760192:HALHY RS02720
gene id: 760192:HALHY_RS02720
uniprot id: F4L0E3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760192:HALHY RS29055
gene id: 760192:HALHY_RS29055
uniprot id: F4KY04
names: Similarity
messages: Belongs to the phosphohexose mutase family.

760192:HALHY RS17330
gene id: 760192:HALHY_RS17330
uniprot id: F4KVJ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

760192:HALHY RS14820
gene id: 760192:HALHY_RS14820
uniprot id: F4L5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

760192:HALHY RS06815
gene id: 760192:HALHY_RS06815
uniprot id: F4KW60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS34235
gene id: 760192:HALHY_RS34235
uniprot id: F4L8F2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS07435
gene id: 760192:HALHY_RS07435
uniprot id: F4KYD2
names: Similarity
messages: Belongs to the HsdR family.

760192:HALHY RS32440
gene id: 760192:HALHY_RS32440
uniprot id: F4KRA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

760192:HALHY RS07270
gene id: 760192:HALHY_RS07270
uniprot id: F4KXD2
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

760192:HALHY RS03790
gene id: 760192:HALHY_RS03790
uniprot id: F4L3R0
names: Similarity
messages: Belongs to the peptidase S24 family.

760192:HALHY RS33315
gene id: 760192:HALHY_RS33315
uniprot id: F4L7W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

760192:HALHY RS22925
gene id: 760192:HALHY_RS22925
uniprot id: F4KUH3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

760192:HALHY RS05620
gene id: 760192:HALHY_RS05620
uniprot id: F4KRM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

760192:HALHY RS19775
gene id: 760192:HALHY_RS19775
uniprot id: F4L4B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

760192:HALHY RS23780
gene id: 760192:HALHY_RS23780
uniprot id: F4KWU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

760192:HALHY RS16345
gene id: 760192:HALHY_RS16345
uniprot id: F4KS24
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

760192:HALHY RS03130
gene id: 760192:HALHY_RS03130
uniprot id: F4L1J3
names: Similarity
messages: Belongs to the LOG family.

760192:HALHY RS11850
gene id: 760192:HALHY_RS11850
uniprot id: F4KVA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

760192:HALHY RS28030
gene id: 760192:HALHY_RS28030
uniprot id: F4KTQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS36075
gene id: 760192:HALHY_RS36075
uniprot id: F4L197
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

760192:HALHY RS11125
gene id: 760192:HALHY_RS11125
uniprot id: F4KT24
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS16790
gene id: 760192:HALHY_RS16790
uniprot id: F4KUB9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

760192:HALHY RS30815
gene id: 760192:HALHY_RS30815
uniprot id: F4L3M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

760192:HALHY RS02670
gene id: 760192:HALHY_RS02670
uniprot id: F4KZE9
names: Similarity
messages: Belongs to the AHA1 family.

760192:HALHY RS29425
gene id: 760192:HALHY_RS29425
uniprot id: F4KZ50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

760192:HALHY RS28440
gene id: 760192:HALHY_RS28440
uniprot id: F4KVT4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS22865
gene id: 760192:HALHY_RS22865
uniprot id: F4KTI9
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS25995
gene id: 760192:HALHY_RS25995
uniprot id: F4L4R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS02120
gene id: 760192:HALHY_RS02120
uniprot id: F4KY67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

760192:HALHY RS02300
gene id: 760192:HALHY_RS02300
uniprot id: F4KYA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

760192:HALHY RS30225
gene id: 760192:HALHY_RS30225
uniprot id: F4L1G4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

760192:HALHY RS22430
gene id: 760192:HALHY_RS22430
uniprot id: F4KS71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

760192:HALHY RS02130
gene id: 760192:HALHY_RS02130
uniprot id: F4KY69
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS33135
gene id: 760192:HALHY_RS33135
uniprot id: F4L7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

760192:HALHY RS34720
gene id: 760192:HALHY_RS34720
uniprot id: F4KRQ4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

760192:HALHY RS05860
gene id: 760192:HALHY_RS05860
uniprot id: F4KSV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

760192:HALHY RS00280
gene id: 760192:HALHY_RS00280
uniprot id: F4KRI0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS07180
gene id: 760192:HALHY_RS07180
uniprot id: F4KXB3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

760192:HALHY RS32285
gene id: 760192:HALHY_RS32285
uniprot id: F4KR79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
messages: Monomer.
messages: Periplasm

760192:HALHY RS03845
gene id: 760192:HALHY_RS03845
uniprot id: F4L3S0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

760192:HALHY RS00730
gene id: 760192:HALHY_RS00730
uniprot id: F4KTR3
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

760192:HALHY RS10690
gene id: 760192:HALHY_RS10690
uniprot id: F4KRQ5
names: Similarity
messages: Belongs to the MoaD family.

760192:HALHY RS04540
gene id: 760192:HALHY_RS04540
uniprot id: F4L6C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS19020
gene id: 760192:HALHY_RS19020
uniprot id: F4L148
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

760192:HALHY RS24315
gene id: 760192:HALHY_RS24315
uniprot id: F4KYZ7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

760192:HALHY RS00900
gene id: 760192:HALHY_RS00900
uniprot id: F4KTU7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760192:HALHY RS20950
gene id: 760192:HALHY_RS20950
uniprot id: F4L5R5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

760192:HALHY RS16960
gene id: 760192:HALHY_RS16960
uniprot id: F4KUF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

760192:HALHY RS16800
gene id: 760192:HALHY_RS16800
uniprot id: F4KUC1
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS23655
gene id: 760192:HALHY_RS23655
uniprot id: F4KWS1
names: Similarity
messages: Belongs to the peptidase C69 family.

760192:HALHY RS00895
gene id: 760192:HALHY_RS00895
uniprot id: F4KTU6
names: Similarity
messages: Belongs to the universal stress protein A family.

760192:HALHY RS12880
gene id: 760192:HALHY_RS12880
uniprot id: F4KYM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

760192:HALHY RS12555
gene id: 760192:HALHY_RS12555
uniprot id: F4KXJ6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS33610
gene id: 760192:HALHY_RS33610
uniprot id: F4L831
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

760192:HALHY RS31305
gene id: 760192:HALHY_RS31305
uniprot id: F4L651
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

760192:HALHY RS26580
gene id: 760192:HALHY_RS26580
uniprot id: F4L7A5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

760192:HALHY RS35480
gene id: 760192:HALHY_RS35480
uniprot id: F4L2L2
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

760192:HALHY RS22070
gene id: 760192:HALHY_RS22070
uniprot id: F4KQW1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

760192:HALHY RS23875
gene id: 760192:HALHY_RS23875
uniprot id: F4KXT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

760192:HALHY RS24280
gene id: 760192:HALHY_RS24280
uniprot id: F4KYZ0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS14585
gene id: 760192:HALHY_RS14585
uniprot id: F4L466
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

760192:HALHY RS28520
gene id: 760192:HALHY_RS28520
uniprot id: F4KVU7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

760192:HALHY RS14340
gene id: 760192:HALHY_RS14340
uniprot id: F4L356
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

760192:HALHY RS14670
gene id: 760192:HALHY_RS14670
uniprot id: F4L483
names: Similarity
messages: Belongs to the universal stress protein A family.

760192:HALHY RS18135
gene id: 760192:HALHY_RS18135
uniprot id: F4KYR9
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

760192:HALHY RS27105
gene id: 760192:HALHY_RS27105
uniprot id: F4KQZ8
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

760192:HALHY RS32535
gene id: 760192:HALHY_RS32535
uniprot id: F4KSG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

760192:HALHY RS23785
gene id: 760192:HALHY_RS23785
uniprot id: F4KWU7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

760192:HALHY RS32630
gene id: 760192:HALHY_RS32630
uniprot id: F4KSI4
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

760192:HALHY RS27280
gene id: 760192:HALHY_RS27280
uniprot id: F4KR34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

760192:HALHY RS18780
gene id: 760192:HALHY_RS18780
uniprot id: F4L104
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS00005
gene id: 760192:HALHY_RS00005
uniprot id: F4KRC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

760192:HALHY RS30395
gene id: 760192:HALHY_RS30395
uniprot id: F4L2H7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS16105
gene id: 760192:HALHY_RS16105
uniprot id: F4KRX5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS23870
gene id: 760192:HALHY_RS23870
uniprot id: F4KXT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

760192:HALHY RS28890
gene id: 760192:HALHY_RS28890
uniprot id: F4KWZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

760192:HALHY RS06885
gene id: 760192:HALHY_RS06885
uniprot id: F4KW74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS29045
gene id: 760192:HALHY_RS29045
uniprot id: F4KY02
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS30520
gene id: 760192:HALHY_RS30520
uniprot id: F4L2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

760192:HALHY RS08920
gene id: 760192:HALHY_RS08920
uniprot id: F4L2Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

760192:HALHY RS18430
gene id: 760192:HALHY_RS18430
uniprot id: F4KZV1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

760192:HALHY RS00200
gene id: 760192:HALHY_RS00200
uniprot id: F4KRG5
names: Similarity
messages: Belongs to the peptidase M24B family.

760192:HALHY RS32405
gene id: 760192:HALHY_RS32405
uniprot id: F4KRA1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

760192:HALHY RS21960
gene id: 760192:HALHY_RS21960
uniprot id: F4KQT8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

760192:HALHY RS00315
gene id: 760192:HALHY_RS00315
uniprot id: F4KRI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS33065
gene id: 760192:HALHY_RS33065
uniprot id: F4L7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS05965
gene id: 760192:HALHY_RS05965
uniprot id: F4KSX1
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

760192:HALHY RS10000
gene id: 760192:HALHY_RS10000
uniprot id: F4KPC0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS02190
gene id: 760192:HALHY_RS02190
uniprot id: F4KY81
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS20455
gene id: 760192:HALHY_RS20455
uniprot id: F4L6W8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS02375
gene id: 760192:HALHY_RS02375
uniprot id: F4KYB7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760192:HALHY RS19870
gene id: 760192:HALHY_RS19870
uniprot id: F4L4D5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

760192:HALHY RS30795
gene id: 760192:HALHY_RS30795
uniprot id: F4L3M5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

760192:HALHY RS27860
gene id: 760192:HALHY_RS27860
uniprot id: F4KTL6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

760192:HALHY RS10040
gene id: 760192:HALHY_RS10040
uniprot id: F4KPC8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

760192:HALHY RS27025
gene id: 760192:HALHY_RS27025
uniprot id: F4KQ17
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

760192:HALHY RS11440
gene id: 760192:HALHY_RS11440
uniprot id: F4KU57
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS33410
gene id: 760192:HALHY_RS33410
uniprot id: F4L7Y8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

760192:HALHY RS08445
gene id: 760192:HALHY_RS08445
uniprot id: F4L1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

760192:HALHY RS05515
gene id: 760192:HALHY_RS05515
uniprot id: F4KRK2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

760192:HALHY RS15580
gene id: 760192:HALHY_RS15580
uniprot id: F4KPM0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS11665
gene id: 760192:HALHY_RS11665
uniprot id: F4KUA2
names: Similarity
messages: Belongs to the Skp family.

760192:HALHY RS28340
gene id: 760192:HALHY_RS28340
uniprot id: F4KUT6
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

760192:HALHY RS20750
gene id: 760192:HALHY_RS20750
uniprot id: F4L4I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

760192:HALHY RS22615
gene id: 760192:HALHY_RS22615
uniprot id: F4KTE0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

760192:HALHY RS14220
gene id: 760192:HALHY_RS14220
uniprot id: F4L335
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

760192:HALHY RS06525
gene id: 760192:HALHY_RS06525
uniprot id: F4KV23
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

760192:HALHY RS22810
gene id: 760192:HALHY_RS22810
uniprot id: F4KTH9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

760192:HALHY RS21790
gene id: 760192:HALHY_RS21790
uniprot id: F4KPU1
names: Similarity
messages: Belongs to the peptidase S8 family.

760192:HALHY RS01600
gene id: 760192:HALHY_RS01600
uniprot id: F4KW30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760192:HALHY RS19505
gene id: 760192:HALHY_RS19505
uniprot id: F4L3A1
names: Similarity
messages: Belongs to the peptidase M4 family.

760192:HALHY RS29905
gene id: 760192:HALHY_RS29905
uniprot id: F4L0C7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

760192:HALHY RS00175
gene id: 760192:HALHY_RS00175
uniprot id: F4KRF9
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

760192:HALHY RS16615
gene id: 760192:HALHY_RS16615
uniprot id: F4KTA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

760192:HALHY RS13070
gene id: 760192:HALHY_RS13070
uniprot id: F4KZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

760192:HALHY RS01660
gene id: 760192:HALHY_RS01660
uniprot id: F4KW42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

760192:HALHY RS20385
gene id: 760192:HALHY_RS20385
uniprot id: F4L6V4
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS33165
gene id: 760192:HALHY_RS33165
uniprot id: F4L7T6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS24430
gene id: 760192:HALHY_RS24430
uniprot id: F4KZ18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

760192:HALHY RS24090
gene id: 760192:HALHY_RS24090
uniprot id: F4KXY0
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS09130
gene id: 760192:HALHY_RS09130
uniprot id: F4L3Y6
names: Similarity
messages: Belongs to the HupF/HypC family.

760192:HALHY RS14290
gene id: 760192:HALHY_RS14290
uniprot id: F4L347
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

760192:HALHY RS00590
gene id: 760192:HALHY_RS00590
uniprot id: F4KSR7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

760192:HALHY RS04075
gene id: 760192:HALHY_RS04075
uniprot id: F4L3W3
names: Similarity
messages: Belongs to the peptidase S9C family.

760192:HALHY RS11495
gene id: 760192:HALHY_RS11495
uniprot id: F4KU68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

760192:HALHY RS32615
gene id: 760192:HALHY_RS32615
uniprot id: F4KSI1
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

760192:HALHY RS00820
gene id: 760192:HALHY_RS00820
uniprot id: F4KTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

760192:HALHY RS03140
gene id: 760192:HALHY_RS03140
uniprot id: F4L1J5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

760192:HALHY RS12975
gene id: 760192:HALHY_RS12975
uniprot id: F4KYP2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS22250
gene id: 760192:HALHY_RS22250
uniprot id: F4KS36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS30845
gene id: 760192:HALHY_RS30845
uniprot id: F4L3N5
names: Subcellular Location Annotation
messages: Cytoplasm

760192:HALHY RS33585
gene id: 760192:HALHY_RS33585
uniprot id: F4L826
names: Similarity
messages: Belongs to the peptidase S24 family.

760192:HALHY RS10770
gene id: 760192:HALHY_RS10770
uniprot id: F4KRS2
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

760192:HALHY RS15300
gene id: 760192:HALHY_RS15300
uniprot id: F4L6S0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

760192:HALHY RS25925
gene id: 760192:HALHY_RS25925
uniprot id: F4L4Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

760192:HALHY RS03715
gene id: 760192:HALHY_RS03715
uniprot id: F4L2T7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS13150
gene id: 760192:HALHY_RS13150
uniprot id: F4KZP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS29445
gene id: 760192:HALHY_RS29445
uniprot id: F4KZ54
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

760192:HALHY RS19910
gene id: 760192:HALHY_RS19910
uniprot id: F4L4E4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

760192:HALHY RS15740
gene id: 760192:HALHY_RS15740
uniprot id: F4KQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS03685
gene id: 760192:HALHY_RS03685
uniprot id: F4L2T1
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS10065
gene id: 760192:HALHY_RS10065
uniprot id: F4KPD3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS25145
gene id: 760192:HALHY_RS25145
uniprot id: F4L295
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS22825
gene id: 760192:HALHY_RS22825
uniprot id: F4KTI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS27340
gene id: 760192:HALHY_RS27340
uniprot id: F4KR46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

760192:HALHY RS01305
gene id: 760192:HALHY_RS01305
uniprot id: F4KUZ3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

760192:HALHY RS19160
gene id: 760192:HALHY_RS19160
uniprot id: F4L257
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

760192:HALHY RS11570
gene id: 760192:HALHY_RS11570
uniprot id: F4KU83
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS17140
gene id: 760192:HALHY_RS17140
uniprot id: F4KVF2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

760192:HALHY RS28445
gene id: 760192:HALHY_RS28445
uniprot id: F4KVT5
names: Similarity
messages: Belongs to the peptidase S9A family.

760192:HALHY RS09105
gene id: 760192:HALHY_RS09105
uniprot id: F4L3Y1
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS28225
gene id: 760192:HALHY_RS28225
uniprot id: F4KUR2
names: Similarity
messages: Belongs to the DEAD box helicase family.

760192:HALHY RS26185
gene id: 760192:HALHY_RS26185
uniprot id: F4L5Z4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS22060
gene id: 760192:HALHY_RS22060
uniprot id: F4KQV9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

760192:HALHY RS25280
gene id: 760192:HALHY_RS25280
uniprot id: F4L2B8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS03920
gene id: 760192:HALHY_RS03920
uniprot id: F4L3T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS00305
gene id: 760192:HALHY_RS00305
uniprot id: F4KRI4
names: Subcellular Location Annotation
messages: Cytoplasm

760192:HALHY RS08425
gene id: 760192:HALHY_RS08425
uniprot id: F4L1Q5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

760192:HALHY RS16380
gene id: 760192:HALHY_RS16380
uniprot id: F4KS31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

760192:HALHY RS02775
gene id: 760192:HALHY_RS02775
uniprot id: F4L0F5
names: Similarity
messages: Belongs to the peptidase M1 family.

760192:HALHY RS08705
gene id: 760192:HALHY_RS08705
uniprot id: F4L2U4
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS08710
gene id: 760192:HALHY_RS08710
uniprot id: F4L2U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS13735
gene id: 760192:HALHY_RS13735
uniprot id: F4L1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

760192:HALHY RS16600
gene id: 760192:HALHY_RS16600
uniprot id: F4KTA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

760192:HALHY RS17735
gene id: 760192:HALHY_RS17735
uniprot id: F4KXM4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS04030
gene id: 760192:HALHY_RS04030
uniprot id: F4L3V4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

760192:HALHY RS28265
gene id: 760192:HALHY_RS28265
uniprot id: F4KUS1
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

760192:HALHY RS32525
gene id: 760192:HALHY_RS32525
uniprot id: F4KSG2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS24450
gene id: 760192:HALHY_RS24450
uniprot id: F4KZ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

760192:HALHY RS04775
gene id: 760192:HALHY_RS04775
uniprot id: F4KP57
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS17975
gene id: 760192:HALHY_RS17975
uniprot id: F4KXS1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

760192:HALHY RS08500
gene id: 760192:HALHY_RS08500
uniprot id: F4L1S1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

760192:HALHY RS03795
gene id: 760192:HALHY_RS03795
uniprot id: F4L3R1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

760192:HALHY RS14900
gene id: 760192:HALHY_RS14900
uniprot id: F4L5G2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

760192:HALHY RS14565
gene id: 760192:HALHY_RS14565
uniprot id: F4L462
names: Similarity
messages: Belongs to the NodU/CmcH family.

760192:HALHY RS31140
gene id: 760192:HALHY_RS31140
uniprot id: F4L4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

760192:HALHY RS13850
gene id: 760192:HALHY_RS13850
uniprot id: F4L1Z0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS21550
gene id: 760192:HALHY_RS21550
uniprot id: F4L767
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

760192:HALHY RS16180
gene id: 760192:HALHY_RS16180
uniprot id: F4KRZ1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

760192:HALHY RS07175
gene id: 760192:HALHY_RS07175
uniprot id: F4KXB2
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

760192:HALHY RS13230
gene id: 760192:HALHY_RS13230
uniprot id: F4KZR4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS27965
gene id: 760192:HALHY_RS27965
uniprot id: F4KTN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS06480
gene id: 760192:HALHY_RS06480
uniprot id: F4KV14
names: Similarity
messages: Belongs to the histone deacetylase family.

