758793:BRPE64 RS02975
gene id: 758793:BRPE64_RS02975
uniprot id: R4WFQ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS09145
gene id: 758793:BRPE64_RS09145
uniprot id: R4WRT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758793:BRPE64 RS04235
gene id: 758793:BRPE64_RS04235
uniprot id: R4WUM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

758793:BRPE64 RS19570
gene id: 758793:BRPE64_RS19570
uniprot id: R4WMU8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS29540
gene id: 758793:BRPE64_RS29540
uniprot id: R4X101
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS09390
gene id: 758793:BRPE64_RS09390
uniprot id: R4WZ91
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19965
gene id: 758793:BRPE64_RS19965
uniprot id: R4X300
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19315
gene id: 758793:BRPE64_RS19315
uniprot id: R4WMG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

758793:BRPE64 RS31115
gene id: 758793:BRPE64_RS31115
uniprot id: A0A060PKE7
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

758793:BRPE64 RS04360
gene id: 758793:BRPE64_RS04360
uniprot id: R4WFW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

758793:BRPE64 RS25400
gene id: 758793:BRPE64_RS25400
uniprot id: R4WR81
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

758793:BRPE64 RS23875
gene id: 758793:BRPE64_RS23875
uniprot id: R4X3W3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS08375
gene id: 758793:BRPE64_RS08375
uniprot id: R4WHE8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS27965
gene id: 758793:BRPE64_RS27965
uniprot id: R4X3S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS30170
gene id: 758793:BRPE64_RS30170
uniprot id: R4X184
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

758793:BRPE64 RS12035
gene id: 758793:BRPE64_RS12035
uniprot id: R4WIR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

758793:BRPE64 RS00240
gene id: 758793:BRPE64_RS00240
uniprot id: R4WSF7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

758793:BRPE64 RS28410
gene id: 758793:BRPE64_RS28410
uniprot id: R4X4Z5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS14085
gene id: 758793:BRPE64_RS14085
uniprot id: R4WJS0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

758793:BRPE64 RS11725
gene id: 758793:BRPE64_RS11725
uniprot id: R4WY95
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

758793:BRPE64 RS17830
gene id: 758793:BRPE64_RS17830
uniprot id: R4WLJ0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758793:BRPE64 RS12355
gene id: 758793:BRPE64_RS12355
uniprot id: R4WTM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

758793:BRPE64 RS06285
gene id: 758793:BRPE64_RS06285
uniprot id: R4WGR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS11835
gene id: 758793:BRPE64_RS11835
uniprot id: R4X041
names: Similarity
messages: Belongs to the peptidase M24B family.

758793:BRPE64 RS02740
gene id: 758793:BRPE64_RS02740
uniprot id: R4WFN0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

758793:BRPE64 RS18900
gene id: 758793:BRPE64_RS18900
uniprot id: R4X2K1
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

758793:BRPE64 RS20780
gene id: 758793:BRPE64_RS20780
uniprot id: R4X1E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS09525
gene id: 758793:BRPE64_RS09525
uniprot id: R4WHP8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758793:BRPE64 RS09960
gene id: 758793:BRPE64_RS09960
uniprot id: R4WHY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

758793:BRPE64 RS10430
gene id: 758793:BRPE64_RS10430
uniprot id: R4WHZ5
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

758793:BRPE64 RS23220
gene id: 758793:BRPE64_RS23220
uniprot id: R4X2B4
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS00765
gene id: 758793:BRPE64_RS00765
uniprot id: R4WEY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS13545
gene id: 758793:BRPE64_RS13545
uniprot id: R4WJC5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

758793:BRPE64 RS02010
gene id: 758793:BRPE64_RS02010
uniprot id: R4WF45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

758793:BRPE64 RS19035
gene id: 758793:BRPE64_RS19035
uniprot id: R4WMH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS11550
gene id: 758793:BRPE64_RS11550
uniprot id: R4WIM5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

758793:BRPE64 RS00930
gene id: 758793:BRPE64_RS00930
uniprot id: R4WF05
names: Similarity
messages: Belongs to the peptidase S41A family.

758793:BRPE64 RS02455
gene id: 758793:BRPE64_RS02455
uniprot id: R4WFK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

758793:BRPE64 RS12390
gene id: 758793:BRPE64_RS12390
uniprot id: R4X0C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

758793:BRPE64 RS24805
gene id: 758793:BRPE64_RS24805
uniprot id: R4X2W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

758793:BRPE64 RS25440
gene id: 758793:BRPE64_RS25440
uniprot id: R4WR92
names: Similarity
messages: Belongs to the manganese catalase family.

758793:BRPE64 RS13520
gene id: 758793:BRPE64_RS13520
uniprot id: R4X0P9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

758793:BRPE64 RS15770
gene id: 758793:BRPE64_RS15770
uniprot id: R4WKP0
names: Similarity
messages: Belongs to the citrate synthase family.

758793:BRPE64 RS08475
gene id: 758793:BRPE64_RS08475
uniprot id: R4WRF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

758793:BRPE64 RS04465
gene id: 758793:BRPE64_RS04465
uniprot id: R4WP61
names: Similarity
messages: Belongs to the DEAD box helicase family.

758793:BRPE64 RS00600
gene id: 758793:BRPE64_RS00600
uniprot id: R4WEN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

758793:BRPE64 RS25760
gene id: 758793:BRPE64_RS25760
uniprot id: R4WR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS01030
gene id: 758793:BRPE64_RS01030
uniprot id: R4WF15
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS11380
gene id: 758793:BRPE64_RS11380
uniprot id: R4WIE4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

758793:BRPE64 RS28240
gene id: 758793:BRPE64_RS28240
uniprot id: R4X4X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS06195
gene id: 758793:BRPE64_RS06195
uniprot id: R4WVS0
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

758793:BRPE64 RS00120
gene id: 758793:BRPE64_RS00120
uniprot id: R4WSD4
names: Similarity
messages: Belongs to the type IA topoisomerase family.

758793:BRPE64 RS04300
gene id: 758793:BRPE64_RS04300
uniprot id: R4WP14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

758793:BRPE64 RS17070
gene id: 758793:BRPE64_RS17070
uniprot id: R4WL76
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS00965
gene id: 758793:BRPE64_RS00965
uniprot id: R4WSU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

758793:BRPE64 RS00440
gene id: 758793:BRPE64_RS00440
uniprot id: R4WEV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

758793:BRPE64 RS05470
gene id: 758793:BRPE64_RS05470
uniprot id: R4WG98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

758793:BRPE64 RS22020
gene id: 758793:BRPE64_RS22020
uniprot id: R4WNY5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS15575
gene id: 758793:BRPE64_RS15575
uniprot id: R4X1G1
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

758793:BRPE64 RS04255
gene id: 758793:BRPE64_RS04255
uniprot id: R4WP04
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS28530
gene id: 758793:BRPE64_RS28530
uniprot id: R4WT39
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS22045
gene id: 758793:BRPE64_RS22045
uniprot id: R4WNZ0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

758793:BRPE64 RS01595
gene id: 758793:BRPE64_RS01595
uniprot id: R4WEZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS08405
gene id: 758793:BRPE64_RS08405
uniprot id: R4WX16
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

758793:BRPE64 RS06300
gene id: 758793:BRPE64_RS06300
uniprot id: R4WY31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

758793:BRPE64 RS29135
gene id: 758793:BRPE64_RS29135
uniprot id: R4X428
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758793:BRPE64 RS08630
gene id: 758793:BRPE64_RS08630
uniprot id: R4WX50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS09360
gene id: 758793:BRPE64_RS09360
uniprot id: R4WHM1
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

758793:BRPE64 RS24470
gene id: 758793:BRPE64_RS24470
uniprot id: R4WZ36
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05270
gene id: 758793:BRPE64_RS05270
uniprot id: R4WG82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS25875
gene id: 758793:BRPE64_RS25875
uniprot id: R4X4D3
names: Similarity
messages: Belongs to the GST superfamily.

758793:BRPE64 RS03925
gene id: 758793:BRPE64_RS03925
uniprot id: R4WUG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

758793:BRPE64 RS10715
gene id: 758793:BRPE64_RS10715
uniprot id: R4WXW8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS31740
gene id: 758793:BRPE64_RS31740
uniprot id: A0A060PRD1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

758793:BRPE64 RS04265
gene id: 758793:BRPE64_RS04265
uniprot id: R4WXB3
names: Similarity
messages: Belongs to the PhzF family.

758793:BRPE64 RS14895
gene id: 758793:BRPE64_RS14895
uniprot id: R4WV05
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS06665
gene id: 758793:BRPE64_RS06665
uniprot id: R4WW07
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS22210
gene id: 758793:BRPE64_RS22210
uniprot id: R4WPA3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

758793:BRPE64 RS05825
gene id: 758793:BRPE64_RS05825
uniprot id: R4WGL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

758793:BRPE64 RS18365
gene id: 758793:BRPE64_RS18365
uniprot id: R4WWV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

758793:BRPE64 RS06320
gene id: 758793:BRPE64_RS06320
uniprot id: R4WVU1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS22750
gene id: 758793:BRPE64_RS22750
uniprot id: R4X3M7
names: Similarity
messages: Belongs to the DEAD box helicase family.

758793:BRPE64 RS18570
gene id: 758793:BRPE64_RS18570
uniprot id: R4X2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS01885
gene id: 758793:BRPE64_RS01885
uniprot id: R4WTC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS25430
gene id: 758793:BRPE64_RS25430
uniprot id: R4X494
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

758793:BRPE64 RS15860
gene id: 758793:BRPE64_RS15860
uniprot id: R4WKR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

758793:BRPE64 RS06775
gene id: 758793:BRPE64_RS06775
uniprot id: R4WQH7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

758793:BRPE64 RS02615
gene id: 758793:BRPE64_RS02615
uniprot id: R4WTU8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS01690
gene id: 758793:BRPE64_RS01690
uniprot id: R4WW09
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

758793:BRPE64 RS14640
gene id: 758793:BRPE64_RS14640
uniprot id: R4WK42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

758793:BRPE64 RS19430
gene id: 758793:BRPE64_RS19430
uniprot id: R4WMS8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

758793:BRPE64 RS16780
gene id: 758793:BRPE64_RS16780
uniprot id: R4WL36
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05560
gene id: 758793:BRPE64_RS05560
uniprot id: R4WXU7
names: Similarity
messages: Belongs to the universal stress protein A family.

758793:BRPE64 RS01860
gene id: 758793:BRPE64_RS01860
uniprot id: R4WTB4
names: Similarity
messages: Belongs to the peptidase U62 family.

758793:BRPE64 RS31470
gene id: 758793:BRPE64_RS31470
uniprot id: A0A060PKN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS01525
gene id: 758793:BRPE64_RS01525
uniprot id: R4WEY7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

758793:BRPE64 RS06765
gene id: 758793:BRPE64_RS06765
uniprot id: R4WGR0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS11050
gene id: 758793:BRPE64_RS11050
uniprot id: R4WZU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

758793:BRPE64 RS29400
gene id: 758793:BRPE64_RS29400
uniprot id: R4X563
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS10230
gene id: 758793:BRPE64_RS10230
uniprot id: R4WHW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

758793:BRPE64 RS23545
gene id: 758793:BRPE64_RS23545
uniprot id: R4WPU4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS08315
gene id: 758793:BRPE64_RS08315
uniprot id: R4WYV1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758793:BRPE64 RS31710
gene id: 758793:BRPE64_RS31710
uniprot id: A0A060PHD8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758793:BRPE64 RS10145
gene id: 758793:BRPE64_RS10145
uniprot id: R4WZI9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS01500
gene id: 758793:BRPE64_RS01500
uniprot id: R4WVX9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

758793:BRPE64 RS00885
gene id: 758793:BRPE64_RS00885
uniprot id: R4WM67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

758793:BRPE64 RS12015
gene id: 758793:BRPE64_RS12015
uniprot id: R4WIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

758793:BRPE64 RS13080
gene id: 758793:BRPE64_RS13080
uniprot id: R4WJB1
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

758793:BRPE64 RS16055
gene id: 758793:BRPE64_RS16055
uniprot id: R4WKV2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS17360
gene id: 758793:BRPE64_RS17360
uniprot id: R4X235
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05700
gene id: 758793:BRPE64_RS05700
uniprot id: R4WXW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

758793:BRPE64 RS02700
gene id: 758793:BRPE64_RS02700
uniprot id: R4WFM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

758793:BRPE64 RS03055
gene id: 758793:BRPE64_RS03055
uniprot id: R4WU29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

758793:BRPE64 RS19935
gene id: 758793:BRPE64_RS19935
uniprot id: R4WXH4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

758793:BRPE64 RS09020
gene id: 758793:BRPE64_RS09020
uniprot id: R4WHM5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

758793:BRPE64 RS16935
gene id: 758793:BRPE64_RS16935
uniprot id: R4WLE7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

758793:BRPE64 RS08120
gene id: 758793:BRPE64_RS08120
uniprot id: R4WR91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758793:BRPE64 RS10065
gene id: 758793:BRPE64_RS10065
uniprot id: R4WHV0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS12125
gene id: 758793:BRPE64_RS12125
uniprot id: R4X095
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS05070
gene id: 758793:BRPE64_RS05070
uniprot id: R4WXN8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS04935
gene id: 758793:BRPE64_RS04935
uniprot id: R4WPJ9
names: Similarity
messages: Belongs to the peptidase S11 family.

758793:BRPE64 RS14745
gene id: 758793:BRPE64_RS14745
uniprot id: R4WK57
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS05720
gene id: 758793:BRPE64_RS05720
uniprot id: R4WXW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

758793:BRPE64 RS04640
gene id: 758793:BRPE64_RS04640
uniprot id: R4WXH1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

758793:BRPE64 RS06240
gene id: 758793:BRPE64_RS06240
uniprot id: R4WQ65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

758793:BRPE64 RS07620
gene id: 758793:BRPE64_RS07620
uniprot id: R4WYN0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

758793:BRPE64 RS03715
gene id: 758793:BRPE64_RS03715
uniprot id: R4WX55
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

758793:BRPE64 RS30395
gene id: 758793:BRPE64_RS30395
uniprot id: R4X4D2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS07555
gene id: 758793:BRPE64_RS07555
uniprot id: R4WH59
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

758793:BRPE64 RS30255
gene id: 758793:BRPE64_RS30255
uniprot id: R4WU37
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS15495
gene id: 758793:BRPE64_RS15495
uniprot id: R4WKI3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS04780
gene id: 758793:BRPE64_RS04780
uniprot id: R4WXK2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS14295
gene id: 758793:BRPE64_RS14295
uniprot id: R4WJQ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS01985
gene id: 758793:BRPE64_RS01985
uniprot id: R4WF42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS13105
gene id: 758793:BRPE64_RS13105
uniprot id: R4WJB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

758793:BRPE64 RS16575
gene id: 758793:BRPE64_RS16575
uniprot id: R4WKX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS27925
gene id: 758793:BRPE64_RS27925
uniprot id: R4WSL5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS32095
gene id: 758793:BRPE64_RS32095
uniprot id: R4WPE4
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS27805
gene id: 758793:BRPE64_RS27805
uniprot id: R4WSI1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS30700
gene id: 758793:BRPE64_RS30700
uniprot id: R4X1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS07560
gene id: 758793:BRPE64_RS07560
uniprot id: R4WQZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

758793:BRPE64 RS19740
gene id: 758793:BRPE64_RS19740
uniprot id: R4WMM5
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

758793:BRPE64 RS31265
gene id: 758793:BRPE64_RS31265
uniprot id: A0A060PQY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS23620
gene id: 758793:BRPE64_RS23620
uniprot id: R4WPW2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758793:BRPE64 RS03750
gene id: 758793:BRPE64_RS03750
uniprot id: R4WFX2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS18310
gene id: 758793:BRPE64_RS18310
uniprot id: R4X2D9
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

758793:BRPE64 RS24980
gene id: 758793:BRPE64_RS24980
uniprot id: R4WQX0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS15935
gene id: 758793:BRPE64_RS15935
uniprot id: R4WVK2
names: Similarity
messages: Belongs to the peptidase S58 family.

758793:BRPE64 RS30070
gene id: 758793:BRPE64_RS30070
uniprot id: R4WU28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS23525
gene id: 758793:BRPE64_RS23525
uniprot id: R4WPT9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS26110
gene id: 758793:BRPE64_RS26110
uniprot id: R4X3A6
names: Similarity
messages: Belongs to the GSP E family.

758793:BRPE64 RS01145
gene id: 758793:BRPE64_RS01145
uniprot id: R4WEU0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

758793:BRPE64 RS19545
gene id: 758793:BRPE64_RS19545
uniprot id: R4WMU5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS27970
gene id: 758793:BRPE64_RS27970
uniprot id: R4X4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS22375
gene id: 758793:BRPE64_RS22375
uniprot id: R4X200
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

758793:BRPE64 RS02710
gene id: 758793:BRPE64_RS02710
uniprot id: R4WWR1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

758793:BRPE64 RS14755
gene id: 758793:BRPE64_RS14755
uniprot id: R4WZC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

758793:BRPE64 RS11200
gene id: 758793:BRPE64_RS11200
uniprot id: R4WIB1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS03985
gene id: 758793:BRPE64_RS03985
uniprot id: R4WFR7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

758793:BRPE64 RS01970
gene id: 758793:BRPE64_RS01970
uniprot id: R4WMS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

758793:BRPE64 RS31530
gene id: 758793:BRPE64_RS31530
uniprot id: A0A060PR49
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS28050
gene id: 758793:BRPE64_RS28050
uniprot id: R4WSP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS03910
gene id: 758793:BRPE64_RS03910
uniprot id: R4WFQ8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS16940
gene id: 758793:BRPE64_RS16940
uniprot id: R4WW38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

758793:BRPE64 RS06620
gene id: 758793:BRPE64_RS06620
uniprot id: R4WY82
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

758793:BRPE64 RS01135
gene id: 758793:BRPE64_RS01135
uniprot id: R4WSX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

758793:BRPE64 RS08920
gene id: 758793:BRPE64_RS08920
uniprot id: R4WRN6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

758793:BRPE64 RS14335
gene id: 758793:BRPE64_RS14335
uniprot id: R4WZ76
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

758793:BRPE64 RS01895
gene id: 758793:BRPE64_RS01895
uniprot id: R4WF30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

758793:BRPE64 RS16300
gene id: 758793:BRPE64_RS16300
uniprot id: R4WL04
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS11795
gene id: 758793:BRPE64_RS11795
uniprot id: R4WYA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

758793:BRPE64 RS25595
gene id: 758793:BRPE64_RS25595
uniprot id: R4X4A7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS05940
gene id: 758793:BRPE64_RS05940
uniprot id: R4WGF5
names: Similarity
messages: Belongs to the allantoicase family.

758793:BRPE64 RS11545
gene id: 758793:BRPE64_RS11545
uniprot id: R4WIG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

758793:BRPE64 RS20285
gene id: 758793:BRPE64_RS20285
uniprot id: R4WMX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

758793:BRPE64 RS01250
gene id: 758793:BRPE64_RS01250
uniprot id: R4WEV2
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

758793:BRPE64 RS27765
gene id: 758793:BRPE64_RS27765
uniprot id: R4WSG8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

758793:BRPE64 RS08495
gene id: 758793:BRPE64_RS08495
uniprot id: R4WHG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS28685
gene id: 758793:BRPE64_RS28685
uniprot id: R4X0Q9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

758793:BRPE64 RS10450
gene id: 758793:BRPE64_RS10450
uniprot id: R4WHZ8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

758793:BRPE64 RS22545
gene id: 758793:BRPE64_RS22545
uniprot id: R4X221
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS13665
gene id: 758793:BRPE64_RS13665
uniprot id: R4WYY2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

758793:BRPE64 RS10795
gene id: 758793:BRPE64_RS10795
uniprot id: R4WSR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

758793:BRPE64 RS21785
gene id: 758793:BRPE64_RS21785
uniprot id: R4WNV5
names: Similarity
messages: Belongs to the AHA1 family.

758793:BRPE64 RS23185
gene id: 758793:BRPE64_RS23185
uniprot id: R4X3R1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS08165
gene id: 758793:BRPE64_RS08165
uniprot id: R4WR99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

758793:BRPE64 RS02195
gene id: 758793:BRPE64_RS02195
uniprot id: R4WWC4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS21490
gene id: 758793:BRPE64_RS21490
uniprot id: R4X3C9
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

758793:BRPE64 RS27710
gene id: 758793:BRPE64_RS27710
uniprot id: R4X4T4
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS06950
gene id: 758793:BRPE64_RS06950
uniprot id: R4WYC8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS15570
gene id: 758793:BRPE64_RS15570
uniprot id: R4WZM1
names: Similarity
messages: Belongs to the Gfa family.

758793:BRPE64 RS24270
gene id: 758793:BRPE64_RS24270
uniprot id: R4WQ96
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

758793:BRPE64 RS10240
gene id: 758793:BRPE64_RS10240
uniprot id: R4WSF4
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

758793:BRPE64 RS17775
gene id: 758793:BRPE64_RS17775
uniprot id: R4X0E0
names: Similarity
messages: Belongs to the NodU/CmcH family.

758793:BRPE64 RS16865
gene id: 758793:BRPE64_RS16865
uniprot id: R4WW28
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS03225
gene id: 758793:BRPE64_RS03225
uniprot id: R4WNH7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS02545
gene id: 758793:BRPE64_RS02545
uniprot id: R4WWN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS31575
gene id: 758793:BRPE64_RS31575
uniprot id: A0A060PR70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

758793:BRPE64 RS31465
gene id: 758793:BRPE64_RS31465
uniprot id: A0A060PR34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

758793:BRPE64 RS15525
gene id: 758793:BRPE64_RS15525
uniprot id: R4WZL6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

758793:BRPE64 RS09355
gene id: 758793:BRPE64_RS09355
uniprot id: R4WZ87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

758793:BRPE64 RS18930
gene id: 758793:BRPE64_RS18930
uniprot id: R4WM61
names: Similarity
messages: Belongs to the peptidase A24 family.

758793:BRPE64 RS20670
gene id: 758793:BRPE64_RS20670
uniprot id: R4WXR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

758793:BRPE64 RS08925
gene id: 758793:BRPE64_RS08925
uniprot id: R4WX84
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

758793:BRPE64 RS14035
gene id: 758793:BRPE64_RS14035
uniprot id: R4WZ34
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

758793:BRPE64 RS25420
gene id: 758793:BRPE64_RS25420
uniprot id: R4WZE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

758793:BRPE64 RS06595
gene id: 758793:BRPE64_RS06595
uniprot id: R4WY78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

758793:BRPE64 RS04655
gene id: 758793:BRPE64_RS04655
uniprot id: R4WPB0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

758793:BRPE64 RS02080
gene id: 758793:BRPE64_RS02080
uniprot id: R4WF56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

758793:BRPE64 RS09335
gene id: 758793:BRPE64_RS09335
uniprot id: R4WHL8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS11025
gene id: 758793:BRPE64_RS11025
uniprot id: R4WZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

758793:BRPE64 RS01195
gene id: 758793:BRPE64_RS01195
uniprot id: R4WSY1
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

758793:BRPE64 RS24215
gene id: 758793:BRPE64_RS24215
uniprot id: R4X2N8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS25640
gene id: 758793:BRPE64_RS25640
uniprot id: R4X4B1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS08620
gene id: 758793:BRPE64_RS08620
uniprot id: R4WHH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS27240
gene id: 758793:BRPE64_RS27240
uniprot id: R4X037
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

758793:BRPE64 RS15215
gene id: 758793:BRPE64_RS15215
uniprot id: R4X1C3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS10600
gene id: 758793:BRPE64_RS10600
uniprot id: R4WZP1
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

758793:BRPE64 RS26375
gene id: 758793:BRPE64_RS26375
uniprot id: R4X4H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

758793:BRPE64 RS17375
gene id: 758793:BRPE64_RS17375
uniprot id: R4X099
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

758793:BRPE64 RS28960
gene id: 758793:BRPE64_RS28960
uniprot id: R4X528
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS26870
gene id: 758793:BRPE64_RS26870
uniprot id: R4X3G6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

758793:BRPE64 RS10255
gene id: 758793:BRPE64_RS10255
uniprot id: R4WHX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

758793:BRPE64 RS14685
gene id: 758793:BRPE64_RS14685
uniprot id: R4WK50
names: Similarity
messages: Belongs to the HisA/HisF family.

758793:BRPE64 RS02770
gene id: 758793:BRPE64_RS02770
uniprot id: R4WN96
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS31435
gene id: 758793:BRPE64_RS31435
uniprot id: A0A060PH56
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

758793:BRPE64 RS13180
gene id: 758793:BRPE64_RS13180
uniprot id: R4WJC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

758793:BRPE64 RS29460
gene id: 758793:BRPE64_RS29460
uniprot id: R4WTM9
names: Similarity
messages: Belongs to the UxaA family.

