768670:CALNI RS01740
gene id: 768670:CALNI_RS01740
uniprot id: E4TK14
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

768670:CALNI RS01640
gene id: 768670:CALNI_RS01640
uniprot id: E4TJZ4
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

768670:CALNI RS08960
gene id: 768670:CALNI_RS08960
uniprot id: E4TG93
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

768670:CALNI RS09540
gene id: 768670:CALNI_RS09540
uniprot id: E4TGZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS10070
gene id: 768670:CALNI_RS10070
uniprot id: E4THE8
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

768670:CALNI RS05175
gene id: 768670:CALNI_RS05175
uniprot id: E4TI15
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

768670:CALNI RS06035
gene id: 768670:CALNI_RS06035
uniprot id: E4TIY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

768670:CALNI RS05305
gene id: 768670:CALNI_RS05305
uniprot id: E4TI54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

768670:CALNI RS04150
gene id: 768670:CALNI_RS04150
uniprot id: E4TGY1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS03420
gene id: 768670:CALNI_RS03420
uniprot id: E4TG45
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

768670:CALNI RS03870
gene id: 768670:CALNI_RS03870
uniprot id: E4TGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

768670:CALNI RS02310
gene id: 768670:CALNI_RS02310
uniprot id: E4TEW9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

768670:CALNI RS06335
gene id: 768670:CALNI_RS06335
uniprot id: E4TJA5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

768670:CALNI RS09030
gene id: 768670:CALNI_RS09030
uniprot id: E4TGA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

768670:CALNI RS09040
gene id: 768670:CALNI_RS09040
uniprot id: E4TGA9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

768670:CALNI RS10185
gene id: 768670:CALNI_RS10185
uniprot id: E4THH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

768670:CALNI RS00130
gene id: 768670:CALNI_RS00130
uniprot id: E4TIB8
names: Subcellular Location Annotation
messages: Cytoplasm

768670:CALNI RS07060
gene id: 768670:CALNI_RS07060
uniprot id: E4TK32
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS07180
gene id: 768670:CALNI_RS07180
uniprot id: E4TK56
names: Subcellular Location Annotation
messages: Cytoplasm

768670:CALNI RS01540
gene id: 768670:CALNI_RS01540
uniprot id: E4TJX3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

768670:CALNI RS05620
gene id: 768670:CALNI_RS05620
uniprot id: E4TII5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

768670:CALNI RS05950
gene id: 768670:CALNI_RS05950
uniprot id: E4TIW3
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

768670:CALNI RS09360
gene id: 768670:CALNI_RS09360
uniprot id: E4TGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS06030
gene id: 768670:CALNI_RS06030
uniprot id: E4TIY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS10075
gene id: 768670:CALNI_RS10075
uniprot id: E4THE9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

768670:CALNI RS09330
gene id: 768670:CALNI_RS09330
uniprot id: E4TGP1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

768670:CALNI RS09055
gene id: 768670:CALNI_RS09055
uniprot id: E4TGB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

768670:CALNI RS06880
gene id: 768670:CALNI_RS06880
uniprot id: E4TJS6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

768670:CALNI RS01960
gene id: 768670:CALNI_RS01960
uniprot id: E4TEH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

768670:CALNI RS03425
gene id: 768670:CALNI_RS03425
uniprot id: E4TG46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

768670:CALNI RS04930
gene id: 768670:CALNI_RS04930
uniprot id: E4THW7
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

768670:CALNI RS07525
gene id: 768670:CALNI_RS07525
uniprot id: E4TEP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

768670:CALNI RS06505
gene id: 768670:CALNI_RS06505
uniprot id: E4TJD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

768670:CALNI RS02465
gene id: 768670:CALNI_RS02465
uniprot id: E4TF66
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS02620
gene id: 768670:CALNI_RS02620
uniprot id: E4TF97
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

768670:CALNI RS08295
gene id: 768670:CALNI_RS08295
uniprot id: E4TFH7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

768670:CALNI RS04340
gene id: 768670:CALNI_RS04340
uniprot id: E4TH85
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

768670:CALNI RS05030
gene id: 768670:CALNI_RS05030
uniprot id: E4THY7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS05080
gene id: 768670:CALNI_RS05080
uniprot id: E4THZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

768670:CALNI RS08185
gene id: 768670:CALNI_RS08185
uniprot id: E4TFF5
names: Similarity
messages: Belongs to the Lgt family.

768670:CALNI RS05270
gene id: 768670:CALNI_RS05270
uniprot id: E4TI47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS00480
gene id: 768670:CALNI_RS00480
uniprot id: E4TIQ6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

768670:CALNI RS07195
gene id: 768670:CALNI_RS07195
uniprot id: E4TK59
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

768670:CALNI RS08695
gene id: 768670:CALNI_RS08695
uniprot id: E4TFX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

768670:CALNI RS05300
gene id: 768670:CALNI_RS05300
uniprot id: E4TI53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

768670:CALNI RS02590
gene id: 768670:CALNI_RS02590
uniprot id: E4TF91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

768670:CALNI RS09935
gene id: 768670:CALNI_RS09935
uniprot id: E4THC2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS02440
gene id: 768670:CALNI_RS02440
uniprot id: E4TEZ4
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS02575
gene id: 768670:CALNI_RS02575
uniprot id: E4TF88
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

768670:CALNI RS05215
gene id: 768670:CALNI_RS05215
uniprot id: E4TI36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

768670:CALNI RS09365
gene id: 768670:CALNI_RS09365
uniprot id: E4TGP8
names: Similarity
messages: Belongs to the LOG family.

768670:CALNI RS04380
gene id: 768670:CALNI_RS04380
uniprot id: E4TH93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

768670:CALNI RS10055
gene id: 768670:CALNI_RS10055
uniprot id: E4THE5
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS07620
gene id: 768670:CALNI_RS07620
uniprot id: E4TER5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

768670:CALNI RS05965
gene id: 768670:CALNI_RS05965
uniprot id: E4TIW6
names: Similarity
messages: Belongs to the DtxR/MntR family.

768670:CALNI RS04985
gene id: 768670:CALNI_RS04985
uniprot id: E4THX8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

768670:CALNI RS06365
gene id: 768670:CALNI_RS06365
uniprot id: E4TJB1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

768670:CALNI RS01710
gene id: 768670:CALNI_RS01710
uniprot id: E4TK08
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

768670:CALNI RS06445
gene id: 768670:CALNI_RS06445
uniprot id: E4TJC7
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS03175
gene id: 768670:CALNI_RS03175
uniprot id: E4TFZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

768670:CALNI RS04880
gene id: 768670:CALNI_RS04880
uniprot id: E4THV7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

768670:CALNI RS05040
gene id: 768670:CALNI_RS05040
uniprot id: E4THY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

768670:CALNI RS07110
gene id: 768670:CALNI_RS07110
uniprot id: E4TK42
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

768670:CALNI RS08270
gene id: 768670:CALNI_RS08270
uniprot id: E4TFH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

768670:CALNI RS00815
gene id: 768670:CALNI_RS00815
uniprot id: E4TJ44
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS00285
gene id: 768670:CALNI_RS00285
uniprot id: E4TIE9
names: Similarity
messages: Belongs to the RecJ family.

768670:CALNI RS08700
gene id: 768670:CALNI_RS08700
uniprot id: E4TFX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS03450
gene id: 768670:CALNI_RS03450
uniprot id: E4TG51
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

768670:CALNI RS10220
gene id: 768670:CALNI_RS10220
uniprot id: E4THH7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

768670:CALNI RS08980
gene id: 768670:CALNI_RS08980
uniprot id: E4TG97
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

768670:CALNI RS04990
gene id: 768670:CALNI_RS04990
uniprot id: E4THX9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

768670:CALNI RS05910
gene id: 768670:CALNI_RS05910
uniprot id: E4TIP0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

768670:CALNI RS03430
gene id: 768670:CALNI_RS03430
uniprot id: E4TG47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

768670:CALNI RS02705
gene id: 768670:CALNI_RS02705
uniprot id: E4TFB4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS00665
gene id: 768670:CALNI_RS00665
uniprot id: E4TIU4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

768670:CALNI RS08250
gene id: 768670:CALNI_RS08250
uniprot id: E4TFG8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

768670:CALNI RS02450
gene id: 768670:CALNI_RS02450
uniprot id: E4TEZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

768670:CALNI RS00645
gene id: 768670:CALNI_RS00645
uniprot id: E4TIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

768670:CALNI RS01850
gene id: 768670:CALNI_RS01850
uniprot id: E4TEG1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

768670:CALNI RS09590
gene id: 768670:CALNI_RS09590
uniprot id: E4TH07
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS08690
gene id: 768670:CALNI_RS08690
uniprot id: E4TFX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

768670:CALNI RS06105
gene id: 768670:CALNI_RS06105
uniprot id: E4TIZ4
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS01135
gene id: 768670:CALNI_RS01135
uniprot id: E4TJI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

768670:CALNI RS03760
gene id: 768670:CALNI_RS03760
uniprot id: E4TGI3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS07510
gene id: 768670:CALNI_RS07510
uniprot id: E4TEP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

768670:CALNI RS07480
gene id: 768670:CALNI_RS07480
uniprot id: E4TEN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

768670:CALNI RS08385
gene id: 768670:CALNI_RS08385
uniprot id: E4TFJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

768670:CALNI RS07960
gene id: 768670:CALNI_RS07960
uniprot id: E4TF45
names: Similarity
messages: Belongs to the UPF0235 family.

768670:CALNI RS05035
gene id: 768670:CALNI_RS05035
uniprot id: E4THY8
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

768670:CALNI RS04070
gene id: 768670:CALNI_RS04070
uniprot id: E4TGW4
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS01310
gene id: 768670:CALNI_RS01310
uniprot id: E4TJL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

768670:CALNI RS00045
gene id: 768670:CALNI_RS00045
uniprot id: E4TI29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

768670:CALNI RS00275
gene id: 768670:CALNI_RS00275
uniprot id: E4TIE7
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

768670:CALNI RS10720
gene id: 768670:CALNI_RS10720
uniprot id: E4TKD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

768670:CALNI RS07715
gene id: 768670:CALNI_RS07715
uniprot id: E4TEZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

768670:CALNI RS02845
gene id: 768670:CALNI_RS02845
uniprot id: E4TFL3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

768670:CALNI RS07970
gene id: 768670:CALNI_RS07970
uniprot id: E4TF47
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

768670:CALNI RS08040
gene id: 768670:CALNI_RS08040
uniprot id: E4TF61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

768670:CALNI RS00030
gene id: 768670:CALNI_RS00030
uniprot id: E4TI26
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

768670:CALNI RS04420
gene id: 768670:CALNI_RS04420
uniprot id: E4THA1
names: Cofactor
messages: Binds 1 FAD per subunit.

768670:CALNI RS07905
gene id: 768670:CALNI_RS07905
uniprot id: E4TF35
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

768670:CALNI RS04505
gene id: 768670:CALNI_RS04505
uniprot id: E4THI6
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

768670:CALNI RS02585
gene id: 768670:CALNI_RS02585
uniprot id: E4TF90
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

768670:CALNI RS07500
gene id: 768670:CALNI_RS07500
uniprot id: E4TEP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

768670:CALNI RS04265
gene id: 768670:CALNI_RS04265
uniprot id: E4TH70
names: Similarity
messages: Belongs to the serpin family.

768670:CALNI RS10730
gene id: 768670:CALNI_RS10730
uniprot id: E4TKE1
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

768670:CALNI RS01530
gene id: 768670:CALNI_RS01530
uniprot id: E4TJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS02610
gene id: 768670:CALNI_RS02610
uniprot id: E4TF95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS05990
gene id: 768670:CALNI_RS05990
uniprot id: E4TIX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

768670:CALNI RS01140
gene id: 768670:CALNI_RS01140
uniprot id: E4TJI3
names: Similarity
messages: Belongs to the peptidase M24B family.