760192:HALHY RS24445
gene id: 760192:HALHY_RS24445
uniprot id: F4KZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS13505
gene id: 760192:HALHY_RS13505
uniprot id: F4L0U9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

760192:HALHY RS30015
gene id: 760192:HALHY_RS30015
uniprot id: F4L1C5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

760192:HALHY RS21900
gene id: 760192:HALHY_RS21900
uniprot id: F4KPW2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS20115
gene id: 760192:HALHY_RS20115
uniprot id: F4L5L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

760192:HALHY RS02390
gene id: 760192:HALHY_RS02390
uniprot id: F4KYC0
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

760192:HALHY RS18695
gene id: 760192:HALHY_RS18695
uniprot id: F4L004
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS23855
gene id: 760192:HALHY_RS23855
uniprot id: F4KXT5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

760192:HALHY RS17625
gene id: 760192:HALHY_RS17625
uniprot id: F4KWM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

760192:HALHY RS01190
gene id: 760192:HALHY_RS01190
uniprot id: F4KUX2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

760192:HALHY RS13220
gene id: 760192:HALHY_RS13220
uniprot id: F4KZR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS20505
gene id: 760192:HALHY_RS20505
uniprot id: F4L6X9
names: Similarity
messages: Belongs to the AHA1 family.

760192:HALHY RS13720
gene id: 760192:HALHY_RS13720
uniprot id: F4L1W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

760192:HALHY RS10240
gene id: 760192:HALHY_RS10240
uniprot id: F4KPG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS00080
gene id: 760192:HALHY_RS00080
uniprot id: F4KRE0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS12480
gene id: 760192:HALHY_RS12480
uniprot id: F4KXI1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

760192:HALHY RS26895
gene id: 760192:HALHY_RS26895
uniprot id: F4KPZ1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

760192:HALHY RS09465
gene id: 760192:HALHY_RS09465
uniprot id: F4L589
names: Similarity
messages: Belongs to the peptidase S8 family.

760192:HALHY RS08995
gene id: 760192:HALHY_RS08995
uniprot id: F4L2Z7
names: Similarity
messages: Belongs to the acetokinase family.

760192:HALHY RS12545
gene id: 760192:HALHY_RS12545
uniprot id: F4KXJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

760192:HALHY RS31915
gene id: 760192:HALHY_RS31915
uniprot id: F4KQ30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

760192:HALHY RS16565
gene id: 760192:HALHY_RS16565
uniprot id: F4KT98
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

760192:HALHY RS29380
gene id: 760192:HALHY_RS29380
uniprot id: F4KZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS11215
gene id: 760192:HALHY_RS11215
uniprot id: F4KT41
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

760192:HALHY RS24000
gene id: 760192:HALHY_RS24000
uniprot id: F4KXW3
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

760192:HALHY RS25325
gene id: 760192:HALHY_RS25325
uniprot id: F4L2C7
names: Subcellular Location Annotation
messages: Nucleus

760192:HALHY RS21645
gene id: 760192:HALHY_RS21645
uniprot id: F4KPR1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

760192:HALHY RS29460
gene id: 760192:HALHY_RS29460
uniprot id: F4KZ57
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS27975
gene id: 760192:HALHY_RS27975
uniprot id: F4KTN9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

760192:HALHY RS13625
gene id: 760192:HALHY_RS13625
uniprot id: F4L0X3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

760192:HALHY RS28620
gene id: 760192:HALHY_RS28620
uniprot id: F4KVW8
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

760192:HALHY RS10755
gene id: 760192:HALHY_RS10755
uniprot id: F4KRR9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

760192:HALHY RS22480
gene id: 760192:HALHY_RS22480
uniprot id: F4KS80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS18570
gene id: 760192:HALHY_RS18570
uniprot id: F4KZX8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS14895
gene id: 760192:HALHY_RS14895
uniprot id: F4L5G1
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS24325
gene id: 760192:HALHY_RS24325
uniprot id: F4KYZ9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS16705
gene id: 760192:HALHY_RS16705
uniprot id: F4KTC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

760192:HALHY RS25395
gene id: 760192:HALHY_RS25395
uniprot id: F4L2E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

760192:HALHY RS17870
gene id: 760192:HALHY_RS17870
uniprot id: F4KXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

760192:HALHY RS10135
gene id: 760192:HALHY_RS10135
uniprot id: F4KPE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS22450
gene id: 760192:HALHY_RS22450
uniprot id: F4KS75
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

760192:HALHY RS19265
gene id: 760192:HALHY_RS19265
uniprot id: F4L278
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760192:HALHY RS35150
gene id: 760192:HALHY_RS35150
uniprot id: F4KS67
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS07385
gene id: 760192:HALHY_RS07385
uniprot id: F4KYC3
names: Similarity
messages: Belongs to the FGGY kinase family.

760192:HALHY RS20865
gene id: 760192:HALHY_RS20865
uniprot id: F4L4K7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

760192:HALHY RS32620
gene id: 760192:HALHY_RS32620
uniprot id: F4KSI2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

760192:HALHY RS24785
gene id: 760192:HALHY_RS24785
uniprot id: F4L067
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS16285
gene id: 760192:HALHY_RS16285
uniprot id: F4KS12
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

760192:HALHY RS14000
gene id: 760192:HALHY_RS14000
uniprot id: F4L222
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

760192:HALHY RS13335
gene id: 760192:HALHY_RS13335
uniprot id: F4KZT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

760192:HALHY RS01435
gene id: 760192:HALHY_RS01435
uniprot id: F4KVZ6
names: Similarity
messages: Belongs to the HSP15 family.

760192:HALHY RS25410
gene id: 760192:HALHY_RS25410
uniprot id: F4L2E4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS25845
gene id: 760192:HALHY_RS25845
uniprot id: F4L4N6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

760192:HALHY RS22950
gene id: 760192:HALHY_RS22950
uniprot id: F4KUH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

760192:HALHY RS23815
gene id: 760192:HALHY_RS23815
uniprot id: F4KWV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

760192:HALHY RS08805
gene id: 760192:HALHY_RS08805
uniprot id: F4L2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS07045
gene id: 760192:HALHY_RS07045
uniprot id: F4KWA7
names: Similarity
messages: Belongs to the peptidase S51 family.

760192:HALHY RS12730
gene id: 760192:HALHY_RS12730
uniprot id: F4KYJ8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS34055
gene id: 760192:HALHY_RS34055
uniprot id: F4L8B8
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS23245
gene id: 760192:HALHY_RS23245
uniprot id: F4KVL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS01605
gene id: 760192:HALHY_RS01605
uniprot id: F4KW31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760192:HALHY RS21565
gene id: 760192:HALHY_RS21565
uniprot id: F4L770
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

760192:HALHY RS29455
gene id: 760192:HALHY_RS29455
uniprot id: F4KZ56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

760192:HALHY RS21835
gene id: 760192:HALHY_RS21835
uniprot id: F4KPV0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

760192:HALHY RS17720
gene id: 760192:HALHY_RS17720
uniprot id: F4KXM1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

760192:HALHY RS32975
gene id: 760192:HALHY_RS32975
uniprot id: F4L7P4
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS12660
gene id: 760192:HALHY_RS12660
uniprot id: F4KXL8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

760192:HALHY RS28500
gene id: 760192:HALHY_RS28500
uniprot id: F4KVU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS01890
gene id: 760192:HALHY_RS01890
uniprot id: F4KX58
names: Similarity
messages: Belongs to the asparagine synthetase family.

760192:HALHY RS13895
gene id: 760192:HALHY_RS13895
uniprot id: F4L1Z8
names: Similarity
messages: Belongs to the UPF0758 family.

760192:HALHY RS18370
gene id: 760192:HALHY_RS18370
uniprot id: F4KYW7
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS16275
gene id: 760192:HALHY_RS16275
uniprot id: F4KS10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

760192:HALHY RS17995
gene id: 760192:HALHY_RS17995
uniprot id: F4KXS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

760192:HALHY RS01815
gene id: 760192:HALHY_RS01815
uniprot id: F4KX43
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

760192:HALHY RS16340
gene id: 760192:HALHY_RS16340
uniprot id: F4KS23
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

760192:HALHY RS08040
gene id: 760192:HALHY_RS08040
uniprot id: F4KZM0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

760192:HALHY RS15435
gene id: 760192:HALHY_RS15435
uniprot id: F4KPI9
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS17125
gene id: 760192:HALHY_RS17125
uniprot id: F4KVE9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

760192:HALHY RS31120
gene id: 760192:HALHY_RS31120
uniprot id: F4L4X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

760192:HALHY RS15090
gene id: 760192:HALHY_RS15090
uniprot id: F4L6N3
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS09990
gene id: 760192:HALHY_RS09990
uniprot id: F4L6M9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

760192:HALHY RS15320
gene id: 760192:HALHY_RS15320
uniprot id: F4L6S4
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

760192:HALHY RS24065
gene id: 760192:HALHY_RS24065
uniprot id: F4KXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

760192:HALHY RS00835
gene id: 760192:HALHY_RS00835
uniprot id: F4KTT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

760192:HALHY RS19425
gene id: 760192:HALHY_RS19425
uniprot id: F4L384
names: Similarity
messages: Belongs to the UPF0102 family.

760192:HALHY RS18415
gene id: 760192:HALHY_RS18415
uniprot id: F4KZU8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

760192:HALHY RS24260
gene id: 760192:HALHY_RS24260
uniprot id: F4KYY6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

760192:HALHY RS04100
gene id: 760192:HALHY_RS04100
uniprot id: F4KZC7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

760192:HALHY RS15510
gene id: 760192:HALHY_RS15510
uniprot id: F4KPK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

760192:HALHY RS03510
gene id: 760192:HALHY_RS03510
uniprot id: F4L2P6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS06420
gene id: 760192:HALHY_RS06420
uniprot id: F4KU32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

760192:HALHY RS21985
gene id: 760192:HALHY_RS21985
uniprot id: F4KQU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

760192:HALHY RS22690
gene id: 760192:HALHY_RS22690
uniprot id: F4KTF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

760192:HALHY RS28315
gene id: 760192:HALHY_RS28315
uniprot id: F4KUT1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

760192:HALHY RS28860
gene id: 760192:HALHY_RS28860
uniprot id: F4KWZ0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS11625
gene id: 760192:HALHY_RS11625
uniprot id: F4KU94
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS09505
gene id: 760192:HALHY_RS09505
uniprot id: F4L597
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

760192:HALHY RS00915
gene id: 760192:HALHY_RS00915
uniprot id: F4KTV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

760192:HALHY RS12690
gene id: 760192:HALHY_RS12690
uniprot id: F4KYI9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

760192:HALHY RS27600
gene id: 760192:HALHY_RS27600
uniprot id: F4KSD5
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS11800
gene id: 760192:HALHY_RS11800
uniprot id: F4KV97
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS10420
gene id: 760192:HALHY_RS10420
uniprot id: F4KQG7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS32035
gene id: 760192:HALHY_RS32035
uniprot id: F4KQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS27405
gene id: 760192:HALHY_RS27405
uniprot id: F4KR60
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS10355
gene id: 760192:HALHY_RS10355
uniprot id: F4KQF4
names: Similarity
messages: Belongs to the DinB family.

760192:HALHY RS09360
gene id: 760192:HALHY_RS09360
uniprot id: F4L568
names: Similarity
messages: Belongs to the SCO1/2 family.

760192:HALHY RS23795
gene id: 760192:HALHY_RS23795
uniprot id: F4KWU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

760192:HALHY RS16635
gene id: 760192:HALHY_RS16635
uniprot id: F4KTB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

760192:HALHY RS26040
gene id: 760192:HALHY_RS26040
uniprot id: F4L4S6
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

760192:HALHY RS24475
gene id: 760192:HALHY_RS24475
uniprot id: F4KZ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

760192:HALHY RS22395
gene id: 760192:HALHY_RS22395
uniprot id: F4KS63
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760192:HALHY RS27985
gene id: 760192:HALHY_RS27985
uniprot id: F4KTP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

760192:HALHY RS28625
gene id: 760192:HALHY_RS28625
uniprot id: F4KVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

760192:HALHY RS34705
gene id: 760192:HALHY_RS34705
uniprot id: F4KQH6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

760192:HALHY RS29385
gene id: 760192:HALHY_RS29385
uniprot id: F4KZ41
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS11030
gene id: 760192:HALHY_RS11030
uniprot id: F4KT06
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS23130
gene id: 760192:HALHY_RS23130
uniprot id: F4KUL3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS24165
gene id: 760192:HALHY_RS24165
uniprot id: F4KXZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

760192:HALHY RS09085
gene id: 760192:HALHY_RS09085
uniprot id: F4L3X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS16890
gene id: 760192:HALHY_RS16890
uniprot id: F4KUD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS27065
gene id: 760192:HALHY_RS27065
uniprot id: F4KQ24
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS23610
gene id: 760192:HALHY_RS23610
uniprot id: F4KWR2
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

760192:HALHY RS18805
gene id: 760192:HALHY_RS18805
uniprot id: F4L109
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS01210
gene id: 760192:HALHY_RS01210
uniprot id: F4KUX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

760192:HALHY RS28880
gene id: 760192:HALHY_RS28880
uniprot id: F4KWZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

760192:HALHY RS13155
gene id: 760192:HALHY_RS13155
uniprot id: F4KZP8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

760192:HALHY RS13945
gene id: 760192:HALHY_RS13945
uniprot id: F4L209
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS30195
gene id: 760192:HALHY_RS30195
uniprot id: F4L1F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS25550
gene id: 760192:HALHY_RS25550
uniprot id: F4L3E8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the maleate isomerase family.
messages: Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
messages: Homodimer.
messages: Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate.

760192:HALHY RS15295
gene id: 760192:HALHY_RS15295
uniprot id: F4L6R9
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS00945
gene id: 760192:HALHY_RS00945
uniprot id: F4KTV6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

760192:HALHY RS12175
gene id: 760192:HALHY_RS12175
uniprot id: F4KWE6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

760192:HALHY RS32375
gene id: 760192:HALHY_RS32375
uniprot id: F4KR95
names: Similarity
messages: Belongs to the YciI family.

760192:HALHY RS12405
gene id: 760192:HALHY_RS12405
uniprot id: F4KXG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS32185
gene id: 760192:HALHY_RS32185
uniprot id: F4KQ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

760192:HALHY RS15450
gene id: 760192:HALHY_RS15450
uniprot id: F4KPJ2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS10485
gene id: 760192:HALHY_RS10485
uniprot id: F4KQI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

760192:HALHY RS13635
gene id: 760192:HALHY_RS13635
uniprot id: F4L0X5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS34180
gene id: 760192:HALHY_RS34180
uniprot id: F4L8E0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760192:HALHY RS21195
gene id: 760192:HALHY_RS21195
uniprot id: F4L5W3
names: Similarity
messages: Belongs to the DprA/Smf family.

760192:HALHY RS11005
gene id: 760192:HALHY_RS11005
uniprot id: F4KT01
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS06210
gene id: 760192:HALHY_RS06210
uniprot id: F4KTY9
names: Subcellular Location Annotation
messages: Nucleus

760192:HALHY RS05550
gene id: 760192:HALHY_RS05550
uniprot id: F4KRK8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

760192:HALHY RS05580
gene id: 760192:HALHY_RS05580
uniprot id: F4KRL4
names: Subcellular Location Annotation
messages: Cytoplasm

760192:HALHY RS02955
gene id: 760192:HALHY_RS02955
uniprot id: F4L0J1
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

760192:HALHY RS33085
gene id: 760192:HALHY_RS33085
uniprot id: F4L7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

760192:HALHY RS24140
gene id: 760192:HALHY_RS24140
uniprot id: F4KXZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

760192:HALHY RS09135
gene id: 760192:HALHY_RS09135
uniprot id: F4L3Y7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

760192:HALHY RS06855
gene id: 760192:HALHY_RS06855
uniprot id: F4KW68
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

760192:HALHY RS15720
gene id: 760192:HALHY_RS15720
uniprot id: F4KPP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

760192:HALHY RS01405
gene id: 760192:HALHY_RS01405
uniprot id: F4KVZ0
names: Similarity
messages: Belongs to the SUI1 family.

760192:HALHY RS12870
gene id: 760192:HALHY_RS12870
uniprot id: F4KYM6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

760192:HALHY RS24760
gene id: 760192:HALHY_RS24760
uniprot id: F4L061
names: Similarity
messages: Belongs to the peptidase S33 family.

760192:HALHY RS30585
gene id: 760192:HALHY_RS30585
uniprot id: F4L2L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

760192:HALHY RS15485
gene id: 760192:HALHY_RS15485
uniprot id: F4KPJ9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

760192:HALHY RS09935
gene id: 760192:HALHY_RS09935
uniprot id: F4L6M3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

760192:HALHY RS31270
gene id: 760192:HALHY_RS31270
uniprot id: F4L644
names: Similarity
messages: Belongs to the SAICAR synthetase family.

760192:HALHY RS19110
gene id: 760192:HALHY_RS19110
uniprot id: F4L246
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

760192:HALHY RS05975
gene id: 760192:HALHY_RS05975
uniprot id: F4KSX3
names: Similarity
messages: Belongs to the glutamate synthase family.

760192:HALHY RS05840
gene id: 760192:HALHY_RS05840
uniprot id: F4KSU8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS34085
gene id: 760192:HALHY_RS34085
uniprot id: F4L8C5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

760192:HALHY RS10900
gene id: 760192:HALHY_RS10900
uniprot id: F4KRU8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS21190
gene id: 760192:HALHY_RS21190
uniprot id: F4L5W2
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

760192:HALHY RS25665
gene id: 760192:HALHY_RS25665
uniprot id: F4L3H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

760192:HALHY RS08600
gene id: 760192:HALHY_RS08600
uniprot id: F4L1U3
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

760192:HALHY RS29430
gene id: 760192:HALHY_RS29430
uniprot id: F4KZ51
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

760192:HALHY RS05640
gene id: 760192:HALHY_RS05640
uniprot id: F4KRM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS30385
gene id: 760192:HALHY_RS30385
uniprot id: F4L2H5
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

760192:HALHY RS12655
gene id: 760192:HALHY_RS12655
uniprot id: F4KXL7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

760192:HALHY RS04150
gene id: 760192:HALHY_RS04150
uniprot id: F4L513
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

760192:HALHY RS21975
gene id: 760192:HALHY_RS21975
uniprot id: F4KQU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

760192:HALHY RS14990
gene id: 760192:HALHY_RS14990
uniprot id: F4L5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

760192:HALHY RS17220
gene id: 760192:HALHY_RS17220
uniprot id: F4KVG7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS24630
gene id: 760192:HALHY_RS24630
uniprot id: F4L037
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

760192:HALHY RS14985
gene id: 760192:HALHY_RS14985
uniprot id: F4L5H9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS19615
gene id: 760192:HALHY_RS19615
uniprot id: F4L3C0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS18275
gene id: 760192:HALHY_RS18275
uniprot id: F4KYU8
names: Subcellular Location Annotation
messages: Cytoplasm

760192:HALHY RS33590
gene id: 760192:HALHY_RS33590
uniprot id: F4L827
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

760192:HALHY RS34000
gene id: 760192:HALHY_RS34000
uniprot id: F4L8A8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

760192:HALHY RS01295
gene id: 760192:HALHY_RS01295
uniprot id: F4KUZ1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

760192:HALHY RS11830
gene id: 760192:HALHY_RS11830
uniprot id: F4KVA3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS16145
gene id: 760192:HALHY_RS16145
uniprot id: F4KRY4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

760192:HALHY RS21020
gene id: 760192:HALHY_RS21020
uniprot id: F4L5S9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS11820
gene id: 760192:HALHY_RS11820
uniprot id: F4KVA1
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

760192:HALHY RS35250
gene id: 760192:HALHY_RS35250
uniprot id: F4L060
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

760192:HALHY RS19295
gene id: 760192:HALHY_RS19295
uniprot id: F4L284
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS35485
gene id: 760192:HALHY_RS35485
uniprot id: F4L2M3
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS04305
gene id: 760192:HALHY_RS04305
uniprot id: F4L543
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

760192:HALHY RS23790
gene id: 760192:HALHY_RS23790
uniprot id: F4KWU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

760192:HALHY RS35645
gene id: 760192:HALHY_RS35645
uniprot id: F4L829
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

760192:HALHY RS08100
gene id: 760192:HALHY_RS08100
uniprot id: F4L0M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

760192:HALHY RS05535
gene id: 760192:HALHY_RS05535
uniprot id: F4KRK5
names: Similarity
messages: Belongs to the peptidase S8 family.

760192:HALHY RS13660
gene id: 760192:HALHY_RS13660
uniprot id: F4L0Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

760192:HALHY RS27660
gene id: 760192:HALHY_RS27660
uniprot id: F4KSE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

760192:HALHY RS27535
gene id: 760192:HALHY_RS27535
uniprot id: F4KSC1
names: Similarity
messages: Belongs to the pirin family.

760192:HALHY RS26350
gene id: 760192:HALHY_RS26350
uniprot id: F4L626
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS14655
gene id: 760192:HALHY_RS14655
uniprot id: F4L480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

760192:HALHY RS03560
gene id: 760192:HALHY_RS03560
uniprot id: F4L2Q6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

760192:HALHY RS08245
gene id: 760192:HALHY_RS08245
uniprot id: F4L0P8
names: Similarity
messages: Belongs to the peptidase S33 family.

760192:HALHY RS25725
gene id: 760192:HALHY_RS25725
uniprot id: F4L3I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS16865
gene id: 760192:HALHY_RS16865
uniprot id: F4KUD3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS24085
gene id: 760192:HALHY_RS24085
uniprot id: F4KXX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS01525
gene id: 760192:HALHY_RS01525
uniprot id: F4KW15
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

760192:HALHY RS14925
gene id: 760192:HALHY_RS14925
uniprot id: F4L5G7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

760192:HALHY RS31520
gene id: 760192:HALHY_RS31520
uniprot id: F4L692
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS10800
gene id: 760192:HALHY_RS10800
uniprot id: F4KRS8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS09430
gene id: 760192:HALHY_RS09430
uniprot id: F4L582
names: Similarity
messages: Belongs to the TrpF family.

760192:HALHY RS22900
gene id: 760192:HALHY_RS22900
uniprot id: F4KUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

760192:HALHY RS23960
gene id: 760192:HALHY_RS23960
uniprot id: F4KXV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

760192:HALHY RS09120
gene id: 760192:HALHY_RS09120
uniprot id: F4L3Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS31845
gene id: 760192:HALHY_RS31845
uniprot id: F4L7J7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

760192:HALHY RS00860
gene id: 760192:HALHY_RS00860
uniprot id: F4KTT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

760192:HALHY RS31645
gene id: 760192:HALHY_RS31645
uniprot id: F4L7F5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

760192:HALHY RS00840
gene id: 760192:HALHY_RS00840
uniprot id: F4KTT5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS14780
gene id: 760192:HALHY_RS14780
uniprot id: F4L5D9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS18620
gene id: 760192:HALHY_RS18620
uniprot id: F4KZY9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760192:HALHY RS21445
gene id: 760192:HALHY_RS21445
uniprot id: F4L747
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

760192:HALHY RS12780
gene id: 760192:HALHY_RS12780
uniprot id: F4KYK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

760192:HALHY RS12540
gene id: 760192:HALHY_RS12540
uniprot id: F4KXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

760192:HALHY RS02790
gene id: 760192:HALHY_RS02790
uniprot id: F4L0F8
names: Similarity
messages: Belongs to the peptidase S8 family.

760192:HALHY RS26685
gene id: 760192:HALHY_RS26685
uniprot id: F4L7C7
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

760192:HALHY RS30990
gene id: 760192:HALHY_RS30990
uniprot id: F4L4U5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

760192:HALHY RS31490
gene id: 760192:HALHY_RS31490
uniprot id: F4L687
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

760192:HALHY RS10560
gene id: 760192:HALHY_RS10560
uniprot id: F4KQJ4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

760192:HALHY RS02310
gene id: 760192:HALHY_RS02310
uniprot id: F4KYA4
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

760192:HALHY RS23345
gene id: 760192:HALHY_RS23345
uniprot id: F4KVN7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

760192:HALHY RS06660
gene id: 760192:HALHY_RS06660
uniprot id: F4KV50
names: Similarity
messages: Belongs to the peptidase S9C family.

760192:HALHY RS33905
gene id: 760192:HALHY_RS33905
uniprot id: F4L889
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS35980
gene id: 760192:HALHY_RS35980
uniprot id: F4L5P2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

760192:HALHY RS12840
gene id: 760192:HALHY_RS12840
uniprot id: F4KYM0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS23805
gene id: 760192:HALHY_RS23805
uniprot id: F4KWV1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

760192:HALHY RS19240
gene id: 760192:HALHY_RS19240
uniprot id: F4L273
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

760192:HALHY RS25110
gene id: 760192:HALHY_RS25110
uniprot id: F4L1A9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS14580
gene id: 760192:HALHY_RS14580
uniprot id: F4L465
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS26640
gene id: 760192:HALHY_RS26640
uniprot id: F4L7B8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

760192:HALHY RS29770
gene id: 760192:HALHY_RS29770
uniprot id: F4L0A1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS26965
gene id: 760192:HALHY_RS26965
uniprot id: F4KQ05
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS25300
gene id: 760192:HALHY_RS25300
uniprot id: F4L2C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

760192:HALHY RS11910
gene id: 760192:HALHY_RS11910
uniprot id: F4KVC0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS16560
gene id: 760192:HALHY_RS16560
uniprot id: F4KT97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS29415
gene id: 760192:HALHY_RS29415
uniprot id: F4KZ48
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

760192:HALHY RS27140
gene id: 760192:HALHY_RS27140
uniprot id: F4KR06
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

760192:HALHY RS32485
gene id: 760192:HALHY_RS32485
uniprot id: F4KRB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

760192:HALHY RS04385
gene id: 760192:HALHY_RS04385
uniprot id: F4L556
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS05560
gene id: 760192:HALHY_RS05560
uniprot id: F4KRL0
names: Similarity
messages: Belongs to the YciI family.

760192:HALHY RS08750
gene id: 760192:HALHY_RS08750
uniprot id: F4L2V2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

760192:HALHY RS13965
gene id: 760192:HALHY_RS13965
uniprot id: F4L213
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS27760
gene id: 760192:HALHY_RS27760
uniprot id: F4KTJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

760192:HALHY RS16270
gene id: 760192:HALHY_RS16270
uniprot id: F4KS09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

760192:HALHY RS30305
gene id: 760192:HALHY_RS30305
uniprot id: F4L2F9
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS03180
gene id: 760192:HALHY_RS03180
uniprot id: F4L1K4
names: Similarity
messages: Belongs to the ArsC family.

760192:HALHY RS09560
gene id: 760192:HALHY_RS09560
uniprot id: F4L5A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

760192:HALHY RS00230
gene id: 760192:HALHY_RS00230
uniprot id: F4KRH0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS25010
gene id: 760192:HALHY_RS25010
uniprot id: F4L189
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS13195
gene id: 760192:HALHY_RS13195
uniprot id: F4KZQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

760192:HALHY RS15695
gene id: 760192:HALHY_RS15695
uniprot id: F4KPP3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

760192:HALHY RS12765
gene id: 760192:HALHY_RS12765
uniprot id: F4KYK5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

760192:HALHY RS29505
gene id: 760192:HALHY_RS29505
uniprot id: F4KZ65
names: Similarity
messages: Belongs to the peptidase S8 family.

760192:HALHY RS06535
gene id: 760192:HALHY_RS06535
uniprot id: F4KV25
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

760192:HALHY RS33510
gene id: 760192:HALHY_RS33510
uniprot id: F4L808
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS08585
gene id: 760192:HALHY_RS08585
uniprot id: F4L1U0
names: Similarity
messages: Belongs to the peptidase S41A family.

760192:HALHY RS28025
gene id: 760192:HALHY_RS28025
uniprot id: F4KTP9
names: Subcellular Location Annotation
messages: Cytoplasm

760192:HALHY RS33070
gene id: 760192:HALHY_RS33070
uniprot id: F4L7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS03905
gene id: 760192:HALHY_RS03905
uniprot id: F4L3T0
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

760192:HALHY RS17090
gene id: 760192:HALHY_RS17090
uniprot id: F4KVE2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760192:HALHY RS33340
gene id: 760192:HALHY_RS33340
uniprot id: F4L7X1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

760192:HALHY RS00050
gene id: 760192:HALHY_RS00050
uniprot id: F4KRD4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

760192:HALHY RS18000
gene id: 760192:HALHY_RS18000
uniprot id: F4KXS6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

760192:HALHY RS10080
gene id: 760192:HALHY_RS10080
uniprot id: F4KPD6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

760192:HALHY RS06980
gene id: 760192:HALHY_RS06980
uniprot id: F4KW94
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

760192:HALHY RS24990
gene id: 760192:HALHY_RS24990
uniprot id: F4L185
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

760192:HALHY RS28540
gene id: 760192:HALHY_RS28540
uniprot id: F4KVV1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

760192:HALHY RS16965
gene id: 760192:HALHY_RS16965
uniprot id: F4KUF3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

760192:HALHY RS27450
gene id: 760192:HALHY_RS27450
uniprot id: F4KSA4
names: Subcellular Location Annotation
messages: Cytoplasm

760192:HALHY RS12530
gene id: 760192:HALHY_RS12530
uniprot id: F4KXJ1
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

760192:HALHY RS03750
gene id: 760192:HALHY_RS03750
uniprot id: F4L3Q3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

760192:HALHY RS19390
gene id: 760192:HALHY_RS19390
uniprot id: F4L376
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS29005
gene id: 760192:HALHY_RS29005
uniprot id: F4KX19
names: Similarity
messages: Belongs to the AlaDH/PNT family.

760192:HALHY RS26440
gene id: 760192:HALHY_RS26440
uniprot id: F4L779
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

760192:HALHY RS07610
gene id: 760192:HALHY_RS07610
uniprot id: F4KYG5
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS24170
gene id: 760192:HALHY_RS24170
uniprot id: F4KXZ6
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS13295
gene id: 760192:HALHY_RS13295
uniprot id: F4KZS7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

760192:HALHY RS16070
gene id: 760192:HALHY_RS16070
uniprot id: F4KRW8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS23945
gene id: 760192:HALHY_RS23945
uniprot id: F4KXV2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

760192:HALHY RS28125
gene id: 760192:HALHY_RS28125
uniprot id: F4KUP1
names: Similarity
messages: Belongs to the YciI family.

760192:HALHY RS00455
gene id: 760192:HALHY_RS00455
uniprot id: F4KSP0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

760192:HALHY RS13060
gene id: 760192:HALHY_RS13060
uniprot id: F4KZM8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

760192:HALHY RS02295
gene id: 760192:HALHY_RS02295
uniprot id: F4KYA1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS29865
gene id: 760192:HALHY_RS29865
uniprot id: F4L0C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

760192:HALHY RS04215
gene id: 760192:HALHY_RS04215
uniprot id: F4L524
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Membrane

760192:HALHY RS16730
gene id: 760192:HALHY_RS16730
uniprot id: F4KUA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

760192:HALHY RS00500
gene id: 760192:HALHY_RS00500
uniprot id: F4KSP9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

760192:HALHY RS08015
gene id: 760192:HALHY_RS08015
uniprot id: F4KZL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

760192:HALHY RS00565
gene id: 760192:HALHY_RS00565
uniprot id: F4KSR2
names: Similarity
messages: Belongs to the DSD1 family.

760192:HALHY RS16685
gene id: 760192:HALHY_RS16685
uniprot id: F4KTC2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

760192:HALHY RS33190
gene id: 760192:HALHY_RS33190
uniprot id: F4L7U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

760192:HALHY RS09475
gene id: 760192:HALHY_RS09475
uniprot id: F4L591
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

760192:HALHY RS04070
gene id: 760192:HALHY_RS04070
uniprot id: F4L3W2
names: Similarity
messages: Belongs to the UPF0173 family.

760192:HALHY RS25060
gene id: 760192:HALHY_RS25060
uniprot id: F4L199
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

760192:HALHY RS11525
gene id: 760192:HALHY_RS11525
uniprot id: F4KU74
names: Similarity
messages: Belongs to the peptidase M1 family.

760192:HALHY RS18955
gene id: 760192:HALHY_RS18955
uniprot id: F4L135
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

760192:HALHY RS11485
gene id: 760192:HALHY_RS11485
uniprot id: F4KU66
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS31475
gene id: 760192:HALHY_RS31475
uniprot id: F4L684
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

760192:HALHY RS23200
gene id: 760192:HALHY_RS23200
uniprot id: F4KVK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS05830
gene id: 760192:HALHY_RS05830
uniprot id: F4KSU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

760192:HALHY RS27785
gene id: 760192:HALHY_RS27785
uniprot id: F4KTK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

760192:HALHY RS25320
gene id: 760192:HALHY_RS25320
uniprot id: F4L2C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

760192:HALHY RS01820
gene id: 760192:HALHY_RS01820
uniprot id: F4KX44
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

760192:HALHY RS12270
gene id: 760192:HALHY_RS12270
uniprot id: F4KWG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

760192:HALHY RS30775
gene id: 760192:HALHY_RS30775
uniprot id: F4L3M1
names: Similarity
messages: Belongs to the aspartokinase family.

760192:HALHY RS10055
gene id: 760192:HALHY_RS10055
uniprot id: F4KPD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

760192:HALHY RS25520
gene id: 760192:HALHY_RS25520
uniprot id: F4L3E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

760192:HALHY RS01960
gene id: 760192:HALHY_RS01960
uniprot id: F4KX71
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS23760
gene id: 760192:HALHY_RS23760
uniprot id: F4KWU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

760192:HALHY RS14080
gene id: 760192:HALHY_RS14080
uniprot id: F4L312
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

760192:HALHY RS01025
gene id: 760192:HALHY_RS01025
uniprot id: F4KTX1
names: Similarity
messages: Belongs to the peptidase M16 family.

760192:HALHY RS23375
gene id: 760192:HALHY_RS23375
uniprot id: F4KVP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS01640
gene id: 760192:HALHY_RS01640
uniprot id: F4KW38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760192:HALHY RS04915
gene id: 760192:HALHY_RS04915
uniprot id: F4KP83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS13765
gene id: 760192:HALHY_RS13765
uniprot id: F4L1X2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

760192:HALHY RS23240
gene id: 760192:HALHY_RS23240
uniprot id: F4KVL5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

760192:HALHY RS18080
gene id: 760192:HALHY_RS18080
uniprot id: F4KYQ8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS07845
gene id: 760192:HALHY_RS07845
uniprot id: F4KZI1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS34995
gene id: 760192:HALHY_RS34995
uniprot id: F4KZZ7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

760192:HALHY RS08010
gene id: 760192:HALHY_RS08010
uniprot id: F4KZL4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS30355
gene id: 760192:HALHY_RS30355
uniprot id: F4L2G9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

760192:HALHY RS20395
gene id: 760192:HALHY_RS20395
uniprot id: F4L6V6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS11560
gene id: 760192:HALHY_RS11560
uniprot id: F4KU81
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

760192:HALHY RS27295
gene id: 760192:HALHY_RS27295
uniprot id: F4KR37
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

760192:HALHY RS19300
gene id: 760192:HALHY_RS19300
uniprot id: F4L285
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS32450
gene id: 760192:HALHY_RS32450
uniprot id: F4KRB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

760192:HALHY RS18390
gene id: 760192:HALHY_RS18390
uniprot id: F4KZU3
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS13805
gene id: 760192:HALHY_RS13805
uniprot id: F4L1Y1
names: Similarity
messages: Belongs to the DtxR/MntR family.

760192:HALHY RS17375
gene id: 760192:HALHY_RS17375
uniprot id: F4KVK0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

760192:HALHY RS19635
gene id: 760192:HALHY_RS19635
uniprot id: F4L3C4
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS10125
gene id: 760192:HALHY_RS10125
uniprot id: F4KPE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

760192:HALHY RS27655
gene id: 760192:HALHY_RS27655
uniprot id: F4KSE6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS24510
gene id: 760192:HALHY_RS24510
uniprot id: F4L011
names: Similarity
messages: Belongs to the HsdR family.

760192:HALHY RS20570
gene id: 760192:HALHY_RS20570
uniprot id: F4L6Z3
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS16720
gene id: 760192:HALHY_RS16720
uniprot id: F4KUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

760192:HALHY RS10275
gene id: 760192:HALHY_RS10275
uniprot id: F4KPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

760192:HALHY RS32505
gene id: 760192:HALHY_RS32505
uniprot id: F4KRC2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

760192:HALHY RS21025
gene id: 760192:HALHY_RS21025
uniprot id: F4L5T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

760192:HALHY RS17905
gene id: 760192:HALHY_RS17905
uniprot id: F4KXQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

760192:HALHY RS27790
gene id: 760192:HALHY_RS27790
uniprot id: F4KTK2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

760192:HALHY RS23365
gene id: 760192:HALHY_RS23365
uniprot id: F4KVP1
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS10445
gene id: 760192:HALHY_RS10445
uniprot id: F4KQH2
names: Similarity
messages: Belongs to the peptidase M16 family.

760192:HALHY RS18360
gene id: 760192:HALHY_RS18360
uniprot id: F4KYW5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS26235
gene id: 760192:HALHY_RS26235
uniprot id: F4L604
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

760192:HALHY RS29375
gene id: 760192:HALHY_RS29375
uniprot id: F4KZ39
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS06790
gene id: 760192:HALHY_RS06790
uniprot id: F4KW55
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

760192:HALHY RS16795
gene id: 760192:HALHY_RS16795
uniprot id: F4KUC0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS24440
gene id: 760192:HALHY_RS24440
uniprot id: F4KZ20
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

760192:HALHY RS13935
gene id: 760192:HALHY_RS13935
uniprot id: F4L207
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

760192:HALHY RS14115
gene id: 760192:HALHY_RS14115
uniprot id: F4L317
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS25000
gene id: 760192:HALHY_RS25000
uniprot id: F4L187
names: Similarity
messages: Belongs to the TrpF family.

760192:HALHY RS24995
gene id: 760192:HALHY_RS24995
uniprot id: F4L186
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

760192:HALHY RS12195
gene id: 760192:HALHY_RS12195
uniprot id: F4KWF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

760192:HALHY RS15705
gene id: 760192:HALHY_RS15705
uniprot id: F4KPP5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS04945
gene id: 760192:HALHY_RS04945
uniprot id: F4KP89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

760192:HALHY RS00990
gene id: 760192:HALHY_RS00990
uniprot id: F4KTW5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

760192:HALHY RS18145
gene id: 760192:HALHY_RS18145
uniprot id: F4KYS1
names: Similarity
messages: Belongs to the CarB family.

760192:HALHY RS18175
gene id: 760192:HALHY_RS18175
uniprot id: F4KYS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

760192:HALHY RS04165
gene id: 760192:HALHY_RS04165
uniprot id: F4L515
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

760192:HALHY RS11620
gene id: 760192:HALHY_RS11620
uniprot id: F4KU92
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS31610
gene id: 760192:HALHY_RS31610
uniprot id: F4L7E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS20885
gene id: 760192:HALHY_RS20885
uniprot id: F4L4L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

760192:HALHY RS18110
gene id: 760192:HALHY_RS18110
uniprot id: F4KYR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

760192:HALHY RS05470
gene id: 760192:HALHY_RS05470
uniprot id: F4KRJ4
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

760192:HALHY RS04435
gene id: 760192:HALHY_RS04435
uniprot id: F4L6A6
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

760192:HALHY RS06860
gene id: 760192:HALHY_RS06860
uniprot id: F4KW69
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

760192:HALHY RS33965
gene id: 760192:HALHY_RS33965
uniprot id: F4L8A1
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS00340
gene id: 760192:HALHY_RS00340
uniprot id: F4KSL7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

760192:HALHY RS17590
gene id: 760192:HALHY_RS17590
uniprot id: F4KWL5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS17570
gene id: 760192:HALHY_RS17570
uniprot id: F4KWL1
names: Similarity
messages: Belongs to the pirin family.

760192:HALHY RS01735
gene id: 760192:HALHY_RS01735
uniprot id: F4KX27
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS06205
gene id: 760192:HALHY_RS06205
uniprot id: F4KTY8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS17320
gene id: 760192:HALHY_RS17320
uniprot id: F4KVI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

760192:HALHY RS11980
gene id: 760192:HALHY_RS11980
uniprot id: F4KVD3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

760192:HALHY RS00015
gene id: 760192:HALHY_RS00015
uniprot id: F4KRC7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS21470
gene id: 760192:HALHY_RS21470
uniprot id: F4L752
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS28820
gene id: 760192:HALHY_RS28820
uniprot id: F4KWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

760192:HALHY RS10425
gene id: 760192:HALHY_RS10425
uniprot id: F4KQG8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS31650
gene id: 760192:HALHY_RS31650
uniprot id: F4L7F6
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

760192:HALHY RS22770
gene id: 760192:HALHY_RS22770
uniprot id: F4KTH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

760192:HALHY RS30655
gene id: 760192:HALHY_RS30655
uniprot id: F4L3J8
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

760192:HALHY RS24905
gene id: 760192:HALHY_RS24905
uniprot id: F4L168
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS17970
gene id: 760192:HALHY_RS17970
uniprot id: F4KXS0
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS22315
gene id: 760192:HALHY_RS22315
uniprot id: F4KS47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS01670
gene id: 760192:HALHY_RS01670
uniprot id: F4KW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

760192:HALHY RS21465
gene id: 760192:HALHY_RS21465
uniprot id: F4L751
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

760192:HALHY RS30810
gene id: 760192:HALHY_RS30810
uniprot id: F4L3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

760192:HALHY RS12750
gene id: 760192:HALHY_RS12750
uniprot id: F4KYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

760192:HALHY RS16910
gene id: 760192:HALHY_RS16910
uniprot id: F4KUE2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

760192:HALHY RS23660
gene id: 760192:HALHY_RS23660
uniprot id: F4KWS2
names: Similarity
messages: Belongs to the peptidase S8 family.

760192:HALHY RS30240
gene id: 760192:HALHY_RS30240
uniprot id: F4L1G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

760192:HALHY RS18295
gene id: 760192:HALHY_RS18295
uniprot id: F4KYV2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

760192:HALHY RS22440
gene id: 760192:HALHY_RS22440
uniprot id: F4KS73
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

760192:HALHY RS13725
gene id: 760192:HALHY_RS13725
uniprot id: F4L1W4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

760192:HALHY RS28990
gene id: 760192:HALHY_RS28990
uniprot id: F4KX16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS30245
gene id: 760192:HALHY_RS30245
uniprot id: F4L1G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

760192:HALHY RS23755
gene id: 760192:HALHY_RS23755
uniprot id: F4KWU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

760192:HALHY RS16465
gene id: 760192:HALHY_RS16465
uniprot id: F4KT78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

760192:HALHY RS00735
gene id: 760192:HALHY_RS00735
uniprot id: F4KTR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

760192:HALHY RS04975
gene id: 760192:HALHY_RS04975
uniprot id: F4KP95
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

760192:HALHY RS01655
gene id: 760192:HALHY_RS01655
uniprot id: F4KW41
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS35220
gene id: 760192:HALHY_RS35220
uniprot id: F4KXY7
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

760192:HALHY RS01970
gene id: 760192:HALHY_RS01970
uniprot id: F4KX73
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS27245
gene id: 760192:HALHY_RS27245
uniprot id: F4KR27
names: Similarity
messages: Belongs to the asparagine synthetase family.

760192:HALHY RS26090
gene id: 760192:HALHY_RS26090
uniprot id: F4L4T5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

760192:HALHY RS11855
gene id: 760192:HALHY_RS11855
uniprot id: F4KVA8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

760192:HALHY RS03240
gene id: 760192:HALHY_RS03240
uniprot id: F4L1L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

760192:HALHY RS33950
gene id: 760192:HALHY_RS33950
uniprot id: F4L898
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS12350
gene id: 760192:HALHY_RS12350
uniprot id: F4KXF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

760192:HALHY RS32655
gene id: 760192:HALHY_RS32655
uniprot id: F4KSI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

760192:HALHY RS31905
gene id: 760192:HALHY_RS31905
uniprot id: F4KQ28
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

760192:HALHY RS04630
gene id: 760192:HALHY_RS04630
uniprot id: F4L6E0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

760192:HALHY RS15075
gene id: 760192:HALHY_RS15075
uniprot id: F4L5J7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS06765
gene id: 760192:HALHY_RS06765
uniprot id: F4KV72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

760192:HALHY RS10005
gene id: 760192:HALHY_RS10005
uniprot id: F4KPC1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

760192:HALHY RS17645
gene id: 760192:HALHY_RS17645
uniprot id: F4KWM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

760192:HALHY RS10715
gene id: 760192:HALHY_RS10715
uniprot id: F4KRR0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS21810
gene id: 760192:HALHY_RS21810
uniprot id: F4KPU5
names: Similarity
messages: Belongs to the HypD family.

760192:HALHY RS29185
gene id: 760192:HALHY_RS29185
uniprot id: F4KY30
names: Similarity
messages: Belongs to the heat shock protein 70 family.

760192:HALHY RS16580
gene id: 760192:HALHY_RS16580
uniprot id: F4KTA1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

760192:HALHY RS09685
gene id: 760192:HALHY_RS09685
uniprot id: F4L6H3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS00355
gene id: 760192:HALHY_RS00355
uniprot id: F4KSM1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

760192:HALHY RS05205
gene id: 760192:HALHY_RS05205
uniprot id: F4KQA6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS08760
gene id: 760192:HALHY_RS08760
uniprot id: F4L2V4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS12735
gene id: 760192:HALHY_RS12735
uniprot id: F4KYJ9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

760192:HALHY RS32710
gene id: 760192:HALHY_RS32710
uniprot id: F4KSK0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS23745
gene id: 760192:HALHY_RS23745
uniprot id: F4KWT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

760192:HALHY RS09420
gene id: 760192:HALHY_RS09420
uniprot id: F4L580
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

760192:HALHY RS28235
gene id: 760192:HALHY_RS28235
uniprot id: F4KUR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

760192:HALHY RS29805
gene id: 760192:HALHY_RS29805
uniprot id: F4L0A8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

760192:HALHY RS14260
gene id: 760192:HALHY_RS14260
uniprot id: F4L342
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760192:HALHY RS01620
gene id: 760192:HALHY_RS01620
uniprot id: F4KW34
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

760192:HALHY RS14650
gene id: 760192:HALHY_RS14650
uniprot id: F4L479
names: Similarity
messages: Belongs to the peptidase M24B family.

760192:HALHY RS23770
gene id: 760192:HALHY_RS23770
uniprot id: F4KWU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

760192:HALHY RS01005
gene id: 760192:HALHY_RS01005
uniprot id: F4KTW8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS24155
gene id: 760192:HALHY_RS24155
uniprot id: F4KXZ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS13365
gene id: 760192:HALHY_RS13365
uniprot id: F4L0S3
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

760192:HALHY RS01615
gene id: 760192:HALHY_RS01615
uniprot id: F4KW33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760192:HALHY RS19380
gene id: 760192:HALHY_RS19380
uniprot id: F4L374
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS13835
gene id: 760192:HALHY_RS13835
uniprot id: F4L1Y7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS31310
gene id: 760192:HALHY_RS31310
uniprot id: F4L652
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

760192:HALHY RS32590
gene id: 760192:HALHY_RS32590
uniprot id: F4KSH6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS17640
gene id: 760192:HALHY_RS17640
uniprot id: F4KWM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS20725
gene id: 760192:HALHY_RS20725
uniprot id: F4L4H9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

760192:HALHY RS29475
gene id: 760192:HALHY_RS29475
uniprot id: F4KZ60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

760192:HALHY RS30260
gene id: 760192:HALHY_RS30260
uniprot id: F4L1H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS31745
gene id: 760192:HALHY_RS31745
uniprot id: F4L7H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

760192:HALHY RS13975
gene id: 760192:HALHY_RS13975
uniprot id: F4L215
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

760192:HALHY RS21950
gene id: 760192:HALHY_RS21950
uniprot id: F4KQT6
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS34160
gene id: 760192:HALHY_RS34160
uniprot id: F4L8D6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760192:HALHY RS28680
gene id: 760192:HALHY_RS28680
uniprot id: F4KVX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

760192:HALHY RS31685
gene id: 760192:HALHY_RS31685
uniprot id: F4L7G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS25315
gene id: 760192:HALHY_RS25315
uniprot id: F4L2C5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS11130
gene id: 760192:HALHY_RS11130
uniprot id: F4KT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

760192:HALHY RS31450
gene id: 760192:HALHY_RS31450
uniprot id: F4L679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

760192:HALHY RS08035
gene id: 760192:HALHY_RS08035
uniprot id: F4KZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

760192:HALHY RS06485
gene id: 760192:HALHY_RS06485
uniprot id: F4KV15
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS07860
gene id: 760192:HALHY_RS07860
uniprot id: F4KZI4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS17990
gene id: 760192:HALHY_RS17990
uniprot id: F4KXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

760192:HALHY RS22800
gene id: 760192:HALHY_RS22800
uniprot id: F4KTH7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS14105
gene id: 760192:HALHY_RS14105
uniprot id: F4L315
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

760192:HALHY RS19885
gene id: 760192:HALHY_RS19885
uniprot id: F4L4D9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

760192:HALHY RS26660
gene id: 760192:HALHY_RS26660
uniprot id: F4L7C2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS09005
gene id: 760192:HALHY_RS09005
uniprot id: F4L2Z9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760192:HALHY RS10345
gene id: 760192:HALHY_RS10345
uniprot id: F4KQF2
names: Similarity
messages: Belongs to the peptidase M1 family.

760192:HALHY RS20515
gene id: 760192:HALHY_RS20515
uniprot id: F4L6Y1
names: Similarity
messages: Belongs to the AHA1 family.

760192:HALHY RS13740
gene id: 760192:HALHY_RS13740
uniprot id: F4L1W7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS15650
gene id: 760192:HALHY_RS15650
uniprot id: F4KPN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

760192:HALHY RS26615
gene id: 760192:HALHY_RS26615
uniprot id: F4L7B3
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

760192:HALHY RS31740
gene id: 760192:HALHY_RS31740
uniprot id: F4L7H5
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

760192:HALHY RS18965
gene id: 760192:HALHY_RS18965
uniprot id: F4L137
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

760192:HALHY RS17495
gene id: 760192:HALHY_RS17495
uniprot id: F4KWJ6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS16550
gene id: 760192:HALHY_RS16550
uniprot id: F4KT95
names: Similarity
messages: Belongs to the DapA family.

760192:HALHY RS01855
gene id: 760192:HALHY_RS01855
uniprot id: F4KX51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

760192:HALHY RS10745
gene id: 760192:HALHY_RS10745
uniprot id: F4KRR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

760192:HALHY RS16460
gene id: 760192:HALHY_RS16460
uniprot id: F4KT77
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

760192:HALHY RS32900
gene id: 760192:HALHY_RS32900
uniprot id: F4L7M8
names: Similarity
messages: Belongs to the peptidase S24 family.

760192:HALHY RS31835
gene id: 760192:HALHY_RS31835
uniprot id: F4L7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS17810
gene id: 760192:HALHY_RS17810
uniprot id: F4KXN9
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS10985
gene id: 760192:HALHY_RS10985
uniprot id: F4KRW3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

760192:HALHY RS30170
gene id: 760192:HALHY_RS30170
uniprot id: F4L1F4
names: Similarity
messages: Belongs to the peptidase S8 family.

760192:HALHY RS20770
gene id: 760192:HALHY_RS20770
uniprot id: F4L4I8
names: Similarity
messages: Belongs to the MQO family.

760192:HALHY RS12615
gene id: 760192:HALHY_RS12615
uniprot id: F4KXK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

760192:HALHY RS03605
gene id: 760192:HALHY_RS03605
uniprot id: F4L2R5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS05820
gene id: 760192:HALHY_RS05820
uniprot id: F4KSU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS32045
gene id: 760192:HALHY_RS32045
uniprot id: F4KQ57
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

760192:HALHY RS24230
gene id: 760192:HALHY_RS24230
uniprot id: F4KYY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

760192:HALHY RS06760
gene id: 760192:HALHY_RS06760
uniprot id: F4KV71
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

760192:HALHY RS00135
gene id: 760192:HALHY_RS00135
uniprot id: F4KRF0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS18785
gene id: 760192:HALHY_RS18785
uniprot id: F4L105
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS35295
gene id: 760192:HALHY_RS35295
uniprot id: F4L3F9
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS21655
gene id: 760192:HALHY_RS21655
uniprot id: F4KPR3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

760192:HALHY RS01090
gene id: 760192:HALHY_RS01090
uniprot id: F4KUV3
names: Similarity
messages: Belongs to the aldose epimerase family.

760192:HALHY RS19485
gene id: 760192:HALHY_RS19485
uniprot id: F4L398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS20980
gene id: 760192:HALHY_RS20980
uniprot id: F4L5S1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

760192:HALHY RS22105
gene id: 760192:HALHY_RS22105
uniprot id: F4KQW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

760192:HALHY RS21945
gene id: 760192:HALHY_RS21945
uniprot id: F4KQT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS16895
gene id: 760192:HALHY_RS16895
uniprot id: F4KUD9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS26000
gene id: 760192:HALHY_RS26000
uniprot id: F4L4R8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS22930
gene id: 760192:HALHY_RS22930
uniprot id: F4KUH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

760192:HALHY RS22830
gene id: 760192:HALHY_RS22830
uniprot id: F4KTI3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS17160
gene id: 760192:HALHY_RS17160
uniprot id: F4KVF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

760192:HALHY RS27720
gene id: 760192:HALHY_RS27720
uniprot id: F4KSG0
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

760192:HALHY RS15925
gene id: 760192:HALHY_RS15925
uniprot id: F4KQQ3
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS20710
gene id: 760192:HALHY_RS20710
uniprot id: F4L4H6
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

760192:HALHY RS01625
gene id: 760192:HALHY_RS01625
uniprot id: F4KW35
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

760192:HALHY RS26680
gene id: 760192:HALHY_RS26680
uniprot id: F4L7C6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

760192:HALHY RS29115
gene id: 760192:HALHY_RS29115
uniprot id: F4KY16
names: Similarity
messages: Belongs to the pyruvate kinase family.

760192:HALHY RS22445
gene id: 760192:HALHY_RS22445
uniprot id: F4KS74
names: Similarity
messages: Belongs to the RutC family.

760192:HALHY RS05250
gene id: 760192:HALHY_RS05250
uniprot id: F4KQB5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

760192:HALHY RS17400
gene id: 760192:HALHY_RS17400
uniprot id: F4KWH8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS14620
gene id: 760192:HALHY_RS14620
uniprot id: F4L473
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

760192:HALHY RS32445
gene id: 760192:HALHY_RS32445
uniprot id: F4KRA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

760192:HALHY RS20135
gene id: 760192:HALHY_RS20135
uniprot id: F4L5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

760192:HALHY RS01665
gene id: 760192:HALHY_RS01665
uniprot id: F4KW43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760192:HALHY RS15495
gene id: 760192:HALHY_RS15495
uniprot id: F4KPK1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

760192:HALHY RS28595
gene id: 760192:HALHY_RS28595
uniprot id: F4KVW2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS04740
gene id: 760192:HALHY_RS04740
uniprot id: F4L6G2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

760192:HALHY RS05835
gene id: 760192:HALHY_RS05835
uniprot id: F4KSU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

760192:HALHY RS23765
gene id: 760192:HALHY_RS23765
uniprot id: F4KWU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

760192:HALHY RS08740
gene id: 760192:HALHY_RS08740
uniprot id: F4L2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS01795
gene id: 760192:HALHY_RS01795
uniprot id: F4KX39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

760192:HALHY RS00415
gene id: 760192:HALHY_RS00415
uniprot id: F4KSN2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

760192:HALHY RS26915
gene id: 760192:HALHY_RS26915
uniprot id: F4KPZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

760192:HALHY RS17190
gene id: 760192:HALHY_RS17190
uniprot id: F4KVG1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

760192:HALHY RS30890
gene id: 760192:HALHY_RS30890
uniprot id: F4L3P4
names: Similarity
messages: Belongs to the AAA ATPase family.

760192:HALHY RS09155
gene id: 760192:HALHY_RS09155
uniprot id: F4L3Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

760192:HALHY RS09250
gene id: 760192:HALHY_RS09250
uniprot id: F4L410
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS06805
gene id: 760192:HALHY_RS06805
uniprot id: F4KW58
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

760192:HALHY RS18720
gene id: 760192:HALHY_RS18720
uniprot id: F4L0Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

760192:HALHY RS14275
gene id: 760192:HALHY_RS14275
uniprot id: F4L345
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

760192:HALHY RS06235
gene id: 760192:HALHY_RS06235
uniprot id: F4KTZ4
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

760192:HALHY RS13110
gene id: 760192:HALHY_RS13110
uniprot id: F4KZN9
names: Similarity
messages: Belongs to the universal stress protein A family.

760192:HALHY RS19470
gene id: 760192:HALHY_RS19470
uniprot id: F4L394
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

760192:HALHY RS23955
gene id: 760192:HALHY_RS23955
uniprot id: F4KXV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

760192:HALHY RS28080
gene id: 760192:HALHY_RS28080
uniprot id: F4KUN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS09055
gene id: 760192:HALHY_RS09055
uniprot id: F4L3X2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS25140
gene id: 760192:HALHY_RS25140
uniprot id: F4L1B5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

760192:HALHY RS16005
gene id: 760192:HALHY_RS16005
uniprot id: F4KQR9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

760192:HALHY RS19270
gene id: 760192:HALHY_RS19270
uniprot id: F4L279
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

760192:HALHY RS20400
gene id: 760192:HALHY_RS20400
uniprot id: F4L6V7
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS03170
gene id: 760192:HALHY_RS03170
uniprot id: F4L1K2
names: Similarity
messages: Belongs to the AHA1 family.

760192:HALHY RS01780
gene id: 760192:HALHY_RS01780
uniprot id: F4KX36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS27645
gene id: 760192:HALHY_RS27645
uniprot id: F4KSE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

760192:HALHY RS10050
gene id: 760192:HALHY_RS10050
uniprot id: F4KPD0
names: Similarity
messages: Belongs to the citrate synthase family.

760192:HALHY RS24580
gene id: 760192:HALHY_RS24580
uniprot id: F4L024
names: Similarity
messages: Belongs to the pirin family.

760192:HALHY RS17585
gene id: 760192:HALHY_RS17585
uniprot id: F4KWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

760192:HALHY RS28570
gene id: 760192:HALHY_RS28570
uniprot id: F4KVV7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

760192:HALHY RS29890
gene id: 760192:HALHY_RS29890
uniprot id: F4L0C4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

760192:HALHY RS31565
gene id: 760192:HALHY_RS31565
uniprot id: F4L6A2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

760192:HALHY RS03310
gene id: 760192:HALHY_RS03310
uniprot id: F4L1M6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

760192:HALHY RS29895
gene id: 760192:HALHY_RS29895
uniprot id: F4L0C5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

760192:HALHY RS13135
gene id: 760192:HALHY_RS13135
uniprot id: F4KZP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

760192:HALHY RS35100
gene id: 760192:HALHY_RS35100
uniprot id: F4L726
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

760192:HALHY RS04680
gene id: 760192:HALHY_RS04680
uniprot id: F4L6F0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

760192:HALHY RS14975
gene id: 760192:HALHY_RS14975
uniprot id: F4L5H7
names: Similarity
messages: Belongs to the arginase family.

760192:HALHY RS19305
gene id: 760192:HALHY_RS19305
uniprot id: F4L286
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS18130
gene id: 760192:HALHY_RS18130
uniprot id: F4KYR8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

760192:HALHY RS07650
gene id: 760192:HALHY_RS07650
uniprot id: F4KYH4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS29795
gene id: 760192:HALHY_RS29795
uniprot id: F4L0A6
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

760192:HALHY RS15335
gene id: 760192:HALHY_RS15335
uniprot id: F4L6S7
names: Similarity
messages: Belongs to the peptidase S66 family.

760192:HALHY RS23315
gene id: 760192:HALHY_RS23315
uniprot id: F4KVN0
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

760192:HALHY RS03500
gene id: 760192:HALHY_RS03500
uniprot id: F4L2P4
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

760192:HALHY RS20815
gene id: 760192:HALHY_RS20815
uniprot id: F4L4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

760192:HALHY RS02550
gene id: 760192:HALHY_RS02550
uniprot id: F4KZC1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS11740
gene id: 760192:HALHY_RS11740
uniprot id: F4KV87
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS15865
gene id: 760192:HALHY_RS15865
uniprot id: F4KQP1
names: Similarity
messages: Belongs to the peptidase S9C family.

760192:HALHY RS21315
gene id: 760192:HALHY_RS21315
uniprot id: F4L721
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.
messages: Membrane

760192:HALHY RS03000
gene id: 760192:HALHY_RS03000
uniprot id: F4L0J9
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

760192:HALHY RS22215
gene id: 760192:HALHY_RS22215
uniprot id: F4KQY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

760192:HALHY RS01490
gene id: 760192:HALHY_RS01490
uniprot id: F4KW08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

760192:HALHY RS11340
gene id: 760192:HALHY_RS11340
uniprot id: F4KU36
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

760192:HALHY RS34330
gene id: 760192:HALHY_RS34330
uniprot id: F4KX32
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

760192:HALHY RS17165
gene id: 760192:HALHY_RS17165
uniprot id: F4KVF7
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS09810
gene id: 760192:HALHY_RS09810
uniprot id: F4L6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

760192:HALHY RS24080
gene id: 760192:HALHY_RS24080
uniprot id: F4KXX7
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS01675
gene id: 760192:HALHY_RS01675
uniprot id: F4KW45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

760192:HALHY RS22330
gene id: 760192:HALHY_RS22330
uniprot id: F4KS50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

760192:HALHY RS26030
gene id: 760192:HALHY_RS26030
uniprot id: F4L4S4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

760192:HALHY RS31655
gene id: 760192:HALHY_RS31655
uniprot id: F4L7F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

760192:HALHY RS29400
gene id: 760192:HALHY_RS29400
uniprot id: F4KZ45
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

760192:HALHY RS02435
gene id: 760192:HALHY_RS02435
uniprot id: F4KU41
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

760192:HALHY RS24455
gene id: 760192:HALHY_RS24455
uniprot id: F4KZ23
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS31805
gene id: 760192:HALHY_RS31805
uniprot id: F4L7J0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

760192:HALHY RS23720
gene id: 760192:HALHY_RS23720
uniprot id: F4KWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

760192:HALHY RS21015
gene id: 760192:HALHY_RS21015
uniprot id: F4L5S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

760192:HALHY RS27620
gene id: 760192:HALHY_RS27620
uniprot id: F4KSD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

760192:HALHY RS21795
gene id: 760192:HALHY_RS21795
uniprot id: F4KPU2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS11065
gene id: 760192:HALHY_RS11065
uniprot id: F4KT12
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

760192:HALHY RS22570
gene id: 760192:HALHY_RS22570
uniprot id: F4KTD1
names: Similarity
messages: Belongs to the peptidase C1 family.

760192:HALHY RS19915
gene id: 760192:HALHY_RS19915
uniprot id: F4L4E5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS07605
gene id: 760192:HALHY_RS07605
uniprot id: F4KYG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS05465
gene id: 760192:HALHY_RS05465
uniprot id: F4KRJ3
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS07320
gene id: 760192:HALHY_RS07320
uniprot id: F4KXE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

760192:HALHY RS20040
gene id: 760192:HALHY_RS20040
uniprot id: F4L5K4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

760192:HALHY RS16370
gene id: 760192:HALHY_RS16370
uniprot id: F4KS29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

760192:HALHY RS02780
gene id: 760192:HALHY_RS02780
uniprot id: F4L0F6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

760192:HALHY RS17225
gene id: 760192:HALHY_RS17225
uniprot id: F4KVG8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760192:HALHY RS30950
gene id: 760192:HALHY_RS30950
uniprot id: F4L4T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

760192:HALHY RS22375
gene id: 760192:HALHY_RS22375
uniprot id: F4KS59
names: Similarity
messages: Belongs to the FMO family.

760192:HALHY RS15050
gene id: 760192:HALHY_RS15050
uniprot id: F4L5J2
names: Similarity
messages: Belongs to the threonine synthase family.

760192:HALHY RS31300
gene id: 760192:HALHY_RS31300
uniprot id: F4L650
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

760192:HALHY RS13090
gene id: 760192:HALHY_RS13090
uniprot id: F4KZN4
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS13705
gene id: 760192:HALHY_RS13705
uniprot id: F4L0Y9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS23750
gene id: 760192:HALHY_RS23750
uniprot id: F4KWU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

760192:HALHY RS24095
gene id: 760192:HALHY_RS24095
uniprot id: F4KXY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS04780
gene id: 760192:HALHY_RS04780
uniprot id: F4KP58
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS03235
gene id: 760192:HALHY_RS03235
uniprot id: F4L1L1
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS04025
gene id: 760192:HALHY_RS04025
uniprot id: F4L3V3
names: Similarity
messages: Belongs to the arginine deiminase family.

760192:HALHY RS11895
gene id: 760192:HALHY_RS11895
uniprot id: F4KVB7
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS11475
gene id: 760192:HALHY_RS11475
uniprot id: F4KU64
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS22425
gene id: 760192:HALHY_RS22425
uniprot id: F4KS70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

760192:HALHY RS24545
gene id: 760192:HALHY_RS24545
uniprot id: F4L017
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS01680
gene id: 760192:HALHY_RS01680
uniprot id: F4KW46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

760192:HALHY RS11310
gene id: 760192:HALHY_RS11310
uniprot id: F4KT59
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS12430
gene id: 760192:HALHY_RS12430
uniprot id: F4KXH1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS15860
gene id: 760192:HALHY_RS15860
uniprot id: F4KQP0
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS01465
gene id: 760192:HALHY_RS01465
uniprot id: F4KW02
names: Subunit
messages: Homodimer.

760192:HALHY RS26910
gene id: 760192:HALHY_RS26910
uniprot id: F4KPZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

760192:HALHY RS13655
gene id: 760192:HALHY_RS13655
uniprot id: F4L0X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS23835
gene id: 760192:HALHY_RS23835
uniprot id: F4KWV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

760192:HALHY RS15675
gene id: 760192:HALHY_RS15675
uniprot id: F4KPN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

760192:HALHY RS11615
gene id: 760192:HALHY_RS11615
uniprot id: F4KU91
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS27260
gene id: 760192:HALHY_RS27260
uniprot id: F4KR30
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

760192:HALHY RS15095
gene id: 760192:HALHY_RS15095
uniprot id: F4L6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

760192:HALHY RS07220
gene id: 760192:HALHY_RS07220
uniprot id: F4KXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS01705
gene id: 760192:HALHY_RS01705
uniprot id: F4KW51
names: Similarity
messages: Belongs to the transketolase family.

760192:HALHY RS20760
gene id: 760192:HALHY_RS20760
uniprot id: F4L4I6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS16475
gene id: 760192:HALHY_RS16475
uniprot id: F4KT80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS02765
gene id: 760192:HALHY_RS02765
uniprot id: F4L0F2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760192:HALHY RS30575
gene id: 760192:HALHY_RS30575
uniprot id: F4L2L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

760192:HALHY RS07515
gene id: 760192:HALHY_RS07515
uniprot id: F4KYE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

760192:HALHY RS22225
gene id: 760192:HALHY_RS22225
uniprot id: F4KQZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

760192:HALHY RS28745
gene id: 760192:HALHY_RS28745
uniprot id: F4KWW7
names: Similarity
messages: Belongs to the peptidase S8 family.

760192:HALHY RS31870
gene id: 760192:HALHY_RS31870
uniprot id: F4L7K2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

760192:HALHY RS17790
gene id: 760192:HALHY_RS17790
uniprot id: F4KXN5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS09110
gene id: 760192:HALHY_RS09110
uniprot id: F4L3Y2
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS22940
gene id: 760192:HALHY_RS22940
uniprot id: F4KUH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

760192:HALHY RS19345
gene id: 760192:HALHY_RS19345
uniprot id: F4L294
names: Similarity
messages: Belongs to the group II decarboxylase family.

760192:HALHY RS22910
gene id: 760192:HALHY_RS22910
uniprot id: F4KUH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

760192:HALHY RS16950
gene id: 760192:HALHY_RS16950
uniprot id: F4KUF0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

760192:HALHY RS23800
gene id: 760192:HALHY_RS23800
uniprot id: F4KWV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

760192:HALHY RS07025
gene id: 760192:HALHY_RS07025
uniprot id: F4KWA3
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS34040
gene id: 760192:HALHY_RS34040
uniprot id: F4L8B6
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS01455
gene id: 760192:HALHY_RS01455
uniprot id: F4KW00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

760192:HALHY RS22535
gene id: 760192:HALHY_RS22535
uniprot id: F4KS92
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS09015
gene id: 760192:HALHY_RS09015
uniprot id: F4L301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

760192:HALHY RS09145
gene id: 760192:HALHY_RS09145
uniprot id: F4L3Y9
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

760192:HALHY RS24410
gene id: 760192:HALHY_RS24410
uniprot id: F4KZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

760192:HALHY RS07990
gene id: 760192:HALHY_RS07990
uniprot id: F4KZL0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS05905
gene id: 760192:HALHY_RS05905
uniprot id: F4KSW1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

760192:HALHY RS23600
gene id: 760192:HALHY_RS23600
uniprot id: F4KWR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

760192:HALHY RS24555
gene id: 760192:HALHY_RS24555
uniprot id: F4L019
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

760192:HALHY RS20130
gene id: 760192:HALHY_RS20130
uniprot id: F4L5M2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

760192:HALHY RS30945
gene id: 760192:HALHY_RS30945
uniprot id: F4L3P9
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

760192:HALHY RS17170
gene id: 760192:HALHY_RS17170
uniprot id: F4KVF8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS25270
gene id: 760192:HALHY_RS25270
uniprot id: F4L2B6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

760192:HALHY RS00530
gene id: 760192:HALHY_RS00530
uniprot id: F4KSQ5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

760192:HALHY RS30790
gene id: 760192:HALHY_RS30790
uniprot id: F4L3M4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS29160
gene id: 760192:HALHY_RS29160
uniprot id: F4KY25
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

760192:HALHY RS29960
gene id: 760192:HALHY_RS29960
uniprot id: F4L0D8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS27850
gene id: 760192:HALHY_RS27850
uniprot id: F4KTL4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

760192:HALHY RS24100
gene id: 760192:HALHY_RS24100
uniprot id: F4KXY2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

760192:HALHY RS12290
gene id: 760192:HALHY_RS12290
uniprot id: F4KWG7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

760192:HALHY RS14100
gene id: 760192:HALHY_RS14100
uniprot id: F4L314
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

760192:HALHY RS32675
gene id: 760192:HALHY_RS32675
uniprot id: F4KSJ3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS03280
gene id: 760192:HALHY_RS03280
uniprot id: F4L1M0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS32090
gene id: 760192:HALHY_RS32090
uniprot id: F4KQ66
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

760192:HALHY RS04690
gene id: 760192:HALHY_RS04690
uniprot id: F4L6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

760192:HALHY RS31875
gene id: 760192:HALHY_RS31875
uniprot id: F4L7K3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

760192:HALHY RS21460
gene id: 760192:HALHY_RS21460
uniprot id: F4L750
names: Similarity
messages: Belongs to the aspartokinase family.

760192:HALHY RS22815
gene id: 760192:HALHY_RS22815
uniprot id: F4KTI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

760192:HALHY RS21225
gene id: 760192:HALHY_RS21225
uniprot id: F4L5W9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

760192:HALHY RS21180
gene id: 760192:HALHY_RS21180
uniprot id: F4L5W0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS19250
gene id: 760192:HALHY_RS19250
uniprot id: F4L275
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS22220
gene id: 760192:HALHY_RS22220
uniprot id: F4KQZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

760192:HALHY RS12945
gene id: 760192:HALHY_RS12945
uniprot id: F4KYN7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

760192:HALHY RS17095
gene id: 760192:HALHY_RS17095
uniprot id: F4KVE3
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS14935
gene id: 760192:HALHY_RS14935
uniprot id: F4L5G9
names: Similarity
messages: Belongs to the peptidase S8 family.

760192:HALHY RS23895
gene id: 760192:HALHY_RS23895
uniprot id: F4KXU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

760192:HALHY RS20940
gene id: 760192:HALHY_RS20940
uniprot id: F4L4M2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS13440
gene id: 760192:HALHY_RS13440
uniprot id: F4L0T6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

760192:HALHY RS02905
gene id: 760192:HALHY_RS02905
uniprot id: F4L0I1
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS32420
gene id: 760192:HALHY_RS32420
uniprot id: F4KRA4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

760192:HALHY RS03265
gene id: 760192:HALHY_RS03265
uniprot id: F4L1L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

760192:HALHY RS18600
gene id: 760192:HALHY_RS18600
uniprot id: F4KZY4
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS04285
gene id: 760192:HALHY_RS04285
uniprot id: F4L539
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

760192:HALHY RS00770
gene id: 760192:HALHY_RS00770
uniprot id: F4KTS1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS30635
gene id: 760192:HALHY_RS30635
uniprot id: F4L2M5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

760192:HALHY RS20930
gene id: 760192:HALHY_RS20930
uniprot id: F4L4M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

760192:HALHY RS16065
gene id: 760192:HALHY_RS16065
uniprot id: F4KRW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

760192:HALHY RS23840
gene id: 760192:HALHY_RS23840
uniprot id: F4KWV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

760192:HALHY RS08005
gene id: 760192:HALHY_RS08005
uniprot id: F4KZL3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

760192:HALHY RS12875
gene id: 760192:HALHY_RS12875
uniprot id: F4KYM7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

760192:HALHY RS27000
gene id: 760192:HALHY_RS27000
uniprot id: F4KQ12
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

760192:HALHY RS30900
gene id: 760192:HALHY_RS30900
uniprot id: F4L3P6
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

760192:HALHY RS11275
gene id: 760192:HALHY_RS11275
uniprot id: F4KT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

760192:HALHY RS23860
gene id: 760192:HALHY_RS23860
uniprot id: F4KXT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

760192:HALHY RS17880
gene id: 760192:HALHY_RS17880
uniprot id: F4KXQ3
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS23355
gene id: 760192:HALHY_RS23355
uniprot id: F4KVN9
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS09800
gene id: 760192:HALHY_RS09800
uniprot id: F4L6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

760192:HALHY RS23690
gene id: 760192:HALHY_RS23690
uniprot id: F4KWS8
names: Similarity
messages: Belongs to the peptidase S41A family.

760192:HALHY RS12565
gene id: 760192:HALHY_RS12565
uniprot id: F4KXJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

760192:HALHY RS23205
gene id: 760192:HALHY_RS23205
uniprot id: F4KVK7
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS22705
gene id: 760192:HALHY_RS22705
uniprot id: F4KTF7
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS12265
gene id: 760192:HALHY_RS12265
uniprot id: F4KWG2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760192:HALHY RS08950
gene id: 760192:HALHY_RS08950
uniprot id: F4L2Z2
names: Similarity
messages: Belongs to the Dps family.

760192:HALHY RS13770
gene id: 760192:HALHY_RS13770
uniprot id: F4L1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

760192:HALHY RS02625
gene id: 760192:HALHY_RS02625
uniprot id: F4KZE0
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS31325
gene id: 760192:HALHY_RS31325
uniprot id: F4L655
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

760192:HALHY RS24395
gene id: 760192:HALHY_RS24395
uniprot id: F4KZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS02420
gene id: 760192:HALHY_RS02420
uniprot id: F4KZ94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

760192:HALHY RS33140
gene id: 760192:HALHY_RS33140
uniprot id: F4L7T1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS16780
gene id: 760192:HALHY_RS16780
uniprot id: F4KUB7
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS02480
gene id: 760192:HALHY_RS02480
uniprot id: F4KZA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

760192:HALHY RS07215
gene id: 760192:HALHY_RS07215
uniprot id: F4KXC1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

760192:HALHY RS00460
gene id: 760192:HALHY_RS00460
uniprot id: F4KSP1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

760192:HALHY RS00185
gene id: 760192:HALHY_RS00185
uniprot id: F4KRG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

760192:HALHY RS00970
gene id: 760192:HALHY_RS00970
uniprot id: F4KTW1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS04225
gene id: 760192:HALHY_RS04225
uniprot id: F4L526
names: Similarity
messages: Belongs to the LOG family.

760192:HALHY RS07595
gene id: 760192:HALHY_RS07595
uniprot id: F4KYG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

760192:HALHY RS31275
gene id: 760192:HALHY_RS31275
uniprot id: F4L645
names: Subunit
messages: Monomer.

760192:HALHY RS28475
gene id: 760192:HALHY_RS28475
uniprot id: F4KVU0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS14660
gene id: 760192:HALHY_RS14660
uniprot id: F4L481
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS05645
gene id: 760192:HALHY_RS05645
uniprot id: F4KRM8
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS24550
gene id: 760192:HALHY_RS24550
uniprot id: F4L018
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Belongs to the glycosyl hydrolase 53 family.

760192:HALHY RS23295
gene id: 760192:HALHY_RS23295
uniprot id: F4KVM6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

760192:HALHY RS31765
gene id: 760192:HALHY_RS31765
uniprot id: F4L7I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

760192:HALHY RS05765
gene id: 760192:HALHY_RS05765
uniprot id: F4KRQ1
names: Subcellular Location Annotation
messages: Cytoplasm

760192:HALHY RS26630
gene id: 760192:HALHY_RS26630
uniprot id: F4L7B6
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

760192:HALHY RS26005
gene id: 760192:HALHY_RS26005
uniprot id: F4L4R9
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

760192:HALHY RS09775
gene id: 760192:HALHY_RS09775
uniprot id: F4L6J1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

760192:HALHY RS16570
gene id: 760192:HALHY_RS16570
uniprot id: F4KT99
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS09265
gene id: 760192:HALHY_RS09265
uniprot id: F4L413
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

760192:HALHY RS07200
gene id: 760192:HALHY_RS07200
uniprot id: F4KXB7
names: Similarity
messages: Belongs to the peptidase C1 family.

760192:HALHY RS22245
gene id: 760192:HALHY_RS22245
uniprot id: F4KS35
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS02400
gene id: 760192:HALHY_RS02400
uniprot id: F4KYC2
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

760192:HALHY RS27650
gene id: 760192:HALHY_RS27650
uniprot id: F4KSE5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

760192:HALHY RS22945
gene id: 760192:HALHY_RS22945
uniprot id: F4KUH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

760192:HALHY RS20155
gene id: 760192:HALHY_RS20155
uniprot id: F4L5M7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS25880
gene id: 760192:HALHY_RS25880
uniprot id: F4L4P3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

760192:HALHY RS07695
gene id: 760192:HALHY_RS07695
uniprot id: F4KYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

760192:HALHY RS16375
gene id: 760192:HALHY_RS16375
uniprot id: F4KS30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

760192:HALHY RS19455
gene id: 760192:HALHY_RS19455
uniprot id: F4L391
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS13930
gene id: 760192:HALHY_RS13930
uniprot id: F4L206
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

760192:HALHY RS06575
gene id: 760192:HALHY_RS06575
uniprot id: F4KV33
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS11545
gene id: 760192:HALHY_RS11545
uniprot id: F4KU78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the nitroreductase family.
messages: Catalyzes the dehalogenation of halotyrosines such as 3-iodo-L-tyrosine and 3,5-diiodo-L-tyrosine (PubMed:24153409, PubMed:28157283). Likely to also catalyze the dehalogenation of other halotyrosines such as 3-bromo-L-tyrosine, 3-chloro-L-tyrosine and 3-iodo-L-tyrosine (By similarity). Activity towards 3-iodo-L-tyrosine is much stronger than activity towards 3,5-diiodo-L-tyrosine and 2-iodophenol (PubMed:28157283, PubMed:24153409).
messages: Homodimer.

760192:HALHY RS20225
gene id: 760192:HALHY_RS20225
uniprot id: F4L5P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

760192:HALHY RS14325
gene id: 760192:HALHY_RS14325
uniprot id: F4L354
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS26330
gene id: 760192:HALHY_RS26330
uniprot id: F4L622
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

760192:HALHY RS35935
gene id: 760192:HALHY_RS35935
uniprot id: F4KQR0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS20580
gene id: 760192:HALHY_RS20580
uniprot id: F4L6Z5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS15770
gene id: 760192:HALHY_RS15770
uniprot id: F4KQM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

760192:HALHY RS18170
gene id: 760192:HALHY_RS18170
uniprot id: F4KYS6
names: Similarity
messages: Belongs to the GbsR family.

760192:HALHY RS25745
gene id: 760192:HALHY_RS25745
uniprot id: F4L3I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

760192:HALHY RS15040
gene id: 760192:HALHY_RS15040
uniprot id: F4L5J0
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

760192:HALHY RS17525
gene id: 760192:HALHY_RS17525
uniprot id: F4KWK2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760192:HALHY RS02035
gene id: 760192:HALHY_RS02035
uniprot id: F4KX86
names: Similarity
messages: Belongs to the glutamine synthetase family.

760192:HALHY RS02010
gene id: 760192:HALHY_RS02010
uniprot id: F4KX81
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS08210
gene id: 760192:HALHY_RS08210
uniprot id: F4L0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS06840
gene id: 760192:HALHY_RS06840
uniprot id: F4KW65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS02115
gene id: 760192:HALHY_RS02115
uniprot id: F4KY66
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

760192:HALHY RS22860
gene id: 760192:HALHY_RS22860
uniprot id: F4KTI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS27435
gene id: 760192:HALHY_RS27435
uniprot id: F4KSA1
names: Similarity
messages: Belongs to the AHA1 family.

760192:HALHY RS27820
gene id: 760192:HALHY_RS27820
uniprot id: F4KTK8
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS33595
gene id: 760192:HALHY_RS33595
uniprot id: F4L828
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

760192:HALHY RS21395
gene id: 760192:HALHY_RS21395
uniprot id: F4L737
names: Similarity
messages: Belongs to the group II decarboxylase family.

760192:HALHY RS24795
gene id: 760192:HALHY_RS24795
uniprot id: F4L069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

760192:HALHY RS19610
gene id: 760192:HALHY_RS19610
uniprot id: F4L3B9
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS03355
gene id: 760192:HALHY_RS03355
uniprot id: F4L1N3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS04665
gene id: 760192:HALHY_RS04665
uniprot id: F4L6E7
names: Similarity
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.

760192:HALHY RS25975
gene id: 760192:HALHY_RS25975
uniprot id: F4L4R3
names: Cofactor
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

760192:HALHY RS13030
gene id: 760192:HALHY_RS13030
uniprot id: F4KZM3
names: Similarity
messages: Belongs to the sigma-54 factor family.

760192:HALHY RS17205
gene id: 760192:HALHY_RS17205
uniprot id: F4KVG4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

760192:HALHY RS23070
gene id: 760192:HALHY_RS23070
uniprot id: F4KUK0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

760192:HALHY RS20965
gene id: 760192:HALHY_RS20965
uniprot id: F4L5R8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

760192:HALHY RS14005
gene id: 760192:HALHY_RS14005
uniprot id: F4L223
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS26435
gene id: 760192:HALHY_RS26435
uniprot id: F4L778
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS16810
gene id: 760192:HALHY_RS16810
uniprot id: F4KUC3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

760192:HALHY RS17215
gene id: 760192:HALHY_RS17215
uniprot id: F4KVG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

760192:HALHY RS26570
gene id: 760192:HALHY_RS26570
uniprot id: F4L7A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS23885
gene id: 760192:HALHY_RS23885
uniprot id: F4KXU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

760192:HALHY RS21425
gene id: 760192:HALHY_RS21425
uniprot id: F4L743
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

760192:HALHY RS00905
gene id: 760192:HALHY_RS00905
uniprot id: F4KTU8
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

760192:HALHY RS32540
gene id: 760192:HALHY_RS32540
uniprot id: F4KSG5
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

760192:HALHY RS05510
gene id: 760192:HALHY_RS05510
uniprot id: F4KRK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

760192:HALHY RS30660
gene id: 760192:HALHY_RS30660
uniprot id: F4L3J9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

760192:HALHY RS15745
gene id: 760192:HALHY_RS15745
uniprot id: F4KQL8
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS13795
gene id: 760192:HALHY_RS13795
uniprot id: F4L1X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

760192:HALHY RS01120
gene id: 760192:HALHY_RS01120
uniprot id: F4KUV9
names: Similarity
messages: Belongs to the peptidase M1 family.

760192:HALHY RS26355
gene id: 760192:HALHY_RS26355
uniprot id: F4L627
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS16165
gene id: 760192:HALHY_RS16165
uniprot id: F4KRY8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

760192:HALHY RS12680
gene id: 760192:HALHY_RS12680
uniprot id: F4KYI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

760192:HALHY RS35080
gene id: 760192:HALHY_RS35080
uniprot id: F4L5V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS24845
gene id: 760192:HALHY_RS24845
uniprot id: F4L156
names: Subcellular Location Annotation
messages: Cytoplasm

760192:HALHY RS12650
gene id: 760192:HALHY_RS12650
uniprot id: F4KXL6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS23645
gene id: 760192:HALHY_RS23645
uniprot id: F4KWR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

760192:HALHY RS33090
gene id: 760192:HALHY_RS33090
uniprot id: F4L7S0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760192:HALHY RS25530
gene id: 760192:HALHY_RS25530
uniprot id: F4L3E4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS09555
gene id: 760192:HALHY_RS09555
uniprot id: F4L5A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

760192:HALHY RS01730
gene id: 760192:HALHY_RS01730
uniprot id: F4KX26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS03595
gene id: 760192:HALHY_RS03595
uniprot id: F4L2R3
names: Similarity
messages: Belongs to the UPF0175 family.

760192:HALHY RS06055
gene id: 760192:HALHY_RS06055
uniprot id: F4KSY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

760192:HALHY RS22055
gene id: 760192:HALHY_RS22055
uniprot id: F4KQV8
names: Similarity
messages: Belongs to the UxaA family.

760192:HALHY RS32560
gene id: 760192:HALHY_RS32560
uniprot id: F4KSG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

760192:HALHY RS07265
gene id: 760192:HALHY_RS07265
uniprot id: F4KXD1
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS29215
gene id: 760192:HALHY_RS29215
uniprot id: F4KY36
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS32000
gene id: 760192:HALHY_RS32000
uniprot id: F4KQ48
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS28380
gene id: 760192:HALHY_RS28380
uniprot id: F4KVS1
names: Similarity
messages: Belongs to the universal stress protein A family.

760192:HALHY RS02410
gene id: 760192:HALHY_RS02410
uniprot id: F4KZ92
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

760192:HALHY RS10190
gene id: 760192:HALHY_RS10190
uniprot id: F4KPF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

760192:HALHY RS12665
gene id: 760192:HALHY_RS12665
uniprot id: F4KXL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

760192:HALHY RS14995
gene id: 760192:HALHY_RS14995
uniprot id: F4L5I1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

760192:HALHY RS23585
gene id: 760192:HALHY_RS23585
uniprot id: F4KWQ7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

760192:HALHY RS24245
gene id: 760192:HALHY_RS24245
uniprot id: F4KYY3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

760192:HALHY RS30085
gene id: 760192:HALHY_RS30085
uniprot id: F4L1D7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

760192:HALHY RS00930
gene id: 760192:HALHY_RS00930
uniprot id: F4KTV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

760192:HALHY RS29830
gene id: 760192:HALHY_RS29830
uniprot id: F4L0B3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

760192:HALHY RS06380
gene id: 760192:HALHY_RS06380
uniprot id: F4KU24
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS19385
gene id: 760192:HALHY_RS19385
uniprot id: F4L375
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

760192:HALHY RS20245
gene id: 760192:HALHY_RS20245
uniprot id: F4L5P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS01770
gene id: 760192:HALHY_RS01770
uniprot id: F4KX34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

760192:HALHY RS19605
gene id: 760192:HALHY_RS19605
uniprot id: F4L3B8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS16290
gene id: 760192:HALHY_RS16290
uniprot id: F4KS13
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS03470
gene id: 760192:HALHY_RS03470
uniprot id: F4L2N7
names: Subcellular Location Annotation
messages: Secreted

760192:HALHY RS02175
gene id: 760192:HALHY_RS02175
uniprot id: F4KY78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

760192:HALHY RS29410
gene id: 760192:HALHY_RS29410
uniprot id: F4KZ47
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

760192:HALHY RS01845
gene id: 760192:HALHY_RS01845
uniprot id: F4KX49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

760192:HALHY RS11670
gene id: 760192:HALHY_RS11670
uniprot id: F4KV74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

760192:HALHY RS15355
gene id: 760192:HALHY_RS15355
uniprot id: F4L6T1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

760192:HALHY RS15325
gene id: 760192:HALHY_RS15325
uniprot id: F4L6S5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS15900
gene id: 760192:HALHY_RS15900
uniprot id: F4KQP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS31435
gene id: 760192:HALHY_RS31435
uniprot id: F4L676
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

760192:HALHY RS17700
gene id: 760192:HALHY_RS17700
uniprot id: F4KWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

760192:HALHY RS28015
gene id: 760192:HALHY_RS28015
uniprot id: F4KTP7
names: Similarity
messages: Belongs to the peptidase C10 family.

760192:HALHY RS28955
gene id: 760192:HALHY_RS28955
uniprot id: F4KX09
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

760192:HALHY RS21275
gene id: 760192:HALHY_RS21275
uniprot id: F4L713
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

760192:HALHY RS00425
gene id: 760192:HALHY_RS00425
uniprot id: F4KSN4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS05455
gene id: 760192:HALHY_RS05455
uniprot id: F4KRJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS31690
gene id: 760192:HALHY_RS31690
uniprot id: F4L7G4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

760192:HALHY RS16300
gene id: 760192:HALHY_RS16300
uniprot id: F4KS15
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS11970
gene id: 760192:HALHY_RS11970
uniprot id: F4KVD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS14630
gene id: 760192:HALHY_RS14630
uniprot id: F4L475
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS31425
gene id: 760192:HALHY_RS31425
uniprot id: F4L674
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS11730
gene id: 760192:HALHY_RS11730
uniprot id: F4KV85
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

760192:HALHY RS12345
gene id: 760192:HALHY_RS12345
uniprot id: F4KXF6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS26845
gene id: 760192:HALHY_RS26845
uniprot id: F4KPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

760192:HALHY RS25565
gene id: 760192:HALHY_RS25565
uniprot id: F4L3F1
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS23890
gene id: 760192:HALHY_RS23890
uniprot id: F4KXU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

760192:HALHY RS11720
gene id: 760192:HALHY_RS11720
uniprot id: F4KV83
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS25150
gene id: 760192:HALHY_RS25150
uniprot id: F4L296
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS28930
gene id: 760192:HALHY_RS28930
uniprot id: F4KX04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

760192:HALHY RS14980
gene id: 760192:HALHY_RS14980
uniprot id: F4L5H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

760192:HALHY RS14875
gene id: 760192:HALHY_RS14875
uniprot id: F4L5F7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

760192:HALHY RS01645
gene id: 760192:HALHY_RS01645
uniprot id: F4KW39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760192:HALHY RS10120
gene id: 760192:HALHY_RS10120
uniprot id: F4KPE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

760192:HALHY RS28505
gene id: 760192:HALHY_RS28505
uniprot id: F4KVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS15405
gene id: 760192:HALHY_RS15405
uniprot id: F4L6U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

760192:HALHY RS15440
gene id: 760192:HALHY_RS15440
uniprot id: F4KPJ0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS32730
gene id: 760192:HALHY_RS32730
uniprot id: F4KSK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

760192:HALHY RS27325
gene id: 760192:HALHY_RS27325
uniprot id: F4KR43
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS16690
gene id: 760192:HALHY_RS16690
uniprot id: F4KTC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

760192:HALHY RS19640
gene id: 760192:HALHY_RS19640
uniprot id: F4L3C5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS04970
gene id: 760192:HALHY_RS04970
uniprot id: F4KP94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

760192:HALHY RS31145
gene id: 760192:HALHY_RS31145
uniprot id: F4L4X6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

760192:HALHY RS22635
gene id: 760192:HALHY_RS22635
uniprot id: F4KTE4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

760192:HALHY RS05015
gene id: 760192:HALHY_RS05015
uniprot id: F4KPA3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

760192:HALHY RS29840
gene id: 760192:HALHY_RS29840
uniprot id: F4L0B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS19285
gene id: 760192:HALHY_RS19285
uniprot id: F4L282
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

760192:HALHY RS16025
gene id: 760192:HALHY_RS16025
uniprot id: F4KQS3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

760192:HALHY RS25045
gene id: 760192:HALHY_RS25045
uniprot id: F4L196
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

760192:HALHY RS04735
gene id: 760192:HALHY_RS04735
uniprot id: F4L6G1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

760192:HALHY RS19135
gene id: 760192:HALHY_RS19135
uniprot id: F4L252
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

760192:HALHY RS29745
gene id: 760192:HALHY_RS29745
uniprot id: F4L096
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

760192:HALHY RS23775
gene id: 760192:HALHY_RS23775
uniprot id: F4KWU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

760192:HALHY RS22620
gene id: 760192:HALHY_RS22620
uniprot id: F4KTE1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

760192:HALHY RS04035
gene id: 760192:HALHY_RS04035
uniprot id: F4L3V5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS09075
gene id: 760192:HALHY_RS09075
uniprot id: F4L3X6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

760192:HALHY RS23055
gene id: 760192:HALHY_RS23055
uniprot id: F4KUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

760192:HALHY RS09995
gene id: 760192:HALHY_RS09995
uniprot id: F4L6N0
names: Similarity
messages: Belongs to the GARS family.

760192:HALHY RS22870
gene id: 760192:HALHY_RS22870
uniprot id: F4KUG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

760192:HALHY RS07405
gene id: 760192:HALHY_RS07405
uniprot id: F4KYC7
names: Similarity
messages: Belongs to the FGGY kinase family.

760192:HALHY RS03705
gene id: 760192:HALHY_RS03705
uniprot id: F4L2T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

760192:HALHY RS09090
gene id: 760192:HALHY_RS09090
uniprot id: F4L3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS12585
gene id: 760192:HALHY_RS12585
uniprot id: F4KXK2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

760192:HALHY RS12725
gene id: 760192:HALHY_RS12725
uniprot id: F4KYJ7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

760192:HALHY RS01785
gene id: 760192:HALHY_RS01785
uniprot id: F4KX37
names: Similarity
messages: Belongs to the ribulokinase family.

760192:HALHY RS25560
gene id: 760192:HALHY_RS25560
uniprot id: F4L3F0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS27915
gene id: 760192:HALHY_RS27915
uniprot id: F4KTM6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS26150
gene id: 760192:HALHY_RS26150
uniprot id: F4L5Y6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS05805
gene id: 760192:HALHY_RS05805
uniprot id: F4KSU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Belongs to the heat shock protein 70 family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

760192:HALHY RS00685
gene id: 760192:HALHY_RS00685
uniprot id: F4KTQ4
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

760192:HALHY RS09370
gene id: 760192:HALHY_RS09370
uniprot id: F4L570
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

760192:HALHY RS10315
gene id: 760192:HALHY_RS10315
uniprot id: F4KPI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

760192:HALHY RS19275
gene id: 760192:HALHY_RS19275
uniprot id: F4L280
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS23325
gene id: 760192:HALHY_RS23325
uniprot id: F4KVN3
names: Similarity
messages: Belongs to the peptidase S51 family.

760192:HALHY RS29285
gene id: 760192:HALHY_RS29285
uniprot id: F4KY50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

760192:HALHY RS17360
gene id: 760192:HALHY_RS17360
uniprot id: F4KVJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS09550
gene id: 760192:HALHY_RS09550
uniprot id: F4L5A6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760192:HALHY RS28655
gene id: 760192:HALHY_RS28655
uniprot id: F4KVX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS24435
gene id: 760192:HALHY_RS24435
uniprot id: F4KZ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

760192:HALHY RS16385
gene id: 760192:HALHY_RS16385
uniprot id: F4KS32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

760192:HALHY RS16120
gene id: 760192:HALHY_RS16120
uniprot id: F4KRX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

760192:HALHY RS01315
gene id: 760192:HALHY_RS01315
uniprot id: F4KUZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

760192:HALHY RS03060
gene id: 760192:HALHY_RS03060
uniprot id: F4L1H9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

760192:HALHY RS02725
gene id: 760192:HALHY_RS02725
uniprot id: F4L0E4
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

760192:HALHY RS15560
gene id: 760192:HALHY_RS15560
uniprot id: F4KPL6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS14885
gene id: 760192:HALHY_RS14885
uniprot id: F4L5F9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

760192:HALHY RS22775
gene id: 760192:HALHY_RS22775
uniprot id: F4KTH2
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

760192:HALHY RS06470
gene id: 760192:HALHY_RS06470
uniprot id: F4KV12
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS04260
gene id: 760192:HALHY_RS04260
uniprot id: F4L534
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS16555
gene id: 760192:HALHY_RS16555
uniprot id: F4KT96
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS16725
gene id: 760192:HALHY_RS16725
uniprot id: F4KUA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

760192:HALHY RS29040
gene id: 760192:HALHY_RS29040
uniprot id: F4KY01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS30410
gene id: 760192:HALHY_RS30410
uniprot id: F4L2I0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

760192:HALHY RS15915
gene id: 760192:HALHY_RS15915
uniprot id: F4KQQ1
names: Similarity
messages: Belongs to the peptidase M24B family.

760192:HALHY RS14440
gene id: 760192:HALHY_RS14440
uniprot id: F4L438
names: Similarity
messages: Belongs to the ABC transporter superfamily.

760192:HALHY RS05475
gene id: 760192:HALHY_RS05475
uniprot id: F4KRJ5
names: Similarity
messages: Belongs to the fabD family.

760192:HALHY RS25040
gene id: 760192:HALHY_RS25040
uniprot id: F4L195
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

760192:HALHY RS07510
gene id: 760192:HALHY_RS07510
uniprot id: F4KYE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

760192:HALHY RS05590
gene id: 760192:HALHY_RS05590
uniprot id: F4KRL7
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

760192:HALHY RS24565
gene id: 760192:HALHY_RS24565
uniprot id: F4L021
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS27765
gene id: 760192:HALHY_RS27765
uniprot id: F4KTJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

760192:HALHY RS01330
gene id: 760192:HALHY_RS01330
uniprot id: F4KUZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

760192:HALHY RS29935
gene id: 760192:HALHY_RS29935
uniprot id: F4L0D3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

760192:HALHY RS07325
gene id: 760192:HALHY_RS07325
uniprot id: F4KXE2
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS35385
gene id: 760192:HALHY_RS35385
uniprot id: F4KTN6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS09440
gene id: 760192:HALHY_RS09440
uniprot id: F4L584
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

760192:HALHY RS19495
gene id: 760192:HALHY_RS19495
uniprot id: F4L3A0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS06920
gene id: 760192:HALHY_RS06920
uniprot id: F4KW82
names: Similarity
messages: Belongs to the threonine aldolase family.

760192:HALHY RS06165
gene id: 760192:HALHY_RS06165
uniprot id: F4KTY2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS04060
gene id: 760192:HALHY_RS04060
uniprot id: F4L3W0
names: Similarity
messages: Belongs to the ParB family.

760192:HALHY RS27130
gene id: 760192:HALHY_RS27130
uniprot id: F4KR04
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS19675
gene id: 760192:HALHY_RS19675
uniprot id: F4L3D2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS14775
gene id: 760192:HALHY_RS14775
uniprot id: F4L5D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

760192:HALHY RS18915
gene id: 760192:HALHY_RS18915
uniprot id: F4L131
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

760192:HALHY RS16935
gene id: 760192:HALHY_RS16935
uniprot id: F4KUE7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

760192:HALHY RS31955
gene id: 760192:HALHY_RS31955
uniprot id: F4KQ38
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

760192:HALHY RS14815
gene id: 760192:HALHY_RS14815
uniprot id: F4L5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

760192:HALHY RS12710
gene id: 760192:HALHY_RS12710
uniprot id: F4KYJ4
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS16365
gene id: 760192:HALHY_RS16365
uniprot id: F4KS28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

760192:HALHY RS30045
gene id: 760192:HALHY_RS30045
uniprot id: F4L1D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

760192:HALHY RS14930
gene id: 760192:HALHY_RS14930
uniprot id: F4L5G8
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

760192:HALHY RS08755
gene id: 760192:HALHY_RS08755
uniprot id: F4L2V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

760192:HALHY RS10925
gene id: 760192:HALHY_RS10925
uniprot id: F4KRV1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

760192:HALHY RS11230
gene id: 760192:HALHY_RS11230
uniprot id: F4KT44
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS24955
gene id: 760192:HALHY_RS24955
uniprot id: F4L178
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

760192:HALHY RS01800
gene id: 760192:HALHY_RS01800
uniprot id: F4KX40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS06985
gene id: 760192:HALHY_RS06985
uniprot id: F4KW95
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

760192:HALHY RS16305
gene id: 760192:HALHY_RS16305
uniprot id: F4KS16
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS14545
gene id: 760192:HALHY_RS14545
uniprot id: F4L458
names: Similarity
messages: Belongs to the asparagine synthetase family.

760192:HALHY RS29345
gene id: 760192:HALHY_RS29345
uniprot id: F4KZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

760192:HALHY RS05140
gene id: 760192:HALHY_RS05140
uniprot id: F4KQ94
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760192:HALHY RS15520
gene id: 760192:HALHY_RS15520
uniprot id: F4KPK6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS02490
gene id: 760192:HALHY_RS02490
uniprot id: F4KZA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

760192:HALHY RS22765
gene id: 760192:HALHY_RS22765
uniprot id: F4KTH0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

760192:HALHY RS02575
gene id: 760192:HALHY_RS02575
uniprot id: F4KZC7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

760192:HALHY RS10500
gene id: 760192:HALHY_RS10500
uniprot id: F4KQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS02365
gene id: 760192:HALHY_RS02365
uniprot id: F4KYB5
names: Similarity
messages: Belongs to the UPF0311 family.

760192:HALHY RS03305
gene id: 760192:HALHY_RS03305
uniprot id: F4L1M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

760192:HALHY RS30275
gene id: 760192:HALHY_RS30275
uniprot id: F4L1H4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

760192:HALHY RS27010
gene id: 760192:HALHY_RS27010
uniprot id: F4KQ14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

760192:HALHY RS31735
gene id: 760192:HALHY_RS31735
uniprot id: F4L7H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS16090
gene id: 760192:HALHY_RS16090
uniprot id: F4KRX2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS26875
gene id: 760192:HALHY_RS26875
uniprot id: F4KPY7
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS27070
gene id: 760192:HALHY_RS27070
uniprot id: F4KQ25
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

760192:HALHY RS31675
gene id: 760192:HALHY_RS31675
uniprot id: F4L7G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

760192:HALHY RS25780
gene id: 760192:HALHY_RS25780
uniprot id: F4L4M3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

760192:HALHY RS22135
gene id: 760192:HALHY_RS22135
uniprot id: F4KQX3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

760192:HALHY RS32910
gene id: 760192:HALHY_RS32910
uniprot id: F4L7N0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

760192:HALHY RS16830
gene id: 760192:HALHY_RS16830
uniprot id: F4KUC6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS07075
gene id: 760192:HALHY_RS07075
uniprot id: F4KX93
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

760192:HALHY RS17120
gene id: 760192:HALHY_RS17120
uniprot id: F4KVE8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

760192:HALHY RS34425
gene id: 760192:HALHY_RS34425
uniprot id: F4L2N4
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

760192:HALHY RS10130
gene id: 760192:HALHY_RS10130
uniprot id: F4KPE6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

760192:HALHY RS19245
gene id: 760192:HALHY_RS19245
uniprot id: F4L274
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

760192:HALHY RS10970
gene id: 760192:HALHY_RS10970
uniprot id: F4KRW0
names: Similarity
messages: Belongs to the HsdR family.

760192:HALHY RS06740
gene id: 760192:HALHY_RS06740
uniprot id: F4KV67
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

760192:HALHY RS06335
gene id: 760192:HALHY_RS06335
uniprot id: F4KU15
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

760192:HALHY RS10950
gene id: 760192:HALHY_RS10950
uniprot id: F4KRV6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS31625
gene id: 760192:HALHY_RS31625
uniprot id: F4L7F1
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS17210
gene id: 760192:HALHY_RS17210
uniprot id: F4KVG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

760192:HALHY RS27455
gene id: 760192:HALHY_RS27455
uniprot id: F4KSA5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS24570
gene id: 760192:HALHY_RS24570
uniprot id: F4L022
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS03760
gene id: 760192:HALHY_RS03760
uniprot id: F4L3Q5
names: Similarity
messages: Belongs to the IlvD/Edd family.

760192:HALHY RS22100
gene id: 760192:HALHY_RS22100
uniprot id: F4KQW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

760192:HALHY RS13755
gene id: 760192:HALHY_RS13755
uniprot id: F4L1X0
names: Similarity
messages: Belongs to the peptidase M29 family.

760192:HALHY RS01115
gene id: 760192:HALHY_RS01115
uniprot id: F4KUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

760192:HALHY RS22915
gene id: 760192:HALHY_RS22915
uniprot id: F4KUH2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

760192:HALHY RS30595
gene id: 760192:HALHY_RS30595
uniprot id: F4L2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS12670
gene id: 760192:HALHY_RS12670
uniprot id: F4KXM0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

760192:HALHY RS05705
gene id: 760192:HALHY_RS05705
uniprot id: F4KRN9
names: PTM
messages: Binds 1 heme c group covalently per subunit.

760192:HALHY RS27845
gene id: 760192:HALHY_RS27845
uniprot id: F4KTL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

760192:HALHY RS01775
gene id: 760192:HALHY_RS01775
uniprot id: F4KX35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

760192:HALHY RS10820
gene id: 760192:HALHY_RS10820
uniprot id: F4KRT2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS32650
gene id: 760192:HALHY_RS32650
uniprot id: F4KSI8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS04675
gene id: 760192:HALHY_RS04675
uniprot id: F4L6E9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

760192:HALHY RS32805
gene id: 760192:HALHY_RS32805
uniprot id: F4L7K8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS15880
gene id: 760192:HALHY_RS15880
uniprot id: F4KQP4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

760192:HALHY RS28255
gene id: 760192:HALHY_RS28255
uniprot id: F4KUR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

760192:HALHY RS05275
gene id: 760192:HALHY_RS05275
uniprot id: F4KQC0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS09150
gene id: 760192:HALHY_RS09150
uniprot id: F4L3Z0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

760192:HALHY RS15780
gene id: 760192:HALHY_RS15780
uniprot id: F4KQM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

760192:HALHY RS02660
gene id: 760192:HALHY_RS02660
uniprot id: F4KZE7
names: Similarity
messages: Belongs to the peptidase S51 family.

760192:HALHY RS21370
gene id: 760192:HALHY_RS21370
uniprot id: F4L732
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

760192:HALHY RS23605
gene id: 760192:HALHY_RS23605
uniprot id: F4KWR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

760192:HALHY RS14890
gene id: 760192:HALHY_RS14890
uniprot id: F4L5G0
names: Similarity
messages: Belongs to the peptidase C40 family.

760192:HALHY RS31055
gene id: 760192:HALHY_RS31055
uniprot id: F4L4V8
names: Similarity
messages: Belongs to the peptidase M1 family.

760192:HALHY RS16260
gene id: 760192:HALHY_RS16260
uniprot id: F4KS07
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

760192:HALHY RS19175
gene id: 760192:HALHY_RS19175
uniprot id: F4L260
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

760192:HALHY RS17945
gene id: 760192:HALHY_RS17945
uniprot id: F4KXR5
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS10235
gene id: 760192:HALHY_RS10235
uniprot id: F4KPG6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

760192:HALHY RS13345
gene id: 760192:HALHY_RS13345
uniprot id: F4KZT7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS17890
gene id: 760192:HALHY_RS17890
uniprot id: F4KXQ4
names: Similarity
messages: Belongs to the sulfatase family.

760192:HALHY RS01965
gene id: 760192:HALHY_RS01965
uniprot id: F4KX72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS04175
gene id: 760192:HALHY_RS04175
uniprot id: F4L517
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

760192:HALHY RS21920
gene id: 760192:HALHY_RS21920
uniprot id: F4KQT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS15145
gene id: 760192:HALHY_RS15145
uniprot id: F4L6P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

760192:HALHY RS04765
gene id: 760192:HALHY_RS04765
uniprot id: F4L6G7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS06530
gene id: 760192:HALHY_RS06530
uniprot id: F4KV24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

760192:HALHY RS22935
gene id: 760192:HALHY_RS22935
uniprot id: F4KUH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

760192:HALHY RS03260
gene id: 760192:HALHY_RS03260
uniprot id: F4L1L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS31560
gene id: 760192:HALHY_RS31560
uniprot id: F4L6A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

760192:HALHY RS22235
gene id: 760192:HALHY_RS22235
uniprot id: F4KS33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

760192:HALHY RS01685
gene id: 760192:HALHY_RS01685
uniprot id: F4KW47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

760192:HALHY RS26585
gene id: 760192:HALHY_RS26585
uniprot id: F4L7A6
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

760192:HALHY RS09330
gene id: 760192:HALHY_RS09330
uniprot id: F4L425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

760192:HALHY RS17930
gene id: 760192:HALHY_RS17930
uniprot id: F4KXR2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS09905
gene id: 760192:HALHY_RS09905
uniprot id: F4L6L7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

760192:HALHY RS05825
gene id: 760192:HALHY_RS05825
uniprot id: F4KSU5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS21745
gene id: 760192:HALHY_RS21745
uniprot id: F4KPT1
names: Similarity
messages: Belongs to the peptidase S33 family.

760192:HALHY RS12190
gene id: 760192:HALHY_RS12190
uniprot id: F4KWE9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

760192:HALHY RS15575
gene id: 760192:HALHY_RS15575
uniprot id: F4KPL9
names: Similarity
messages: Belongs to the peptidase S41A family.

760192:HALHY RS13730
gene id: 760192:HALHY_RS13730
uniprot id: F4L1W5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

760192:HALHY RS16320
gene id: 760192:HALHY_RS16320
uniprot id: F4KS19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

760192:HALHY RS03340
gene id: 760192:HALHY_RS03340
uniprot id: F4L1N0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS03165
gene id: 760192:HALHY_RS03165
uniprot id: F4L1K1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS31785
gene id: 760192:HALHY_RS31785
uniprot id: F4L7I6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

760192:HALHY RS17740
gene id: 760192:HALHY_RS17740
uniprot id: F4KXM5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS03345
gene id: 760192:HALHY_RS03345
uniprot id: F4L1N1
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS18375
gene id: 760192:HALHY_RS18375
uniprot id: F4KYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS27865
gene id: 760192:HALHY_RS27865
uniprot id: F4KTL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

760192:HALHY RS04210
gene id: 760192:HALHY_RS04210
uniprot id: F4L523
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

760192:HALHY RS14905
gene id: 760192:HALHY_RS14905
uniprot id: F4L5G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

760192:HALHY RS10750
gene id: 760192:HALHY_RS10750
uniprot id: F4KRR8
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

760192:HALHY RS12150
gene id: 760192:HALHY_RS12150
uniprot id: F4KWE1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

760192:HALHY RS17200
gene id: 760192:HALHY_RS17200
uniprot id: F4KVG3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS30250
gene id: 760192:HALHY_RS30250
uniprot id: F4L1G9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

760192:HALHY RS11605
gene id: 760192:HALHY_RS11605
uniprot id: F4KU89
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS13980
gene id: 760192:HALHY_RS13980
uniprot id: F4L218
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS29790
gene id: 760192:HALHY_RS29790
uniprot id: F4L0A5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

760192:HALHY RS31575
gene id: 760192:HALHY_RS31575
uniprot id: F4L6A4
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS19070
gene id: 760192:HALHY_RS19070
uniprot id: F4L238
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

760192:HALHY RS27715
gene id: 760192:HALHY_RS27715
uniprot id: F4KSF9
names: Subcellular Location Annotation
messages: Secreted

760192:HALHY RS02315
gene id: 760192:HALHY_RS02315
uniprot id: F4KYA5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

760192:HALHY RS34930
gene id: 760192:HALHY_RS34930
uniprot id: F4KS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

760192:HALHY RS22075
gene id: 760192:HALHY_RS22075
uniprot id: F4KQW2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS31725
gene id: 760192:HALHY_RS31725
uniprot id: F4L7H2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS06325
gene id: 760192:HALHY_RS06325
uniprot id: F4KU13
names: Similarity
messages: Belongs to the phosphohexose mutase family.

760192:HALHY RS05460
gene id: 760192:HALHY_RS05460
uniprot id: F4KRJ2
names: Similarity
messages: Belongs to the AIR synthase family.

760192:HALHY RS17515
gene id: 760192:HALHY_RS17515
uniprot id: F4KWK0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

760192:HALHY RS16455
gene id: 760192:HALHY_RS16455
uniprot id: F4KT76
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

760192:HALHY RS13245
gene id: 760192:HALHY_RS13245
uniprot id: F4KZR7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

760192:HALHY RS30445
gene id: 760192:HALHY_RS30445
uniprot id: F4L2I7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

760192:HALHY RS11090
gene id: 760192:HALHY_RS11090
uniprot id: F4KT17
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

760192:HALHY RS09045
gene id: 760192:HALHY_RS09045
uniprot id: F4L3X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS31335
gene id: 760192:HALHY_RS31335
uniprot id: F4L657
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS25840
gene id: 760192:HALHY_RS25840
uniprot id: F4L4N5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

760192:HALHY RS31175
gene id: 760192:HALHY_RS31175
uniprot id: F4L4Y2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS28215
gene id: 760192:HALHY_RS28215
uniprot id: F4KUQ9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS22510
gene id: 760192:HALHY_RS22510
uniprot id: F4KS86
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

760192:HALHY RS23180
gene id: 760192:HALHY_RS23180
uniprot id: F4KUM3
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS25285
gene id: 760192:HALHY_RS25285
uniprot id: F4L2B9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

760192:HALHY RS16845
gene id: 760192:HALHY_RS16845
uniprot id: F4KUC9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

760192:HALHY RS07965
gene id: 760192:HALHY_RS07965
uniprot id: F4KZK5
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

760192:HALHY RS26160
gene id: 760192:HALHY_RS26160
uniprot id: F4L5Y8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS26720
gene id: 760192:HALHY_RS26720
uniprot id: F4L7D3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760192:HALHY RS06270
gene id: 760192:HALHY_RS06270
uniprot id: F4KU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS27185
gene id: 760192:HALHY_RS27185
uniprot id: F4KR15
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

760192:HALHY RS26780
gene id: 760192:HALHY_RS26780
uniprot id: F4KPW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

760192:HALHY RS32775
gene id: 760192:HALHY_RS32775
uniprot id: F4KSL1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

760192:HALHY RS21700
gene id: 760192:HALHY_RS21700
uniprot id: F4KPS2
names: Subcellular Location Annotation
messages: Cell inner membrane

760192:HALHY RS17850
gene id: 760192:HALHY_RS17850
uniprot id: F4KXP7
names: Similarity
messages: Belongs to the CapA family.

760192:HALHY RS06130
gene id: 760192:HALHY_RS06130
uniprot id: F4KTX5
names: Similarity
messages: Belongs to the DapA family.

760192:HALHY RS34800
gene id: 760192:HALHY_RS34800
uniprot id: F4KWH3
names: Similarity
messages: Belongs to the peptidase S8 family.

760192:HALHY RS02180
gene id: 760192:HALHY_RS02180
uniprot id: F4KY79
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

760192:HALHY RS27560
gene id: 760192:HALHY_RS27560
uniprot id: F4KSC5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS19680
gene id: 760192:HALHY_RS19680
uniprot id: F4L498
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS19830
gene id: 760192:HALHY_RS19830
uniprot id: F4L4C7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS15785
gene id: 760192:HALHY_RS15785
uniprot id: F4KQM6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

760192:HALHY RS23615
gene id: 760192:HALHY_RS23615
uniprot id: F4KWR3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

760192:HALHY RS22740
gene id: 760192:HALHY_RS22740
uniprot id: F4KTG5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

760192:HALHY RS14740
gene id: 760192:HALHY_RS14740
uniprot id: F4L497
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

760192:HALHY RS21375
gene id: 760192:HALHY_RS21375
uniprot id: F4L733
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

760192:HALHY RS12180
gene id: 760192:HALHY_RS12180
uniprot id: F4KWE7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

760192:HALHY RS19845
gene id: 760192:HALHY_RS19845
uniprot id: F4L4D0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

760192:HALHY RS20065
gene id: 760192:HALHY_RS20065
uniprot id: F4L5K9
names: Similarity
messages: Belongs to the peptidase M1 family.

760192:HALHY RS25540
gene id: 760192:HALHY_RS25540
uniprot id: F4L3E6
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS33095
gene id: 760192:HALHY_RS33095
uniprot id: F4L7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

760192:HALHY RS09980
gene id: 760192:HALHY_RS09980
uniprot id: F4L6M7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS32025
gene id: 760192:HALHY_RS32025
uniprot id: F4KQ53
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS10230
gene id: 760192:HALHY_RS10230
uniprot id: F4KPG5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS23830
gene id: 760192:HALHY_RS23830
uniprot id: F4KWV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

760192:HALHY RS17845
gene id: 760192:HALHY_RS17845
uniprot id: F4KXP6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

760192:HALHY RS15430
gene id: 760192:HALHY_RS15430
uniprot id: F4KPI8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

760192:HALHY RS28290
gene id: 760192:HALHY_RS28290
uniprot id: F4KUS6
names: Similarity
messages: Belongs to the ice-binding protein family.

760192:HALHY RS12185
gene id: 760192:HALHY_RS12185
uniprot id: F4KWE8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

760192:HALHY RS26705
gene id: 760192:HALHY_RS26705
uniprot id: F4L7D1
names: Similarity
messages: Belongs to the AHA1 family.

760192:HALHY RS18070
gene id: 760192:HALHY_RS18070
uniprot id: F4KYQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

760192:HALHY RS33145
gene id: 760192:HALHY_RS33145
uniprot id: F4L7T2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760192:HALHY RS17195
gene id: 760192:HALHY_RS17195
uniprot id: F4KVG2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

760192:HALHY RS22025
gene id: 760192:HALHY_RS22025
uniprot id: F4KQV2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

760192:HALHY RS17185
gene id: 760192:HALHY_RS17185
uniprot id: F4KVG0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

760192:HALHY RS01375
gene id: 760192:HALHY_RS01375
uniprot id: F4KVY6
names: Function
names: Similarity
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.

760192:HALHY RS17580
gene id: 760192:HALHY_RS17580
uniprot id: F4KWL3
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

760192:HALHY RS23845
gene id: 760192:HALHY_RS23845
uniprot id: F4KXT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

760192:HALHY RS13865
gene id: 760192:HALHY_RS13865
uniprot id: F4L1Z3
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS13340
gene id: 760192:HALHY_RS13340
uniprot id: F4KZT6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

760192:HALHY RS09880
gene id: 760192:HALHY_RS09880
uniprot id: F4L6L2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

760192:HALHY RS15605
gene id: 760192:HALHY_RS15605
uniprot id: F4KPM5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

760192:HALHY RS28585
gene id: 760192:HALHY_RS28585
uniprot id: F4KVW0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

760192:HALHY RS08470
gene id: 760192:HALHY_RS08470
uniprot id: F4L1R5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS22555
gene id: 760192:HALHY_RS22555
uniprot id: F4KTC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

760192:HALHY RS07780
gene id: 760192:HALHY_RS07780
uniprot id: F4KZH0
names: Similarity
messages: Belongs to the peptidase S33 family.

760192:HALHY RS06275
gene id: 760192:HALHY_RS06275
uniprot id: F4KU03
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS07315
gene id: 760192:HALHY_RS07315
uniprot id: F4KXE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

760192:HALHY RS34410
gene id: 760192:HALHY_RS34410
uniprot id: F4L1K7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS26240
gene id: 760192:HALHY_RS26240
uniprot id: F4L605
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

760192:HALHY RS23485
gene id: 760192:HALHY_RS23485
uniprot id: F4KVR4
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS11715
gene id: 760192:HALHY_RS11715
uniprot id: F4KV82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

760192:HALHY RS08790
gene id: 760192:HALHY_RS08790
uniprot id: F4L2W0
names: Subcellular Location Annotation
messages: Cytoplasm

760192:HALHY RS18635
gene id: 760192:HALHY_RS18635
uniprot id: F4KZZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

760192:HALHY RS15795
gene id: 760192:HALHY_RS15795
uniprot id: F4KQM8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

760192:HALHY RS26305
gene id: 760192:HALHY_RS26305
uniprot id: F4L618
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

760192:HALHY RS26985
gene id: 760192:HALHY_RS26985
uniprot id: F4KQ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

760192:HALHY RS07395
gene id: 760192:HALHY_RS07395
uniprot id: F4KYC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS24135
gene id: 760192:HALHY_RS24135
uniprot id: F4KXZ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

760192:HALHY RS31985
gene id: 760192:HALHY_RS31985
uniprot id: F4KQ45
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS23120
gene id: 760192:HALHY_RS23120
uniprot id: F4KUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

760192:HALHY RS07885
gene id: 760192:HALHY_RS07885
uniprot id: F4KZI9
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

760192:HALHY RS23255
gene id: 760192:HALHY_RS23255
uniprot id: F4KVL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

760192:HALHY RS12005
gene id: 760192:HALHY_RS12005
uniprot id: F4KWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

760192:HALHY RS25595
gene id: 760192:HALHY_RS25595
uniprot id: F4L3F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS14635
gene id: 760192:HALHY_RS14635
uniprot id: F4L476
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS01870
gene id: 760192:HALHY_RS01870
uniprot id: F4KX54
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS01740
gene id: 760192:HALHY_RS01740
uniprot id: F4KX28
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

760192:HALHY RS00435
gene id: 760192:HALHY_RS00435
uniprot id: F4KSN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

760192:HALHY RS17815
gene id: 760192:HALHY_RS17815
uniprot id: F4KXP0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS30460
gene id: 760192:HALHY_RS30460
uniprot id: F4L2J0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

760192:HALHY RS16630
gene id: 760192:HALHY_RS16630
uniprot id: F4KTB1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

760192:HALHY RS03490
gene id: 760192:HALHY_RS03490
uniprot id: F4L2P2
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS16640
gene id: 760192:HALHY_RS16640
uniprot id: F4KTB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

760192:HALHY RS16095
gene id: 760192:HALHY_RS16095
uniprot id: F4KRX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

760192:HALHY RS29020
gene id: 760192:HALHY_RS29020
uniprot id: F4KXZ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

760192:HALHY RS25305
gene id: 760192:HALHY_RS25305
uniprot id: F4L2C3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

760192:HALHY RS28905
gene id: 760192:HALHY_RS28905
uniprot id: F4KWZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS25675
gene id: 760192:HALHY_RS25675
uniprot id: F4L3H3
names: Similarity
messages: Belongs to the XseB family.

760192:HALHY RS03255
gene id: 760192:HALHY_RS03255
uniprot id: F4L1L5
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS04045
gene id: 760192:HALHY_RS04045
uniprot id: F4L3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

760192:HALHY RS07370
gene id: 760192:HALHY_RS07370
uniprot id: F4KXF2
names: Similarity
messages: Belongs to the LOG family.

760192:HALHY RS13520
gene id: 760192:HALHY_RS13520
uniprot id: F4L0V2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

760192:HALHY RS31525
gene id: 760192:HALHY_RS31525
uniprot id: F4L693
names: Similarity
messages: Belongs to the Nudix hydrolase family.

760192:HALHY RS08085
gene id: 760192:HALHY_RS08085
uniprot id: F4L0L7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

760192:HALHY RS04230
gene id: 760192:HALHY_RS04230
uniprot id: F4L527
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

760192:HALHY RS30380
gene id: 760192:HALHY_RS30380
uniprot id: F4L2H4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS31635
gene id: 760192:HALHY_RS31635
uniprot id: F4L7F3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

760192:HALHY RS10785
gene id: 760192:HALHY_RS10785
uniprot id: F4KRS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS32470
gene id: 760192:HALHY_RS32470
uniprot id: F4KRB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

760192:HALHY RS28120
gene id: 760192:HALHY_RS28120
uniprot id: F4KUP0
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS07145
gene id: 760192:HALHY_RS07145
uniprot id: F4KXA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

760192:HALHY RS11360
gene id: 760192:HALHY_RS11360
uniprot id: F4KU41
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

760192:HALHY RS16675
gene id: 760192:HALHY_RS16675
uniprot id: F4KTC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

760192:HALHY RS08240
gene id: 760192:HALHY_RS08240
uniprot id: F4L0P7
names: Similarity
messages: Belongs to the peptidase C56 family.

760192:HALHY RS05360
gene id: 760192:HALHY_RS05360
uniprot id: F4KQD5
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

760192:HALHY RS13160
gene id: 760192:HALHY_RS13160
uniprot id: F4KZP9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

760192:HALHY RS01650
gene id: 760192:HALHY_RS01650
uniprot id: F4KW40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760192:HALHY RS01085
gene id: 760192:HALHY_RS01085
uniprot id: F4KUV2
names: Similarity
messages: Belongs to the group II decarboxylase family.

760192:HALHY RS28875
gene id: 760192:HALHY_RS28875
uniprot id: F4KWZ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

760192:HALHY RS23810
gene id: 760192:HALHY_RS23810
uniprot id: F4KWV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

760192:HALHY RS17370
gene id: 760192:HALHY_RS17370
uniprot id: F4KVJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

760192:HALHY RS02965
gene id: 760192:HALHY_RS02965
uniprot id: F4L0J3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS10265
gene id: 760192:HALHY_RS10265
uniprot id: F4KPH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

760192:HALHY RS09000
gene id: 760192:HALHY_RS09000
uniprot id: F4L2Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

760192:HALHY RS27815
gene id: 760192:HALHY_RS27815
uniprot id: F4KTK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS31160
gene id: 760192:HALHY_RS31160
uniprot id: F4L4X9
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS05260
gene id: 760192:HALHY_RS05260
uniprot id: F4KQB7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS23900
gene id: 760192:HALHY_RS23900
uniprot id: F4KXU3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

760192:HALHY RS31815
gene id: 760192:HALHY_RS31815
uniprot id: F4L7J2
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

760192:HALHY RS14680
gene id: 760192:HALHY_RS14680
uniprot id: F4L485
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

760192:HALHY RS32080
gene id: 760192:HALHY_RS32080
uniprot id: F4KQ64
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS16100
gene id: 760192:HALHY_RS16100
uniprot id: F4KRX4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

760192:HALHY RS00335
gene id: 760192:HALHY_RS00335
uniprot id: F4KSL6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

760192:HALHY RS28165
gene id: 760192:HALHY_RS28165
uniprot id: F4KUP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

760192:HALHY RS32105
gene id: 760192:HALHY_RS32105
uniprot id: F4KQ69
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

760192:HALHY RS32455
gene id: 760192:HALHY_RS32455
uniprot id: F4KRB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

760192:HALHY RS09160
gene id: 760192:HALHY_RS09160
uniprot id: F4L3Z2
names: Similarity
messages: Belongs to the peptidase A31 family.

760192:HALHY RS31555
gene id: 760192:HALHY_RS31555
uniprot id: F4L699
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

760192:HALHY RS23865
gene id: 760192:HALHY_RS23865
uniprot id: F4KXT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

760192:HALHY RS20875
gene id: 760192:HALHY_RS20875
uniprot id: F4L4K9
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

760192:HALHY RS23370
gene id: 760192:HALHY_RS23370
uniprot id: F4KVP2
names: Similarity
messages: Belongs to the SusD family.

760192:HALHY RS22230
gene id: 760192:HALHY_RS22230
uniprot id: F4KQZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

760192:HALHY RS15975
gene id: 760192:HALHY_RS15975
uniprot id: F4KQR3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

760192:HALHY RS30440
gene id: 760192:HALHY_RS30440
uniprot id: F4L2I6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

760192:HALHY RS09725
gene id: 760192:HALHY_RS09725
uniprot id: F4L6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS19935
gene id: 760192:HALHY_RS19935
uniprot id: F4L4E9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

760192:HALHY RS31485
gene id: 760192:HALHY_RS31485
uniprot id: F4L686
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

760192:HALHY RS04240
gene id: 760192:HALHY_RS04240
uniprot id: F4L529
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

760192:HALHY RS23095
gene id: 760192:HALHY_RS23095
uniprot id: F4KUK6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS27730
gene id: 760192:HALHY_RS27730
uniprot id: F4KTJ1
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

760192:HALHY RS20390
gene id: 760192:HALHY_RS20390
uniprot id: F4L6V5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS25690
gene id: 760192:HALHY_RS25690
uniprot id: F4L3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

760192:HALHY RS09860
gene id: 760192:HALHY_RS09860
uniprot id: F4L6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

760192:HALHY RS23825
gene id: 760192:HALHY_RS23825
uniprot id: F4KWV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

760192:HALHY RS23270
gene id: 760192:HALHY_RS23270
uniprot id: F4KVM1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

760192:HALHY RS09470
gene id: 760192:HALHY_RS09470
uniprot id: F4L590
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

760192:HALHY RS17530
gene id: 760192:HALHY_RS17530
uniprot id: F4KWK3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760192:HALHY RS07995
gene id: 760192:HALHY_RS07995
uniprot id: F4KZL1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

760192:HALHY RS11060
gene id: 760192:HALHY_RS11060
uniprot id: F4KT11
names: Similarity
messages: Belongs to the FPG family.

760192:HALHY RS17705
gene id: 760192:HALHY_RS17705
uniprot id: F4KWN9
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS26940
gene id: 760192:HALHY_RS26940
uniprot id: F4KQ00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

760192:HALHY RS23850
gene id: 760192:HALHY_RS23850
uniprot id: F4KXT4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

760192:HALHY RS22400
gene id: 760192:HALHY_RS22400
uniprot id: F4KS64
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

760192:HALHY RS34510
gene id: 760192:HALHY_RS34510
uniprot id: F4KRN0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

760192:HALHY RS00950
gene id: 760192:HALHY_RS00950
uniprot id: F4KTV7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

760192:HALHY RS11900
gene id: 760192:HALHY_RS11900
uniprot id: F4KVB8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS01415
gene id: 760192:HALHY_RS01415
uniprot id: F4KVZ2
names: Similarity
messages: Belongs to the thioredoxin family.

760192:HALHY RS27725
gene id: 760192:HALHY_RS27725
uniprot id: F4KTJ0
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

760192:HALHY RS02330
gene id: 760192:HALHY_RS02330
uniprot id: F4KYA8
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS32665
gene id: 760192:HALHY_RS32665
uniprot id: F4KSJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS01370
gene id: 760192:HALHY_RS01370
uniprot id: F4KVY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

760192:HALHY RS11725
gene id: 760192:HALHY_RS11725
uniprot id: F4KV84
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS00140
gene id: 760192:HALHY_RS00140
uniprot id: F4KRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760192:HALHY RS32570
gene id: 760192:HALHY_RS32570
uniprot id: F4KSH1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

760192:HALHY RS01950
gene id: 760192:HALHY_RS01950
uniprot id: F4KX69
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

760192:HALHY RS13380
gene id: 760192:HALHY_RS13380
uniprot id: F4L0S6
names: Similarity
messages: Belongs to the peptidase S13 family.

760192:HALHY RS17555
gene id: 760192:HALHY_RS17555
uniprot id: F4KWK8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS06695
gene id: 760192:HALHY_RS06695
uniprot id: F4KV58
names: Similarity
messages: Belongs to the group II decarboxylase family.

760192:HALHY RS06430
gene id: 760192:HALHY_RS06430
uniprot id: F4KU34
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

760192:HALHY RS26930
gene id: 760192:HALHY_RS26930
uniprot id: F4KPZ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

760192:HALHY RS00600
gene id: 760192:HALHY_RS00600
uniprot id: F4KSR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

760192:HALHY RS23710
gene id: 760192:HALHY_RS23710
uniprot id: F4KWT2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

760192:HALHY RS25375
gene id: 760192:HALHY_RS25375
uniprot id: F4L2D7
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

760192:HALHY RS00190
gene id: 760192:HALHY_RS00190
uniprot id: F4KRG3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

760192:HALHY RS04050
gene id: 760192:HALHY_RS04050
uniprot id: F4L3V8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS01925
gene id: 760192:HALHY_RS01925
uniprot id: F4KX64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

760192:HALHY RS08180
gene id: 760192:HALHY_RS08180
uniprot id: F4L0N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS12675
gene id: 760192:HALHY_RS12675
uniprot id: F4KYI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

760192:HALHY RS05815
gene id: 760192:HALHY_RS05815
uniprot id: F4KSU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

760192:HALHY RS15995
gene id: 760192:HALHY_RS15995
uniprot id: F4KQR7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

760192:HALHY RS15645
gene id: 760192:HALHY_RS15645
uniprot id: F4KPN3
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

760192:HALHY RS02250
gene id: 760192:HALHY_RS02250
uniprot id: F4KY92
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

760192:HALHY RS21765
gene id: 760192:HALHY_RS21765
uniprot id: F4KPT5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

760192:HALHY RS23940
gene id: 760192:HALHY_RS23940
uniprot id: F4KXV1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

760192:HALHY RS33970
gene id: 760192:HALHY_RS33970
uniprot id: F4L8A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

760192:HALHY RS26850
gene id: 760192:HALHY_RS26850
uniprot id: F4KPY2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

760192:HALHY RS32950
gene id: 760192:HALHY_RS32950
uniprot id: F4L7N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MerT family.
messages: Cell inner membrane
messages: Membrane

760192:HALHY RS11160
gene id: 760192:HALHY_RS11160
uniprot id: F4KT31
names: Similarity
messages: Belongs to the Skp family.

760192:HALHY RS25930
gene id: 760192:HALHY_RS25930
uniprot id: F4L4Q4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

760192:HALHY RS17980
gene id: 760192:HALHY_RS17980
uniprot id: F4KXS2
names: Similarity
messages: Belongs to the CinA family.

760192:HALHY RS28200
gene id: 760192:HALHY_RS28200
uniprot id: F4KUQ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

760192:HALHY RS18505
gene id: 760192:HALHY_RS18505
uniprot id: F4KZW5
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS31615
gene id: 760192:HALHY_RS31615
uniprot id: F4L7E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

760192:HALHY RS05855
gene id: 760192:HALHY_RS05855
uniprot id: F4KSV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

760192:HALHY RS29320
gene id: 760192:HALHY_RS29320
uniprot id: F4KY57
names: Subcellular Location Annotation
messages: Membrane

760192:HALHY RS00845
gene id: 760192:HALHY_RS00845
uniprot id: F4KTT6
names: Similarity
messages: Belongs to the DEAD box helicase family.

760192:HALHY RS00960
gene id: 760192:HALHY_RS00960
uniprot id: F4KTV9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760192:HALHY RS02355
gene id: 760192:HALHY_RS02355
uniprot id: F4KYB3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

760192:HALHY RS15035
gene id: 760192:HALHY_RS15035
uniprot id: F4L5I9
names: Similarity
messages: Belongs to the serpin family.

760192:HALHY RS16360
gene id: 760192:HALHY_RS16360
uniprot id: F4KS27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

760192:HALHY RS02425
gene id: 760192:HALHY_RS02425
uniprot id: F4KZ95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

760192:HALHY RS17730
gene id: 760192:HALHY_RS17730
uniprot id: F4KXM3
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

760192:HALHY RS24300
gene id: 760192:HALHY_RS24300
uniprot id: F4KYZ4
names: Similarity
messages: Belongs to the glutamine synthetase family.

760192:HALHY RS22680
gene id: 760192:HALHY_RS22680
uniprot id: F4KTF2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane