760142:HIPMA RS02165
gene id: 760142:HIPMA_RS02165
uniprot id: F2LTZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

760142:HIPMA RS00850
gene id: 760142:HIPMA_RS00850
uniprot id: F2LX90
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS08870
gene id: 760142:HIPMA_RS08870
uniprot id: F2LUY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

760142:HIPMA RS07880
gene id: 760142:HIPMA_RS07880
uniprot id: F2LTV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

760142:HIPMA RS05555
gene id: 760142:HIPMA_RS05555
uniprot id: F2LWA8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

760142:HIPMA RS01505
gene id: 760142:HIPMA_RS01505
uniprot id: F2LY03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

760142:HIPMA RS00690
gene id: 760142:HIPMA_RS00690
uniprot id: F2LX61
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

760142:HIPMA RS04350
gene id: 760142:HIPMA_RS04350
uniprot id: F2LVN0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

760142:HIPMA RS08715
gene id: 760142:HIPMA_RS08715
uniprot id: F2LUP0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

760142:HIPMA RS01705
gene id: 760142:HIPMA_RS01705
uniprot id: F2LTI2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

760142:HIPMA RS02990
gene id: 760142:HIPMA_RS02990
uniprot id: F2LUU6
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS07940
gene id: 760142:HIPMA_RS07940
uniprot id: F2LTW4
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

760142:HIPMA RS07625
gene id: 760142:HIPMA_RS07625
uniprot id: F2LTQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

760142:HIPMA RS07505
gene id: 760142:HIPMA_RS07505
uniprot id: F2LY80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS01925
gene id: 760142:HIPMA_RS01925
uniprot id: F2LTM7
names: Similarity
messages: Belongs to the RutC family.

760142:HIPMA RS02200
gene id: 760142:HIPMA_RS02200
uniprot id: F2LTZ9
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS04195
gene id: 760142:HIPMA_RS04195
uniprot id: F2LVK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

760142:HIPMA RS01945
gene id: 760142:HIPMA_RS01945
uniprot id: F2LTN0
names: Similarity
messages: Belongs to the UPF0251 family.

760142:HIPMA RS03190
gene id: 760142:HIPMA_RS03190
uniprot id: F2LV05
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS00870
gene id: 760142:HIPMA_RS00870
uniprot id: F2LX94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

760142:HIPMA RS06120
gene id: 760142:HIPMA_RS06120
uniprot id: F2LWW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

760142:HIPMA RS04335
gene id: 760142:HIPMA_RS04335
uniprot id: F2LVM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

760142:HIPMA RS01500
gene id: 760142:HIPMA_RS01500
uniprot id: F2LY02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

760142:HIPMA RS01495
gene id: 760142:HIPMA_RS01495
uniprot id: F2LY01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS04840
gene id: 760142:HIPMA_RS04840
uniprot id: F2LVX3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

760142:HIPMA RS02860
gene id: 760142:HIPMA_RS02860
uniprot id: F2LUS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

760142:HIPMA RS00450
gene id: 760142:HIPMA_RS00450
uniprot id: F2LWU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

760142:HIPMA RS06845
gene id: 760142:HIPMA_RS06845
uniprot id: F2LXP2
names: Similarity
messages: Belongs to the HypE family.

760142:HIPMA RS04625
gene id: 760142:HIPMA_RS04625
uniprot id: F2LVT4
names: Similarity
messages: Belongs to the UPF0111 family.

760142:HIPMA RS06840
gene id: 760142:HIPMA_RS06840
uniprot id: F2LXP1
names: Similarity
messages: Belongs to the HypD family.

760142:HIPMA RS04375
gene id: 760142:HIPMA_RS04375
uniprot id: F2LVN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

760142:HIPMA RS06305
gene id: 760142:HIPMA_RS06305
uniprot id: F2LWZ8
names: Similarity
messages: Belongs to the UPF0235 family.

760142:HIPMA RS06810
gene id: 760142:HIPMA_RS06810
uniprot id: F2LXG2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

760142:HIPMA RS00365
gene id: 760142:HIPMA_RS00365
uniprot id: F2LWS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

760142:HIPMA RS06985
gene id: 760142:HIPMA_RS06985
uniprot id: F2LXR8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

760142:HIPMA RS09200
gene id: 760142:HIPMA_RS09200
uniprot id: F2LWM7
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

760142:HIPMA RS07000
gene id: 760142:HIPMA_RS07000
uniprot id: F2LXS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

760142:HIPMA RS05140
gene id: 760142:HIPMA_RS05140
uniprot id: F2LW29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

760142:HIPMA RS07325
gene id: 760142:HIPMA_RS07325
uniprot id: F2LY44
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

760142:HIPMA RS02810
gene id: 760142:HIPMA_RS02810
uniprot id: F2LUR2
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

760142:HIPMA RS05050
gene id: 760142:HIPMA_RS05050
uniprot id: F2LW11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

760142:HIPMA RS08070
gene id: 760142:HIPMA_RS08070
uniprot id: F2LU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

760142:HIPMA RS08240
gene id: 760142:HIPMA_RS08240
uniprot id: F2LTX1
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

760142:HIPMA RS04150
gene id: 760142:HIPMA_RS04150
uniprot id: F2LVJ4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

760142:HIPMA RS02400
gene id: 760142:HIPMA_RS02400
uniprot id: F2LUB0
names: Similarity
messages: Belongs to the sigma-54 factor family.

760142:HIPMA RS00370
gene id: 760142:HIPMA_RS00370
uniprot id: F2LWS8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

760142:HIPMA RS06575
gene id: 760142:HIPMA_RS06575
uniprot id: F2LXB7
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

760142:HIPMA RS00770
gene id: 760142:HIPMA_RS00770
uniprot id: F2LX76
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS07560
gene id: 760142:HIPMA_RS07560
uniprot id: F2LY90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

760142:HIPMA RS03980
gene id: 760142:HIPMA_RS03980
uniprot id: F2LVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

760142:HIPMA RS07330
gene id: 760142:HIPMA_RS07330
uniprot id: F2LY45
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

760142:HIPMA RS04775
gene id: 760142:HIPMA_RS04775
uniprot id: F2LVW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

760142:HIPMA RS02205
gene id: 760142:HIPMA_RS02205
uniprot id: F2LU00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS00235
gene id: 760142:HIPMA_RS00235
uniprot id: F2LWQ3
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS04405
gene id: 760142:HIPMA_RS04405
uniprot id: F2LVP1
names: Similarity
messages: Belongs to the UPF0751 family.

760142:HIPMA RS03685
gene id: 760142:HIPMA_RS03685
uniprot id: F2LVA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS06365
gene id: 760142:HIPMA_RS06365
uniprot id: F2LX10
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

760142:HIPMA RS00525
gene id: 760142:HIPMA_RS00525
uniprot id: F2LX30
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS04935
gene id: 760142:HIPMA_RS04935
uniprot id: F2LVZ2
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

760142:HIPMA RS07735
gene id: 760142:HIPMA_RS07735
uniprot id: F2LTS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

760142:HIPMA RS02345
gene id: 760142:HIPMA_RS02345
uniprot id: F2LU27
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

760142:HIPMA RS00315
gene id: 760142:HIPMA_RS00315
uniprot id: F2LTX0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

760142:HIPMA RS06610
gene id: 760142:HIPMA_RS06610
uniprot id: F2LXC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

760142:HIPMA RS08935
gene id: 760142:HIPMA_RS08935
uniprot id: F2LX29
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS08400
gene id: 760142:HIPMA_RS08400
uniprot id: F2LUI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

760142:HIPMA RS07800
gene id: 760142:HIPMA_RS07800
uniprot id: F2LTT6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS01740
gene id: 760142:HIPMA_RS01740
uniprot id: F2LTI9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

760142:HIPMA RS08100
gene id: 760142:HIPMA_RS08100
uniprot id: F2LU57
names: Similarity
messages: Belongs to the TrpF family.

760142:HIPMA RS02210
gene id: 760142:HIPMA_RS02210
uniprot id: F2LU01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS08650
gene id: 760142:HIPMA_RS08650
uniprot id: F2LUM8
names: Similarity
messages: Belongs to the peptidase M16 family.

760142:HIPMA RS03740
gene id: 760142:HIPMA_RS03740
uniprot id: F2LVB2
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS02125
gene id: 760142:HIPMA_RS02125
uniprot id: F2LTY4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS07060
gene id: 760142:HIPMA_RS07060
uniprot id: F2LXT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

760142:HIPMA RS02945
gene id: 760142:HIPMA_RS02945
uniprot id: F2LUT7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

760142:HIPMA RS02710
gene id: 760142:HIPMA_RS02710
uniprot id: F2LUH1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

760142:HIPMA RS04340
gene id: 760142:HIPMA_RS04340
uniprot id: F2LVM8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

760142:HIPMA RS06670
gene id: 760142:HIPMA_RS06670
uniprot id: F2LXD6
names: Similarity
messages: Belongs to the Skp family.

760142:HIPMA RS06960
gene id: 760142:HIPMA_RS06960
uniprot id: F2LXR3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

760142:HIPMA RS03955
gene id: 760142:HIPMA_RS03955
uniprot id: F2LVF5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

760142:HIPMA RS02350
gene id: 760142:HIPMA_RS02350
uniprot id: F2LU28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

760142:HIPMA RS05130
gene id: 760142:HIPMA_RS05130
uniprot id: F2LW27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

760142:HIPMA RS01725
gene id: 760142:HIPMA_RS01725
uniprot id: F2LTI6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

760142:HIPMA RS07455
gene id: 760142:HIPMA_RS07455
uniprot id: F2LY70
names: Similarity
messages: Belongs to the UPF0047 family.

760142:HIPMA RS01090
gene id: 760142:HIPMA_RS01090
uniprot id: F2LXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

760142:HIPMA RS04030
gene id: 760142:HIPMA_RS04030
uniprot id: F2LVH0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

760142:HIPMA RS04065
gene id: 760142:HIPMA_RS04065
uniprot id: F2LVH7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

760142:HIPMA RS08955
gene id: 760142:HIPMA_RS08955
uniprot id: F2LX81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

760142:HIPMA RS07420
gene id: 760142:HIPMA_RS07420
uniprot id: F2LY63
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

760142:HIPMA RS01450
gene id: 760142:HIPMA_RS01450
uniprot id: F2LXZ2
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS01555
gene id: 760142:HIPMA_RS01555
uniprot id: F2LY12
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

760142:HIPMA RS01250
gene id: 760142:HIPMA_RS01250
uniprot id: F2LXN8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

760142:HIPMA RS00955
gene id: 760142:HIPMA_RS00955
uniprot id: F2LXI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

760142:HIPMA RS05165
gene id: 760142:HIPMA_RS05165
uniprot id: F2LW34
names: Similarity
messages: Belongs to the ParB family.

760142:HIPMA RS00390
gene id: 760142:HIPMA_RS00390
uniprot id: F2LWT2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

760142:HIPMA RS03015
gene id: 760142:HIPMA_RS03015
uniprot id: F2LUV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

760142:HIPMA RS03940
gene id: 760142:HIPMA_RS03940
uniprot id: F2LVF2
names: Similarity
messages: Belongs to the peptidase M16 family.

