
uniprot id: W5MS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

7918:riok2
gene id: 7918:riok2
uniprot id: W5MHB1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

7918:LOC102686030
gene id: 7918:LOC102686030
uniprot id: W5MSY7
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

7918:supt3h
gene id: 7918:supt3h
uniprot id: W5NFQ9
names: Subcellular Location Annotation
messages: Nucleus

7918:kansl2
gene id: 7918:kansl2
uniprot id: W5M7B1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

7918:hnf4g
gene id: 7918:hnf4g
uniprot id: W5N7I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

7918:acadm
gene id: 7918:acadm
uniprot id: W5M6Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

7918:LOC102689797
gene id: 7918:LOC102689797
uniprot id: W5N2Y1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:sv2a
gene id: 7918:sv2a
uniprot id: W5MRI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

7918:pdcl
gene id: 7918:pdcl
uniprot id: W5M5E1
names: Similarity
messages: Belongs to the phosducin family.

7918:nox4
gene id: 7918:nox4
uniprot id: W5MK19
names: Subcellular Location Annotation
messages: Membrane

7918:cmas
gene id: 7918:cmas
uniprot id: W5NE59
names: Similarity
messages: Belongs to the CMP-NeuNAc synthase family.

7918:pcmtd1
gene id: 7918:pcmtd1
uniprot id: W5MFI4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

7918:usp33
gene id: 7918:usp33
uniprot id: W5M7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

7918:LOC102691017
gene id: 7918:LOC102691017
uniprot id: W5NJC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

7918:LOC102689884
gene id: 7918:LOC102689884
uniprot id: W5MRB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

7918:ppp1r35
gene id: 7918:ppp1r35
uniprot id: W5N7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP1R35 family.
messages: centriole

7918:agxt
gene id: 7918:agxt
uniprot id: W5MHM1
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

7918:gja5
gene id: 7918:gja5
uniprot id: W5NMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:kdsr
gene id: 7918:kdsr
uniprot id: W5N4G9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

7918:sept8
gene id: 7918:sept8
uniprot id: W5MXE1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

7918:rexo4
gene id: 7918:rexo4
uniprot id: W5M787
names: Similarity
messages: Belongs to the REXO4 family.

7918:igf2bp2
gene id: 7918:igf2bp2
uniprot id: W5MTI5
names: Similarity
messages: Belongs to the RRM IMP/VICKZ family.

7918:rpl26l1
gene id: 7918:rpl26l1
uniprot id: W5MS47
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

7918:c9
gene id: 7918:c9
uniprot id: W5N031
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:LOC102691138
gene id: 7918:LOC102691138
uniprot id: W5MVA8
uniprot id: W5MVB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

7918:ccr6
gene id: 7918:ccr6
uniprot id: W5NMX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

7918:c3
gene id: 7918:c3
uniprot id: W5MRT4
names: Subcellular Location Annotation
messages: Secreted

7918:ano6
gene id: 7918:ano6
uniprot id: W5NI34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Cell membrane
messages: Membrane

7918:trhr
gene id: 7918:trhr
uniprot id: W5M5G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

7918:phb2
gene id: 7918:phb2
uniprot id: W5LZN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

7918:nap1l1
gene id: 7918:nap1l1
uniprot id: W5NHG2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

7918:mfn2
gene id: 7918:mfn2
uniprot id: W5MDP2
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

7918:mgat2
gene id: 7918:mgat2
uniprot id: W5NMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

7918:rpl7
gene id: 7918:rpl7
uniprot id: W5M7W6
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

7918:mfge8
gene id: 7918:mfge8
uniprot id: W5NA61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:timm17b
gene id: 7918:timm17b
uniprot id: W5NC32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

7918:spg7
gene id: 7918:spg7
uniprot id: W5MAM5
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

7918:LOC102684806
gene id: 7918:LOC102684806
uniprot id: W5N3T2
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

7918:LOC102690478
gene id: 7918:LOC102690478
uniprot id: W5NGI6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

7918:mat2a
gene id: 7918:mat2a
uniprot id: W5NDL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

7918:rpain
gene id: 7918:rpain
uniprot id: W5M4K0
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102694258
gene id: 7918:LOC102694258
uniprot id: W5M5N7
names: Similarity
messages: Belongs to the cytochrome P450 family.

7918:LOC102685731
gene id: 7918:LOC102685731
uniprot id: W5N4Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

7918:ints9
gene id: 7918:ints9
uniprot id: W5NGE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

7918:LOC102699125
gene id: 7918:LOC102699125
uniprot id: W5MXP4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

7918:atg4c
gene id: 7918:atg4c
uniprot id: W5MHZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

7918:alx3
gene id: 7918:alx3
uniprot id: W5N151
names: Subcellular Location Annotation
messages: Nucleus

7918:usp39
gene id: 7918:usp39
uniprot id: W5NDL5
names: Subcellular Location Annotation
messages: Nucleus

7918:runx3
gene id: 7918:runx3
uniprot id: W5M4C4
names: Subcellular Location Annotation
messages: Nucleus

7918:gjc2
gene id: 7918:gjc2
uniprot id: W5NNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

7918:gale
gene id: 7918:gale
uniprot id: W5M101
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
messages: Homodimer.

7918:ncoa2
gene id: 7918:ncoa2
uniprot id: W5M971
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

7918:LOC102682401
gene id: 7918:LOC102682401
uniprot id: W5LXI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

7918:kctd20
gene id: 7918:kctd20
uniprot id: W5N0K8
names: Subcellular Location Annotation
messages: Cytoplasm

7918:kif1bp
gene id: 7918:kif1bp
uniprot id: W5MRY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

7918:LOC102689374
gene id: 7918:LOC102689374
uniprot id: W5NM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

7918:st6galnac5
gene id: 7918:st6galnac5
uniprot id: W5M768
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:kdm4c
gene id: 7918:kdm4c
uniprot id: W5N6Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM3 histone demethylase family.
messages: Nucleus

7918:acox1
gene id: 7918:acox1
uniprot id: W5N7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

7918:slc5a5
gene id: 7918:slc5a5
uniprot id: W5M4I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

7918:ttc9
gene id: 7918:ttc9
uniprot id: W5N9J7
names: Similarity
messages: Belongs to the TTC9 family.

7918:pkd1
gene id: 7918:pkd1
uniprot id: W5M582
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:ptprg
gene id: 7918:ptprg
uniprot id: W5MWP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

7918:pde7a
gene id: 7918:pde7a
uniprot id: W5MBR0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

7918:vip
gene id: 7918:vip
uniprot id: W5NEM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

7918:rgs7bp
gene id: 7918:rgs7bp
uniprot id: W5MML7
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

7918:LOC102685247
gene id: 7918:LOC102685247
uniprot id: W5N2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

7918:LOC107078254
gene id: 7918:LOC107078254
uniprot id: W5N0F6
names: Similarity
messages: Belongs to the VPS8 family.

7918:lhx9
gene id: 7918:lhx9
uniprot id: W5MLF4
uniprot id: W5MLH3
names: Subcellular Location Annotation
messages: Nucleus

7918:dcaf13
gene id: 7918:dcaf13
uniprot id: W5MTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

7918:trmt6
gene id: 7918:trmt6
uniprot id: W5NI61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

7918:LOC107078395
gene id: 7918:LOC107078395
uniprot id: W5MHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

7918:ccno
gene id: 7918:ccno
uniprot id: W5M3F7
names: Similarity
messages: Belongs to the cyclin family.

7918:map2k2
gene id: 7918:map2k2
uniprot id: W5MFR2
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:fam83f
gene id: 7918:fam83f
uniprot id: W5MZZ8
names: Similarity
messages: Belongs to the FAM83 family.

