767434:FRAAU RS10650
gene id: 767434:FRAAU_RS10650
uniprot id: H8L456
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

767434:FRAAU RS03370
gene id: 767434:FRAAU_RS03370
uniprot id: H8KYM8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

767434:FRAAU RS06235
gene id: 767434:FRAAU_RS06235
uniprot id: H8L4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

767434:FRAAU RS15270
gene id: 767434:FRAAU_RS15270
uniprot id: H8L3P8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

767434:FRAAU RS05175
gene id: 767434:FRAAU_RS05175
uniprot id: H8L374
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine. In vitro, has also homoserine succinyl transferase activity.

767434:FRAAU RS00445
gene id: 767434:FRAAU_RS00445
uniprot id: H8KZT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

767434:FRAAU RS15550
gene id: 767434:FRAAU_RS15550
uniprot id: H8L0H8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

767434:FRAAU RS10890
gene id: 767434:FRAAU_RS10890
uniprot id: H8L4M7
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

767434:FRAAU RS11095
gene id: 767434:FRAAU_RS11095
uniprot id: H8L539
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

767434:FRAAU RS14130
gene id: 767434:FRAAU_RS14130
uniprot id: H8L137
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

767434:FRAAU RS01555
gene id: 767434:FRAAU_RS01555
uniprot id: H8L308
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS03255
gene id: 767434:FRAAU_RS03255
uniprot id: H8KYK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

767434:FRAAU RS05840
gene id: 767434:FRAAU_RS05840
uniprot id: H8L4G3
names: Similarity
messages: Belongs to the DEAD box helicase family.

767434:FRAAU RS10640
gene id: 767434:FRAAU_RS10640
uniprot id: H8L454
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

767434:FRAAU RS05905
gene id: 767434:FRAAU_RS05905
uniprot id: H8L4H6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS04610
gene id: 767434:FRAAU_RS04610
uniprot id: H8L1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

767434:FRAAU RS08410
gene id: 767434:FRAAU_RS08410
uniprot id: H8KYB9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS01965
gene id: 767434:FRAAU_RS01965
uniprot id: H8L3T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

767434:FRAAU RS12230
gene id: 767434:FRAAU_RS12230
uniprot id: H8L6L7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

767434:FRAAU RS08115
gene id: 767434:FRAAU_RS08115
uniprot id: H8KY63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

767434:FRAAU RS03310
gene id: 767434:FRAAU_RS03310
uniprot id: H8KYL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

767434:FRAAU RS14085
gene id: 767434:FRAAU_RS14085
uniprot id: H8L128
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

767434:FRAAU RS06430
gene id: 767434:FRAAU_RS06430
uniprot id: H8L526
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

767434:FRAAU RS10055
gene id: 767434:FRAAU_RS10055
uniprot id: H8L2Q9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

767434:FRAAU RS04500
gene id: 767434:FRAAU_RS04500
uniprot id: H8L1L9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

767434:FRAAU RS05425
gene id: 767434:FRAAU_RS05425
uniprot id: H8L3C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

767434:FRAAU RS14025
gene id: 767434:FRAAU_RS14025
uniprot id: H8L116
names: Similarity
messages: Belongs to the ABC transporter superfamily.

767434:FRAAU RS11225
gene id: 767434:FRAAU_RS11225
uniprot id: H8L564
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS09155
gene id: 767434:FRAAU_RS09155
uniprot id: H8L040
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

767434:FRAAU RS08930
gene id: 767434:FRAAU_RS08930
uniprot id: H8KZG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

767434:FRAAU RS11695
gene id: 767434:FRAAU_RS11695
uniprot id: H8L5Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

767434:FRAAU RS10085
gene id: 767434:FRAAU_RS10085
uniprot id: H8L2R5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS12695
gene id: 767434:FRAAU_RS12695
uniprot id: H8L702
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS04040
gene id: 767434:FRAAU_RS04040
uniprot id: H8L008
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

767434:FRAAU RS10030
gene id: 767434:FRAAU_RS10030
uniprot id: H8L2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

767434:FRAAU RS10365
gene id: 767434:FRAAU_RS10365
uniprot id: H8L3F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

767434:FRAAU RS03595
gene id: 767434:FRAAU_RS03595
uniprot id: H8KZ98
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS06755
gene id: 767434:FRAAU_RS06755
uniprot id: H8L5J6
names: Similarity
messages: Belongs to the proline racemase family.

767434:FRAAU RS09325
gene id: 767434:FRAAU_RS09325
uniprot id: H8L064
names: Similarity
messages: Belongs to the peptidase M24B family.

767434:FRAAU RS06175
gene id: 767434:FRAAU_RS06175
uniprot id: H8L4X6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

767434:FRAAU RS04595
gene id: 767434:FRAAU_RS04595
uniprot id: H8L1N9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

767434:FRAAU RS12110
gene id: 767434:FRAAU_RS12110
uniprot id: H8L6D4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

767434:FRAAU RS04420
gene id: 767434:FRAAU_RS04420
uniprot id: H8L0V7
names: Similarity
messages: Belongs to the RecJ family.

767434:FRAAU RS12455
gene id: 767434:FRAAU_RS12455
uniprot id: H8L6Q9
names: Similarity
messages: Belongs to the GSP E family.

767434:FRAAU RS05270
gene id: 767434:FRAAU_RS05270
uniprot id: H8L393
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

767434:FRAAU RS06985
gene id: 767434:FRAAU_RS06985
uniprot id: H8L5U2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

767434:FRAAU RS08690
gene id: 767434:FRAAU_RS08690
uniprot id: H8KYU3
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

767434:FRAAU RS03500
gene id: 767434:FRAAU_RS03500
uniprot id: H8KZ79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

767434:FRAAU RS15440
gene id: 767434:FRAAU_RS15440
uniprot id: H8L0F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS05255
gene id: 767434:FRAAU_RS05255
uniprot id: H8L390
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

767434:FRAAU RS12280
gene id: 767434:FRAAU_RS12280
uniprot id: H8L6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS05265
gene id: 767434:FRAAU_RS05265
uniprot id: H8L392
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

767434:FRAAU RS09290
gene id: 767434:FRAAU_RS09290
uniprot id: H8L057
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS10945
gene id: 767434:FRAAU_RS10945
uniprot id: H8L4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

767434:FRAAU RS06400
gene id: 767434:FRAAU_RS06400
uniprot id: H8L520
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

767434:FRAAU RS14480
gene id: 767434:FRAAU_RS14480
uniprot id: H8L205
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

767434:FRAAU RS00435
gene id: 767434:FRAAU_RS00435
uniprot id: H8KZS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

767434:FRAAU RS10950
gene id: 767434:FRAAU_RS10950
uniprot id: H8L4N7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

767434:FRAAU RS15510
gene id: 767434:FRAAU_RS15510
uniprot id: H8L0H1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

767434:FRAAU RS11770
gene id: 767434:FRAAU_RS11770
uniprot id: H8L601
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

767434:FRAAU RS01725
gene id: 767434:FRAAU_RS01725
uniprot id: H8L342
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

767434:FRAAU RS14230
gene id: 767434:FRAAU_RS14230
uniprot id: H8L155
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

767434:FRAAU RS11795
gene id: 767434:FRAAU_RS11795
uniprot id: H8L606
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS06355
gene id: 767434:FRAAU_RS06355
uniprot id: H8L511
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

767434:FRAAU RS09605
gene id: 767434:FRAAU_RS09605
uniprot id: H8L109
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

767434:FRAAU RS13755
gene id: 767434:FRAAU_RS13755
uniprot id: H8L080
names: Similarity
messages: Belongs to the heat shock protein 70 family.

767434:FRAAU RS03955
gene id: 767434:FRAAU_RS03955
uniprot id: H8KZZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

767434:FRAAU RS07065
gene id: 767434:FRAAU_RS07065
uniprot id: H8L5V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

767434:FRAAU RS09555
gene id: 767434:FRAAU_RS09555
uniprot id: H8L100
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

767434:FRAAU RS06575
gene id: 767434:FRAAU_RS06575
uniprot id: H8L5G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

767434:FRAAU RS09610
gene id: 767434:FRAAU_RS09610
uniprot id: H8L110
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

767434:FRAAU RS06925
gene id: 767434:FRAAU_RS06925
uniprot id: H8L5T0
names: Subunit
messages: Homodimer.

767434:FRAAU RS03195
gene id: 767434:FRAAU_RS03195
uniprot id: H8KYJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

767434:FRAAU RS03185
gene id: 767434:FRAAU_RS03185
uniprot id: H8KYJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

767434:FRAAU RS14775
gene id: 767434:FRAAU_RS14775
uniprot id: H8L2W3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS00975
gene id: 767434:FRAAU_RS00975
uniprot id: H8L1G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

767434:FRAAU RS11610
gene id: 767434:FRAAU_RS11610
uniprot id: H8L5R1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

767434:FRAAU RS03465
gene id: 767434:FRAAU_RS03465
uniprot id: H8KZ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

767434:FRAAU RS15210
gene id: 767434:FRAAU_RS15210
uniprot id: H8L3N6
names: Similarity
messages: Belongs to the DprA/Smf family.

767434:FRAAU RS00730
gene id: 767434:FRAAU_RS00730
uniprot id: H8L0L9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

767434:FRAAU RS12965
gene id: 767434:FRAAU_RS12965
uniprot id: H8KYF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

767434:FRAAU RS00450
gene id: 767434:FRAAU_RS00450
uniprot id: H8KZT1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

767434:FRAAU RS15080
gene id: 767434:FRAAU_RS15080
uniprot id: H8L3L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS00045
gene id: 767434:FRAAU_RS00045
uniprot id: H8KZ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

767434:FRAAU RS14765
gene id: 767434:FRAAU_RS14765
uniprot id: H8L2W1
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

767434:FRAAU RS05750
gene id: 767434:FRAAU_RS05750
uniprot id: H8L431
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS08355
gene id: 767434:FRAAU_RS08355
uniprot id: H8KYA8
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS06030
gene id: 767434:FRAAU_RS06030
uniprot id: H8L4J3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

767434:FRAAU RS08200
gene id: 767434:FRAAU_RS08200
uniprot id: H8KY80
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

767434:FRAAU RS14925
gene id: 767434:FRAAU_RS14925
uniprot id: H8L2Z0
names: Similarity
messages: Belongs to the DEAD box helicase family.

767434:FRAAU RS03750
gene id: 767434:FRAAU_RS03750
uniprot id: H8KZC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS04450
gene id: 767434:FRAAU_RS04450
uniprot id: H8L1K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

767434:FRAAU RS03180
gene id: 767434:FRAAU_RS03180
uniprot id: H8KYI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

767434:FRAAU RS05635
gene id: 767434:FRAAU_RS05635
uniprot id: H8L402
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

767434:FRAAU RS11545
gene id: 767434:FRAAU_RS11545
uniprot id: H8L5P8
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS05490
gene id: 767434:FRAAU_RS05490
uniprot id: H8L3X5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS12600
gene id: 767434:FRAAU_RS12600
uniprot id: H8L6Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

767434:FRAAU RS09400
gene id: 767434:FRAAU_RS09400
uniprot id: H8L0W9
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS03535
gene id: 767434:FRAAU_RS03535
uniprot id: H8KZ86
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS04530
gene id: 767434:FRAAU_RS04530
uniprot id: H8L1M5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS11930
gene id: 767434:FRAAU_RS11930
uniprot id: H8L6A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

767434:FRAAU RS15680
gene id: 767434:FRAAU_RS15680
uniprot id: H8L191
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

767434:FRAAU RS09860
gene id: 767434:FRAAU_RS09860
uniprot id: H8L1W8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

767434:FRAAU RS13150
gene id: 767434:FRAAU_RS13150
uniprot id: H8KYX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS01595
gene id: 767434:FRAAU_RS01595
uniprot id: H8L316
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

767434:FRAAU RS10125
gene id: 767434:FRAAU_RS10125
uniprot id: H8L2S3
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

767434:FRAAU RS04030
gene id: 767434:FRAAU_RS04030
uniprot id: H8L006
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

767434:FRAAU RS07645
gene id: 767434:FRAAU_RS07645
uniprot id: H8L6H4
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS01825
gene id: 767434:FRAAU_RS01825
uniprot id: H8L3Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

767434:FRAAU RS06320
gene id: 767434:FRAAU_RS06320
uniprot id: H8L504
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

767434:FRAAU RS15925
gene id: 767434:FRAAU_RS15925
uniprot id: H8L240
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS02445
gene id: 767434:FRAAU_RS02445
uniprot id: H8L4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

767434:FRAAU RS09950
gene id: 767434:FRAAU_RS09950
uniprot id: H8L2N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

767434:FRAAU RS12745
gene id: 767434:FRAAU_RS12745
uniprot id: H8L710
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

767434:FRAAU RS01835
gene id: 767434:FRAAU_RS01835
uniprot id: H8L3Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

767434:FRAAU RS10770
gene id: 767434:FRAAU_RS10770
uniprot id: H8L481
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS08945
gene id: 767434:FRAAU_RS08945
uniprot id: H8KZH1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

767434:FRAAU RS15720
gene id: 767434:FRAAU_RS15720
uniprot id: H8L198
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

767434:FRAAU RS16230
gene id: 767434:FRAAU_RS16230
uniprot id: H8L1E1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS15825
gene id: 767434:FRAAU_RS15825
uniprot id: H8L1C0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

767434:FRAAU RS10175
gene id: 767434:FRAAU_RS10175
uniprot id: H8L2T3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

767434:FRAAU RS03530
gene id: 767434:FRAAU_RS03530
uniprot id: H8KZ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

767434:FRAAU RS10965
gene id: 767434:FRAAU_RS10965
uniprot id: H8L4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

767434:FRAAU RS15715
gene id: 767434:FRAAU_RS15715
uniprot id: H8L197
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

767434:FRAAU RS13435
gene id: 767434:FRAAU_RS13435
uniprot id: H8KZJ7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

767434:FRAAU RS00300
gene id: 767434:FRAAU_RS00300
uniprot id: H8KZQ1
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS15880
gene id: 767434:FRAAU_RS15880
uniprot id: H8L1D0
names: Similarity
messages: Belongs to the OprB family.

767434:FRAAU RS02770
gene id: 767434:FRAAU_RS02770
uniprot id: H8L4W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

767434:FRAAU RS09940
gene id: 767434:FRAAU_RS09940
uniprot id: H8L2N6
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS08155
gene id: 767434:FRAAU_RS08155
uniprot id: H8KY71
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS10860
gene id: 767434:FRAAU_RS10860
uniprot id: H8L4M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

767434:FRAAU RS10875
gene id: 767434:FRAAU_RS10875
uniprot id: H8L4M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS10545
gene id: 767434:FRAAU_RS10545
uniprot id: H8L437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

767434:FRAAU RS05140
gene id: 767434:FRAAU_RS05140
uniprot id: H8L367
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS02895
gene id: 767434:FRAAU_RS02895
uniprot id: H8L5B1
names: Similarity
messages: Belongs to the peptidase M17 family.

767434:FRAAU RS12910
gene id: 767434:FRAAU_RS12910
uniprot id: H8KYE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

767434:FRAAU RS11305
gene id: 767434:FRAAU_RS11305
uniprot id: H8L575
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

767434:FRAAU RS10795
gene id: 767434:FRAAU_RS10795
uniprot id: H8L486
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS09120
gene id: 767434:FRAAU_RS09120
uniprot id: H8L033
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS10355
gene id: 767434:FRAAU_RS10355
uniprot id: H8L3F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

767434:FRAAU RS14680
gene id: 767434:FRAAU_RS14680
uniprot id: H8L2U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

767434:FRAAU RS11310
gene id: 767434:FRAAU_RS11310
uniprot id: H8L577
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

767434:FRAAU RS05815
gene id: 767434:FRAAU_RS05815
uniprot id: H8L4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS13255
gene id: 767434:FRAAU_RS13255
uniprot id: H8KYZ1
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

767434:FRAAU RS02885
gene id: 767434:FRAAU_RS02885
uniprot id: H8L5A9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

767434:FRAAU RS03215
gene id: 767434:FRAAU_RS03215
uniprot id: H8KYJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

767434:FRAAU RS00795
gene id: 767434:FRAAU_RS00795
uniprot id: H8L0N1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

767434:FRAAU RS00515
gene id: 767434:FRAAU_RS00515
uniprot id: H8KZU4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

767434:FRAAU RS14340
gene id: 767434:FRAAU_RS14340
uniprot id: H8L176
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

767434:FRAAU RS05785
gene id: 767434:FRAAU_RS05785
uniprot id: H8L4F2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

767434:FRAAU RS13355
gene id: 767434:FRAAU_RS13355
uniprot id: H8KZ11
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

767434:FRAAU RS09350
gene id: 767434:FRAAU_RS09350
uniprot id: H8L0W1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

767434:FRAAU RS08635
gene id: 767434:FRAAU_RS08635
uniprot id: H8KYT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

767434:FRAAU RS08130
gene id: 767434:FRAAU_RS08130
uniprot id: H8KY66
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

767434:FRAAU RS14255
gene id: 767434:FRAAU_RS14255
uniprot id: H8L160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS08065
gene id: 767434:FRAAU_RS08065
uniprot id: H8L6W1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS02690
gene id: 767434:FRAAU_RS02690
uniprot id: H8L4V3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS10285
gene id: 767434:FRAAU_RS10285
uniprot id: H8L3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

767434:FRAAU RS06305
gene id: 767434:FRAAU_RS06305
uniprot id: H8L501
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS12510
gene id: 767434:FRAAU_RS12510
uniprot id: H8L6X4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

767434:FRAAU RS03425
gene id: 767434:FRAAU_RS03425
uniprot id: H8KYN8
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS04235
gene id: 767434:FRAAU_RS04235
uniprot id: H8L0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

767434:FRAAU RS04180
gene id: 767434:FRAAU_RS04180
uniprot id: H8L0R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

767434:FRAAU RS01140
gene id: 767434:FRAAU_RS01140
uniprot id: H8L1J8
names: Similarity
messages: Belongs to the SsuE family.