760142:HIPMA RS07980
gene id: 760142:HIPMA_RS07980
uniprot id: F2LU35
names: Similarity
messages: Belongs to the UbiD family.

760142:HIPMA RS05520
gene id: 760142:HIPMA_RS05520
uniprot id: F2LWA1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

760142:HIPMA RS02305
gene id: 760142:HIPMA_RS02305
uniprot id: F2LU19
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

760142:HIPMA RS05090
gene id: 760142:HIPMA_RS05090
uniprot id: F2LW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

760142:HIPMA RS02560
gene id: 760142:HIPMA_RS02560
uniprot id: F2LUE1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

760142:HIPMA RS06260
gene id: 760142:HIPMA_RS06260
uniprot id: F2LWY9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

760142:HIPMA RS07080
gene id: 760142:HIPMA_RS07080
uniprot id: F2LXT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

760142:HIPMA RS00265
gene id: 760142:HIPMA_RS00265
uniprot id: F2LWR0
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

760142:HIPMA RS03105
gene id: 760142:HIPMA_RS03105
uniprot id: F2LUW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

760142:HIPMA RS00035
gene id: 760142:HIPMA_RS00035
uniprot id: F2LWE5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

760142:HIPMA RS03110
gene id: 760142:HIPMA_RS03110
uniprot id: F2LUW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

760142:HIPMA RS04970
gene id: 760142:HIPMA_RS04970
uniprot id: F2LTX0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

760142:HIPMA RS07830
gene id: 760142:HIPMA_RS07830
uniprot id: F2LTU2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

760142:HIPMA RS04585
gene id: 760142:HIPMA_RS04585
uniprot id: F2LVS6
names: Similarity
messages: Belongs to the PstS family.

760142:HIPMA RS01395
gene id: 760142:HIPMA_RS01395
uniprot id: F2LXY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

760142:HIPMA RS04135
gene id: 760142:HIPMA_RS04135
uniprot id: F2LVJ1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

760142:HIPMA RS07670
gene id: 760142:HIPMA_RS07670
uniprot id: F2LTR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

760142:HIPMA RS03710
gene id: 760142:HIPMA_RS03710
uniprot id: F2LVA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

760142:HIPMA RS02260
gene id: 760142:HIPMA_RS02260
uniprot id: F2LU10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS05180
gene id: 760142:HIPMA_RS05180
uniprot id: F2LW37
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

760142:HIPMA RS01220
gene id: 760142:HIPMA_RS01220
uniprot id: F2LXN2
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS05795
gene id: 760142:HIPMA_RS05795
uniprot id: F2LWH8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

760142:HIPMA RS06740
gene id: 760142:HIPMA_RS06740
uniprot id: F2LXF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS00025
gene id: 760142:HIPMA_RS00025
uniprot id: F2LWE3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

760142:HIPMA RS06910
gene id: 760142:HIPMA_RS06910
uniprot id: F2LXQ4
names: Similarity
messages: Belongs to the peptidase S49 family.

760142:HIPMA RS03165
gene id: 760142:HIPMA_RS03165
uniprot id: F2LV00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

760142:HIPMA RS07185
gene id: 760142:HIPMA_RS07185
uniprot id: F2LXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

760142:HIPMA RS00335
gene id: 760142:HIPMA_RS00335
uniprot id: F2LWS1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

760142:HIPMA RS07140
gene id: 760142:HIPMA_RS07140
uniprot id: F2LXU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

760142:HIPMA RS00790
gene id: 760142:HIPMA_RS00790
uniprot id: F2LX78
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

760142:HIPMA RS08450
gene id: 760142:HIPMA_RS08450
uniprot id: F2LUJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

760142:HIPMA RS01055
gene id: 760142:HIPMA_RS01055
uniprot id: F2LXJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

760142:HIPMA RS07395
gene id: 760142:HIPMA_RS07395
uniprot id: F2LY58
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760142:HIPMA RS05755
gene id: 760142:HIPMA_RS05755
uniprot id: F2LWH0
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

760142:HIPMA RS07100
gene id: 760142:HIPMA_RS07100
uniprot id: F2LXU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

760142:HIPMA RS08110
gene id: 760142:HIPMA_RS08110
uniprot id: F2LU59
names: Similarity
messages: Belongs to the TrpA family.

760142:HIPMA RS08315
gene id: 760142:HIPMA_RS08315
uniprot id: F2LU96
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

760142:HIPMA RS00600
gene id: 760142:HIPMA_RS00600
uniprot id: F2LX43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

760142:HIPMA RS06290
gene id: 760142:HIPMA_RS06290
uniprot id: F2LWZ5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

760142:HIPMA RS02785
gene id: 760142:HIPMA_RS02785
uniprot id: F2LUQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

760142:HIPMA RS05390
gene id: 760142:HIPMA_RS05390
uniprot id: F2LW79
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS01600
gene id: 760142:HIPMA_RS01600
uniprot id: F2LY21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

760142:HIPMA RS07105
gene id: 760142:HIPMA_RS07105
uniprot id: F2LXU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

760142:HIPMA RS00725
gene id: 760142:HIPMA_RS00725
uniprot id: F2LX68
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

760142:HIPMA RS00110
gene id: 760142:HIPMA_RS00110
uniprot id: F2LWG0
names: Similarity
messages: Belongs to the peptidase U62 family.

760142:HIPMA RS05650
gene id: 760142:HIPMA_RS05650
uniprot id: F2LWC5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

760142:HIPMA RS01400
gene id: 760142:HIPMA_RS01400
uniprot id: F2LXY2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

760142:HIPMA RS03935
gene id: 760142:HIPMA_RS03935
uniprot id: F2LVF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

760142:HIPMA RS07320
gene id: 760142:HIPMA_RS07320
uniprot id: F2LY43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

760142:HIPMA RS02565
gene id: 760142:HIPMA_RS02565
uniprot id: F2LUE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

760142:HIPMA RS04505
gene id: 760142:HIPMA_RS04505
uniprot id: F2LVR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

760142:HIPMA RS00705
gene id: 760142:HIPMA_RS00705
uniprot id: F2LX64
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

760142:HIPMA RS05160
gene id: 760142:HIPMA_RS05160
uniprot id: F2LW33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS02495
gene id: 760142:HIPMA_RS02495
uniprot id: F2LUC9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

760142:HIPMA RS02355
gene id: 760142:HIPMA_RS02355
uniprot id: F2LU29
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

760142:HIPMA RS00045
gene id: 760142:HIPMA_RS00045
uniprot id: F2LWE7
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

760142:HIPMA RS03455
gene id: 760142:HIPMA_RS03455
uniprot id: F2LV56
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

760142:HIPMA RS02130
gene id: 760142:HIPMA_RS02130
uniprot id: F2LTY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS01510
gene id: 760142:HIPMA_RS01510
uniprot id: F2LY04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

760142:HIPMA RS00900
gene id: 760142:HIPMA_RS00900
uniprot id: F2LXH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS01630
gene id: 760142:HIPMA_RS01630
uniprot id: F2LY27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

760142:HIPMA RS06160
gene id: 760142:HIPMA_RS06160
uniprot id: F2LWW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

760142:HIPMA RS03920
gene id: 760142:HIPMA_RS03920
uniprot id: F2LVE8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

760142:HIPMA RS01490
gene id: 760142:HIPMA_RS01490
uniprot id: F2LY00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

760142:HIPMA RS02695
gene id: 760142:HIPMA_RS02695
uniprot id: F2LUG8
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

760142:HIPMA RS06060
gene id: 760142:HIPMA_RS06060
uniprot id: F2LWM5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

760142:HIPMA RS07775
gene id: 760142:HIPMA_RS07775
uniprot id: F2LTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

760142:HIPMA RS01430
gene id: 760142:HIPMA_RS01430
uniprot id: F2LXY8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

760142:HIPMA RS06800
gene id: 760142:HIPMA_RS06800
uniprot id: F2LXG0
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS02680
gene id: 760142:HIPMA_RS02680
uniprot id: F2LUG5
names: Similarity
messages: Belongs to the acylphosphatase family.

760142:HIPMA RS01035
gene id: 760142:HIPMA_RS01035
uniprot id: F2LXJ4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

760142:HIPMA RS01980
gene id: 760142:HIPMA_RS01980
uniprot id: F2LTN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

760142:HIPMA RS00150
gene id: 760142:HIPMA_RS00150
uniprot id: F2LWN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

760142:HIPMA RS03645
gene id: 760142:HIPMA_RS03645
uniprot id: F2LV93
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

760142:HIPMA RS02365
gene id: 760142:HIPMA_RS02365
uniprot id: F2LU31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

760142:HIPMA RS00275
gene id: 760142:HIPMA_RS00275
uniprot id: F2LWR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

760142:HIPMA RS00385
gene id: 760142:HIPMA_RS00385
uniprot id: F2LWT1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

760142:HIPMA RS05735
gene id: 760142:HIPMA_RS05735
uniprot id: F2LWG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

760142:HIPMA RS02830
gene id: 760142:HIPMA_RS02830
uniprot id: F2LUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS05000
gene id: 760142:HIPMA_RS05000
uniprot id: F2LW01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

760142:HIPMA RS04540
gene id: 760142:HIPMA_RS04540
uniprot id: F2LVR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

760142:HIPMA RS08465
gene id: 760142:HIPMA_RS08465
uniprot id: F2LUJ6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

760142:HIPMA RS09045
gene id: 760142:HIPMA_RS09045
uniprot id: F2LU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

760142:HIPMA RS05335
gene id: 760142:HIPMA_RS05335
uniprot id: F2LW68
names: Similarity
messages: Belongs to the thioredoxin family.

760142:HIPMA RS05515
gene id: 760142:HIPMA_RS05515
uniprot id: F2LWA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

760142:HIPMA RS06680
gene id: 760142:HIPMA_RS06680
uniprot id: F2LXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

760142:HIPMA RS04370
gene id: 760142:HIPMA_RS04370
uniprot id: F2LVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

760142:HIPMA RS09000
gene id: 760142:HIPMA_RS09000
uniprot id: F2LY28
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

760142:HIPMA RS04220
gene id: 760142:HIPMA_RS04220
uniprot id: F2LVK8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

760142:HIPMA RS08890
gene id: 760142:HIPMA_RS08890
uniprot id: F2LUZ1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

760142:HIPMA RS04640
gene id: 760142:HIPMA_RS04640
uniprot id: F2LVT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

760142:HIPMA RS04055
gene id: 760142:HIPMA_RS04055
uniprot id: F2LVH5
names: Similarity
messages: Belongs to the AOR/FOR family.

760142:HIPMA RS03585
gene id: 760142:HIPMA_RS03585
uniprot id: F2LV82
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

760142:HIPMA RS02460
gene id: 760142:HIPMA_RS02460
uniprot id: F2LUC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

760142:HIPMA RS01230
gene id: 760142:HIPMA_RS01230
uniprot id: F2LXN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760142:HIPMA RS01765
gene id: 760142:HIPMA_RS01765
uniprot id: F2LTJ4
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS07225
gene id: 760142:HIPMA_RS07225
uniprot id: F2LXW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS07165
gene id: 760142:HIPMA_RS07165
uniprot id: F2LXV4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

760142:HIPMA RS03145
gene id: 760142:HIPMA_RS03145
uniprot id: F2LUZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

760142:HIPMA RS08685
gene id: 760142:HIPMA_RS08685
uniprot id: F2LUN5
names: Cofactor
messages: Binds 1 FAD per subunit.