7918:LOC102693569
gene id: 7918:LOC102693569
uniprot id: W5MM94
names: Similarity
messages: Belongs to the globin family.

7918:tbx20
gene id: 7918:tbx20
uniprot id: W5M3G0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

7918:prpf38a
gene id: 7918:prpf38a
uniprot id: W5MGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

7918:palm
gene id: 7918:palm
uniprot id: W5M0W5
names: Similarity
messages: Belongs to the paralemmin family.

7918:mrps9
gene id: 7918:mrps9
uniprot id: W5MQG1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

7918:galc
gene id: 7918:galc
uniprot id: W5MPZ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

7918:hoxb6
gene id: 7918:hoxb6
uniprot id: W5N7G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

7918:pspn
gene id: 7918:pspn
uniprot id: W5MH19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

7918:aqp4
gene id: 7918:aqp4
uniprot id: W5MGW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

7918:prim2
gene id: 7918:prim2
uniprot id: W5NK70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

7918:degs2
gene id: 7918:degs2
uniprot id: W5N0Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:LOC102694040
gene id: 7918:LOC102694040
uniprot id: W5MS84
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:mief1
gene id: 7918:mief1
uniprot id: W5MZ45
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

7918:LOC102694570
gene id: 7918:LOC102694570
uniprot id: W5M9Y9
names: Similarity
messages: Belongs to the histone H3 family.

7918:nkain1
gene id: 7918:nkain1
uniprot id: W5MD36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

7918:pnrc1
gene id: 7918:pnrc1
uniprot id: W5NJX6
names: Subcellular Location Annotation
messages: Nucleus

7918:asxl3
gene id: 7918:asxl3
uniprot id: W5MGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

7918:bet1
gene id: 7918:bet1
uniprot id: W5MY13
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102698310
gene id: 7918:LOC102698310
uniprot id: W5MC54
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

7918:LOC102687550
gene id: 7918:LOC102687550
uniprot id: W5MWH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

7918:idh3b
gene id: 7918:idh3b
uniprot id: W5LYM0
uniprot id: W5LYN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

7918:llgl2
gene id: 7918:llgl2
uniprot id: W5N0C0
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

7918:tmem50a
gene id: 7918:tmem50a
uniprot id: W5M467
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

7918:leprot
gene id: 7918:leprot
uniprot id: W5MIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

7918:ca12
gene id: 7918:ca12
uniprot id: W5NCG8
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

7918:mturn
gene id: 7918:mturn
uniprot id: W5M1C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

7918:LOC102687363
gene id: 7918:LOC102687363
uniprot id: W5M1J9
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

7918:riok1
gene id: 7918:riok1
uniprot id: W5N1B2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

7918:eya4
gene id: 7918:eya4
uniprot id: W5NHA6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

7918:lace1
gene id: 7918:lace1
uniprot id: W5NIP9
names: Similarity
messages: Belongs to the AFG1 ATPase family.

7918:LOC107077393
gene id: 7918:LOC107077393
uniprot id: W5N0M3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:fam160a1
gene id: 7918:fam160a1
uniprot id: W5MPY6
names: Similarity
messages: Belongs to the FHIP family.

7918:rfng
gene id: 7918:rfng
uniprot id: W5N3K8
names: Subcellular Location Annotation
messages: Membrane

7918:st8sia2
gene id: 7918:st8sia2
uniprot id: W5NAP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

7918:LOC102697781
gene id: 7918:LOC102697781
uniprot id: W5LXG1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

7918:dlx6
gene id: 7918:dlx6
uniprot id: W5MYP4
names: Subcellular Location Annotation
messages: Nucleus

7918:tmprss6
gene id: 7918:tmprss6
uniprot id: W5MZC9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:hmgcll1
gene id: 7918:hmgcll1
uniprot id: W5NJU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

7918:pno1
gene id: 7918:pno1
uniprot id: W5NGH1
names: Subcellular Location Annotation
messages: nucleolus

7918:fam20b
gene id: 7918:fam20b
uniprot id: W5MWW7
names: Similarity
messages: Belongs to the FAM20 family.