758793:BRPE64 RS13580
gene id: 758793:BRPE64_RS13580
uniprot id: R4WYX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS09640
gene id: 758793:BRPE64_RS09640
uniprot id: R4WZD1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

758793:BRPE64 RS11845
gene id: 758793:BRPE64_RS11845
uniprot id: R4WTC6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

758793:BRPE64 RS10630
gene id: 758793:BRPE64_RS10630
uniprot id: R4WI22
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

758793:BRPE64 RS06545
gene id: 758793:BRPE64_RS06545
uniprot id: R4WGN2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

758793:BRPE64 RS17090
gene id: 758793:BRPE64_RS17090
uniprot id: R4WL79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

758793:BRPE64 RS18050
gene id: 758793:BRPE64_RS18050
uniprot id: R4WLX2
names: Subcellular Location Annotation
messages: Periplasm

758793:BRPE64 RS24020
gene id: 758793:BRPE64_RS24020
uniprot id: R4WYY8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS18620
gene id: 758793:BRPE64_RS18620
uniprot id: R4WLZ8
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

758793:BRPE64 RS10800
gene id: 758793:BRPE64_RS10800
uniprot id: R4WXX9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758793:BRPE64 RS26905
gene id: 758793:BRPE64_RS26905
uniprot id: R4WRY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 37 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.

758793:BRPE64 RS10740
gene id: 758793:BRPE64_RS10740
uniprot id: R4WZQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS07645
gene id: 758793:BRPE64_RS07645
uniprot id: R4WYN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

758793:BRPE64 RS21320
gene id: 758793:BRPE64_RS21320
uniprot id: R4X3A7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS18370
gene id: 758793:BRPE64_RS18370
uniprot id: R4X0K7
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

758793:BRPE64 RS09945
gene id: 758793:BRPE64_RS09945
uniprot id: R4WXM5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

758793:BRPE64 RS27110
gene id: 758793:BRPE64_RS27110
uniprot id: R4WS84
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

758793:BRPE64 RS06780
gene id: 758793:BRPE64_RS06780
uniprot id: R4WYA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

758793:BRPE64 RS05205
gene id: 758793:BRPE64_RS05205
uniprot id: R4WPP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

758793:BRPE64 RS04920
gene id: 758793:BRPE64_RS04920
uniprot id: R4WV40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

758793:BRPE64 RS22735
gene id: 758793:BRPE64_RS22735
uniprot id: R4WPK1
names: Similarity
messages: Belongs to the TPP enzyme family.

758793:BRPE64 RS05740
gene id: 758793:BRPE64_RS05740
uniprot id: R4WVI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

758793:BRPE64 RS13675
gene id: 758793:BRPE64_RS13675
uniprot id: R4WJF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

758793:BRPE64 RS28285
gene id: 758793:BRPE64_RS28285
uniprot id: R4X3U9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758793:BRPE64 RS10765
gene id: 758793:BRPE64_RS10765
uniprot id: R4WI39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

758793:BRPE64 RS09395
gene id: 758793:BRPE64_RS09395
uniprot id: R4WHM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

758793:BRPE64 RS11435
gene id: 758793:BRPE64_RS11435
uniprot id: R4WT31
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

758793:BRPE64 RS17885
gene id: 758793:BRPE64_RS17885
uniprot id: R4WLT9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS30695
gene id: 758793:BRPE64_RS30695
uniprot id: R4WUI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS01035
gene id: 758793:BRPE64_RS01035
uniprot id: R4WM88
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

758793:BRPE64 RS11565
gene id: 758793:BRPE64_RS11565
uniprot id: R4X012
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

758793:BRPE64 RS00510
gene id: 758793:BRPE64_RS00510
uniprot id: R4WEN2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19435
gene id: 758793:BRPE64_RS19435
uniprot id: R4WXC8
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

758793:BRPE64 RS04440
gene id: 758793:BRPE64_RS04440
uniprot id: R4WFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

758793:BRPE64 RS02005
gene id: 758793:BRPE64_RS02005
uniprot id: R4WW75
names: Similarity
messages: Belongs to the PhoH family.

758793:BRPE64 RS14665
gene id: 758793:BRPE64_RS14665
uniprot id: R4WK46
names: Similarity
messages: Belongs to the FwdC/FmdC family.

758793:BRPE64 RS19750
gene id: 758793:BRPE64_RS19750
uniprot id: R4WXF6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

758793:BRPE64 RS07285
gene id: 758793:BRPE64_RS07285
uniprot id: R4WQU2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19300
gene id: 758793:BRPE64_RS19300
uniprot id: R4WXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

758793:BRPE64 RS20530
gene id: 758793:BRPE64_RS20530
uniprot id: R4WXP3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

758793:BRPE64 RS26415
gene id: 758793:BRPE64_RS26415
uniprot id: R4X3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

758793:BRPE64 RS22955
gene id: 758793:BRPE64_RS22955
uniprot id: R4WPQ0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

758793:BRPE64 RS18180
gene id: 758793:BRPE64_RS18180
uniprot id: R4WWR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

758793:BRPE64 RS12405
gene id: 758793:BRPE64_RS12405
uniprot id: R4WTM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

758793:BRPE64 RS14840
gene id: 758793:BRPE64_RS14840
uniprot id: R4WK73
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

758793:BRPE64 RS23330
gene id: 758793:BRPE64_RS23330
uniprot id: R4WPP7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS29020
gene id: 758793:BRPE64_RS29020
uniprot id: R4X418
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS27760
gene id: 758793:BRPE64_RS27760
uniprot id: R4X4T8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19930
gene id: 758793:BRPE64_RS19930
uniprot id: R4WN05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

758793:BRPE64 RS09205
gene id: 758793:BRPE64_RS09205
uniprot id: R4WXC6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS15170
gene id: 758793:BRPE64_RS15170
uniprot id: R4WKC1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS17710
gene id: 758793:BRPE64_RS17710
uniprot id: R4WLG8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS18325
gene id: 758793:BRPE64_RS18325
uniprot id: R4WWU0
names: Similarity
messages: Belongs to the CobH/CbiC family.

758793:BRPE64 RS23735
gene id: 758793:BRPE64_RS23735
uniprot id: R4X3V6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS09935
gene id: 758793:BRPE64_RS09935
uniprot id: R4WHY7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

758793:BRPE64 RS18525
gene id: 758793:BRPE64_RS18525
uniprot id: R4WLX8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS16000
gene id: 758793:BRPE64_RS16000
uniprot id: R4WKJ4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

758793:BRPE64 RS03980
gene id: 758793:BRPE64_RS03980
uniprot id: R4WX81
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS08540
gene id: 758793:BRPE64_RS08540
uniprot id: R4WHC2
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

758793:BRPE64 RS06205
gene id: 758793:BRPE64_RS06205
uniprot id: R4WGI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

758793:BRPE64 RS09025
gene id: 758793:BRPE64_RS09025
uniprot id: R4WRQ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

758793:BRPE64 RS27515
gene id: 758793:BRPE64_RS27515
uniprot id: R4WSA2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

758793:BRPE64 RS30165
gene id: 758793:BRPE64_RS30165
uniprot id: R4WU51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

758793:BRPE64 RS16945
gene id: 758793:BRPE64_RS16945
uniprot id: R4X054
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

758793:BRPE64 RS09895
gene id: 758793:BRPE64_RS09895
uniprot id: R4WS89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

758793:BRPE64 RS16130
gene id: 758793:BRPE64_RS16130
uniprot id: R4X1L7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

758793:BRPE64 RS20255
gene id: 758793:BRPE64_RS20255
uniprot id: R4X326
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

758793:BRPE64 RS20290
gene id: 758793:BRPE64_RS20290
uniprot id: R4WN68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

758793:BRPE64 RS04850
gene id: 758793:BRPE64_RS04850
uniprot id: R4WPI2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

758793:BRPE64 RS20020
gene id: 758793:BRPE64_RS20020
uniprot id: R4WN18
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS12300
gene id: 758793:BRPE64_RS12300
uniprot id: R4WJ12
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

758793:BRPE64 RS03860
gene id: 758793:BRPE64_RS03860
uniprot id: R4WX70
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS21540
gene id: 758793:BRPE64_RS21540
uniprot id: R4WNS2
names: Similarity
messages: Belongs to the DinB family.

758793:BRPE64 RS20035
gene id: 758793:BRPE64_RS20035
uniprot id: R4WMT4
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

758793:BRPE64 RS30535
gene id: 758793:BRPE64_RS30535
uniprot id: R4WUE0
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

758793:BRPE64 RS23910
gene id: 758793:BRPE64_RS23910
uniprot id: R4WQE5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS18810
gene id: 758793:BRPE64_RS18810
uniprot id: R4X2I7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS14230
gene id: 758793:BRPE64_RS14230
uniprot id: R4WJN9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS24560
gene id: 758793:BRPE64_RS24560
uniprot id: R4WZ44
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

758793:BRPE64 RS00150
gene id: 758793:BRPE64_RS00150
uniprot id: R4WES4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS05100
gene id: 758793:BRPE64_RS05100
uniprot id: R4WGE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

758793:BRPE64 RS00105
gene id: 758793:BRPE64_RS00105
uniprot id: R4WSD1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

758793:BRPE64 RS08415
gene id: 758793:BRPE64_RS08415
uniprot id: R4WHA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758793:BRPE64 RS07075
gene id: 758793:BRPE64_RS07075
uniprot id: R4WGZ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS14670
gene id: 758793:BRPE64_RS14670
uniprot id: R4WUY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

758793:BRPE64 RS13200
gene id: 758793:BRPE64_RS13200
uniprot id: R4WJ63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

758793:BRPE64 RS20490
gene id: 758793:BRPE64_RS20490
uniprot id: R4X344
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

758793:BRPE64 RS00225
gene id: 758793:BRPE64_RS00225
uniprot id: R4WEL4
names: Similarity
messages: Belongs to the MreC family.

758793:BRPE64 RS12485
gene id: 758793:BRPE64_RS12485
uniprot id: R4X0D6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

758793:BRPE64 RS24065
gene id: 758793:BRPE64_RS24065
uniprot id: R4WQG5
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

758793:BRPE64 RS27625
gene id: 758793:BRPE64_RS27625
uniprot id: R4X087
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

758793:BRPE64 RS11090
gene id: 758793:BRPE64_RS11090
uniprot id: R4WSX0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

758793:BRPE64 RS27265
gene id: 758793:BRPE64_RS27265
uniprot id: R4X4P9
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

758793:BRPE64 RS28500
gene id: 758793:BRPE64_RS28500
uniprot id: R4X0P0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS29100
gene id: 758793:BRPE64_RS29100
uniprot id: R4WTG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS13290
gene id: 758793:BRPE64_RS13290
uniprot id: R4WYT6
names: Similarity
messages: Belongs to the TPP enzyme family.

758793:BRPE64 RS12205
gene id: 758793:BRPE64_RS12205
uniprot id: R4WIT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS08380
gene id: 758793:BRPE64_RS08380
uniprot id: R4WRD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758793:BRPE64 RS12200
gene id: 758793:BRPE64_RS12200
uniprot id: R4X0A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

758793:BRPE64 RS17670
gene id: 758793:BRPE64_RS17670
uniprot id: R4WLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

758793:BRPE64 RS12400
gene id: 758793:BRPE64_RS12400
uniprot id: R4WJ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

758793:BRPE64 RS12585
gene id: 758793:BRPE64_RS12585
uniprot id: R4WTQ5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS11430
gene id: 758793:BRPE64_RS11430
uniprot id: R4WIK2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS25085
gene id: 758793:BRPE64_RS25085
uniprot id: R4X2Z7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS10840
gene id: 758793:BRPE64_RS10840
uniprot id: R4WIB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

758793:BRPE64 RS16355
gene id: 758793:BRPE64_RS16355
uniprot id: R4WZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS03900
gene id: 758793:BRPE64_RS03900
uniprot id: R4WUG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

758793:BRPE64 RS15300
gene id: 758793:BRPE64_RS15300
uniprot id: R4X1D3
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

758793:BRPE64 RS13010
gene id: 758793:BRPE64_RS13010
uniprot id: R4WJ98
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS30825
gene id: 758793:BRPE64_RS30825
uniprot id: R4X1L2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS23515
gene id: 758793:BRPE64_RS23515
uniprot id: R4X2E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS05880
gene id: 758793:BRPE64_RS05880
uniprot id: R4WQ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS12505
gene id: 758793:BRPE64_RS12505
uniprot id: R4WYJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

758793:BRPE64 RS03380
gene id: 758793:BRPE64_RS03380
uniprot id: R4WNK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

758793:BRPE64 RS15380
gene id: 758793:BRPE64_RS15380
uniprot id: R4WZJ9
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

758793:BRPE64 RS11605
gene id: 758793:BRPE64_RS11605
uniprot id: R4WT65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

758793:BRPE64 RS02835
gene id: 758793:BRPE64_RS02835
uniprot id: R4WFP0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS03415
gene id: 758793:BRPE64_RS03415
uniprot id: R4WFL0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS04055
gene id: 758793:BRPE64_RS04055
uniprot id: R4WFS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS08010
gene id: 758793:BRPE64_RS08010
uniprot id: R4WH66
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

758793:BRPE64 RS14970
gene id: 758793:BRPE64_RS14970
uniprot id: R4X1A0
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

758793:BRPE64 RS21960
gene id: 758793:BRPE64_RS21960
uniprot id: R4WY83
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS03385
gene id: 758793:BRPE64_RS03385
uniprot id: R4WU86
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

758793:BRPE64 RS00945
gene id: 758793:BRPE64_RS00945
uniprot id: R4WVM2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

758793:BRPE64 RS19385
gene id: 758793:BRPE64_RS19385
uniprot id: R4WMS1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS21600
gene id: 758793:BRPE64_RS21600
uniprot id: R4X1S0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS22140
gene id: 758793:BRPE64_RS22140
uniprot id: R4X3H8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS02825
gene id: 758793:BRPE64_RS02825
uniprot id: R4WWT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

758793:BRPE64 RS08985
gene id: 758793:BRPE64_RS08985
uniprot id: R4WX92
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

758793:BRPE64 RS12090
gene id: 758793:BRPE64_RS12090
uniprot id: R4WTI6
names: Similarity
messages: Belongs to the BolA/IbaG family.

758793:BRPE64 RS22455
gene id: 758793:BRPE64_RS22455
uniprot id: R4X3K4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS20075
gene id: 758793:BRPE64_RS20075
uniprot id: R4X151
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS13145
gene id: 758793:BRPE64_RS13145
uniprot id: R4X0K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

758793:BRPE64 RS11610
gene id: 758793:BRPE64_RS11610
uniprot id: R4WY80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS24445
gene id: 758793:BRPE64_RS24445
uniprot id: R4WQM6
names: Similarity
messages: Belongs to the peptidase S33 family.

758793:BRPE64 RS00265
gene id: 758793:BRPE64_RS00265
uniprot id: R4WSG1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS29125
gene id: 758793:BRPE64_RS29125
uniprot id: R4WTH3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS05810
gene id: 758793:BRPE64_RS05810
uniprot id: R4WVJ9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

758793:BRPE64 RS08870
gene id: 758793:BRPE64_RS08870
uniprot id: R4WRM7
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS25700
gene id: 758793:BRPE64_RS25700
uniprot id: R4WZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

758793:BRPE64 RS19325
gene id: 758793:BRPE64_RS19325
uniprot id: R4WXB6
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

758793:BRPE64 RS07250
gene id: 758793:BRPE64_RS07250
uniprot id: R4WGZ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS04550
gene id: 758793:BRPE64_RS04550
uniprot id: R4WXF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

758793:BRPE64 RS02660
gene id: 758793:BRPE64_RS02660
uniprot id: R4WN75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS17320
gene id: 758793:BRPE64_RS17320
uniprot id: R4WLK3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758793:BRPE64 RS30870
gene id: 758793:BRPE64_RS30870
uniprot id: A0A060PGS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS10120
gene id: 758793:BRPE64_RS10120
uniprot id: R4WXP8
names: Similarity
messages: Belongs to the P(II) protein family.

758793:BRPE64 RS11345
gene id: 758793:BRPE64_RS11345
uniprot id: R4WII6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS20085
gene id: 758793:BRPE64_RS20085
uniprot id: R4WN30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

758793:BRPE64 RS13655
gene id: 758793:BRPE64_RS13655
uniprot id: R4WJK6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

758793:BRPE64 RS17655
gene id: 758793:BRPE64_RS17655
uniprot id: R4X0C9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS10445
gene id: 758793:BRPE64_RS10445
uniprot id: R4WZM3
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

758793:BRPE64 RS07460
gene id: 758793:BRPE64_RS07460
uniprot id: R4WQX2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758793:BRPE64 RS18670
gene id: 758793:BRPE64_RS18670
uniprot id: R4WM07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS12675
gene id: 758793:BRPE64_RS12675
uniprot id: R4WJ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

758793:BRPE64 RS00850
gene id: 758793:BRPE64_RS00850
uniprot id: R4WSR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

758793:BRPE64 RS25265
gene id: 758793:BRPE64_RS25265
uniprot id: R4WZB6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS12325
gene id: 758793:BRPE64_RS12325
uniprot id: R4WTL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

758793:BRPE64 RS21160
gene id: 758793:BRPE64_RS21160
uniprot id: R4WXY6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS25170
gene id: 758793:BRPE64_RS25170
uniprot id: R4WR20
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS20400
gene id: 758793:BRPE64_RS20400
uniprot id: R4X337
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS09300
gene id: 758793:BRPE64_RS09300
uniprot id: R4WXE2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS01795
gene id: 758793:BRPE64_RS01795
uniprot id: R4WT96
names: Similarity
messages: Belongs to the catalase family.

758793:BRPE64 RS09815
gene id: 758793:BRPE64_RS09815
uniprot id: R4WHX5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

758793:BRPE64 RS25315
gene id: 758793:BRPE64_RS25315
uniprot id: R4WZC5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS12500
gene id: 758793:BRPE64_RS12500
uniprot id: R4WTP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

758793:BRPE64 RS13310
gene id: 758793:BRPE64_RS13310
uniprot id: R4WU41
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

758793:BRPE64 RS28070
gene id: 758793:BRPE64_RS28070
uniprot id: R4X4W3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19565
gene id: 758793:BRPE64_RS19565
uniprot id: R4WMJ6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

758793:BRPE64 RS01570
gene id: 758793:BRPE64_RS01570
uniprot id: R4WEZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

758793:BRPE64 RS12985
gene id: 758793:BRPE64_RS12985
uniprot id: R4WJ95
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

758793:BRPE64 RS23120
gene id: 758793:BRPE64_RS23120
uniprot id: R4WYK8
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

758793:BRPE64 RS04615
gene id: 758793:BRPE64_RS04615
uniprot id: R4WXG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

758793:BRPE64 RS07490
gene id: 758793:BRPE64_RS07490
uniprot id: R4WWJ6
names: Subcellular Location Annotation
messages: Cytoplasm

758793:BRPE64 RS00520
gene id: 758793:BRPE64_RS00520
uniprot id: R4WM00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

758793:BRPE64 RS28380
gene id: 758793:BRPE64_RS28380
uniprot id: R4X0K9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS20545
gene id: 758793:BRPE64_RS20545
uniprot id: R4WN20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS17520
gene id: 758793:BRPE64_RS17520
uniprot id: R4WWC8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS25975
gene id: 758793:BRPE64_RS25975
uniprot id: R4X388
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS07255
gene id: 758793:BRPE64_RS07255
uniprot id: R4WH29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

758793:BRPE64 RS00230
gene id: 758793:BRPE64_RS00230
uniprot id: R4WET1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

758793:BRPE64 RS21645
gene id: 758793:BRPE64_RS21645
uniprot id: R4WY55
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS06230
gene id: 758793:BRPE64_RS06230
uniprot id: R4WGJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

758793:BRPE64 RS16275
gene id: 758793:BRPE64_RS16275
uniprot id: R4WZV5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

758793:BRPE64 RS23715
gene id: 758793:BRPE64_RS23715
uniprot id: R4WQ04
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS25300
gene id: 758793:BRPE64_RS25300
uniprot id: R4X482
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS14960
gene id: 758793:BRPE64_RS14960
uniprot id: R4WK90
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

758793:BRPE64 RS18645
gene id: 758793:BRPE64_RS18645
uniprot id: R4WM03
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS09515
gene id: 758793:BRPE64_RS09515
uniprot id: R4WXI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

758793:BRPE64 RS03150
gene id: 758793:BRPE64_RS03150
uniprot id: R4WNG4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

758793:BRPE64 RS21660
gene id: 758793:BRPE64_RS21660
uniprot id: R4WNU0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS00615
gene id: 758793:BRPE64_RS00615
uniprot id: R4WSM5
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

758793:BRPE64 RS29745
gene id: 758793:BRPE64_RS29745
uniprot id: R4WTQ8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS30135
gene id: 758793:BRPE64_RS30135
uniprot id: R4X5C6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

758793:BRPE64 RS09030
gene id: 758793:BRPE64_RS09030
uniprot id: R4WX99
names: Similarity
messages: Belongs to the UDPGP type 2 family.

758793:BRPE64 RS17565
gene id: 758793:BRPE64_RS17565
uniprot id: R4WLE6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS09880
gene id: 758793:BRPE64_RS09880
uniprot id: R4WZF7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS30295
gene id: 758793:BRPE64_RS30295
uniprot id: R4X4C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

758793:BRPE64 RS26205
gene id: 758793:BRPE64_RS26205
uniprot id: R4X3B3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

758793:BRPE64 RS15870
gene id: 758793:BRPE64_RS15870
uniprot id: R4WZQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

758793:BRPE64 RS19220
gene id: 758793:BRPE64_RS19220
uniprot id: R4WMP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

758793:BRPE64 RS22695
gene id: 758793:BRPE64_RS22695
uniprot id: R4WPI9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS07735
gene id: 758793:BRPE64_RS07735
uniprot id: R4WR23
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

758793:BRPE64 RS10790
gene id: 758793:BRPE64_RS10790
uniprot id: R4WIA5
names: Similarity
messages: Belongs to the UPF0434 family.

758793:BRPE64 RS26270
gene id: 758793:BRPE64_RS26270
uniprot id: R4WRV1
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

758793:BRPE64 RS21115
gene id: 758793:BRPE64_RS21115
uniprot id: R4WNF6
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

758793:BRPE64 RS04890
gene id: 758793:BRPE64_RS04890
uniprot id: R4WPJ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS12420
gene id: 758793:BRPE64_RS12420
uniprot id: R4WIV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

758793:BRPE64 RS28565
gene id: 758793:BRPE64_RS28565
uniprot id: R4WT84
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

758793:BRPE64 RS21775
gene id: 758793:BRPE64_RS21775
uniprot id: R4X1T7
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS21335
gene id: 758793:BRPE64_RS21335
uniprot id: R4WY08
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS12270
gene id: 758793:BRPE64_RS12270
uniprot id: R4WYG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

758793:BRPE64 RS11185
gene id: 758793:BRPE64_RS11185
uniprot id: R4WSY9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS16565
gene id: 758793:BRPE64_RS16565
uniprot id: R4X004
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

758793:BRPE64 RS11140
gene id: 758793:BRPE64_RS11140
uniprot id: R4WY19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

758793:BRPE64 RS11085
gene id: 758793:BRPE64_RS11085
uniprot id: R4WIF0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

758793:BRPE64 RS11645
gene id: 758793:BRPE64_RS11645
uniprot id: R4WII3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

758793:BRPE64 RS16860
gene id: 758793:BRPE64_RS16860
uniprot id: R4WLD6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

758793:BRPE64 RS05565
gene id: 758793:BRPE64_RS05565
uniprot id: R4WGA8
names: Cofactor
messages: Can also use Mn(2+) ion.

758793:BRPE64 RS00215
gene id: 758793:BRPE64_RS00215
uniprot id: R4WSF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

758793:BRPE64 RS08750
gene id: 758793:BRPE64_RS08750
uniprot id: R4WZ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

758793:BRPE64 RS16165
gene id: 758793:BRPE64_RS16165
uniprot id: R4WKM7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

758793:BRPE64 RS08400
gene id: 758793:BRPE64_RS08400
uniprot id: R4WRE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758793:BRPE64 RS22490
gene id: 758793:BRPE64_RS22490
uniprot id: R4WYD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS20065
gene id: 758793:BRPE64_RS20065
uniprot id: R4WN26
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS09280
gene id: 758793:BRPE64_RS09280
uniprot id: R4WZ80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

758793:BRPE64 RS15225
gene id: 758793:BRPE64_RS15225
uniprot id: R4WKD1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

758793:BRPE64 RS13110
gene id: 758793:BRPE64_RS13110
uniprot id: R4WU04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

758793:BRPE64 RS10850
gene id: 758793:BRPE64_RS10850
uniprot id: R4WXY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

758793:BRPE64 RS11485
gene id: 758793:BRPE64_RS11485
uniprot id: R4X002
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS07985
gene id: 758793:BRPE64_RS07985
uniprot id: R4WWU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

758793:BRPE64 RS02140
gene id: 758793:BRPE64_RS02140
uniprot id: R4WMW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758793:BRPE64 RS01800
gene id: 758793:BRPE64_RS01800
uniprot id: R4WF22
names: Similarity
messages: Belongs to the Dps family.

758793:BRPE64 RS10950
gene id: 758793:BRPE64_RS10950
uniprot id: R4WZS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

758793:BRPE64 RS02250
gene id: 758793:BRPE64_RS02250
uniprot id: R4WF90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

758793:BRPE64 RS15065
gene id: 758793:BRPE64_RS15065
uniprot id: R4X1A9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS00845
gene id: 758793:BRPE64_RS00845
uniprot id: R4WM60
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

758793:BRPE64 RS03940
gene id: 758793:BRPE64_RS03940
uniprot id: R4WFZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS10325
gene id: 758793:BRPE64_RS10325
uniprot id: R4WI35
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

758793:BRPE64 RS04845
gene id: 758793:BRPE64_RS04845
uniprot id: R4WGB3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

758793:BRPE64 RS20520
gene id: 758793:BRPE64_RS20520
uniprot id: R4WN17
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

758793:BRPE64 RS04025
gene id: 758793:BRPE64_RS04025
uniprot id: R4WX85
names: Similarity
messages: Belongs to the pirin family.

758793:BRPE64 RS07695
gene id: 758793:BRPE64_RS07695
uniprot id: R4WYN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

758793:BRPE64 RS10465
gene id: 758793:BRPE64_RS10465
uniprot id: R4WXT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS06870
gene id: 758793:BRPE64_RS06870
uniprot id: R4WQJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS06335
gene id: 758793:BRPE64_RS06335
uniprot id: R4WGS1
names: Similarity
messages: Belongs to the PhoH family.

758793:BRPE64 RS24880
gene id: 758793:BRPE64_RS24880
uniprot id: R4WQK6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

758793:BRPE64 RS26665
gene id: 758793:BRPE64_RS26665
uniprot id: R4X4J3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

758793:BRPE64 RS27160
gene id: 758793:BRPE64_RS27160
uniprot id: R4WS93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS28820
gene id: 758793:BRPE64_RS28820
uniprot id: R4WT82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

758793:BRPE64 RS23405
gene id: 758793:BRPE64_RS23405
uniprot id: R4X3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS00950
gene id: 758793:BRPE64_RS00950
uniprot id: R4WER6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

758793:BRPE64 RS31460
gene id: 758793:BRPE64_RS31460
uniprot id: A0A060PJL7
names: Similarity
messages: Belongs to the peptidase S33 family.

758793:BRPE64 RS11515
gene id: 758793:BRPE64_RS11515
uniprot id: R4X006
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS01660
gene id: 758793:BRPE64_RS01660
uniprot id: R4WMJ9
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

758793:BRPE64 RS12050
gene id: 758793:BRPE64_RS12050
uniprot id: R4WYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

758793:BRPE64 RS18785
gene id: 758793:BRPE64_RS18785
uniprot id: R4X2I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

758793:BRPE64 RS01065
gene id: 758793:BRPE64_RS01065
uniprot id: R4WVP5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

758793:BRPE64 RS27020
gene id: 758793:BRPE64_RS27020
uniprot id: R4WS65
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS30865
gene id: 758793:BRPE64_RS30865
uniprot id: A0A060PK96
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS09900
gene id: 758793:BRPE64_RS09900
uniprot id: R4WXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS30045
gene id: 758793:BRPE64_RS30045
uniprot id: R4X163
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

758793:BRPE64 RS10190
gene id: 758793:BRPE64_RS10190
uniprot id: R4WSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

758793:BRPE64 RS13360
gene id: 758793:BRPE64_RS13360
uniprot id: R4WYU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

758793:BRPE64 RS31090
gene id: 758793:BRPE64_RS31090
uniprot id: A0A060PRF6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS15930
gene id: 758793:BRPE64_RS15930
uniprot id: R4WKS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS28490
gene id: 758793:BRPE64_RS28490
uniprot id: R4WT34
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS13650
gene id: 758793:BRPE64_RS13650
uniprot id: R4WJE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

758793:BRPE64 RS07220
gene id: 758793:BRPE64_RS07220
uniprot id: R4WWF3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS09345
gene id: 758793:BRPE64_RS09345
uniprot id: R4WRY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

758793:BRPE64 RS10965
gene id: 758793:BRPE64_RS10965
uniprot id: R4WSU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS28695
gene id: 758793:BRPE64_RS28695
uniprot id: R4X514
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS06580
gene id: 758793:BRPE64_RS06580
uniprot id: R4WGN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

758793:BRPE64 RS31420
gene id: 758793:BRPE64_RS31420
uniprot id: A0A060PR26
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS29055
gene id: 758793:BRPE64_RS29055
uniprot id: R4X0U4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS30740
gene id: 758793:BRPE64_RS30740
uniprot id: R4X1J9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS26265
gene id: 758793:BRPE64_RS26265
uniprot id: R4WRL8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

758793:BRPE64 RS05485
gene id: 758793:BRPE64_RS05485
uniprot id: R4WVD8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

758793:BRPE64 RS02505
gene id: 758793:BRPE64_RS02505
uniprot id: R4WFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS27025
gene id: 758793:BRPE64_RS27025
uniprot id: R4X019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS21780
gene id: 758793:BRPE64_RS21780
uniprot id: R4X3F0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS09855
gene id: 758793:BRPE64_RS09855
uniprot id: R4WZF4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

758793:BRPE64 RS16095
gene id: 758793:BRPE64_RS16095
uniprot id: R4WKL2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS09325
gene id: 758793:BRPE64_RS09325
uniprot id: R4WXE6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS28935
gene id: 758793:BRPE64_RS28935
uniprot id: R4X527
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS21225
gene id: 758793:BRPE64_RS21225
uniprot id: R4WNI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS24185
gene id: 758793:BRPE64_RS24185
uniprot id: R4WQI1
names: Similarity
messages: Belongs to the BMP lipoprotein family.

758793:BRPE64 RS06850
gene id: 758793:BRPE64_RS06850
uniprot id: R4WW41
names: Similarity
messages: Belongs to the YciI family.

758793:BRPE64 RS31495
gene id: 758793:BRPE64_RS31495
uniprot id: A0A060PH70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS20050
gene id: 758793:BRPE64_RS20050
uniprot id: R4X148
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

758793:BRPE64 RS12385
gene id: 758793:BRPE64_RS12385
uniprot id: R4WYI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

758793:BRPE64 RS01665
gene id: 758793:BRPE64_RS01665
uniprot id: R4WT63
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

758793:BRPE64 RS02800
gene id: 758793:BRPE64_RS02800
uniprot id: R4WTY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

758793:BRPE64 RS06200
gene id: 758793:BRPE64_RS06200
uniprot id: R4WY22
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

758793:BRPE64 RS13210
gene id: 758793:BRPE64_RS13210
uniprot id: R4WU23
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

758793:BRPE64 RS11865
gene id: 758793:BRPE64_RS11865
uniprot id: R4WIS9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS03175
gene id: 758793:BRPE64_RS03175
uniprot id: R4WFS1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS24155
gene id: 758793:BRPE64_RS24155
uniprot id: R4WQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS07995
gene id: 758793:BRPE64_RS07995
uniprot id: R4WR72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS29495
gene id: 758793:BRPE64_RS29495
uniprot id: R4X458
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS11265
gene id: 758793:BRPE64_RS11265
uniprot id: R4WZX2
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

758793:BRPE64 RS10330
gene id: 758793:BRPE64_RS10330
uniprot id: R4WSH3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS15960
gene id: 758793:BRPE64_RS15960
uniprot id: R4WVK7
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

758793:BRPE64 RS03400
gene id: 758793:BRPE64_RS03400
uniprot id: R4WNK8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS25575
gene id: 758793:BRPE64_RS25575
uniprot id: R4WR15
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

758793:BRPE64 RS11270
gene id: 758793:BRPE64_RS11270
uniprot id: R4WIC2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

758793:BRPE64 RS03245
gene id: 758793:BRPE64_RS03245
uniprot id: R4WFS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

758793:BRPE64 RS21735
gene id: 758793:BRPE64_RS21735
uniprot id: R4WP20
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

758793:BRPE64 RS02680
gene id: 758793:BRPE64_RS02680
uniprot id: R4WFM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS11535
gene id: 758793:BRPE64_RS11535
uniprot id: R4WY69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

758793:BRPE64 RS17435
gene id: 758793:BRPE64_RS17435
uniprot id: R4WLC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

758793:BRPE64 RS15440
gene id: 758793:BRPE64_RS15440
uniprot id: R4WK86
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

758793:BRPE64 RS05770
gene id: 758793:BRPE64_RS05770
uniprot id: R4WXX3
names: Similarity
messages: Belongs to the skp family.

758793:BRPE64 RS27380
gene id: 758793:BRPE64_RS27380
uniprot id: R4X3L5
names: Similarity
messages: Belongs to the DSD1 family.

758793:BRPE64 RS13115
gene id: 758793:BRPE64_RS13115
uniprot id: R4WYR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

758793:BRPE64 RS17385
gene id: 758793:BRPE64_RS17385
uniprot id: R4WLC2
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

758793:BRPE64 RS23190
gene id: 758793:BRPE64_RS23190
uniprot id: R4WPL1
names: Similarity
messages: Belongs to the TPP enzyme family.

758793:BRPE64 RS10805
gene id: 758793:BRPE64_RS10805
uniprot id: R4WZR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS06615
gene id: 758793:BRPE64_RS06615
uniprot id: R4WW02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

758793:BRPE64 RS21295
gene id: 758793:BRPE64_RS21295
uniprot id: R4X3A5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS02235
gene id: 758793:BRPE64_RS02235
uniprot id: R4WMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

758793:BRPE64 RS15155
gene id: 758793:BRPE64_RS15155
uniprot id: R4WV50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS02025
gene id: 758793:BRPE64_RS02025
uniprot id: R4WTF0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS04290
gene id: 758793:BRPE64_RS04290
uniprot id: R4WXB7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS27610
gene id: 758793:BRPE64_RS27610
uniprot id: R4X4S6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

758793:BRPE64 RS29345
gene id: 758793:BRPE64_RS29345
uniprot id: R4X446
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

758793:BRPE64 RS27415
gene id: 758793:BRPE64_RS27415
uniprot id: R4WS81
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

758793:BRPE64 RS01775
gene id: 758793:BRPE64_RS01775
uniprot id: R4WT91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

758793:BRPE64 RS18300
gene id: 758793:BRPE64_RS18300
uniprot id: R4WWT5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

758793:BRPE64 RS02565
gene id: 758793:BRPE64_RS02565
uniprot id: R4WTU1
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

758793:BRPE64 RS19530
gene id: 758793:BRPE64_RS19530
uniprot id: R4X0Z8
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

758793:BRPE64 RS03115
gene id: 758793:BRPE64_RS03115
uniprot id: R4WFH7
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

758793:BRPE64 RS29240
gene id: 758793:BRPE64_RS29240
uniprot id: R4WTF8
names: Similarity
messages: Belongs to the UxaA family.

758793:BRPE64 RS03950
gene id: 758793:BRPE64_RS03950
uniprot id: R4WUH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

758793:BRPE64 RS18460
gene id: 758793:BRPE64_RS18460
uniprot id: R4X0L7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

758793:BRPE64 RS08700
gene id: 758793:BRPE64_RS08700
uniprot id: R4WZ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS01645
gene id: 758793:BRPE64_RS01645
uniprot id: R4WW03
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

758793:BRPE64 RS22405
gene id: 758793:BRPE64_RS22405
uniprot id: R4X3K0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

758793:BRPE64 RS23830
gene id: 758793:BRPE64_RS23830
uniprot id: R4WQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS30315
gene id: 758793:BRPE64_RS30315
uniprot id: R4X1A6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS16175
gene id: 758793:BRPE64_RS16175
uniprot id: R4WZU0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS06330
gene id: 758793:BRPE64_RS06330
uniprot id: R4WGK2
names: Similarity
messages: Belongs to the peptidase C40 family.

758793:BRPE64 RS29535
gene id: 758793:BRPE64_RS29535
uniprot id: R4WTP7
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS09635
gene id: 758793:BRPE64_RS09635
uniprot id: R4WXJ1
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

758793:BRPE64 RS29330
gene id: 758793:BRPE64_RS29330
uniprot id: R4WTH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

758793:BRPE64 RS02745
gene id: 758793:BRPE64_RS02745
uniprot id: R4WN92
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

758793:BRPE64 RS23070
gene id: 758793:BRPE64_RS23070
uniprot id: R4X3Q0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS11360
gene id: 758793:BRPE64_RS11360
uniprot id: R4WZY4
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

758793:BRPE64 RS31360
gene id: 758793:BRPE64_RS31360
uniprot id: A0A060PJI6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS25955
gene id: 758793:BRPE64_RS25955
uniprot id: R4WRC6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05305
gene id: 758793:BRPE64_RS05305
uniprot id: R4WPQ8
names: Similarity
messages: Belongs to the WrbA family.

758793:BRPE64 RS00260
gene id: 758793:BRPE64_RS00260
uniprot id: R4WLW0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

758793:BRPE64 RS23635
gene id: 758793:BRPE64_RS23635
uniprot id: R4X3U6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS15245
gene id: 758793:BRPE64_RS15245
uniprot id: R4WKD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

758793:BRPE64 RS26385
gene id: 758793:BRPE64_RS26385
uniprot id: R4WRX0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS09540
gene id: 758793:BRPE64_RS09540
uniprot id: R4WXI3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

758793:BRPE64 RS29365
gene id: 758793:BRPE64_RS29365
uniprot id: R4X0X8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

758793:BRPE64 RS28225
gene id: 758793:BRPE64_RS28225
uniprot id: R4WSY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

758793:BRPE64 RS09250
gene id: 758793:BRPE64_RS09250
uniprot id: R4WXD3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

758793:BRPE64 RS30200
gene id: 758793:BRPE64_RS30200
uniprot id: R4X5D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

758793:BRPE64 RS03025
gene id: 758793:BRPE64_RS03025
uniprot id: R4WNE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

758793:BRPE64 RS17365
gene id: 758793:BRPE64_RS17365
uniprot id: R4WLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

758793:BRPE64 RS19640
gene id: 758793:BRPE64_RS19640
uniprot id: R4WMV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

758793:BRPE64 RS06825
gene id: 758793:BRPE64_RS06825
uniprot id: R4WYB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS25185
gene id: 758793:BRPE64_RS25185
uniprot id: R4X471
names: Similarity
messages: Belongs to the proline racemase family.

758793:BRPE64 RS20155
gene id: 758793:BRPE64_RS20155
uniprot id: R4X319
names: Similarity
messages: Belongs to the citrate synthase family.

758793:BRPE64 RS19070
gene id: 758793:BRPE64_RS19070
uniprot id: R4X2P8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

758793:BRPE64 RS17355
gene id: 758793:BRPE64_RS17355
uniprot id: R4X096
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

758793:BRPE64 RS11375
gene id: 758793:BRPE64_RS11375
uniprot id: R4WZY7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

758793:BRPE64 RS05245
gene id: 758793:BRPE64_RS05245
uniprot id: R4WG80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

758793:BRPE64 RS24685
gene id: 758793:BRPE64_RS24685
uniprot id: R4WZ57
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

758793:BRPE64 RS18850
gene id: 758793:BRPE64_RS18850
uniprot id: R4X0Q7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS24935
gene id: 758793:BRPE64_RS24935
uniprot id: R4WQV8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS22220
gene id: 758793:BRPE64_RS22220
uniprot id: R4X1X9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758793:BRPE64 RS08855
gene id: 758793:BRPE64_RS08855
uniprot id: R4WZ22
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758793:BRPE64 RS20385
gene id: 758793:BRPE64_RS20385
uniprot id: R4WN86
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

758793:BRPE64 RS25075
gene id: 758793:BRPE64_RS25075
uniprot id: R4WQZ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS02085
gene id: 758793:BRPE64_RS02085
uniprot id: R4WFE2
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

758793:BRPE64 RS05605
gene id: 758793:BRPE64_RS05605
uniprot id: R4WXV3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS03295
gene id: 758793:BRPE64_RS03295
uniprot id: R4WFT2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

758793:BRPE64 RS01780
gene id: 758793:BRPE64_RS01780
uniprot id: R4WW25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

758793:BRPE64 RS11080
gene id: 758793:BRPE64_RS11080
uniprot id: R4WI89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

758793:BRPE64 RS07225
gene id: 758793:BRPE64_RS07225
uniprot id: R4WYI6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

758793:BRPE64 RS03260
gene id: 758793:BRPE64_RS03260
uniprot id: R4WX06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

758793:BRPE64 RS22785
gene id: 758793:BRPE64_RS22785
uniprot id: R4WPL2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS24985
gene id: 758793:BRPE64_RS24985
uniprot id: R4WZ86
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

758793:BRPE64 RS25365
gene id: 758793:BRPE64_RS25365
uniprot id: R4X329
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

758793:BRPE64 RS03340
gene id: 758793:BRPE64_RS03340
uniprot id: R4WFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

758793:BRPE64 RS14440
gene id: 758793:BRPE64_RS14440
uniprot id: R4WZA2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS12395
gene id: 758793:BRPE64_RS12395
uniprot id: R4WIV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

758793:BRPE64 RS13250
gene id: 758793:BRPE64_RS13250
uniprot id: R4WJ70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

758793:BRPE64 RS01000
gene id: 758793:BRPE64_RS01000
uniprot id: R4WES3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

758793:BRPE64 RS19785
gene id: 758793:BRPE64_RS19785
uniprot id: R4WMN3
names: Similarity
messages: Belongs to the LOG family.

758793:BRPE64 RS01590
gene id: 758793:BRPE64_RS01590
uniprot id: R4WVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS06450
gene id: 758793:BRPE64_RS06450
uniprot id: R4WY56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

758793:BRPE64 RS28655
gene id: 758793:BRPE64_RS28655
uniprot id: R4WTA0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS15775
gene id: 758793:BRPE64_RS15775
uniprot id: R4WVH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

758793:BRPE64 RS09285
gene id: 758793:BRPE64_RS09285
uniprot id: R4WHL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

758793:BRPE64 RS09985
gene id: 758793:BRPE64_RS09985
uniprot id: R4WHZ1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

758793:BRPE64 RS01790
gene id: 758793:BRPE64_RS01790
uniprot id: R4WF94
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS26085
gene id: 758793:BRPE64_RS26085
uniprot id: R4X3A4
names: Similarity
messages: Belongs to the peptidase A24 family.

758793:BRPE64 RS08030
gene id: 758793:BRPE64_RS08030
uniprot id: R4WYS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

758793:BRPE64 RS11800
gene id: 758793:BRPE64_RS11800
uniprot id: R4X036
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

758793:BRPE64 RS08585
gene id: 758793:BRPE64_RS08585
uniprot id: R4WX45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

758793:BRPE64 RS18035
gene id: 758793:BRPE64_RS18035
uniprot id: R4X0H0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS03795
gene id: 758793:BRPE64_RS03795
uniprot id: R4WFX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

758793:BRPE64 RS09410
gene id: 758793:BRPE64_RS09410
uniprot id: R4WXF8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS27045
gene id: 758793:BRPE64_RS27045
uniprot id: R4WS70
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS28075
gene id: 758793:BRPE64_RS28075
uniprot id: R4WSQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS29645
gene id: 758793:BRPE64_RS29645
uniprot id: R4X585
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS01545
gene id: 758793:BRPE64_RS01545
uniprot id: R4WEZ0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS05655
gene id: 758793:BRPE64_RS05655
uniprot id: R4WGC0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

758793:BRPE64 RS12010
gene id: 758793:BRPE64_RS12010
uniprot id: R4WIR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

758793:BRPE64 RS07715
gene id: 758793:BRPE64_RS07715
uniprot id: R4WWN7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

758793:BRPE64 RS13720
gene id: 758793:BRPE64_RS13720
uniprot id: R4X0T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

758793:BRPE64 RS13030
gene id: 758793:BRPE64_RS13030
uniprot id: R4WJA2
names: Similarity
messages: Belongs to the type III secretion exporter family.

758793:BRPE64 RS08615
gene id: 758793:BRPE64_RS08615
uniprot id: R4WHD1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

758793:BRPE64 RS10415
gene id: 758793:BRPE64_RS10415
uniprot id: R4WSJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS11590
gene id: 758793:BRPE64_RS11590
uniprot id: R4X015
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

758793:BRPE64 RS09500
gene id: 758793:BRPE64_RS09500
uniprot id: R4WZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

758793:BRPE64 RS20355
gene id: 758793:BRPE64_RS20355
uniprot id: R4X334
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758793:BRPE64 RS17260
gene id: 758793:BRPE64_RS17260
uniprot id: R4WW89
names: Similarity
messages: Belongs to the peptidase S45 family.

758793:BRPE64 RS06530
gene id: 758793:BRPE64_RS06530
uniprot id: R4WQC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

758793:BRPE64 RS24425
gene id: 758793:BRPE64_RS24425
uniprot id: R4WQM2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS14300
gene id: 758793:BRPE64_RS14300
uniprot id: R4WJV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS00255
gene id: 758793:BRPE64_RS00255
uniprot id: R4WET3
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

758793:BRPE64 RS23350
gene id: 758793:BRPE64_RS23350
uniprot id: R4X3S4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

758793:BRPE64 RS10310
gene id: 758793:BRPE64_RS10310
uniprot id: R4WXR9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS10250
gene id: 758793:BRPE64_RS10250
uniprot id: R4WZK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

758793:BRPE64 RS16885
gene id: 758793:BRPE64_RS16885
uniprot id: R4WLE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

758793:BRPE64 RS17725
gene id: 758793:BRPE64_RS17725
uniprot id: R4X0D5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS11750
gene id: 758793:BRPE64_RS11750
uniprot id: R4WY98
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

758793:BRPE64 RS07380
gene id: 758793:BRPE64_RS07380
uniprot id: R4WH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

758793:BRPE64 RS04775
gene id: 758793:BRPE64_RS04775
uniprot id: R4WV14
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

758793:BRPE64 RS26185
gene id: 758793:BRPE64_RS26185
uniprot id: R4X4G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS05495
gene id: 758793:BRPE64_RS05495
uniprot id: R4WG99
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758793:BRPE64 RS11015
gene id: 758793:BRPE64_RS11015
uniprot id: R4WSV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS20955
gene id: 758793:BRPE64_RS20955
uniprot id: R4WNB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS09535
gene id: 758793:BRPE64_RS09535
uniprot id: R4WS42
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

758793:BRPE64 RS00895
gene id: 758793:BRPE64_RS00895
uniprot id: R4WVL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS07435
gene id: 758793:BRPE64_RS07435
uniprot id: R4WQW9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

758793:BRPE64 RS04670
gene id: 758793:BRPE64_RS04670
uniprot id: R4WG01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

758793:BRPE64 RS31100
gene id: 758793:BRPE64_RS31100
uniprot id: A0A060PJD5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

758793:BRPE64 RS15160
gene id: 758793:BRPE64_RS15160
uniprot id: R4WZH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS16080
gene id: 758793:BRPE64_RS16080
uniprot id: R4WVM7
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS07785
gene id: 758793:BRPE64_RS07785
uniprot id: R4WWQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

758793:BRPE64 RS28230
gene id: 758793:BRPE64_RS28230
uniprot id: R4X0I4
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

758793:BRPE64 RS18125
gene id: 758793:BRPE64_RS18125
uniprot id: R4X2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS11490
gene id: 758793:BRPE64_RS11490
uniprot id: R4WIG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

758793:BRPE64 RS20480
gene id: 758793:BRPE64_RS20480
uniprot id: R4WXN7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS09400
gene id: 758793:BRPE64_RS09400
uniprot id: R4WHR3
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

758793:BRPE64 RS21015
gene id: 758793:BRPE64_RS21015
uniprot id: R4X387
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS29270
gene id: 758793:BRPE64_RS29270
uniprot id: R4WTJ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS14120
gene id: 758793:BRPE64_RS14120
uniprot id: R4WZ46
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

758793:BRPE64 RS09450
gene id: 758793:BRPE64_RS09450
uniprot id: R4WZ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

758793:BRPE64 RS24280
gene id: 758793:BRPE64_RS24280
uniprot id: R4WZ14
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS28595
gene id: 758793:BRPE64_RS28595
uniprot id: R4X0Q0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS27245
gene id: 758793:BRPE64_RS27245
uniprot id: R4X3K1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS01770
gene id: 758793:BRPE64_RS01770
uniprot id: R4WMM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS01555
gene id: 758793:BRPE64_RS01555
uniprot id: R4WMI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

758793:BRPE64 RS13825
gene id: 758793:BRPE64_RS13825
uniprot id: R4WUE9
names: Similarity
messages: Belongs to the leucine-binding protein family.

758793:BRPE64 RS01695
gene id: 758793:BRPE64_RS01695
uniprot id: R4WF09
names: Similarity
messages: Belongs to the AlaDH/PNT family.

758793:BRPE64 RS04455
gene id: 758793:BRPE64_RS04455
uniprot id: R4WXE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

758793:BRPE64 RS12855
gene id: 758793:BRPE64_RS12855
uniprot id: R4WYN4
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

758793:BRPE64 RS21730
gene id: 758793:BRPE64_RS21730
uniprot id: R4WNU8
names: Similarity
messages: Belongs to the GST superfamily.

758793:BRPE64 RS01975
gene id: 758793:BRPE64_RS01975
uniprot id: R4WTE0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

758793:BRPE64 RS29425
gene id: 758793:BRPE64_RS29425
uniprot id: R4X566
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS30875
gene id: 758793:BRPE64_RS30875
uniprot id: A0A060PJ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS05750
gene id: 758793:BRPE64_RS05750
uniprot id: R4WGD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

758793:BRPE64 RS11575
gene id: 758793:BRPE64_RS11575
uniprot id: R4WIM8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

758793:BRPE64 RS01995
gene id: 758793:BRPE64_RS01995
uniprot id: R4WMS9
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

758793:BRPE64 RS20570
gene id: 758793:BRPE64_RS20570
uniprot id: R4WNC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS02270
gene id: 758793:BRPE64_RS02270
uniprot id: R4WWI0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS04555
gene id: 758793:BRPE64_RS04555
uniprot id: R4WFY5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

758793:BRPE64 RS26655
gene id: 758793:BRPE64_RS26655
uniprot id: R4WZX9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS20040
gene id: 758793:BRPE64_RS20040
uniprot id: R4WN22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

758793:BRPE64 RS29800
gene id: 758793:BRPE64_RS29800
uniprot id: R4WTW2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

758793:BRPE64 RS05670
gene id: 758793:BRPE64_RS05670
uniprot id: R4WVH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

758793:BRPE64 RS28080
gene id: 758793:BRPE64_RS28080
uniprot id: R4WSV6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

758793:BRPE64 RS13125
gene id: 758793:BRPE64_RS13125
uniprot id: R4WJ53
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

758793:BRPE64 RS14820
gene id: 758793:BRPE64_RS14820
uniprot id: R4WUZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

758793:BRPE64 RS04650
gene id: 758793:BRPE64_RS04650
uniprot id: R4WG71
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

758793:BRPE64 RS09760
gene id: 758793:BRPE64_RS09760
uniprot id: R4WS69
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

758793:BRPE64 RS10910
gene id: 758793:BRPE64_RS10910
uniprot id: R4WI61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

758793:BRPE64 RS13800
gene id: 758793:BRPE64_RS13800
uniprot id: R4WJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

758793:BRPE64 RS22500
gene id: 758793:BRPE64_RS22500
uniprot id: R4X3K7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS13840
gene id: 758793:BRPE64_RS13840
uniprot id: R4WJI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

758793:BRPE64 RS13090
gene id: 758793:BRPE64_RS13090
uniprot id: R4WYR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

758793:BRPE64 RS21740
gene id: 758793:BRPE64_RS21740
uniprot id: R4WY64
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

758793:BRPE64 RS00140
gene id: 758793:BRPE64_RS00140
uniprot id: R4WSE0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

758793:BRPE64 RS05325
gene id: 758793:BRPE64_RS05325
uniprot id: R4WGG4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

758793:BRPE64 RS18520
gene id: 758793:BRPE64_RS18520
uniprot id: R4X2G1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS06185
gene id: 758793:BRPE64_RS06185
uniprot id: R4WGI4
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19015
gene id: 758793:BRPE64_RS19015
uniprot id: R4X0T0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS26600
gene id: 758793:BRPE64_RS26600
uniprot id: R4WRR8
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.

758793:BRPE64 RS26115
gene id: 758793:BRPE64_RS26115
uniprot id: R4X4F8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05465
gene id: 758793:BRPE64_RS05465
uniprot id: R4WXT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS28660
gene id: 758793:BRPE64_RS28660
uniprot id: R4X0Q8
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

758793:BRPE64 RS07850
gene id: 758793:BRPE64_RS07850
uniprot id: R4WR45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

758793:BRPE64 RS28520
gene id: 758793:BRPE64_RS28520
uniprot id: R4X3X6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19305
gene id: 758793:BRPE64_RS19305
uniprot id: R4X0X7
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

758793:BRPE64 RS02715
gene id: 758793:BRPE64_RS02715
uniprot id: R4WFM8
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

758793:BRPE64 RS11780
gene id: 758793:BRPE64_RS11780
uniprot id: R4WIK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

758793:BRPE64 RS00355
gene id: 758793:BRPE64_RS00355
uniprot id: R4WLX3
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

758793:BRPE64 RS11470
gene id: 758793:BRPE64_RS11470
uniprot id: R4WIL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS11215
gene id: 758793:BRPE64_RS11215
uniprot id: R4WY25
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

758793:BRPE64 RS04540
gene id: 758793:BRPE64_RS04540
uniprot id: R4WP79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

758793:BRPE64 RS05025
gene id: 758793:BRPE64_RS05025
uniprot id: R4WG49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

758793:BRPE64 RS24310
gene id: 758793:BRPE64_RS24310
uniprot id: R4X2P6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

758793:BRPE64 RS28350
gene id: 758793:BRPE64_RS28350
uniprot id: R4WT11
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS20615
gene id: 758793:BRPE64_RS20615
uniprot id: R4WN34
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

758793:BRPE64 RS24250
gene id: 758793:BRPE64_RS24250
uniprot id: R4WQJ3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS14735
gene id: 758793:BRPE64_RS14735
uniprot id: R4X177
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

758793:BRPE64 RS10175
gene id: 758793:BRPE64_RS10175
uniprot id: R4WZJ2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS04985
gene id: 758793:BRPE64_RS04985
uniprot id: R4WPK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

758793:BRPE64 RS31245
gene id: 758793:BRPE64_RS31245
uniprot id: A0A060PRJ4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

758793:BRPE64 RS05055
gene id: 758793:BRPE64_RS05055
uniprot id: R4WGD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

758793:BRPE64 RS24865
gene id: 758793:BRPE64_RS24865
uniprot id: R4WZ77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS17715
gene id: 758793:BRPE64_RS17715
uniprot id: R4WLQ8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

758793:BRPE64 RS16740
gene id: 758793:BRPE64_RS16740
uniprot id: R4WW15
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS02820
gene id: 758793:BRPE64_RS02820
uniprot id: R4WTY7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

758793:BRPE64 RS18795
gene id: 758793:BRPE64_RS18795
uniprot id: R4WMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

758793:BRPE64 RS15950
gene id: 758793:BRPE64_RS15950
uniprot id: R4WKI6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

758793:BRPE64 RS29090
gene id: 758793:BRPE64_RS29090
uniprot id: R4X535
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS14715
gene id: 758793:BRPE64_RS14715
uniprot id: R4WK53
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

758793:BRPE64 RS13380
gene id: 758793:BRPE64_RS13380
uniprot id: R4WU55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

758793:BRPE64 RS11585
gene id: 758793:BRPE64_RS11585
uniprot id: R4WY76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

758793:BRPE64 RS13345
gene id: 758793:BRPE64_RS13345
uniprot id: R4WJ86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

758793:BRPE64 RS08455
gene id: 758793:BRPE64_RS08455
uniprot id: R4WRE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

758793:BRPE64 RS03370
gene id: 758793:BRPE64_RS03370
uniprot id: R4WFK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

758793:BRPE64 RS02440
gene id: 758793:BRPE64_RS02440
uniprot id: R4WN40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS31145
gene id: 758793:BRPE64_RS31145
uniprot id: A0A060PJE5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS15135
gene id: 758793:BRPE64_RS15135
uniprot id: R4WV46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

758793:BRPE64 RS04325
gene id: 758793:BRPE64_RS04325
uniprot id: R4WUN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

758793:BRPE64 RS11395
gene id: 758793:BRPE64_RS11395
uniprot id: R4WZZ0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

758793:BRPE64 RS09860
gene id: 758793:BRPE64_RS09860
uniprot id: R4WHT3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19200
gene id: 758793:BRPE64_RS19200
uniprot id: R4WXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS31110
gene id: 758793:BRPE64_RS31110
uniprot id: A0A060PRG2
names: Function
names: Similarity
messages: Belongs to the nitrile hydratase subunit beta family.
messages: NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.

758793:BRPE64 RS07585
gene id: 758793:BRPE64_RS07585
uniprot id: R4WQZ7
names: Similarity
messages: Belongs to the YfgM family.

758793:BRPE64 RS07700
gene id: 758793:BRPE64_RS07700
uniprot id: R4WH28
names: Similarity
messages: Belongs to the thioredoxin family.

758793:BRPE64 RS16045
gene id: 758793:BRPE64_RS16045
uniprot id: R4X1K5
names: Similarity
messages: Belongs to the UPF0047 family.

758793:BRPE64 RS13135
gene id: 758793:BRPE64_RS13135
uniprot id: R4WU08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

758793:BRPE64 RS13075
gene id: 758793:BRPE64_RS13075
uniprot id: R4WJ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS29435
gene id: 758793:BRPE64_RS29435
uniprot id: R4WTM5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

758793:BRPE64 RS03130
gene id: 758793:BRPE64_RS03130
uniprot id: R4WU42
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

758793:BRPE64 RS01450
gene id: 758793:BRPE64_RS01450
uniprot id: R4WVX1
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

758793:BRPE64 RS10775
gene id: 758793:BRPE64_RS10775
uniprot id: R4WSR1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

758793:BRPE64 RS21370
gene id: 758793:BRPE64_RS21370
uniprot id: R4X3B2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS20145
gene id: 758793:BRPE64_RS20145
uniprot id: R4WXJ0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

758793:BRPE64 RS08390
gene id: 758793:BRPE64_RS08390
uniprot id: R4WHA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758793:BRPE64 RS26955
gene id: 758793:BRPE64_RS26955
uniprot id: R4X011
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS13315
gene id: 758793:BRPE64_RS13315
uniprot id: R4X0M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

758793:BRPE64 RS14220
gene id: 758793:BRPE64_RS14220
uniprot id: R4WZ60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS02115
gene id: 758793:BRPE64_RS02115
uniprot id: R4WMV8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

758793:BRPE64 RS16810
gene id: 758793:BRPE64_RS16810
uniprot id: R4WLC8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

758793:BRPE64 RS09610
gene id: 758793:BRPE64_RS09610
uniprot id: R4WXI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

758793:BRPE64 RS17615
gene id: 758793:BRPE64_RS17615
uniprot id: R4WLF5
names: Function
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.

758793:BRPE64 RS03835
gene id: 758793:BRPE64_RS03835
uniprot id: R4WX68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

758793:BRPE64 RS23730
gene id: 758793:BRPE64_RS23730
uniprot id: R4X2J1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

758793:BRPE64 RS10015
gene id: 758793:BRPE64_RS10015
uniprot id: R4WXN4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.

758793:BRPE64 RS09245
gene id: 758793:BRPE64_RS09245
uniprot id: R4WRW0
names: Similarity
messages: Belongs to the GppA/Ppx family.

758793:BRPE64 RS15690
gene id: 758793:BRPE64_RS15690
uniprot id: R4X1H4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS09555
gene id: 758793:BRPE64_RS09555
uniprot id: R4WHU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

758793:BRPE64 RS17080
gene id: 758793:BRPE64_RS17080
uniprot id: R4X065
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

758793:BRPE64 RS11635
gene id: 758793:BRPE64_RS11635
uniprot id: R4WY84
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS13185
gene id: 758793:BRPE64_RS13185
uniprot id: R4WU18
names: Subcellular Location Annotation
messages: Periplasm

758793:BRPE64 RS28845
gene id: 758793:BRPE64_RS28845
uniprot id: R4WTD1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS16070
gene id: 758793:BRPE64_RS16070
uniprot id: R4WKK8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS05920
gene id: 758793:BRPE64_RS05920
uniprot id: R4WGM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

758793:BRPE64 RS29945
gene id: 758793:BRPE64_RS29945
uniprot id: R4X149
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

758793:BRPE64 RS21715
gene id: 758793:BRPE64_RS21715
uniprot id: R4WY61
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05370
gene id: 758793:BRPE64_RS05370
uniprot id: R4WG89
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

758793:BRPE64 RS31140
gene id: 758793:BRPE64_RS31140
uniprot id: A0A060PGZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

758793:BRPE64 RS10785
gene id: 758793:BRPE64_RS10785
uniprot id: R4WI44
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

758793:BRPE64 RS12080
gene id: 758793:BRPE64_RS12080
uniprot id: R4X089
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

758793:BRPE64 RS24405
gene id: 758793:BRPE64_RS24405
uniprot id: R4WZ28
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

758793:BRPE64 RS26325
gene id: 758793:BRPE64_RS26325
uniprot id: R4X3B8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS30510
gene id: 758793:BRPE64_RS30510
uniprot id: R4WUD6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS20025
gene id: 758793:BRPE64_RS20025
uniprot id: R4X146
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS24415
gene id: 758793:BRPE64_RS24415
uniprot id: R4X405
names: Similarity
messages: Belongs to the proline racemase family.

758793:BRPE64 RS01650
gene id: 758793:BRPE64_RS01650
uniprot id: R4WF02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

758793:BRPE64 RS22250
gene id: 758793:BRPE64_RS22250
uniprot id: R4X3I7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

758793:BRPE64 RS23965
gene id: 758793:BRPE64_RS23965
uniprot id: R4WQF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS12315
gene id: 758793:BRPE64_RS12315
uniprot id: R4X0B7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

758793:BRPE64 RS13565
gene id: 758793:BRPE64_RS13565
uniprot id: R4WJD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

758793:BRPE64 RS04915
gene id: 758793:BRPE64_RS04915
uniprot id: R4WPJ5
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

758793:BRPE64 RS24720
gene id: 758793:BRPE64_RS24720
uniprot id: R4WQH4
names: Subcellular Location Annotation
messages: Cell inner membrane

758793:BRPE64 RS05255
gene id: 758793:BRPE64_RS05255
uniprot id: R4WPP8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS02515
gene id: 758793:BRPE64_RS02515
uniprot id: R4WTT3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

758793:BRPE64 RS01815
gene id: 758793:BRPE64_RS01815
uniprot id: R4WTA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

758793:BRPE64 RS20485
gene id: 758793:BRPE64_RS20485
uniprot id: R4X1A8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

758793:BRPE64 RS25245
gene id: 758793:BRPE64_RS25245
uniprot id: R4X318
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS03845
gene id: 758793:BRPE64_RS03845
uniprot id: R4WFY3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

758793:BRPE64 RS07975
gene id: 758793:BRPE64_RS07975
uniprot id: R4WHA7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

758793:BRPE64 RS00955
gene id: 758793:BRPE64_RS00955
uniprot id: R4WF07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

758793:BRPE64 RS17975
gene id: 758793:BRPE64_RS17975
uniprot id: R4X298
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

758793:BRPE64 RS01295
gene id: 758793:BRPE64_RS01295
uniprot id: R4WVT7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

758793:BRPE64 RS15725
gene id: 758793:BRPE64_RS15725
uniprot id: R4WVG4
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS25730
gene id: 758793:BRPE64_RS25730
uniprot id: R4X4B9
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

758793:BRPE64 RS27175
gene id: 758793:BRPE64_RS27175
uniprot id: R4X4P2
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

758793:BRPE64 RS10780
gene id: 758793:BRPE64_RS10780
uniprot id: R4WXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

758793:BRPE64 RS11850
gene id: 758793:BRPE64_RS11850
uniprot id: R4WYB6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

758793:BRPE64 RS20165
gene id: 758793:BRPE64_RS20165
uniprot id: R4WN42
names: Similarity
messages: Belongs to the PrpD family.

758793:BRPE64 RS09565
gene id: 758793:BRPE64_RS09565
uniprot id: R4WXI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

758793:BRPE64 RS05050
gene id: 758793:BRPE64_RS05050
uniprot id: R4WG52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

758793:BRPE64 RS13640
gene id: 758793:BRPE64_RS13640
uniprot id: R4WUB0
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

758793:BRPE64 RS16020
gene id: 758793:BRPE64_RS16020
uniprot id: R4WKJ8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

758793:BRPE64 RS11160
gene id: 758793:BRPE64_RS11160
uniprot id: R4WSY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

758793:BRPE64 RS30550
gene id: 758793:BRPE64_RS30550
uniprot id: R4X5G2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

758793:BRPE64 RS04645
gene id: 758793:BRPE64_RS04645
uniprot id: R4WFZ6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

758793:BRPE64 RS17665
gene id: 758793:BRPE64_RS17665
uniprot id: R4WLG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

758793:BRPE64 RS11755
gene id: 758793:BRPE64_RS11755
uniprot id: R4WIK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

758793:BRPE64 RS13160
gene id: 758793:BRPE64_RS13160
uniprot id: R4WU12
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

758793:BRPE64 RS22995
gene id: 758793:BRPE64_RS22995
uniprot id: R4WPR0
names: Cofactor
messages: Can also use Mn(2+) ion.

758793:BRPE64 RS23170
gene id: 758793:BRPE64_RS23170
uniprot id: R4WPK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

758793:BRPE64 RS04125
gene id: 758793:BRPE64_RS04125
uniprot id: R4WG11
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

758793:BRPE64 RS26865
gene id: 758793:BRPE64_RS26865
uniprot id: R4X001
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS20305
gene id: 758793:BRPE64_RS20305
uniprot id: R4X330
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

758793:BRPE64 RS05695
gene id: 758793:BRPE64_RS05695
uniprot id: R4WVH5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS13875
gene id: 758793:BRPE64_RS13875
uniprot id: R4WUF9
names: Similarity
messages: Belongs to the UPF0102 family.

758793:BRPE64 RS24220
gene id: 758793:BRPE64_RS24220
uniprot id: R4X3Y5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS06525
gene id: 758793:BRPE64_RS06525
uniprot id: R4WGU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

758793:BRPE64 RS03935
gene id: 758793:BRPE64_RS03935
uniprot id: R4WFR0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

758793:BRPE64 RS13140
gene id: 758793:BRPE64_RS13140
uniprot id: R4WYR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

758793:BRPE64 RS03145
gene id: 758793:BRPE64_RS03145
uniprot id: R4WFR8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

758793:BRPE64 RS01915
gene id: 758793:BRPE64_RS01915
uniprot id: R4WFB5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

758793:BRPE64 RS28110
gene id: 758793:BRPE64_RS28110
uniprot id: R4X0G5
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

758793:BRPE64 RS23555
gene id: 758793:BRPE64_RS23555
uniprot id: R4WYS0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

758793:BRPE64 RS00835
gene id: 758793:BRPE64_RS00835
uniprot id: R4WEQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS27615
gene id: 758793:BRPE64_RS27615
uniprot id: R4WSC8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS16075
gene id: 758793:BRPE64_RS16075
uniprot id: R4WKV7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS23605
gene id: 758793:BRPE64_RS23605
uniprot id: R4WYS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS00695
gene id: 758793:BRPE64_RS00695
uniprot id: R4WEP1
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

758793:BRPE64 RS05780
gene id: 758793:BRPE64_RS05780
uniprot id: R4WGL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

758793:BRPE64 RS14010
gene id: 758793:BRPE64_RS14010
uniprot id: R4WZ31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS31415
gene id: 758793:BRPE64_RS31415
uniprot id: A0A060PH49
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05665
gene id: 758793:BRPE64_RS05665
uniprot id: R4WPW9
names: Similarity
messages: Belongs to the ArsC family.

758793:BRPE64 RS10305
gene id: 758793:BRPE64_RS10305
uniprot id: R4WHX8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

758793:BRPE64 RS08035
gene id: 758793:BRPE64_RS08035
uniprot id: R4WH68
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

758793:BRPE64 RS15685
gene id: 758793:BRPE64_RS15685
uniprot id: R4WZN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS16485
gene id: 758793:BRPE64_RS16485
uniprot id: R4WKV0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

758793:BRPE64 RS11530
gene id: 758793:BRPE64_RS11530
uniprot id: R4WT50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

758793:BRPE64 RS25310
gene id: 758793:BRPE64_RS25310
uniprot id: R4WR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

758793:BRPE64 RS11000
gene id: 758793:BRPE64_RS11000
uniprot id: R4WZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS00115
gene id: 758793:BRPE64_RS00115
uniprot id: R4WLT5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS23600
gene id: 758793:BRPE64_RS23600
uniprot id: R4WQ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS11475
gene id: 758793:BRPE64_RS11475
uniprot id: R4WT40
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

758793:BRPE64 RS15455
gene id: 758793:BRPE64_RS15455
uniprot id: R4WZK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS05015
gene id: 758793:BRPE64_RS05015
uniprot id: R4WV57
names: Similarity
messages: Belongs to the pirin family.

758793:BRPE64 RS10090
gene id: 758793:BRPE64_RS10090
uniprot id: R4WHV3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS07495
gene id: 758793:BRPE64_RS07495
uniprot id: R4WYL6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

758793:BRPE64 RS03050
gene id: 758793:BRPE64_RS03050
uniprot id: R4WNE7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS19795
gene id: 758793:BRPE64_RS19795
uniprot id: R4WXG1
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

758793:BRPE64 RS05620
gene id: 758793:BRPE64_RS05620
uniprot id: R4WPW1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

758793:BRPE64 RS02040
gene id: 758793:BRPE64_RS02040
uniprot id: R4WMU0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS06410
gene id: 758793:BRPE64_RS06410
uniprot id: R4WVV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

758793:BRPE64 RS12790
gene id: 758793:BRPE64_RS12790
uniprot id: R4WJ07
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

758793:BRPE64 RS03915
gene id: 758793:BRPE64_RS03915
uniprot id: R4WFZ2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

758793:BRPE64 RS03675
gene id: 758793:BRPE64_RS03675
uniprot id: R4WNP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

758793:BRPE64 RS17740
gene id: 758793:BRPE64_RS17740
uniprot id: R4WLR3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

758793:BRPE64 RS20105
gene id: 758793:BRPE64_RS20105
uniprot id: R4WMU7
names: Similarity
messages: Belongs to the citrate synthase family.

758793:BRPE64 RS13880
gene id: 758793:BRPE64_RS13880
uniprot id: R4WZ13
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

758793:BRPE64 RS30920
gene id: 758793:BRPE64_RS30920
uniprot id: A0A060PQR0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS03170
gene id: 758793:BRPE64_RS03170
uniprot id: R4WFI1
names: Subcellular Location Annotation
messages: Cell outer membrane

758793:BRPE64 RS24945
gene id: 758793:BRPE64_RS24945
uniprot id: R4X2Y0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758793:BRPE64 RS21565
gene id: 758793:BRPE64_RS21565
uniprot id: R4WNS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS00420
gene id: 758793:BRPE64_RS00420
uniprot id: R4WLY5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

758793:BRPE64 RS25055
gene id: 758793:BRPE64_RS25055
uniprot id: R4WZ92
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS12040
gene id: 758793:BRPE64_RS12040
uniprot id: R4WIX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS25970
gene id: 758793:BRPE64_RS25970
uniprot id: R4WZP0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS04825
gene id: 758793:BRPE64_RS04825
uniprot id: R4WG29
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

758793:BRPE64 RS23260
gene id: 758793:BRPE64_RS23260
uniprot id: R4WPY0
names: Similarity
messages: Belongs to the DapA family.

758793:BRPE64 RS27155
gene id: 758793:BRPE64_RS27155
uniprot id: R4WS30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS00135
gene id: 758793:BRPE64_RS00135
uniprot id: R4WLT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

758793:BRPE64 RS09755
gene id: 758793:BRPE64_RS09755
uniprot id: R4WHW8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

758793:BRPE64 RS33780
gene id: 758793:BRPE64_RS33780
uniprot id: R4X3N6
names: Similarity
messages: Belongs to the VgrG protein family.

758793:BRPE64 RS06290
gene id: 758793:BRPE64_RS06290
uniprot id: R4WQ75
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

758793:BRPE64 RS09600
gene id: 758793:BRPE64_RS09600
uniprot id: R4WHQ9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

758793:BRPE64 RS04530
gene id: 758793:BRPE64_RS04530
uniprot id: R4WFY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

758793:BRPE64 RS15290
gene id: 758793:BRPE64_RS15290
uniprot id: R4WV79
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

758793:BRPE64 RS19515
gene id: 758793:BRPE64_RS19515
uniprot id: R4WMI8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

758793:BRPE64 RS19405
gene id: 758793:BRPE64_RS19405
uniprot id: R4WMH5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS11855
gene id: 758793:BRPE64_RS11855
uniprot id: R4X045
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

758793:BRPE64 RS10960
gene id: 758793:BRPE64_RS10960
uniprot id: R4WID0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS21345
gene id: 758793:BRPE64_RS21345
uniprot id: R4X3B0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS25580
gene id: 758793:BRPE64_RS25580
uniprot id: R4WRC9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS31510
gene id: 758793:BRPE64_RS31510
uniprot id: A0A060PRR1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS12445
gene id: 758793:BRPE64_RS12445
uniprot id: R4WIW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

758793:BRPE64 RS05545
gene id: 758793:BRPE64_RS05545
uniprot id: R4WGI7
names: Similarity
messages: Belongs to the malate synthase family.

758793:BRPE64 RS02135
gene id: 758793:BRPE64_RS02135
uniprot id: R4WFE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

758793:BRPE64 RS30705
gene id: 758793:BRPE64_RS30705
uniprot id: R4X4G0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS24860
gene id: 758793:BRPE64_RS24860
uniprot id: R4WQU3
names: Similarity
messages: Belongs to the YkuD family.