767434:FRAAU RS02025
gene id: 767434:FRAAU_RS02025
uniprot id: H8L3U5
names: Similarity
messages: Belongs to the YicC/YloC family.

767434:FRAAU RS12360
gene id: 767434:FRAAU_RS12360
uniprot id: H8L6P0
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

767434:FRAAU RS06775
gene id: 767434:FRAAU_RS06775
uniprot id: H8L5K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS03360
gene id: 767434:FRAAU_RS03360
uniprot id: H8KYM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

767434:FRAAU RS14800
gene id: 767434:FRAAU_RS14800
uniprot id: H8L2W6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

767434:FRAAU RS06255
gene id: 767434:FRAAU_RS06255
uniprot id: H8L4Z2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

767434:FRAAU RS15590
gene id: 767434:FRAAU_RS15590
uniprot id: H8L0I6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS14185
gene id: 767434:FRAAU_RS14185
uniprot id: H8L146
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

767434:FRAAU RS10345
gene id: 767434:FRAAU_RS10345
uniprot id: H8L3F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

767434:FRAAU RS05595
gene id: 767434:FRAAU_RS05595
uniprot id: H8L3Z5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

767434:FRAAU RS07635
gene id: 767434:FRAAU_RS07635
uniprot id: H8L6H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS06375
gene id: 767434:FRAAU_RS06375
uniprot id: H8L515
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

767434:FRAAU RS12375
gene id: 767434:FRAAU_RS12375
uniprot id: H8L6P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

767434:FRAAU RS03380
gene id: 767434:FRAAU_RS03380
uniprot id: H8KYN0
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

767434:FRAAU RS01405
gene id: 767434:FRAAU_RS01405
uniprot id: H8L2E4
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

767434:FRAAU RS14280
gene id: 767434:FRAAU_RS14280
uniprot id: H8L165
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

767434:FRAAU RS06130
gene id: 767434:FRAAU_RS06130
uniprot id: H8L4K7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS02095
gene id: 767434:FRAAU_RS02095
uniprot id: H8L3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

767434:FRAAU RS09280
gene id: 767434:FRAAU_RS09280
uniprot id: H8L055
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

767434:FRAAU RS03335
gene id: 767434:FRAAU_RS03335
uniprot id: H8KYM1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

767434:FRAAU RS08015
gene id: 767434:FRAAU_RS08015
uniprot id: H8L6V1
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

767434:FRAAU RS11075
gene id: 767434:FRAAU_RS11075
uniprot id: H8L4Q9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

767434:FRAAU RS03170
gene id: 767434:FRAAU_RS03170
uniprot id: H8KYI7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

767434:FRAAU RS03845
gene id: 767434:FRAAU_RS03845
uniprot id: H8KZX0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

767434:FRAAU RS12165
gene id: 767434:FRAAU_RS12165
uniprot id: H8L6E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

767434:FRAAU RS08055
gene id: 767434:FRAAU_RS08055
uniprot id: H8L6V9
names: Similarity
messages: Belongs to the DapA family.

767434:FRAAU RS02030
gene id: 767434:FRAAU_RS02030
uniprot id: H8L3U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

767434:FRAAU RS06915
gene id: 767434:FRAAU_RS06915
uniprot id: H8L5S8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

767434:FRAAU RS13195
gene id: 767434:FRAAU_RS13195
uniprot id: H8KYX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

767434:FRAAU RS16235
gene id: 767434:FRAAU_RS16235
uniprot id: H8L1E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

767434:FRAAU RS07590
gene id: 767434:FRAAU_RS07590
uniprot id: H8L6G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

767434:FRAAU RS05845
gene id: 767434:FRAAU_RS05845
uniprot id: H8L4G4
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS05880
gene id: 767434:FRAAU_RS05880
uniprot id: H8L4H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

767434:FRAAU RS01860
gene id: 767434:FRAAU_RS01860
uniprot id: H8L3R2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

767434:FRAAU RS01430
gene id: 767434:FRAAU_RS01430
uniprot id: H8L2E9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

767434:FRAAU RS14215
gene id: 767434:FRAAU_RS14215
uniprot id: H8L152
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

767434:FRAAU RS01225
gene id: 767434:FRAAU_RS01225
uniprot id: H8L2A8
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS05190
gene id: 767434:FRAAU_RS05190
uniprot id: H8L377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

767434:FRAAU RS07115
gene id: 767434:FRAAU_RS07115
uniprot id: H8L5W5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS01545
gene id: 767434:FRAAU_RS01545
uniprot id: H8L306
names: Similarity
messages: Belongs to the UxaA family.

767434:FRAAU RS12055
gene id: 767434:FRAAU_RS12055
uniprot id: H8L6C4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

767434:FRAAU RS07060
gene id: 767434:FRAAU_RS07060
uniprot id: H8L5V6
names: Similarity
messages: Belongs to the XFP family.

767434:FRAAU RS06385
gene id: 767434:FRAAU_RS06385
uniprot id: H8L517
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

767434:FRAAU RS14820
gene id: 767434:FRAAU_RS14820
uniprot id: H8L2X0
names: Similarity
messages: Belongs to the CutA family.

767434:FRAAU RS14520
gene id: 767434:FRAAU_RS14520
uniprot id: H8L213
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

767434:FRAAU RS11840
gene id: 767434:FRAAU_RS11840
uniprot id: H8L616
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

767434:FRAAU RS06215
gene id: 767434:FRAAU_RS06215
uniprot id: H8L4Y3
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

767434:FRAAU RS06595
gene id: 767434:FRAAU_RS06595
uniprot id: H8L5G6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS09625
gene id: 767434:FRAAU_RS09625
uniprot id: H8L1S1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS13625
gene id: 767434:FRAAU_RS13625
uniprot id: H8KZN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

767434:FRAAU RS15495
gene id: 767434:FRAAU_RS15495
uniprot id: H8L0G8
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS04130
gene id: 767434:FRAAU_RS04130
uniprot id: H8L0Q2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

767434:FRAAU RS06390
gene id: 767434:FRAAU_RS06390
uniprot id: H8L518
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

767434:FRAAU RS08275
gene id: 767434:FRAAU_RS08275
uniprot id: H8KY95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS08395
gene id: 767434:FRAAU_RS08395
uniprot id: H8KYB5
names: Similarity
messages: Belongs to the asparagine synthetase family.

767434:FRAAU RS14070
gene id: 767434:FRAAU_RS14070
uniprot id: H8L125
names: Similarity
messages: Belongs to the UPF0225 family.

767434:FRAAU RS14440
gene id: 767434:FRAAU_RS14440
uniprot id: H8L1Z6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

767434:FRAAU RS10910
gene id: 767434:FRAAU_RS10910
uniprot id: H8L4N1
names: Similarity
messages: Belongs to the IMPACT family.

767434:FRAAU RS09005
gene id: 767434:FRAAU_RS09005
uniprot id: H8KZI3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

767434:FRAAU RS00310
gene id: 767434:FRAAU_RS00310
uniprot id: H8KZQ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

767434:FRAAU RS14490
gene id: 767434:FRAAU_RS14490
uniprot id: H8L207
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

767434:FRAAU RS14540
gene id: 767434:FRAAU_RS14540
uniprot id: H8L217
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

767434:FRAAU RS10275
gene id: 767434:FRAAU_RS10275
uniprot id: H8L3E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

767434:FRAAU RS01390
gene id: 767434:FRAAU_RS01390
uniprot id: H8L2E1
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS01000
gene id: 767434:FRAAU_RS01000
uniprot id: H8L1H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

767434:FRAAU RS02670
gene id: 767434:FRAAU_RS02670
uniprot id: H8L4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

767434:FRAAU RS13490
gene id: 767434:FRAAU_RS13490
uniprot id: H8KZK8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

767434:FRAAU RS10065
gene id: 767434:FRAAU_RS10065
uniprot id: H8L2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

767434:FRAAU RS15890
gene id: 767434:FRAAU_RS15890
uniprot id: H8L1D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

767434:FRAAU RS04625
gene id: 767434:FRAAU_RS04625
uniprot id: H8L1P5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

767434:FRAAU RS12290
gene id: 767434:FRAAU_RS12290
uniprot id: H8L6M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

767434:FRAAU RS11215
gene id: 767434:FRAAU_RS11215
uniprot id: H8L563
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS12265
gene id: 767434:FRAAU_RS12265
uniprot id: H8L6M4
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS11055
gene id: 767434:FRAAU_RS11055
uniprot id: H8L4Q5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

767434:FRAAU RS07765
gene id: 767434:FRAAU_RS07765
uniprot id: H8L6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

767434:FRAAU RS02945
gene id: 767434:FRAAU_RS02945
uniprot id: H8L5B9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

767434:FRAAU RS01840
gene id: 767434:FRAAU_RS01840
uniprot id: H8L3Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

767434:FRAAU RS10720
gene id: 767434:FRAAU_RS10720
uniprot id: H8L471
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

767434:FRAAU RS05455
gene id: 767434:FRAAU_RS05455
uniprot id: H8L3W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

767434:FRAAU RS08320
gene id: 767434:FRAAU_RS08320
uniprot id: H8KYA3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

767434:FRAAU RS16085
gene id: 767434:FRAAU_RS16085
uniprot id: H8L271
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

767434:FRAAU RS14325
gene id: 767434:FRAAU_RS14325
uniprot id: H8L173
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS12915
gene id: 767434:FRAAU_RS12915
uniprot id: H8KYE8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

767434:FRAAU RS08780
gene id: 767434:FRAAU_RS08780
uniprot id: H8KZD8
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

767434:FRAAU RS09420
gene id: 767434:FRAAU_RS09420
uniprot id: H8L0X3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

767434:FRAAU RS16190
gene id: 767434:FRAAU_RS16190
uniprot id: H8L291
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

767434:FRAAU RS06270
gene id: 767434:FRAAU_RS06270
uniprot id: H8L4Z5
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

767434:FRAAU RS07630
gene id: 767434:FRAAU_RS07630
uniprot id: H8L6H1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

767434:FRAAU RS16175
gene id: 767434:FRAAU_RS16175
uniprot id: H8L288
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

767434:FRAAU RS13530
gene id: 767434:FRAAU_RS13530
uniprot id: H8KZL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

767434:FRAAU RS02865
gene id: 767434:FRAAU_RS02865
uniprot id: H8L5A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

767434:FRAAU RS10170
gene id: 767434:FRAAU_RS10170
uniprot id: H8L2T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

767434:FRAAU RS14660
gene id: 767434:FRAAU_RS14660
uniprot id: H8L2U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

767434:FRAAU RS11010
gene id: 767434:FRAAU_RS11010
uniprot id: H8L4P7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

767434:FRAAU RS12105
gene id: 767434:FRAAU_RS12105
uniprot id: H8L6D3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

767434:FRAAU RS06360
gene id: 767434:FRAAU_RS06360
uniprot id: H8L512
names: Similarity
messages: Belongs to the CobH/CbiC family.

767434:FRAAU RS02905
gene id: 767434:FRAAU_RS02905
uniprot id: H8L5B3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

767434:FRAAU RS05740
gene id: 767434:FRAAU_RS05740
uniprot id: H8L423
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS06445
gene id: 767434:FRAAU_RS06445
uniprot id: H8L529
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS08955
gene id: 767434:FRAAU_RS08955
uniprot id: H8KZH3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

767434:FRAAU RS08610
gene id: 767434:FRAAU_RS08610
uniprot id: H8KYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

767434:FRAAU RS10575
gene id: 767434:FRAAU_RS10575
uniprot id: H8L443
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

767434:FRAAU RS03945
gene id: 767434:FRAAU_RS03945
uniprot id: H8KZY8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

767434:FRAAU RS13010
gene id: 767434:FRAAU_RS13010
uniprot id: H8KYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

767434:FRAAU RS04350
gene id: 767434:FRAAU_RS04350
uniprot id: H8L0U4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Homodimer.

767434:FRAAU RS06080
gene id: 767434:FRAAU_RS06080
uniprot id: H8L4K9
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

767434:FRAAU RS04545
gene id: 767434:FRAAU_RS04545
uniprot id: H8L1M8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

767434:FRAAU RS15985
gene id: 767434:FRAAU_RS15985
uniprot id: H8L252
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

767434:FRAAU RS03570
gene id: 767434:FRAAU_RS03570
uniprot id: H8KZ93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

767434:FRAAU RS12575
gene id: 767434:FRAAU_RS12575
uniprot id: H8L6X8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

767434:FRAAU RS03635
gene id: 767434:FRAAU_RS03635
uniprot id: H8KZA6
names: Subcellular Location Annotation
messages: Cytoplasm

767434:FRAAU RS11515
gene id: 767434:FRAAU_RS11515
uniprot id: H8L5P2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

767434:FRAAU RS11115
gene id: 767434:FRAAU_RS11115
uniprot id: H8L543
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

767434:FRAAU RS01625
gene id: 767434:FRAAU_RS01625
uniprot id: H8L322
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

767434:FRAAU RS15895
gene id: 767434:FRAAU_RS15895
uniprot id: H8L1D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

767434:FRAAU RS06635
gene id: 767434:FRAAU_RS06635
uniprot id: H8L5H3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

767434:FRAAU RS10340
gene id: 767434:FRAAU_RS10340
uniprot id: H8L3F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

767434:FRAAU RS10425
gene id: 767434:FRAAU_RS10425
uniprot id: H8L3G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

767434:FRAAU RS03200
gene id: 767434:FRAAU_RS03200
uniprot id: H8KYJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

767434:FRAAU RS05650
gene id: 767434:FRAAU_RS05650
uniprot id: H8L405
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

767434:FRAAU RS02975
gene id: 767434:FRAAU_RS02975
uniprot id: H8L5C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

767434:FRAAU RS03555
gene id: 767434:FRAAU_RS03555
uniprot id: H8KZ90
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS12970
gene id: 767434:FRAAU_RS12970
uniprot id: H8KYF9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

767434:FRAAU RS00985
gene id: 767434:FRAAU_RS00985
uniprot id: H8L1G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

767434:FRAAU RS16035
gene id: 767434:FRAAU_RS16035
uniprot id: H8L262
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

767434:FRAAU RS14040
gene id: 767434:FRAAU_RS14040
uniprot id: H8L119
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

767434:FRAAU RS02325
gene id: 767434:FRAAU_RS02325
uniprot id: H8L4C6
names: Similarity
messages: Belongs to the band 7/mec-2 family.

767434:FRAAU RS09935
gene id: 767434:FRAAU_RS09935
uniprot id: H8L2N5
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS02410
gene id: 767434:FRAAU_RS02410
uniprot id: H8L4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

767434:FRAAU RS12750
gene id: 767434:FRAAU_RS12750
uniprot id: H8L711
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS02600
gene id: 767434:FRAAU_RS02600
uniprot id: H8L4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

767434:FRAAU RS14170
gene id: 767434:FRAAU_RS14170
uniprot id: H8L143
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

767434:FRAAU RS11630
gene id: 767434:FRAAU_RS11630
uniprot id: H8L5X6
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

767434:FRAAU RS15285
gene id: 767434:FRAAU_RS15285
uniprot id: H8L3Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

767434:FRAAU RS01975
gene id: 767434:FRAAU_RS01975
uniprot id: H8L3T6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

767434:FRAAU RS14095
gene id: 767434:FRAAU_RS14095
uniprot id: H8L130
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS07605
gene id: 767434:FRAAU_RS07605
uniprot id: H8L6G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

767434:FRAAU RS00180
gene id: 767434:FRAAU_RS00180
uniprot id: H8KZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS04970
gene id: 767434:FRAAU_RS04970
uniprot id: H8L2K5
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

767434:FRAAU RS10705
gene id: 767434:FRAAU_RS10705
uniprot id: H8L468
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

767434:FRAAU RS00870
gene id: 767434:FRAAU_RS00870
uniprot id: H8L0P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

767434:FRAAU RS15785
gene id: 767434:FRAAU_RS15785
uniprot id: H8L1B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

767434:FRAAU RS07695
gene id: 767434:FRAAU_RS07695
uniprot id: H8L6I4
names: Similarity
messages: Belongs to the thioredoxin family.

767434:FRAAU RS10050
gene id: 767434:FRAAU_RS10050
uniprot id: H8L2Q8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

767434:FRAAU RS06475
gene id: 767434:FRAAU_RS06475
uniprot id: H8L537
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS01765
gene id: 767434:FRAAU_RS01765
uniprot id: H8L348
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

767434:FRAAU RS03660
gene id: 767434:FRAAU_RS03660
uniprot id: H8KZB1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS13455
gene id: 767434:FRAAU_RS13455
uniprot id: H8KZK1
names: Subcellular Location Annotation
messages: Mitochondrion

767434:FRAAU RS15745
gene id: 767434:FRAAU_RS15745
uniprot id: H8L1A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

767434:FRAAU RS06655
gene id: 767434:FRAAU_RS06655
uniprot id: H8L5H7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

767434:FRAAU RS07495
gene id: 767434:FRAAU_RS07495
uniprot id: H8L687
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

767434:FRAAU RS02685
gene id: 767434:FRAAU_RS02685
uniprot id: H8L4V2
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS08125
gene id: 767434:FRAAU_RS08125
uniprot id: H8KY65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS08030
gene id: 767434:FRAAU_RS08030
uniprot id: H8L6V4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

767434:FRAAU RS12180
gene id: 767434:FRAAU_RS12180
uniprot id: H8L6E8
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

767434:FRAAU RS05805
gene id: 767434:FRAAU_RS05805
uniprot id: H8L4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

767434:FRAAU RS09435
gene id: 767434:FRAAU_RS09435
uniprot id: H8L0X6
names: Similarity
messages: Belongs to the HesB/IscA family.

767434:FRAAU RS00020
gene id: 767434:FRAAU_RS00020
uniprot id: H8KZ24
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

767434:FRAAU RS14805
gene id: 767434:FRAAU_RS14805
uniprot id: H8L2W7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

767434:FRAAU RS00710
gene id: 767434:FRAAU_RS00710
uniprot id: H8L0L5
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

767434:FRAAU RS05800
gene id: 767434:FRAAU_RS05800
uniprot id: H8L4F5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

767434:FRAAU RS05615
gene id: 767434:FRAAU_RS05615
uniprot id: H8L3Z9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

767434:FRAAU RS07845
gene id: 767434:FRAAU_RS07845
uniprot id: H8L6R7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

767434:FRAAU RS04375
gene id: 767434:FRAAU_RS04375
uniprot id: H8L0U8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

767434:FRAAU RS11525
gene id: 767434:FRAAU_RS11525
uniprot id: H8L5P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS10480
gene id: 767434:FRAAU_RS10480
uniprot id: H8L3I4
names: Similarity
messages: Belongs to the SufE family.

767434:FRAAU RS07785
gene id: 767434:FRAAU_RS07785
uniprot id: H8L6K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

767434:FRAAU RS04005
gene id: 767434:FRAAU_RS04005
uniprot id: H8L001
names: Similarity
messages: Belongs to the SCO1/2 family.

767434:FRAAU RS14285
gene id: 767434:FRAAU_RS14285
uniprot id: H8L166
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

767434:FRAAU RS09865
gene id: 767434:FRAAU_RS09865
uniprot id: H8L1W9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

767434:FRAAU RS03985
gene id: 767434:FRAAU_RS03985
uniprot id: H8KZZ6
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS09920
gene id: 767434:FRAAU_RS09920
uniprot id: H8L2N2
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS05770
gene id: 767434:FRAAU_RS05770
uniprot id: H8L428
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS14245
gene id: 767434:FRAAU_RS14245
uniprot id: H8L158
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS14075
gene id: 767434:FRAAU_RS14075
uniprot id: H8L126
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

767434:FRAAU RS14045
gene id: 767434:FRAAU_RS14045
uniprot id: H8L120
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

767434:FRAAU RS04240
gene id: 767434:FRAAU_RS04240
uniprot id: H8L0S4
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

767434:FRAAU RS05415
gene id: 767434:FRAAU_RS05415
uniprot id: H8L3B8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

767434:FRAAU RS13180
gene id: 767434:FRAAU_RS13180
uniprot id: H8KYX6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

767434:FRAAU RS04340
gene id: 767434:FRAAU_RS04340
uniprot id: H8L0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

767434:FRAAU RS06580
gene id: 767434:FRAAU_RS06580
uniprot id: H8L5G3
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

767434:FRAAU RS03210
gene id: 767434:FRAAU_RS03210
uniprot id: H8KYJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

767434:FRAAU RS16595
gene id: 767434:FRAAU_RS16595
uniprot id: H8L625
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS12075
gene id: 767434:FRAAU_RS12075
uniprot id: H8L6C8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS09030
gene id: 767434:FRAAU_RS09030
uniprot id: H8KZI8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

767434:FRAAU RS00130
gene id: 767434:FRAAU_RS00130
uniprot id: H8KZ48
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

767434:FRAAU RS13015
gene id: 767434:FRAAU_RS13015
uniprot id: H8KYG8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS06700
gene id: 767434:FRAAU_RS06700
uniprot id: H8L5I6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

767434:FRAAU RS07550
gene id: 767434:FRAAU_RS07550
uniprot id: H8L6F5
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS02240
gene id: 767434:FRAAU_RS02240
uniprot id: H8L4A9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

767434:FRAAU RS02580
gene id: 767434:FRAAU_RS02580
uniprot id: H8L4T1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

767434:FRAAU RS15705
gene id: 767434:FRAAU_RS15705
uniprot id: H8L195
names: Similarity
messages: Belongs to the Dps family.

767434:FRAAU RS00765
gene id: 767434:FRAAU_RS00765
uniprot id: H8L0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS03375
gene id: 767434:FRAAU_RS03375
uniprot id: H8KYM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

767434:FRAAU RS08480
gene id: 767434:FRAAU_RS08480
uniprot id: H8KYQ4
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS12095
gene id: 767434:FRAAU_RS12095
uniprot id: H8L6D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

767434:FRAAU RS07025
gene id: 767434:FRAAU_RS07025
uniprot id: H8L5V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

767434:FRAAU RS06890
gene id: 767434:FRAAU_RS06890
uniprot id: H8L5S3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

767434:FRAAU RS09975
gene id: 767434:FRAAU_RS09975
uniprot id: H8L2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

767434:FRAAU RS07020
gene id: 767434:FRAAU_RS07020
uniprot id: H8L5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

767434:FRAAU RS01510
gene id: 767434:FRAAU_RS01510
uniprot id: H8L2Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

767434:FRAAU RS10410
gene id: 767434:FRAAU_RS10410
uniprot id: H8L3G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

767434:FRAAU RS03280
gene id: 767434:FRAAU_RS03280
uniprot id: H8KYL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

767434:FRAAU RS02825
gene id: 767434:FRAAU_RS02825
uniprot id: H8L597
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

767434:FRAAU RS10185
gene id: 767434:FRAAU_RS10185
uniprot id: H8L2T7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

767434:FRAAU RS03490
gene id: 767434:FRAAU_RS03490
uniprot id: H8KZ77
names: Subcellular Location Annotation
messages: Cytoplasm

767434:FRAAU RS13970
gene id: 767434:FRAAU_RS13970
uniprot id: H8L0C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS15325
gene id: 767434:FRAAU_RS15325
uniprot id: H8L0D3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

767434:FRAAU RS12935
gene id: 767434:FRAAU_RS12935
uniprot id: H8KYF2
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

767434:FRAAU RS03295
gene id: 767434:FRAAU_RS03295
uniprot id: H8KYL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

767434:FRAAU RS12420
gene id: 767434:FRAAU_RS12420
uniprot id: H8L6Q2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

767434:FRAAU RS00410
gene id: 767434:FRAAU_RS00410
uniprot id: H8KZS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

767434:FRAAU RS14690
gene id: 767434:FRAAU_RS14690
uniprot id: H8L2U6
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

767434:FRAAU RS12945
gene id: 767434:FRAAU_RS12945
uniprot id: H8KYF4
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

767434:FRAAU RS06815
gene id: 767434:FRAAU_RS06815
uniprot id: H8L5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

767434:FRAAU RS03125
gene id: 767434:FRAAU_RS03125
uniprot id: H8KYI2
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

767434:FRAAU RS16305
gene id: 767434:FRAAU_RS16305
uniprot id: H8L498
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS05640
gene id: 767434:FRAAU_RS05640
uniprot id: H8L403
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS13290
gene id: 767434:FRAAU_RS13290
uniprot id: H8KYZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

767434:FRAAU RS03485
gene id: 767434:FRAAU_RS03485
uniprot id: H8KZ76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

767434:FRAAU RS12450
gene id: 767434:FRAAU_RS12450
uniprot id: H8L6Q8
names: Similarity
messages: Belongs to the peptidase M13 family.

767434:FRAAU RS12675
gene id: 767434:FRAAU_RS12675
uniprot id: H8L6Z8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

767434:FRAAU RS11835
gene id: 767434:FRAAU_RS11835
uniprot id: H8L615
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS10205
gene id: 767434:FRAAU_RS10205
uniprot id: H8L3C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

767434:FRAAU RS05645
gene id: 767434:FRAAU_RS05645
uniprot id: H8L404
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

767434:FRAAU RS01760
gene id: 767434:FRAAU_RS01760
uniprot id: H8L347
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS06195
gene id: 767434:FRAAU_RS06195
uniprot id: H8L4Y0
names: Similarity
messages: Belongs to the TPP enzyme family.

767434:FRAAU RS13070
gene id: 767434:FRAAU_RS13070
uniprot id: H8KYH7
names: Similarity
messages: Belongs to the TPP enzyme family.

767434:FRAAU RS03720
gene id: 767434:FRAAU_RS03720
uniprot id: H8KZC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS12590
gene id: 767434:FRAAU_RS12590
uniprot id: H8L6Y1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

767434:FRAAU RS08935
gene id: 767434:FRAAU_RS08935
uniprot id: H8KZG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

767434:FRAAU RS14420
gene id: 767434:FRAAU_RS14420
uniprot id: H8L1Z2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

767434:FRAAU RS03365
gene id: 767434:FRAAU_RS03365
uniprot id: H8KYM7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

767434:FRAAU RS05375
gene id: 767434:FRAAU_RS05375
uniprot id: H8L3B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

767434:FRAAU RS03565
gene id: 767434:FRAAU_RS03565
uniprot id: H8KZ92
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

767434:FRAAU RS06190
gene id: 767434:FRAAU_RS06190
uniprot id: H8L4X9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

767434:FRAAU RS15900
gene id: 767434:FRAAU_RS15900
uniprot id: H8L1D4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

767434:FRAAU RS03450
gene id: 767434:FRAAU_RS03450
uniprot id: H8KZ68
names: Similarity
messages: Belongs to the peptidase U62 family.

767434:FRAAU RS00555
gene id: 767434:FRAAU_RS00555
uniprot id: H8KZV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS02020
gene id: 767434:FRAAU_RS02020
uniprot id: H8L3U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

767434:FRAAU RS15015
gene id: 767434:FRAAU_RS15015
uniprot id: H8L3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

767434:FRAAU RS03585
gene id: 767434:FRAAU_RS03585
uniprot id: H8KZ96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

767434:FRAAU RS14290
gene id: 767434:FRAAU_RS14290
uniprot id: H8L167
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

767434:FRAAU RS03290
gene id: 767434:FRAAU_RS03290
uniprot id: H8KYL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

767434:FRAAU RS02880
gene id: 767434:FRAAU_RS02880
uniprot id: H8L5A8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

767434:FRAAU RS00910
gene id: 767434:FRAAU_RS00910
uniprot id: H8L1F2
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS13215
gene id: 767434:FRAAU_RS13215
uniprot id: H8KYY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

767434:FRAAU RS12315
gene id: 767434:FRAAU_RS12315
uniprot id: H8L6N4
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

767434:FRAAU RS04535
gene id: 767434:FRAAU_RS04535
uniprot id: H8L1M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

767434:FRAAU RS06485
gene id: 767434:FRAAU_RS06485
uniprot id: H8L534
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

767434:FRAAU RS11495
gene id: 767434:FRAAU_RS11495
uniprot id: H8L5N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

767434:FRAAU RS07510
gene id: 767434:FRAAU_RS07510
uniprot id: H8L690
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

767434:FRAAU RS12800
gene id: 767434:FRAAU_RS12800
uniprot id: H8KYC7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

767434:FRAAU RS12025
gene id: 767434:FRAAU_RS12025
uniprot id: H8L6B9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS02125
gene id: 767434:FRAAU_RS02125
uniprot id: H8L3W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

767434:FRAAU RS14115
gene id: 767434:FRAAU_RS14115
uniprot id: H8L134
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

767434:FRAAU RS05095
gene id: 767434:FRAAU_RS05095
uniprot id: H8L2M7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

767434:FRAAU RS14235
gene id: 767434:FRAAU_RS14235
uniprot id: H8L156
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

767434:FRAAU RS13770
gene id: 767434:FRAAU_RS13770
uniprot id: H8L083
names: Similarity
messages: Belongs to the citrate synthase family.

767434:FRAAU RS02340
gene id: 767434:FRAAU_RS02340
uniprot id: H8L4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

767434:FRAAU RS15905
gene id: 767434:FRAAU_RS15905
uniprot id: H8L1D5
names: Similarity
messages: Belongs to the peptidase S9C family.

767434:FRAAU RS10755
gene id: 767434:FRAAU_RS10755
uniprot id: H8L478
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

767434:FRAAU RS02665
gene id: 767434:FRAAU_RS02665
uniprot id: H8L4U8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

767434:FRAAU RS03540
gene id: 767434:FRAAU_RS03540
uniprot id: H8KZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

767434:FRAAU RS06720
gene id: 767434:FRAAU_RS06720
uniprot id: H8L5J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

767434:FRAAU RS05405
gene id: 767434:FRAAU_RS05405
uniprot id: H8L3B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

767434:FRAAU RS04095
gene id: 767434:FRAAU_RS04095
uniprot id: H8L017
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

767434:FRAAU RS01730
gene id: 767434:FRAAU_RS01730
uniprot id: H8L343
names: Similarity
messages: Belongs to the peptidase S11 family.

767434:FRAAU RS03415
gene id: 767434:FRAAU_RS03415
uniprot id: H8KYN7
names: Similarity
messages: Belongs to the peptidase U62 family.

767434:FRAAU RS06620
gene id: 767434:FRAAU_RS06620
uniprot id: H8L5H0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

767434:FRAAU RS11430
gene id: 767434:FRAAU_RS11430
uniprot id: H8L5M5
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS03815
gene id: 767434:FRAAU_RS03815
uniprot id: H8KZW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

767434:FRAAU RS13285
gene id: 767434:FRAAU_RS13285
uniprot id: H8KYZ7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

767434:FRAAU RS00010
gene id: 767434:FRAAU_RS00010
uniprot id: H8KZ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

767434:FRAAU RS03320
gene id: 767434:FRAAU_RS03320
uniprot id: H8KYL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

767434:FRAAU RS13575
gene id: 767434:FRAAU_RS13575
uniprot id: H8KZM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

767434:FRAAU RS12460
gene id: 767434:FRAAU_RS12460
uniprot id: H8L6R0
names: Similarity
messages: Belongs to the GSP E family.

767434:FRAAU RS03710
gene id: 767434:FRAAU_RS03710
uniprot id: H8KZC0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

767434:FRAAU RS14850
gene id: 767434:FRAAU_RS14850
uniprot id: H8L2X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

767434:FRAAU RS02940
gene id: 767434:FRAAU_RS02940
uniprot id: H8L5B8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

767434:FRAAU RS03590
gene id: 767434:FRAAU_RS03590
uniprot id: H8KZ97
names: Similarity
messages: Belongs to the ArsC family.

767434:FRAAU RS10350
gene id: 767434:FRAAU_RS10350
uniprot id: H8L3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

767434:FRAAU RS00645
gene id: 767434:FRAAU_RS00645
uniprot id: H8L0K2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

767434:FRAAU RS13610
gene id: 767434:FRAAU_RS13610
uniprot id: H8KZN2
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

767434:FRAAU RS15230
gene id: 767434:FRAAU_RS15230
uniprot id: H8L3P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

767434:FRAAU RS09945
gene id: 767434:FRAAU_RS09945
uniprot id: H8L2N7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

767434:FRAAU RS02040
gene id: 767434:FRAAU_RS02040
uniprot id: H8L3U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

767434:FRAAU RS03575
gene id: 767434:FRAAU_RS03575
uniprot id: H8KZ94
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

767434:FRAAU RS09490
gene id: 767434:FRAAU_RS09490
uniprot id: H8L0Y7
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

767434:FRAAU RS09270
gene id: 767434:FRAAU_RS09270
uniprot id: H8L053
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

767434:FRAAU RS01875
gene id: 767434:FRAAU_RS01875
uniprot id: H8L3R5
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

767434:FRAAU RS11050
gene id: 767434:FRAAU_RS11050
uniprot id: H8L4Q4
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

767434:FRAAU RS03510
gene id: 767434:FRAAU_RS03510
uniprot id: H8KZ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

767434:FRAAU RS12385
gene id: 767434:FRAAU_RS12385
uniprot id: H8L6P5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

767434:FRAAU RS05395
gene id: 767434:FRAAU_RS05395
uniprot id: H8L3B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

767434:FRAAU RS11760
gene id: 767434:FRAAU_RS11760
uniprot id: H8L600
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

767434:FRAAU RS05720
gene id: 767434:FRAAU_RS05720
uniprot id: H8L419
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

767434:FRAAU RS05370
gene id: 767434:FRAAU_RS05370
uniprot id: H8L3B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

767434:FRAAU RS06405
gene id: 767434:FRAAU_RS06405
uniprot id: H8L521
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

767434:FRAAU RS12890
gene id: 767434:FRAAU_RS12890
uniprot id: H8KYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS08240
gene id: 767434:FRAAU_RS08240
uniprot id: H8KY88
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

767434:FRAAU RS08440
gene id: 767434:FRAAU_RS08440
uniprot id: H8KYP6
names: Similarity
messages: Belongs to the YciI family.

767434:FRAAU RS14670
gene id: 767434:FRAAU_RS14670
uniprot id: H8L2U2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS04540
gene id: 767434:FRAAU_RS04540
uniprot id: H8L1M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

767434:FRAAU RS06310
gene id: 767434:FRAAU_RS06310
uniprot id: H8L502
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

767434:FRAAU RS03250
gene id: 767434:FRAAU_RS03250
uniprot id: H8KYK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

767434:FRAAU RS14525
gene id: 767434:FRAAU_RS14525
uniprot id: H8L214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

767434:FRAAU RS16000
gene id: 767434:FRAAU_RS16000
uniprot id: H8L255
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

767434:FRAAU RS05450
gene id: 767434:FRAAU_RS05450
uniprot id: H8L3C5
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

767434:FRAAU RS07760
gene id: 767434:FRAAU_RS07760
uniprot id: H8L6J7
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS07725
gene id: 767434:FRAAU_RS07725
uniprot id: H8L6J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

767434:FRAAU RS08260
gene id: 767434:FRAAU_RS08260
uniprot id: H8KY92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

767434:FRAAU RS10560
gene id: 767434:FRAAU_RS10560
uniprot id: H8L440
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS08655
gene id: 767434:FRAAU_RS08655
uniprot id: H8KYT6
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

767434:FRAAU RS01290
gene id: 767434:FRAAU_RS01290
uniprot id: H8L2C1
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

767434:FRAAU RS02330
gene id: 767434:FRAAU_RS02330
uniprot id: H8L4C7
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS04055
gene id: 767434:FRAAU_RS04055
uniprot id: H8L011
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

767434:FRAAU RS03240
gene id: 767434:FRAAU_RS03240
uniprot id: H8KYK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

767434:FRAAU RS03175
gene id: 767434:FRAAU_RS03175
uniprot id: H8KYI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

767434:FRAAU RS01300
gene id: 767434:FRAAU_RS01300
uniprot id: H8L2C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

767434:FRAAU RS12620
gene id: 767434:FRAAU_RS12620
uniprot id: H8L6Y6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

767434:FRAAU RS08190
gene id: 767434:FRAAU_RS08190
uniprot id: H8KY78
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

767434:FRAAU RS06265
gene id: 767434:FRAAU_RS06265
uniprot id: H8L4Z4
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

767434:FRAAU RS02530
gene id: 767434:FRAAU_RS02530
uniprot id: H8L4S6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS11570
gene id: 767434:FRAAU_RS11570
uniprot id: H8L5Q3
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

767434:FRAAU RS14200
gene id: 767434:FRAAU_RS14200
uniprot id: H8L149
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

767434:FRAAU RS09990
gene id: 767434:FRAAU_RS09990
uniprot id: H8L2P6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

767434:FRAAU RS15365
gene id: 767434:FRAAU_RS15365
uniprot id: H8L0E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

767434:FRAAU RS10625
gene id: 767434:FRAAU_RS10625
uniprot id: H8L452
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS04505
gene id: 767434:FRAAU_RS04505
uniprot id: H8L1M0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS10605
gene id: 767434:FRAAU_RS10605
uniprot id: H8L448
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS14030
gene id: 767434:FRAAU_RS14030
uniprot id: H8L117
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS11585
gene id: 767434:FRAAU_RS11585
uniprot id: H8L5Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

767434:FRAAU RS06900
gene id: 767434:FRAAU_RS06900
uniprot id: H8L5S5
names: Similarity
messages: Belongs to the fabD family.

767434:FRAAU RS05275
gene id: 767434:FRAAU_RS05275
uniprot id: H8L394
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

767434:FRAAU RS14435
gene id: 767434:FRAAU_RS14435
uniprot id: H8L1Z5
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

767434:FRAAU RS00110
gene id: 767434:FRAAU_RS00110
uniprot id: H8KZ44
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS05855
gene id: 767434:FRAAU_RS05855
uniprot id: H8L4G6
names: Similarity
messages: Belongs to the peptidase C40 family.

767434:FRAAU RS11120
gene id: 767434:FRAAU_RS11120
uniprot id: H8L544
names: Similarity
messages: Belongs to the PhoH family.

767434:FRAAU RS14335
gene id: 767434:FRAAU_RS14335
uniprot id: H8L175
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

767434:FRAAU RS11100
gene id: 767434:FRAAU_RS11100
uniprot id: H8L540
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

767434:FRAAU RS09320
gene id: 767434:FRAAU_RS09320
uniprot id: H8L063
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS14035
gene id: 767434:FRAAU_RS14035
uniprot id: H8L118
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

767434:FRAAU RS03130
gene id: 767434:FRAAU_RS03130
uniprot id: H8KYI3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

767434:FRAAU RS00005
gene id: 767434:FRAAU_RS00005
uniprot id: H8KZ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

767434:FRAAU RS16130
gene id: 767434:FRAAU_RS16130
uniprot id: H8L280
names: Similarity
messages: Belongs to the UPF0758 family.

767434:FRAAU RS07000
gene id: 767434:FRAAU_RS07000
uniprot id: H8L5U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

767434:FRAAU RS03205
gene id: 767434:FRAAU_RS03205
uniprot id: H8KYJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

767434:FRAAU RS00015
gene id: 767434:FRAAU_RS00015
uniprot id: H8KZ23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

767434:FRAAU RS10035
gene id: 767434:FRAAU_RS10035
uniprot id: H8L2Q5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

767434:FRAAU RS15770
gene id: 767434:FRAAU_RS15770
uniprot id: H8L1A9
names: Similarity
messages: Belongs to the threonine synthase family.

767434:FRAAU RS02970
gene id: 767434:FRAAU_RS02970
uniprot id: H8L5C3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

767434:FRAAU RS05575
gene id: 767434:FRAAU_RS05575
uniprot id: H8L3Z1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

767434:FRAAU RS14415
gene id: 767434:FRAAU_RS14415
uniprot id: H8L1Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS05890
gene id: 767434:FRAAU_RS05890
uniprot id: H8L4H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

767434:FRAAU RS05400
gene id: 767434:FRAAU_RS05400
uniprot id: H8L3B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

767434:FRAAU RS09015
gene id: 767434:FRAAU_RS09015
uniprot id: H8KZI5
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS14055
gene id: 767434:FRAAU_RS14055
uniprot id: H8L122
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

767434:FRAAU RS15370
gene id: 767434:FRAAU_RS15370
uniprot id: H8L0E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

767434:FRAAU RS10330
gene id: 767434:FRAAU_RS10330
uniprot id: H8L3F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

767434:FRAAU RS07585
gene id: 767434:FRAAU_RS07585
uniprot id: H8L6G2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

767434:FRAAU RS15145
gene id: 767434:FRAAU_RS15145
uniprot id: H8L3M4
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

767434:FRAAU RS14510
gene id: 767434:FRAAU_RS14510
uniprot id: H8L211
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

767434:FRAAU RS06590
gene id: 767434:FRAAU_RS06590
uniprot id: H8L5G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

767434:FRAAU RS01680
gene id: 767434:FRAAU_RS01680
uniprot id: H8L333
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

767434:FRAAU RS10220
gene id: 767434:FRAAU_RS10220
uniprot id: H8L3C9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

767434:FRAAU RS14740
gene id: 767434:FRAAU_RS14740
uniprot id: H8L2V6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.

767434:FRAAU RS01785
gene id: 767434:FRAAU_RS01785
uniprot id: H8L352
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

767434:FRAAU RS15155
gene id: 767434:FRAAU_RS15155
uniprot id: H8L3M6
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

767434:FRAAU RS13860
gene id: 767434:FRAAU_RS13860
uniprot id: H8L0A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

767434:FRAAU RS06300
gene id: 767434:FRAAU_RS06300
uniprot id: H8L500
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS05885
gene id: 767434:FRAAU_RS05885
uniprot id: H8L4H2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

767434:FRAAU RS13295
gene id: 767434:FRAAU_RS13295
uniprot id: H8KYZ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

767434:FRAAU RS02175
gene id: 767434:FRAAU_RS02175
uniprot id: H8L496
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

767434:FRAAU RS10405
gene id: 767434:FRAAU_RS10405
uniprot id: H8L3G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

767434:FRAAU RS05830
gene id: 767434:FRAAU_RS05830
uniprot id: H8L4G1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS14780
gene id: 767434:FRAAU_RS14780
uniprot id: H8L2W4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

767434:FRAAU RS05670
gene id: 767434:FRAAU_RS05670
uniprot id: H8L409
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

767434:FRAAU RS07755
gene id: 767434:FRAAU_RS07755
uniprot id: H8L6J6
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS12305
gene id: 767434:FRAAU_RS12305
uniprot id: H8L6N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

767434:FRAAU RS14595
gene id: 767434:FRAAU_RS14595
uniprot id: H8L226
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

767434:FRAAU RS12580
gene id: 767434:FRAAU_RS12580
uniprot id: H8L6X9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

767434:FRAAU RS05920
gene id: 767434:FRAAU_RS05920
uniprot id: H8L4H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

767434:FRAAU RS01930
gene id: 767434:FRAAU_RS01930
uniprot id: H8L3S6
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

767434:FRAAU RS10295
gene id: 767434:FRAAU_RS10295
uniprot id: H8L3E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

767434:FRAAU RS14975
gene id: 767434:FRAAU_RS14975
uniprot id: H8L3I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

767434:FRAAU RS06930
gene id: 767434:FRAAU_RS06930
uniprot id: H8L5T1
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

767434:FRAAU RS01830
gene id: 767434:FRAAU_RS01830
uniprot id: H8L3Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS03665
gene id: 767434:FRAAU_RS03665
uniprot id: H8KZB2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS08255
gene id: 767434:FRAAU_RS08255
uniprot id: H8KY91
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

767434:FRAAU RS00305
gene id: 767434:FRAAU_RS00305
uniprot id: H8KZQ2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

767434:FRAAU RS11490
gene id: 767434:FRAAU_RS11490
uniprot id: H8L5N7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

767434:FRAAU RS01400
gene id: 767434:FRAAU_RS01400
uniprot id: H8L2E3
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

767434:FRAAU RS02785
gene id: 767434:FRAAU_RS02785
uniprot id: H8L588
names: Similarity
messages: Belongs to the CFA/CMAS family.

767434:FRAAU RS10310
gene id: 767434:FRAAU_RS10310
uniprot id: H8L3E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

767434:FRAAU RS06605
gene id: 767434:FRAAU_RS06605
uniprot id: H8L5G7
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS00995
gene id: 767434:FRAAU_RS00995
uniprot id: H8L1G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

767434:FRAAU RS14305
gene id: 767434:FRAAU_RS14305
uniprot id: H8L170
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS07615
gene id: 767434:FRAAU_RS07615
uniprot id: H8L6G8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

767434:FRAAU RS13785
gene id: 767434:FRAAU_RS13785
uniprot id: H8L086
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

767434:FRAAU RS12470
gene id: 767434:FRAAU_RS12470
uniprot id: H8L6R2
names: Similarity
messages: Belongs to the YggT family.

767434:FRAAU RS10335
gene id: 767434:FRAAU_RS10335
uniprot id: H8L3F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

767434:FRAAU RS08135
gene id: 767434:FRAAU_RS08135
uniprot id: H8KY67
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

767434:FRAAU RS11735
gene id: 767434:FRAAU_RS11735
uniprot id: H8L5Z5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

767434:FRAAU RS16005
gene id: 767434:FRAAU_RS16005
uniprot id: H8L256
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

767434:FRAAU RS02795
gene id: 767434:FRAAU_RS02795
uniprot id: H8L590
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

767434:FRAAU RS14050
gene id: 767434:FRAAU_RS14050
uniprot id: H8L121
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

767434:FRAAU RS13135
gene id: 767434:FRAAU_RS13135
uniprot id: H8KYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

767434:FRAAU RS05665
gene id: 767434:FRAAU_RS05665
uniprot id: H8L408
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

767434:FRAAU RS02070
gene id: 767434:FRAAU_RS02070
uniprot id: H8L3V4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

767434:FRAAU RS15565
gene id: 767434:FRAAU_RS15565
uniprot id: H8L0I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS01685
gene id: 767434:FRAAU_RS01685
uniprot id: H8L334
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS17380
gene id: 767434:FRAAU_RS17380
uniprot id: H8L002
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

767434:FRAAU RS01505
gene id: 767434:FRAAU_RS01505
uniprot id: H8L2G2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

767434:FRAAU RS08810
gene id: 767434:FRAAU_RS08810
uniprot id: H8KZE4
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS06410
gene id: 767434:FRAAU_RS06410
uniprot id: H8L522
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

767434:FRAAU RS07655
gene id: 767434:FRAAU_RS07655
uniprot id: H8L6H6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS14400
gene id: 767434:FRAAU_RS14400
uniprot id: H8L1Y8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

767434:FRAAU RS10385
gene id: 767434:FRAAU_RS10385
uniprot id: H8L3G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

767434:FRAAU RS15265
gene id: 767434:FRAAU_RS15265
uniprot id: H8L3P7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

767434:FRAAU RS11660
gene id: 767434:FRAAU_RS11660
uniprot id: H8L5Y1
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

767434:FRAAU RS15200
gene id: 767434:FRAAU_RS15200
uniprot id: H8L3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

767434:FRAAU RS05600
gene id: 767434:FRAAU_RS05600
uniprot id: H8L3Z6
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS09630
gene id: 767434:FRAAU_RS09630
uniprot id: H8L1S2
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS01870
gene id: 767434:FRAAU_RS01870
uniprot id: H8L3R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

767434:FRAAU RS13865
gene id: 767434:FRAAU_RS13865
uniprot id: H8L0A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

767434:FRAAU RS15220
gene id: 767434:FRAAU_RS15220
uniprot id: H8L3N8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

767434:FRAAU RS15020
gene id: 767434:FRAAU_RS15020
uniprot id: H8L3J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

767434:FRAAU RS05460
gene id: 767434:FRAAU_RS05460
uniprot id: H8L3W9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

767434:FRAAU RS15620
gene id: 767434:FRAAU_RS15620
uniprot id: H8L179
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

767434:FRAAU RS06295
gene id: 767434:FRAAU_RS06295
uniprot id: H8L4Z9
names: Similarity
messages: Belongs to the BolA/IbaG family.

767434:FRAAU RS14205
gene id: 767434:FRAAU_RS14205
uniprot id: H8L150
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

767434:FRAAU RS16560
gene id: 767434:FRAAU_RS16560
uniprot id: H8L4L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS04630
gene id: 767434:FRAAU_RS04630
uniprot id: H8L1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

767434:FRAAU RS00965
gene id: 767434:FRAAU_RS00965
uniprot id: H8L1G3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

767434:FRAAU RS14060
gene id: 767434:FRAAU_RS14060
uniprot id: H8L123
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

767434:FRAAU RS15575
gene id: 767434:FRAAU_RS15575
uniprot id: H8L0I3
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

767434:FRAAU RS00350
gene id: 767434:FRAAU_RS00350
uniprot id: H8KZR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

767434:FRAAU RS03515
gene id: 767434:FRAAU_RS03515
uniprot id: H8KZ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

767434:FRAAU RS05205
gene id: 767434:FRAAU_RS05205
uniprot id: H8L380
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

767434:FRAAU RS05620
gene id: 767434:FRAAU_RS05620
uniprot id: H8L400
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

767434:FRAAU RS00040
gene id: 767434:FRAAU_RS00040
uniprot id: H8KZ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

767434:FRAAU RS10935
gene id: 767434:FRAAU_RS10935
uniprot id: H8L4N4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

767434:FRAAU RS02680
gene id: 767434:FRAAU_RS02680
uniprot id: H8L4V1
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS13525
gene id: 767434:FRAAU_RS13525
uniprot id: H8KZL5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

767434:FRAAU RS02790
gene id: 767434:FRAAU_RS02790
uniprot id: H8L589
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS15190
gene id: 767434:FRAAU_RS15190
uniprot id: H8L3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

767434:FRAAU RS11385
gene id: 767434:FRAAU_RS11385
uniprot id: H8L5L6
names: Similarity
messages: Belongs to the peptidase M13 family.

767434:FRAAU RS08660
gene id: 767434:FRAAU_RS08660
uniprot id: H8KYT7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

767434:FRAAU RS03285
gene id: 767434:FRAAU_RS03285
uniprot id: H8KYL1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

767434:FRAAU RS06995
gene id: 767434:FRAAU_RS06995
uniprot id: H8L5U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

767434:FRAAU RS14210
gene id: 767434:FRAAU_RS14210
uniprot id: H8L151
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

767434:FRAAU RS01920
gene id: 767434:FRAAU_RS01920
uniprot id: H8L3S4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

767434:FRAAU RS05390
gene id: 767434:FRAAU_RS05390
uniprot id: H8L3B3
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

767434:FRAAU RS11535
gene id: 767434:FRAAU_RS11535
uniprot id: H8L5P6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

767434:FRAAU RS11030
gene id: 767434:FRAAU_RS11030
uniprot id: H8L4Q0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS15650
gene id: 767434:FRAAU_RS15650
uniprot id: H8L185
names: Similarity
messages: Belongs to the OsmC/Ohr family.

767434:FRAAU RS13050
gene id: 767434:FRAAU_RS13050
uniprot id: H8KYH9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

767434:FRAAU RS04870
gene id: 767434:FRAAU_RS04870
uniprot id: H8L2I5
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

767434:FRAAU RS00915
gene id: 767434:FRAAU_RS00915
uniprot id: H8L1F3
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS00475
gene id: 767434:FRAAU_RS00475
uniprot id: H8KZT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS05810
gene id: 767434:FRAAU_RS05810
uniprot id: H8L4F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

767434:FRAAU RS09180
gene id: 767434:FRAAU_RS09180
uniprot id: H8L045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

767434:FRAAU RS08025
gene id: 767434:FRAAU_RS08025
uniprot id: H8L6V3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

767434:FRAAU RS08590
gene id: 767434:FRAAU_RS08590
uniprot id: H8KYS3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

767434:FRAAU RS02640
gene id: 767434:FRAAU_RS02640
uniprot id: H8L4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

767434:FRAAU RS05660
gene id: 767434:FRAAU_RS05660
uniprot id: H8L407
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

767434:FRAAU RS09885
gene id: 767434:FRAAU_RS09885
uniprot id: H8L1X6
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

767434:FRAAU RS13685
gene id: 767434:FRAAU_RS13685
uniprot id: H8L071
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

767434:FRAAU RS15945
gene id: 767434:FRAAU_RS15945
uniprot id: H8L244
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

767434:FRAAU RS02535
gene id: 767434:FRAAU_RS02535
uniprot id: H8L4S7
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

767434:FRAAU RS03300
gene id: 767434:FRAAU_RS03300
uniprot id: H8KYL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

767434:FRAAU RS14295
gene id: 767434:FRAAU_RS14295
uniprot id: H8L168
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

767434:FRAAU RS03795
gene id: 767434:FRAAU_RS03795
uniprot id: H8KZW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

767434:FRAAU RS03355
gene id: 767434:FRAAU_RS03355
uniprot id: H8KYM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

767434:FRAAU RS15435
gene id: 767434:FRAAU_RS15435
uniprot id: H8L0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

767434:FRAAU RS06965
gene id: 767434:FRAAU_RS06965
uniprot id: H8L5T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

767434:FRAAU RS10870
gene id: 767434:FRAAU_RS10870
uniprot id: H8L4M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

767434:FRAAU RS13995
gene id: 767434:FRAAU_RS13995
uniprot id: H8L0C5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

767434:FRAAU RS01855
gene id: 767434:FRAAU_RS01855
uniprot id: H8L3R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

767434:FRAAU RS14015
gene id: 767434:FRAAU_RS14015
uniprot id: H8L114
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

767434:FRAAU RS15235
gene id: 767434:FRAAU_RS15235
uniprot id: H8L3P1
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS02245
gene id: 767434:FRAAU_RS02245
uniprot id: H8L4B0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

767434:FRAAU RS07010
gene id: 767434:FRAAU_RS07010
uniprot id: H8L5U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

767434:FRAAU RS07940
gene id: 767434:FRAAU_RS07940
uniprot id: H8L6T7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

767434:FRAAU RS04305
gene id: 767434:FRAAU_RS04305
uniprot id: H8L0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

767434:FRAAU RS01790
gene id: 767434:FRAAU_RS01790
uniprot id: H8L353
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

767434:FRAAU RS07840
gene id: 767434:FRAAU_RS07840
uniprot id: H8L6R6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

767434:FRAAU RS03245
gene id: 767434:FRAAU_RS03245
uniprot id: H8KYK3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

767434:FRAAU RS10280
gene id: 767434:FRAAU_RS10280
uniprot id: H8L3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

767434:FRAAU RS02890
gene id: 767434:FRAAU_RS02890
uniprot id: H8L5B0
names: Similarity
messages: Belongs to the peptidase S41A family.

767434:FRAAU RS14810
gene id: 767434:FRAAU_RS14810
uniprot id: H8L2W8
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS15610
gene id: 767434:FRAAU_RS15610
uniprot id: H8L0J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

767434:FRAAU RS15065
gene id: 767434:FRAAU_RS15065
uniprot id: H8L3K8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS00505
gene id: 767434:FRAAU_RS00505
uniprot id: H8KZU2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS05560
gene id: 767434:FRAAU_RS05560
uniprot id: H8L3Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

767434:FRAAU RS12260
gene id: 767434:FRAAU_RS12260
uniprot id: H8L6M3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

767434:FRAAU RS15400
gene id: 767434:FRAAU_RS15400
uniprot id: H8L0E7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

767434:FRAAU RS02660
gene id: 767434:FRAAU_RS02660
uniprot id: H8L4U7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

767434:FRAAU RS17475
gene id: 767434:FRAAU_RS17475
uniprot id: H8L181
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

767434:FRAAU RS13570
gene id: 767434:FRAAU_RS13570
uniprot id: H8KZM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

767434:FRAAU RS13870
gene id: 767434:FRAAU_RS13870
uniprot id: H8L0A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

767434:FRAAU RS14915
gene id: 767434:FRAAU_RS14915
uniprot id: H8L2Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS02255
gene id: 767434:FRAAU_RS02255
uniprot id: H8L4B2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

767434:FRAAU RS14815
gene id: 767434:FRAAU_RS14815
uniprot id: H8L2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS06895
gene id: 767434:FRAAU_RS06895
uniprot id: H8L5S4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

767434:FRAAU RS02010
gene id: 767434:FRAAU_RS02010
uniprot id: H8L3U3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

767434:FRAAU RS05925
gene id: 767434:FRAAU_RS05925
uniprot id: H8L4I0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS13060
gene id: 767434:FRAAU_RS13060
uniprot id: H8KYH5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS03005
gene id: 767434:FRAAU_RS03005
uniprot id: H8L5D1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

767434:FRAAU RS13360
gene id: 767434:FRAAU_RS13360
uniprot id: H8KZ12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

767434:FRAAU RS04525
gene id: 767434:FRAAU_RS04525
uniprot id: H8L1M4
names: Similarity
messages: Belongs to the TrpF family.

767434:FRAAU RS12960
gene id: 767434:FRAAU_RS12960
uniprot id: H8KYF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS12920
gene id: 767434:FRAAU_RS12920
uniprot id: H8KYE9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

767434:FRAAU RS15570
gene id: 767434:FRAAU_RS15570
uniprot id: H8L0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

767434:FRAAU RS01900
gene id: 767434:FRAAU_RS01900
uniprot id: H8L3S0
names: Similarity
messages: Belongs to the histone deacetylase family.

767434:FRAAU RS14320
gene id: 767434:FRAAU_RS14320
uniprot id: H8L172
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS12705
gene id: 767434:FRAAU_RS12705
uniprot id: H8L704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS16245
gene id: 767434:FRAAU_RS16245
uniprot id: H8L1E4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

767434:FRAAU RS13825
gene id: 767434:FRAAU_RS13825
uniprot id: H8L095
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

767434:FRAAU RS03265
gene id: 767434:FRAAU_RS03265
uniprot id: H8KYK7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

767434:FRAAU RS03270
gene id: 767434:FRAAU_RS03270
uniprot id: H8KYK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

767434:FRAAU RS03015
gene id: 767434:FRAAU_RS03015
uniprot id: H8L5D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

767434:FRAAU RS09955
gene id: 767434:FRAAU_RS09955
uniprot id: H8L2N9
names: Similarity
messages: Belongs to the YfgM family.

767434:FRAAU RS01970
gene id: 767434:FRAAU_RS01970
uniprot id: H8L3T5
names: Subcellular Location Annotation
messages: Nucleus

767434:FRAAU RS04160
gene id: 767434:FRAAU_RS04160
uniprot id: H8L0Q8
names: Similarity
messages: Belongs to the universal stress protein A family.

767434:FRAAU RS06715
gene id: 767434:FRAAU_RS06715
uniprot id: H8L5I9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

767434:FRAAU RS13545
gene id: 767434:FRAAU_RS13545
uniprot id: H8KZL9
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS10940
gene id: 767434:FRAAU_RS10940
uniprot id: H8L4N5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

767434:FRAAU RS01940
gene id: 767434:FRAAU_RS01940
uniprot id: H8L3S8
names: Similarity
messages: Belongs to the pyruvate kinase family.

767434:FRAAU RS11690
gene id: 767434:FRAAU_RS11690
uniprot id: H8L5Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS05790
gene id: 767434:FRAAU_RS05790
uniprot id: H8L4F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

767434:FRAAU RS04155
gene id: 767434:FRAAU_RS04155
uniprot id: H8L0Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

767434:FRAAU RS15180
gene id: 767434:FRAAU_RS15180
uniprot id: H8L3N1
names: Similarity
messages: Belongs to the GARS family.

767434:FRAAU RS07580
gene id: 767434:FRAAU_RS07580
uniprot id: H8L6G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

767434:FRAAU RS14950
gene id: 767434:FRAAU_RS14950
uniprot id: H8L2Z5
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

767434:FRAAU RS10375
gene id: 767434:FRAAU_RS10375
uniprot id: H8L3F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

767434:FRAAU RS15935
gene id: 767434:FRAAU_RS15935
uniprot id: H8L242
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS15445
gene id: 767434:FRAAU_RS15445
uniprot id: H8L0F6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS13040
gene id: 767434:FRAAU_RS13040
uniprot id: H8KYH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS13350
gene id: 767434:FRAAU_RS13350
uniprot id: H8KZ10
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

767434:FRAAU RS08120
gene id: 767434:FRAAU_RS08120
uniprot id: H8KY64
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

767434:FRAAU RS05850
gene id: 767434:FRAAU_RS05850
uniprot id: H8L4G5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

767434:FRAAU RS05475
gene id: 767434:FRAAU_RS05475
uniprot id: H8L3X2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

767434:FRAAU RS13855
gene id: 767434:FRAAU_RS13855
uniprot id: H8L0A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

767434:FRAAU RS13065
gene id: 767434:FRAAU_RS13065
uniprot id: H8KYH6
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

767434:FRAAU RS05730
gene id: 767434:FRAAU_RS05730
uniprot id: H8L421
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

767434:FRAAU RS14000
gene id: 767434:FRAAU_RS14000
uniprot id: H8L111
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

767434:FRAAU RS02505
gene id: 767434:FRAAU_RS02505
uniprot id: H8L4S1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

767434:FRAAU RS14575
gene id: 767434:FRAAU_RS14575
uniprot id: H8L224
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

767434:FRAAU RS14080
gene id: 767434:FRAAU_RS14080
uniprot id: H8L127
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

767434:FRAAU RS08710
gene id: 767434:FRAAU_RS08710
uniprot id: H8KYU7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

767434:FRAAU RS01775
gene id: 767434:FRAAU_RS01775
uniprot id: H8L350
names: Similarity
messages: Belongs to the UPF0102 family.

767434:FRAAU RS08515
gene id: 767434:FRAAU_RS08515
uniprot id: H8KYR1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

767434:FRAAU RS02520
gene id: 767434:FRAAU_RS02520
uniprot id: H8L4S4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

767434:FRAAU RS11060
gene id: 767434:FRAAU_RS11060
uniprot id: H8L4Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

767434:FRAAU RS17360
gene id: 767434:FRAAU_RS17360
uniprot id: H8L0L1
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS12275
gene id: 767434:FRAAU_RS12275
uniprot id: H8L6M6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS13700
gene id: 767434:FRAAU_RS13700
uniprot id: H8L074
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS01885
gene id: 767434:FRAAU_RS01885
uniprot id: H8L3R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

767434:FRAAU RS14860
gene id: 767434:FRAAU_RS14860
uniprot id: H8L2X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

767434:FRAAU RS09305
gene id: 767434:FRAAU_RS09305
uniprot id: H8L060
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

767434:FRAAU RS15955
gene id: 767434:FRAAU_RS15955
uniprot id: H8L246
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS03995
gene id: 767434:FRAAU_RS03995
uniprot id: H8KZZ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

767434:FRAAU RS03345
gene id: 767434:FRAAU_RS03345
uniprot id: H8KYM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

767434:FRAAU RS05195
gene id: 767434:FRAAU_RS05195
uniprot id: H8L378
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS11190
gene id: 767434:FRAAU_RS11190
uniprot id: H8L558
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

767434:FRAAU RS02345
gene id: 767434:FRAAU_RS02345
uniprot id: H8L4D0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS11720
gene id: 767434:FRAAU_RS11720
uniprot id: H8L5Z3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

767434:FRAAU RS07735
gene id: 767434:FRAAU_RS07735
uniprot id: H8L6J2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

767434:FRAAU RS12990
gene id: 767434:FRAAU_RS12990
uniprot id: H8KYG3
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell inner membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

767434:FRAAU RS06435
gene id: 767434:FRAAU_RS06435
uniprot id: H8L527
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

767434:FRAAU RS02675
gene id: 767434:FRAAU_RS02675
uniprot id: H8L4V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

767434:FRAAU RS10105
gene id: 767434:FRAAU_RS10105
uniprot id: H8L2R9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

767434:FRAAU RS10380
gene id: 767434:FRAAU_RS10380
uniprot id: H8L3G0
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

767434:FRAAU RS11705
gene id: 767434:FRAAU_RS11705
uniprot id: H8L5Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

767434:FRAAU RS08600
gene id: 767434:FRAAU_RS08600
uniprot id: H8KYS5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

767434:FRAAU RS06825
gene id: 767434:FRAAU_RS06825
uniprot id: H8L5L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS13155
gene id: 767434:FRAAU_RS13155
uniprot id: H8KYX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS02605
gene id: 767434:FRAAU_RS02605
uniprot id: H8L4T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS08170
gene id: 767434:FRAAU_RS08170
uniprot id: H8KY74
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS05210
gene id: 767434:FRAAU_RS05210
uniprot id: H8L381
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

767434:FRAAU RS16515
gene id: 767434:FRAAU_RS16515
uniprot id: H8L1S7
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

767434:FRAAU RS11510
gene id: 767434:FRAAU_RS11510
uniprot id: H8L5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

767434:FRAAU RS15615
gene id: 767434:FRAAU_RS15615
uniprot id: H8L178
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

767434:FRAAU RS00600
gene id: 767434:FRAAU_RS00600
uniprot id: H8L0J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS02980
gene id: 767434:FRAAU_RS02980
uniprot id: H8L5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

767434:FRAAU RS05995
gene id: 767434:FRAAU_RS05995
uniprot id: H8L4J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

767434:FRAAU RS15795
gene id: 767434:FRAAU_RS15795
uniprot id: H8L1B4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS14515
gene id: 767434:FRAAU_RS14515
uniprot id: H8L212
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

767434:FRAAU RS01820
gene id: 767434:FRAAU_RS01820
uniprot id: H8L3Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS12905
gene id: 767434:FRAAU_RS12905
uniprot id: H8KYE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

767434:FRAAU RS00775
gene id: 767434:FRAAU_RS00775
uniprot id: H8L0M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS14090
gene id: 767434:FRAAU_RS14090
uniprot id: H8L129
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS06315
gene id: 767434:FRAAU_RS06315
uniprot id: H8L503
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

767434:FRAAU RS06330
gene id: 767434:FRAAU_RS06330
uniprot id: H8L506
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

767434:FRAAU RS15875
gene id: 767434:FRAAU_RS15875
uniprot id: H8L1C9
names: Similarity
messages: Belongs to the OprB family.

767434:FRAAU RS11970
gene id: 767434:FRAAU_RS11970
uniprot id: H8L6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

767434:FRAAU RS15775
gene id: 767434:FRAAU_RS15775
uniprot id: H8L1B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

767434:FRAAU RS02180
gene id: 767434:FRAAU_RS02180
uniprot id: H8L497
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

767434:FRAAU RS00790
gene id: 767434:FRAAU_RS00790
uniprot id: H8L0N0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

767434:FRAAU RS01810
gene id: 767434:FRAAU_RS01810
uniprot id: H8L357
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS04600
gene id: 767434:FRAAU_RS04600
uniprot id: H8L1P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

767434:FRAAU RS02985
gene id: 767434:FRAAU_RS02985
uniprot id: H8L5C6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

767434:FRAAU RS08595
gene id: 767434:FRAAU_RS08595
uniprot id: H8KYS4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS10465
gene id: 767434:FRAAU_RS10465
uniprot id: H8L3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. AOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-acetyl-L-ornithine to produce N(2)-acetyl-L-citrulline. This is a step in an alternative arginine biosynthesis pathway.
messages: Cytoplasm
messages: Homotrimer.

767434:FRAAU RS11145
gene id: 767434:FRAAU_RS11145
uniprot id: H8L549
names: Similarity
messages: Belongs to the peptidase S9C family.

767434:FRAAU RS02235
gene id: 767434:FRAAU_RS02235
uniprot id: H8L4A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

767434:FRAAU RS10570
gene id: 767434:FRAAU_RS10570
uniprot id: H8L442
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

767434:FRAAU RS11915
gene id: 767434:FRAAU_RS11915
uniprot id: H8L697
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

767434:FRAAU RS04070
gene id: 767434:FRAAU_RS04070
uniprot id: H8L014
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

767434:FRAAU RS15605
gene id: 767434:FRAAU_RS15605
uniprot id: H8L0I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

767434:FRAAU RS09335
gene id: 767434:FRAAU_RS09335
uniprot id: H8L066
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS13100
gene id: 767434:FRAAU_RS13100
uniprot id: H8KYV9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

767434:FRAAU RS10390
gene id: 767434:FRAAU_RS10390
uniprot id: H8L3G2
names: Similarity
messages: Belongs to the MotB family.

767434:FRAAU RS08150
gene id: 767434:FRAAU_RS08150
uniprot id: H8KY70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

767434:FRAAU RS05755
gene id: 767434:FRAAU_RS05755
uniprot id: H8L425
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS15385
gene id: 767434:FRAAU_RS15385
uniprot id: H8L0E5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

767434:FRAAU RS12270
gene id: 767434:FRAAU_RS12270
uniprot id: H8L6M5
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

767434:FRAAU RS12880
gene id: 767434:FRAAU_RS12880
uniprot id: H8KYE2
names: Similarity
messages: Belongs to the pirin family.

767434:FRAAU RS01950
gene id: 767434:FRAAU_RS01950
uniprot id: H8L3T0
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

767434:FRAAU RS08070
gene id: 767434:FRAAU_RS08070
uniprot id: H8L6W2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

767434:FRAAU RS15475
gene id: 767434:FRAAU_RS15475
uniprot id: H8L0G4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS13820
gene id: 767434:FRAAU_RS13820
uniprot id: H8L094
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

767434:FRAAU RS08675
gene id: 767434:FRAAU_RS08675
uniprot id: H8KYU0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

767434:FRAAU RS01280
gene id: 767434:FRAAU_RS01280
uniprot id: H8L2B9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS09600
gene id: 767434:FRAAU_RS09600
uniprot id: H8L108
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

767434:FRAAU RS01425
gene id: 767434:FRAAU_RS01425
uniprot id: H8L2E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

767434:FRAAU RS01010
gene id: 767434:FRAAU_RS01010
uniprot id: H8L1H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

767434:FRAAU RS09430
gene id: 767434:FRAAU_RS09430
uniprot id: H8L0X5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

767434:FRAAU RS07720
gene id: 767434:FRAAU_RS07720
uniprot id: H8L6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

767434:FRAAU RS06285
gene id: 767434:FRAAU_RS06285
uniprot id: H8L4Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

767434:FRAAU RS02835
gene id: 767434:FRAAU_RS02835
uniprot id: H8L599
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

767434:FRAAU RS06795
gene id: 767434:FRAAU_RS06795
uniprot id: H8L5K4
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS14955
gene id: 767434:FRAAU_RS14955
uniprot id: H8L2Z6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

767434:FRAAU RS04260
gene id: 767434:FRAAU_RS04260
uniprot id: H8L0S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

767434:FRAAU RS15690
gene id: 767434:FRAAU_RS15690
uniprot id: H8L193
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS04355
gene id: 767434:FRAAU_RS04355
uniprot id: H8L0U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

767434:FRAAU RS06760
gene id: 767434:FRAAU_RS06760
uniprot id: H8L5J7
names: Similarity
messages: Belongs to the DapA family.

767434:FRAAU RS14150
gene id: 767434:FRAAU_RS14150
uniprot id: H8L141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Periplasm

767434:FRAAU RS10075
gene id: 767434:FRAAU_RS10075
uniprot id: H8L2R3
names: Similarity
messages: Belongs to the elongation factor P family.

767434:FRAAU RS01815
gene id: 767434:FRAAU_RS01815
uniprot id: H8L360
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

767434:FRAAU RS07795
gene id: 767434:FRAAU_RS07795
uniprot id: H8L6L0
names: Similarity
messages: Belongs to the UPF0053 family.

767434:FRAAU RS10100
gene id: 767434:FRAAU_RS10100
uniprot id: H8L2R8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

767434:FRAAU RS13510
gene id: 767434:FRAAU_RS13510
uniprot id: H8KZL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

767434:FRAAU RS02960
gene id: 767434:FRAAU_RS02960
uniprot id: H8L5C2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

767434:FRAAU RS12605
gene id: 767434:FRAAU_RS12605
uniprot id: H8L6Y4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

767434:FRAAU RS02250
gene id: 767434:FRAAU_RS02250
uniprot id: H8L4B1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

767434:FRAAU RS08640
gene id: 767434:FRAAU_RS08640
uniprot id: H8KYT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

767434:FRAAU RS01005
gene id: 767434:FRAAU_RS01005
uniprot id: H8L1H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

767434:FRAAU RS04370
gene id: 767434:FRAAU_RS04370
uniprot id: H8L0U7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

767434:FRAAU RS02655
gene id: 767434:FRAAU_RS02655
uniprot id: H8L4U6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

767434:FRAAU RS02450
gene id: 767434:FRAAU_RS02450
uniprot id: H8L4F0
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS06640
gene id: 767434:FRAAU_RS06640
uniprot id: H8L5H4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

767434:FRAAU RS06660
gene id: 767434:FRAAU_RS06660
uniprot id: H8L5H8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS16445
gene id: 767434:FRAAU_RS16445
uniprot id: H8L6H0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS08400
gene id: 767434:FRAAU_RS08400
uniprot id: H8KYB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

767434:FRAAU RS05080
gene id: 767434:FRAAU_RS05080
uniprot id: H8L2M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS00815
gene id: 767434:FRAAU_RS00815
uniprot id: H8L0N5
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS02575
gene id: 767434:FRAAU_RS02575
uniprot id: H8L4T0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS01700
gene id: 767434:FRAAU_RS01700
uniprot id: H8L337
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

767434:FRAAU RS10585
gene id: 767434:FRAAU_RS10585
uniprot id: H8L444
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS03880
gene id: 767434:FRAAU_RS03880
uniprot id: H8KZX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

767434:FRAAU RS06210
gene id: 767434:FRAAU_RS06210
uniprot id: H8L4Y2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

767434:FRAAU RS11960
gene id: 767434:FRAAU_RS11960
uniprot id: H8L6A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

767434:FRAAU RS04665
gene id: 767434:FRAAU_RS04665
uniprot id: H8L1Q3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS17480
gene id: 767434:FRAAU_RS17480
uniprot id: H8L182
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

767434:FRAAU RS13425
gene id: 767434:FRAAU_RS13425
uniprot id: H8KZJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

767434:FRAAU RS00100
gene id: 767434:FRAAU_RS00100
uniprot id: H8KZ42
names: Similarity
messages: Belongs to the FGGY kinase family.

767434:FRAAU RS09345
gene id: 767434:FRAAU_RS09345
uniprot id: H8L068
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

767434:FRAAU RS14270
gene id: 767434:FRAAU_RS14270
uniprot id: H8L163
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

767434:FRAAU RS11375
gene id: 767434:FRAAU_RS11375
uniprot id: H8L5L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

767434:FRAAU RS10110
gene id: 767434:FRAAU_RS10110
uniprot id: H8L2S0
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

767434:FRAAU RS08615
gene id: 767434:FRAAU_RS08615
uniprot id: H8KYS8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

767434:FRAAU RS04580
gene id: 767434:FRAAU_RS04580
uniprot id: H8L1N5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

767434:FRAAU RS14220
gene id: 767434:FRAAU_RS14220
uniprot id: H8L153
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

767434:FRAAU RS12465
gene id: 767434:FRAAU_RS12465
uniprot id: H8L6R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

767434:FRAAU RS10885
gene id: 767434:FRAAU_RS10885
uniprot id: H8L4M5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

767434:FRAAU RS02300
gene id: 767434:FRAAU_RS02300
uniprot id: H8L4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

767434:FRAAU RS10740
gene id: 767434:FRAAU_RS10740
uniprot id: H8L475
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS00990
gene id: 767434:FRAAU_RS00990
uniprot id: H8L1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

767434:FRAAU RS11485
gene id: 767434:FRAAU_RS11485
uniprot id: H8L5N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

767434:FRAAU RS12475
gene id: 767434:FRAAU_RS12475
uniprot id: H8L6R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

767434:FRAAU RS13790
gene id: 767434:FRAAU_RS13790
uniprot id: H8L087
names: Similarity
messages: Belongs to the RutC family.

767434:FRAAU RS02420
gene id: 767434:FRAAU_RS02420
uniprot id: H8L4E4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

767434:FRAAU RS00250
gene id: 767434:FRAAU_RS00250
uniprot id: H8KZ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

767434:FRAAU RS10010
gene id: 767434:FRAAU_RS10010
uniprot id: H8L2Q0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

767434:FRAAU RS11920
gene id: 767434:FRAAU_RS11920
uniprot id: H8L698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

767434:FRAAU RS09000
gene id: 767434:FRAAU_RS09000
uniprot id: H8KZI2
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

767434:FRAAU RS15305
gene id: 767434:FRAAU_RS15305
uniprot id: H8L0C9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS00170
gene id: 767434:FRAAU_RS00170
uniprot id: H8KZ57
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

767434:FRAAU RS13585
gene id: 767434:FRAAU_RS13585
uniprot id: H8KZM8
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

767434:FRAAU RS07770
gene id: 767434:FRAAU_RS07770
uniprot id: H8L6J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

767434:FRAAU RS13000
gene id: 767434:FRAAU_RS13000
uniprot id: H8KYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS05200
gene id: 767434:FRAAU_RS05200
uniprot id: H8L379
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

767434:FRAAU RS15585
gene id: 767434:FRAAU_RS15585
uniprot id: H8L0I5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

767434:FRAAU RS10440
gene id: 767434:FRAAU_RS10440
uniprot id: H8L3H2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetylcitrulline deacetylase subfamily.
messages: Binds 1 Co(2+) ion per subunit.
messages: Catalyzes the deacetylation of N-acetyl-L-citrulline to produce L-citrulline. This is a step in an alternative arginine biosynthesis pathway.

767434:FRAAU RS13245
gene id: 767434:FRAAU_RS13245
uniprot id: H8KYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS12805
gene id: 767434:FRAAU_RS12805
uniprot id: H8KYC8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

767434:FRAAU RS16095
gene id: 767434:FRAAU_RS16095
uniprot id: H8L273
names: Similarity
messages: Belongs to the glutamine synthetase family.

767434:FRAAU RS12135
gene id: 767434:FRAAU_RS12135
uniprot id: H8L6D9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS01890
gene id: 767434:FRAAU_RS01890
uniprot id: H8L3R8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

767434:FRAAU RS10415
gene id: 767434:FRAAU_RS10415
uniprot id: H8L3G7
names: Similarity
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

767434:FRAAU RS16025
gene id: 767434:FRAAU_RS16025
uniprot id: H8L260
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS02200
gene id: 767434:FRAAU_RS02200
uniprot id: H8L4A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

767434:FRAAU RS16150
gene id: 767434:FRAAU_RS16150
uniprot id: H8L284
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

767434:FRAAU RS07545
gene id: 767434:FRAAU_RS07545
uniprot id: H8L6F4
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

767434:FRAAU RS04125
gene id: 767434:FRAAU_RS04125
uniprot id: H8L0Q1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

767434:FRAAU RS06850
gene id: 767434:FRAAU_RS06850
uniprot id: H8L5R5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

767434:FRAAU RS15960
gene id: 767434:FRAAU_RS15960
uniprot id: H8L247
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

767434:FRAAU RS00465
gene id: 767434:FRAAU_RS00465
uniprot id: H8KZT4
names: Cofactor
messages: Can also use Mn(2+) ion.

767434:FRAAU RS10270
gene id: 767434:FRAAU_RS10270
uniprot id: H8L3D9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

767434:FRAAU RS05910
gene id: 767434:FRAAU_RS05910
uniprot id: H8L4H7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

767434:FRAAU RS14655
gene id: 767434:FRAAU_RS14655
uniprot id: H8L2T9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

767434:FRAAU RS02195
gene id: 767434:FRAAU_RS02195
uniprot id: H8L4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS07670
gene id: 767434:FRAAU_RS07670
uniprot id: H8L6H9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS05825
gene id: 767434:FRAAU_RS05825
uniprot id: H8L4G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

767434:FRAAU RS02290
gene id: 767434:FRAAU_RS02290
uniprot id: H8L4B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

767434:FRAAU RS12955
gene id: 767434:FRAAU_RS12955
uniprot id: H8KYF6
names: Similarity
messages: Belongs to the IucA/IucC family.

767434:FRAAU RS01135
gene id: 767434:FRAAU_RS01135
uniprot id: H8L1J7
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

767434:FRAAU RS01205
gene id: 767434:FRAAU_RS01205
uniprot id: H8L2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

767434:FRAAU RS09650
gene id: 767434:FRAAU_RS09650
uniprot id: H8L1S6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS12125
gene id: 767434:FRAAU_RS12125
uniprot id: H8L6D7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS09315
gene id: 767434:FRAAU_RS09315
uniprot id: H8L062
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

767434:FRAAU RS15675
gene id: 767434:FRAAU_RS15675
uniprot id: H8L190
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

767434:FRAAU RS01285
gene id: 767434:FRAAU_RS01285
uniprot id: H8L2C0
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

767434:FRAAU RS08720
gene id: 767434:FRAAU_RS08720
uniprot id: H8KYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS14375
gene id: 767434:FRAAU_RS14375
uniprot id: H8L1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

767434:FRAAU RS13330
gene id: 767434:FRAAU_RS13330
uniprot id: H8KZ06
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS00530
gene id: 767434:FRAAU_RS00530
uniprot id: H8KZU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

767434:FRAAU RS02700
gene id: 767434:FRAAU_RS02700
uniprot id: H8L4V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

767434:FRAAU RS02935
gene id: 767434:FRAAU_RS02935
uniprot id: H8L5B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

767434:FRAAU RS03560
gene id: 767434:FRAAU_RS03560
uniprot id: H8KZ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

767434:FRAAU RS08580
gene id: 767434:FRAAU_RS08580
uniprot id: H8KYS1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

767434:FRAAU RS09895
gene id: 767434:FRAAU_RS09895
uniprot id: H8L1X2
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS13105
gene id: 767434:FRAAU_RS13105
uniprot id: H8KYW0
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS10805
gene id: 767434:FRAAU_RS10805
uniprot id: H8L488
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

767434:FRAAU RS14190
gene id: 767434:FRAAU_RS14190
uniprot id: H8L147
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

767434:FRAAU RS01645
gene id: 767434:FRAAU_RS01645
uniprot id: H8L326
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

767434:FRAAU RS15780
gene id: 767434:FRAAU_RS15780
uniprot id: H8L1B1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

767434:FRAAU RS02145
gene id: 767434:FRAAU_RS02145
uniprot id: H8L3W5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

767434:FRAAU RS15030
gene id: 767434:FRAAU_RS15030
uniprot id: H8L3K1
names: Similarity
messages: Belongs to the allantoicase family.

767434:FRAAU RS12930
gene id: 767434:FRAAU_RS12930
uniprot id: H8KYF1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

767434:FRAAU RS08045
gene id: 767434:FRAAU_RS08045
uniprot id: H8L6V7
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS00085
gene id: 767434:FRAAU_RS00085
uniprot id: H8KZ38
names: Similarity
messages: Belongs to the peptidase S9C family.

767434:FRAAU RS15740
gene id: 767434:FRAAU_RS15740
uniprot id: H8L1A2
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS04120
gene id: 767434:FRAAU_RS04120
uniprot id: H8L0Q0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

767434:FRAAU RS01640
gene id: 767434:FRAAU_RS01640
uniprot id: H8L325
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS13005
gene id: 767434:FRAAU_RS13005
uniprot id: H8KYG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

767434:FRAAU RS02800
gene id: 767434:FRAAU_RS02800
uniprot id: H8L592
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

767434:FRAAU RS10970
gene id: 767434:FRAAU_RS10970
uniprot id: H8L4P0
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

767434:FRAAU RS16500
gene id: 767434:FRAAU_RS16500
uniprot id: H8KZF3
names: Similarity
messages: Belongs to the VgrG protein family.

767434:FRAAU RS03160
gene id: 767434:FRAAU_RS03160
uniprot id: H8KYI5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS15405
gene id: 767434:FRAAU_RS15405
uniprot id: H8L0E8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

767434:FRAAU RS11530
gene id: 767434:FRAAU_RS11530
uniprot id: H8L5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS14830
gene id: 767434:FRAAU_RS14830
uniprot id: H8L2X2
names: Similarity
messages: Belongs to the glutamate synthase family.

767434:FRAAU RS03685
gene id: 767434:FRAAU_RS03685
uniprot id: H8KZB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

767434:FRAAU RS11875
gene id: 767434:FRAAU_RS11875
uniprot id: H8L623
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

767434:FRAAU RS08445
gene id: 767434:FRAAU_RS08445
uniprot id: H8KYP7
names: Similarity
messages: Belongs to the BolA/IbaG family.

767434:FRAAU RS00485
gene id: 767434:FRAAU_RS00485
uniprot id: H8KZT8
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

767434:FRAAU RS10200
gene id: 767434:FRAAU_RS10200
uniprot id: H8L2T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

767434:FRAAU RS06980
gene id: 767434:FRAAU_RS06980
uniprot id: H8L5U1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

767434:FRAAU RS11750
gene id: 767434:FRAAU_RS11750
uniprot id: H8L5Z8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

767434:FRAAU RS01310
gene id: 767434:FRAAU_RS01310
uniprot id: H8L2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

767434:FRAAU RS14675
gene id: 767434:FRAAU_RS14675
uniprot id: H8L2U3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

767434:FRAAU RS06585
gene id: 767434:FRAAU_RS06585
uniprot id: H8L5G4
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

767434:FRAAU RS01395
gene id: 767434:FRAAU_RS01395
uniprot id: H8L2E2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

767434:FRAAU RS08165
gene id: 767434:FRAAU_RS08165
uniprot id: H8KY73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

767434:FRAAU RS10245
gene id: 767434:FRAAU_RS10245
uniprot id: H8L3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

767434:FRAAU RS02500
gene id: 767434:FRAAU_RS02500
uniprot id: H8L4S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

767434:FRAAU RS13415
gene id: 767434:FRAAU_RS13415
uniprot id: H8KZJ3
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

767434:FRAAU RS01630
gene id: 767434:FRAAU_RS01630
uniprot id: H8L323
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

767434:FRAAU RS15695
gene id: 767434:FRAAU_RS15695
uniprot id: H8L194
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS01755
gene id: 767434:FRAAU_RS01755
uniprot id: H8L346
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

767434:FRAAU RS03305
gene id: 767434:FRAAU_RS03305
uniprot id: H8KYL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

767434:FRAAU RS06665
gene id: 767434:FRAAU_RS06665
uniprot id: H8L5H9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

767434:FRAAU RS08265
gene id: 767434:FRAAU_RS08265
uniprot id: H8KY93
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

767434:FRAAU RS02870
gene id: 767434:FRAAU_RS02870
uniprot id: H8L5A6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

767434:FRAAU RS11350
gene id: 767434:FRAAU_RS11350
uniprot id: H8L585
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

767434:FRAAU RS09470
gene id: 767434:FRAAU_RS09470
uniprot id: H8L0Y3
names: Similarity
messages: Belongs to the RutC family.

767434:FRAAU RS08345
gene id: 767434:FRAAU_RS08345
uniprot id: H8KYA7
names: Subcellular Location Annotation
messages: Cytoplasm

767434:FRAAU RS02705
gene id: 767434:FRAAU_RS02705
uniprot id: H8L4V6
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

767434:FRAAU RS05530
gene id: 767434:FRAAU_RS05530
uniprot id: H8L3Y2
names: Similarity
messages: Belongs to the PhzF family.

767434:FRAAU RS03800
gene id: 767434:FRAAU_RS03800
uniprot id: H8KZW1
names: Similarity
messages: Belongs to the thioredoxin family.

767434:FRAAU RS08040
gene id: 767434:FRAAU_RS08040
uniprot id: H8L6V6
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

767434:FRAAU RS03550
gene id: 767434:FRAAU_RS03550
uniprot id: H8KZ89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

767434:FRAAU RS07575
gene id: 767434:FRAAU_RS07575
uniprot id: H8L6G0
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS12100
gene id: 767434:FRAAU_RS12100
uniprot id: H8L6D2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

767434:FRAAU RS01845
gene id: 767434:FRAAU_RS01845
uniprot id: H8L3Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

767434:FRAAU RS04225
gene id: 767434:FRAAU_RS04225
uniprot id: H8L0S1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

767434:FRAAU RS03640
gene id: 767434:FRAAU_RS03640
uniprot id: H8KZA7
names: Subcellular Location Annotation
messages: Cytoplasm

767434:FRAAU RS02005
gene id: 767434:FRAAU_RS02005
uniprot id: H8L3U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

767434:FRAAU RS09145
gene id: 767434:FRAAU_RS09145
uniprot id: H8L038
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

767434:FRAAU RS14495
gene id: 767434:FRAAU_RS14495
uniprot id: H8L208
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

767434:FRAAU RS00960
gene id: 767434:FRAAU_RS00960
uniprot id: H8L1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

767434:FRAAU RS00315
gene id: 767434:FRAAU_RS00315
uniprot id: H8KZQ4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

767434:FRAAU RS13460
gene id: 767434:FRAAU_RS13460
uniprot id: H8KZK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS13650
gene id: 767434:FRAAU_RS13650
uniprot id: H8KZP1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

767434:FRAAU RS04650
gene id: 767434:FRAAU_RS04650
uniprot id: H8L1Q0
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

767434:FRAAU RS03150
gene id: 767434:FRAAU_RS03150
uniprot id: H8KYI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

767434:FRAAU RS02215
gene id: 767434:FRAAU_RS02215
uniprot id: H8L4A4
names: Similarity
messages: Belongs to the nitroreductase family.

767434:FRAAU RS02740
gene id: 767434:FRAAU_RS02740
uniprot id: H8L4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

767434:FRAAU RS06970
gene id: 767434:FRAAU_RS06970
uniprot id: H8L5T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

767434:FRAAU RS10765
gene id: 767434:FRAAU_RS10765
uniprot id: H8L480
names: Similarity
messages: Belongs to the TrpC family.

767434:FRAAU RS15765
gene id: 767434:FRAAU_RS15765
uniprot id: H8L1A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

767434:FRAAU RS03330
gene id: 767434:FRAAU_RS03330
uniprot id: H8KYM0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

767434:FRAAU RS10210
gene id: 767434:FRAAU_RS10210
uniprot id: H8L3C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

767434:FRAAU RS08735
gene id: 767434:FRAAU_RS08735
uniprot id: H8KYU9
names: Similarity
messages: Belongs to the YjdM family.

767434:FRAAU RS08630
gene id: 767434:FRAAU_RS08630
uniprot id: H8KYT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

767434:FRAAU RS04435
gene id: 767434:FRAAU_RS04435
uniprot id: H8L1K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

767434:FRAAU RS15980
gene id: 767434:FRAAU_RS15980
uniprot id: H8L251
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS08290
gene id: 767434:FRAAU_RS08290
uniprot id: H8KY98
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

767434:FRAAU RS02155
gene id: 767434:FRAAU_RS02155
uniprot id: H8L492
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

767434:FRAAU RS03810
gene id: 767434:FRAAU_RS03810
uniprot id: H8KZW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

767434:FRAAU RS01980
gene id: 767434:FRAAU_RS01980
uniprot id: H8L3T7
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

767434:FRAAU RS03860
gene id: 767434:FRAAU_RS03860
uniprot id: H8KZX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

767434:FRAAU RS09875
gene id: 767434:FRAAU_RS09875
uniprot id: H8L1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

767434:FRAAU RS12595
gene id: 767434:FRAAU_RS12595
uniprot id: H8L6Y2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

767434:FRAAU RS10180
gene id: 767434:FRAAU_RS10180
uniprot id: H8L2T6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

767434:FRAAU RS00945
gene id: 767434:FRAAU_RS00945
uniprot id: H8L1F9
names: Similarity
messages: Belongs to the peptidase A24 family.

767434:FRAAU RS13890
gene id: 767434:FRAAU_RS13890
uniprot id: H8L0A8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

767434:FRAAU RS06000
gene id: 767434:FRAAU_RS06000
uniprot id: H8L4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

767434:FRAAU RS03695
gene id: 767434:FRAAU_RS03695
uniprot id: H8KZB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

767434:FRAAU RS03340
gene id: 767434:FRAAU_RS03340
uniprot id: H8KYM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

767434:FRAAU RS14265
gene id: 767434:FRAAU_RS14265
uniprot id: H8L162
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

767434:FRAAU RS03805
gene id: 767434:FRAAU_RS03805
uniprot id: H8KZW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

767434:FRAAU RS09440
gene id: 767434:FRAAU_RS09440
uniprot id: H8L0X7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS07995
gene id: 767434:FRAAU_RS07995
uniprot id: H8L6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS02875
gene id: 767434:FRAAU_RS02875
uniprot id: H8L5A7
names: Similarity
messages: Belongs to the UPF0250 family.

767434:FRAAU RS16010
gene id: 767434:FRAAU_RS16010
uniprot id: H8L257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

767434:FRAAU RS03260
gene id: 767434:FRAAU_RS03260
uniprot id: H8KYK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

767434:FRAAU RS14140
gene id: 767434:FRAAU_RS14140
uniprot id: H8L139
names: Similarity
messages: Belongs to the phosphohexose mutase family.

767434:FRAAU RS05695
gene id: 767434:FRAAU_RS05695
uniprot id: H8L414
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS09510
gene id: 767434:FRAAU_RS09510
uniprot id: H8L0Z1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

767434:FRAAU RS03475
gene id: 767434:FRAAU_RS03475
uniprot id: H8KZ73
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

767434:FRAAU RS06695
gene id: 767434:FRAAU_RS06695
uniprot id: H8L5I5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

767434:FRAAU RS01735
gene id: 767434:FRAAU_RS01735
uniprot id: H8L358
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

767434:FRAAU RS04145
gene id: 767434:FRAAU_RS04145
uniprot id: H8L0Q5
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS06395
gene id: 767434:FRAAU_RS06395
uniprot id: H8L519
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

767434:FRAAU RS12365
gene id: 767434:FRAAU_RS12365
uniprot id: H8L6P1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

767434:FRAAU RS01305
gene id: 767434:FRAAU_RS01305
uniprot id: H8L2C4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

767434:FRAAU RS03505
gene id: 767434:FRAAU_RS03505
uniprot id: H8KZ80
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

767434:FRAAU RS10250
gene id: 767434:FRAAU_RS10250
uniprot id: H8L3D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

767434:FRAAU RS00615
gene id: 767434:FRAAU_RS00615
uniprot id: H8L0J7
names: Similarity
messages: Belongs to the universal stress protein A family.

767434:FRAAU RS15885
gene id: 767434:FRAAU_RS15885
uniprot id: H8L1D1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

767434:FRAAU RS09845
gene id: 767434:FRAAU_RS09845
uniprot id: H8L1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

767434:FRAAU RS06615
gene id: 767434:FRAAU_RS06615
uniprot id: H8L5G9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

767434:FRAAU RS06465
gene id: 767434:FRAAU_RS06465
uniprot id: H8L532
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS14500
gene id: 767434:FRAAU_RS14500
uniprot id: H8L209
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS09425
gene id: 767434:FRAAU_RS09425
uniprot id: H8L0X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

767434:FRAAU RS01745
gene id: 767434:FRAAU_RS01745
uniprot id: H8L344
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

767434:FRAAU RS11775
gene id: 767434:FRAAU_RS11775
uniprot id: H8L602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS16030
gene id: 767434:FRAAU_RS16030
uniprot id: H8L261
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

767434:FRAAU RS11245
gene id: 767434:FRAAU_RS11245
uniprot id: H8L568
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS04185
gene id: 767434:FRAAU_RS04185
uniprot id: H8L0R3
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

767434:FRAAU RS10510
gene id: 767434:FRAAU_RS10510
uniprot id: H8L3I2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

767434:FRAAU RS10670
gene id: 767434:FRAAU_RS10670
uniprot id: H8L460
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

767434:FRAAU RS06990
gene id: 767434:FRAAU_RS06990
uniprot id: H8L5U3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

767434:FRAAU RS14450
gene id: 767434:FRAAU_RS14450
uniprot id: H8L1Z8
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS10060
gene id: 767434:FRAAU_RS10060
uniprot id: H8L2R0
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS00035
gene id: 767434:FRAAU_RS00035
uniprot id: H8KZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

767434:FRAAU RS02060
gene id: 767434:FRAAU_RS02060
uniprot id: H8L3V2
names: Similarity
messages: Belongs to the MlaA family.

767434:FRAAU RS03275
gene id: 767434:FRAAU_RS03275
uniprot id: H8KYK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

767434:FRAAU RS15160
gene id: 767434:FRAAU_RS15160
uniprot id: H8L3M7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

767434:FRAAU RS00700
gene id: 767434:FRAAU_RS00700
uniprot id: H8L0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Membrane

767434:FRAAU RS13395
gene id: 767434:FRAAU_RS13395
uniprot id: H8KZ19
names: Similarity
messages: Belongs to the peptidase S49 family.

767434:FRAAU RS09670
gene id: 767434:FRAAU_RS09670
uniprot id: H8L1T0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS01905
gene id: 767434:FRAAU_RS01905
uniprot id: H8L3S1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

767434:FRAAU RS10015
gene id: 767434:FRAAU_RS10015
uniprot id: H8L2Q1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

767434:FRAAU RS09265
gene id: 767434:FRAAU_RS09265
uniprot id: H8L052
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

767434:FRAAU RS06115
gene id: 767434:FRAAU_RS06115
uniprot id: H8L4K5
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS03950
gene id: 767434:FRAAU_RS03950
uniprot id: H8KZY9
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

767434:FRAAU RS09125
gene id: 767434:FRAAU_RS09125
uniprot id: H8L034
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS07560
gene id: 767434:FRAAU_RS07560
uniprot id: H8L6F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

767434:FRAAU RS15965
gene id: 767434:FRAAU_RS15965
uniprot id: H8L248
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

767434:FRAAU RS11140
gene id: 767434:FRAAU_RS11140
uniprot id: H8L548
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

767434:FRAAU RS09665
gene id: 767434:FRAAU_RS09665
uniprot id: H8L1S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

767434:FRAAU RS13020
gene id: 767434:FRAAU_RS13020
uniprot id: H8KYG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

767434:FRAAU RS13735
gene id: 767434:FRAAU_RS13735
uniprot id: H8L076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS08605
gene id: 767434:FRAAU_RS08605
uniprot id: H8KYS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

767434:FRAAU RS06790
gene id: 767434:FRAAU_RS06790
uniprot id: H8L5K3
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

767434:FRAAU RS05215
gene id: 767434:FRAAU_RS05215
uniprot id: H8L382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

767434:FRAAU RS01045
gene id: 767434:FRAAU_RS01045
uniprot id: H8L1H9
names: Similarity
messages: Belongs to the OprB family.

767434:FRAAU RS07740
gene id: 767434:FRAAU_RS07740
uniprot id: H8L6J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS14445
gene id: 767434:FRAAU_RS14445
uniprot id: H8L1Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS01915
gene id: 767434:FRAAU_RS01915
uniprot id: H8L3S3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

767434:FRAAU RS13690
gene id: 767434:FRAAU_RS13690
uniprot id: H8L072
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

767434:FRAAU RS03545
gene id: 767434:FRAAU_RS03545
uniprot id: H8KZ88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

767434:FRAAU RS01345
gene id: 767434:FRAAU_RS01345
uniprot id: H8L2D2
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

767434:FRAAU RS02650
gene id: 767434:FRAAU_RS02650
uniprot id: H8L4U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

767434:FRAAU RS14225
gene id: 767434:FRAAU_RS14225
uniprot id: H8L154
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

767434:FRAAU RS11780
gene id: 767434:FRAAU_RS11780
uniprot id: H8L603
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS10315
gene id: 767434:FRAAU_RS10315
uniprot id: H8L3E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

767434:FRAAU RS08450
gene id: 767434:FRAAU_RS08450
uniprot id: H8KYP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

767434:FRAAU RS02855
gene id: 767434:FRAAU_RS02855
uniprot id: H8L5A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

767434:FRAAU RS16125
gene id: 767434:FRAAU_RS16125
uniprot id: H8L279
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS14895
gene id: 767434:FRAAU_RS14895
uniprot id: H8L2Y6
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS12115
gene id: 767434:FRAAU_RS12115
uniprot id: H8L6D5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

767434:FRAAU RS09515
gene id: 767434:FRAAU_RS09515
uniprot id: H8L0Z2
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

767434:FRAAU RS03390
gene id: 767434:FRAAU_RS03390
uniprot id: H8KYN2
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

767434:FRAAU RS02065
gene id: 767434:FRAAU_RS02065
uniprot id: H8L3V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

767434:FRAAU RS10645
gene id: 767434:FRAAU_RS10645
uniprot id: H8L455
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

767434:FRAAU RS13140
gene id: 767434:FRAAU_RS13140
uniprot id: H8KYW8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

767434:FRAAU RS05870
gene id: 767434:FRAAU_RS05870
uniprot id: H8L4G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS14425
gene id: 767434:FRAAU_RS14425
uniprot id: H8L1Z3
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

767434:FRAAU RS09460
gene id: 767434:FRAAU_RS09460
uniprot id: H8L0Y1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

767434:FRAAU RS01035
gene id: 767434:FRAAU_RS01035
uniprot id: H8L1H7
names: Similarity
messages: Belongs to the peptidase M16 family.

767434:FRAAU RS15250
gene id: 767434:FRAAU_RS15250
uniprot id: H8L3P4
names: Similarity
messages: Belongs to the pirin family.

767434:FRAAU RS08000
gene id: 767434:FRAAU_RS08000
uniprot id: H8L6U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS04345
gene id: 767434:FRAAU_RS04345
uniprot id: H8L0U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS11065
gene id: 767434:FRAAU_RS11065
uniprot id: H8L4Q7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

767434:FRAAU RS02845
gene id: 767434:FRAAU_RS02845
uniprot id: H8L5A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

767434:FRAAU RS13420
gene id: 767434:FRAAU_RS13420
uniprot id: H8KZJ4
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.

767434:FRAAU RS10680
gene id: 767434:FRAAU_RS10680
uniprot id: H8L462
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

767434:FRAAU RS15205
gene id: 767434:FRAAU_RS15205
uniprot id: H8L3N5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

767434:FRAAU RS10000
gene id: 767434:FRAAU_RS10000
uniprot id: H8L2P8
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

767434:FRAAU RS15560
gene id: 767434:FRAAU_RS15560
uniprot id: H8L0I0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

767434:FRAAU RS04135
gene id: 767434:FRAAU_RS04135
uniprot id: H8L0Q3
names: Similarity
messages: Belongs to the universal stress protein A family.

767434:FRAAU RS12975
gene id: 767434:FRAAU_RS12975
uniprot id: H8KYG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

767434:FRAAU RS12645
gene id: 767434:FRAAU_RS12645
uniprot id: H8L6Z1
names: Similarity
messages: Belongs to the PhoH family.

767434:FRAAU RS02635
gene id: 767434:FRAAU_RS02635
uniprot id: H8L4U2
names: Similarity
messages: Belongs to the catalase family.

767434:FRAAU RS03470
gene id: 767434:FRAAU_RS03470
uniprot id: H8KZ72
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

767434:FRAAU RS01550
gene id: 767434:FRAAU_RS01550
uniprot id: H8L307
names: Similarity
messages: Belongs to the KdgT transporter family.

767434:FRAAU RS01705
gene id: 767434:FRAAU_RS01705
uniprot id: H8L338
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

767434:FRAAU RS01115
gene id: 767434:FRAAU_RS01115
uniprot id: H8L1J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

767434:FRAAU RS06645
gene id: 767434:FRAAU_RS06645
uniprot id: H8L5H5
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS01465
gene id: 767434:FRAAU_RS01465
uniprot id: H8L2F3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS13555
gene id: 767434:FRAAU_RS13555
uniprot id: H8KZM1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS04520
gene id: 767434:FRAAU_RS04520
uniprot id: H8L1M3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS11595
gene id: 767434:FRAAU_RS11595
uniprot id: H8L5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS02225
gene id: 767434:FRAAU_RS02225
uniprot id: H8L4A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

767434:FRAAU RS07920
gene id: 767434:FRAAU_RS07920
uniprot id: H8L6T2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

767434:FRAAU RS07990
gene id: 767434:FRAAU_RS07990
uniprot id: H8L6U6
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS07835
gene id: 767434:FRAAU_RS07835
uniprot id: H8L6R5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS00980
gene id: 767434:FRAAU_RS00980
uniprot id: H8L1G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

767434:FRAAU RS16015
gene id: 767434:FRAAU_RS16015
uniprot id: H8L258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

767434:FRAAU RS15225
gene id: 767434:FRAAU_RS15225
uniprot id: H8L3N9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

767434:FRAAU RS14750
gene id: 767434:FRAAU_RS14750
uniprot id: H8L2V8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS06680
gene id: 767434:FRAAU_RS06680
uniprot id: H8L5I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

767434:FRAAU RS00850
gene id: 767434:FRAAU_RS00850
uniprot id: H8L0P2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

767434:FRAAU RS10195
gene id: 767434:FRAAU_RS10195
uniprot id: H8L2T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

767434:FRAAU RS10475
gene id: 767434:FRAAU_RS10475
uniprot id: H8L3I3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

767434:FRAAU RS14020
gene id: 767434:FRAAU_RS14020
uniprot id: H8L115
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

767434:FRAAU RS08285
gene id: 767434:FRAAU_RS08285
uniprot id: H8KY97
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

767434:FRAAU RS12060
gene id: 767434:FRAAU_RS12060
uniprot id: H8L6C5
names: Similarity
messages: Belongs to the ArsC family.

767434:FRAAU RS01695
gene id: 767434:FRAAU_RS01695
uniprot id: H8L336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

767434:FRAAU RS03000
gene id: 767434:FRAAU_RS03000
uniprot id: H8L5D0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

767434:FRAAU RS01610
gene id: 767434:FRAAU_RS01610
uniprot id: H8L319
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS03895
gene id: 767434:FRAAU_RS03895
uniprot id: H8KZY0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

767434:FRAAU RS10215
gene id: 767434:FRAAU_RS10215
uniprot id: H8L3C8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

767434:FRAAU RS11405
gene id: 767434:FRAAU_RS11405
uniprot id: H8L5M0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

767434:FRAAU RS01850
gene id: 767434:FRAAU_RS01850
uniprot id: H8L3R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

767434:FRAAU RS14110
gene id: 767434:FRAAU_RS14110
uniprot id: H8L133
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

767434:FRAAU RS11895
gene id: 767434:FRAAU_RS11895
uniprot id: H8L629
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

767434:FRAAU RS00260
gene id: 767434:FRAAU_RS00260
uniprot id: H8KZ64
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS14600
gene id: 767434:FRAAU_RS14600
uniprot id: H8L227
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

767434:FRAAU RS00875
gene id: 767434:FRAAU_RS00875
uniprot id: H8L1E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

767434:FRAAU RS10240
gene id: 767434:FRAAU_RS10240
uniprot id: H8L3D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

767434:FRAAU RS05710
gene id: 767434:FRAAU_RS05710
uniprot id: H8L417
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

767434:FRAAU RS01100
gene id: 767434:FRAAU_RS01100
uniprot id: H8L1J0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

767434:FRAAU RS08905
gene id: 767434:FRAAU_RS08905
uniprot id: H8KZG3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

767434:FRAAU RS05935
gene id: 767434:FRAAU_RS05935
uniprot id: H8L4I1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

767434:FRAAU RS12710
gene id: 767434:FRAAU_RS12710
uniprot id: H8L705
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

767434:FRAAU RS09330
gene id: 767434:FRAAU_RS09330
uniprot id: H8L065
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

767434:FRAAU RS05120
gene id: 767434:FRAAU_RS05120
uniprot id: H8L363
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

767434:FRAAU RS03875
gene id: 767434:FRAAU_RS03875
uniprot id: H8KZX6
names: Similarity
messages: Belongs to the WrbA family.

767434:FRAAU RS06910
gene id: 767434:FRAAU_RS06910
uniprot id: H8L5S7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

767434:FRAAU RS10725
gene id: 767434:FRAAU_RS10725
uniprot id: H8L472
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

767434:FRAAU RS15505
gene id: 767434:FRAAU_RS15505
uniprot id: H8L0H0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS11400
gene id: 767434:FRAAU_RS11400
uniprot id: H8L5L9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS01410
gene id: 767434:FRAAU_RS01410
uniprot id: H8L2E5
names: Subunit
messages: Monomer. Interacts with PqqE.

767434:FRAAU RS00255
gene id: 767434:FRAAU_RS00255
uniprot id: H8KZ63
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

767434:FRAAU RS05410
gene id: 767434:FRAAU_RS05410
uniprot id: H8L3B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

767434:FRAAU RS03670
gene id: 767434:FRAAU_RS03670
uniprot id: H8KZB3
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.

767434:FRAAU RS10230
gene id: 767434:FRAAU_RS10230
uniprot id: H8L3D1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS08340
gene id: 767434:FRAAU_RS08340
uniprot id: H8KYA6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS11810
gene id: 767434:FRAAU_RS11810
uniprot id: H8L610
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS13500
gene id: 767434:FRAAU_RS13500
uniprot id: H8KZL0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

767434:FRAAU RS13260
gene id: 767434:FRAAU_RS13260
uniprot id: H8KYZ2
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS03165
gene id: 767434:FRAAU_RS03165
uniprot id: H8KYI6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

767434:FRAAU RS03600
gene id: 767434:FRAAU_RS03600
uniprot id: H8KZ99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

767434:FRAAU RS15940
gene id: 767434:FRAAU_RS15940
uniprot id: H8L243
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS08645
gene id: 767434:FRAAU_RS08645
uniprot id: H8KYT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

767434:FRAAU RS09300
gene id: 767434:FRAAU_RS09300
uniprot id: H8L059
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

767434:FRAAU RS15805
gene id: 767434:FRAAU_RS15805
uniprot id: H8L1B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

767434:FRAAU RS03350
gene id: 767434:FRAAU_RS03350
uniprot id: H8KYM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

767434:FRAAU RS00930
gene id: 767434:FRAAU_RS00930
uniprot id: H8L1F6
names: Similarity
messages: Belongs to the bacterial secretin family.

767434:FRAAU RS04465
gene id: 767434:FRAAU_RS04465
uniprot id: H8L1L2
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

767434:FRAAU RS06840
gene id: 767434:FRAAU_RS06840
uniprot id: H8L5R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

767434:FRAAU RS06905
gene id: 767434:FRAAU_RS06905
uniprot id: H8L5S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

767434:FRAAU RS09535
gene id: 767434:FRAAU_RS09535
uniprot id: H8L0Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

767434:FRAAU RS01025
gene id: 767434:FRAAU_RS01025
uniprot id: H8L1H5
names: Similarity
messages: Belongs to the pirin family.

767434:FRAAU RS14380
gene id: 767434:FRAAU_RS14380
uniprot id: H8L1Y4
names: Similarity
messages: Belongs to the UPF0047 family.

767434:FRAAU RS09840
gene id: 767434:FRAAU_RS09840
uniprot id: H8L1W5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

767434:FRAAU RS02360
gene id: 767434:FRAAU_RS02360
uniprot id: H8L4D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS07525
gene id: 767434:FRAAU_RS07525
uniprot id: H8L695
names: Similarity
messages: Belongs to the Skp family.

767434:FRAAU RS00355
gene id: 767434:FRAAU_RS00355
uniprot id: H8KZR2
names: Similarity
messages: Belongs to the aldose epimerase family.

767434:FRAAU RS02425
gene id: 767434:FRAAU_RS02425
uniprot id: H8L4E5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

767434:FRAAU RS14730
gene id: 767434:FRAAU_RS14730
uniprot id: H8L2V4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

767434:FRAAU RS01180
gene id: 767434:FRAAU_RS01180
uniprot id: H8L2A0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

767434:FRAAU RS16570
gene id: 767434:FRAAU_RS16570
uniprot id: H8L586
names: Similarity
messages: Belongs to the polypeptide deformylase family.

767434:FRAAU RS02000
gene id: 767434:FRAAU_RS02000
uniprot id: H8L3U1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

767434:FRAAU RS06420
gene id: 767434:FRAAU_RS06420
uniprot id: H8L524
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

767434:FRAAU RS15790
gene id: 767434:FRAAU_RS15790
uniprot id: H8L1B3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

767434:FRAAU RS06935
gene id: 767434:FRAAU_RS06935
uniprot id: H8L5T2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

767434:FRAAU RS03525
gene id: 767434:FRAAU_RS03525
uniprot id: H8KZ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

767434:FRAAU RS09365
gene id: 767434:FRAAU_RS09365
uniprot id: H8L0W4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

767434:FRAAU RS11880
gene id: 767434:FRAAU_RS11880
uniprot id: H8L624
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

767434:FRAAU RS05590
gene id: 767434:FRAAU_RS05590
uniprot id: H8L3Z4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

767434:FRAAU RS06630
gene id: 767434:FRAAU_RS06630
uniprot id: H8L5H2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

767434:FRAAU RS07015
gene id: 767434:FRAAU_RS07015
uniprot id: H8L5U8
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS14885
gene id: 767434:FRAAU_RS14885
uniprot id: H8L2Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

767434:FRAAU RS16120
gene id: 767434:FRAAU_RS16120
uniprot id: H8L278
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

767434:FRAAU RS13130
gene id: 767434:FRAAU_RS13130
uniprot id: H8KYW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

767434:FRAAU RS10655
gene id: 767434:FRAAU_RS10655
uniprot id: H8L457
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

767434:FRAAU RS03925
gene id: 767434:FRAAU_RS03925
uniprot id: H8KZY5
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS15295
gene id: 767434:FRAAU_RS15295
uniprot id: H8L3Q3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

767434:FRAAU RS05250
gene id: 767434:FRAAU_RS05250
uniprot id: H8L389
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

767434:FRAAU RS04485
gene id: 767434:FRAAU_RS04485
uniprot id: H8L1L6
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS08250
gene id: 767434:FRAAU_RS08250
uniprot id: H8KY90
names: Similarity
messages: Belongs to the LOG family.

767434:FRAAU RS02165
gene id: 767434:FRAAU_RS02165
uniprot id: H8L494
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

767434:FRAAU RS04325
gene id: 767434:FRAAU_RS04325
uniprot id: H8L0T9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

767434:FRAAU RS11600
gene id: 767434:FRAAU_RS11600
uniprot id: H8L5Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

767434:FRAAU RS09295
gene id: 767434:FRAAU_RS09295
uniprot id: H8L058
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

767434:FRAAU RS01925
gene id: 767434:FRAAU_RS01925
uniprot id: H8L3S5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

767434:FRAAU RS07005
gene id: 767434:FRAAU_RS07005
uniprot id: H8L5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

767434:FRAAU RS14145
gene id: 767434:FRAAU_RS14145
uniprot id: H8L140
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Membrane

767434:FRAAU RS03315
gene id: 767434:FRAAU_RS03315
uniprot id: H8KYL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

767434:FRAAU RS04170
gene id: 767434:FRAAU_RS04170
uniprot id: H8L0R0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

767434:FRAAU RS10145
gene id: 767434:FRAAU_RS10145
uniprot id: H8L2S7
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

767434:FRAAU RS11925
gene id: 767434:FRAAU_RS11925
uniprot id: H8L699
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

767434:FRAAU RS04585
gene id: 767434:FRAAU_RS04585
uniprot id: H8L1N6
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS05185
gene id: 767434:FRAAU_RS05185
uniprot id: H8L376
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

767434:FRAAU RS01110
gene id: 767434:FRAAU_RS01110
uniprot id: H8L1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

767434:FRAAU RS04570
gene id: 767434:FRAAU_RS04570
uniprot id: H8L1N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

767434:FRAAU RS13635
gene id: 767434:FRAAU_RS13635
uniprot id: H8KZN8
names: Subcellular Location Annotation
messages: Membrane

767434:FRAAU RS13775
gene id: 767434:FRAAU_RS13775
uniprot id: H8L084
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

767434:FRAAU RS01800
gene id: 767434:FRAAU_RS01800
uniprot id: H8L355
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

767434:FRAAU RS14695
gene id: 767434:FRAAU_RS14695
uniprot id: H8L2U7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

767434:FRAAU RS10810
gene id: 767434:FRAAU_RS10810
uniprot id: H8L489
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

767434:FRAAU RS06060
gene id: 767434:FRAAU_RS06060
uniprot id: H8L4J8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

767434:FRAAU RS09550
gene id: 767434:FRAAU_RS09550
uniprot id: H8L0Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

767434:FRAAU RS05420
gene id: 767434:FRAAU_RS05420
uniprot id: H8L3B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

767434:FRAAU RS04215
gene id: 767434:FRAAU_RS04215
uniprot id: H8L0R9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

767434:FRAAU RS00825
gene id: 767434:FRAAU_RS00825
uniprot id: H8L0N7
names: Similarity
messages: Belongs to the peptidase M1 family.

767434:FRAAU RS02840
gene id: 767434:FRAAU_RS02840
uniprot id: H8L5A0
names: Similarity
messages: Belongs to the MreC family.

767434:FRAAU RS15430
gene id: 767434:FRAAU_RS15430
uniprot id: H8L0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

767434:FRAAU RS10815
gene id: 767434:FRAAU_RS10815
uniprot id: H8L4L1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

767434:FRAAU RS14175
gene id: 767434:FRAAU_RS14175
uniprot id: H8L144
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS13965
gene id: 767434:FRAAU_RS13965
uniprot id: H8L0B9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

767434:FRAAU RS02955
gene id: 767434:FRAAU_RS02955
uniprot id: H8L5C1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

767434:FRAAU RS10005
gene id: 767434:FRAAU_RS10005
uniprot id: H8L2P9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

767434:FRAAU RS03520
gene id: 767434:FRAAU_RS03520
uniprot id: H8KZ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

767434:FRAAU RS01960
gene id: 767434:FRAAU_RS01960
uniprot id: H8L3T3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

767434:FRAAU RS02720
gene id: 767434:FRAAU_RS02720
uniprot id: H8L4V9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

767434:FRAAU RS11785
gene id: 767434:FRAAU_RS11785
uniprot id: H8L604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

767434:FRAAU RS13110
gene id: 767434:FRAAU_RS13110
uniprot id: H8KYW2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

767434:FRAAU RS07040
gene id: 767434:FRAAU_RS07040
uniprot id: H8L5V1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

767434:FRAAU RS08920
gene id: 767434:FRAAU_RS08920
uniprot id: H8KZG6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

767434:FRAAU RS12410
gene id: 767434:FRAAU_RS12410
uniprot id: H8L6Q0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

767434:FRAAU RS03855
gene id: 767434:FRAAU_RS03855
uniprot id: H8KZX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

767434:FRAAU RS01750
gene id: 767434:FRAAU_RS01750
uniprot id: H8L345
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

767434:FRAAU RS03680
gene id: 767434:FRAAU_RS03680
uniprot id: H8KZB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

767434:FRAAU RS00320
gene id: 767434:FRAAU_RS00320
uniprot id: H8KZQ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS04270
gene id: 767434:FRAAU_RS04270
uniprot id: H8L0T0
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

767434:FRAAU RS01575
gene id: 767434:FRAAU_RS01575
uniprot id: H8L312
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

767434:FRAAU RS12665
gene id: 767434:FRAAU_RS12665
uniprot id: H8L6Z6
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

767434:FRAAU RS05700
gene id: 767434:FRAAU_RS05700
uniprot id: H8L415
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.