768670:CALNI RS11370
gene id: 768670:CALNI_RS11370
uniprot id: E4TJA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

768670:CALNI RS02115
gene id: 768670:CALNI_RS02115
uniprot id: E4TET1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

768670:CALNI RS06250
gene id: 768670:CALNI_RS06250
uniprot id: E4TJ23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS05335
gene id: 768670:CALNI_RS05335
uniprot id: E4TI59
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

768670:CALNI RS06145
gene id: 768670:CALNI_RS06145
uniprot id: E4TJ02
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

768670:CALNI RS10460
gene id: 768670:CALNI_RS10460
uniprot id: E4THV1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

768670:CALNI RS02045
gene id: 768670:CALNI_RS02045
uniprot id: E4TEJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS02860
gene id: 768670:CALNI_RS02860
uniprot id: E4TFL6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

768670:CALNI RS10690
gene id: 768670:CALNI_RS10690
uniprot id: E4TKD3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

768670:CALNI RS09150
gene id: 768670:CALNI_RS09150
uniprot id: E4TGK5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

768670:CALNI RS03890
gene id: 768670:CALNI_RS03890
uniprot id: E4TGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS01560
gene id: 768670:CALNI_RS01560
uniprot id: E4TJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

768670:CALNI RS06720
gene id: 768670:CALNI_RS06720
uniprot id: E4TJQ3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

768670:CALNI RS00040
gene id: 768670:CALNI_RS00040
uniprot id: E4TI28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS08715
gene id: 768670:CALNI_RS08715
uniprot id: E4TFX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

768670:CALNI RS06005
gene id: 768670:CALNI_RS06005
uniprot id: E4TIX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

768670:CALNI RS03695
gene id: 768670:CALNI_RS03695
uniprot id: E4TGG9
names: Function
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.

768670:CALNI RS00225
gene id: 768670:CALNI_RS00225
uniprot id: E4TID7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

768670:CALNI RS01880
gene id: 768670:CALNI_RS01880
uniprot id: E4TEG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

768670:CALNI RS01450
gene id: 768670:CALNI_RS01450
uniprot id: E4TJV5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

768670:CALNI RS04955
gene id: 768670:CALNI_RS04955
uniprot id: E4THX2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

768670:CALNI RS04315
gene id: 768670:CALNI_RS04315
uniprot id: E4TH80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

768670:CALNI RS08300
gene id: 768670:CALNI_RS08300
uniprot id: E4TFH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

768670:CALNI RS07020
gene id: 768670:CALNI_RS07020
uniprot id: E4TK24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

768670:CALNI RS05915
gene id: 768670:CALNI_RS05915
uniprot id: E4TIP1
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

768670:CALNI RS02230
gene id: 768670:CALNI_RS02230
uniprot id: E4TEV3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

768670:CALNI RS01650
gene id: 768670:CALNI_RS01650
uniprot id: E4TJZ6
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

768670:CALNI RS11020
gene id: 768670:CALNI_RS11020
uniprot id: E4TKB8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

768670:CALNI RS02930
gene id: 768670:CALNI_RS02930
uniprot id: E4TFN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

768670:CALNI RS05595
gene id: 768670:CALNI_RS05595
uniprot id: E4TII0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

768670:CALNI RS05420
gene id: 768670:CALNI_RS05420
uniprot id: E4TI76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

768670:CALNI RS03715
gene id: 768670:CALNI_RS03715
uniprot id: E4TGH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

768670:CALNI RS00050
gene id: 768670:CALNI_RS00050
uniprot id: E4TI30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

768670:CALNI RS02055
gene id: 768670:CALNI_RS02055
uniprot id: E4TEJ8
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

768670:CALNI RS06650
gene id: 768670:CALNI_RS06650
uniprot id: E4TJG8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

768670:CALNI RS02180
gene id: 768670:CALNI_RS02180
uniprot id: E4TEU3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

768670:CALNI RS01690
gene id: 768670:CALNI_RS01690
uniprot id: E4TK04
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

768670:CALNI RS00515
gene id: 768670:CALNI_RS00515
uniprot id: E4TIR3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

768670:CALNI RS00365
gene id: 768670:CALNI_RS00365
uniprot id: E4TIG5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

768670:CALNI RS04850
gene id: 768670:CALNI_RS04850
uniprot id: E4THQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

768670:CALNI RS08365
gene id: 768670:CALNI_RS08365
uniprot id: E4TFJ1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

768670:CALNI RS05685
gene id: 768670:CALNI_RS05685
uniprot id: E4TIJ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

768670:CALNI RS05090
gene id: 768670:CALNI_RS05090
uniprot id: E4THZ8
names: Similarity
messages: Belongs to the YicC/YloC family.

768670:CALNI RS01625
gene id: 768670:CALNI_RS01625
uniprot id: E4TJZ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

768670:CALNI RS09390
gene id: 768670:CALNI_RS09390
uniprot id: E4TGQ3
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

768670:CALNI RS01025
gene id: 768670:CALNI_RS01025
uniprot id: E4TJ86
names: Similarity
messages: Belongs to the hemerythrin family.

768670:CALNI RS02560
gene id: 768670:CALNI_RS02560
uniprot id: E4TF85
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

768670:CALNI RS03750
gene id: 768670:CALNI_RS03750
uniprot id: E4TGI1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

768670:CALNI RS07420
gene id: 768670:CALNI_RS07420
uniprot id: E4TEM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

768670:CALNI RS03490
gene id: 768670:CALNI_RS03490
uniprot id: E4TGC8
names: Similarity
messages: Belongs to the leucine-binding protein family.

768670:CALNI RS03520
gene id: 768670:CALNI_RS03520
uniprot id: E4TGD4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

768670:CALNI RS08390
gene id: 768670:CALNI_RS08390
uniprot id: E4TFJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

768670:CALNI RS11305
gene id: 768670:CALNI_RS11305
uniprot id: E4TJA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

768670:CALNI RS06140
gene id: 768670:CALNI_RS06140
uniprot id: E4TJ01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

768670:CALNI RS02870
gene id: 768670:CALNI_RS02870
uniprot id: E4TFL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

768670:CALNI RS07950
gene id: 768670:CALNI_RS07950
uniprot id: E4TF43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

768670:CALNI RS10110
gene id: 768670:CALNI_RS10110
uniprot id: E4THF5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

768670:CALNI RS10345
gene id: 768670:CALNI_RS10345
uniprot id: E4THS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS02950
gene id: 768670:CALNI_RS02950
uniprot id: E4TFN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

768670:CALNI RS07830
gene id: 768670:CALNI_RS07830
uniprot id: E4TF20
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

768670:CALNI RS06155
gene id: 768670:CALNI_RS06155
uniprot id: E4TJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

768670:CALNI RS07275
gene id: 768670:CALNI_RS07275
uniprot id: E4TK75
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

768670:CALNI RS07475
gene id: 768670:CALNI_RS07475
uniprot id: E4TEN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

768670:CALNI RS06895
gene id: 768670:CALNI_RS06895
uniprot id: E4TJS9
names: Similarity
messages: Belongs to the peptidase M29 family.

768670:CALNI RS07285
gene id: 768670:CALNI_RS07285
uniprot id: E4TK77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

768670:CALNI RS07465
gene id: 768670:CALNI_RS07465
uniprot id: E4TEN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

768670:CALNI RS01380
gene id: 768670:CALNI_RS01380
uniprot id: E4TJN1
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS01495
gene id: 768670:CALNI_RS01495
uniprot id: E4TJW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

768670:CALNI RS04750
gene id: 768670:CALNI_RS04750
uniprot id: E4THN5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

768670:CALNI RS09615
gene id: 768670:CALNI_RS09615
uniprot id: E4TH12
names: Similarity
messages: Belongs to the UPF0251 family.

768670:CALNI RS01565
gene id: 768670:CALNI_RS01565
uniprot id: E4TJX8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

768670:CALNI RS02185
gene id: 768670:CALNI_RS02185
uniprot id: E4TEU4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

768670:CALNI RS04680
gene id: 768670:CALNI_RS04680
uniprot id: E4THM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

768670:CALNI RS09135
gene id: 768670:CALNI_RS09135
uniprot id: E4TGK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS07615
gene id: 768670:CALNI_RS07615
uniprot id: E4TER3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

768670:CALNI RS00315
gene id: 768670:CALNI_RS00315
uniprot id: E4TIF5
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS02655
gene id: 768670:CALNI_RS02655
uniprot id: E4TFA4
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS06965
gene id: 768670:CALNI_RS06965
uniprot id: E4TJU3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

768670:CALNI RS06045
gene id: 768670:CALNI_RS06045
uniprot id: E4TIY3
names: Similarity
messages: Belongs to the GSP E family.

768670:CALNI RS08815
gene id: 768670:CALNI_RS08815
uniprot id: E4TG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS03445
gene id: 768670:CALNI_RS03445
uniprot id: E4TG50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

768670:CALNI RS03390
gene id: 768670:CALNI_RS03390
uniprot id: E4TG39
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

768670:CALNI RS09165
gene id: 768670:CALNI_RS09165
uniprot id: E4TGK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS07345
gene id: 768670:CALNI_RS07345
uniprot id: E4TK89
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

768670:CALNI RS06635
gene id: 768670:CALNI_RS06635
uniprot id: E4TJG5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS03675
gene id: 768670:CALNI_RS03675
uniprot id: E4TGG5
names: Similarity
messages: Belongs to the MotB family.

768670:CALNI RS08665
gene id: 768670:CALNI_RS08665
uniprot id: E4TFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS06540
gene id: 768670:CALNI_RS06540
uniprot id: E4TJE6
names: Similarity
messages: Belongs to the ParB family.

768670:CALNI RS05220
gene id: 768670:CALNI_RS05220
uniprot id: E4TI37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

768670:CALNI RS07210
gene id: 768670:CALNI_RS07210
uniprot id: E4TK62
names: Similarity
messages: Belongs to the sigma-54 factor family.

768670:CALNI RS04960
gene id: 768670:CALNI_RS04960
uniprot id: E4THX3
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

768670:CALNI RS06390
gene id: 768670:CALNI_RS06390
uniprot id: E4TJB6
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

768670:CALNI RS10135
gene id: 768670:CALNI_RS10135
uniprot id: E4THG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

768670:CALNI RS08655
gene id: 768670:CALNI_RS08655
uniprot id: E4TFW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

768670:CALNI RS01230
gene id: 768670:CALNI_RS01230
uniprot id: E4TJK1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

768670:CALNI RS06830
gene id: 768670:CALNI_RS06830
uniprot id: E4TJR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.
messages: Mitochondrion

768670:CALNI RS01120
gene id: 768670:CALNI_RS01120
uniprot id: E4TJH9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS01345
gene id: 768670:CALNI_RS01345
uniprot id: E4TJM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

768670:CALNI RS02410
gene id: 768670:CALNI_RS02410
uniprot id: E4TEY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

768670:CALNI RS01215
gene id: 768670:CALNI_RS01215
uniprot id: E4TJJ8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

768670:CALNI RS06375
gene id: 768670:CALNI_RS06375
uniprot id: E4TJB3
names: Similarity
messages: Belongs to the citrate synthase family.

768670:CALNI RS08020
gene id: 768670:CALNI_RS08020
uniprot id: E4TF57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

768670:CALNI RS04945
gene id: 768670:CALNI_RS04945
uniprot id: E4THX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS03300
gene id: 768670:CALNI_RS03300
uniprot id: E4TG21
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

768670:CALNI RS05375
gene id: 768670:CALNI_RS05375
uniprot id: E4TG93
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

768670:CALNI RS10180
gene id: 768670:CALNI_RS10180
uniprot id: E4THG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

768670:CALNI RS10175
gene id: 768670:CALNI_RS10175
uniprot id: E4THG8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

768670:CALNI RS02295
gene id: 768670:CALNI_RS02295
uniprot id: E4TEW6
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS08380
gene id: 768670:CALNI_RS08380
uniprot id: E4TFJ4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

768670:CALNI RS01070
gene id: 768670:CALNI_RS01070
uniprot id: E4TJG9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

768670:CALNI RS01080
gene id: 768670:CALNI_RS01080
uniprot id: E4TJH1
names: Similarity
messages: Belongs to the FlgM family.