7918:med14
gene id: 7918:med14
uniprot id: W5M2W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

7918:ppp3ca
gene id: 7918:ppp3ca
uniprot id: W5MZT4
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

7918:cdc26
gene id: 7918:cdc26
uniprot id: W5LWU5
names: Similarity
messages: Belongs to the CDC26 family.

7918:LOC102685258
gene id: 7918:LOC102685258
uniprot id: W5MXP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

7918:mid1ip1
gene id: 7918:mid1ip1
uniprot id: W5NMN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

7918:kifc3
gene id: 7918:kifc3
uniprot id: W5MGA2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

7918:tsen2
gene id: 7918:tsen2
uniprot id: W5N998
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

7918:LOC102691967
gene id: 7918:LOC102691967
uniprot id: W5M846
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

7918:nop14
gene id: 7918:nop14
uniprot id: W5N0W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

7918:LOC102693421
gene id: 7918:LOC102693421
uniprot id: W5MNH7
names: Subcellular Location Annotation
messages: Membrane

7918:kiaa1024
gene id: 7918:kiaa1024
uniprot id: W5N4Z3
names: Similarity
messages: Belongs to the MINAR family.

7918:npy
gene id: 7918:npy
uniprot id: W5N110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

7918:rapgef2
gene id: 7918:rapgef2
uniprot id: W5MMX4
names: Similarity
messages: Belongs to the RAPGEF2 family.

7918:zbed1
gene id: 7918:zbed1
uniprot id: W5NLL1
names: Subcellular Location Annotation
messages: Nucleus

7918:LOC102684237
gene id: 7918:LOC102684237
uniprot id: W5M152
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

7918:kcna10
gene id: 7918:kcna10
uniprot id: W5NNF9
names: Subcellular Location Annotation
messages: Membrane

7918:allc
gene id: 7918:allc
uniprot id: W5NKW7
names: Similarity
messages: Belongs to the allantoicase family.

7918:eya1
gene id: 7918:eya1
uniprot id: W5M8N7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

7918:LOC102695039
gene id: 7918:LOC102695039
uniprot id: W5MMW1
names: Similarity
messages: Belongs to the S-100 family.

7918:LOC102685823
gene id: 7918:LOC102685823
uniprot id: W5M5K4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

7918:phactr3
gene id: 7918:phactr3
uniprot id: W5M684
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

7918:plxnc1
gene id: 7918:plxnc1
uniprot id: W5NFK2
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

7918:nes
gene id: 7918:nes
uniprot id: W5MNG1
names: Similarity
messages: Belongs to the intermediate filament family.

7918:greb1l
gene id: 7918:greb1l
uniprot id: W5M1M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

7918:LOC102686288
gene id: 7918:LOC102686288
uniprot id: W5NJS7
names: Subcellular Location Annotation
messages: Nucleus

7918:en2
gene id: 7918:en2
uniprot id: W5N432
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

7918:dync1li2
gene id: 7918:dync1li2
uniprot id: W5MCH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

7918:LOC102688208
gene id: 7918:LOC102688208
uniprot id: W5ME36
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

7918:park7
gene id: 7918:park7
uniprot id: W5M885
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

7918:ube2n
gene id: 7918:ube2n
uniprot id: W5NDU6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

7918:dctpp1
gene id: 7918:dctpp1
uniprot id: W5M4C3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homotetramer.
messages: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
messages: cytosol

7918:rhebl1
gene id: 7918:rhebl1
uniprot id: W5MLR9
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

7918:pdia2
gene id: 7918:pdia2
uniprot id: W5MGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

7918:ppm1k
gene id: 7918:ppm1k
uniprot id: W5N7F6
names: Similarity
messages: Belongs to the PP2C family.

7918:LOC102687355
gene id: 7918:LOC102687355
uniprot id: W5NLT0
names: Similarity
messages: Belongs to the peptidase S1B family.

7918:trio
gene id: 7918:trio
uniprot id: W5LXL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

7918:rcan2
gene id: 7918:rcan2
uniprot id: W5NFZ8
uniprot id: W5NFZ9
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

7918:pik3r1
gene id: 7918:pik3r1
uniprot id: W5MWY0
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

7918:ptpn14
gene id: 7918:ptpn14
uniprot id: W5NJ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

7918:polr1c
gene id: 7918:polr1c
uniprot id: W5NJ37
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

7918:LOC102695277
gene id: 7918:LOC102695277
uniprot id: W5N6A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

7918:mdh2
gene id: 7918:mdh2
uniprot id: W5M0R3
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

7918:tram1
gene id: 7918:tram1
uniprot id: W5M8Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

7918:chrna10
gene id: 7918:chrna10
uniprot id: W5MN18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:rsad1
gene id: 7918:rsad1
uniprot id: W5N9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Mitochondrion

7918:arpc5
gene id: 7918:arpc5
uniprot id: W5M0I3
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

7918:gna13
gene id: 7918:gna13
uniprot id: W5N3Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

7918:sbds
gene id: 7918:sbds
uniprot id: W5M906
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

7918:gabra4
gene id: 7918:gabra4
uniprot id: W5N3M6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

7918:sgk1
gene id: 7918:sgk1
uniprot id: W5NH98
names: Similarity
messages: Belongs to the protein kinase superfamily.

7918:ptrf
gene id: 7918:ptrf
uniprot id: W5N437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

7918:kcnq3
gene id: 7918:kcnq3
uniprot id: W5N4S1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:tbk1
gene id: 7918:tbk1
uniprot id: W5NIA8
names: Subcellular Location Annotation
messages: Cytoplasm

7918:adamts12
gene id: 7918:adamts12
uniprot id: W5N3H7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

7918:rpl37a
gene id: 7918:rpl37a
uniprot id: W5MU68
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

7918:LOC102697922
gene id: 7918:LOC102697922
uniprot id: W5NJ47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate.

7918:srfbp1
gene id: 7918:srfbp1
uniprot id: W5MQL9
names: Function
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

7918:hnmt
gene id: 7918:hnmt
uniprot id: W5LY96
names: Subunit
messages: Monomer.

7918:gpr146
gene id: 7918:gpr146
uniprot id: W5NNJ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

7918:hgf
gene id: 7918:hgf
uniprot id: W5NEQ8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

7918:pqlc2
gene id: 7918:pqlc2
uniprot id: W5ML77
names: Subcellular Location Annotation
messages: Membrane

7918:taf12
gene id: 7918:taf12
uniprot id: W5M6W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

7918:ccdc85c
gene id: 7918:ccdc85c
uniprot id: W5MQG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

7918:LOC102692627
gene id: 7918:LOC102692627
uniprot id: W5MHG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

7918:sec61a2
gene id: 7918:sec61a2
uniprot id: W5NFC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:lin28b
gene id: 7918:lin28b
uniprot id: W5NIG6
names: Similarity
messages: Belongs to the lin-28 family.

7918:nup35
gene id: 7918:nup35
uniprot id: W5MIA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

7918:snd1
gene id: 7918:snd1
uniprot id: W5NER8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

7918:ltc4s
gene id: 7918:ltc4s
uniprot id: W5N074
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

7918:clg13h16orf72
gene id: 7918:clg13h16orf72
uniprot id: W5MGL0
names: Subcellular Location Annotation
messages: Nucleus

7918:slc35d2
gene id: 7918:slc35d2
uniprot id: W5MS87
names: Subcellular Location Annotation
messages: Membrane

7918:LOC102695460
gene id: 7918:LOC102695460
uniprot id: W5MZG2
names: Similarity
messages: Belongs to the peptidase M14 family.

7918:trmt2a
gene id: 7918:trmt2a
uniprot id: W5M3K3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.