758793:BRPE64 RS00525
gene id: 758793:BRPE64_RS00525
uniprot id: R4WSK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

758793:BRPE64 RS29310
gene id: 758793:BRPE64_RS29310
uniprot id: R4WTK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS03315
gene id: 758793:BRPE64_RS03315
uniprot id: R4WFJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

758793:BRPE64 RS14430
gene id: 758793:BRPE64_RS14430
uniprot id: R4WK10
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

758793:BRPE64 RS25355
gene id: 758793:BRPE64_RS25355
uniprot id: R4WR69
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS02345
gene id: 758793:BRPE64_RS02345
uniprot id: R4WFJ2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

758793:BRPE64 RS10895
gene id: 758793:BRPE64_RS10895
uniprot id: R4WST5
names: Similarity
messages: Belongs to the pirin family.

758793:BRPE64 RS12770
gene id: 758793:BRPE64_RS12770
uniprot id: R4WJ65
names: Similarity
messages: Belongs to the ArsC family.

758793:BRPE64 RS18840
gene id: 758793:BRPE64_RS18840
uniprot id: R4WMC1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS03330
gene id: 758793:BRPE64_RS03330
uniprot id: R4WU77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS06420
gene id: 758793:BRPE64_RS06420
uniprot id: R4WVW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

758793:BRPE64 RS04565
gene id: 758793:BRPE64_RS04565
uniprot id: R4WUU8
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

758793:BRPE64 RS09480
gene id: 758793:BRPE64_RS09480
uniprot id: R4WHN4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

758793:BRPE64 RS19320
gene id: 758793:BRPE64_RS19320
uniprot id: R4WMQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

758793:BRPE64 RS15265
gene id: 758793:BRPE64_RS15265
uniprot id: R4WV74
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

758793:BRPE64 RS24175
gene id: 758793:BRPE64_RS24175
uniprot id: R4X3Y2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS08135
gene id: 758793:BRPE64_RS08135
uniprot id: R4WH77
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

758793:BRPE64 RS22920
gene id: 758793:BRPE64_RS22920
uniprot id: R4X269
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

758793:BRPE64 RS10170
gene id: 758793:BRPE64_RS10170
uniprot id: R4WXQ3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS29790
gene id: 758793:BRPE64_RS29790
uniprot id: R4X597
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS12165
gene id: 758793:BRPE64_RS12165
uniprot id: R4WTJ5
names: Similarity
messages: Belongs to the glutamate synthase family.

758793:BRPE64 RS15490
gene id: 758793:BRPE64_RS15490
uniprot id: R4WK95
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS07730
gene id: 758793:BRPE64_RS07730
uniprot id: R4WH78
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

758793:BRPE64 RS20335
gene id: 758793:BRPE64_RS20335
uniprot id: R4WMY8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05275
gene id: 758793:BRPE64_RS05275
uniprot id: R4WGF9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS08815
gene id: 758793:BRPE64_RS08815
uniprot id: R4WHJ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS08005
gene id: 758793:BRPE64_RS08005
uniprot id: R4WYS4
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS30190
gene id: 758793:BRPE64_RS30190
uniprot id: R4WU56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

758793:BRPE64 RS24045
gene id: 758793:BRPE64_RS24045
uniprot id: R4WYZ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS03865
gene id: 758793:BRPE64_RS03865
uniprot id: R4WFQ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS04015
gene id: 758793:BRPE64_RS04015
uniprot id: R4WNV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

758793:BRPE64 RS08440
gene id: 758793:BRPE64_RS08440
uniprot id: R4WYW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

758793:BRPE64 RS16655
gene id: 758793:BRPE64_RS16655
uniprot id: R4X013
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS09790
gene id: 758793:BRPE64_RS09790
uniprot id: R4WZE7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

758793:BRPE64 RS30860
gene id: 758793:BRPE64_RS30860
uniprot id: A0A060PR90
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS10425
gene id: 758793:BRPE64_RS10425
uniprot id: R4WZM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

758793:BRPE64 RS01100
gene id: 758793:BRPE64_RS01100
uniprot id: R4WF21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS10245
gene id: 758793:BRPE64_RS10245
uniprot id: R4WXR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

758793:BRPE64 RS20435
gene id: 758793:BRPE64_RS20435
uniprot id: R4WXN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS13685
gene id: 758793:BRPE64_RS13685
uniprot id: R4WUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS19170
gene id: 758793:BRPE64_RS19170
uniprot id: R4WMD9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

758793:BRPE64 RS03350
gene id: 758793:BRPE64_RS03350
uniprot id: R4WU82
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS01805
gene id: 758793:BRPE64_RS01805
uniprot id: R4WF96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

758793:BRPE64 RS02000
gene id: 758793:BRPE64_RS02000
uniprot id: R4WTE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

758793:BRPE64 RS12435
gene id: 758793:BRPE64_RS12435
uniprot id: R4WYI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

758793:BRPE64 RS11715
gene id: 758793:BRPE64_RS11715
uniprot id: R4WIP7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758793:BRPE64 RS29815
gene id: 758793:BRPE64_RS29815
uniprot id: R4WTS7
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

758793:BRPE64 RS02760
gene id: 758793:BRPE64_RS02760
uniprot id: R4WFE6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

758793:BRPE64 RS04120
gene id: 758793:BRPE64_RS04120
uniprot id: R4WFT1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS26430
gene id: 758793:BRPE64_RS26430
uniprot id: R4WRX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

758793:BRPE64 RS27320
gene id: 758793:BRPE64_RS27320
uniprot id: R4WSD2
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

758793:BRPE64 RS03665
gene id: 758793:BRPE64_RS03665
uniprot id: R4WFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

758793:BRPE64 RS20180
gene id: 758793:BRPE64_RS20180
uniprot id: R4X321
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS15585
gene id: 758793:BRPE64_RS15585
uniprot id: R4WKK1
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

758793:BRPE64 RS22225
gene id: 758793:BRPE64_RS22225
uniprot id: R4X3I5
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

758793:BRPE64 RS27460
gene id: 758793:BRPE64_RS27460
uniprot id: R4X4R4
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS10220
gene id: 758793:BRPE64_RS10220
uniprot id: R4WXQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS21510
gene id: 758793:BRPE64_RS21510
uniprot id: R4X3D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS21145
gene id: 758793:BRPE64_RS21145
uniprot id: R4X395
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS21020
gene id: 758793:BRPE64_RS21020
uniprot id: R4WND3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

758793:BRPE64 RS17620
gene id: 758793:BRPE64_RS17620
uniprot id: R4WLP5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

758793:BRPE64 RS12490
gene id: 758793:BRPE64_RS12490
uniprot id: R4WIW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

758793:BRPE64 RS22525
gene id: 758793:BRPE64_RS22525
uniprot id: R4X3K9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS15790
gene id: 758793:BRPE64_RS15790
uniprot id: R4WKF2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

758793:BRPE64 RS21425
gene id: 758793:BRPE64_RS21425
uniprot id: R4WNQ4
names: Subcellular Location Annotation
messages: Cytoplasm

758793:BRPE64 RS00315
gene id: 758793:BRPE64_RS00315
uniprot id: R4WSH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

758793:BRPE64 RS01390
gene id: 758793:BRPE64_RS01390
uniprot id: R4WEX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

758793:BRPE64 RS11560
gene id: 758793:BRPE64_RS11560
uniprot id: R4WY73
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

758793:BRPE64 RS11415
gene id: 758793:BRPE64_RS11415
uniprot id: R4WY51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

758793:BRPE64 RS25320
gene id: 758793:BRPE64_RS25320
uniprot id: R4X325
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS24090
gene id: 758793:BRPE64_RS24090
uniprot id: R4WYZ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS21435
gene id: 758793:BRPE64_RS21435
uniprot id: R4WY34
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS08175
gene id: 758793:BRPE64_RS08175
uniprot id: R4WYU1
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

758793:BRPE64 RS05500
gene id: 758793:BRPE64_RS05500
uniprot id: R4WGI1
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family.

758793:BRPE64 RS11190
gene id: 758793:BRPE64_RS11190
uniprot id: R4WY23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

758793:BRPE64 RS22450
gene id: 758793:BRPE64_RS22450
uniprot id: R4X209
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

758793:BRPE64 RS21505
gene id: 758793:BRPE64_RS21505
uniprot id: R4X317
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

758793:BRPE64 RS10225
gene id: 758793:BRPE64_RS10225
uniprot id: R4WZJ7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS26650
gene id: 758793:BRPE64_RS26650
uniprot id: R4WS09
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

758793:BRPE64 RS11385
gene id: 758793:BRPE64_RS11385
uniprot id: R4WIJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

758793:BRPE64 RS23380
gene id: 758793:BRPE64_RS23380
uniprot id: R4WPQ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS10520
gene id: 758793:BRPE64_RS10520
uniprot id: R4WXU5
names: Subcellular Location Annotation
messages: Periplasm

758793:BRPE64 RS09290
gene id: 758793:BRPE64_RS09290
uniprot id: R4WHQ1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

758793:BRPE64 RS09830
gene id: 758793:BRPE64_RS09830
uniprot id: R4WZF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

758793:BRPE64 RS01290
gene id: 758793:BRPE64_RS01290
uniprot id: R4WSZ7
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS11130
gene id: 758793:BRPE64_RS11130
uniprot id: R4WIF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

758793:BRPE64 RS29025
gene id: 758793:BRPE64_RS29025
uniprot id: R4X532
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

758793:BRPE64 RS07660
gene id: 758793:BRPE64_RS07660
uniprot id: R4WR10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS24545
gene id: 758793:BRPE64_RS24545
uniprot id: R4X417
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS12365
gene id: 758793:BRPE64_RS12365
uniprot id: R4X0C2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

758793:BRPE64 RS31880
gene id: 758793:BRPE64_RS31880
uniprot id: R4WSF9
names: Similarity
messages: Belongs to the VgrG protein family.

758793:BRPE64 RS03680
gene id: 758793:BRPE64_RS03680
uniprot id: R4WX52
names: Similarity
messages: Belongs to the YicC/YloC family.

758793:BRPE64 RS03320
gene id: 758793:BRPE64_RS03320
uniprot id: R4WFT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

758793:BRPE64 RS05960
gene id: 758793:BRPE64_RS05960
uniprot id: R4WXZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

758793:BRPE64 RS18415
gene id: 758793:BRPE64_RS18415
uniprot id: R4X0L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

758793:BRPE64 RS11625
gene id: 758793:BRPE64_RS11625
uniprot id: R4WIN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS12825
gene id: 758793:BRPE64_RS12825
uniprot id: R4WTV1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

758793:BRPE64 RS08370
gene id: 758793:BRPE64_RS08370
uniprot id: R4WHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

758793:BRPE64 RS00635
gene id: 758793:BRPE64_RS00635
uniprot id: R4WM20
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

758793:BRPE64 RS21165
gene id: 758793:BRPE64_RS21165
uniprot id: R4X1J6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

758793:BRPE64 RS12370
gene id: 758793:BRPE64_RS12370
uniprot id: R4WIV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

758793:BRPE64 RS21030
gene id: 758793:BRPE64_RS21030
uniprot id: R4X1I1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

758793:BRPE64 RS05970
gene id: 758793:BRPE64_RS05970
uniprot id: R4WQ16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS12530
gene id: 758793:BRPE64_RS12530
uniprot id: R4WTP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

758793:BRPE64 RS26920
gene id: 758793:BRPE64_RS26920
uniprot id: R4X3H0
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

758793:BRPE64 RS11870
gene id: 758793:BRPE64_RS11870
uniprot id: R4WTD2
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

758793:BRPE64 RS05020
gene id: 758793:BRPE64_RS05020
uniprot id: R4WXN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS20055
gene id: 758793:BRPE64_RS20055
uniprot id: R4X310
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

758793:BRPE64 RS11860
gene id: 758793:BRPE64_RS11860
uniprot id: R4WIM2
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

758793:BRPE64 RS25485
gene id: 758793:BRPE64_RS25485
uniprot id: R4WRA5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS06535
gene id: 758793:BRPE64_RS06535
uniprot id: R4WVY8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

758793:BRPE64 RS27825
gene id: 758793:BRPE64_RS27825
uniprot id: R4X4U4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS12655
gene id: 758793:BRPE64_RS12655
uniprot id: R4WJ51
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS21400
gene id: 758793:BRPE64_RS21400
uniprot id: R4WNP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

758793:BRPE64 RS11195
gene id: 758793:BRPE64_RS11195
uniprot id: R4WZW2
names: Similarity
messages: Belongs to the allantoicase family.

758793:BRPE64 RS17625
gene id: 758793:BRPE64_RS17625
uniprot id: R4WWE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic amine dehydrogenase heavy chain family.
messages: Periplasm

758793:BRPE64 RS23895
gene id: 758793:BRPE64_RS23895
uniprot id: R4X2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS28930
gene id: 758793:BRPE64_RS28930
uniprot id: R4X410
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS15485
gene id: 758793:BRPE64_RS15485
uniprot id: R4X1F1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS30290
gene id: 758793:BRPE64_RS30290
uniprot id: R4X1A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

758793:BRPE64 RS14170
gene id: 758793:BRPE64_RS14170
uniprot id: R4WZ53
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS29410
gene id: 758793:BRPE64_RS29410
uniprot id: R4WTL9
names: Similarity
messages: Belongs to the pyruvate kinase family.

758793:BRPE64 RS23325
gene id: 758793:BRPE64_RS23325
uniprot id: R4X3S2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

758793:BRPE64 RS10815
gene id: 758793:BRPE64_RS10815
uniprot id: R4WIA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

758793:BRPE64 RS27270
gene id: 758793:BRPE64_RS27270
uniprot id: R4WS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS02365
gene id: 758793:BRPE64_RS02365
uniprot id: R4WFJ4
names: Similarity
messages: Belongs to the peptidase S13 family.

758793:BRPE64 RS29290
gene id: 758793:BRPE64_RS29290
uniprot id: R4WTJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

758793:BRPE64 RS07970
gene id: 758793:BRPE64_RS07970
uniprot id: R4WH60
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

758793:BRPE64 RS20090
gene id: 758793:BRPE64_RS20090
uniprot id: R4WXI5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

758793:BRPE64 RS18820
gene id: 758793:BRPE64_RS18820
uniprot id: R4WMB5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS20080
gene id: 758793:BRPE64_RS20080
uniprot id: R4WMU2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS03810
gene id: 758793:BRPE64_RS03810
uniprot id: R4WX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

758793:BRPE64 RS09620
gene id: 758793:BRPE64_RS09620
uniprot id: R4WHR1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

758793:BRPE64 RS15240
gene id: 758793:BRPE64_RS15240
uniprot id: R4WK47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

758793:BRPE64 RS20450
gene id: 758793:BRPE64_RS20450
uniprot id: R4WN06
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS10625
gene id: 758793:BRPE64_RS10625
uniprot id: R4WZP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

758793:BRPE64 RS00625
gene id: 758793:BRPE64_RS00625
uniprot id: R4WEN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

758793:BRPE64 RS04885
gene id: 758793:BRPE64_RS04885
uniprot id: R4WGB8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

758793:BRPE64 RS02520
gene id: 758793:BRPE64_RS02520
uniprot id: R4WWM5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS04030
gene id: 758793:BRPE64_RS04030
uniprot id: R4WFS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

758793:BRPE64 RS01380
gene id: 758793:BRPE64_RS01380
uniprot id: R4WT13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS16320
gene id: 758793:BRPE64_RS16320
uniprot id: R4WKR0
names: Function
names: Subcellular Location Annotation
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane

758793:BRPE64 RS23755
gene id: 758793:BRPE64_RS23755
uniprot id: R4X3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS30720
gene id: 758793:BRPE64_RS30720
uniprot id: R4X4H0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758793:BRPE64 RS11785
gene id: 758793:BRPE64_RS11785
uniprot id: R4WIQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

758793:BRPE64 RS04520
gene id: 758793:BRPE64_RS04520
uniprot id: R4WUT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

758793:BRPE64 RS17985
gene id: 758793:BRPE64_RS17985
uniprot id: R4WWL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

758793:BRPE64 RS07775
gene id: 758793:BRPE64_RS07775
uniprot id: R4WH84
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

758793:BRPE64 RS13285
gene id: 758793:BRPE64_RS13285
uniprot id: R4WJE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

758793:BRPE64 RS11305
gene id: 758793:BRPE64_RS11305
uniprot id: R4WT09
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS17575
gene id: 758793:BRPE64_RS17575
uniprot id: R4WWD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS31065
gene id: 758793:BRPE64_RS31065
uniprot id: A0A060PRE9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS03770
gene id: 758793:BRPE64_RS03770
uniprot id: R4WFX5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

758793:BRPE64 RS12980
gene id: 758793:BRPE64_RS12980
uniprot id: R4WJ33
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

758793:BRPE64 RS22575
gene id: 758793:BRPE64_RS22575
uniprot id: R4X3L2
names: Similarity
messages: Belongs to the IlvD/Edd family.

758793:BRPE64 RS02815
gene id: 758793:BRPE64_RS02815
uniprot id: R4WNA4
names: Similarity
messages: Belongs to the UPF0758 family.

758793:BRPE64 RS28375
gene id: 758793:BRPE64_RS28375
uniprot id: R4WT18
names: Similarity
messages: Belongs to the DapA family.

758793:BRPE64 RS03195
gene id: 758793:BRPE64_RS03195
uniprot id: R4WFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

758793:BRPE64 RS27230
gene id: 758793:BRPE64_RS27230
uniprot id: R4WS39
names: Similarity
messages: Belongs to the UPF0178 family.

758793:BRPE64 RS05425
gene id: 758793:BRPE64_RS05425
uniprot id: R4WGH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

758793:BRPE64 RS12440
gene id: 758793:BRPE64_RS12440
uniprot id: R4X0D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

758793:BRPE64 RS31055
gene id: 758793:BRPE64_RS31055
uniprot id: A0A060PJC7
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS03685
gene id: 758793:BRPE64_RS03685
uniprot id: R4WFN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

758793:BRPE64 RS03120
gene id: 758793:BRPE64_RS03120
uniprot id: R4WFR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

758793:BRPE64 RS15760
gene id: 758793:BRPE64_RS15760
uniprot id: R4X1I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

758793:BRPE64 RS31650
gene id: 758793:BRPE64_RS31650
uniprot id: A0A060PR93
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS21170
gene id: 758793:BRPE64_RS21170
uniprot id: R4X396
names: Similarity
messages: Belongs to the TPP enzyme family.

758793:BRPE64 RS23760
gene id: 758793:BRPE64_RS23760
uniprot id: R4WQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS09575
gene id: 758793:BRPE64_RS09575
uniprot id: R4WHQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

758793:BRPE64 RS09075
gene id: 758793:BRPE64_RS09075
uniprot id: R4WRR9
names: Similarity
messages: Belongs to the TPP enzyme family.

758793:BRPE64 RS04965
gene id: 758793:BRPE64_RS04965
uniprot id: R4WV48
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

758793:BRPE64 RS29420
gene id: 758793:BRPE64_RS29420
uniprot id: R4X452
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS04595
gene id: 758793:BRPE64_RS04595
uniprot id: R4WXG4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS28060
gene id: 758793:BRPE64_RS28060
uniprot id: R4X0F7
names: Similarity
messages: Belongs to the peptidase S11 family.

758793:BRPE64 RS14055
gene id: 758793:BRPE64_RS14055
uniprot id: R4WJL2
names: Similarity
messages: Belongs to the ParB family.

758793:BRPE64 RS04400
gene id: 758793:BRPE64_RS04400
uniprot id: R4WXD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

758793:BRPE64 RS26025
gene id: 758793:BRPE64_RS26025
uniprot id: R4X4E9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

758793:BRPE64 RS01125
gene id: 758793:BRPE64_RS01125
uniprot id: R4WF23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

758793:BRPE64 RS28670
gene id: 758793:BRPE64_RS28670
uniprot id: R4X513
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS12045
gene id: 758793:BRPE64_RS12045
uniprot id: R4WTH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

758793:BRPE64 RS02325
gene id: 758793:BRPE64_RS02325
uniprot id: R4WN24
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758793:BRPE64 RS11010
gene id: 758793:BRPE64_RS11010
uniprot id: R4WID8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS13305
gene id: 758793:BRPE64_RS13305
uniprot id: R4WJE7
names: Similarity
messages: Belongs to the leucine-binding protein family.

758793:BRPE64 RS31295
gene id: 758793:BRPE64_RS31295
uniprot id: A0A060PRK6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS17200
gene id: 758793:BRPE64_RS17200
uniprot id: R4X078
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS14115
gene id: 758793:BRPE64_RS14115
uniprot id: R4WUJ5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS17905
gene id: 758793:BRPE64_RS17905
uniprot id: R4WLK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS18855
gene id: 758793:BRPE64_RS18855
uniprot id: R4X2J3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

758793:BRPE64 RS03805
gene id: 758793:BRPE64_RS03805
uniprot id: R4WUE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

758793:BRPE64 RS08230
gene id: 758793:BRPE64_RS08230
uniprot id: R4WHD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

758793:BRPE64 RS07345
gene id: 758793:BRPE64_RS07345
uniprot id: R4WYJ9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS17650
gene id: 758793:BRPE64_RS17650
uniprot id: R4WWE8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS01010
gene id: 758793:BRPE64_RS01010
uniprot id: R4WM85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS05240
gene id: 758793:BRPE64_RS05240
uniprot id: R4WXQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

758793:BRPE64 RS08830
gene id: 758793:BRPE64_RS08830
uniprot id: R4WZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

758793:BRPE64 RS22330
gene id: 758793:BRPE64_RS22330
uniprot id: R4WYB9
names: Similarity
messages: Belongs to the TPP enzyme family.

758793:BRPE64 RS23360
gene id: 758793:BRPE64_RS23360
uniprot id: R4WPZ7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS07905
gene id: 758793:BRPE64_RS07905
uniprot id: R4WWS6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS20890
gene id: 758793:BRPE64_RS20890
uniprot id: R4WXU6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS11240
gene id: 758793:BRPE64_RS11240
uniprot id: R4WZW8
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

758793:BRPE64 RS21630
gene id: 758793:BRPE64_RS21630
uniprot id: R4X3E0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS01275
gene id: 758793:BRPE64_RS01275
uniprot id: R4WEV5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

758793:BRPE64 RS23090
gene id: 758793:BRPE64_RS23090
uniprot id: R4X294
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

758793:BRPE64 RS09475
gene id: 758793:BRPE64_RS09475
uniprot id: R4WZ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

758793:BRPE64 RS01020
gene id: 758793:BRPE64_RS01020
uniprot id: R4WVN6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS02805
gene id: 758793:BRPE64_RS02805
uniprot id: R4WFF1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

758793:BRPE64 RS03065
gene id: 758793:BRPE64_RS03065
uniprot id: R4WFH3
names: Subcellular Location Annotation
messages: Nucleus

758793:BRPE64 RS26720
gene id: 758793:BRPE64_RS26720
uniprot id: R4WS20
names: Caution
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS12075
gene id: 758793:BRPE64_RS12075
uniprot id: R4WYF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

758793:BRPE64 RS10585
gene id: 758793:BRPE64_RS10585
uniprot id: R4WI71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

758793:BRPE64 RS20015
gene id: 758793:BRPE64_RS20015
uniprot id: R4WMT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

758793:BRPE64 RS21850
gene id: 758793:BRPE64_RS21850
uniprot id: R4WNW3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS21365
gene id: 758793:BRPE64_RS21365
uniprot id: R4X1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS15895
gene id: 758793:BRPE64_RS15895
uniprot id: R4WZQ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS31500
gene id: 758793:BRPE64_RS31500
uniprot id: A0A060PJN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS04480
gene id: 758793:BRPE64_RS04480
uniprot id: R4WFX7
names: Subcellular Location Annotation
messages: Cytoplasm

758793:BRPE64 RS07325
gene id: 758793:BRPE64_RS07325
uniprot id: R4WH02
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

758793:BRPE64 RS29300
gene id: 758793:BRPE64_RS29300
uniprot id: R4X555
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS04500
gene id: 758793:BRPE64_RS04500
uniprot id: R4WXF1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS04525
gene id: 758793:BRPE64_RS04525
uniprot id: R4WXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

758793:BRPE64 RS20115
gene id: 758793:BRPE64_RS20115
uniprot id: R4WNR9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

758793:BRPE64 RS02240
gene id: 758793:BRPE64_RS02240
uniprot id: R4WTL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

758793:BRPE64 RS05410
gene id: 758793:BRPE64_RS05410
uniprot id: R4WVC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

758793:BRPE64 RS11150
gene id: 758793:BRPE64_RS11150
uniprot id: R4WIA3
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

758793:BRPE64 RS12070
gene id: 758793:BRPE64_RS12070
uniprot id: R4WTI3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

758793:BRPE64 RS21685
gene id: 758793:BRPE64_RS21685
uniprot id: R4WNU2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS28400
gene id: 758793:BRPE64_RS28400
uniprot id: R4WT22
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS19995
gene id: 758793:BRPE64_RS19995
uniprot id: R4WN15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS25380
gene id: 758793:BRPE64_RS25380
uniprot id: R4WZD7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

758793:BRPE64 RS02765
gene id: 758793:BRPE64_RS02765
uniprot id: R4WFN2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

758793:BRPE64 RS13370
gene id: 758793:BRPE64_RS13370
uniprot id: R4WJ91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

758793:BRPE64 RS10210
gene id: 758793:BRPE64_RS10210
uniprot id: R4WI23
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

758793:BRPE64 RS20120
gene id: 758793:BRPE64_RS20120
uniprot id: R4X3D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS00435
gene id: 758793:BRPE64_RS00435
uniprot id: R4WEM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS13695
gene id: 758793:BRPE64_RS13695
uniprot id: R4X0S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

758793:BRPE64 RS02685
gene id: 758793:BRPE64_RS02685
uniprot id: R4WN80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS22775
gene id: 758793:BRPE64_RS22775
uniprot id: R4X3M9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS21325
gene id: 758793:BRPE64_RS21325
uniprot id: R4WNK6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS10480
gene id: 758793:BRPE64_RS10480
uniprot id: R4WI55
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS13555
gene id: 758793:BRPE64_RS13555
uniprot id: R4WYW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

758793:BRPE64 RS28065
gene id: 758793:BRPE64_RS28065
uniprot id: R4X3T0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS00285
gene id: 758793:BRPE64_RS00285
uniprot id: R4WLW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

758793:BRPE64 RS00310
gene id: 758793:BRPE64_RS00310
uniprot id: R4WLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

758793:BRPE64 RS08610
gene id: 758793:BRPE64_RS08610
uniprot id: R4WYY7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

758793:BRPE64 RS13745
gene id: 758793:BRPE64_RS13745
uniprot id: R4WJG4
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS26445
gene id: 758793:BRPE64_RS26445
uniprot id: R4X4H6
names: Similarity
messages: Belongs to the UPF0502 family.