768670:CALNI RS02015
gene id: 768670:CALNI_RS02015
uniprot id: E4TEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane

768670:CALNI RS07590
gene id: 768670:CALNI_RS07590
uniprot id: E4TEQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

768670:CALNI RS05185
gene id: 768670:CALNI_RS05185
uniprot id: E4TI17
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

768670:CALNI RS01735
gene id: 768670:CALNI_RS01735
uniprot id: E4TK13
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

768670:CALNI RS09370
gene id: 768670:CALNI_RS09370
uniprot id: E4TGP9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

768670:CALNI RS01220
gene id: 768670:CALNI_RS01220
uniprot id: E4TJJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

768670:CALNI RS06180
gene id: 768670:CALNI_RS06180
uniprot id: E4TJ09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

768670:CALNI RS07230
gene id: 768670:CALNI_RS07230
uniprot id: E4TK66
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

768670:CALNI RS00280
gene id: 768670:CALNI_RS00280
uniprot id: E4TIE8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

768670:CALNI RS03730
gene id: 768670:CALNI_RS03730
uniprot id: E4TGH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

768670:CALNI RS06620
gene id: 768670:CALNI_RS06620
uniprot id: E4TJG2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

768670:CALNI RS06010
gene id: 768670:CALNI_RS06010
uniprot id: E4TIX6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

768670:CALNI RS08830
gene id: 768670:CALNI_RS08830
uniprot id: E4TG71
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

768670:CALNI RS06690
gene id: 768670:CALNI_RS06690
uniprot id: E4TJP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

768670:CALNI RS02470
gene id: 768670:CALNI_RS02470
uniprot id: E4TF67
names: Similarity
messages: Belongs to the SfsA family.

768670:CALNI RS02710
gene id: 768670:CALNI_RS02710
uniprot id: E4TFB5
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS10100
gene id: 768670:CALNI_RS10100
uniprot id: E4THF3
names: Similarity
messages: Belongs to the UPF0102 family.

768670:CALNI RS00410
gene id: 768670:CALNI_RS00410
uniprot id: E4TIH4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

768670:CALNI RS08620
gene id: 768670:CALNI_RS08620
uniprot id: E4TFV9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

768670:CALNI RS04635
gene id: 768670:CALNI_RS04635
uniprot id: E4THL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

768670:CALNI RS00910
gene id: 768670:CALNI_RS00910
uniprot id: E4TJ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

768670:CALNI RS01155
gene id: 768670:CALNI_RS01155
uniprot id: E4TJI6
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

768670:CALNI RS07705
gene id: 768670:CALNI_RS07705
uniprot id: E4TEZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

768670:CALNI RS10675
gene id: 768670:CALNI_RS10675
uniprot id: E4TKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

768670:CALNI RS02305
gene id: 768670:CALNI_RS02305
uniprot id: E4TEW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

768670:CALNI RS03685
gene id: 768670:CALNI_RS03685
uniprot id: E4TGG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

768670:CALNI RS01480
gene id: 768670:CALNI_RS01480
uniprot id: E4TJW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

768670:CALNI RS00195
gene id: 768670:CALNI_RS00195
uniprot id: E4TID1
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS10115
gene id: 768670:CALNI_RS10115
uniprot id: E4THF6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

768670:CALNI RS00555
gene id: 768670:CALNI_RS00555
uniprot id: E4TF97
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

768670:CALNI RS01110
gene id: 768670:CALNI_RS01110
uniprot id: E4TJH7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

768670:CALNI RS09635
gene id: 768670:CALNI_RS09635
uniprot id: E4TH15
names: Similarity
messages: Belongs to the UPF0045 family.

768670:CALNI RS01600
gene id: 768670:CALNI_RS01600
uniprot id: E4TJY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

768670:CALNI RS09170
gene id: 768670:CALNI_RS09170
uniprot id: E4TGK9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

768670:CALNI RS02480
gene id: 768670:CALNI_RS02480
uniprot id: E4TF69
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

768670:CALNI RS10285
gene id: 768670:CALNI_RS10285
uniprot id: E4THR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

768670:CALNI RS06855
gene id: 768670:CALNI_RS06855
uniprot id: E4TJS1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

768670:CALNI RS06075
gene id: 768670:CALNI_RS06075
uniprot id: E4TIY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

768670:CALNI RS07680
gene id: 768670:CALNI_RS07680
uniprot id: E4TES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS10015
gene id: 768670:CALNI_RS10015
uniprot id: E4THD9
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS08120
gene id: 768670:CALNI_RS08120
uniprot id: E4TFE4
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

768670:CALNI RS00615
gene id: 768670:CALNI_RS00615
uniprot id: E4TIT4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

768670:CALNI RS06305
gene id: 768670:CALNI_RS06305
uniprot id: E4TJ99
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

768670:CALNI RS02245
gene id: 768670:CALNI_RS02245
uniprot id: E4TEV6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

768670:CALNI RS01765
gene id: 768670:CALNI_RS01765
uniprot id: E4TK19
names: Similarity
messages: Belongs to the UPF0758 family.

768670:CALNI RS08570
gene id: 768670:CALNI_RS08570
uniprot id: E4TFU9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

768670:CALNI RS02080
gene id: 768670:CALNI_RS02080
uniprot id: E4TEK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

768670:CALNI RS05850
gene id: 768670:CALNI_RS05850
uniprot id: E4TIM9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS10030
gene id: 768670:CALNI_RS10030
uniprot id: E4THE0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

768670:CALNI RS00880
gene id: 768670:CALNI_RS00880
uniprot id: E4TJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS04980
gene id: 768670:CALNI_RS04980
uniprot id: E4THX7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS04410
gene id: 768670:CALNI_RS04410
uniprot id: E4TH99
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

768670:CALNI RS03840
gene id: 768670:CALNI_RS03840
uniprot id: E4TGS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

768670:CALNI RS01605
gene id: 768670:CALNI_RS01605
uniprot id: E4TJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

768670:CALNI RS10130
gene id: 768670:CALNI_RS10130
uniprot id: E4THF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

768670:CALNI RS05380
gene id: 768670:CALNI_RS05380
uniprot id: E4TI68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

768670:CALNI RS03720
gene id: 768670:CALNI_RS03720
uniprot id: E4TGH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

768670:CALNI RS08135
gene id: 768670:CALNI_RS08135
uniprot id: E4TFE7
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

768670:CALNI RS08015
gene id: 768670:CALNI_RS08015
uniprot id: E4TF56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

768670:CALNI RS07160
gene id: 768670:CALNI_RS07160
uniprot id: E4TK52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

768670:CALNI RS04350
gene id: 768670:CALNI_RS04350
uniprot id: E4TH87
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

768670:CALNI RS08045
gene id: 768670:CALNI_RS08045
uniprot id: E4TF62
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

768670:CALNI RS07520
gene id: 768670:CALNI_RS07520
uniprot id: E4TEP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

768670:CALNI RS02550
gene id: 768670:CALNI_RS02550
uniprot id: E4TF83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

768670:CALNI RS07405
gene id: 768670:CALNI_RS07405
uniprot id: E4TEM0
names: Similarity
messages: Belongs to the HupF/HypC family.

768670:CALNI RS04240
gene id: 768670:CALNI_RS04240
uniprot id: E4TH65
names: Similarity
messages: Belongs to the serpin family.

768670:CALNI RS00395
gene id: 768670:CALNI_RS00395
uniprot id: E4TIH1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

768670:CALNI RS06985
gene id: 768670:CALNI_RS06985
uniprot id: E4TJU7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS05545
gene id: 768670:CALNI_RS05545
uniprot id: E4TIA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

768670:CALNI RS02425
gene id: 768670:CALNI_RS02425
uniprot id: E4TEZ2
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS01115
gene id: 768670:CALNI_RS01115
uniprot id: E4TJH8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

768670:CALNI RS01470
gene id: 768670:CALNI_RS01470
uniprot id: E4TJV9
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

768670:CALNI RS04995
gene id: 768670:CALNI_RS04995
uniprot id: E4THY0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

768670:CALNI RS03785
gene id: 768670:CALNI_RS03785
uniprot id: E4TGI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS03905
gene id: 768670:CALNI_RS03905
uniprot id: E4TGT3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS05925
gene id: 768670:CALNI_RS05925
uniprot id: E4TIP3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

768670:CALNI RS10410
gene id: 768670:CALNI_RS10410
uniprot id: E4THU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

768670:CALNI RS06775
gene id: 768670:CALNI_RS06775
uniprot id: E4TJQ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

768670:CALNI RS06790
gene id: 768670:CALNI_RS06790
uniprot id: E4TJQ8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

768670:CALNI RS10315
gene id: 768670:CALNI_RS10315
uniprot id: E4THS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

768670:CALNI RS05675
gene id: 768670:CALNI_RS05675
uniprot id: E4TIJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

768670:CALNI RS10125
gene id: 768670:CALNI_RS10125
uniprot id: E4THF8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS01545
gene id: 768670:CALNI_RS01545
uniprot id: E4TJX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

768670:CALNI RS07570
gene id: 768670:CALNI_RS07570
uniprot id: E4TEQ4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

768670:CALNI RS05455
gene id: 768670:CALNI_RS05455
uniprot id: E4TI83
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

768670:CALNI RS07745
gene id: 768670:CALNI_RS07745
uniprot id: E4TF04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

768670:CALNI RS05705
gene id: 768670:CALNI_RS05705
uniprot id: E4TIK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

768670:CALNI RS01455
gene id: 768670:CALNI_RS01455
uniprot id: E4TJV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

768670:CALNI RS03575
gene id: 768670:CALNI_RS03575
uniprot id: E4TGE5
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

768670:CALNI RS02640
gene id: 768670:CALNI_RS02640
uniprot id: E4TFA1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

768670:CALNI RS09825
gene id: 768670:CALNI_RS09825
uniprot id: E4TH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

768670:CALNI RS05360
gene id: 768670:CALNI_RS05360
uniprot id: E4TI64
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

768670:CALNI RS04510
gene id: 768670:CALNI_RS04510
uniprot id: E4THI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

768670:CALNI RS06210
gene id: 768670:CALNI_RS06210
uniprot id: E4TJ15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

768670:CALNI RS00035
gene id: 768670:CALNI_RS00035
uniprot id: E4TI27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

768670:CALNI RS10785
gene id: 768670:CALNI_RS10785
uniprot id: E4TFM2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

768670:CALNI RS04640
gene id: 768670:CALNI_RS04640
uniprot id: E4THL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

768670:CALNI RS05560
gene id: 768670:CALNI_RS05560
uniprot id: E4TIA5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

768670:CALNI RS08500
gene id: 768670:CALNI_RS08500
uniprot id: E4TFT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

768670:CALNI RS06525
gene id: 768670:CALNI_RS06525
uniprot id: E4TJE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

768670:CALNI RS07610
gene id: 768670:CALNI_RS07610
uniprot id: E4TER2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

768670:CALNI RS07670
gene id: 768670:CALNI_RS07670
uniprot id: E4TES3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

768670:CALNI RS02915
gene id: 768670:CALNI_RS02915
uniprot id: E4TFM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

768670:CALNI RS10320
gene id: 768670:CALNI_RS10320
uniprot id: E4THS2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

768670:CALNI RS05425
gene id: 768670:CALNI_RS05425
uniprot id: E4TI77
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

768670:CALNI RS06565
gene id: 768670:CALNI_RS06565
uniprot id: E4TJF1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

768670:CALNI RS01170
gene id: 768670:CALNI_RS01170
uniprot id: E4TJI9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

768670:CALNI RS09325
gene id: 768670:CALNI_RS09325
uniprot id: E4TGP0
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS05635
gene id: 768670:CALNI_RS05635
uniprot id: E4TII8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

768670:CALNI RS00350
gene id: 768670:CALNI_RS00350
uniprot id: E4TIG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

768670:CALNI RS02955
gene id: 768670:CALNI_RS02955
uniprot id: E4TFN5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

768670:CALNI RS07915
gene id: 768670:CALNI_RS07915
uniprot id: E4TF37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

768670:CALNI RS06800
gene id: 768670:CALNI_RS06800
uniprot id: E4TJR1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

768670:CALNI RS06285
gene id: 768670:CALNI_RS06285
uniprot id: E4TJ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

768670:CALNI RS07730
gene id: 768670:CALNI_RS07730
uniprot id: E4TF02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

768670:CALNI RS04970
gene id: 768670:CALNI_RS04970
uniprot id: E4THX5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

768670:CALNI RS08725
gene id: 768670:CALNI_RS08725
uniprot id: E4TFY0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS08140
gene id: 768670:CALNI_RS08140
uniprot id: E4TFE8
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

768670:CALNI RS00885
gene id: 768670:CALNI_RS00885
uniprot id: E4TJ59
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

768670:CALNI RS07635
gene id: 768670:CALNI_RS07635
uniprot id: E4TER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

768670:CALNI RS05660
gene id: 768670:CALNI_RS05660
uniprot id: E4TIJ2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

768670:CALNI RS06090
gene id: 768670:CALNI_RS06090
uniprot id: E4TIZ1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

768670:CALNI RS07245
gene id: 768670:CALNI_RS07245
uniprot id: E4TK69
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS09310
gene id: 768670:CALNI_RS09310
uniprot id: E4TGN7
names: Similarity
messages: Belongs to the pyruvate kinase family.