760142:HIPMA RS04510
gene id: 760142:HIPMA_RS04510
uniprot id: F2LVR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

760142:HIPMA RS06705
gene id: 760142:HIPMA_RS06705
uniprot id: F2LXE3
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS05770
gene id: 760142:HIPMA_RS05770
uniprot id: F2LWH3
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

760142:HIPMA RS08280
gene id: 760142:HIPMA_RS08280
uniprot id: F2LU89
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

760142:HIPMA RS05365
gene id: 760142:HIPMA_RS05365
uniprot id: F2LW74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

760142:HIPMA RS02965
gene id: 760142:HIPMA_RS02965
uniprot id: F2LUU1
names: Similarity
messages: Belongs to the MotB family.

760142:HIPMA RS02295
gene id: 760142:HIPMA_RS02295
uniprot id: F2LU17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

760142:HIPMA RS06625
gene id: 760142:HIPMA_RS06625
uniprot id: F2LXC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

760142:HIPMA RS05150
gene id: 760142:HIPMA_RS05150
uniprot id: F2LW31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

760142:HIPMA RS07375
gene id: 760142:HIPMA_RS07375
uniprot id: F2LY54
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

760142:HIPMA RS05250
gene id: 760142:HIPMA_RS05250
uniprot id: F2LW51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

760142:HIPMA RS04965
gene id: 760142:HIPMA_RS04965
uniprot id: F2LTP3
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

760142:HIPMA RS01115
gene id: 760142:HIPMA_RS01115
uniprot id: F2LXL1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

760142:HIPMA RS07405
gene id: 760142:HIPMA_RS07405
uniprot id: F2LY60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

760142:HIPMA RS08405
gene id: 760142:HIPMA_RS08405
uniprot id: F2LUI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS01900
gene id: 760142:HIPMA_RS01900
uniprot id: F2LTM2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

760142:HIPMA RS04950
gene id: 760142:HIPMA_RS04950
uniprot id: F2LVZ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

760142:HIPMA RS01140
gene id: 760142:HIPMA_RS01140
uniprot id: F2LXL6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

760142:HIPMA RS07440
gene id: 760142:HIPMA_RS07440
uniprot id: F2LY67
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS04900
gene id: 760142:HIPMA_RS04900
uniprot id: F2LVY5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

760142:HIPMA RS04890
gene id: 760142:HIPMA_RS04890
uniprot id: F2LVY3
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

760142:HIPMA RS07610
gene id: 760142:HIPMA_RS07610
uniprot id: F2LTP8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

760142:HIPMA RS01065
gene id: 760142:HIPMA_RS01065
uniprot id: F2LXK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

760142:HIPMA RS04205
gene id: 760142:HIPMA_RS04205
uniprot id: F2LVK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

760142:HIPMA RS02505
gene id: 760142:HIPMA_RS02505
uniprot id: F2LUD1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

760142:HIPMA RS06350
gene id: 760142:HIPMA_RS06350
uniprot id: F2LX07
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

760142:HIPMA RS04230
gene id: 760142:HIPMA_RS04230
uniprot id: F2LVL0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

760142:HIPMA RS02370
gene id: 760142:HIPMA_RS02370
uniprot id: F2LU32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

760142:HIPMA RS07130
gene id: 760142:HIPMA_RS07130
uniprot id: F2LXU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

760142:HIPMA RS02450
gene id: 760142:HIPMA_RS02450
uniprot id: F2LUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

760142:HIPMA RS00995
gene id: 760142:HIPMA_RS00995
uniprot id: F2LTX0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

760142:HIPMA RS02340
gene id: 760142:HIPMA_RS02340
uniprot id: F2LU26
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

760142:HIPMA RS07665
gene id: 760142:HIPMA_RS07665
uniprot id: F2LTQ9
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS05255
gene id: 760142:HIPMA_RS05255
uniprot id: F2LW52
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

760142:HIPMA RS00430
gene id: 760142:HIPMA_RS00430
uniprot id: F2LWU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

760142:HIPMA RS08050
gene id: 760142:HIPMA_RS08050
uniprot id: F2LU48
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

760142:HIPMA RS04550
gene id: 760142:HIPMA_RS04550
uniprot id: F2LVR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

760142:HIPMA RS07015
gene id: 760142:HIPMA_RS07015
uniprot id: F2LXS4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

760142:HIPMA RS06115
gene id: 760142:HIPMA_RS06115
uniprot id: F2LWW1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS00510
gene id: 760142:HIPMA_RS00510
uniprot id: F2LX27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

760142:HIPMA RS07555
gene id: 760142:HIPMA_RS07555
uniprot id: F2LY89
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

760142:HIPMA RS08185
gene id: 760142:HIPMA_RS08185
uniprot id: F2LU72
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

760142:HIPMA RS04275
gene id: 760142:HIPMA_RS04275
uniprot id: F2LVL6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

760142:HIPMA RS04620
gene id: 760142:HIPMA_RS04620
uniprot id: F2LVT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

760142:HIPMA RS07365
gene id: 760142:HIPMA_RS07365
uniprot id: F2LY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

760142:HIPMA RS04780
gene id: 760142:HIPMA_RS04780
uniprot id: F2LVW1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

760142:HIPMA RS06570
gene id: 760142:HIPMA_RS06570
uniprot id: F2LXB6
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

760142:HIPMA RS04085
gene id: 760142:HIPMA_RS04085
uniprot id: F2LVI1
names: Subcellular Location Annotation
messages: Cytoplasm

760142:HIPMA RS05120
gene id: 760142:HIPMA_RS05120
uniprot id: F2LW25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

760142:HIPMA RS08885
gene id: 760142:HIPMA_RS08885
uniprot id: F2LUZ0
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS05395
gene id: 760142:HIPMA_RS05395
uniprot id: F2LW80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

760142:HIPMA RS07335
gene id: 760142:HIPMA_RS07335
uniprot id: F2LY46
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

760142:HIPMA RS05835
gene id: 760142:HIPMA_RS05835
uniprot id: F2LWI6
names: Similarity
messages: Belongs to the GSP E family.

760142:HIPMA RS01865
gene id: 760142:HIPMA_RS01865
uniprot id: F2LTL5
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

760142:HIPMA RS02465
gene id: 760142:HIPMA_RS02465
uniprot id: F2LUC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS01545
gene id: 760142:HIPMA_RS01545
uniprot id: F2LY10
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

760142:HIPMA RS07975
gene id: 760142:HIPMA_RS07975
uniprot id: F2LU34
names: Similarity
messages: Belongs to the ribF family.

760142:HIPMA RS01015
gene id: 760142:HIPMA_RS01015
uniprot id: F2LXJ0
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

760142:HIPMA RS09250
gene id: 760142:HIPMA_RS09250
uniprot id: F2LTR4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

760142:HIPMA RS02705
gene id: 760142:HIPMA_RS02705
uniprot id: F2LUH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

760142:HIPMA RS02655
gene id: 760142:HIPMA_RS02655
uniprot id: F2LUG0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

760142:HIPMA RS06470
gene id: 760142:HIPMA_RS06470
uniprot id: F2LX97
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

760142:HIPMA RS02170
gene id: 760142:HIPMA_RS02170
uniprot id: F2LTZ3
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

760142:HIPMA RS07435
gene id: 760142:HIPMA_RS07435
uniprot id: F2LY66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

760142:HIPMA RS08140
gene id: 760142:HIPMA_RS08140
uniprot id: F2LU65
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

760142:HIPMA RS04800
gene id: 760142:HIPMA_RS04800
uniprot id: F2LVW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

760142:HIPMA RS07890
gene id: 760142:HIPMA_RS07890
uniprot id: F2LTV4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS06110
gene id: 760142:HIPMA_RS06110
uniprot id: F2LWW0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

760142:HIPMA RS00065
gene id: 760142:HIPMA_RS00065
uniprot id: F2LWF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

760142:HIPMA RS05790
gene id: 760142:HIPMA_RS05790
uniprot id: F2LWH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS01605
gene id: 760142:HIPMA_RS01605
uniprot id: F2LY22
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

760142:HIPMA RS08625
gene id: 760142:HIPMA_RS08625
uniprot id: F2LUM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

760142:HIPMA RS00635
gene id: 760142:HIPMA_RS00635
uniprot id: F2LX50
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS02925
gene id: 760142:HIPMA_RS02925
uniprot id: F2LUT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

760142:HIPMA RS04675
gene id: 760142:HIPMA_RS04675
uniprot id: F2LVU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

760142:HIPMA RS08485
gene id: 760142:HIPMA_RS08485
uniprot id: F2LUK0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

760142:HIPMA RS02265
gene id: 760142:HIPMA_RS02265
uniprot id: F2LU11
names: Similarity
messages: Belongs to the peptidase M18 family.

760142:HIPMA RS01540
gene id: 760142:HIPMA_RS01540
uniprot id: F2LY09
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

760142:HIPMA RS02175
gene id: 760142:HIPMA_RS02175
uniprot id: F2LTZ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS04795
gene id: 760142:HIPMA_RS04795
uniprot id: F2LVW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

760142:HIPMA RS02225
gene id: 760142:HIPMA_RS02225
uniprot id: F2LU04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS07510
gene id: 760142:HIPMA_RS07510
uniprot id: F2LY81
names: Similarity
messages: Belongs to the TlyA family.