758793:BRPE64 RS29755
gene id: 758793:BRPE64_RS29755
uniprot id: R4X127
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS24705
gene id: 758793:BRPE64_RS24705
uniprot id: R4WZ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

758793:BRPE64 RS09100
gene id: 758793:BRPE64_RS09100
uniprot id: R4WRS6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS22255
gene id: 758793:BRPE64_RS22255
uniprot id: R4WP25
names: Similarity
messages: Belongs to the GST superfamily.

758793:BRPE64 RS11770
gene id: 758793:BRPE64_RS11770
uniprot id: R4WYA2
names: Similarity
messages: Belongs to the TrpC family.

758793:BRPE64 RS07890
gene id: 758793:BRPE64_RS07890
uniprot id: R4WH98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

758793:BRPE64 RS23650
gene id: 758793:BRPE64_RS23650
uniprot id: R4WYT4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS01210
gene id: 758793:BRPE64_RS01210
uniprot id: R4WF29
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

758793:BRPE64 RS30130
gene id: 758793:BRPE64_RS30130
uniprot id: R4X4B0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS29860
gene id: 758793:BRPE64_RS29860
uniprot id: R4WTT9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the maleate isomerase family.
messages: Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
messages: Homodimer.
messages: Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate.

758793:BRPE64 RS30205
gene id: 758793:BRPE64_RS30205
uniprot id: R4WU26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS03015
gene id: 758793:BRPE64_RS03015
uniprot id: R4WWW5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS12360
gene id: 758793:BRPE64_RS12360
uniprot id: R4WYH9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

758793:BRPE64 RS05030
gene id: 758793:BRPE64_RS05030
uniprot id: R4WGD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

758793:BRPE64 RS14750
gene id: 758793:BRPE64_RS14750
uniprot id: R4WUY9
names: Similarity
messages: Belongs to the phosphoribulokinase family.

758793:BRPE64 RS08990
gene id: 758793:BRPE64_RS08990
uniprot id: R4WZ41
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS12095
gene id: 758793:BRPE64_RS12095
uniprot id: R4WYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS18195
gene id: 758793:BRPE64_RS18195
uniprot id: R4WLQ5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS18240
gene id: 758793:BRPE64_RS18240
uniprot id: R4X2D0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS12375
gene id: 758793:BRPE64_RS12375
uniprot id: R4WJ20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

758793:BRPE64 RS13540
gene id: 758793:BRPE64_RS13540
uniprot id: R4X0Q2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

758793:BRPE64 RS07480
gene id: 758793:BRPE64_RS07480
uniprot id: S0BC46
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS15920
gene id: 758793:BRPE64_RS15920
uniprot id: R4X1J5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

758793:BRPE64 RS21725
gene id: 758793:BRPE64_RS21725
uniprot id: R4X3E7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

758793:BRPE64 RS31520
gene id: 758793:BRPE64_RS31520
uniprot id: A0A060PH77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS05855
gene id: 758793:BRPE64_RS05855
uniprot id: R4WPZ8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

758793:BRPE64 RS31775
gene id: 758793:BRPE64_RS31775
uniprot id: A0A060PJV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS12280
gene id: 758793:BRPE64_RS12280
uniprot id: R4WJ09
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS07930
gene id: 758793:BRPE64_RS07930
uniprot id: R4WR58
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758793:BRPE64 RS20005
gene id: 758793:BRPE64_RS20005
uniprot id: R4X143
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

758793:BRPE64 RS30350
gene id: 758793:BRPE64_RS30350
uniprot id: R4X5E4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

758793:BRPE64 RS24925
gene id: 758793:BRPE64_RS24925
uniprot id: R4X449
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

758793:BRPE64 RS28710
gene id: 758793:BRPE64_RS28710
uniprot id: R4X0R2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

758793:BRPE64 RS27165
gene id: 758793:BRPE64_RS27165
uniprot id: R4X031
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS16135
gene id: 758793:BRPE64_RS16135
uniprot id: R4WKM2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

758793:BRPE64 RS29465
gene id: 758793:BRPE64_RS29465
uniprot id: R4X0Z1
names: Similarity
messages: Belongs to the DapA family.

758793:BRPE64 RS27390
gene id: 758793:BRPE64_RS27390
uniprot id: R4WS74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS12495
gene id: 758793:BRPE64_RS12495
uniprot id: R4WJ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

758793:BRPE64 RS15640
gene id: 758793:BRPE64_RS15640
uniprot id: R4X1G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS19340
gene id: 758793:BRPE64_RS19340
uniprot id: R4WXB9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS32140
gene id: 758793:BRPE64_RS32140
uniprot id: R4WQ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

758793:BRPE64 RS05945
gene id: 758793:BRPE64_RS05945
uniprot id: R4WGN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

758793:BRPE64 RS04870
gene id: 758793:BRPE64_RS04870
uniprot id: R4WV31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS28830
gene id: 758793:BRPE64_RS28830
uniprot id: R4X0S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS04005
gene id: 758793:BRPE64_RS04005
uniprot id: R4WFR9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS03045
gene id: 758793:BRPE64_RS03045
uniprot id: R4WFQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS06035
gene id: 758793:BRPE64_RS06035
uniprot id: R4WQ30
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

758793:BRPE64 RS30125
gene id: 758793:BRPE64_RS30125
uniprot id: R4X176
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS10615
gene id: 758793:BRPE64_RS10615
uniprot id: R4WSM7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

758793:BRPE64 RS00095
gene id: 758793:BRPE64_RS00095
uniprot id: R4WER7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS25805
gene id: 758793:BRPE64_RS25805
uniprot id: R4WR79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS05235
gene id: 758793:BRPE64_RS05235
uniprot id: R4WV94
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

758793:BRPE64 RS08850
gene id: 758793:BRPE64_RS08850
uniprot id: R4WX78
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

758793:BRPE64 RS30180
gene id: 758793:BRPE64_RS30180
uniprot id: R4X5D0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

758793:BRPE64 RS13585
gene id: 758793:BRPE64_RS13585
uniprot id: R4X0R1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

758793:BRPE64 RS05795
gene id: 758793:BRPE64_RS05795
uniprot id: R4WXX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

758793:BRPE64 RS05590
gene id: 758793:BRPE64_RS05590
uniprot id: R4WGJ2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

758793:BRPE64 RS13170
gene id: 758793:BRPE64_RS13170
uniprot id: R4X0K8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

758793:BRPE64 RS04685
gene id: 758793:BRPE64_RS04685
uniprot id: R4WG04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

758793:BRPE64 RS26960
gene id: 758793:BRPE64_RS26960
uniprot id: R4X3H5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS29380
gene id: 758793:BRPE64_RS29380
uniprot id: R4WTI5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

758793:BRPE64 RS02225
gene id: 758793:BRPE64_RS02225
uniprot id: R4WF76
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS00665
gene id: 758793:BRPE64_RS00665
uniprot id: R4WSN4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS26680
gene id: 758793:BRPE64_RS26680
uniprot id: R4X3E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

758793:BRPE64 RS02255
gene id: 758793:BRPE64_RS02255
uniprot id: R4WFH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

758793:BRPE64 RS17680
gene id: 758793:BRPE64_RS17680
uniprot id: R4X0D0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

758793:BRPE64 RS04225
gene id: 758793:BRPE64_RS04225
uniprot id: R4WG21
names: Similarity
messages: Belongs to the rubredoxin family.

758793:BRPE64 RS31085
gene id: 758793:BRPE64_RS31085
uniprot id: A0A060PQV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS26500
gene id: 758793:BRPE64_RS26500
uniprot id: R4WRQ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

758793:BRPE64 RS16745
gene id: 758793:BRPE64_RS16745
uniprot id: R4X040
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
messages: Homooctamer; tetramer of dimers.
messages: Reaction proceeds via a syn dehydration.

758793:BRPE64 RS19735
gene id: 758793:BRPE64_RS19735
uniprot id: R4X2X4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS04470
gene id: 758793:BRPE64_RS04470
uniprot id: R4WUS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

758793:BRPE64 RS01485
gene id: 758793:BRPE64_RS01485
uniprot id: R4WF61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

758793:BRPE64 RS11500
gene id: 758793:BRPE64_RS11500
uniprot id: R4WT45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

758793:BRPE64 RS29680
gene id: 758793:BRPE64_RS29680
uniprot id: R4WTT1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS13615
gene id: 758793:BRPE64_RS13615
uniprot id: R4WJD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

758793:BRPE64 RS07310
gene id: 758793:BRPE64_RS07310
uniprot id: R4WQU5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

758793:BRPE64 RS12910
gene id: 758793:BRPE64_RS12910
uniprot id: R4X0H9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS23740
gene id: 758793:BRPE64_RS23740
uniprot id: R4WQ17
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS00590
gene id: 758793:BRPE64_RS00590
uniprot id: R4WSM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

758793:BRPE64 RS30040
gene id: 758793:BRPE64_RS30040
uniprot id: R4WU22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

758793:BRPE64 RS14155
gene id: 758793:BRPE64_RS14155
uniprot id: R4WJM8
names: Similarity
messages: Belongs to the IlvD/Edd family.

758793:BRPE64 RS25895
gene id: 758793:BRPE64_RS25895
uniprot id: R4X381
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS21845
gene id: 758793:BRPE64_RS21845
uniprot id: R4X3F6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19945
gene id: 758793:BRPE64_RS19945
uniprot id: R4X2Z8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS31150
gene id: 758793:BRPE64_RS31150
uniprot id: A0A060PQW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

758793:BRPE64 RS07980
gene id: 758793:BRPE64_RS07980
uniprot id: R4WR68
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

758793:BRPE64 RS17610
gene id: 758793:BRPE64_RS17610
uniprot id: R4X261
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aromatic amine dehydrogenase light chain family.
messages: Heterotetramer of two light and two heavy chains.
messages: Periplasm

758793:BRPE64 RS15765
gene id: 758793:BRPE64_RS15765
uniprot id: R4WKE7
names: Similarity
messages: Belongs to the PrpD family.

758793:BRPE64 RS08755
gene id: 758793:BRPE64_RS08755
uniprot id: R4WHE9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS17410
gene id: 758793:BRPE64_RS17410
uniprot id: R4WLC6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS01475
gene id: 758793:BRPE64_RS01475
uniprot id: R4WVX5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758793:BRPE64 RS23355
gene id: 758793:BRPE64_RS23355
uniprot id: R4WPQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS04170
gene id: 758793:BRPE64_RS04170
uniprot id: R4WFT6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS17065
gene id: 758793:BRPE64_RS17065
uniprot id: R4X201
names: Similarity
messages: Belongs to the thioesterase PaaI family.

758793:BRPE64 RS07545
gene id: 758793:BRPE64_RS07545
uniprot id: R4WYM1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

758793:BRPE64 RS02590
gene id: 758793:BRPE64_RS02590
uniprot id: R4WTU5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS09655
gene id: 758793:BRPE64_RS09655
uniprot id: R4WS55
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

758793:BRPE64 RS24315
gene id: 758793:BRPE64_RS24315
uniprot id: R4X3Z4
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

758793:BRPE64 RS29470
gene id: 758793:BRPE64_RS29470
uniprot id: R4X456
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05045
gene id: 758793:BRPE64_RS05045
uniprot id: R4WXN5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

758793:BRPE64 RS05345
gene id: 758793:BRPE64_RS05345
uniprot id: R4WG88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

758793:BRPE64 RS06585
gene id: 758793:BRPE64_RS06585
uniprot id: R4WGU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS26255
gene id: 758793:BRPE64_RS26255
uniprot id: R4X3B5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS18330
gene id: 758793:BRPE64_RS18330
uniprot id: R4X0K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates precorrin-2 at the C-20 position to produce precorrin-3A.

758793:BRPE64 RS05585
gene id: 758793:BRPE64_RS05585
uniprot id: R4WGB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS30175
gene id: 758793:BRPE64_RS30175
uniprot id: R4X4B4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

758793:BRPE64 RS31610
gene id: 758793:BRPE64_RS31610
uniprot id: A0A060PKR6
names: Similarity
messages: Belongs to the DapA family.

758793:BRPE64 RS24290
gene id: 758793:BRPE64_RS24290
uniprot id: R4X3Z2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS13050
gene id: 758793:BRPE64_RS13050
uniprot id: R4WJ43
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

758793:BRPE64 RS12255
gene id: 758793:BRPE64_RS12255
uniprot id: R4WIU0
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

758793:BRPE64 RS11745
gene id: 758793:BRPE64_RS11745
uniprot id: R4WT97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

758793:BRPE64 RS17510
gene id: 758793:BRPE64_RS17510
uniprot id: R4WLD9
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

758793:BRPE64 RS10410
gene id: 758793:BRPE64_RS10410
uniprot id: R4WI45
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS00075
gene id: 758793:BRPE64_RS00075
uniprot id: R4WSC6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS24050
gene id: 758793:BRPE64_RS24050
uniprot id: R4X2M5
names: Similarity
messages: Belongs to the GST superfamily. Omega family.

758793:BRPE64 RS00275
gene id: 758793:BRPE64_RS00275
uniprot id: R4WEL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

758793:BRPE64 RS23995
gene id: 758793:BRPE64_RS23995
uniprot id: R4WYY5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS07690
gene id: 758793:BRPE64_RS07690
uniprot id: R4WWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

758793:BRPE64 RS02990
gene id: 758793:BRPE64_RS02990
uniprot id: R4WWW3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

758793:BRPE64 RS23645
gene id: 758793:BRPE64_RS23645
uniprot id: R4WQ64
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

758793:BRPE64 RS02755
gene id: 758793:BRPE64_RS02755
uniprot id: R4WWR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

758793:BRPE64 RS22080
gene id: 758793:BRPE64_RS22080
uniprot id: R4WY94
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS13405
gene id: 758793:BRPE64_RS13405
uniprot id: R4WU59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

758793:BRPE64 RS12650
gene id: 758793:BRPE64_RS12650
uniprot id: R4WIY3
names: Similarity
messages: Belongs to the malic enzymes family.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

758793:BRPE64 RS22290
gene id: 758793:BRPE64_RS22290
uniprot id: R4X3J1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS13150
gene id: 758793:BRPE64_RS13150
uniprot id: R4WJ55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

758793:BRPE64 RS09990
gene id: 758793:BRPE64_RS09990
uniprot id: R4WSA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS16880
gene id: 758793:BRPE64_RS16880
uniprot id: R4WL49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

758793:BRPE64 RS25180
gene id: 758793:BRPE64_RS25180
uniprot id: R4X311
names: Similarity
messages: Belongs to the DapA family.

758793:BRPE64 RS09845
gene id: 758793:BRPE64_RS09845
uniprot id: R4WS82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

758793:BRPE64 RS20225
gene id: 758793:BRPE64_RS20225
uniprot id: R4X171
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

758793:BRPE64 RS20245
gene id: 758793:BRPE64_RS20245
uniprot id: R4WXK3
names: Similarity
messages: Belongs to the hyi family.

758793:BRPE64 RS08885
gene id: 758793:BRPE64_RS08885
uniprot id: R4WHG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

758793:BRPE64 RS09275
gene id: 758793:BRPE64_RS09275
uniprot id: R4WXD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS10915
gene id: 758793:BRPE64_RS10915
uniprot id: R4WIC4
names: Similarity
messages: Belongs to the CFA/CMAS family.

758793:BRPE64 RS18755
gene id: 758793:BRPE64_RS18755
uniprot id: R4X2I1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

758793:BRPE64 RS01235
gene id: 758793:BRPE64_RS01235
uniprot id: R4WMB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

758793:BRPE64 RS05980
gene id: 758793:BRPE64_RS05980
uniprot id: R4WXZ9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS27225
gene id: 758793:BRPE64_RS27225
uniprot id: R4X4P5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS13645
gene id: 758793:BRPE64_RS13645
uniprot id: R4WYY0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

758793:BRPE64 RS00935
gene id: 758793:BRPE64_RS00935
uniprot id: R4WM73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

758793:BRPE64 RS15470
gene id: 758793:BRPE64_RS15470
uniprot id: R4WKH9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS18640
gene id: 758793:BRPE64_RS18640
uniprot id: R4X2H0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS21560
gene id: 758793:BRPE64_RS21560
uniprot id: R4X3D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS08200
gene id: 758793:BRPE64_RS08200
uniprot id: R4WYU3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS09330
gene id: 758793:BRPE64_RS09330
uniprot id: R4WZ85
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

758793:BRPE64 RS18430
gene id: 758793:BRPE64_RS18430
uniprot id: R4WM49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS30890
gene id: 758793:BRPE64_RS30890
uniprot id: A0A060PKA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS26195
gene id: 758793:BRPE64_RS26195
uniprot id: R4WRU0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

758793:BRPE64 RS02725
gene id: 758793:BRPE64_RS02725
uniprot id: R4WTX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

758793:BRPE64 RS16160
gene id: 758793:BRPE64_RS16160
uniprot id: R4X1M0
names: Similarity
messages: Belongs to the ketopantoate reductase family.

758793:BRPE64 RS23710
gene id: 758793:BRPE64_RS23710
uniprot id: R4X3V5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

758793:BRPE64 RS05645
gene id: 758793:BRPE64_RS05645
uniprot id: R4WVG9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

758793:BRPE64 RS07610
gene id: 758793:BRPE64_RS07610
uniprot id: R4WQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

758793:BRPE64 RS28215
gene id: 758793:BRPE64_RS28215
uniprot id: R4X4X5
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

758793:BRPE64 RS06295
gene id: 758793:BRPE64_RS06295
uniprot id: R4WVT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

758793:BRPE64 RS10010
gene id: 758793:BRPE64_RS10010
uniprot id: R4WSB1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

758793:BRPE64 RS30925
gene id: 758793:BRPE64_RS30925
uniprot id: A0A060PRA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS08950
gene id: 758793:BRPE64_RS08950
uniprot id: R4WZ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

758793:BRPE64 RS05725
gene id: 758793:BRPE64_RS05725
uniprot id: R4WGC9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

758793:BRPE64 RS19835
gene id: 758793:BRPE64_RS19835
uniprot id: R4WXG6
names: Similarity
messages: Belongs to the ModE family.

758793:BRPE64 RS07580
gene id: 758793:BRPE64_RS07580
uniprot id: R4WH62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

758793:BRPE64 RS27310
gene id: 758793:BRPE64_RS27310
uniprot id: R4X4Q3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS23520
gene id: 758793:BRPE64_RS23520
uniprot id: R4X3T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS08460
gene id: 758793:BRPE64_RS08460
uniprot id: R4WYW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

758793:BRPE64 RS08685
gene id: 758793:BRPE64_RS08685
uniprot id: R4WHI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

758793:BRPE64 RS08025
gene id: 758793:BRPE64_RS08025
uniprot id: R4WWV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

758793:BRPE64 RS29305
gene id: 758793:BRPE64_RS29305
uniprot id: R4WTH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS12085
gene id: 758793:BRPE64_RS12085
uniprot id: R4WIS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS24910
gene id: 758793:BRPE64_RS24910
uniprot id: R4WQV3
names: Similarity
messages: Belongs to the CFA/CMAS family.

758793:BRPE64 RS19820
gene id: 758793:BRPE64_RS19820
uniprot id: R4WXG3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

758793:BRPE64 RS02785
gene id: 758793:BRPE64_RS02785
uniprot id: R4WFE8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS25145
gene id: 758793:BRPE64_RS25145
uniprot id: R4WQQ5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

758793:BRPE64 RS06310
gene id: 758793:BRPE64_RS06310
uniprot id: R4WGR9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

758793:BRPE64 RS01760
gene id: 758793:BRPE64_RS01760
uniprot id: R4WF17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

758793:BRPE64 RS14420
gene id: 758793:BRPE64_RS14420
uniprot id: R4X150
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

758793:BRPE64 RS29315
gene id: 758793:BRPE64_RS29315
uniprot id: R4X0X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

758793:BRPE64 RS22720
gene id: 758793:BRPE64_RS22720
uniprot id: R4WYF2
names: Similarity
messages: Belongs to the YciI family.

758793:BRPE64 RS29625
gene id: 758793:BRPE64_RS29625
uniprot id: R4X583
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS13155
gene id: 758793:BRPE64_RS13155
uniprot id: R4WJC3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

758793:BRPE64 RS00605
gene id: 758793:BRPE64_RS00605
uniprot id: R4WEX1
names: Similarity
messages: Belongs to the MotB family.

758793:BRPE64 RS20600
gene id: 758793:BRPE64_RS20600
uniprot id: R4WXQ4
names: Similarity
messages: Belongs to the GcvT family.

758793:BRPE64 RS29455
gene id: 758793:BRPE64_RS29455
uniprot id: R4WTJ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS06060
gene id: 758793:BRPE64_RS06060
uniprot id: R4WGP3
names: Similarity
messages: Belongs to the UPF0303 family.

758793:BRPE64 RS30945
gene id: 758793:BRPE64_RS30945
uniprot id: A0A060PQR6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS16825
gene id: 758793:BRPE64_RS16825
uniprot id: R4X1X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS09605
gene id: 758793:BRPE64_RS09605
uniprot id: R4WS50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

758793:BRPE64 RS19040
gene id: 758793:BRPE64_RS19040
uniprot id: R4WX74
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

758793:BRPE64 RS09440
gene id: 758793:BRPE64_RS09440
uniprot id: R4WS02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

758793:BRPE64 RS08625
gene id: 758793:BRPE64_RS08625
uniprot id: R4WRH6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

758793:BRPE64 RS16385
gene id: 758793:BRPE64_RS16385
uniprot id: R4X1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

758793:BRPE64 RS02780
gene id: 758793:BRPE64_RS02780
uniprot id: R4WWS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

758793:BRPE64 RS08940
gene id: 758793:BRPE64_RS08940
uniprot id: R4WRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS00915
gene id: 758793:BRPE64_RS00915
uniprot id: R4WST2
names: Subcellular Location Annotation
messages: Cytoplasm

758793:BRPE64 RS24085
gene id: 758793:BRPE64_RS24085
uniprot id: R4WQH0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS09975
gene id: 758793:BRPE64_RS09975
uniprot id: R4WZG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758793:BRPE64 RS11155
gene id: 758793:BRPE64_RS11155
uniprot id: R4WIG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

758793:BRPE64 RS19705
gene id: 758793:BRPE64_RS19705
uniprot id: R4WXF2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

758793:BRPE64 RS06705
gene id: 758793:BRPE64_RS06705
uniprot id: R4WGV8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

758793:BRPE64 RS11540
gene id: 758793:BRPE64_RS11540
uniprot id: R4X009
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

758793:BRPE64 RS22795
gene id: 758793:BRPE64_RS22795
uniprot id: R4X254
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

758793:BRPE64 RS12820
gene id: 758793:BRPE64_RS12820
uniprot id: R4WJ72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS12140
gene id: 758793:BRPE64_RS12140
uniprot id: R4WTJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

758793:BRPE64 RS27715
gene id: 758793:BRPE64_RS27715
uniprot id: R4WSF6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS13365
gene id: 758793:BRPE64_RS13365
uniprot id: R4X0M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

758793:BRPE64 RS00190
gene id: 758793:BRPE64_RS00190
uniprot id: R4WSE8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

758793:BRPE64 RS23035
gene id: 758793:BRPE64_RS23035
uniprot id: R4X3P6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19120
gene id: 758793:BRPE64_RS19120
uniprot id: R4WMD1
names: Similarity
messages: Belongs to the universal stress protein A family.

758793:BRPE64 RS05830
gene id: 758793:BRPE64_RS05830
uniprot id: R4WPZ4
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

758793:BRPE64 RS03875
gene id: 758793:BRPE64_RS03875
uniprot id: R4WFY6
names: Similarity
messages: Belongs to the YggT family.

758793:BRPE64 RS29730
gene id: 758793:BRPE64_RS29730
uniprot id: R4WTU3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

758793:BRPE64 RS18955
gene id: 758793:BRPE64_RS18955
uniprot id: R4WM65
names: Similarity
messages: Belongs to the GSP E family.

758793:BRPE64 RS26850
gene id: 758793:BRPE64_RS26850
uniprot id: R4X4L1
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

758793:BRPE64 RS12425
gene id: 758793:BRPE64_RS12425
uniprot id: R4WJ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

758793:BRPE64 RS00640
gene id: 758793:BRPE64_RS00640
uniprot id: R4WSN0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

758793:BRPE64 RS06810
gene id: 758793:BRPE64_RS06810
uniprot id: R4WGW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

758793:BRPE64 RS09915
gene id: 758793:BRPE64_RS09915
uniprot id: R4WHY4
names: Similarity
messages: Belongs to the histone deacetylase family.

758793:BRPE64 RS13445
gene id: 758793:BRPE64_RS13445
uniprot id: R4WU70
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS08180
gene id: 758793:BRPE64_RS08180
uniprot id: R4WH81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

758793:BRPE64 RS23805
gene id: 758793:BRPE64_RS23805
uniprot id: R4X3V9
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

758793:BRPE64 RS26685
gene id: 758793:BRPE64_RS26685
uniprot id: R4X4J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

758793:BRPE64 RS10590
gene id: 758793:BRPE64_RS10590
uniprot id: R4WSM4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

758793:BRPE64 RS27355
gene id: 758793:BRPE64_RS27355
uniprot id: R4X3L3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS12970
gene id: 758793:BRPE64_RS12970
uniprot id: R4WYP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS10820
gene id: 758793:BRPE64_RS10820
uniprot id: R4WSS0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

758793:BRPE64 RS09125
gene id: 758793:BRPE64_RS09125
uniprot id: R4WXB5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

758793:BRPE64 RS16855
gene id: 758793:BRPE64_RS16855
uniprot id: R4WL47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

758793:BRPE64 RS02145
gene id: 758793:BRPE64_RS02145
uniprot id: R4WTH2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

758793:BRPE64 RS06725
gene id: 758793:BRPE64_RS06725
uniprot id: R4WGQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

758793:BRPE64 RS03735
gene id: 758793:BRPE64_RS03735
uniprot id: R4WX56
names: Function
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate.

758793:BRPE64 RS00090
gene id: 758793:BRPE64_RS00090
uniprot id: R4WEK4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

758793:BRPE64 RS05660
gene id: 758793:BRPE64_RS05660
uniprot id: R4WGK1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

758793:BRPE64 RS27210
gene id: 758793:BRPE64_RS27210
uniprot id: R4WSA5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS25555
gene id: 758793:BRPE64_RS25555
uniprot id: R4WRC2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS00490
gene id: 758793:BRPE64_RS00490
uniprot id: R4WEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

758793:BRPE64 RS13065
gene id: 758793:BRPE64_RS13065
uniprot id: R4WYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

758793:BRPE64 RS15925
gene id: 758793:BRPE64_RS15925
uniprot id: R4WKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS02650
gene id: 758793:BRPE64_RS02650
uniprot id: R4WFD5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS15740
gene id: 758793:BRPE64_RS15740
uniprot id: R4WKE2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS20575
gene id: 758793:BRPE64_RS20575
uniprot id: R4WXQ0
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

758793:BRPE64 RS20700
gene id: 758793:BRPE64_RS20700
uniprot id: R4X1D6
names: Similarity
messages: Belongs to the UxaA family.

758793:BRPE64 RS04250
gene id: 758793:BRPE64_RS04250
uniprot id: R4WG22
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS01160
gene id: 758793:BRPE64_RS01160
uniprot id: R4WSX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

758793:BRPE64 RS03920
gene id: 758793:BRPE64_RS03920
uniprot id: R4WNT5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

758793:BRPE64 RS06395
gene id: 758793:BRPE64_RS06395
uniprot id: R4WGL1
names: Similarity
messages: Belongs to the threonine synthase family.

758793:BRPE64 RS23890
gene id: 758793:BRPE64_RS23890
uniprot id: R4WYX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS02075
gene id: 758793:BRPE64_RS02075
uniprot id: R4WW93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

758793:BRPE64 RS29545
gene id: 758793:BRPE64_RS29545
uniprot id: R4X462
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS23790
gene id: 758793:BRPE64_RS23790
uniprot id: R4WQC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS01285
gene id: 758793:BRPE64_RS01285
uniprot id: R4WMC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

758793:BRPE64 RS05715
gene id: 758793:BRPE64_RS05715
uniprot id: R4WVH9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

758793:BRPE64 RS02290
gene id: 758793:BRPE64_RS02290
uniprot id: R4WTP3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

758793:BRPE64 RS20645
gene id: 758793:BRPE64_RS20645
uniprot id: R4WNE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS25665
gene id: 758793:BRPE64_RS25665
uniprot id: R4X4B3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS02340
gene id: 758793:BRPE64_RS02340
uniprot id: R4WFA4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

758793:BRPE64 RS16010
gene id: 758793:BRPE64_RS16010
uniprot id: R4WZR7
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

758793:BRPE64 RS11285
gene id: 758793:BRPE64_RS11285
uniprot id: R4WY32
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

758793:BRPE64 RS06805
gene id: 758793:BRPE64_RS06805
uniprot id: R4WGR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

758793:BRPE64 RS11170
gene id: 758793:BRPE64_RS11170
uniprot id: R4WZV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

758793:BRPE64 RS00220
gene id: 758793:BRPE64_RS00220
uniprot id: R4WV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

758793:BRPE64 RS22740
gene id: 758793:BRPE64_RS22740
uniprot id: R4WYF5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

758793:BRPE64 RS30020
gene id: 758793:BRPE64_RS30020
uniprot id: R4X160
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS21285
gene id: 758793:BRPE64_RS21285
uniprot id: R4WY02
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS28675
gene id: 758793:BRPE64_RS28675
uniprot id: R4WT59
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

758793:BRPE64 RS07300
gene id: 758793:BRPE64_RS07300
uniprot id: R4WH01
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS22800
gene id: 758793:BRPE64_RS22800
uniprot id: R4X3N0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS13130
gene id: 758793:BRPE64_RS13130
uniprot id: R4WJB9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

758793:BRPE64 RS29670
gene id: 758793:BRPE64_RS29670
uniprot id: R4X587
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS02095
gene id: 758793:BRPE64_RS02095
uniprot id: R4WTG4
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS04010
gene id: 758793:BRPE64_RS04010
uniprot id: R4WG02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

758793:BRPE64 RS10235
gene id: 758793:BRPE64_RS10235
uniprot id: R4WI24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

758793:BRPE64 RS09255
gene id: 758793:BRPE64_RS09255
uniprot id: R4WZ78
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

758793:BRPE64 RS02355
gene id: 758793:BRPE64_RS02355
uniprot id: R4WTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

758793:BRPE64 RS02655
gene id: 758793:BRPE64_RS02655
uniprot id: R4WFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS15795
gene id: 758793:BRPE64_RS15795
uniprot id: R4WKP6
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

758793:BRPE64 RS25885
gene id: 758793:BRPE64_RS25885
uniprot id: R4WRK1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS17280
gene id: 758793:BRPE64_RS17280
uniprot id: R4WLJ6
names: Similarity
messages: Belongs to the RutC family.

758793:BRPE64 RS07015
gene id: 758793:BRPE64_RS07015
uniprot id: R4WW79
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS03020
gene id: 758793:BRPE64_RS03020
uniprot id: R4WFH0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS09820
gene id: 758793:BRPE64_RS09820
uniprot id: R4WS80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

758793:BRPE64 RS19275
gene id: 758793:BRPE64_RS19275
uniprot id: R4X0X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

758793:BRPE64 RS13410
gene id: 758793:BRPE64_RS13410
uniprot id: R4WYU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

758793:BRPE64 RS12720
gene id: 758793:BRPE64_RS12720
uniprot id: R4WJ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

758793:BRPE64 RS04790
gene id: 758793:BRPE64_RS04790
uniprot id: R4WV18
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

758793:BRPE64 RS02840
gene id: 758793:BRPE64_RS02840
uniprot id: R4WNA9
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS19720
gene id: 758793:BRPE64_RS19720
uniprot id: R4WMX6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

758793:BRPE64 RS16580
gene id: 758793:BRPE64_RS16580
uniprot id: R4WL58
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS14275
gene id: 758793:BRPE64_RS14275
uniprot id: R4WJP7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS05080
gene id: 758793:BRPE64_RS05080
uniprot id: R4WGD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

758793:BRPE64 RS26875
gene id: 758793:BRPE64_RS26875
uniprot id: R4X4L3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS02055
gene id: 758793:BRPE64_RS02055
uniprot id: R4WF52
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

758793:BRPE64 RS28480
gene id: 758793:BRPE64_RS28480
uniprot id: R4X3X1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758793:BRPE64 RS12115
gene id: 758793:BRPE64_RS12115
uniprot id: R4WTJ1
names: Similarity
messages: Belongs to the MlaA family.

758793:BRPE64 RS13425
gene id: 758793:BRPE64_RS13425
uniprot id: R4WJG5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS24890
gene id: 758793:BRPE64_RS24890
uniprot id: R4WZ79
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

758793:BRPE64 RS01540
gene id: 758793:BRPE64_RS01540
uniprot id: R4WVY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS22560
gene id: 758793:BRPE64_RS22560
uniprot id: R4WPG0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

758793:BRPE64 RS07630
gene id: 758793:BRPE64_RS07630
uniprot id: R4WH67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

758793:BRPE64 RS02730
gene id: 758793:BRPE64_RS02730
uniprot id: R4WWR5
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

758793:BRPE64 RS11165
gene id: 758793:BRPE64_RS11165
uniprot id: R4WY21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

758793:BRPE64 RS08840
gene id: 758793:BRPE64_RS08840
uniprot id: R4WHK1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS19190
gene id: 758793:BRPE64_RS19190
uniprot id: R4WME2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS31025
gene id: 758793:BRPE64_RS31025
uniprot id: A0A060PGW9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

758793:BRPE64 RS23695
gene id: 758793:BRPE64_RS23695
uniprot id: R4WQ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS12460
gene id: 758793:BRPE64_RS12460
uniprot id: R4WTP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

758793:BRPE64 RS22115
gene id: 758793:BRPE64_RS22115
uniprot id: R4X3H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS12060
gene id: 758793:BRPE64_RS12060
uniprot id: R4WIR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS01425
gene id: 758793:BRPE64_RS01425
uniprot id: R4WVW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS06305
gene id: 758793:BRPE64_RS06305
uniprot id: R4WGJ9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

758793:BRPE64 RS16630
gene id: 758793:BRPE64_RS16630
uniprot id: R4X010
names: Similarity
messages: Belongs to the MotB family.

758793:BRPE64 RS10140
gene id: 758793:BRPE64_RS10140
uniprot id: R4WSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

758793:BRPE64 RS12265
gene id: 758793:BRPE64_RS12265
uniprot id: R4WTK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

758793:BRPE64 RS18915
gene id: 758793:BRPE64_RS18915
uniprot id: R4WX54
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS03095
gene id: 758793:BRPE64_RS03095
uniprot id: R4WFR4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

758793:BRPE64 RS11315
gene id: 758793:BRPE64_RS11315
uniprot id: R4WZX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

758793:BRPE64 RS22540
gene id: 758793:BRPE64_RS22540
uniprot id: R4WYD5
names: Similarity
messages: Belongs to the UxaA family.

758793:BRPE64 RS00320
gene id: 758793:BRPE64_RS00320
uniprot id: R4WV98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

758793:BRPE64 RS05220
gene id: 758793:BRPE64_RS05220
uniprot id: R4WG78
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

758793:BRPE64 RS09850
gene id: 758793:BRPE64_RS09850
uniprot id: R4WXL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

758793:BRPE64 RS18665
gene id: 758793:BRPE64_RS18665
uniprot id: R4X2H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS22265
gene id: 758793:BRPE64_RS22265
uniprot id: R4X1Y5
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

758793:BRPE64 RS16100
gene id: 758793:BRPE64_RS16100
uniprot id: R4WKW2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS11765
gene id: 758793:BRPE64_RS11765
uniprot id: R4WTA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS13390
gene id: 758793:BRPE64_RS13390
uniprot id: R4X0N0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS06365
gene id: 758793:BRPE64_RS06365
uniprot id: R4WVV0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

758793:BRPE64 RS25715
gene id: 758793:BRPE64_RS25715
uniprot id: R4WR53
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS09840
gene id: 758793:BRPE64_RS09840
uniprot id: R4WHX7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

758793:BRPE64 RS17840
gene id: 758793:BRPE64_RS17840
uniprot id: R4WWI4
names: Subcellular Location Annotation
messages: Periplasm

758793:BRPE64 RS00680
gene id: 758793:BRPE64_RS00680
uniprot id: R4WEX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

758793:BRPE64 RS03690
gene id: 758793:BRPE64_RS03690
uniprot id: R4WFW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

758793:BRPE64 RS19805
gene id: 758793:BRPE64_RS19805
uniprot id: R4X2Y2
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

758793:BRPE64 RS07280
gene id: 758793:BRPE64_RS07280
uniprot id: R4WH31
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

758793:BRPE64 RS22370
gene id: 758793:BRPE64_RS22370
uniprot id: R4WYC2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS01050
gene id: 758793:BRPE64_RS01050
uniprot id: R4WES8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

758793:BRPE64 RS23490
gene id: 758793:BRPE64_RS23490
uniprot id: R4WYR0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

758793:BRPE64 RS11640
gene id: 758793:BRPE64_RS11640
uniprot id: R4X020
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

758793:BRPE64 RS00880
gene id: 758793:BRPE64_RS00880
uniprot id: R4WF01
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

758793:BRPE64 RS10925
gene id: 758793:BRPE64_RS10925
uniprot id: R4WXZ4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

758793:BRPE64 RS17845
gene id: 758793:BRPE64_RS17845
uniprot id: R4X0E8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

758793:BRPE64 RS05385
gene id: 758793:BRPE64_RS05385
uniprot id: R4WVC0
names: Similarity
messages: Belongs to the RutC family.

758793:BRPE64 RS29140
gene id: 758793:BRPE64_RS29140
uniprot id: R4X539
names: Similarity
messages: Belongs to the PrpD family.

758793:BRPE64 RS30300
gene id: 758793:BRPE64_RS30300
uniprot id: R4X5E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

758793:BRPE64 RS00155
gene id: 758793:BRPE64_RS00155
uniprot id: R4WLU3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

758793:BRPE64 RS06795
gene id: 758793:BRPE64_RS06795
uniprot id: R4WW31
names: Similarity
messages: Belongs to the UPF0229 family.

758793:BRPE64 RS09470
gene id: 758793:BRPE64_RS09470
uniprot id: R4WXG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

758793:BRPE64 RS03005
gene id: 758793:BRPE64_RS03005
uniprot id: R4WND7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

758793:BRPE64 RS09265
gene id: 758793:BRPE64_RS09265
uniprot id: R4WHP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

758793:BRPE64 RS08385
gene id: 758793:BRPE64_RS08385
uniprot id: R4WX12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

758793:BRPE64 RS15510
gene id: 758793:BRPE64_RS15510
uniprot id: R4X1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

758793:BRPE64 RS11145
gene id: 758793:BRPE64_RS11145
uniprot id: R4WZV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

758793:BRPE64 RS28860
gene id: 758793:BRPE64_RS28860
uniprot id: R4X524
names: Similarity
messages: Belongs to the peptidase S33 family.

758793:BRPE64 RS31260
gene id: 758793:BRPE64_RS31260
uniprot id: A0A060PJG4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS25455
gene id: 758793:BRPE64_RS25455
uniprot id: R4X496
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

758793:BRPE64 RS14460
gene id: 758793:BRPE64_RS14460
uniprot id: R4WUV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

758793:BRPE64 RS01520
gene id: 758793:BRPE64_RS01520
uniprot id: R4WVY2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS30210
gene id: 758793:BRPE64_RS30210
uniprot id: R4WU62
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

758793:BRPE64 RS15020
gene id: 758793:BRPE64_RS15020
uniprot id: R4X1A4
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

758793:BRPE64 RS16310
gene id: 758793:BRPE64_RS16310
uniprot id: R4WZW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

758793:BRPE64 RS02610
gene id: 758793:BRPE64_RS02610
uniprot id: R4WN67
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS08410
gene id: 758793:BRPE64_RS08410
uniprot id: R4WYW0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

758793:BRPE64 RS19390
gene id: 758793:BRPE64_RS19390
uniprot id: R4WXC3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

758793:BRPE64 RS08650
gene id: 758793:BRPE64_RS08650
uniprot id: R4WYZ4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

758793:BRPE64 RS13845
gene id: 758793:BRPE64_RS13845
uniprot id: R4WJN7
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS21690
gene id: 758793:BRPE64_RS21690
uniprot id: R4WY60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS13100
gene id: 758793:BRPE64_RS13100
uniprot id: R4WJ50
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

758793:BRPE64 RS18250
gene id: 758793:BRPE64_RS18250
uniprot id: R4WWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

758793:BRPE64 RS27120
gene id: 758793:BRPE64_RS27120
uniprot id: R4X3J0
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS17810
gene id: 758793:BRPE64_RS17810
uniprot id: R4WLI5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS02720
gene id: 758793:BRPE64_RS02720
uniprot id: R4WN87
names: Subcellular Location Annotation
messages: Cytoplasm

758793:BRPE64 RS25500
gene id: 758793:BRPE64_RS25500
uniprot id: R4X4A0
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

758793:BRPE64 RS24725
gene id: 758793:BRPE64_RS24725
uniprot id: R4WQR2
names: Similarity
messages: Belongs to the GST superfamily.

758793:BRPE64 RS19310
gene id: 758793:BRPE64_RS19310
uniprot id: R4X2S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

758793:BRPE64 RS17595
gene id: 758793:BRPE64_RS17595
uniprot id: R4WLP1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS12815
gene id: 758793:BRPE64_RS12815
uniprot id: R4WJ10
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS14340
gene id: 758793:BRPE64_RS14340
uniprot id: R4X123
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS03390
gene id: 758793:BRPE64_RS03390
uniprot id: R4WX24
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

758793:BRPE64 RS20360
gene id: 758793:BRPE64_RS20360
uniprot id: R4WMZ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS12635
gene id: 758793:BRPE64_RS12635
uniprot id: R4WTR3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

758793:BRPE64 RS08395
gene id: 758793:BRPE64_RS08395
uniprot id: R4WHF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

758793:BRPE64 RS20125
gene id: 758793:BRPE64_RS20125
uniprot id: R4X317
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

758793:BRPE64 RS01765
gene id: 758793:BRPE64_RS01765
uniprot id: R4WF92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

758793:BRPE64 RS06015
gene id: 758793:BRPE64_RS06015
uniprot id: R4WGN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

758793:BRPE64 RS01675
gene id: 758793:BRPE64_RS01675
uniprot id: R4WF83
names: Similarity
messages: Belongs to the peptidase M24B family.

758793:BRPE64 RS07790
gene id: 758793:BRPE64_RS07790
uniprot id: R4WYQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

758793:BRPE64 RS22965
gene id: 758793:BRPE64_RS22965
uniprot id: R4X276
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

758793:BRPE64 RS07405
gene id: 758793:BRPE64_RS07405
uniprot id: R4WH43
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

758793:BRPE64 RS25480
gene id: 758793:BRPE64_RS25480
uniprot id: R4WQY8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS19250
gene id: 758793:BRPE64_RS19250
uniprot id: R4WXB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS05390
gene id: 758793:BRPE64_RS05390
uniprot id: R4WXS7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

758793:BRPE64 RS02450
gene id: 758793:BRPE64_RS02450
uniprot id: R4WFB6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS20895
gene id: 758793:BRPE64_RS20895
uniprot id: R4X1G4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

758793:BRPE64 RS01855
gene id: 758793:BRPE64_RS01855
uniprot id: R4WMP6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

758793:BRPE64 RS05555
gene id: 758793:BRPE64_RS05555
uniprot id: R4WVF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS19755
gene id: 758793:BRPE64_RS19755
uniprot id: R4X122
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

758793:BRPE64 RS24170
gene id: 758793:BRPE64_RS24170
uniprot id: R4X2N4
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS03040
gene id: 758793:BRPE64_RS03040
uniprot id: R4WFH1
names: PTM
messages: Binds 1 heme c group covalently per subunit.

758793:BRPE64 RS09035
gene id: 758793:BRPE64_RS09035
uniprot id: R4WZ48
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

758793:BRPE64 RS00005
gene id: 758793:BRPE64_RS00005
uniprot id: R4WLS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

758793:BRPE64 RS08945
gene id: 758793:BRPE64_RS08945
uniprot id: R4WX87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS18630
gene id: 758793:BRPE64_RS18630
uniprot id: R4WX07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

758793:BRPE64 RS00430
gene id: 758793:BRPE64_RS00430
uniprot id: R4WVC1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

758793:BRPE64 RS09495
gene id: 758793:BRPE64_RS09495
uniprot id: R4WXG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

758793:BRPE64 RS24025
gene id: 758793:BRPE64_RS24025
uniprot id: R4X2M2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

758793:BRPE64 RS07590
gene id: 758793:BRPE64_RS07590
uniprot id: R4WWL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS01575
gene id: 758793:BRPE64_RS01575
uniprot id: R4WF74
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

758793:BRPE64 RS04195
gene id: 758793:BRPE64_RS04195
uniprot id: R4WFT9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS24450
gene id: 758793:BRPE64_RS24450
uniprot id: R4X2R4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS07440
gene id: 758793:BRPE64_RS07440
uniprot id: R4WWI7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS01175
gene id: 758793:BRPE64_RS01175
uniprot id: R4WVR5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

758793:BRPE64 RS13005
gene id: 758793:BRPE64_RS13005
uniprot id: R4WJ36
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS01880
gene id: 758793:BRPE64_RS01880
uniprot id: R4WMQ1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

758793:BRPE64 RS05350
gene id: 758793:BRPE64_RS05350
uniprot id: R4WGG6
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

758793:BRPE64 RS16375
gene id: 758793:BRPE64_RS16375
uniprot id: R4WVT5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

758793:BRPE64 RS27850
gene id: 758793:BRPE64_RS27850
uniprot id: R4WSJ7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758793:BRPE64 RS05805
gene id: 758793:BRPE64_RS05805
uniprot id: R4WGL5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

758793:BRPE64 RS22420
gene id: 758793:BRPE64_RS22420
uniprot id: R4WYC6
names: Similarity
messages: Belongs to the FGGY kinase family.

758793:BRPE64 RS09545
gene id: 758793:BRPE64_RS09545
uniprot id: R4WZC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

758793:BRPE64 RS11660
gene id: 758793:BRPE64_RS11660
uniprot id: R4WY87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

758793:BRPE64 RS07010
gene id: 758793:BRPE64_RS07010
uniprot id: R4WGY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

758793:BRPE64 RS25855
gene id: 758793:BRPE64_RS25855
uniprot id: R4WRA0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758793:BRPE64 RS01260
gene id: 758793:BRPE64_RS01260
uniprot id: R4WMB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

758793:BRPE64 RS24160
gene id: 758793:BRPE64_RS24160
uniprot id: R4WQI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS17085
gene id: 758793:BRPE64_RS17085
uniprot id: R4X204
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS11235
gene id: 758793:BRPE64_RS11235
uniprot id: R4WY28
names: Similarity
messages: Belongs to the barstar family.

758793:BRPE64 RS18965
gene id: 758793:BRPE64_RS18965
uniprot id: R4WX61
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05490
gene id: 758793:BRPE64_RS05490
uniprot id: R4WXT9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

758793:BRPE64 RS13085
gene id: 758793:BRPE64_RS13085
uniprot id: R4WTZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

758793:BRPE64 RS25930
gene id: 758793:BRPE64_RS25930
uniprot id: R4WRC0
names: Similarity
messages: Belongs to the aldose epimerase family.

758793:BRPE64 RS00010
gene id: 758793:BRPE64_RS00010
uniprot id: R4WSB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

758793:BRPE64 RS05870
gene id: 758793:BRPE64_RS05870
uniprot id: R4WGE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

758793:BRPE64 RS29490
gene id: 758793:BRPE64_RS29490
uniprot id: R4X0Z4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

758793:BRPE64 RS28030
gene id: 758793:BRPE64_RS28030
uniprot id: R4WSU5
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS17795
gene id: 758793:BRPE64_RS17795
uniprot id: R4WWH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

758793:BRPE64 RS07445
gene id: 758793:BRPE64_RS07445
uniprot id: R4WYL0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

758793:BRPE64 RS15350
gene id: 758793:BRPE64_RS15350
uniprot id: R4WV92
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758793:BRPE64 RS09320
gene id: 758793:BRPE64_RS09320
uniprot id: R4WRX8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

758793:BRPE64 RS05820
gene id: 758793:BRPE64_RS05820
uniprot id: R4WGE2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

758793:BRPE64 RS12415
gene id: 758793:BRPE64_RS12415
uniprot id: R4X0C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

758793:BRPE64 RS10045
gene id: 758793:BRPE64_RS10045
uniprot id: R4WHZ9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

758793:BRPE64 RS22495
gene id: 758793:BRPE64_RS22495
uniprot id: R4X215
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS22570
gene id: 758793:BRPE64_RS22570
uniprot id: R4X224
names: Similarity
messages: Belongs to the DapA family.

758793:BRPE64 RS02150
gene id: 758793:BRPE64_RS02150
uniprot id: R4WF66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS30965
gene id: 758793:BRPE64_RS30965
uniprot id: A0A060PQS2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

758793:BRPE64 RS09925
gene id: 758793:BRPE64_RS09925
uniprot id: R4WZG2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

758793:BRPE64 RS03815
gene id: 758793:BRPE64_RS03815
uniprot id: R4WFP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

758793:BRPE64 RS00195
gene id: 758793:BRPE64_RS00195
uniprot id: R4WV76
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

758793:BRPE64 RS25775
gene id: 758793:BRPE64_RS25775
uniprot id: R4X368
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

758793:BRPE64 RS06255
gene id: 758793:BRPE64_RS06255
uniprot id: R4WGJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS14455
gene id: 758793:BRPE64_RS14455
uniprot id: R4WK13
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS28620
gene id: 758793:BRPE64_RS28620
uniprot id: R4X0Q3
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

758793:BRPE64 RS01640
gene id: 758793:BRPE64_RS01640
uniprot id: R4WT58
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

758793:BRPE64 RS23955
gene id: 758793:BRPE64_RS23955
uniprot id: R4X3W6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS30845
gene id: 758793:BRPE64_RS30845
uniprot id: A0A060PR82
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS07685
gene id: 758793:BRPE64_RS07685
uniprot id: R4WR14
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

758793:BRPE64 RS20875
gene id: 758793:BRPE64_RS20875
uniprot id: R4X376
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

758793:BRPE64 RS00585
gene id: 758793:BRPE64_RS00585
uniprot id: R4WM13
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

758793:BRPE64 RS07565
gene id: 758793:BRPE64_RS07565
uniprot id: R4WWK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

758793:BRPE64 RS10155
gene id: 758793:BRPE64_RS10155
uniprot id: R4WI15
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS08505
gene id: 758793:BRPE64_RS08505
uniprot id: R4WX33
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

758793:BRPE64 RS22430
gene id: 758793:BRPE64_RS22430
uniprot id: R4X3K2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS13165
gene id: 758793:BRPE64_RS13165
uniprot id: R4WYS1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

758793:BRPE64 RS22095
gene id: 758793:BRPE64_RS22095
uniprot id: R4WNZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

758793:BRPE64 RS12065
gene id: 758793:BRPE64_RS12065
uniprot id: R4WIY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

758793:BRPE64 RS08695
gene id: 758793:BRPE64_RS08695
uniprot id: R4WX60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS19115
gene id: 758793:BRPE64_RS19115
uniprot id: R4X2Q6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS07450
gene id: 758793:BRPE64_RS07450
uniprot id: R4WH10
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

758793:BRPE64 RS05610
gene id: 758793:BRPE64_RS05610
uniprot id: R4WGB4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

758793:BRPE64 RS05170
gene id: 758793:BRPE64_RS05170
uniprot id: R4WXP9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

758793:BRPE64 RS22580
gene id: 758793:BRPE64_RS22580
uniprot id: R4WP88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS28385
gene id: 758793:BRPE64_RS28385
uniprot id: R4X3V4
names: Similarity
messages: Belongs to the IlvD/Edd family.

758793:BRPE64 RS13610
gene id: 758793:BRPE64_RS13610
uniprot id: R4X0R4
names: Similarity
messages: Belongs to the GSP N family.

758793:BRPE64 RS01090
gene id: 758793:BRPE64_RS01090
uniprot id: R4WVQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PagL family.
messages: Cell outer membrane
messages: Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety.
messages: Homodimer.

758793:BRPE64 RS27325
gene id: 758793:BRPE64_RS27325
uniprot id: R4X049
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS17380
gene id: 758793:BRPE64_RS17380
uniprot id: R4X238
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

758793:BRPE64 RS15195
gene id: 758793:BRPE64_RS15195
uniprot id: R4WK37
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

758793:BRPE64 RS21495
gene id: 758793:BRPE64_RS21495
uniprot id: R4WNR5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS07085
gene id: 758793:BRPE64_RS07085
uniprot id: R4WWC5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

758793:BRPE64 RS01045
gene id: 758793:BRPE64_RS01045
uniprot id: R4WVP0
names: Similarity
messages: Belongs to the YciI family.

758793:BRPE64 RS08020
gene id: 758793:BRPE64_RS08020
uniprot id: R4WR77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

758793:BRPE64 RS05985
gene id: 758793:BRPE64_RS05985
uniprot id: R4WGG1
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS12340
gene id: 758793:BRPE64_RS12340
uniprot id: R4WIU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

758793:BRPE64 RS22200
gene id: 758793:BRPE64_RS22200
uniprot id: R4X1X7
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS15710
gene id: 758793:BRPE64_RS15710
uniprot id: R4WZN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

758793:BRPE64 RS12330
gene id: 758793:BRPE64_RS12330
uniprot id: R4WYH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

758793:BRPE64 RS09185
gene id: 758793:BRPE64_RS09185
uniprot id: R4WHK2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS05420
gene id: 758793:BRPE64_RS05420
uniprot id: R4WG94
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

758793:BRPE64 RS22830
gene id: 758793:BRPE64_RS22830
uniprot id: R4WPD2
names: Similarity
messages: Belongs to the transketolase family.

758793:BRPE64 RS04735
gene id: 758793:BRPE64_RS04735
uniprot id: R4WGA0
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

758793:BRPE64 RS08295
gene id: 758793:BRPE64_RS08295
uniprot id: R4WH93
names: Similarity
messages: Belongs to the UPF0246 family.

758793:BRPE64 RS24815
gene id: 758793:BRPE64_RS24815
uniprot id: R4WQJ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758793:BRPE64 RS21275
gene id: 758793:BRPE64_RS21275
uniprot id: R4WNJ4
names: Similarity
messages: Belongs to the GST superfamily.

758793:BRPE64 RS19925
gene id: 758793:BRPE64_RS19925
uniprot id: R4WMR0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

758793:BRPE64 RS12465
gene id: 758793:BRPE64_RS12465
uniprot id: R4WIW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

758793:BRPE64 RS21680
gene id: 758793:BRPE64_RS21680
uniprot id: R4X3E3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

758793:BRPE64 RS08590
gene id: 758793:BRPE64_RS08590
uniprot id: R4WYY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

758793:BRPE64 RS21485
gene id: 758793:BRPE64_RS21485
uniprot id: R4X1Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS10860
gene id: 758793:BRPE64_RS10860
uniprot id: R4WI53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

758793:BRPE64 RS21610
gene id: 758793:BRPE64_RS21610
uniprot id: R4WNT3
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS24520
gene id: 758793:BRPE64_RS24520
uniprot id: R4X2S4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS00905
gene id: 758793:BRPE64_RS00905
uniprot id: R4WF03
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

758793:BRPE64 RS04980
gene id: 758793:BRPE64_RS04980
uniprot id: R4WGC8
names: Subcellular Location Annotation
messages: Periplasm

758793:BRPE64 RS31475
gene id: 758793:BRPE64_RS31475
uniprot id: A0A060PH65
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS23235
gene id: 758793:BRPE64_RS23235
uniprot id: R4WPX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

758793:BRPE64 RS23285
gene id: 758793:BRPE64_RS23285
uniprot id: R4WPY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS01825
gene id: 758793:BRPE64_RS01825
uniprot id: R4WF24
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

758793:BRPE64 RS24540
gene id: 758793:BRPE64_RS24540
uniprot id: R4X2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS28510
gene id: 758793:BRPE64_RS28510
uniprot id: R4WT35
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS18800
gene id: 758793:BRPE64_RS18800
uniprot id: R4WX35
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

758793:BRPE64 RS08740
gene id: 758793:BRPE64_RS08740
uniprot id: R4WRK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

758793:BRPE64 RS13015
gene id: 758793:BRPE64_RS13015
uniprot id: R4WTY5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS26770
gene id: 758793:BRPE64_RS26770
uniprot id: R4WZZ1
names: Similarity
messages: Belongs to the peptidase C59 family.

758793:BRPE64 RS08000
gene id: 758793:BRPE64_RS08000
uniprot id: R4WWU5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS08790
gene id: 758793:BRPE64_RS08790
uniprot id: R4WX72
names: Similarity
messages: Belongs to the RecJ family.

758793:BRPE64 RS11525
gene id: 758793:BRPE64_RS11525
uniprot id: R4WIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS05835
gene id: 758793:BRPE64_RS05835
uniprot id: R4WVK3
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

758793:BRPE64 RS03970
gene id: 758793:BRPE64_RS03970
uniprot id: R4WNU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS06610
gene id: 758793:BRPE64_RS06610
uniprot id: R4WQD9
names: Similarity
messages: Belongs to the BolA/IbaG family.

758793:BRPE64 RS05755
gene id: 758793:BRPE64_RS05755
uniprot id: R4WGL0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS14435
gene id: 758793:BRPE64_RS14435
uniprot id: R4WUU7
names: Similarity
messages: Belongs to the MlaA family.

758793:BRPE64 RS32150
gene id: 758793:BRPE64_RS32150
uniprot id: R4WTQ1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

758793:BRPE64 RS27410
gene id: 758793:BRPE64_RS27410
uniprot id: R4X4R0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

758793:BRPE64 RS25505
gene id: 758793:BRPE64_RS25505
uniprot id: R4WQZ4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

758793:BRPE64 RS08330
gene id: 758793:BRPE64_RS08330
uniprot id: R4WRC7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS20045
gene id: 758793:BRPE64_RS20045
uniprot id: R4WXI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

758793:BRPE64 RS14570
gene id: 758793:BRPE64_RS14570
uniprot id: R4X164
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS00785
gene id: 758793:BRPE64_RS00785
uniprot id: R4WEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

758793:BRPE64 RS10595
gene id: 758793:BRPE64_RS10595
uniprot id: R4WXV4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

758793:BRPE64 RS29715
gene id: 758793:BRPE64_RS29715
uniprot id: R4X475
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS19845
gene id: 758793:BRPE64_RS19845
uniprot id: R4X2Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

758793:BRPE64 RS06315
gene id: 758793:BRPE64_RS06315
uniprot id: R4WQ81
names: Similarity
messages: Belongs to the UPF0111 family.

758793:BRPE64 RS20170
gene id: 758793:BRPE64_RS20170
uniprot id: R4WXJ3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

758793:BRPE64 RS07595
gene id: 758793:BRPE64_RS07595
uniprot id: R4WYM7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

758793:BRPE64 RS00130
gene id: 758793:BRPE64_RS00130
uniprot id: R4WEK7
names: Similarity
messages: Belongs to the DprA/Smf family.

758793:BRPE64 RS09405
gene id: 758793:BRPE64_RS09405
uniprot id: R4WRZ7
names: Similarity
messages: Belongs to the SCO1/2 family.

758793:BRPE64 RS04700
gene id: 758793:BRPE64_RS04700
uniprot id: R4WXI7
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

758793:BRPE64 RS29390
gene id: 758793:BRPE64_RS29390
uniprot id: R4X0Y1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS05790
gene id: 758793:BRPE64_RS05790
uniprot id: R4WVJ3
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

758793:BRPE64 RS03240
gene id: 758793:BRPE64_RS03240
uniprot id: R4WFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
messages: Membrane

758793:BRPE64 RS14540
gene id: 758793:BRPE64_RS14540
uniprot id: R4WZB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

758793:BRPE64 RS01150
gene id: 758793:BRPE64_RS01150
uniprot id: R4WF25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

758793:BRPE64 RS11880
gene id: 758793:BRPE64_RS11880
uniprot id: R4X062
names: Subcellular Location Annotation
messages: Cytoplasm

758793:BRPE64 RS14125
gene id: 758793:BRPE64_RS14125
uniprot id: R4X0Y7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

758793:BRPE64 RS01180
gene id: 758793:BRPE64_RS01180
uniprot id: R4WEU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

758793:BRPE64 RS07095
gene id: 758793:BRPE64_RS07095
uniprot id: R4WGY5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758793:BRPE64 RS02105
gene id: 758793:BRPE64_RS02105
uniprot id: R4WF59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

758793:BRPE64 RS28270
gene id: 758793:BRPE64_RS28270
uniprot id: R4WSV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS09885
gene id: 758793:BRPE64_RS09885
uniprot id: R4WHT5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

758793:BRPE64 RS09550
gene id: 758793:BRPE64_RS09550
uniprot id: R4WHQ3
names: Similarity
messages: Belongs to the fabD family.

758793:BRPE64 RS12455
gene id: 758793:BRPE64_RS12455
uniprot id: R4WTN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

758793:BRPE64 RS06370
gene id: 758793:BRPE64_RS06370
uniprot id: R4WY40
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS15645
gene id: 758793:BRPE64_RS15645
uniprot id: R4WKC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS24430
gene id: 758793:BRPE64_RS24430
uniprot id: R4WZ30
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS11650
gene id: 758793:BRPE64_RS11650
uniprot id: R4WIN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

758793:BRPE64 RS15410
gene id: 758793:BRPE64_RS15410
uniprot id: R4X1E4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

758793:BRPE64 RS21515
gene id: 758793:BRPE64_RS21515
uniprot id: R4WNR9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

758793:BRPE64 RS02490
gene id: 758793:BRPE64_RS02490
uniprot id: R4WTS9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

758793:BRPE64 RS29415
gene id: 758793:BRPE64_RS29415
uniprot id: R4X0Y5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS16060
gene id: 758793:BRPE64_RS16060
uniprot id: R4WVM3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

758793:BRPE64 RS00890
gene id: 758793:BRPE64_RS00890
uniprot id: R4WSS6
names: Similarity
messages: Belongs to the P(II) protein family.

758793:BRPE64 RS19745
gene id: 758793:BRPE64_RS19745
uniprot id: R4WMX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

758793:BRPE64 RS06430
gene id: 758793:BRPE64_RS06430
uniprot id: R4WGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS10215
gene id: 758793:BRPE64_RS10215
uniprot id: R4WSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS23860
gene id: 758793:BRPE64_RS23860
uniprot id: R4WQD8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

758793:BRPE64 RS07195
gene id: 758793:BRPE64_RS07195
uniprot id: R4WH22
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS13230
gene id: 758793:BRPE64_RS13230
uniprot id: R4WJD5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

758793:BRPE64 RS15250
gene id: 758793:BRPE64_RS15250
uniprot id: R4X1C8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS07035
gene id: 758793:BRPE64_RS07035
uniprot id: R4WQN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

758793:BRPE64 RS05760
gene id: 758793:BRPE64_RS05760
uniprot id: R4WPY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

758793:BRPE64 RS01900
gene id: 758793:BRPE64_RS01900
uniprot id: R4WFB1
names: Similarity
messages: Belongs to the HSP15 family.

758793:BRPE64 RS25460
gene id: 758793:BRPE64_RS25460
uniprot id: R4WQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

758793:BRPE64 RS14625
gene id: 758793:BRPE64_RS14625
uniprot id: R4X169
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

758793:BRPE64 RS06460
gene id: 758793:BRPE64_RS06460
uniprot id: R4WGT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS14760
gene id: 758793:BRPE64_RS14760
uniprot id: R4X179
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

758793:BRPE64 RS30215
gene id: 758793:BRPE64_RS30215
uniprot id: R4X191
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

758793:BRPE64 RS26400
gene id: 758793:BRPE64_RS26400
uniprot id: R4X4H2
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

758793:BRPE64 RS17205
gene id: 758793:BRPE64_RS17205
uniprot id: R4X219
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS06390
gene id: 758793:BRPE64_RS06390
uniprot id: R4WY44
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

758793:BRPE64 RS12510
gene id: 758793:BRPE64_RS12510
uniprot id: R4X0D9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

758793:BRPE64 RS11940
gene id: 758793:BRPE64_RS11940
uniprot id: R4WIW5
names: Similarity
messages: Belongs to the UxaA family.

758793:BRPE64 RS27870
gene id: 758793:BRPE64_RS27870
uniprot id: R4X4U8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

758793:BRPE64 RS13730
gene id: 758793:BRPE64_RS13730
uniprot id: R4WUD2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

758793:BRPE64 RS06985
gene id: 758793:BRPE64_RS06985
uniprot id: R4WGX8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS29805
gene id: 758793:BRPE64_RS29805
uniprot id: R4X132
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

758793:BRPE64 RS02885
gene id: 758793:BRPE64_RS02885
uniprot id: R4WNB7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

758793:BRPE64 RS28180
gene id: 758793:BRPE64_RS28180
uniprot id: R4X0H7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

758793:BRPE64 RS16925
gene id: 758793:BRPE64_RS16925
uniprot id: R4X1Y7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

758793:BRPE64 RS09435
gene id: 758793:BRPE64_RS09435
uniprot id: R4WHR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

758793:BRPE64 RS25070
gene id: 758793:BRPE64_RS25070
uniprot id: R4WQP4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS25285
gene id: 758793:BRPE64_RS25285
uniprot id: R4WR49
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS08775
gene id: 758793:BRPE64_RS08775
uniprot id: R4WZ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

758793:BRPE64 RS03100
gene id: 758793:BRPE64_RS03100
uniprot id: R4WNF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

758793:BRPE64 RS21830
gene id: 758793:BRPE64_RS21830
uniprot id: R4WP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

758793:BRPE64 RS15220
gene id: 758793:BRPE64_RS15220
uniprot id: R4WK41
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS22160
gene id: 758793:BRPE64_RS22160
uniprot id: R4X3I0
names: Similarity
messages: Belongs to the DapA family.

758793:BRPE64 RS00670
gene id: 758793:BRPE64_RS00670
uniprot id: R4WVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

758793:BRPE64 RS20375
gene id: 758793:BRPE64_RS20375
uniprot id: R4X336
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS18960
gene id: 758793:BRPE64_RS18960
uniprot id: R4WMF2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS02540
gene id: 758793:BRPE64_RS02540
uniprot id: R4WTT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

758793:BRPE64 RS12480
gene id: 758793:BRPE64_RS12480
uniprot id: R4WYJ4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

758793:BRPE64 RS14740
gene id: 758793:BRPE64_RS14740
uniprot id: R4WJW6
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

758793:BRPE64 RS11705
gene id: 758793:BRPE64_RS11705
uniprot id: R4X025
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

758793:BRPE64 RS08835
gene id: 758793:BRPE64_RS08835
uniprot id: R4WHF8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

758793:BRPE64 RS20920
gene id: 758793:BRPE64_RS20920
uniprot id: R4WXU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

758793:BRPE64 RS10900
gene id: 758793:BRPE64_RS10900
uniprot id: R4WXZ1
names: Similarity
messages: Belongs to the thioredoxin family.

758793:BRPE64 RS18105
gene id: 758793:BRPE64_RS18105
uniprot id: R4WLN8
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

758793:BRPE64 RS06645
gene id: 758793:BRPE64_RS06645
uniprot id: R4WY86
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

758793:BRPE64 RS16290
gene id: 758793:BRPE64_RS16290
uniprot id: R4WVR7
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

758793:BRPE64 RS18075
gene id: 758793:BRPE64_RS18075
uniprot id: R4WWN5
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS03775
gene id: 758793:BRPE64_RS03775
uniprot id: R4WNQ6
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS09775
gene id: 758793:BRPE64_RS09775
uniprot id: R4WHX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS08170
gene id: 758793:BRPE64_RS08170
uniprot id: R4WWX5
names: Similarity
messages: Belongs to the HesB/IscA family.

758793:BRPE64 RS19000
gene id: 758793:BRPE64_RS19000
uniprot id: R4WM74
names: Similarity
messages: Belongs to the leucine-binding protein family.

758793:BRPE64 RS09445
gene id: 758793:BRPE64_RS09445
uniprot id: R4WXG2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

758793:BRPE64 RS14020
gene id: 758793:BRPE64_RS14020
uniprot id: R4WJK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

758793:BRPE64 RS10050
gene id: 758793:BRPE64_RS10050
uniprot id: R4WSC0
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

758793:BRPE64 RS09875
gene id: 758793:BRPE64_RS09875
uniprot id: R4WXL7
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

758793:BRPE64 RS13205
gene id: 758793:BRPE64_RS13205
uniprot id: R4WJD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

758793:BRPE64 RS08190
gene id: 758793:BRPE64_RS08190
uniprot id: R4WRA3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

758793:BRPE64 RS26805
gene id: 758793:BRPE64_RS26805
uniprot id: R4X4K7
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS11095
gene id: 758793:BRPE64_RS11095
uniprot id: R4WY16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

758793:BRPE64 RS09950
gene id: 758793:BRPE64_RS09950
uniprot id: R4WZG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

758793:BRPE64 RS28825
gene id: 758793:BRPE64_RS28825
uniprot id: R4WTC8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

758793:BRPE64 RS01535
gene id: 758793:BRPE64_RS01535
uniprot id: R4WT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS04245
gene id: 758793:BRPE64_RS04245
uniprot id: R4WFU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

758793:BRPE64 RS13465
gene id: 758793:BRPE64_RS13465
uniprot id: R4WU75
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

758793:BRPE64 RS20785
gene id: 758793:BRPE64_RS20785
uniprot id: R4X369
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS26815
gene id: 758793:BRPE64_RS26815
uniprot id: R4WS33
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS32245
gene id: 758793:BRPE64_RS32245
uniprot id: R4WG92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

758793:BRPE64 RS22485
gene id: 758793:BRPE64_RS22485
uniprot id: R4WPE6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

758793:BRPE64 RS11465
gene id: 758793:BRPE64_RS11465
uniprot id: R4WIG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

758793:BRPE64 RS32120
gene id: 758793:BRPE64_RS32120
uniprot id: R4X0J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

758793:BRPE64 RS14100
gene id: 758793:BRPE64_RS14100
uniprot id: R4X0Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

758793:BRPE64 RS12000
gene id: 758793:BRPE64_RS12000
uniprot id: R4WYE5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

758793:BRPE64 RS26670
gene id: 758793:BRPE64_RS26670
uniprot id: R4WS12
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

758793:BRPE64 RS08635
gene id: 758793:BRPE64_RS08635
uniprot id: R4WHH9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

758793:BRPE64 RS09155
gene id: 758793:BRPE64_RS09155
uniprot id: R4WZ65
names: Similarity
messages: Belongs to the Nudix hydrolase family.

758793:BRPE64 RS12430
gene id: 758793:BRPE64_RS12430
uniprot id: R4WTN2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

758793:BRPE64 RS09560
gene id: 758793:BRPE64_RS09560
uniprot id: R4WS45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

758793:BRPE64 RS10750
gene id: 758793:BRPE64_RS10750
uniprot id: R4WI96
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS22100
gene id: 758793:BRPE64_RS22100
uniprot id: R4WP82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

758793:BRPE64 RS29170
gene id: 758793:BRPE64_RS29170
uniprot id: R4WTI0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

758793:BRPE64 RS15325
gene id: 758793:BRPE64_RS15325
uniprot id: R4WK66
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS33205
gene id: 758793:BRPE64_RS33205
uniprot id: R4WKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell outer membrane
messages: Membrane

758793:BRPE64 RS28395
gene id: 758793:BRPE64_RS28395
uniprot id: R4WSY6
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

758793:BRPE64 RS01685
gene id: 758793:BRPE64_RS01685
uniprot id: R4WT69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

758793:BRPE64 RS15800
gene id: 758793:BRPE64_RS15800
uniprot id: R4WVH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS01190
gene id: 758793:BRPE64_RS01190
uniprot id: R4WMA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

758793:BRPE64 RS01920
gene id: 758793:BRPE64_RS01920
uniprot id: R4WMR3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

758793:BRPE64 RS18210
gene id: 758793:BRPE64_RS18210
uniprot id: R4X0J0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

758793:BRPE64 RS07795
gene id: 758793:BRPE64_RS07795
uniprot id: R4WH39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

758793:BRPE64 RS00540
gene id: 758793:BRPE64_RS00540
uniprot id: R4WEW3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

758793:BRPE64 RS21955
gene id: 758793:BRPE64_RS21955
uniprot id: R4WP56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

758793:BRPE64 RS21070
gene id: 758793:BRPE64_RS21070
uniprot id: R4WNN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

758793:BRPE64 RS02120
gene id: 758793:BRPE64_RS02120
uniprot id: R4WTG8
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

758793:BRPE64 RS03345
gene id: 758793:BRPE64_RS03345
uniprot id: R4WNK0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

758793:BRPE64 RS01410
gene id: 758793:BRPE64_RS01410
uniprot id: R4WF51
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

758793:BRPE64 RS22565
gene id: 758793:BRPE64_RS22565
uniprot id: R4WYD8
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS29370
gene id: 758793:BRPE64_RS29370
uniprot id: R4X448
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

758793:BRPE64 RS05190
gene id: 758793:BRPE64_RS05190
uniprot id: R4WXQ2
names: Subcellular Location Annotation
messages: Membrane

758793:BRPE64 RS23335
gene id: 758793:BRPE64_RS23335
uniprot id: R4WPZ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.