768670:CALNI RS08255
gene id: 768670:CALNI_RS08255
uniprot id: E4TFG9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

768670:CALNI RS00495
gene id: 768670:CALNI_RS00495
uniprot id: E4TIQ9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

768670:CALNI RS09690
gene id: 768670:CALNI_RS09690
uniprot id: E4TH24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

768670:CALNI RS03635
gene id: 768670:CALNI_RS03635
uniprot id: E4TGF7
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

768670:CALNI RS00845
gene id: 768670:CALNI_RS00845
uniprot id: E4TJ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS07690
gene id: 768670:CALNI_RS07690
uniprot id: E4TES7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

768670:CALNI RS06300
gene id: 768670:CALNI_RS06300
uniprot id: E4TJ98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

768670:CALNI RS02165
gene id: 768670:CALNI_RS02165
uniprot id: E4TEU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

768670:CALNI RS01325
gene id: 768670:CALNI_RS01325
uniprot id: E4TJM0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

768670:CALNI RS02865
gene id: 768670:CALNI_RS02865
uniprot id: E4TFL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

768670:CALNI RS10915
gene id: 768670:CALNI_RS10915
uniprot id: E4TF30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS04535
gene id: 768670:CALNI_RS04535
uniprot id: E4THJ2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

768670:CALNI RS04180
gene id: 768670:CALNI_RS04180
uniprot id: E4TH53
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS09020
gene id: 768670:CALNI_RS09020
uniprot id: E4TGA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

768670:CALNI RS05400
gene id: 768670:CALNI_RS05400
uniprot id: E4TI72
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS10290
gene id: 768670:CALNI_RS10290
uniprot id: E4THR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

768670:CALNI RS03650
gene id: 768670:CALNI_RS03650
uniprot id: E4TGG0
names: Similarity
messages: Belongs to the peptidase M16 family.

768670:CALNI RS01240
gene id: 768670:CALNI_RS01240
uniprot id: E4TJK3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

768670:CALNI RS00680
gene id: 768670:CALNI_RS00680
uniprot id: E4TIU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

768670:CALNI RS08840
gene id: 768670:CALNI_RS08840
uniprot id: E4TG73
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

768670:CALNI RS05470
gene id: 768670:CALNI_RS05470
uniprot id: E4TI86
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

768670:CALNI RS04710
gene id: 768670:CALNI_RS04710
uniprot id: E4THM7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

768670:CALNI RS10090
gene id: 768670:CALNI_RS10090
uniprot id: E4THF1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

768670:CALNI RS09785
gene id: 768670:CALNI_RS09785
uniprot id: E4TH37
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

768670:CALNI RS07640
gene id: 768670:CALNI_RS07640
uniprot id: E4TER9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

768670:CALNI RS04665
gene id: 768670:CALNI_RS04665
uniprot id: E4THL8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

768670:CALNI RS10035
gene id: 768670:CALNI_RS10035
uniprot id: E4THE1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

768670:CALNI RS08010
gene id: 768670:CALNI_RS08010
uniprot id: E4TF55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

768670:CALNI RS02940
gene id: 768670:CALNI_RS02940
uniprot id: E4TFN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

768670:CALNI RS05095
gene id: 768670:CALNI_RS05095
uniprot id: E4THZ9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

768670:CALNI RS08790
gene id: 768670:CALNI_RS08790
uniprot id: E4TG62
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

768670:CALNI RS05110
gene id: 768670:CALNI_RS05110
uniprot id: E4TI02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

768670:CALNI RS01630
gene id: 768670:CALNI_RS01630
uniprot id: E4TJZ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

768670:CALNI RS04545
gene id: 768670:CALNI_RS04545
uniprot id: E4THJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

768670:CALNI RS07565
gene id: 768670:CALNI_RS07565
uniprot id: E4TEQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

768670:CALNI RS08130
gene id: 768670:CALNI_RS08130
uniprot id: E4TFE6
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

768670:CALNI RS10900
gene id: 768670:CALNI_RS10900
uniprot id: E4TJU8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

768670:CALNI RS03455
gene id: 768670:CALNI_RS03455
uniprot id: E4TG52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

768670:CALNI RS01060
gene id: 768670:CALNI_RS01060
uniprot id: E4TJ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

768670:CALNI RS07385
gene id: 768670:CALNI_RS07385
uniprot id: E4TEL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS01550
gene id: 768670:CALNI_RS01550
uniprot id: E4TJX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

768670:CALNI RS05160
gene id: 768670:CALNI_RS05160
uniprot id: E4TI12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

768670:CALNI RS06405
gene id: 768670:CALNI_RS06405
uniprot id: E4TJB9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS00690
gene id: 768670:CALNI_RS00690
uniprot id: E4TIV0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

768670:CALNI RS04800
gene id: 768670:CALNI_RS04800
uniprot id: E4THP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

768670:CALNI RS04915
gene id: 768670:CALNI_RS04915
uniprot id: E4THW4
names: Similarity
messages: Belongs to the TrpA family.

768670:CALNI RS07780
gene id: 768670:CALNI_RS07780
uniprot id: E4TF10
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

768670:CALNI RS05505
gene id: 768670:CALNI_RS05505
uniprot id: E4TI94
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

768670:CALNI RS00085
gene id: 768670:CALNI_RS00085
uniprot id: E4TIA9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

768670:CALNI RS10865
gene id: 768670:CALNI_RS10865
uniprot id: E4TI97
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

768670:CALNI RS05410
gene id: 768670:CALNI_RS05410
uniprot id: E4TI74
names: Similarity
messages: Belongs to the GARS family.

768670:CALNI RS09145
gene id: 768670:CALNI_RS09145
uniprot id: E4TGK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

768670:CALNI RS07035
gene id: 768670:CALNI_RS07035
uniprot id: E4TK27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

768670:CALNI RS05085
gene id: 768670:CALNI_RS05085
uniprot id: E4THZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

768670:CALNI RS00445
gene id: 768670:CALNI_RS00445
uniprot id: E4TIP9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

768670:CALNI RS04220
gene id: 768670:CALNI_RS04220
uniprot id: E4TH61
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS01410
gene id: 768670:CALNI_RS01410
uniprot id: E4TJN7
names: Similarity
messages: Belongs to the acylphosphatase family.

768670:CALNI RS04910
gene id: 768670:CALNI_RS04910
uniprot id: E4THW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

768670:CALNI RS00020
gene id: 768670:CALNI_RS00020
uniprot id: E4TI24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

768670:CALNI RS08325
gene id: 768670:CALNI_RS08325
uniprot id: E4TFI3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS10655
gene id: 768670:CALNI_RS10655
uniprot id: E4TKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS01555
gene id: 768670:CALNI_RS01555
uniprot id: E4TJX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

768670:CALNI RS01810
gene id: 768670:CALNI_RS01810
uniprot id: E4TEF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

768670:CALNI RS01925
gene id: 768670:CALNI_RS01925
uniprot id: E4TEH2
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS02175
gene id: 768670:CALNI_RS02175
uniprot id: E4TEU2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

768670:CALNI RS08000
gene id: 768670:CALNI_RS08000
uniprot id: E4TF53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

768670:CALNI RS08650
gene id: 768670:CALNI_RS08650
uniprot id: E4TFW5
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS03755
gene id: 768670:CALNI_RS03755
uniprot id: E4TGI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

768670:CALNI RS03310
gene id: 768670:CALNI_RS03310
uniprot id: E4TG23
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

768670:CALNI RS06950
gene id: 768670:CALNI_RS06950
uniprot id: E4TJU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

768670:CALNI RS03340
gene id: 768670:CALNI_RS03340
uniprot id: E4TG29
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

768670:CALNI RS06785
gene id: 768670:CALNI_RS06785
uniprot id: E4TJQ7
names: Similarity
messages: Belongs to the UPF0166 family.

768670:CALNI RS01185
gene id: 768670:CALNI_RS01185
uniprot id: E4TJJ2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

768670:CALNI RS05205
gene id: 768670:CALNI_RS05205
uniprot id: E4TI20
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

768670:CALNI RS01695
gene id: 768670:CALNI_RS01695
uniprot id: E4TK05
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

768670:CALNI RS08745
gene id: 768670:CALNI_RS08745
uniprot id: E4TFY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

768670:CALNI RS02900
gene id: 768670:CALNI_RS02900
uniprot id: E4TFM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

768670:CALNI RS01095
gene id: 768670:CALNI_RS01095
uniprot id: E4TJH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

768670:CALNI RS07130
gene id: 768670:CALNI_RS07130
uniprot id: E4TK46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

768670:CALNI RS00465
gene id: 768670:CALNI_RS00465
uniprot id: E4TIQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

768670:CALNI RS06550
gene id: 768670:CALNI_RS06550
uniprot id: E4TJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

768670:CALNI RS10425
gene id: 768670:CALNI_RS10425
uniprot id: E4THU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

768670:CALNI RS04335
gene id: 768670:CALNI_RS04335
uniprot id: E4TH84
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

768670:CALNI RS01005
gene id: 768670:CALNI_RS01005
uniprot id: E4TJ82
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

768670:CALNI RS04895
gene id: 768670:CALNI_RS04895
uniprot id: E4THW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS04810
gene id: 768670:CALNI_RS04810
uniprot id: E4THP7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

768670:CALNI RS04935
gene id: 768670:CALNI_RS04935
uniprot id: E4THW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

768670:CALNI RS08430
gene id: 768670:CALNI_RS08430
uniprot id: E4TFS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

768670:CALNI RS06810
gene id: 768670:CALNI_RS06810
uniprot id: E4TJR3
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS07910
gene id: 768670:CALNI_RS07910
uniprot id: E4TF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS01445
gene id: 768670:CALNI_RS01445
uniprot id: E4TJV4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS04560
gene id: 768670:CALNI_RS04560
uniprot id: E4THJ7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

768670:CALNI RS06095
gene id: 768670:CALNI_RS06095
uniprot id: E4TIZ2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS01175
gene id: 768670:CALNI_RS01175
uniprot id: E4TJJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

768670:CALNI RS09680
gene id: 768670:CALNI_RS09680
uniprot id: E4TG93
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

768670:CALNI RS05600
gene id: 768670:CALNI_RS05600
uniprot id: E4TII1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

768670:CALNI RS02925
gene id: 768670:CALNI_RS02925
uniprot id: E4TFM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

768670:CALNI RS08600
gene id: 768670:CALNI_RS08600
uniprot id: E4TFV5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

768670:CALNI RS09805
gene id: 768670:CALNI_RS09805
uniprot id: E4TH41
names: Similarity
messages: Belongs to the CinA family.

768670:CALNI RS04920
gene id: 768670:CALNI_RS04920
uniprot id: E4THW5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS10960
gene id: 768670:CALNI_RS10960
uniprot id: E4TGB6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

768670:CALNI RS03090
gene id: 768670:CALNI_RS03090
uniprot id: E4TFR0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

768670:CALNI RS06235
gene id: 768670:CALNI_RS06235
uniprot id: E4TJ20
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

768670:CALNI RS08530
gene id: 768670:CALNI_RS08530
uniprot id: E4TFU1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

768670:CALNI RS10145
gene id: 768670:CALNI_RS10145
uniprot id: E4THG2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS10170
gene id: 768670:CALNI_RS10170
uniprot id: E4THG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

768670:CALNI RS00520
gene id: 768670:CALNI_RS00520
uniprot id: E4TIR4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

768670:CALNI RS04940
gene id: 768670:CALNI_RS04940
uniprot id: E4THW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

768670:CALNI RS07695
gene id: 768670:CALNI_RS07695
uniprot id: E4TES8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

768670:CALNI RS08605
gene id: 768670:CALNI_RS08605
uniprot id: E4TFV6
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS03190
gene id: 768670:CALNI_RS03190
uniprot id: E4TFZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

768670:CALNI RS05535
gene id: 768670:CALNI_RS05535
uniprot id: E4TIA0
names: Similarity
messages: Belongs to the DprA/Smf family.

768670:CALNI RS09450
gene id: 768670:CALNI_RS09450
uniprot id: E4TGR4
names: Subcellular Location Annotation
messages: Cytoplasm

768670:CALNI RS05710
gene id: 768670:CALNI_RS05710
uniprot id: E4TIK2
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS01335
gene id: 768670:CALNI_RS01335
uniprot id: E4TJM2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

768670:CALNI RS01830
gene id: 768670:CALNI_RS01830
uniprot id: E4TEF7
names: Similarity
messages: Belongs to the thioredoxin family.

768670:CALNI RS10935
gene id: 768670:CALNI_RS10935
uniprot id: E4TFJ0
names: Similarity
messages: Belongs to the NusB family.

768670:CALNI RS00210
gene id: 768670:CALNI_RS00210
uniprot id: E4TID4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

768670:CALNI RS00485
gene id: 768670:CALNI_RS00485
uniprot id: E4TIQ7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

768670:CALNI RS04475
gene id: 768670:CALNI_RS04475
uniprot id: E4THB1
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS01615
gene id: 768670:CALNI_RS01615
uniprot id: E4TJY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

768670:CALNI RS03810
gene id: 768670:CALNI_RS03810
uniprot id: E4TGJ3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

768670:CALNI RS00835
gene id: 768670:CALNI_RS00835
uniprot id: E4TJ48
names: Similarity
messages: Belongs to the glutamate synthase family.

768670:CALNI RS06230
gene id: 768670:CALNI_RS06230
uniprot id: E4TJ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

768670:CALNI RS04495
gene id: 768670:CALNI_RS04495
uniprot id: E4THI4
names: Subunit
messages: Homodimer.

768670:CALNI RS05895
gene id: 768670:CALNI_RS05895
uniprot id: E4TIN7
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS08510
gene id: 768670:CALNI_RS08510
uniprot id: E4TFT7
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

768670:CALNI RS04610
gene id: 768670:CALNI_RS04610
uniprot id: E4THK7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS06980
gene id: 768670:CALNI_RS06980
uniprot id: E4TJU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

768670:CALNI RS06555
gene id: 768670:CALNI_RS06555
uniprot id: E4TJE9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

768670:CALNI RS05730
gene id: 768670:CALNI_RS05730
uniprot id: E4TIK6
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS05200
gene id: 768670:CALNI_RS05200
uniprot id: E4TI19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

768670:CALNI RS06520
gene id: 768670:CALNI_RS06520
uniprot id: E4TJE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

768670:CALNI RS00135
gene id: 768670:CALNI_RS00135
uniprot id: E4TIB9
names: Subcellular Location Annotation
messages: Cytoplasm

768670:CALNI RS05285
gene id: 768670:CALNI_RS05285
uniprot id: E4TI50
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

768670:CALNI RS08340
gene id: 768670:CALNI_RS08340
uniprot id: E4TFI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

768670:CALNI RS00460
gene id: 768670:CALNI_RS00460
uniprot id: E4TIQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

768670:CALNI RS00820
gene id: 768670:CALNI_RS00820
uniprot id: E4TJ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

768670:CALNI RS00490
gene id: 768670:CALNI_RS00490
uniprot id: E4TIQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

768670:CALNI RS04470
gene id: 768670:CALNI_RS04470
uniprot id: E4THB0
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS06330
gene id: 768670:CALNI_RS06330
uniprot id: E4TJA4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

768670:CALNI RS05995
gene id: 768670:CALNI_RS05995
uniprot id: E4TIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

768670:CALNI RS01490
gene id: 768670:CALNI_RS01490
uniprot id: E4TJW3
names: Similarity
messages: Belongs to the Skp family.

768670:CALNI RS00860
gene id: 768670:CALNI_RS00860
uniprot id: E4TJ53
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS07710
gene id: 768670:CALNI_RS07710
uniprot id: E4TEZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

768670:CALNI RS10600
gene id: 768670:CALNI_RS10600
uniprot id: E4TKB3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

768670:CALNI RS02025
gene id: 768670:CALNI_RS02025
uniprot id: E4TEJ2
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

768670:CALNI RS03600
gene id: 768670:CALNI_RS03600
uniprot id: E4TGF0
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

768670:CALNI RS04215
gene id: 768670:CALNI_RS04215
uniprot id: E4TH60
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS05650
gene id: 768670:CALNI_RS05650
uniprot id: E4TIJ0
names: Similarity
messages: Belongs to the UPF0111 family.

768670:CALNI RS05015
gene id: 768670:CALNI_RS05015
uniprot id: E4THY4
names: Similarity
messages: Belongs to the DEAD box helicase family.

768670:CALNI RS07325
gene id: 768670:CALNI_RS07325
uniprot id: E4TK85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

768670:CALNI RS06600
gene id: 768670:CALNI_RS06600
uniprot id: E4TJF8
names: Similarity
messages: Belongs to the UPF0434 family.

768670:CALNI RS05570
gene id: 768670:CALNI_RS05570
uniprot id: E4TIH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

768670:CALNI RS04460
gene id: 768670:CALNI_RS04460
uniprot id: E4THA8
names: Similarity
messages: Belongs to the leucine-binding protein family.

768670:CALNI RS01235
gene id: 768670:CALNI_RS01235
uniprot id: E4TJK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

768670:CALNI RS01350
gene id: 768670:CALNI_RS01350
uniprot id: E4TJM5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

768670:CALNI RS04355
gene id: 768670:CALNI_RS04355
uniprot id: E4TH88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS04375
gene id: 768670:CALNI_RS04375
uniprot id: E4TH92
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

768670:CALNI RS02660
gene id: 768670:CALNI_RS02660
uniprot id: E4TFA5
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS06900
gene id: 768670:CALNI_RS06900
uniprot id: E4TJT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

768670:CALNI RS03165
gene id: 768670:CALNI_RS03165
uniprot id: E4TFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

768670:CALNI RS03295
gene id: 768670:CALNI_RS03295
uniprot id: E4TG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

768670:CALNI RS00025
gene id: 768670:CALNI_RS00025
uniprot id: E4TI25
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

768670:CALNI RS06185
gene id: 768670:CALNI_RS06185
uniprot id: E4TJ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

768670:CALNI RS07585
gene id: 768670:CALNI_RS07585
uniprot id: E4TEQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

768670:CALNI RS03325
gene id: 768670:CALNI_RS03325
uniprot id: E4TG26
names: Similarity
messages: Belongs to the RecJ family.

768670:CALNI RS07205
gene id: 768670:CALNI_RS07205
uniprot id: E4TK61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

768670:CALNI RS11015
gene id: 768670:CALNI_RS11015
uniprot id: E4TKA9
names: Similarity
messages: Belongs to the ParB family.

768670:CALNI RS00010
gene id: 768670:CALNI_RS00010
uniprot id: E4TI22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

768670:CALNI RS03465
gene id: 768670:CALNI_RS03465
uniprot id: E4TG54
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

768670:CALNI RS01590
gene id: 768670:CALNI_RS01590
uniprot id: E4TJY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

768670:CALNI RS02235
gene id: 768670:CALNI_RS02235
uniprot id: E4TEV4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

768670:CALNI RS00015
gene id: 768670:CALNI_RS00015
uniprot id: E4TI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

768670:CALNI RS00300
gene id: 768670:CALNI_RS00300
uniprot id: E4TIF2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

768670:CALNI RS09045
gene id: 768670:CALNI_RS09045
uniprot id: E4TGB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

768670:CALNI RS02980
gene id: 768670:CALNI_RS02980
uniprot id: E4TFP0
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS10195
gene id: 768670:CALNI_RS10195
uniprot id: E4THH2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

768670:CALNI RS04580
gene id: 768670:CALNI_RS04580
uniprot id: E4THK1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

768670:CALNI RS08855
gene id: 768670:CALNI_RS08855
uniprot id: E4TG76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

768670:CALNI RS05800
gene id: 768670:CALNI_RS05800
uniprot id: E4TIL9
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

768670:CALNI RS03395
gene id: 768670:CALNI_RS03395
uniprot id: E4TG40
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

768670:CALNI RS01680
gene id: 768670:CALNI_RS01680
uniprot id: E4TK02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

768670:CALNI RS02805
gene id: 768670:CALNI_RS02805
uniprot id: E4TFK5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

768670:CALNI RS01045
gene id: 768670:CALNI_RS01045
uniprot id: E4TJ90
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

768670:CALNI RS10700
gene id: 768670:CALNI_RS10700
uniprot id: E4TKD5
names: Similarity
messages: Belongs to the CobH/CbiC family.

768670:CALNI RS04490
gene id: 768670:CALNI_RS04490
uniprot id: E4THI3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

768670:CALNI RS08780
gene id: 768670:CALNI_RS08780
uniprot id: E4TG60
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

768670:CALNI RS07595
gene id: 768670:CALNI_RS07595
uniprot id: E4TEQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

768670:CALNI RS04515
gene id: 768670:CALNI_RS04515
uniprot id: E4THI8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

768670:CALNI RS10575
gene id: 768670:CALNI_RS10575
uniprot id: E4TKA8
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

768670:CALNI RS08575
gene id: 768670:CALNI_RS08575
uniprot id: E4TFV0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

768670:CALNI RS06645
gene id: 768670:CALNI_RS06645
uniprot id: E4TJG7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

768670:CALNI RS09695
gene id: 768670:CALNI_RS09695
uniprot id: E4TH25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

768670:CALNI RS00685
gene id: 768670:CALNI_RS00685
uniprot id: E4TIU8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

768670:CALNI RS09015
gene id: 768670:CALNI_RS09015
uniprot id: E4TGA4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

768670:CALNI RS09520
gene id: 768670:CALNI_RS09520
uniprot id: E4TGZ3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

768670:CALNI RS04185
gene id: 768670:CALNI_RS04185
uniprot id: E4TH54
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

768670:CALNI RS08975
gene id: 768670:CALNI_RS08975
uniprot id: E4TG96
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

768670:CALNI RS09755
gene id: 768670:CALNI_RS09755
uniprot id: E4TH36
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS05485
gene id: 768670:CALNI_RS05485
uniprot id: E4TI90
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

768670:CALNI RS02390
gene id: 768670:CALNI_RS02390
uniprot id: E4TEY5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS06120
gene id: 768670:CALNI_RS06120
uniprot id: E4TIZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

768670:CALNI RS04595
gene id: 768670:CALNI_RS04595
uniprot id: E4THK4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

768670:CALNI RS04520
gene id: 768670:CALNI_RS04520
uniprot id: E4THI9
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

768670:CALNI RS07515
gene id: 768670:CALNI_RS07515
uniprot id: E4TEP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

768670:CALNI RS01090
gene id: 768670:CALNI_RS01090
uniprot id: E4TJH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

768670:CALNI RS00440
gene id: 768670:CALNI_RS00440
uniprot id: E4TIP8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

768670:CALNI RS00240
gene id: 768670:CALNI_RS00240
uniprot id: E4TIE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS07600
gene id: 768670:CALNI_RS07600
uniprot id: E4TER0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

768670:CALNI RS01585
gene id: 768670:CALNI_RS01585
uniprot id: E4TJY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

768670:CALNI RS04025
gene id: 768670:CALNI_RS04025
uniprot id: E4TGV5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

768670:CALNI RS07360
gene id: 768670:CALNI_RS07360
uniprot id: E4TEL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

768670:CALNI RS08280
gene id: 768670:CALNI_RS08280
uniprot id: E4TFH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

768670:CALNI RS05075
gene id: 768670:CALNI_RS05075
uniprot id: E4THZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS00310
gene id: 768670:CALNI_RS00310
uniprot id: E4TIF4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

768670:CALNI RS02830
gene id: 768670:CALNI_RS02830
uniprot id: E4TFL0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

768670:CALNI RS09060
gene id: 768670:CALNI_RS09060
uniprot id: E4TGB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

768670:CALNI RS07290
gene id: 768670:CALNI_RS07290
uniprot id: E4TK78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

768670:CALNI RS08320
gene id: 768670:CALNI_RS08320
uniprot id: E4TFI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

768670:CALNI RS05355
gene id: 768670:CALNI_RS05355
uniprot id: E4TI63
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

768670:CALNI RS08555
gene id: 768670:CALNI_RS08555
uniprot id: E4TFU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

768670:CALNI RS04660
gene id: 768670:CALNI_RS04660
uniprot id: E4THL7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

768670:CALNI RS05755
gene id: 768670:CALNI_RS05755
uniprot id: E4TIL1
names: Similarity
messages: Belongs to the glycosyltransferase 6 family.

768670:CALNI RS05290
gene id: 768670:CALNI_RS05290
uniprot id: E4TI51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

768670:CALNI RS10890
gene id: 768670:CALNI_RS10890
uniprot id: E4TJC0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

768670:CALNI RS06295
gene id: 768670:CALNI_RS06295
uniprot id: E4TJ97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS09050
gene id: 768670:CALNI_RS09050
uniprot id: E4TGB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

768670:CALNI RS09000
gene id: 768670:CALNI_RS09000
uniprot id: E4TGA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS07085
gene id: 768670:CALNI_RS07085
uniprot id: E4TK37
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

768670:CALNI RS02810
gene id: 768670:CALNI_RS02810
uniprot id: E4TFK6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

768670:CALNI RS02600
gene id: 768670:CALNI_RS02600
uniprot id: E4TF93
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS03335
gene id: 768670:CALNI_RS03335
uniprot id: E4TG28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

768670:CALNI RS10165
gene id: 768670:CALNI_RS10165
uniprot id: E4THG6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

768670:CALNI RS05225
gene id: 768670:CALNI_RS05225
uniprot id: E4TI38
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

768670:CALNI RS04830
gene id: 768670:CALNI_RS04830
uniprot id: E4THQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

768670:CALNI RS09525
gene id: 768670:CALNI_RS09525
uniprot id: E4TGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

768670:CALNI RS07720
gene id: 768670:CALNI_RS07720
uniprot id: E4TF00
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

768670:CALNI RS02375
gene id: 768670:CALNI_RS02375
uniprot id: E4TEY2
names: Similarity
messages: Belongs to the ribF family.

768670:CALNI RS03545
gene id: 768670:CALNI_RS03545
uniprot id: E4TGD9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

768670:CALNI RS02935
gene id: 768670:CALNI_RS02935
uniprot id: E4TFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

768670:CALNI RS01305
gene id: 768670:CALNI_RS01305
uniprot id: E4TJL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

768670:CALNI RS08400
gene id: 768670:CALNI_RS08400
uniprot id: E4TFJ8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

768670:CALNI RS05490
gene id: 768670:CALNI_RS05490
uniprot id: E4TI91
names: Similarity
messages: Belongs to the ycf81 family.

768670:CALNI RS05955
gene id: 768670:CALNI_RS05955
uniprot id: E4TIW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

768670:CALNI RS00855
gene id: 768670:CALNI_RS00855
uniprot id: E4TJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS07235
gene id: 768670:CALNI_RS07235
uniprot id: E4TK67
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

768670:CALNI RS03375
gene id: 768670:CALNI_RS03375
uniprot id: E4TG36
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

768670:CALNI RS01595
gene id: 768670:CALNI_RS01595
uniprot id: E4TJY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

768670:CALNI RS01930
gene id: 768670:CALNI_RS01930
uniprot id: E4TEH3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

768670:CALNI RS07485
gene id: 768670:CALNI_RS07485
uniprot id: E4TEN7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

768670:CALNI RS10755
gene id: 768670:CALNI_RS10755
uniprot id: E4TJ78
names: Similarity
messages: Belongs to the ketopantoate reductase family.

768670:CALNI RS08455
gene id: 768670:CALNI_RS08455
uniprot id: E4TFS6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS04160
gene id: 768670:CALNI_RS04160
uniprot id: E4TGY3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

768670:CALNI RS04790
gene id: 768670:CALNI_RS04790
uniprot id: E4THP3
names: Similarity
messages: Belongs to the hemerythrin family.

768670:CALNI RS05550
gene id: 768670:CALNI_RS05550
uniprot id: E4TIA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

768670:CALNI RS05670
gene id: 768670:CALNI_RS05670
uniprot id: E4TIJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

768670:CALNI RS05695
gene id: 768670:CALNI_RS05695
uniprot id: E4TIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

768670:CALNI RS06080
gene id: 768670:CALNI_RS06080
uniprot id: E4TIY9
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS03820
gene id: 768670:CALNI_RS03820
uniprot id: E4TGJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

768670:CALNI RS01365
gene id: 768670:CALNI_RS01365
uniprot id: E4TJM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS08260
gene id: 768670:CALNI_RS08260
uniprot id: E4TFH0
names: Similarity
messages: Belongs to the MEMO1 family.

768670:CALNI RS04175
gene id: 768670:CALNI_RS04175
uniprot id: E4TH52
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS03045
gene id: 768670:CALNI_RS03045
uniprot id: E4TFQ1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

768670:CALNI RS10435
gene id: 768670:CALNI_RS10435
uniprot id: E4THU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

768670:CALNI RS05655
gene id: 768670:CALNI_RS05655
uniprot id: E4TIJ1
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS07050
gene id: 768670:CALNI_RS07050
uniprot id: E4TK30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

768670:CALNI RS08075
gene id: 768670:CALNI_RS08075
uniprot id: E4TFD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

768670:CALNI RS09950
gene id: 768670:CALNI_RS09950
uniprot id: E4THC5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

768670:CALNI RS01295
gene id: 768670:CALNI_RS01295
uniprot id: E4TJL4
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS05920
gene id: 768670:CALNI_RS05920
uniprot id: E4TIP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

768670:CALNI RS04095
gene id: 768670:CALNI_RS04095
uniprot id: E4TGW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

768670:CALNI RS09205
gene id: 768670:CALNI_RS09205
uniprot id: E4TGL6
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS00525
gene id: 768670:CALNI_RS00525
uniprot id: E4TIR5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

768670:CALNI RS00245
gene id: 768670:CALNI_RS00245
uniprot id: E4TIE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

768670:CALNI RS02030
gene id: 768670:CALNI_RS02030
uniprot id: E4TEJ3
names: Similarity
messages: Belongs to the GSP E family.

768670:CALNI RS07240
gene id: 768670:CALNI_RS07240
uniprot id: E4TK68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

768670:CALNI RS02315
gene id: 768670:CALNI_RS02315
uniprot id: E4TEX0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

768670:CALNI RS00500
gene id: 768670:CALNI_RS00500
uniprot id: E4TIR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

768670:CALNI RS01570
gene id: 768670:CALNI_RS01570
uniprot id: E4TJX9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

768670:CALNI RS07845
gene id: 768670:CALNI_RS07845
uniprot id: E4TF23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

768670:CALNI RS00405
gene id: 768670:CALNI_RS00405
uniprot id: E4TIH3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

768670:CALNI RS09140
gene id: 768670:CALNI_RS09140
uniprot id: E4TGK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

768670:CALNI RS01845
gene id: 768670:CALNI_RS01845
uniprot id: E4TEG0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

768670:CALNI RS03485
gene id: 768670:CALNI_RS03485
uniprot id: E4TGC7
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS02380
gene id: 768670:CALNI_RS02380
uniprot id: E4TEY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

768670:CALNI RS04345
gene id: 768670:CALNI_RS04345
uniprot id: E4TH86
names: Similarity
messages: Belongs to the aspartokinase family.

768670:CALNI RS06500
gene id: 768670:CALNI_RS06500
uniprot id: E4TJD8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

768670:CALNI RS09820
gene id: 768670:CALNI_RS09820
uniprot id: E4TH44
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

768670:CALNI RS07605
gene id: 768670:CALNI_RS07605
uniprot id: E4TER1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

768670:CALNI RS10140
gene id: 768670:CALNI_RS10140
uniprot id: E4THG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

768670:CALNI RS07455
gene id: 768670:CALNI_RS07455
uniprot id: E4TEN0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

768670:CALNI RS03895
gene id: 768670:CALNI_RS03895
uniprot id: E4TGT1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

768670:CALNI RS07470
gene id: 768670:CALNI_RS07470
uniprot id: E4TEN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

768670:CALNI RS08675
gene id: 768670:CALNI_RS08675
uniprot id: E4TFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

768670:CALNI RS01900
gene id: 768670:CALNI_RS01900
uniprot id: E4TEG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

768670:CALNI RS00620
gene id: 768670:CALNI_RS00620
uniprot id: E4TIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

768670:CALNI RS03320
gene id: 768670:CALNI_RS03320
uniprot id: E4TG25
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

768670:CALNI RS00630
gene id: 768670:CALNI_RS00630
uniprot id: E4TIT7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

768670:CALNI RS00230
gene id: 768670:CALNI_RS00230
uniprot id: E4TID8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

768670:CALNI RS06400
gene id: 768670:CALNI_RS06400
uniprot id: E4TJB8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

768670:CALNI RS08950
gene id: 768670:CALNI_RS08950
uniprot id: E4TG91
names: Similarity
messages: Belongs to the UbiD family.

768670:CALNI RS07490
gene id: 768670:CALNI_RS07490
uniprot id: E4TEN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

768670:CALNI RS07495
gene id: 768670:CALNI_RS07495
uniprot id: E4TEN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

768670:CALNI RS02965
gene id: 768670:CALNI_RS02965
uniprot id: E4TFN7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

768670:CALNI RS06675
gene id: 768670:CALNI_RS06675
uniprot id: E4TJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

768670:CALNI RS01915
gene id: 768670:CALNI_RS01915
uniprot id: E4TEH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

768670:CALNI RS08285
gene id: 768670:CALNI_RS08285
uniprot id: E4TFH5
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

768670:CALNI RS05840
gene id: 768670:CALNI_RS05840
uniprot id: E4TIM7
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

768670:CALNI RS02960
gene id: 768670:CALNI_RS02960
uniprot id: E4TFN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS08170
gene id: 768670:CALNI_RS08170
uniprot id: E4TFF2
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

768670:CALNI RS07335
gene id: 768670:CALNI_RS07335
uniprot id: E4TK87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

768670:CALNI RS10300
gene id: 768670:CALNI_RS10300
uniprot id: E4THR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

768670:CALNI RS09985
gene id: 768670:CALNI_RS09985
uniprot id: E4TG93
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

768670:CALNI RS09105
gene id: 768670:CALNI_RS09105
uniprot id: E4TGC2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

768670:CALNI RS06625
gene id: 768670:CALNI_RS06625
uniprot id: E4TJG3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

768670:CALNI RS07460
gene id: 768670:CALNI_RS07460
uniprot id: E4TEN1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

768670:CALNI RS00915
gene id: 768670:CALNI_RS00915
uniprot id: E4TJ65
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

768670:CALNI RS03850
gene id: 768670:CALNI_RS03850
uniprot id: E4TGS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

768670:CALNI RS03385
gene id: 768670:CALNI_RS03385
uniprot id: E4TG38
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

768670:CALNI RS06480
gene id: 768670:CALNI_RS06480
uniprot id: E4TJD4
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS06530
gene id: 768670:CALNI_RS06530
uniprot id: E4TJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

768670:CALNI RS00470
gene id: 768670:CALNI_RS00470
uniprot id: E4TIQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

768670:CALNI RS07885
gene id: 768670:CALNI_RS07885
uniprot id: E4TF31
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

768670:CALNI RS04865
gene id: 768670:CALNI_RS04865
uniprot id: E4THV4
names: Similarity
messages: Belongs to the peptidase S41A family.

768670:CALNI RS01855
gene id: 768670:CALNI_RS01855
uniprot id: E4TEG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

768670:CALNI RS02910
gene id: 768670:CALNI_RS02910
uniprot id: E4TFM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

768670:CALNI RS10355
gene id: 768670:CALNI_RS10355
uniprot id: E4THT1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

768670:CALNI RS02540
gene id: 768670:CALNI_RS02540
uniprot id: E4TF81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

768670:CALNI RS10295
gene id: 768670:CALNI_RS10295
uniprot id: E4THR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

768670:CALNI RS05145
gene id: 768670:CALNI_RS05145
uniprot id: E4TI09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

768670:CALNI RS10510
gene id: 768670:CALNI_RS10510
uniprot id: E4TK97
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

768670:CALNI RS03095
gene id: 768670:CALNI_RS03095
uniprot id: E4TFR1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

768670:CALNI RS04155
gene id: 768670:CALNI_RS04155
uniprot id: E4TGY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

768670:CALNI RS04360
gene id: 768670:CALNI_RS04360
uniprot id: E4TH89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS08335
gene id: 768670:CALNI_RS08335
uniprot id: E4TFI5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

768670:CALNI RS01255
gene id: 768670:CALNI_RS01255
uniprot id: E4TJK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

768670:CALNI RS10190
gene id: 768670:CALNI_RS10190
uniprot id: E4THH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

768670:CALNI RS07115
gene id: 768670:CALNI_RS07115
uniprot id: E4TK43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

768670:CALNI RS06440
gene id: 768670:CALNI_RS06440
uniprot id: E4TJC6
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS01820
gene id: 768670:CALNI_RS01820
uniprot id: E4TEF5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

768670:CALNI RS10040
gene id: 768670:CALNI_RS10040
uniprot id: E4THE2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

768670:CALNI RS03680
gene id: 768670:CALNI_RS03680
uniprot id: E4TGG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

768670:CALNI RS08025
gene id: 768670:CALNI_RS08025
uniprot id: E4TF58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

768670:CALNI RS03275
gene id: 768670:CALNI_RS03275
uniprot id: E4TG16
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

768670:CALNI RS06125
gene id: 768670:CALNI_RS06125
uniprot id: E4TIZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

768670:CALNI RS07080
gene id: 768670:CALNI_RS07080
uniprot id: E4TK36
names: Similarity
messages: Belongs to the argonaute family. Long pAgo subfamily.

768670:CALNI RS08625
gene id: 768670:CALNI_RS08625
uniprot id: E4TFW0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

768670:CALNI RS03145
gene id: 768670:CALNI_RS03145
uniprot id: E4TFY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

768670:CALNI RS08680
gene id: 768670:CALNI_RS08680
uniprot id: E4TFX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

768670:CALNI RS07300
gene id: 768670:CALNI_RS07300
uniprot id: E4TK80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

768670:CALNI RS06135
gene id: 768670:CALNI_RS06135
uniprot id: E4TJ00
names: Similarity
messages: Belongs to the fabD family.

768670:CALNI RS03355
gene id: 768670:CALNI_RS03355
uniprot id: E4TG32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

768670:CALNI RS02365
gene id: 768670:CALNI_RS02365
uniprot id: E4TEY0
names: Similarity
messages: Belongs to the peptidase C40 family.

768670:CALNI RS09510
gene id: 768670:CALNI_RS09510
uniprot id: E4TGZ1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

768670:CALNI RS00545
gene id: 768670:CALNI_RS00545
uniprot id: E4TIR9
names: Subcellular Location Annotation
messages: Cytoplasm

768670:CALNI RS03080
gene id: 768670:CALNI_RS03080
uniprot id: E4TFQ8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

768670:CALNI RS09660
gene id: 768670:CALNI_RS09660
uniprot id: E4TH20
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

768670:CALNI RS01760
gene id: 768670:CALNI_RS01760
uniprot id: E4TK18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

768670:CALNI RS01950
gene id: 768670:CALNI_RS01950
uniprot id: E4TEH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS05265
gene id: 768670:CALNI_RS05265
uniprot id: E4TI46
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

768670:CALNI RS01360
gene id: 768670:CALNI_RS01360
uniprot id: E4TJM7
names: Similarity
messages: Belongs to the TlyA family.

768670:CALNI RS07700
gene id: 768670:CALNI_RS07700
uniprot id: E4TES9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

768670:CALNI RS10160
gene id: 768670:CALNI_RS10160
uniprot id: E4THG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

768670:CALNI RS05930
gene id: 768670:CALNI_RS05930
uniprot id: E4TIP4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

768670:CALNI RS07435
gene id: 768670:CALNI_RS07435
uniprot id: E4TEM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS09480
gene id: 768670:CALNI_RS09480
uniprot id: E4TGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

768670:CALNI RS00655
gene id: 768670:CALNI_RS00655
uniprot id: E4TIU2
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS09800
gene id: 768670:CALNI_RS09800
uniprot id: E4TH40
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

768670:CALNI RS08495
gene id: 768670:CALNI_RS08495
uniprot id: E4TFT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

768670:CALNI RS07250
gene id: 768670:CALNI_RS07250
uniprot id: E4TK70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

768670:CALNI RS04300
gene id: 768670:CALNI_RS04300
uniprot id: E4TH77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS06190
gene id: 768670:CALNI_RS06190
uniprot id: E4TJ11
names: Similarity
messages: Belongs to the UPF0234 family.

768670:CALNI RS10120
gene id: 768670:CALNI_RS10120
uniprot id: E4THF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

768670:CALNI RS05450
gene id: 768670:CALNI_RS05450
uniprot id: E4TI82
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

768670:CALNI RS10330
gene id: 768670:CALNI_RS10330
uniprot id: E4THS5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

768670:CALNI RS01465
gene id: 768670:CALNI_RS01465
uniprot id: E4TJV8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

768670:CALNI RS02775
gene id: 768670:CALNI_RS02775
uniprot id: E4TFC8
names: Similarity
messages: Belongs to the peptidase A31 family.

768670:CALNI RS00005
gene id: 768670:CALNI_RS00005
uniprot id: E4TI21
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

768670:CALNI RS10095
gene id: 768670:CALNI_RS10095
uniprot id: E4THF2
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS09630
gene id: 768670:CALNI_RS09630
uniprot id: E4TH14
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

768670:CALNI RS01020
gene id: 768670:CALNI_RS01020
uniprot id: E4TJ85
names: Similarity
messages: Belongs to the peptidase S49 family.

768670:CALNI RS07945
gene id: 768670:CALNI_RS07945
uniprot id: E4TF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

768670:CALNI RS08755
gene id: 768670:CALNI_RS08755
uniprot id: E4TFY6
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS03865
gene id: 768670:CALNI_RS03865
uniprot id: E4TGS5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

768670:CALNI RS05500
gene id: 768670:CALNI_RS05500
uniprot id: E4TI93
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

768670:CALNI RS06225
gene id: 768670:CALNI_RS06225
uniprot id: E4TJ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

768670:CALNI RS10695
gene id: 768670:CALNI_RS10695
uniprot id: E4TKD4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

768670:CALNI RS01745
gene id: 768670:CALNI_RS01745
uniprot id: E4TK15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

768670:CALNI RS10200
gene id: 768670:CALNI_RS10200
uniprot id: E4THH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

768670:CALNI RS01055
gene id: 768670:CALNI_RS01055
uniprot id: E4TJ92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

768670:CALNI RS07815
gene id: 768670:CALNI_RS07815
uniprot id: E4TF17
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

768670:CALNI RS06670
gene id: 768670:CALNI_RS06670
uniprot id: E4TJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

768670:CALNI RS07740
gene id: 768670:CALNI_RS07740
uniprot id: E4TF03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

768670:CALNI RS06515
gene id: 768670:CALNI_RS06515
uniprot id: E4TJE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

768670:CALNI RS04450
gene id: 768670:CALNI_RS04450
uniprot id: E4THA6
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

768670:CALNI RS03480
gene id: 768670:CALNI_RS03480
uniprot id: E4TGC6
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS02650
gene id: 768670:CALNI_RS02650
uniprot id: E4TFA3
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS10855
gene id: 768670:CALNI_RS10855
uniprot id: E4THW2
names: Similarity
messages: Belongs to the TrpF family.

768670:CALNI RS09885
gene id: 768670:CALNI_RS09885
uniprot id: E4THB6
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS05790
gene id: 768670:CALNI_RS05790
uniprot id: E4TIL7
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS00570
gene id: 768670:CALNI_RS00570
uniprot id: E4TIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS03160
gene id: 768670:CALNI_RS03160
uniprot id: E4TFZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

768670:CALNI RS06640
gene id: 768670:CALNI_RS06640
uniprot id: E4TJG6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

768670:CALNI RS01795
gene id: 768670:CALNI_RS01795
uniprot id: E4TEF0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

768670:CALNI RS05900
gene id: 768670:CALNI_RS05900
uniprot id: E4TIN8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

768670:CALNI RS02460
gene id: 768670:CALNI_RS02460
uniprot id: E4TF65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

768670:CALNI RS04390
gene id: 768670:CALNI_RS04390
uniprot id: E4TH95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

768670:CALNI RS10350
gene id: 768670:CALNI_RS10350
uniprot id: E4THT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

768670:CALNI RS03500
gene id: 768670:CALNI_RS03500
uniprot id: E4TGD0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

768670:CALNI RS06150
gene id: 768670:CALNI_RS06150
uniprot id: E4TJ03
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

768670:CALNI RS02670
gene id: 768670:CALNI_RS02670
uniprot id: E4TFA7
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS06920
gene id: 768670:CALNI_RS06920
uniprot id: E4TJT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

768670:CALNI RS08770
gene id: 768670:CALNI_RS08770
uniprot id: E4TG58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

768670:CALNI RS06825
gene id: 768670:CALNI_RS06825
uniprot id: E4TJR6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

768670:CALNI RS07810
gene id: 768670:CALNI_RS07810
uniprot id: E4TF16
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

768670:CALNI RS08765
gene id: 768670:CALNI_RS08765
uniprot id: E4TG57
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS00670
gene id: 768670:CALNI_RS00670
uniprot id: E4TIU5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS07890
gene id: 768670:CALNI_RS07890
uniprot id: E4TF32
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

768670:CALNI RS04825
gene id: 768670:CALNI_RS04825
uniprot id: E4THQ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

768670:CALNI RS01385
gene id: 768670:CALNI_RS01385
uniprot id: E4TJN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS03155
gene id: 768670:CALNI_RS03155
uniprot id: E4TFZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

768670:CALNI RS08955
gene id: 768670:CALNI_RS08955
uniprot id: E4TG92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

768670:CALNI RS00640
gene id: 768670:CALNI_RS00640
uniprot id: E4TIT9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

768670:CALNI RS04540
gene id: 768670:CALNI_RS04540
uniprot id: E4THJ3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

768670:CALNI RS01645
gene id: 768670:CALNI_RS01645
uniprot id: E4TJZ5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

768670:CALNI RS02985
gene id: 768670:CALNI_RS02985
uniprot id: E4TFP1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS01290
gene id: 768670:CALNI_RS01290
uniprot id: E4TJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

768670:CALNI RS06685
gene id: 768670:CALNI_RS06685
uniprot id: E4TJP6
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

768670:CALNI RS04125
gene id: 768670:CALNI_RS04125
uniprot id: E4TGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

768670:CALNI RS01150
gene id: 768670:CALNI_RS01150
uniprot id: E4TJI5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

768670:CALNI RS04815
gene id: 768670:CALNI_RS04815
uniprot id: E4THP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

768670:CALNI RS04305
gene id: 768670:CALNI_RS04305
uniprot id: E4TH78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS01840
gene id: 768670:CALNI_RS01840
uniprot id: E4TEF9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

768670:CALNI RS02745
gene id: 768670:CALNI_RS02745
uniprot id: E4TFC2
names: Caution
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS08850
gene id: 768670:CALNI_RS08850
uniprot id: E4TG75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS04625
gene id: 768670:CALNI_RS04625
uniprot id: E4THL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

768670:CALNI RS00810
gene id: 768670:CALNI_RS00810
uniprot id: E4TJ43
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

768670:CALNI RS06860
gene id: 768670:CALNI_RS06860
uniprot id: E4TJS2
names: Similarity
messages: Belongs to the peptidase C40 family.

768670:CALNI RS05350
gene id: 768670:CALNI_RS05350
uniprot id: E4TI62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

768670:CALNI RS03735
gene id: 768670:CALNI_RS03735
uniprot id: E4TGH8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS01180
gene id: 768670:CALNI_RS01180
uniprot id: E4TJJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

768670:CALNI RS06495
gene id: 768670:CALNI_RS06495
uniprot id: E4TJD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

768670:CALNI RS06205
gene id: 768670:CALNI_RS06205
uniprot id: E4TJ14
names: Similarity
messages: Belongs to the threonine synthase family.

768670:CALNI RS05235
gene id: 768670:CALNI_RS05235
uniprot id: E4TI40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

768670:CALNI RS07575
gene id: 768670:CALNI_RS07575
uniprot id: E4TEQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

768670:CALNI RS01500
gene id: 768670:CALNI_RS01500
uniprot id: E4TJW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

768670:CALNI RS06345
gene id: 768670:CALNI_RS06345
uniprot id: E4TJA7
names: Cofactor
names: Similarity
messages: Belongs to the cytochrome b560 family.
messages: The heme is bound between the two transmembrane subunits.

768670:CALNI RS03770
gene id: 768670:CALNI_RS03770
uniprot id: E4TGI5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

768670:CALNI RS03170
gene id: 768670:CALNI_RS03170
uniprot id: E4TFZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

768670:CALNI RS07540
gene id: 768670:CALNI_RS07540
uniprot id: E4TEP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

768670:CALNI RS04225
gene id: 768670:CALNI_RS04225
uniprot id: E4TH62
names: Similarity
messages: Belongs to the universal stress protein A family.

768670:CALNI RS08710
gene id: 768670:CALNI_RS08710
uniprot id: E4TFX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

768670:CALNI RS02370
gene id: 768670:CALNI_RS02370
uniprot id: E4TEY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

768670:CALNI RS05680
gene id: 768670:CALNI_RS05680
uniprot id: E4TIJ6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

768670:CALNI RS01145
gene id: 768670:CALNI_RS01145
uniprot id: E4TJI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

768670:CALNI RS06100
gene id: 768670:CALNI_RS06100
uniprot id: E4TIZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

768670:CALNI RS08245
gene id: 768670:CALNI_RS08245
uniprot id: E4TFG7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

768670:CALNI RS01475
gene id: 768670:CALNI_RS01475
uniprot id: E4TJW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS04145
gene id: 768670:CALNI_RS04145
uniprot id: E4TGY0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS05525
gene id: 768670:CALNI_RS05525
uniprot id: E4TI98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

768670:CALNI RS09845
gene id: 768670:CALNI_RS09845
uniprot id: E4TH49
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

768670:CALNI RS10380
gene id: 768670:CALNI_RS10380
uniprot id: E4THT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

768670:CALNI RS09580
gene id: 768670:CALNI_RS09580
uniprot id: E4TH05
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

768670:CALNI RS07340
gene id: 768670:CALNI_RS07340
uniprot id: E4TK88
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

768670:CALNI RS09200
gene id: 768670:CALNI_RS09200
uniprot id: E4TGL5
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS06930
gene id: 768670:CALNI_RS06930
uniprot id: E4TJT6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

768670:CALNI RS08035
gene id: 768670:CALNI_RS08035
uniprot id: E4TF60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

768670:CALNI RS02785
gene id: 768670:CALNI_RS02785
uniprot id: E4TFD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

768670:CALNI RS02675
gene id: 768670:CALNI_RS02675
uniprot id: E4TFA8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

768670:CALNI RS10710
gene id: 768670:CALNI_RS10710
uniprot id: E4TKD7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

768670:CALNI RS05575
gene id: 768670:CALNI_RS05575
uniprot id: E4TIH6
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

768670:CALNI RS03380
gene id: 768670:CALNI_RS03380
uniprot id: E4TG37
names: Similarity
messages: Belongs to the NifZ family.

768670:CALNI RS09840
gene id: 768670:CALNI_RS09840
uniprot id: E4TH48
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

768670:CALNI RS00990
gene id: 768670:CALNI_RS00990
uniprot id: E4TJ79
names: Similarity
messages: Belongs to the ClpA/ClpB family.

768670:CALNI RS03530
gene id: 768670:CALNI_RS03530
uniprot id: E4TGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

768670:CALNI RS08065
gene id: 768670:CALNI_RS08065
uniprot id: E4TFD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

768670:CALNI RS07260
gene id: 768670:CALNI_RS07260
uniprot id: E4TK72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

768670:CALNI RS08370
gene id: 768670:CALNI_RS08370
uniprot id: E4TFJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS02345
gene id: 768670:CALNI_RS02345
uniprot id: E4TEX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

768670:CALNI RS09195
gene id: 768670:CALNI_RS09195
uniprot id: E4TGL4
names: Similarity
messages: Belongs to the leucine-binding protein family.

768670:CALNI RS08005
gene id: 768670:CALNI_RS08005
uniprot id: E4TF54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

768670:CALNI RS05940
gene id: 768670:CALNI_RS05940
uniprot id: E4TIW1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

768670:CALNI RS08705
gene id: 768670:CALNI_RS08705
uniprot id: E4TFX6
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS06570
gene id: 768670:CALNI_RS06570
uniprot id: E4TJF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

768670:CALNI RS04845
gene id: 768670:CALNI_RS04845
uniprot id: E4THQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

768670:CALNI RS10155
gene id: 768670:CALNI_RS10155
uniprot id: E4THG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

768670:CALNI RS02945
gene id: 768670:CALNI_RS02945
uniprot id: E4TFN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

768670:CALNI RS00110
gene id: 768670:CALNI_RS00110
uniprot id: E4TIB4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

768670:CALNI RS09560
gene id: 768670:CALNI_RS09560
uniprot id: E4TH01
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

768670:CALNI RS05945
gene id: 768670:CALNI_RS05945
uniprot id: E4TIW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

768670:CALNI RS07355
gene id: 768670:CALNI_RS07355
uniprot id: E4TEL0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

768670:CALNI RS01780
gene id: 768670:CALNI_RS01780
uniprot id: E4TEE7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS05370
gene id: 768670:CALNI_RS05370
uniprot id: E4TI66
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

768670:CALNI RS04785
gene id: 768670:CALNI_RS04785
uniprot id: E4THP2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

768670:CALNI RS02530
gene id: 768670:CALNI_RS02530
uniprot id: E4TF79
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS04310
gene id: 768670:CALNI_RS04310
uniprot id: E4TH79
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

768670:CALNI RS08945
gene id: 768670:CALNI_RS08945
uniprot id: E4TG90
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

768670:CALNI RS09830
gene id: 768670:CALNI_RS09830
uniprot id: E4TH46
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS05210
gene id: 768670:CALNI_RS05210
uniprot id: E4TI35
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

768670:CALNI RS03880
gene id: 768670:CALNI_RS03880
uniprot id: E4TGS8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

768670:CALNI RS08820
gene id: 768670:CALNI_RS08820
uniprot id: E4TG69
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

768670:CALNI RS03705
gene id: 768670:CALNI_RS03705
uniprot id: E4TGH1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

768670:CALNI RS02145
gene id: 768670:CALNI_RS02145
uniprot id: E4TET7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

768670:CALNI RS03795
gene id: 768670:CALNI_RS03795
uniprot id: E4TGJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

768670:CALNI RS09605
gene id: 768670:CALNI_RS09605
uniprot id: E4TH10
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

768670:CALNI RS01210
gene id: 768670:CALNI_RS01210
uniprot id: E4TJJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

768670:CALNI RS06815
gene id: 768670:CALNI_RS06815
uniprot id: E4TJR4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

768670:CALNI RS03710
gene id: 768670:CALNI_RS03710
uniprot id: E4TGH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

768670:CALNI RS05555
gene id: 768670:CALNI_RS05555
uniprot id: E4TIA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

768670:CALNI RS09035
gene id: 768670:CALNI_RS09035
uniprot id: E4TGA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

768670:CALNI RS07725
gene id: 768670:CALNI_RS07725
uniprot id: E4TF01
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

768670:CALNI RS09940
gene id: 768670:CALNI_RS09940
uniprot id: E4THC3
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

768670:CALNI RS04875
gene id: 768670:CALNI_RS04875
uniprot id: E4THV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

768670:CALNI RS00970
gene id: 768670:CALNI_RS00970
uniprot id: E4TG93
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

768670:CALNI RS06585
gene id: 768670:CALNI_RS06585
uniprot id: E4TJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

768670:CALNI RS03185
gene id: 768670:CALNI_RS03185
uniprot id: E4TFZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

768670:CALNI RS07995
gene id: 768670:CALNI_RS07995
uniprot id: E4TF52
names: Similarity
messages: Belongs to the P(II) protein family.

768670:CALNI RS07265
gene id: 768670:CALNI_RS07265
uniprot id: E4TK73
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

768670:CALNI RS02050
gene id: 768670:CALNI_RS02050
uniprot id: E4TEJ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

768670:CALNI RS04840
gene id: 768670:CALNI_RS04840
uniprot id: E4THQ3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

768670:CALNI RS10405
gene id: 768670:CALNI_RS10405
uniprot id: E4THU1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

768670:CALNI RS09815
gene id: 768670:CALNI_RS09815
uniprot id: E4TH43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

768670:CALNI RS05240
gene id: 768670:CALNI_RS05240
uniprot id: E4TI41
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

768670:CALNI RS01370
gene id: 768670:CALNI_RS01370
uniprot id: E4TJM9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

768670:CALNI RS02820
gene id: 768670:CALNI_RS02820
uniprot id: E4TFK8
names: Similarity
messages: Belongs to the RutC family.

768670:CALNI RS06175
gene id: 768670:CALNI_RS06175
uniprot id: E4TJ08
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

768670:CALNI RS06590
gene id: 768670:CALNI_RS06590
uniprot id: E4TJF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

768670:CALNI RS00510
gene id: 768670:CALNI_RS00510
uniprot id: E4TIR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

768670:CALNI RS07550
gene id: 768670:CALNI_RS07550
uniprot id: E4TEQ0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

768670:CALNI RS00360
gene id: 768670:CALNI_RS00360
uniprot id: E4TIG4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

768670:CALNI RS07530
gene id: 768670:CALNI_RS07530
uniprot id: E4TEP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

768670:CALNI RS02510
gene id: 768670:CALNI_RS02510
uniprot id: E4TF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

768670:CALNI RS06925
gene id: 768670:CALNI_RS06925
uniprot id: E4TJT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

768670:CALNI RS07135
gene id: 768670:CALNI_RS07135
uniprot id: E4TK47
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

768670:CALNI RS02430
gene id: 768670:CALNI_RS02430
uniprot id: E4TEZ3
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS02095
gene id: 768670:CALNI_RS02095
uniprot id: E4TEK7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

768670:CALNI RS01010
gene id: 768670:CALNI_RS01010
uniprot id: E4TJ83
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

768670:CALNI RS09025
gene id: 768670:CALNI_RS09025
uniprot id: E4TGA6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

768670:CALNI RS04820
gene id: 768670:CALNI_RS04820
uniprot id: E4THP9
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS06610
gene id: 768670:CALNI_RS06610
uniprot id: E4TJG0
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS03315
gene id: 768670:CALNI_RS03315
uniprot id: E4TG24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

768670:CALNI RS05245
gene id: 768670:CALNI_RS05245
uniprot id: E4TI42
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

768670:CALNI RS10205
gene id: 768670:CALNI_RS10205
uniprot id: E4THH4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

768670:CALNI RS09445
gene id: 768670:CALNI_RS09445
uniprot id: E4TGR3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

768670:CALNI RS03115
gene id: 768670:CALNI_RS03115
uniprot id: E4TFR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

768670:CALNI RS09070
gene id: 768670:CALNI_RS09070
uniprot id: E4TGB5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

768670:CALNI RS09375
gene id: 768670:CALNI_RS09375
uniprot id: E4TGQ0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

768670:CALNI RS07170
gene id: 768670:CALNI_RS07170
uniprot id: E4TK54
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS07125
gene id: 768670:CALNI_RS07125
uniprot id: E4TK45
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

768670:CALNI RS07965
gene id: 768670:CALNI_RS07965
uniprot id: E4TF46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

768670:CALNI RS04040
gene id: 768670:CALNI_RS04040
uniprot id: E4TGV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

768670:CALNI RS07030
gene id: 768670:CALNI_RS07030
uniprot id: E4TK26
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS07395
gene id: 768670:CALNI_RS07395
uniprot id: E4TEL8
names: Similarity
messages: Belongs to the HypE family.

768670:CALNI RS00635
gene id: 768670:CALNI_RS00635
uniprot id: E4TIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

768670:CALNI RS01750
gene id: 768670:CALNI_RS01750
uniprot id: E4TK16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

768670:CALNI RS09790
gene id: 768670:CALNI_RS09790
uniprot id: E4TH38
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

768670:CALNI RS09960
gene id: 768670:CALNI_RS09960
uniprot id: E4THC7
names: Subcellular Location Annotation
messages: Membrane

768670:CALNI RS06220
gene id: 768670:CALNI_RS06220
uniprot id: E4TJ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

768670:CALNI RS06200
gene id: 768670:CALNI_RS06200
uniprot id: E4TJ13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

768670:CALNI RS02645
gene id: 768670:CALNI_RS02645
uniprot id: E4TFA2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

768670:CALNI RS10610
gene id: 768670:CALNI_RS10610
uniprot id: E4TKB5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

768670:CALNI RS07660
gene id: 768670:CALNI_RS07660
uniprot id: E4TES1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

768670:CALNI RS03200
gene id: 768670:CALNI_RS03200
uniprot id: E4TG01
names: Subcellular Location Annotation
messages: Mitochondrion

768670:CALNI RS03030
gene id: 768670:CALNI_RS03030
uniprot id: E4TFP8
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

768670:CALNI RS04400
gene id: 768670:CALNI_RS04400
uniprot id: E4TH97
names: Similarity
messages: Belongs to the UPF0047 family.

768670:CALNI RS02625
gene id: 768670:CALNI_RS02625
uniprot id: E4TF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

768670:CALNI RS03790
gene id: 768670:CALNI_RS03790
uniprot id: E4TGI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.