760142:HIPMA RS07220
gene id: 760142:HIPMA_RS07220
uniprot id: F2LXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

760142:HIPMA RS07125
gene id: 760142:HIPMA_RS07125
uniprot id: F2LXU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

760142:HIPMA RS02905
gene id: 760142:HIPMA_RS02905
uniprot id: F2LUT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

760142:HIPMA RS07180
gene id: 760142:HIPMA_RS07180
uniprot id: F2LXV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

760142:HIPMA RS01895
gene id: 760142:HIPMA_RS01895
uniprot id: F2LTM1
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

760142:HIPMA RS04355
gene id: 760142:HIPMA_RS04355
uniprot id: F2LVN1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS05490
gene id: 760142:HIPMA_RS05490
uniprot id: F2LW95
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

760142:HIPMA RS04025
gene id: 760142:HIPMA_RS04025
uniprot id: F2LVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

760142:HIPMA RS00695
gene id: 760142:HIPMA_RS00695
uniprot id: F2LX62
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

760142:HIPMA RS08200
gene id: 760142:HIPMA_RS08200
uniprot id: F2LU75
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

760142:HIPMA RS06825
gene id: 760142:HIPMA_RS06825
uniprot id: F2LXG5
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

760142:HIPMA RS06535
gene id: 760142:HIPMA_RS06535
uniprot id: F2LXA9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

760142:HIPMA RS05845
gene id: 760142:HIPMA_RS05845
uniprot id: F2LWI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

760142:HIPMA RS04320
gene id: 760142:HIPMA_RS04320
uniprot id: F2LVM5
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

760142:HIPMA RS07050
gene id: 760142:HIPMA_RS07050
uniprot id: F2LXT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

760142:HIPMA RS03650
gene id: 760142:HIPMA_RS03650
uniprot id: F2LV94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

760142:HIPMA RS03690
gene id: 760142:HIPMA_RS03690
uniprot id: F2LVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

760142:HIPMA RS00130
gene id: 760142:HIPMA_RS00130
uniprot id: F2LWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

760142:HIPMA RS05725
gene id: 760142:HIPMA_RS05725
uniprot id: F2LWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

760142:HIPMA RS06510
gene id: 760142:HIPMA_RS06510
uniprot id: F2LXA4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

760142:HIPMA RS00585
gene id: 760142:HIPMA_RS00585
uniprot id: F2LX40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

760142:HIPMA RS03055
gene id: 760142:HIPMA_RS03055
uniprot id: F2LUV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

760142:HIPMA RS01200
gene id: 760142:HIPMA_RS01200
uniprot id: F2LXM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

760142:HIPMA RS04120
gene id: 760142:HIPMA_RS04120
uniprot id: F2LVI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

760142:HIPMA RS07585
gene id: 760142:HIPMA_RS07585
uniprot id: F2LY95
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

760142:HIPMA RS04535
gene id: 760142:HIPMA_RS04535
uniprot id: F2LVR6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS02645
gene id: 760142:HIPMA_RS02645
uniprot id: F2LUF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

760142:HIPMA RS03625
gene id: 760142:HIPMA_RS03625
uniprot id: F2LV89
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

760142:HIPMA RS01270
gene id: 760142:HIPMA_RS01270
uniprot id: F2LXW3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

760142:HIPMA RS07085
gene id: 760142:HIPMA_RS07085
uniprot id: F2LXT8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

760142:HIPMA RS07730
gene id: 760142:HIPMA_RS07730
uniprot id: F2LTS2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS06890
gene id: 760142:HIPMA_RS06890
uniprot id: F2LXQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

760142:HIPMA RS04060
gene id: 760142:HIPMA_RS04060
uniprot id: F2LVH6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

760142:HIPMA RS08170
gene id: 760142:HIPMA_RS08170
uniprot id: F2LU69
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

760142:HIPMA RS08575
gene id: 760142:HIPMA_RS08575
uniprot id: F2LTX1
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

760142:HIPMA RS08045
gene id: 760142:HIPMA_RS08045
uniprot id: F2LU47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

760142:HIPMA RS08995
gene id: 760142:HIPMA_RS08995
uniprot id: F2LY25
names: Similarity
messages: Belongs to the transglycosylase Slt family.

760142:HIPMA RS00440
gene id: 760142:HIPMA_RS00440
uniprot id: F2LWU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

760142:HIPMA RS00075
gene id: 760142:HIPMA_RS00075
uniprot id: F2LWF3
names: Similarity
messages: Belongs to the peptidase S41A family.

760142:HIPMA RS07055
gene id: 760142:HIPMA_RS07055
uniprot id: F2LXT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

760142:HIPMA RS02955
gene id: 760142:HIPMA_RS02955
uniprot id: F2LUT9
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

760142:HIPMA RS07305
gene id: 760142:HIPMA_RS07305
uniprot id: F2LY40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

760142:HIPMA RS06400
gene id: 760142:HIPMA_RS06400
uniprot id: F2LX17
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS09060
gene id: 760142:HIPMA_RS09060
uniprot id: F2LUH2
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS02120
gene id: 760142:HIPMA_RS02120
uniprot id: F2LTY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

760142:HIPMA RS01190
gene id: 760142:HIPMA_RS01190
uniprot id: F2LXM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760142:HIPMA RS00840
gene id: 760142:HIPMA_RS00840
uniprot id: F2LX88
names: Similarity
messages: Belongs to the NadC/ModD family.

760142:HIPMA RS07145
gene id: 760142:HIPMA_RS07145
uniprot id: F2LXV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

760142:HIPMA RS02865
gene id: 760142:HIPMA_RS02865
uniprot id: F2LUS3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

760142:HIPMA RS05450
gene id: 760142:HIPMA_RS05450
uniprot id: F2LW87
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

760142:HIPMA RS07835
gene id: 760142:HIPMA_RS07835
uniprot id: F2LTU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

760142:HIPMA RS04000
gene id: 760142:HIPMA_RS04000
uniprot id: F2LVG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

760142:HIPMA RS08555
gene id: 760142:HIPMA_RS08555
uniprot id: F2LUL4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

760142:HIPMA RS04395
gene id: 760142:HIPMA_RS04395
uniprot id: F2LVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

760142:HIPMA RS02690
gene id: 760142:HIPMA_RS02690
uniprot id: F2LUG7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

760142:HIPMA RS00165
gene id: 760142:HIPMA_RS00165
uniprot id: F2LWN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

760142:HIPMA RS00640
gene id: 760142:HIPMA_RS00640
uniprot id: F2LX51
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS05480
gene id: 760142:HIPMA_RS05480
uniprot id: F2LW93
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS00665
gene id: 760142:HIPMA_RS00665
uniprot id: F2LX56
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

760142:HIPMA RS03630
gene id: 760142:HIPMA_RS03630
uniprot id: F2LV90
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

760142:HIPMA RS04010
gene id: 760142:HIPMA_RS04010
uniprot id: F2LVG6
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

760142:HIPMA RS07475
gene id: 760142:HIPMA_RS07475
uniprot id: F2LY74
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

760142:HIPMA RS06285
gene id: 760142:HIPMA_RS06285
uniprot id: F2LWZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

760142:HIPMA RS08230
gene id: 760142:HIPMA_RS08230
uniprot id: F2LTX0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

760142:HIPMA RS04770
gene id: 760142:HIPMA_RS04770
uniprot id: F2LVV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

760142:HIPMA RS07490
gene id: 760142:HIPMA_RS07490
uniprot id: F2LY77
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS06180
gene id: 760142:HIPMA_RS06180
uniprot id: F2LWX3
names: Similarity
messages: Belongs to the leucine-binding protein family.

760142:HIPMA RS07070
gene id: 760142:HIPMA_RS07070
uniprot id: F2LXT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

760142:HIPMA RS02670
gene id: 760142:HIPMA_RS02670
uniprot id: F2LUG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

760142:HIPMA RS02985
gene id: 760142:HIPMA_RS02985
uniprot id: F2LUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

760142:HIPMA RS09180
gene id: 760142:HIPMA_RS09180
uniprot id: F2LWC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

760142:HIPMA RS05605
gene id: 760142:HIPMA_RS05605
uniprot id: F2LWB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

760142:HIPMA RS01595
gene id: 760142:HIPMA_RS01595
uniprot id: F2LY20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

760142:HIPMA RS07950
gene id: 760142:HIPMA_RS07950
uniprot id: F2LTW6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

760142:HIPMA RS02215
gene id: 760142:HIPMA_RS02215
uniprot id: F2LU02
names: Similarity
messages: Belongs to the P(II) protein family.

760142:HIPMA RS07470
gene id: 760142:HIPMA_RS07470
uniprot id: F2LY73
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

760142:HIPMA RS01480
gene id: 760142:HIPMA_RS01480
uniprot id: F2LXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

760142:HIPMA RS08270
gene id: 760142:HIPMA_RS08270
uniprot id: F2LU87
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

760142:HIPMA RS03120
gene id: 760142:HIPMA_RS03120
uniprot id: F2LUX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

760142:HIPMA RS02625
gene id: 760142:HIPMA_RS02625
uniprot id: F2LUF4
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS05280
gene id: 760142:HIPMA_RS05280
uniprot id: F2LW57
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

760142:HIPMA RS05320
gene id: 760142:HIPMA_RS05320
uniprot id: F2LW65
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

760142:HIPMA RS02790
gene id: 760142:HIPMA_RS02790
uniprot id: F2LUQ8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

760142:HIPMA RS03750
gene id: 760142:HIPMA_RS03750
uniprot id: F2LVB4
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

760142:HIPMA RS00085
gene id: 760142:HIPMA_RS00085
uniprot id: F2LWF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

760142:HIPMA RS07945
gene id: 760142:HIPMA_RS07945
uniprot id: F2LTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS03140
gene id: 760142:HIPMA_RS03140
uniprot id: F2LUZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

760142:HIPMA RS08480
gene id: 760142:HIPMA_RS08480
uniprot id: F2LUJ9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

760142:HIPMA RS02455
gene id: 760142:HIPMA_RS02455
uniprot id: F2LUC1
names: Similarity
messages: Belongs to the GSP E family.

760142:HIPMA RS06990
gene id: 760142:HIPMA_RS06990
uniprot id: F2LXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

760142:HIPMA RS04475
gene id: 760142:HIPMA_RS04475
uniprot id: F2LVQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

760142:HIPMA RS08065
gene id: 760142:HIPMA_RS08065
uniprot id: F2LU51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

760142:HIPMA RS05245
gene id: 760142:HIPMA_RS05245
uniprot id: F2LW50
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

760142:HIPMA RS05975
gene id: 760142:HIPMA_RS05975
uniprot id: F2LTX0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

760142:HIPMA RS07400
gene id: 760142:HIPMA_RS07400
uniprot id: F2LY59
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

760142:HIPMA RS00005
gene id: 760142:HIPMA_RS00005
uniprot id: F2LWD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

760142:HIPMA RS04380
gene id: 760142:HIPMA_RS04380
uniprot id: F2LVN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

760142:HIPMA RS03210
gene id: 760142:HIPMA_RS03210
uniprot id: F2LV09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

760142:HIPMA RS05785
gene id: 760142:HIPMA_RS05785
uniprot id: F2LWH6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

760142:HIPMA RS08695
gene id: 760142:HIPMA_RS08695
uniprot id: F2LUN7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

760142:HIPMA RS02815
gene id: 760142:HIPMA_RS02815
uniprot id: F2LUR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

760142:HIPMA RS01265
gene id: 760142:HIPMA_RS01265
uniprot id: F2LXW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

760142:HIPMA RS00040
gene id: 760142:HIPMA_RS00040
uniprot id: F2LWE6
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

760142:HIPMA RS02660
gene id: 760142:HIPMA_RS02660
uniprot id: F2LUG1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

760142:HIPMA RS02745
gene id: 760142:HIPMA_RS02745
uniprot id: F2LUH8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

760142:HIPMA RS01380
gene id: 760142:HIPMA_RS01380
uniprot id: F2LXX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

760142:HIPMA RS01130
gene id: 760142:HIPMA_RS01130
uniprot id: F2LXL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS03745
gene id: 760142:HIPMA_RS03745
uniprot id: F2LVB3
names: Subcellular Location Annotation
messages: Periplasm

760142:HIPMA RS05045
gene id: 760142:HIPMA_RS05045
uniprot id: F2LW10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

760142:HIPMA RS05300
gene id: 760142:HIPMA_RS05300
uniprot id: F2LW61
names: Similarity
messages: Belongs to the UPF0173 family.

760142:HIPMA RS06370
gene id: 760142:HIPMA_RS06370
uniprot id: F2LX11
names: Similarity
messages: Belongs to the UPF0045 family.

760142:HIPMA RS07345
gene id: 760142:HIPMA_RS07345
uniprot id: F2LY48
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

760142:HIPMA RS04465
gene id: 760142:HIPMA_RS04465
uniprot id: F2LVQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS07075
gene id: 760142:HIPMA_RS07075
uniprot id: F2LXT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

760142:HIPMA RS02010
gene id: 760142:HIPMA_RS02010
uniprot id: F2LTP3
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

760142:HIPMA RS05110
gene id: 760142:HIPMA_RS05110
uniprot id: F2LW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

760142:HIPMA RS01070
gene id: 760142:HIPMA_RS01070
uniprot id: F2LXK2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

760142:HIPMA RS03160
gene id: 760142:HIPMA_RS03160
uniprot id: F2LUZ9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

760142:HIPMA RS02740
gene id: 760142:HIPMA_RS02740
uniprot id: F2LUH7
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS02410
gene id: 760142:HIPMA_RS02410
uniprot id: F2LUB2
names: Similarity
messages: Belongs to the RemA family.

760142:HIPMA RS06715
gene id: 760142:HIPMA_RS06715
uniprot id: F2LXE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

760142:HIPMA RS04980
gene id: 760142:HIPMA_RS04980
uniprot id: F2LTX1
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

760142:HIPMA RS04160
gene id: 760142:HIPMA_RS04160
uniprot id: F2LVJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

760142:HIPMA RS00030
gene id: 760142:HIPMA_RS00030
uniprot id: F2LWE4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

760142:HIPMA RS06655
gene id: 760142:HIPMA_RS06655
uniprot id: F2LXD3
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS01890
gene id: 760142:HIPMA_RS01890
uniprot id: F2LTM0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

760142:HIPMA RS01850
gene id: 760142:HIPMA_RS01850
uniprot id: F2LTL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

760142:HIPMA RS02415
gene id: 760142:HIPMA_RS02415
uniprot id: F2LUB3
names: Similarity
messages: Belongs to the guanylate kinase family.

760142:HIPMA RS00445
gene id: 760142:HIPMA_RS00445
uniprot id: F2LWU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

760142:HIPMA RS08295
gene id: 760142:HIPMA_RS08295
uniprot id: F2LU92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

760142:HIPMA RS07160
gene id: 760142:HIPMA_RS07160
uniprot id: F2LXV3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

760142:HIPMA RS03695
gene id: 760142:HIPMA_RS03695
uniprot id: F2LVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

760142:HIPMA RS01845
gene id: 760142:HIPMA_RS01845
uniprot id: F2LTL1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

760142:HIPMA RS04235
gene id: 760142:HIPMA_RS04235
uniprot id: F2LVL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

760142:HIPMA RS01435
gene id: 760142:HIPMA_RS01435
uniprot id: F2LXY9
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS07990
gene id: 760142:HIPMA_RS07990
uniprot id: F2LU37
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

760142:HIPMA RS00890
gene id: 760142:HIPMA_RS00890
uniprot id: F2LXH0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

760142:HIPMA RS00155
gene id: 760142:HIPMA_RS00155
uniprot id: F2LWN7
names: Similarity
messages: Belongs to the aspartokinase family.

760142:HIPMA RS07815
gene id: 760142:HIPMA_RS07815
uniprot id: F2LTT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

760142:HIPMA RS07095
gene id: 760142:HIPMA_RS07095
uniprot id: F2LXU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

760142:HIPMA RS08030
gene id: 760142:HIPMA_RS08030
uniprot id: F2LU44
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

760142:HIPMA RS01615
gene id: 760142:HIPMA_RS01615
uniprot id: F2LY24
names: Similarity
messages: Belongs to the FlgM family.

760142:HIPMA RS02005
gene id: 760142:HIPMA_RS02005
uniprot id: F2LTM2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

760142:HIPMA RS06995
gene id: 760142:HIPMA_RS06995
uniprot id: F2LXS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

760142:HIPMA RS06815
gene id: 760142:HIPMA_RS06815
uniprot id: F2LXG3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

760142:HIPMA RS08120
gene id: 760142:HIPMA_RS08120
uniprot id: F2LU61
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

760142:HIPMA RS07115
gene id: 760142:HIPMA_RS07115
uniprot id: F2LXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

760142:HIPMA RS03590
gene id: 760142:HIPMA_RS03590
uniprot id: F2LV83
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

760142:HIPMA RS04175
gene id: 760142:HIPMA_RS04175
uniprot id: F2LVJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

760142:HIPMA RS05025
gene id: 760142:HIPMA_RS05025
uniprot id: F2LW06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

760142:HIPMA RS06595
gene id: 760142:HIPMA_RS06595
uniprot id: F2LXC1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

760142:HIPMA RS05760
gene id: 760142:HIPMA_RS05760
uniprot id: F2LWH1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

760142:HIPMA RS02760
gene id: 760142:HIPMA_RS02760
uniprot id: F2LUQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

760142:HIPMA RS07655
gene id: 760142:HIPMA_RS07655
uniprot id: F2LTQ7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

760142:HIPMA RS06775
gene id: 760142:HIPMA_RS06775
uniprot id: F2LXF5
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS00885
gene id: 760142:HIPMA_RS00885
uniprot id: F2LXG9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

760142:HIPMA RS06955
gene id: 760142:HIPMA_RS06955
uniprot id: F2LXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

760142:HIPMA RS03350
gene id: 760142:HIPMA_RS03350
uniprot id: F2LV32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

760142:HIPMA RS00435
gene id: 760142:HIPMA_RS00435
uniprot id: F2LWU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS00425
gene id: 760142:HIPMA_RS00425
uniprot id: F2LWT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

760142:HIPMA RS02850
gene id: 760142:HIPMA_RS02850
uniprot id: F2LUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

760142:HIPMA RS00595
gene id: 760142:HIPMA_RS00595
uniprot id: F2LX42
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS04580
gene id: 760142:HIPMA_RS04580
uniprot id: F2LVS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

760142:HIPMA RS01675
gene id: 760142:HIPMA_RS01675
uniprot id: F2LTH6
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS06690
gene id: 760142:HIPMA_RS06690
uniprot id: F2LXE0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

760142:HIPMA RS05125
gene id: 760142:HIPMA_RS05125
uniprot id: F2LW26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

760142:HIPMA RS05020
gene id: 760142:HIPMA_RS05020
uniprot id: F2LW05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

760142:HIPMA RS01665
gene id: 760142:HIPMA_RS01665
uniprot id: F2LTH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

760142:HIPMA RS05415
gene id: 760142:HIPMA_RS05415
uniprot id: F2LW82
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

760142:HIPMA RS05065
gene id: 760142:HIPMA_RS05065
uniprot id: F2LW14
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

760142:HIPMA RS00880
gene id: 760142:HIPMA_RS00880
uniprot id: F2LXG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

760142:HIPMA RS06125
gene id: 760142:HIPMA_RS06125
uniprot id: F2LWW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

760142:HIPMA RS04440
gene id: 760142:HIPMA_RS04440
uniprot id: F2LVP7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

760142:HIPMA RS08840
gene id: 760142:HIPMA_RS08840
uniprot id: F2LTX0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

760142:HIPMA RS05175
gene id: 760142:HIPMA_RS05175
uniprot id: F2LW36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS05440
gene id: 760142:HIPMA_RS05440
uniprot id: F2LW85
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

760142:HIPMA RS00360
gene id: 760142:HIPMA_RS00360
uniprot id: F2LWS6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

760142:HIPMA RS06225
gene id: 760142:HIPMA_RS06225
uniprot id: F2LWY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

760142:HIPMA RS07725
gene id: 760142:HIPMA_RS07725
uniprot id: F2LTS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

760142:HIPMA RS07010
gene id: 760142:HIPMA_RS07010
uniprot id: F2LXS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

760142:HIPMA RS01060
gene id: 760142:HIPMA_RS01060
uniprot id: F2LXK0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

760142:HIPMA RS07090
gene id: 760142:HIPMA_RS07090
uniprot id: F2LXT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

760142:HIPMA RS07780
gene id: 760142:HIPMA_RS07780
uniprot id: F2LTT2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

760142:HIPMA RS08320
gene id: 760142:HIPMA_RS08320
uniprot id: F2LU97
names: Similarity
messages: Belongs to the CobH/CbiC family.

760142:HIPMA RS04110
gene id: 760142:HIPMA_RS04110
uniprot id: F2LVI6
names: Similarity
messages: Belongs to the peptidase S16 family.

760142:HIPMA RS02890
gene id: 760142:HIPMA_RS02890
uniprot id: F2LUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

760142:HIPMA RS08635
gene id: 760142:HIPMA_RS08635
uniprot id: F2LUM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

760142:HIPMA RS06015
gene id: 760142:HIPMA_RS06015
uniprot id: F2LWL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cytoplasm
messages: Monomer.

760142:HIPMA RS07120
gene id: 760142:HIPMA_RS07120
uniprot id: F2LXU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

760142:HIPMA RS02310
gene id: 760142:HIPMA_RS02310
uniprot id: F2LU20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

760142:HIPMA RS07410
gene id: 760142:HIPMA_RS07410
uniprot id: F2LY61
names: Similarity
messages: Belongs to the DEAD box helicase family.

760142:HIPMA RS00105
gene id: 760142:HIPMA_RS00105
uniprot id: F2LWF9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

760142:HIPMA RS04115
gene id: 760142:HIPMA_RS04115
uniprot id: F2LVI7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

760142:HIPMA RS01550
gene id: 760142:HIPMA_RS01550
uniprot id: F2LY11
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

760142:HIPMA RS03660
gene id: 760142:HIPMA_RS03660
uniprot id: F2LV96
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

760142:HIPMA RS02220
gene id: 760142:HIPMA_RS02220
uniprot id: F2LU03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS03205
gene id: 760142:HIPMA_RS03205
uniprot id: F2LV08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

760142:HIPMA RS02895
gene id: 760142:HIPMA_RS02895
uniprot id: F2LUS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

760142:HIPMA RS01285
gene id: 760142:HIPMA_RS01285
uniprot id: F2LXW6
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS04565
gene id: 760142:HIPMA_RS04565
uniprot id: F2LVS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

760142:HIPMA RS01205
gene id: 760142:HIPMA_RS01205
uniprot id: F2LXM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760142:HIPMA RS02390
gene id: 760142:HIPMA_RS02390
uniprot id: F2LUA8
names: Similarity
messages: Belongs to the pyruvate kinase family.

760142:HIPMA RS04725
gene id: 760142:HIPMA_RS04725
uniprot id: F2LVV1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

760142:HIPMA RS01005
gene id: 760142:HIPMA_RS01005
uniprot id: F2LXI8
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS01425
gene id: 760142:HIPMA_RS01425
uniprot id: F2LXY7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

760142:HIPMA RS01995
gene id: 760142:HIPMA_RS01995
uniprot id: F2LTP0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

760142:HIPMA RS00495
gene id: 760142:HIPMA_RS00495
uniprot id: F2LWV4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

760142:HIPMA RS08415
gene id: 760142:HIPMA_RS08415
uniprot id: F2LUI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

760142:HIPMA RS06390
gene id: 760142:HIPMA_RS06390
uniprot id: F2LX15
names: Similarity
messages: Belongs to the BMP lipoprotein family.

760142:HIPMA RS06355
gene id: 760142:HIPMA_RS06355
uniprot id: F2LX08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

760142:HIPMA RS08060
gene id: 760142:HIPMA_RS08060
uniprot id: F2LU50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS02960
gene id: 760142:HIPMA_RS02960
uniprot id: F2LUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Cell inner membrane
messages: Membrane

760142:HIPMA RS05745
gene id: 760142:HIPMA_RS05745
uniprot id: F2LWG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

760142:HIPMA RS06215
gene id: 760142:HIPMA_RS06215
uniprot id: F2LWY0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

760142:HIPMA RS07170
gene id: 760142:HIPMA_RS07170
uniprot id: F2LXV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

760142:HIPMA RS07135
gene id: 760142:HIPMA_RS07135
uniprot id: F2LXU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

760142:HIPMA RS06700
gene id: 760142:HIPMA_RS06700
uniprot id: F2LXE2
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

760142:HIPMA RS07035
gene id: 760142:HIPMA_RS07035
uniprot id: F2LXS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

760142:HIPMA RS01210
gene id: 760142:HIPMA_RS01210
uniprot id: F2LXN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760142:HIPMA RS05585
gene id: 760142:HIPMA_RS05585
uniprot id: F2LWB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

760142:HIPMA RS00505
gene id: 760142:HIPMA_RS00505
uniprot id: F2LX26
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

760142:HIPMA RS05510
gene id: 760142:HIPMA_RS05510
uniprot id: F2LW99
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

760142:HIPMA RS01965
gene id: 760142:HIPMA_RS01965
uniprot id: F2LTN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

760142:HIPMA RS00590
gene id: 760142:HIPMA_RS00590
uniprot id: F2LX41
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS00675
gene id: 760142:HIPMA_RS00675
uniprot id: F2LX58
names: Similarity
messages: Belongs to the class-I fumarase family.

760142:HIPMA RS01235
gene id: 760142:HIPMA_RS01235
uniprot id: F2LXN5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

760142:HIPMA RS05465
gene id: 760142:HIPMA_RS05465
uniprot id: F2LW90
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

760142:HIPMA RS01300
gene id: 760142:HIPMA_RS01300
uniprot id: F2LXW9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

760142:HIPMA RS00655
gene id: 760142:HIPMA_RS00655
uniprot id: F2LX54
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

760142:HIPMA RS07970
gene id: 760142:HIPMA_RS07970
uniprot id: F2LU33
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

760142:HIPMA RS08655
gene id: 760142:HIPMA_RS08655
uniprot id: F2LUM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

760142:HIPMA RS08105
gene id: 760142:HIPMA_RS08105
uniprot id: F2LU58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

760142:HIPMA RS02180
gene id: 760142:HIPMA_RS02180
uniprot id: F2LTZ5
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS00490
gene id: 760142:HIPMA_RS00490
uniprot id: F2LWV3
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS02405
gene id: 760142:HIPMA_RS02405
uniprot id: F2LUB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

760142:HIPMA RS02755
gene id: 760142:HIPMA_RS02755
uniprot id: F2LUQ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

760142:HIPMA RS04815
gene id: 760142:HIPMA_RS04815
uniprot id: F2LVW8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

760142:HIPMA RS03875
gene id: 760142:HIPMA_RS03875
uniprot id: F2LVD9
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

760142:HIPMA RS02385
gene id: 760142:HIPMA_RS02385
uniprot id: F2LUA7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

760142:HIPMA RS01645
gene id: 760142:HIPMA_RS01645
uniprot id: F2LTH0
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS00195
gene id: 760142:HIPMA_RS00195
uniprot id: F2LWP5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

760142:HIPMA RS06105
gene id: 760142:HIPMA_RS06105
uniprot id: F2LWV9
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

760142:HIPMA RS06240
gene id: 760142:HIPMA_RS06240
uniprot id: F2LWY5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

760142:HIPMA RS06280
gene id: 760142:HIPMA_RS06280
uniprot id: F2LWZ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

760142:HIPMA RS07875
gene id: 760142:HIPMA_RS07875
uniprot id: F2LTV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

760142:HIPMA RS05080
gene id: 760142:HIPMA_RS05080
uniprot id: F2LW17
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

760142:HIPMA RS03970
gene id: 760142:HIPMA_RS03970
uniprot id: F2LVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

760142:HIPMA RS04695
gene id: 760142:HIPMA_RS04695
uniprot id: F2LVU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

760142:HIPMA RS08145
gene id: 760142:HIPMA_RS08145
uniprot id: F2LU66
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

760142:HIPMA RS00535
gene id: 760142:HIPMA_RS00535
uniprot id: F2LX32
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

760142:HIPMA RS02510
gene id: 760142:HIPMA_RS02510
uniprot id: F2LUD2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

760142:HIPMA RS05370
gene id: 760142:HIPMA_RS05370
uniprot id: F2LW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

760142:HIPMA RS05935
gene id: 760142:HIPMA_RS05935
uniprot id: F2LWK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

760142:HIPMA RS01795
gene id: 760142:HIPMA_RS01795
uniprot id: F2LTK0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

760142:HIPMA RS05730
gene id: 760142:HIPMA_RS05730
uniprot id: F2LWG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS08090
gene id: 760142:HIPMA_RS08090
uniprot id: F2LU55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS01305
gene id: 760142:HIPMA_RS01305
uniprot id: F2LXX0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

760142:HIPMA RS04930
gene id: 760142:HIPMA_RS04930
uniprot id: F2LVZ1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

760142:HIPMA RS02330
gene id: 760142:HIPMA_RS02330
uniprot id: F2LU24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

760142:HIPMA RS06980
gene id: 760142:HIPMA_RS06980
uniprot id: F2LXR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

760142:HIPMA RS08430
gene id: 760142:HIPMA_RS08430
uniprot id: F2LUI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

760142:HIPMA RS00700
gene id: 760142:HIPMA_RS00700
uniprot id: F2LX63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

760142:HIPMA RS04910
gene id: 760142:HIPMA_RS04910
uniprot id: F2LVY7
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

760142:HIPMA RS06710
gene id: 760142:HIPMA_RS06710
uniprot id: F2LXE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

760142:HIPMA RS05070
gene id: 760142:HIPMA_RS05070
uniprot id: F2LW15
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

760142:HIPMA RS02970
gene id: 760142:HIPMA_RS02970
uniprot id: F2LUU2
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS00650
gene id: 760142:HIPMA_RS00650
uniprot id: F2LX53
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

760142:HIPMA RS07255
gene id: 760142:HIPMA_RS07255
uniprot id: F2LY30
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

760142:HIPMA RS07350
gene id: 760142:HIPMA_RS07350
uniprot id: F2LY49
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

760142:HIPMA RS00795
gene id: 760142:HIPMA_RS00795
uniprot id: F2LX79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

760142:HIPMA RS04665
gene id: 760142:HIPMA_RS04665
uniprot id: F2LVU1
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS07500
gene id: 760142:HIPMA_RS07500
uniprot id: F2LY79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS00745
gene id: 760142:HIPMA_RS00745
uniprot id: F2LX71
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS06835
gene id: 760142:HIPMA_RS06835
uniprot id: F2LXG7
names: Similarity
messages: Belongs to the HupF/HypC family.

760142:HIPMA RS01135
gene id: 760142:HIPMA_RS01135
uniprot id: F2LXL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

760142:HIPMA RS01150
gene id: 760142:HIPMA_RS01150
uniprot id: F2LXL8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS04575
gene id: 760142:HIPMA_RS04575
uniprot id: F2LVS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS06045
gene id: 760142:HIPMA_RS06045
uniprot id: F2LWM2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

760142:HIPMA RS02425
gene id: 760142:HIPMA_RS02425
uniprot id: F2LUB5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

760142:HIPMA RS01775
gene id: 760142:HIPMA_RS01775
uniprot id: F2LTJ6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS07025
gene id: 760142:HIPMA_RS07025
uniprot id: F2LXS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

760142:HIPMA RS02015
gene id: 760142:HIPMA_RS02015
uniprot id: F2LTX0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

760142:HIPMA RS04345
gene id: 760142:HIPMA_RS04345
uniprot id: F2LVM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

760142:HIPMA RS03720
gene id: 760142:HIPMA_RS03720
uniprot id: F2LVA8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

760142:HIPMA RS08800
gene id: 760142:HIPMA_RS08800
uniprot id: F2LUX6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

760142:HIPMA RS08810
gene id: 760142:HIPMA_RS08810
uniprot id: F2LUX8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

760142:HIPMA RS03090
gene id: 760142:HIPMA_RS03090
uniprot id: F2LUW4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

760142:HIPMA RS07150
gene id: 760142:HIPMA_RS07150
uniprot id: F2LXV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

760142:HIPMA RS05340
gene id: 760142:HIPMA_RS05340
uniprot id: F2LW69
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

760142:HIPMA RS07965
gene id: 760142:HIPMA_RS07965
uniprot id: F2LTW9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

760142:HIPMA RS06220
gene id: 760142:HIPMA_RS06220
uniprot id: F2LWY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

760142:HIPMA RS08725
gene id: 760142:HIPMA_RS08725
uniprot id: F2LTX1
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

760142:HIPMA RS07870
gene id: 760142:HIPMA_RS07870
uniprot id: F2LTV0
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS06010
gene id: 760142:HIPMA_RS06010
uniprot id: F2LWL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

760142:HIPMA RS07415
gene id: 760142:HIPMA_RS07415
uniprot id: F2LY62
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS01030
gene id: 760142:HIPMA_RS01030
uniprot id: F2LXJ3
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

760142:HIPMA RS03480
gene id: 760142:HIPMA_RS03480
uniprot id: F2LV61
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

760142:HIPMA RS08820
gene id: 760142:HIPMA_RS08820
uniprot id: F2LUY0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

760142:HIPMA RS02420
gene id: 760142:HIPMA_RS02420
uniprot id: F2LUB4
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

760142:HIPMA RS06205
gene id: 760142:HIPMA_RS06205
uniprot id: F2LWX8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

760142:HIPMA RS03010
gene id: 760142:HIPMA_RS03010
uniprot id: F2LUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

760142:HIPMA RS05655
gene id: 760142:HIPMA_RS05655
uniprot id: F2LWC6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

760142:HIPMA RS00915
gene id: 760142:HIPMA_RS00915
uniprot id: F2LXH5
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS08660
gene id: 760142:HIPMA_RS08660
uniprot id: F2LUN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

760142:HIPMA RS05235
gene id: 760142:HIPMA_RS05235
uniprot id: F2LW48
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

760142:HIPMA RS04915
gene id: 760142:HIPMA_RS04915
uniprot id: F2LVY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

760142:HIPMA RS07065
gene id: 760142:HIPMA_RS07065
uniprot id: F2LXT4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

760142:HIPMA RS03905
gene id: 760142:HIPMA_RS03905
uniprot id: F2LVE5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

760142:HIPMA RS03150
gene id: 760142:HIPMA_RS03150
uniprot id: F2LUZ7
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS06965
gene id: 760142:HIPMA_RS06965
uniprot id: F2LXR4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

760142:HIPMA RS08665
gene id: 760142:HIPMA_RS08665
uniprot id: F2LUN1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS06685
gene id: 760142:HIPMA_RS06685
uniprot id: F2LXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

760142:HIPMA RS01215
gene id: 760142:HIPMA_RS01215
uniprot id: F2LXN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760142:HIPMA RS06050
gene id: 760142:HIPMA_RS06050
uniprot id: F2LWM3
names: Similarity
messages: Belongs to the GPI family.

760142:HIPMA RS08175
gene id: 760142:HIPMA_RS08175
uniprot id: F2LU70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Homodimer.

760142:HIPMA RS06385
gene id: 760142:HIPMA_RS06385
uniprot id: F2LX14
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

760142:HIPMA RS01700
gene id: 760142:HIPMA_RS01700
uniprot id: F2LTI1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

760142:HIPMA RS07270
gene id: 760142:HIPMA_RS07270
uniprot id: F2LY33
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

760142:HIPMA RS01660
gene id: 760142:HIPMA_RS01660
uniprot id: F2LTH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

760142:HIPMA RS07915
gene id: 760142:HIPMA_RS07915
uniprot id: F2LTV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

760142:HIPMA RS00740
gene id: 760142:HIPMA_RS00740
uniprot id: F2LX70
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

760142:HIPMA RS07855
gene id: 760142:HIPMA_RS07855
uniprot id: F2LTU7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

760142:HIPMA RS07795
gene id: 760142:HIPMA_RS07795
uniprot id: F2LTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

760142:HIPMA RS07110
gene id: 760142:HIPMA_RS07110
uniprot id: F2LXU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

760142:HIPMA RS02150
gene id: 760142:HIPMA_RS02150
uniprot id: F2LTY9
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

760142:HIPMA RS09105
gene id: 760142:HIPMA_RS09105
uniprot id: F2LV18
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

760142:HIPMA RS05040
gene id: 760142:HIPMA_RS05040
uniprot id: F2LW09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

760142:HIPMA RS07850
gene id: 760142:HIPMA_RS07850
uniprot id: F2LTU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

760142:HIPMA RS05670
gene id: 760142:HIPMA_RS05670
uniprot id: F2LWC9
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

760142:HIPMA RS04145
gene id: 760142:HIPMA_RS04145
uniprot id: F2LVJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

760142:HIPMA RS07600
gene id: 760142:HIPMA_RS07600
uniprot id: F2LTP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS03050
gene id: 760142:HIPMA_RS03050
uniprot id: F2LUV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

760142:HIPMA RS02025
gene id: 760142:HIPMA_RS02025
uniprot id: F2LTX1
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

760142:HIPMA RS04470
gene id: 760142:HIPMA_RS04470
uniprot id: F2LVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

760142:HIPMA RS00940
gene id: 760142:HIPMA_RS00940
uniprot id: F2LXH9
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS05145
gene id: 760142:HIPMA_RS05145
uniprot id: F2LW30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

760142:HIPMA RS01360
gene id: 760142:HIPMA_RS01360
uniprot id: F2LXX4
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS02885
gene id: 760142:HIPMA_RS02885
uniprot id: F2LUS7
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS08420
gene id: 760142:HIPMA_RS08420
uniprot id: F2LUI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

760142:HIPMA RS05315
gene id: 760142:HIPMA_RS05315
uniprot id: F2LW64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

760142:HIPMA RS02600
gene id: 760142:HIPMA_RS02600
uniprot id: F2LUE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

760142:HIPMA RS02160
gene id: 760142:HIPMA_RS02160
uniprot id: F2LTZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

760142:HIPMA RS07675
gene id: 760142:HIPMA_RS07675
uniprot id: F2LTR1
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

760142:HIPMA RS01715
gene id: 760142:HIPMA_RS01715
uniprot id: F2LTI4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS07755
gene id: 760142:HIPMA_RS07755
uniprot id: F2LTS7
names: Similarity
messages: Belongs to the P(II) protein family.

760142:HIPMA RS05470
gene id: 760142:HIPMA_RS05470
uniprot id: F2LW91
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS07005
gene id: 760142:HIPMA_RS07005
uniprot id: F2LXS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

760142:HIPMA RS06785
gene id: 760142:HIPMA_RS06785
uniprot id: F2LXF7
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS08940
gene id: 760142:HIPMA_RS08940
uniprot id: F2LX35
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS03975
gene id: 760142:HIPMA_RS03975
uniprot id: F2LVF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

760142:HIPMA RS05920
gene id: 760142:HIPMA_RS05920
uniprot id: F2LWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

760142:HIPMA RS00345
gene id: 760142:HIPMA_RS00345
uniprot id: F2LWS3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

760142:HIPMA RS04760
gene id: 760142:HIPMA_RS04760
uniprot id: F2LVV7
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS00475
gene id: 760142:HIPMA_RS00475
uniprot id: F2LWV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

760142:HIPMA RS04165
gene id: 760142:HIPMA_RS04165
uniprot id: F2LVJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

760142:HIPMA RS04240
gene id: 760142:HIPMA_RS04240
uniprot id: F2LVL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

760142:HIPMA RS01260
gene id: 760142:HIPMA_RS01260
uniprot id: F2LXP0
names: Similarity
messages: Belongs to the GSP E family.

760142:HIPMA RS02585
gene id: 760142:HIPMA_RS02585
uniprot id: F2LUE6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

760142:HIPMA RS08190
gene id: 760142:HIPMA_RS08190
uniprot id: F2LU73
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

760142:HIPMA RS02300
gene id: 760142:HIPMA_RS02300
uniprot id: F2LU18
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS01175
gene id: 760142:HIPMA_RS01175
uniprot id: F2LXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

760142:HIPMA RS08735
gene id: 760142:HIPMA_RS08735
uniprot id: F2LUP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GmhB family.
messages: Cytoplasm
messages: Monomer.

760142:HIPMA RS01180
gene id: 760142:HIPMA_RS01180
uniprot id: F2LXM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760142:HIPMA RS02665
gene id: 760142:HIPMA_RS02665
uniprot id: F2LUG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

760142:HIPMA RS04495
gene id: 760142:HIPMA_RS04495
uniprot id: F2LVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

760142:HIPMA RS05430
gene id: 760142:HIPMA_RS05430
uniprot id: F2LW83
names: Similarity
messages: Belongs to the threonine synthase family.

760142:HIPMA RS06650
gene id: 760142:HIPMA_RS06650
uniprot id: F2LXD2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

760142:HIPMA RS04455
gene id: 760142:HIPMA_RS04455
uniprot id: F2LVQ0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

760142:HIPMA RS08795
gene id: 760142:HIPMA_RS08795
uniprot id: F2LUX5
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS00010
gene id: 760142:HIPMA_RS00010
uniprot id: F2LWE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

760142:HIPMA RS07535
gene id: 760142:HIPMA_RS07535
uniprot id: F2LY85
names: Subcellular Location Annotation
messages: Cytoplasm

760142:HIPMA RS02500
gene id: 760142:HIPMA_RS02500
uniprot id: F2LUD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

760142:HIPMA RS05640
gene id: 760142:HIPMA_RS05640
uniprot id: F2LWC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS06675
gene id: 760142:HIPMA_RS06675
uniprot id: F2LXD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

760142:HIPMA RS03990
gene id: 760142:HIPMA_RS03990
uniprot id: F2LVG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

760142:HIPMA RS01530
gene id: 760142:HIPMA_RS01530
uniprot id: F2LY07
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS07030
gene id: 760142:HIPMA_RS07030
uniprot id: F2LXS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

760142:HIPMA RS05540
gene id: 760142:HIPMA_RS05540
uniprot id: F2LWA5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

760142:HIPMA RS01385
gene id: 760142:HIPMA_RS01385
uniprot id: F2LXX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS04940
gene id: 760142:HIPMA_RS04940
uniprot id: F2LVZ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

760142:HIPMA RS00800
gene id: 760142:HIPMA_RS00800
uniprot id: F2LX80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS04295
gene id: 760142:HIPMA_RS04295
uniprot id: F2LVM0
names: Similarity
messages: Belongs to the AOR/FOR family.

760142:HIPMA RS08410
gene id: 760142:HIPMA_RS08410
uniprot id: F2LUI5
names: Similarity
messages: Belongs to the leucine-binding protein family.

760142:HIPMA RS00170
gene id: 760142:HIPMA_RS00170
uniprot id: F2LWP0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

760142:HIPMA RS04635
gene id: 760142:HIPMA_RS04635
uniprot id: F2LVT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

760142:HIPMA RS07155
gene id: 760142:HIPMA_RS07155
uniprot id: F2LXV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

760142:HIPMA RS01420
gene id: 760142:HIPMA_RS01420
uniprot id: F2LXY6
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS07825
gene id: 760142:HIPMA_RS07825
uniprot id: F2LTU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

760142:HIPMA RS03860
gene id: 760142:HIPMA_RS03860
uniprot id: F2LVD6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

760142:HIPMA RS04945
gene id: 760142:HIPMA_RS04945
uniprot id: F2LVZ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

760142:HIPMA RS00765
gene id: 760142:HIPMA_RS00765
uniprot id: F2LX75
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

760142:HIPMA RS06970
gene id: 760142:HIPMA_RS06970
uniprot id: F2LXR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

760142:HIPMA RS07315
gene id: 760142:HIPMA_RS07315
uniprot id: F2LY42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

760142:HIPMA RS06780
gene id: 760142:HIPMA_RS06780
uniprot id: F2LXF6
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS07750
gene id: 760142:HIPMA_RS07750
uniprot id: F2LTS6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

760142:HIPMA RS04385
gene id: 760142:HIPMA_RS04385
uniprot id: F2LVN7
names: Similarity
messages: Belongs to the DprA/Smf family.

760142:HIPMA RS00160
gene id: 760142:HIPMA_RS00160
uniprot id: F2LWN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

760142:HIPMA RS08475
gene id: 760142:HIPMA_RS08475
uniprot id: F2LUJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

760142:HIPMA RS05010
gene id: 760142:HIPMA_RS05010
uniprot id: F2LW03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

760142:HIPMA RS08815
gene id: 760142:HIPMA_RS08815
uniprot id: F2LUX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

760142:HIPMA RS01255
gene id: 760142:HIPMA_RS01255
uniprot id: F2LXN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

760142:HIPMA RS01485
gene id: 760142:HIPMA_RS01485
uniprot id: F2LXZ9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

760142:HIPMA RS07310
gene id: 760142:HIPMA_RS07310
uniprot id: F2LY41
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

760142:HIPMA RS01120
gene id: 760142:HIPMA_RS01120
uniprot id: F2LXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

760142:HIPMA RS05285
gene id: 760142:HIPMA_RS05285
uniprot id: F2LW58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

760142:HIPMA RS06360
gene id: 760142:HIPMA_RS06360
uniprot id: F2LX09
names: Similarity
messages: Belongs to the DtxR/MntR family.

760142:HIPMA RS06270
gene id: 760142:HIPMA_RS06270
uniprot id: F2LWZ1
names: Similarity
messages: Belongs to the fabD family.

760142:HIPMA RS00375
gene id: 760142:HIPMA_RS00375
uniprot id: F2LWS9
names: Similarity
messages: Belongs to the peptidase U62 family.

760142:HIPMA RS03505
gene id: 760142:HIPMA_RS03505
uniprot id: F2LV66
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS06745
gene id: 760142:HIPMA_RS06745
uniprot id: F2LXF1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

760142:HIPMA RS07605
gene id: 760142:HIPMA_RS07605
uniprot id: F2LTP6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

760142:HIPMA RS03665
gene id: 760142:HIPMA_RS03665
uniprot id: F2LV97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

760142:HIPMA RS02805
gene id: 760142:HIPMA_RS02805
uniprot id: F2LUR1
names: Similarity
messages: Belongs to the citrate synthase family.

760142:HIPMA RS05660
gene id: 760142:HIPMA_RS05660
uniprot id: F2LWC7
names: Similarity
messages: Belongs to the peptidase A31 family.

760142:HIPMA RS00125
gene id: 760142:HIPMA_RS00125
uniprot id: F2LWN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

760142:HIPMA RS01225
gene id: 760142:HIPMA_RS01225
uniprot id: F2LXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

760142:HIPMA RS00670
gene id: 760142:HIPMA_RS00670
uniprot id: F2LX57
names: Similarity
messages: Belongs to the class-I fumarase family.

760142:HIPMA RS01950
gene id: 760142:HIPMA_RS01950
uniprot id: F2LTN1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

760142:HIPMA RS05200
gene id: 760142:HIPMA_RS05200
uniprot id: F2LW41
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS01280
gene id: 760142:HIPMA_RS01280
uniprot id: F2LXW5
names: Similarity
messages: Belongs to the MEMO1 family.

760142:HIPMA RS05095
gene id: 760142:HIPMA_RS05095
uniprot id: F2LW20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

760142:HIPMA RS07570
gene id: 760142:HIPMA_RS07570
uniprot id: F2LY92
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

760142:HIPMA RS03615
gene id: 760142:HIPMA_RS03615
uniprot id: F2LV87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS07355
gene id: 760142:HIPMA_RS07355
uniprot id: F2LY50
names: Similarity
messages: Belongs to the AlaDH/PNT family.

760142:HIPMA RS04865
gene id: 760142:HIPMA_RS04865
uniprot id: F2LVX8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

760142:HIPMA RS08205
gene id: 760142:HIPMA_RS08205
uniprot id: F2LU76
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

760142:HIPMA RS04210
gene id: 760142:HIPMA_RS04210
uniprot id: F2LVK6
names: Similarity
messages: Belongs to the leucine-binding protein family.

760142:HIPMA RS05535
gene id: 760142:HIPMA_RS05535
uniprot id: F2LWA4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

760142:HIPMA RS02470
gene id: 760142:HIPMA_RS02470
uniprot id: F2LUC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

760142:HIPMA RS01625
gene id: 760142:HIPMA_RS01625
uniprot id: F2LY26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

760142:HIPMA RS06880
gene id: 760142:HIPMA_RS06880
uniprot id: F2LXP8
names: Similarity
messages: Belongs to the LOG family.

760142:HIPMA RS04845
gene id: 760142:HIPMA_RS04845
uniprot id: F2LVX4
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS00355
gene id: 760142:HIPMA_RS00355
uniprot id: F2LWS5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

760142:HIPMA RS08455
gene id: 760142:HIPMA_RS08455
uniprot id: F2LUJ4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

760142:HIPMA RS07810
gene id: 760142:HIPMA_RS07810
uniprot id: F2LTT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

760142:HIPMA RS09095
gene id: 760142:HIPMA_RS09095
uniprot id: F2LUU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the QueH family.
messages: Belongs to the RNase HII family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

760142:HIPMA RS06605
gene id: 760142:HIPMA_RS06605
uniprot id: F2LXC3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

760142:HIPMA RS06295
gene id: 760142:HIPMA_RS06295
uniprot id: F2LWZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

760142:HIPMA RS05100
gene id: 760142:HIPMA_RS05100
uniprot id: F2LW21
names: Subcellular Location Annotation
messages: Periplasm

760142:HIPMA RS06905
gene id: 760142:HIPMA_RS06905
uniprot id: F2LXQ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

760142:HIPMA RS05345
gene id: 760142:HIPMA_RS05345
uniprot id: F2LW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS02000
gene id: 760142:HIPMA_RS02000
uniprot id: F2LTM1
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

760142:HIPMA RS06645
gene id: 760142:HIPMA_RS06645
uniprot id: F2LXD1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

760142:HIPMA RS03085
gene id: 760142:HIPMA_RS03085
uniprot id: F2LUW3
names: Similarity
messages: Belongs to the GARS family.

760142:HIPMA RS05780
gene id: 760142:HIPMA_RS05780
uniprot id: F2LWH5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

760142:HIPMA RS09255
gene id: 760142:HIPMA_RS09255
uniprot id: F2LTT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

760142:HIPMA RS03960
gene id: 760142:HIPMA_RS03960
uniprot id: F2LVF6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS02870
gene id: 760142:HIPMA_RS02870
uniprot id: F2LUS4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

760142:HIPMA RS04170
gene id: 760142:HIPMA_RS04170
uniprot id: F2LVJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

760142:HIPMA RS09195
gene id: 760142:HIPMA_RS09195
uniprot id: F2LWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

760142:HIPMA RS04480
gene id: 760142:HIPMA_RS04480
uniprot id: F2LVQ5
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

760142:HIPMA RS03670
gene id: 760142:HIPMA_RS03670
uniprot id: F2LV98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

760142:HIPMA RS06170
gene id: 760142:HIPMA_RS06170
uniprot id: F2LWX1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

760142:HIPMA RS01785
gene id: 760142:HIPMA_RS01785
uniprot id: F2LTJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

760142:HIPMA RS05185
gene id: 760142:HIPMA_RS05185
uniprot id: F2LW38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS06055
gene id: 760142:HIPMA_RS06055
uniprot id: F2LWM4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

760142:HIPMA RS01290
gene id: 760142:HIPMA_RS01290
uniprot id: F2LXW7
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

760142:HIPMA RS03700
gene id: 760142:HIPMA_RS03700
uniprot id: F2LVA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

760142:HIPMA RS04520
gene id: 760142:HIPMA_RS04520
uniprot id: F2LVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

760142:HIPMA RS01640
gene id: 760142:HIPMA_RS01640
uniprot id: F2LY29
names: Similarity
messages: Belongs to the band 7/mec-2 family.

760142:HIPMA RS00020
gene id: 760142:HIPMA_RS00020
uniprot id: F2LWE2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

760142:HIPMA RS06975
gene id: 760142:HIPMA_RS06975
uniprot id: F2LXR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

760142:HIPMA RS01760
gene id: 760142:HIPMA_RS01760
uniprot id: F2LTJ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS06555
gene id: 760142:HIPMA_RS06555
uniprot id: F2LXB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

760142:HIPMA RS05600
gene id: 760142:HIPMA_RS05600
uniprot id: F2LWB5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

760142:HIPMA RS06550
gene id: 760142:HIPMA_RS06550
uniprot id: F2LXB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

760142:HIPMA RS06850
gene id: 760142:HIPMA_RS06850
uniprot id: F2LXP3
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS07635
gene id: 760142:HIPMA_RS07635
uniprot id: F2LTQ3
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

760142:HIPMA RS00685
gene id: 760142:HIPMA_RS00685
uniprot id: F2LX60
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

760142:HIPMA RS03175
gene id: 760142:HIPMA_RS03175
uniprot id: F2LV02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS01185
gene id: 760142:HIPMA_RS01185
uniprot id: F2LXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

760142:HIPMA RS07040
gene id: 760142:HIPMA_RS07040
uniprot id: F2LXS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

760142:HIPMA RS01975
gene id: 760142:HIPMA_RS01975
uniprot id: F2LTN6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

760142:HIPMA RS02230
gene id: 760142:HIPMA_RS02230
uniprot id: F2LU05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

760142:HIPMA RS06235
gene id: 760142:HIPMA_RS06235
uniprot id: F2LWY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

760142:HIPMA RS04920
gene id: 760142:HIPMA_RS04920
uniprot id: F2LVY9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

760142:HIPMA RS00515
gene id: 760142:HIPMA_RS00515
uniprot id: F2LX28
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS08390
gene id: 760142:HIPMA_RS08390
uniprot id: F2LUI1
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS06040
gene id: 760142:HIPMA_RS06040
uniprot id: F2LWM1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

760142:HIPMA RS03755
gene id: 760142:HIPMA_RS03755
uniprot id: F2LVB5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

760142:HIPMA RS02335
gene id: 760142:HIPMA_RS02335
uniprot id: F2LU25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

760142:HIPMA RS06255
gene id: 760142:HIPMA_RS06255
uniprot id: F2LWY8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

760142:HIPMA RS06405
gene id: 760142:HIPMA_RS06405
uniprot id: F2LX18
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS00545
gene id: 760142:HIPMA_RS00545
uniprot id: F2LX34
names: Similarity
messages: Belongs to the serpin family.

760142:HIPMA RS01390
gene id: 760142:HIPMA_RS01390
uniprot id: F2LXY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

760142:HIPMA RS03850
gene id: 760142:HIPMA_RS03850
uniprot id: F2LVD5
names: Subcellular Location Annotation
messages: Membrane

760142:HIPMA RS00830
gene id: 760142:HIPMA_RS00830
uniprot id: F2LX86
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

760142:HIPMA RS05135
gene id: 760142:HIPMA_RS05135
uniprot id: F2LW28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

760142:HIPMA RS04765
gene id: 760142:HIPMA_RS04765
uniprot id: F2LVV8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

760142:HIPMA RS01110
gene id: 760142:HIPMA_RS01110
uniprot id: F2LXL0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

760142:HIPMA RS05545
gene id: 760142:HIPMA_RS05545
uniprot id: F2LWA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

760142:HIPMA RS07485
gene id: 760142:HIPMA_RS07485
uniprot id: F2LY76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

760142:HIPMA RS04630
gene id: 760142:HIPMA_RS04630
uniprot id: F2LVT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

760142:HIPMA RS01695
gene id: 760142:HIPMA_RS01695
uniprot id: F2LTI0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

760142:HIPMA RS00135
gene id: 760142:HIPMA_RS00135
uniprot id: F2LWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

760142:HIPMA RS02140
gene id: 760142:HIPMA_RS02140
uniprot id: F2LTY7
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

760142:HIPMA RS06425
gene id: 760142:HIPMA_RS06425
uniprot id: F2LTX0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

760142:HIPMA RS07480
gene id: 760142:HIPMA_RS07480
uniprot id: F2LY75
names: Similarity
messages: Belongs to the NusB family.

760142:HIPMA RS02650
gene id: 760142:HIPMA_RS02650
uniprot id: F2LUF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm